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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for TFEC_MITF_ARNTL_BHLHE41
Z-value: 5.50
Motif logo
Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TFEC
|
ENSG00000105967.16 | TFEC |
|
MITF
|
ENSG00000187098.17 | MITF |
|
ARNTL
|
ENSG00000133794.20 | ARNTL |
|
BHLHE41
|
ENSG00000123095.6 | BHLHE41 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ARNTL | hg38_v1_chr11_+_13277639_13277877 | -0.47 | 1.4e-13 | Click! |
| TFEC | hg38_v1_chr7_-_116030750_116030813, hg38_v1_chr7_-_116030735_116030746, hg38_v1_chr7_-_115968302_115968319 | -0.22 | 1.1e-03 | Click! |
| MITF | hg38_v1_chr3_+_69936583_69936600, hg38_v1_chr3_+_69866217_69866230, hg38_v1_chr3_+_69739425_69739543, hg38_v1_chr3_+_69763726_69763811, hg38_v1_chr3_+_69763549_69763560 | 0.20 | 3.0e-03 | Click! |
| BHLHE41 | hg38_v1_chr12_-_26125023_26125047 | -0.09 | 1.7e-01 | Click! |
Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif
Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of TFEC_MITF_ARNTL_BHLHE41
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 23.2 | 116.2 | GO:1904636 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 12.5 | 12.5 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 8.8 | 35.1 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 8.5 | 101.8 | GO:0070495 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 7.7 | 54.1 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 7.6 | 22.9 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 7.3 | 22.0 | GO:0097698 | telomere maintenance via base-excision repair(GO:0097698) |
| 6.6 | 26.5 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 6.1 | 18.4 | GO:0060623 | regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283) |
| 6.1 | 30.3 | GO:1904925 | positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 6.0 | 29.8 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 5.9 | 23.5 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 5.6 | 16.8 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 5.6 | 27.8 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 5.3 | 10.6 | GO:0002339 | B cell selection(GO:0002339) |
| 4.8 | 14.4 | GO:0002368 | B cell cytokine production(GO:0002368) |
| 4.6 | 13.7 | GO:1902905 | positive regulation of fibril organization(GO:1902905) |
| 4.5 | 13.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 4.3 | 17.3 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 4.3 | 39.0 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 4.1 | 12.2 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 3.9 | 19.4 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 3.9 | 15.4 | GO:0009216 | adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) |
| 3.8 | 11.3 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 3.8 | 48.9 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 3.7 | 14.9 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 3.7 | 11.0 | GO:1902594 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 3.5 | 17.5 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 3.3 | 113.4 | GO:0090383 | phagosome acidification(GO:0090383) |
| 3.3 | 9.9 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 3.3 | 16.4 | GO:0033206 | meiotic cytokinesis(GO:0033206) |
| 3.2 | 28.7 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 3.1 | 3.1 | GO:0072048 | pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) |
| 3.1 | 21.6 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 3.0 | 20.9 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 3.0 | 8.9 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 2.9 | 8.8 | GO:0043311 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
| 2.9 | 37.7 | GO:0021769 | orbitofrontal cortex development(GO:0021769) |
| 2.8 | 22.5 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 2.8 | 11.1 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 2.6 | 7.8 | GO:1901355 | response to rapamycin(GO:1901355) |
| 2.4 | 7.2 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 2.4 | 7.1 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 2.3 | 6.9 | GO:0060903 | regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903) |
| 2.2 | 44.7 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 2.2 | 8.9 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 2.2 | 26.1 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 2.1 | 29.7 | GO:2000680 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 2.0 | 6.0 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 2.0 | 5.9 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 2.0 | 7.9 | GO:0009137 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 2.0 | 3.9 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 1.9 | 7.6 | GO:0051182 | coenzyme transport(GO:0051182) |
| 1.9 | 5.6 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
| 1.8 | 22.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 1.8 | 9.0 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 1.8 | 7.2 | GO:1904569 | regulation of mRNA binding(GO:1902415) regulation of selenocysteine incorporation(GO:1904569) |
| 1.8 | 5.4 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 1.7 | 5.2 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 1.7 | 5.1 | GO:0035732 | nitric oxide storage(GO:0035732) |
| 1.7 | 3.3 | GO:0072229 | proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) |
| 1.6 | 3.3 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 1.6 | 16.2 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 1.6 | 14.4 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 1.6 | 28.2 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 1.6 | 21.9 | GO:0046689 | response to mercury ion(GO:0046689) |
| 1.5 | 4.5 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 1.5 | 6.0 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 1.5 | 17.6 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 1.4 | 4.3 | GO:0043321 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 1.4 | 7.0 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 1.4 | 6.9 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 1.4 | 81.6 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 1.4 | 4.1 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 1.3 | 6.6 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 1.3 | 31.7 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 1.3 | 5.3 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 1.3 | 5.2 | GO:0072683 | T cell extravasation(GO:0072683) |
| 1.3 | 23.4 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 1.3 | 7.8 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 1.3 | 6.5 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 1.3 | 5.0 | GO:1990834 | response to odorant(GO:1990834) |
| 1.3 | 5.0 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 1.2 | 11.0 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 1.2 | 13.4 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 1.2 | 6.0 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 1.2 | 4.7 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 1.1 | 2.3 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 1.1 | 6.9 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 1.1 | 5.6 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 1.1 | 4.5 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 1.1 | 15.4 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
| 1.1 | 21.8 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 1.0 | 11.5 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 1.0 | 7.1 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 1.0 | 1.0 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
| 1.0 | 3.0 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 1.0 | 14.1 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 1.0 | 4.0 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 1.0 | 3.9 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 1.0 | 11.6 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 1.0 | 2.9 | GO:0044007 | negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821) |
| 0.9 | 1.9 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
| 0.9 | 13.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.9 | 4.7 | GO:1902903 | regulation of fibril organization(GO:1902903) |
| 0.9 | 19.6 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.9 | 2.8 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 0.9 | 5.4 | GO:0006565 | L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264) |
| 0.9 | 15.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.9 | 57.7 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.9 | 0.9 | GO:1902954 | regulation of early endosome to recycling endosome transport(GO:1902954) |
| 0.9 | 2.7 | GO:0015746 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 0.9 | 2.7 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.9 | 2.7 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 0.9 | 12.1 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.8 | 2.5 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 0.8 | 9.9 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.8 | 2.4 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
| 0.8 | 5.7 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.8 | 4.8 | GO:0060449 | bud elongation involved in lung branching(GO:0060449) |
| 0.8 | 4.8 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.8 | 2.4 | GO:2000176 | regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 0.8 | 3.0 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 0.7 | 8.9 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.7 | 2.2 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 0.7 | 7.4 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.7 | 11.0 | GO:0009125 | nucleoside monophosphate catabolic process(GO:0009125) |
| 0.7 | 30.8 | GO:0034724 | DNA replication-independent nucleosome organization(GO:0034724) |
| 0.7 | 8.8 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.7 | 6.5 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.7 | 2.9 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 0.7 | 5.7 | GO:0045627 | positive regulation of T-helper 1 cell differentiation(GO:0045627) |
| 0.7 | 2.1 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.7 | 3.5 | GO:0060613 | fat pad development(GO:0060613) |
| 0.7 | 9.7 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.7 | 6.9 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.7 | 6.1 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.7 | 2.0 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.7 | 4.7 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.6 | 2.6 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.6 | 7.6 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.6 | 1.8 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.6 | 4.3 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.6 | 9.0 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.6 | 3.0 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.6 | 7.6 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.6 | 2.3 | GO:0006726 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.6 | 4.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.6 | 13.0 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.6 | 6.7 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.6 | 4.5 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.5 | 2.1 | GO:0072719 | smooth muscle hyperplasia(GO:0014806) cellular response to cisplatin(GO:0072719) |
| 0.5 | 2.6 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.5 | 1.6 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.5 | 1.6 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.5 | 4.7 | GO:0015816 | glycine transport(GO:0015816) |
| 0.5 | 4.7 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.5 | 2.0 | GO:0021823 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923) |
| 0.5 | 4.4 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.5 | 7.3 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.5 | 4.4 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 0.5 | 3.9 | GO:0002759 | regulation of antimicrobial humoral response(GO:0002759) |
| 0.5 | 2.9 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.5 | 1.9 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.5 | 2.9 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.5 | 2.4 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.5 | 2.8 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.5 | 2.3 | GO:0098706 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.5 | 2.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.5 | 4.6 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 0.5 | 6.5 | GO:1904869 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 0.5 | 3.7 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.5 | 1.9 | GO:0036506 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.5 | 3.6 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.4 | 1.3 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 0.4 | 3.5 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.4 | 3.9 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.4 | 4.3 | GO:0015936 | coenzyme A metabolic process(GO:0015936) |
| 0.4 | 3.4 | GO:0042262 | dGTP catabolic process(GO:0006203) DNA protection(GO:0042262) dATP catabolic process(GO:0046061) |
| 0.4 | 2.5 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.4 | 2.5 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.4 | 1.6 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.4 | 1.6 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.4 | 3.1 | GO:0018126 | protein hydroxylation(GO:0018126) |
| 0.4 | 21.4 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.4 | 1.9 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 0.4 | 1.1 | GO:0001545 | primary ovarian follicle growth(GO:0001545) |
| 0.4 | 2.6 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.4 | 4.7 | GO:0042407 | cristae formation(GO:0042407) |
| 0.4 | 3.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.4 | 11.2 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.3 | 5.2 | GO:0048569 | post-embryonic organ development(GO:0048569) |
| 0.3 | 3.8 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.3 | 1.0 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.3 | 1.4 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.3 | 1.0 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.3 | 2.3 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.3 | 1.3 | GO:0090269 | fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270) |
| 0.3 | 3.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.3 | 6.0 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
| 0.3 | 2.2 | GO:1905123 | regulation of glucosylceramidase activity(GO:1905123) |
| 0.3 | 1.6 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.3 | 33.8 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
| 0.3 | 12.8 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.3 | 1.5 | GO:0015988 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.3 | 2.9 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.3 | 3.8 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.3 | 2.3 | GO:0007549 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.3 | 2.9 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.3 | 1.4 | GO:1902044 | Fas signaling pathway(GO:0036337) regulation of Fas signaling pathway(GO:1902044) |
| 0.3 | 4.5 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.3 | 3.6 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 0.3 | 4.7 | GO:0048535 | lymph node development(GO:0048535) |
| 0.3 | 1.6 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.3 | 0.8 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.3 | 5.7 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.3 | 3.5 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.3 | 3.4 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.2 | 1.2 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.2 | 8.3 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.2 | 13.0 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.2 | 8.8 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.2 | 4.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.2 | 20.3 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.2 | 7.8 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 0.2 | 20.5 | GO:0043297 | apical junction assembly(GO:0043297) |
| 0.2 | 1.6 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 0.2 | 0.2 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 0.2 | 1.1 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.2 | 0.9 | GO:0051572 | negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572) |
| 0.2 | 21.3 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.2 | 2.1 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.2 | 3.7 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.2 | 1.2 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.2 | 2.9 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.2 | 5.6 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.2 | 1.5 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
| 0.2 | 7.2 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.2 | 2.5 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.2 | 15.8 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.2 | 0.7 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 0.2 | 1.1 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.2 | 1.3 | GO:0031087 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.2 | 12.8 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.2 | 11.9 | GO:0002209 | behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) |
| 0.2 | 0.7 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 0.2 | 8.2 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
| 0.2 | 4.7 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.2 | 1.7 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.2 | 1.9 | GO:0021840 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129) |
| 0.2 | 0.5 | GO:0014057 | positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) |
| 0.2 | 4.8 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.2 | 1.4 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.1 | 0.4 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.1 | 14.4 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.1 | 2.5 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.1 | 2.2 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.1 | 8.4 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.1 | 7.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 5.1 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.1 | 4.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.1 | 1.9 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 0.1 | 10.2 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.1 | 3.4 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.1 | 7.9 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.1 | 0.4 | GO:1900175 | regulation of nodal signaling pathway(GO:1900107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.1 | 1.2 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 0.1 | 1.0 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 2.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 6.3 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 3.1 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.1 | 2.8 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.1 | 4.9 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.1 | 0.3 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.1 | 0.6 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.1 | 1.2 | GO:0035278 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 1.1 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 1.0 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.1 | 1.1 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 1.1 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 1.9 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 0.6 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 5.0 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.1 | 0.2 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.1 | 2.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 2.1 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.1 | 0.3 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.1 | 8.0 | GO:0048565 | digestive tract development(GO:0048565) |
| 0.1 | 3.6 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.1 | 3.8 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
| 0.1 | 0.7 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.1 | 1.0 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.1 | 1.7 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.1 | 0.2 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 0.1 | 0.4 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.1 | 1.0 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.1 | 3.7 | GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) |
| 0.1 | 0.6 | GO:0090382 | phagosome maturation(GO:0090382) |
| 0.1 | 0.3 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.0 | 0.3 | GO:0043928 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.1 | GO:0060581 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581) |
| 0.0 | 0.1 | GO:0043335 | protein unfolding(GO:0043335) |
| 0.0 | 0.5 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.0 | 0.2 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
| 0.0 | 4.4 | GO:0015992 | proton transport(GO:0015992) |
| 0.0 | 0.2 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.0 | 11.1 | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.0 | 0.1 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.0 | 0.4 | GO:0045008 | depyrimidination(GO:0045008) |
| 0.0 | 1.5 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 1.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 1.3 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 1.0 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.4 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.0 | 0.2 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.0 | 2.2 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.2 | GO:0019323 | pentose catabolic process(GO:0019323) |
| 0.0 | 0.8 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.0 | 1.2 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.0 | 1.3 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 1.9 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.0 | 1.0 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.5 | GO:0000154 | rRNA modification(GO:0000154) |
| 0.0 | 0.2 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.0 | 2.3 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 1.6 | GO:0045931 | positive regulation of mitotic cell cycle(GO:0045931) |
| 0.0 | 0.2 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 0.1 | GO:0001302 | replicative cell aging(GO:0001302) strand invasion(GO:0042148) |
| 0.0 | 1.4 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 0.2 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
| 0.0 | 0.6 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.0 | 1.1 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 19.5 | 116.8 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 10.8 | 54.1 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 7.7 | 30.8 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 7.6 | 22.9 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 7.2 | 28.7 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 7.1 | 21.4 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 4.9 | 39.5 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 4.8 | 19.4 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 4.6 | 18.4 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 4.5 | 44.7 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 3.6 | 14.3 | GO:0071986 | Ragulator complex(GO:0071986) |
| 3.3 | 33.0 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 3.0 | 29.7 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 2.9 | 17.3 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 2.7 | 31.9 | GO:0071203 | WASH complex(GO:0071203) |
| 2.6 | 15.8 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 2.6 | 18.0 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 2.5 | 7.5 | GO:0033597 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 2.5 | 7.5 | GO:0071817 | MMXD complex(GO:0071817) |
| 2.5 | 29.7 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 2.5 | 19.7 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 2.4 | 16.7 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 2.3 | 9.0 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 2.2 | 6.6 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 2.2 | 8.8 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
| 2.1 | 14.8 | GO:0031415 | NatA complex(GO:0031415) |
| 2.0 | 12.0 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 1.9 | 37.7 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 1.9 | 13.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 1.8 | 14.1 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 1.7 | 22.0 | GO:0042555 | MCM complex(GO:0042555) |
| 1.7 | 5.0 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 1.6 | 4.8 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 1.6 | 7.8 | GO:0016589 | NURF complex(GO:0016589) |
| 1.5 | 29.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 1.5 | 13.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 1.5 | 14.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 1.4 | 11.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 1.4 | 13.8 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 1.4 | 24.9 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 1.4 | 6.9 | GO:0033503 | HULC complex(GO:0033503) |
| 1.3 | 11.7 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 1.3 | 24.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 1.3 | 5.1 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 1.3 | 24.0 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 1.2 | 13.4 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 1.2 | 5.9 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 1.1 | 7.9 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 1.1 | 5.6 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 1.1 | 8.8 | GO:0000322 | storage vacuole(GO:0000322) |
| 1.1 | 3.3 | GO:0016469 | proton-transporting two-sector ATPase complex(GO:0016469) |
| 1.1 | 16.4 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 1.0 | 7.1 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 1.0 | 5.1 | GO:0031082 | BLOC complex(GO:0031082) |
| 1.0 | 50.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 1.0 | 7.9 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 1.0 | 5.9 | GO:0061617 | MICOS complex(GO:0061617) |
| 1.0 | 4.8 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
| 0.9 | 3.8 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 0.9 | 4.5 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.9 | 3.6 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.9 | 10.6 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.9 | 3.4 | GO:0035841 | growing cell tip(GO:0035838) new growing cell tip(GO:0035841) |
| 0.9 | 10.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.8 | 4.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.8 | 22.2 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.8 | 20.3 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.7 | 9.2 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 0.7 | 8.9 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.7 | 2.7 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.7 | 2.0 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.7 | 5.3 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.6 | 7.1 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.6 | 1.9 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.6 | 9.6 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.6 | 2.9 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.6 | 2.3 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.5 | 4.3 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 0.5 | 6.9 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.5 | 4.6 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.5 | 2.0 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.5 | 6.5 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.5 | 4.3 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.5 | 3.8 | GO:0000243 | commitment complex(GO:0000243) |
| 0.5 | 7.6 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.5 | 5.6 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.5 | 9.4 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.5 | 2.8 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.4 | 1.8 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
| 0.4 | 6.2 | GO:0090543 | Flemming body(GO:0090543) |
| 0.4 | 9.0 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.4 | 68.3 | GO:0000776 | kinetochore(GO:0000776) |
| 0.4 | 11.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.4 | 8.9 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.4 | 3.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.4 | 4.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.4 | 3.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.4 | 2.6 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.4 | 1.8 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.4 | 9.9 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.3 | 7.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.3 | 2.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.3 | 1.5 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.3 | 4.2 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.3 | 3.0 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.3 | 9.6 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.3 | 3.2 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.3 | 41.4 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.3 | 3.6 | GO:0030478 | actin cap(GO:0030478) |
| 0.3 | 0.8 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.3 | 9.4 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.2 | 31.2 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.2 | 5.2 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.2 | 0.7 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.2 | 6.7 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 0.2 | 2.6 | GO:0002102 | podosome(GO:0002102) |
| 0.2 | 11.2 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.2 | 1.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 2.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.2 | 26.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.2 | 1.5 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.2 | 2.7 | GO:0030677 | ribonuclease P complex(GO:0030677) |
| 0.2 | 1.2 | GO:0020016 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.2 | 15.1 | GO:0031970 | organelle envelope lumen(GO:0031970) |
| 0.2 | 1.5 | GO:0030904 | retromer complex(GO:0030904) |
| 0.2 | 10.9 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.2 | 2.1 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.2 | 9.8 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.2 | 1.0 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.2 | 16.7 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.2 | 31.7 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.2 | 0.5 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.2 | 7.2 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.2 | 9.4 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
| 0.2 | 2.4 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.2 | 7.2 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 1.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 9.4 | GO:0018995 | host(GO:0018995) host cell(GO:0043657) |
| 0.1 | 1.0 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 1.0 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.1 | 4.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 0.3 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 19.3 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 10.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 4.0 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 0.7 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.1 | 14.6 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.1 | 3.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 8.4 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 3.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 4.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 39.2 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 0.5 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.1 | 16.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 1.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.1 | 2.4 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 8.5 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.1 | 4.4 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 24.5 | GO:0031975 | organelle envelope(GO:0031967) envelope(GO:0031975) |
| 0.0 | 17.6 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 2.1 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 2.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 3.4 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 2.4 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 1.4 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.8 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 0.1 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 0.4 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.4 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 1.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.3 | GO:0045335 | phagocytic vesicle(GO:0045335) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.4 | 33.7 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 8.2 | 24.6 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 7.8 | 23.5 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 7.1 | 28.2 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 6.9 | 41.3 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 6.4 | 38.5 | GO:0004308 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 5.6 | 27.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 5.0 | 44.7 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 4.1 | 12.2 | GO:0070364 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364) |
| 3.9 | 54.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 3.9 | 15.4 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 3.8 | 22.9 | GO:0034046 | poly(G) binding(GO:0034046) |
| 3.8 | 19.0 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 3.8 | 15.0 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 3.7 | 81.1 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) |
| 3.3 | 127.5 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 3.2 | 19.4 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 3.0 | 9.0 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 2.9 | 40.3 | GO:0031386 | protein tag(GO:0031386) |
| 2.9 | 17.1 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 2.8 | 22.5 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 2.8 | 13.9 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 2.6 | 10.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 2.6 | 13.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 2.6 | