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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TFCP2L1

Z-value: 0.86

Motif logo

Transcription factors associated with TFCP2L1

Gene Symbol Gene ID Gene Info
ENSG00000115112.8 TFCP2L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2L1hg38_v1_chr2_-_121285194_1212852090.251.7e-04Click!

Activity profile of TFCP2L1 motif

Sorted Z-values of TFCP2L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2L1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_176238365 11.16 ENST00000341199.10
ENST00000430704.6
ENST00000443967.5
ENST00000429602.7
SUMO interacting motifs containing 1
chr14_+_92323154 9.69 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr19_-_12551426 8.20 ENST00000416136.1
ENST00000339282.12
ENST00000596193.1
ENST00000428311.1
zinc finger protein 564
novel zinc finger protein
chr19_-_20661507 6.75 ENST00000612591.4
ENST00000595405.1
zinc finger protein 626
chr19_-_20661563 6.45 ENST00000601440.6
ENST00000291750.6
ENST00000595094.1
zinc finger protein 626
novel transcript
chr19_-_12484773 5.80 ENST00000397732.8
zinc finger protein 709
chr1_+_116111395 5.63 ENST00000684484.1
ENST00000369500.4
mab-21 like 3
chr17_-_28951285 4.95 ENST00000577226.5
PHD finger protein 12
chr15_+_74615808 4.90 ENST00000395066.9
ENST00000568139.6
ENST00000563297.5
ENST00000568488.6
CDC like kinase 3
chr14_-_90816381 4.52 ENST00000328459.11
tetratricopeptide repeat domain 7B
chr1_-_156248013 4.49 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr17_-_15263162 4.43 ENST00000674673.1
ENST00000675950.1
peripheral myelin protein 22
chr1_-_153565535 4.38 ENST00000368707.5
S100 calcium binding protein A2
chr10_-_73625951 4.31 ENST00000433394.1
ENST00000422491.7
ubiquitin specific peptidase 54
chr1_-_156248038 4.06 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr12_-_48004496 3.98 ENST00000337299.7
collagen type II alpha 1 chain
chr12_+_119178920 3.97 ENST00000281938.7
heat shock protein family B (small) member 8
chr12_+_119178953 3.91 ENST00000674542.1
heat shock protein family B (small) member 8
chr1_+_204870831 3.87 ENST00000404076.5
ENST00000539706.6
neurofascin
chr6_+_150683593 3.78 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr2_-_55923775 3.61 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EGF containing fibulin extracellular matrix protein 1
chr19_-_12140315 3.42 ENST00000418866.1
ENST00000600335.5
ENST00000334213.10
zinc finger protein 20
chr11_+_19712823 3.26 ENST00000396085.6
ENST00000349880.9
neuron navigator 2
chr20_+_45881218 3.24 ENST00000372523.1
zinc finger SWIM-type containing 1
chr4_+_105708772 3.17 ENST00000512828.1
ENST00000394730.7
ENST00000515279.6
ENST00000507281.5
glutathione S-transferase C-terminal domain containing
chr3_-_122416035 3.14 ENST00000330689.6
WD repeat domain 5B
chr20_-_3173516 3.10 ENST00000360342.7
ENST00000645462.1
ENST00000337576.7
leucine zipper tumor suppressor family member 3
chr3_+_38282294 3.08 ENST00000466887.5
ENST00000448498.6
solute carrier family 22 member 14
chr11_-_119423162 3.07 ENST00000284240.10
ENST00000524970.5
Thy-1 cell surface antigen
chr10_+_61901678 2.93 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr19_+_35138993 2.89 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr12_+_40692413 2.88 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
contactin 1
chr17_-_1628808 2.85 ENST00000301335.10
solute carrier family 43 member 2
chr9_+_88991440 2.84 ENST00000358157.3
sphingosine-1-phosphate receptor 3
chr19_-_6481769 2.83 ENST00000381480.7
ENST00000543576.5
ENST00000590173.5
DENN domain containing 1C
chr12_+_10212867 2.81 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr21_-_42879516 2.78 ENST00000330317.6
ENST00000398208.3
WD repeat domain 4
chr12_-_48004467 2.78 ENST00000380518.8
collagen type II alpha 1 chain
chr5_+_52989314 2.77 ENST00000296585.10
integrin subunit alpha 2
chr7_-_57132425 2.64 ENST00000319636.10
zinc finger protein 479
chr12_+_14419136 2.63 ENST00000545769.1
ENST00000428217.6
ENST00000396279.2
ENST00000542514.5
ENST00000536279.1
activating transcription factor 7 interacting protein
chr12_-_120904337 2.59 ENST00000353487.7
signal peptide peptidase like 3
chr17_+_44186953 2.59 ENST00000446571.7
ENST00000538716.7
ENST00000357984.7
transmembrane and ubiquitin like domain containing 2
chr13_-_36131286 2.59 ENST00000255448.8
ENST00000379892.4
doublecortin like kinase 1
chr8_+_116766497 2.57 ENST00000517814.1
ENST00000309822.7
ENST00000517820.1
UTP23 small subunit processome component
chr12_+_53097656 2.52 ENST00000301464.4
insulin like growth factor binding protein 6
chr19_-_20565746 2.51 ENST00000594419.1
zinc finger protein 737
chr15_+_89690804 2.49 ENST00000268130.12
ENST00000560294.5
ENST00000558000.1
WD repeat domain 93
chr2_+_90234809 2.43 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr1_+_26863140 2.41 ENST00000339276.6
stratifin
chr17_+_44187027 2.32 ENST00000587989.1
ENST00000590235.5
transmembrane and ubiquitin like domain containing 2
chr20_+_36154630 2.31 ENST00000338074.7
ENST00000636016.2
ENST00000373945.5
erythrocyte membrane protein band 4.1 like 1
chr19_-_9819032 2.27 ENST00000590277.1
ENST00000588922.5
ENST00000589626.5
ENST00000247977.9
ENST00000592067.1
ENST00000586469.1
F-box and leucine rich repeat protein 12
chr15_-_89690676 2.26 ENST00000561224.5
ENST00000300056.8
peroxisomal biogenesis factor 11 alpha
chr19_-_12365655 2.25 ENST00000242804.9
zinc finger protein 442
chr19_-_6591103 2.22 ENST00000423145.7
ENST00000245903.4
CD70 molecule
chr3_-_50567646 2.20 ENST00000426034.5
ENST00000441239.5
chromosome 3 open reading frame 18
chr3_+_38039199 2.19 ENST00000346219.7
ENST00000308059.11
DLEC1 cilia and flagella associated protein
chr16_-_65121930 2.18 ENST00000566827.5
ENST00000394156.7
ENST00000268603.9
ENST00000562998.1
cadherin 11
chr17_-_76027212 2.17 ENST00000586740.1
envoplakin
chr5_-_161546671 2.17 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr15_-_82699893 2.17 ENST00000642989.2
adaptor related protein complex 3 subunit beta 2
chr9_-_124507382 2.16 ENST00000373588.9
ENST00000620110.4
nuclear receptor subfamily 5 group A member 1
chr1_+_1425854 2.15 ENST00000378821.4
transmembrane protein 88B
chr3_+_71753834 2.14 ENST00000304411.3
G protein-coupled receptor 27
chr17_-_35063648 2.13 ENST00000394597.7
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr5_+_141359970 2.13 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr1_-_225941212 2.08 ENST00000366820.10
left-right determination factor 2
chrX_+_49922559 2.07 ENST00000376091.8
chloride voltage-gated channel 5
chr19_+_24087147 2.05 ENST00000611359.3
ENST00000616028.2
zinc finger protein 254
chr11_-_78188588 2.04 ENST00000526208.5
ENST00000529350.1
ENST00000530018.5
ENST00000528776.1
ENST00000340067.4
potassium channel tetramerization domain containing 21
chr15_+_43594027 2.03 ENST00000453733.5
ENST00000441322.6
ENST00000627381.1
creatine kinase, mitochondrial 1B
chr13_-_36131352 2.02 ENST00000360631.8
doublecortin like kinase 1
chrX_-_107717054 2.01 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr1_-_161549892 2.01 ENST00000426740.7
Fc fragment of IgG receptor IIIa
chr3_-_50567711 2.00 ENST00000357203.8
chromosome 3 open reading frame 18
chr3_-_66500973 1.98 ENST00000383703.3
ENST00000273261.8
leucine rich repeats and immunoglobulin like domains 1
chr19_+_24087179 1.95 ENST00000339642.10
ENST00000357002.5
zinc finger protein 254
chr12_+_53380141 1.94 ENST00000551969.5
ENST00000327443.9
Sp1 transcription factor
chr16_+_30699155 1.94 ENST00000262518.9
Snf2 related CREBBP activator protein
chr16_+_27550127 1.91 ENST00000261588.9
katanin interacting protein
chr15_+_43693859 1.89 ENST00000413453.7
ENST00000415044.3
ENST00000626814.1
creatine kinase, mitochondrial 1A
chr1_-_225941383 1.89 ENST00000420304.6
left-right determination factor 2
chr19_+_40717091 1.87 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr5_+_80408031 1.86 ENST00000505560.5
ENST00000509562.2
zinc finger FYVE-type containing 16
chr11_-_128867364 1.86 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chr19_+_35138778 1.86 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr4_-_163332589 1.85 ENST00000296533.3
ENST00000509586.5
ENST00000504391.5
ENST00000512819.1
neuropeptide Y receptor Y1
chr19_+_48465837 1.85 ENST00000595676.1
novel protein
chr12_+_123633739 1.84 ENST00000618160.4
general transcription factor IIH subunit 3
chr12_-_52652207 1.81 ENST00000309680.4
keratin 2
chr14_+_32077280 1.81 ENST00000432921.5
ENST00000345122.8
ENST00000433497.5
Rho GTPase activating protein 5
chr12_+_123633819 1.80 ENST00000539994.5
ENST00000538845.5
ENST00000228955.11
ENST00000543341.7
ENST00000536375.5
general transcription factor IIH subunit 3
chr2_-_31138429 1.79 ENST00000349752.10
polypeptide N-acetylgalactosaminyltransferase 14
chr15_+_74174403 1.79 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine rich repeat
chr6_-_52995170 1.78 ENST00000370959.1
ENST00000370963.9
glutathione S-transferase alpha 4
chr20_+_45406035 1.78 ENST00000372723.7
ENST00000372722.7
dysbindin domain containing 2
chr1_-_161549793 1.77 ENST00000443193.6
Fc fragment of IgG receptor IIIa
chr1_-_112619108 1.77 ENST00000358039.9
ENST00000360743.8
ENST00000490067.5
ENST00000343210.11
ENST00000369666.5
suppression of tumorigenicity 7 like
chr5_+_80407994 1.77 ENST00000338008.9
ENST00000510158.5
zinc finger FYVE-type containing 16
chr14_-_106622837 1.76 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr15_-_89690775 1.76 ENST00000559170.1
peroxisomal biogenesis factor 11 alpha
chr1_-_161550591 1.76 ENST00000367967.7
ENST00000436743.6
ENST00000442336.1
Fc fragment of IgG receptor IIIa
chr19_-_9818808 1.72 ENST00000586651.5
ENST00000586073.1
F-box and leucine rich repeat protein 12
chr19_-_19821704 1.72 ENST00000443905.6
ENST00000590766.5
ENST00000587452.5
ENST00000545006.1
ENST00000590319.1
ENST00000587461.5
ENST00000450683.6
ENST00000540806.7
ENST00000590274.1
zinc finger protein 506
novel transcript
chr6_-_46954922 1.70 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr14_-_68979274 1.70 ENST00000394419.9
actinin alpha 1
chr11_+_68008542 1.69 ENST00000614849.4
aldehyde dehydrogenase 3 family member B1
chr17_-_35448742 1.68 ENST00000534689.5
ENST00000532210.5
ENST00000285013.11
ENST00000526861.5
ENST00000531588.1
schlafen family member 13
chr7_-_100158679 1.65 ENST00000456769.5
ENST00000316937.8
trafficking protein particle complex 14
chr2_+_240625237 1.63 ENST00000407714.1
G protein-coupled receptor 35
chr15_-_35085295 1.61 ENST00000528386.4
Nanog homeobox retrogene P8
chr15_-_51094897 1.61 ENST00000637513.2
TNF alpha induced protein 8 like 3
chr2_+_26764232 1.60 ENST00000344420.10
solute carrier family 35 member F6
chrX_+_137566119 1.59 ENST00000287538.10
Zic family member 3
chr11_-_128867268 1.58 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr1_-_161631032 1.58 ENST00000534776.1
ENST00000613418.4
ENST00000614870.4
Fc fragment of IgG receptor IIIb
chr9_+_137618986 1.56 ENST00000462484.5
ENST00000630754.2
ENST00000460843.6
ENST00000626216.2
ENST00000629335.2
euchromatic histone lysine methyltransferase 1
chr1_-_161631152 1.55 ENST00000421702.3
ENST00000650385.1
Fc fragment of IgG receptor IIIb
chr14_-_68979314 1.53 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
actinin alpha 1
chr5_-_177311882 1.52 ENST00000513169.1
ENST00000423571.6
ENST00000502529.1
ENST00000427908.6
MAX dimerization protein 3
chr5_-_161546708 1.51 ENST00000393959.6
gamma-aminobutyric acid type A receptor subunit beta2
chr19_-_20565769 1.50 ENST00000427401.9
zinc finger protein 737
chr4_+_113049616 1.49 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr3_+_69866217 1.49 ENST00000314589.10
melanocyte inducing transcription factor
chr5_-_161546970 1.48 ENST00000675303.1
gamma-aminobutyric acid type A receptor subunit beta2
chr8_+_54457927 1.47 ENST00000297316.5
SRY-box transcription factor 17
chr19_-_20039443 1.46 ENST00000595736.1
ENST00000593468.5
ENST00000596019.5
zinc finger protein 682
chr4_+_40193642 1.46 ENST00000617441.4
ENST00000503941.5
ras homolog family member H
chr14_-_68979076 1.45 ENST00000538545.6
ENST00000684639.1
actinin alpha 1
chr17_+_44187190 1.45 ENST00000319511.6
transmembrane and ubiquitin like domain containing 2
chr14_-_68979251 1.44 ENST00000438964.6
ENST00000679147.1
actinin alpha 1
chr17_-_1492660 1.44 ENST00000648651.1
myosin IC
chr2_+_188291911 1.42 ENST00000410051.5
GULP PTB domain containing engulfment adaptor 1
chr15_-_89690634 1.42 ENST00000561257.1
peroxisomal biogenesis factor 11 alpha
chr14_-_68979436 1.39 ENST00000193403.10
actinin alpha 1
chr18_-_48950960 1.36 ENST00000262158.8
SMAD family member 7
chr1_+_151540299 1.34 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
tuftelin 1
chr8_-_131040211 1.34 ENST00000377928.7
adenylate cyclase 8
chr14_-_68937942 1.34 ENST00000684182.1
actinin alpha 1
chr14_+_32077068 1.34 ENST00000396582.6
Rho GTPase activating protein 5
chr10_+_63133247 1.33 ENST00000435510.6
nuclear receptor binding factor 2
chr19_-_20039492 1.32 ENST00000397165.7
zinc finger protein 682
chr19_+_22634317 1.32 ENST00000456783.3
zinc finger protein 492
chr19_+_11965029 1.31 ENST00000592625.5
ENST00000358987.8
ENST00000586494.1
ENST00000343949.9
zinc finger protein 763
chr2_+_71453722 1.31 ENST00000409582.7
ENST00000409762.5
ENST00000413539.6
ENST00000429174.6
dysferlin
chr1_-_182604379 1.29 ENST00000367558.6
regulator of G protein signaling 16
chr15_-_82647960 1.28 ENST00000615198.4
cytoplasmic polyadenylation element binding protein 1
chr17_-_16569184 1.25 ENST00000448349.2
ENST00000395825.4
zinc finger protein 287
chr5_-_140043069 1.24 ENST00000289409.8
ENST00000358522.7
ENST00000289422.11
ENST00000541337.5
ENST00000361474.6
neuregulin 2
chr19_+_41219235 1.23 ENST00000359092.7
AXL receptor tyrosine kinase
chr19_-_55175031 1.23 ENST00000587067.1
synaptotagmin 5
chr1_-_211133945 1.21 ENST00000640044.1
ENST00000640566.1
potassium voltage-gated channel subfamily H member 1
chr2_-_136118142 1.21 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr22_+_31093358 1.21 ENST00000404574.5
smoothelin
chr14_+_58637934 1.21 ENST00000395153.8
dishevelled binding antagonist of beta catenin 1
chr19_+_47713412 1.19 ENST00000538399.1
ENST00000263277.8
EH domain containing 2
chr16_+_84294823 1.18 ENST00000568638.1
WAP four-disulfide core domain 1
chr10_-_121596117 1.18 ENST00000351936.11
fibroblast growth factor receptor 2
chr19_-_4065732 1.16 ENST00000601588.1
zinc finger and BTB domain containing 7A
chr16_+_283157 1.14 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
protein disulfide isomerase family A member 2
chr12_-_121274510 1.14 ENST00000392474.6
calcium/calmodulin dependent protein kinase kinase 2
chr11_+_96389985 1.14 ENST00000332349.5
JRK like
chr1_-_155857172 1.12 ENST00000361040.9
ENST00000368331.6
ENST00000271883.9
ENST00000620426.4
ENST00000622608.1
gon-4 like
chr17_+_28506320 1.10 ENST00000579795.6
forkhead box N1
chr17_+_44187210 1.08 ENST00000589785.1
ENST00000592825.1
ENST00000589184.5
transmembrane and ubiquitin like domain containing 2
chr7_+_43926419 1.07 ENST00000222402.8
ENST00000446008.5
ubiquitin conjugating enzyme E2 D4 (putative)
chr19_+_12064720 1.07 ENST00000550826.1
ENST00000439326.8
zinc finger protein 844
chr17_-_16569169 1.07 ENST00000395824.5
zinc finger protein 287
chr8_-_131040890 1.06 ENST00000286355.10
adenylate cyclase 8
chr14_-_106025628 1.04 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr10_+_71319249 1.03 ENST00000373189.6
ENST00000479577.2
solute carrier family 29 member 3
chr9_+_130053706 1.03 ENST00000372410.7
G protein-coupled receptor 107
chr16_+_84294853 1.02 ENST00000219454.10
WAP four-disulfide core domain 1
chr19_-_4338786 1.01 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr19_-_20039205 1.01 ENST00000358523.9
ENST00000397162.5
ENST00000601100.5
zinc finger protein 682
chr12_-_120369156 1.01 ENST00000257552.7
musashi RNA binding protein 1
chr19_+_19900935 1.01 ENST00000588146.1
ENST00000343769.6
zinc finger protein 93
chr12_+_57772587 1.01 ENST00000300209.13
EEF1A lysine methyltransferase 3
chr12_+_41188301 1.00 ENST00000402685.7
PDZ domain containing ring finger 4
chr18_-_31162849 1.00 ENST00000257197.7
ENST00000257198.6
desmocollin 1
chr10_+_63133279 0.99 ENST00000277746.11
nuclear receptor binding factor 2
chr4_-_173530219 0.99 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr11_-_18322122 0.98 ENST00000349215.8
ENST00000396253.7
ENST00000438420.6
HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
chr19_+_41219177 0.98 ENST00000301178.9
AXL receptor tyrosine kinase
chr11_+_61102465 0.98 ENST00000347785.8
ENST00000544014.1
CD5 molecule
chr10_-_122845850 0.97 ENST00000392790.6
CUB and zona pellucida like domains 1
chr20_+_63235899 0.96 ENST00000217169.8
baculoviral IAP repeat containing 7
chr17_+_42851167 0.95 ENST00000613571.1
ENST00000308423.7
amine oxidase copper containing 3
chr10_+_104641282 0.93 ENST00000369701.8
sortilin related VPS10 domain containing receptor 3
chr18_+_23949847 0.92 ENST00000588004.1
laminin subunit alpha 3
chr5_-_141618914 0.90 ENST00000518047.5
diaphanous related formin 1
chr10_-_126388455 0.89 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM metallopeptidase domain 12
chr20_+_63235883 0.89 ENST00000342412.10
baculoviral IAP repeat containing 7
chr2_+_111120906 0.88 ENST00000337565.9
ENST00000357757.6
ENST00000308659.12
ENST00000393256.8
ENST00000610735.4
ENST00000615946.4
ENST00000619294.4
ENST00000620862.4
ENST00000621302.4
ENST00000622509.4
ENST00000622612.4
BCL2 like 11
chr12_+_7789393 0.86 ENST00000229307.9
Nanog homeobox
chr3_+_40505992 0.85 ENST00000420891.5
ENST00000314529.10
ENST00000418905.1
zinc finger protein 620
chr14_+_96204679 0.84 ENST00000542454.2
ENST00000539359.1
ENST00000554311.2
ENST00000553811.1
bradykinin receptor B2
novel protein
chr19_-_12365628 0.84 ENST00000438182.5
zinc finger protein 442
chr12_-_52434363 0.84 ENST00000252245.6
keratin 75

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.4 GO:0044375 regulation of peroxisome size(GO:0044375)
1.0 3.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.8 4.7 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.7 3.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) glossopharyngeal nerve development(GO:0021563)
0.6 1.9 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.5 2.2 GO:0007538 primary sex determination(GO:0007538)
0.5 3.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.5 7.9 GO:0060174 limb bud formation(GO:0060174)
0.5 1.5 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996)
0.5 9.7 GO:0097186 amelogenesis(GO:0097186)
0.5 2.4 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.4 0.9 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.4 3.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.4 2.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.4 2.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.4 2.8 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.4 8.8 GO:0051639 actin filament network formation(GO:0051639)
0.4 2.6 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.4 2.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.4 1.1 GO:1902232 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.3 2.0 GO:0048840 otolith development(GO:0048840)
0.3 2.6 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 1.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 2.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.3 1.4 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.3 1.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.3 1.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.3 2.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.3 0.8 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.3 2.0 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 1.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 0.7 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.2 2.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.7 GO:0007227 signal transduction downstream of smoothened(GO:0007227)
0.2 1.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2 1.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.2 0.7 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2 4.4 GO:0032060 bleb assembly(GO:0032060)
0.2 5.4 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619) regulation of nodal signaling pathway(GO:1900107)
0.2 1.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 3.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 1.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 1.7 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 1.5 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.7 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.4 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.9 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 1.7 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 0.8 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 2.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 4.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.5 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 1.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.9 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.4 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 1.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.6 GO:0060992 response to fungicide(GO:0060992)
0.1 0.8 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.5 GO:0003431 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384)
0.1 1.9 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.7 GO:0043366 beta selection(GO:0043366)
0.1 1.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.8 GO:0003334 keratinocyte development(GO:0003334)
0.1 2.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 3.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 3.1 GO:0015695 organic cation transport(GO:0015695)
0.1 2.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.6 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.1 2.4 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 1.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 1.0 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.1 1.0 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1 2.9 GO:0016577 histone demethylation(GO:0016577)
0.1 0.3 GO:0097694 telomeric loop formation(GO:0031627) establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.9 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 1.8 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 2.9 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 3.4 GO:0010107 potassium ion import(GO:0010107)
0.1 2.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.4 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 1.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 3.9 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 2.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0010814 neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 3.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 5.3 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.3 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 2.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 4.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.9 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.8 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 5.3 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 2.2 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 2.3 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 1.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 4.3 GO:0043542 endothelial cell migration(GO:0043542)
0.0 3.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 1.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 1.0 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 1.9 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 3.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 5.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 2.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 1.3 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 1.6 GO:0070268 cornification(GO:0070268)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 3.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.7 GO:0035904 aorta development(GO:0035904)
0.0 1.3 GO:0042476 odontogenesis(GO:0042476)
0.0 1.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 10.6 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 1.0 GO:0043473 pigmentation(GO:0043473)
0.0 1.0 GO:0008037 cell recognition(GO:0008037)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.8 3.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.6 2.8 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.5 6.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 2.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.5 2.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.4 3.7 GO:0005614 interstitial matrix(GO:0005614)
0.3 8.8 GO:0005916 fascia adherens(GO:0005916)
0.3 2.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 1.4 GO:0045160 myosin I complex(GO:0045160)
0.3 4.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 4.9 GO:0016580 Sin3 complex(GO:0016580)
0.2 2.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2 1.2 GO:1990769 proximal neuron projection(GO:1990769)
0.2 5.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 3.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 1.4 GO:0016342 catenin complex(GO:0016342)
0.1 3.8 GO:0030057 desmosome(GO:0030057)
0.1 4.4 GO:0043218 compact myelin(GO:0043218)
0.1 1.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.9 GO:0005610 laminin-5 complex(GO:0005610)
0.1 5.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.2 GO:0033643 host cell part(GO:0033643)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.2 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 2.8 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.8 GO:0001533 cornified envelope(GO:0001533)
0.1 2.6 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 5.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 5.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 1.0 GO:0031082 BLOC complex(GO:0031082)
0.0 3.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 6.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 5.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 2.1 GO:0001772 immunological synapse(GO:0001772)
0.0 1.5 GO:0031430 M band(GO:0031430)
0.0 1.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.4 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 4.8 GO:0060076 excitatory synapse(GO:0060076)
0.0 3.5 GO:0005770 late endosome(GO:0005770)
0.0 23.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 4.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.2 GO:0032184 SUMO polymer binding(GO:0032184)
1.6 9.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.0 6.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.9 3.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.8 2.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.8 2.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.6 1.9 GO:0001601 peptide YY receptor activity(GO:0001601)
0.5 5.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.5 8.7 GO:0019864 IgG binding(GO:0019864)
0.4 3.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 2.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 2.8 GO:0038064 collagen receptor activity(GO:0038064) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 3.1 GO:0034235 GPI anchor binding(GO:0034235)
0.3 8.8 GO:0017166 vinculin binding(GO:0017166)
0.3 2.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 4.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 3.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 1.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 0.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.3 1.0 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2 3.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.2 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.9 GO:0004111 creatine kinase activity(GO:0004111)
0.2 2.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 2.0 GO:0043426 MRF binding(GO:0043426)
0.2 0.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 2.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 2.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 2.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 1.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 3.1 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 1.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 2.8 GO:0019215 intermediate filament binding(GO:0019215)
0.2 3.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 0.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.8 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 2.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 2.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.7 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 2.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.4 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 11.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 2.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 4.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 2.9 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 3.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 4.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 3.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.7 GO:0005113 patched binding(GO:0005113)
0.1 0.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 2.8 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.5 GO:0070888 E-box binding(GO:0070888)
0.0 1.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 4.6 GO:0002020 protease binding(GO:0002020)
0.0 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 3.7 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.3 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 2.6 GO:0008201 heparin binding(GO:0008201)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 7.4 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 5.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 6.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 2.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 7.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 6.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.0 PID BMP PATHWAY BMP receptor signaling
0.1 2.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 3.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 2.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.3 PID AURORA A PATHWAY Aurora A signaling
0.0 1.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 2.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 2.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 4.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 5.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 5.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 2.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 6.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 33.7 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 3.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 10.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 5.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 5.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 5.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 2.5 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation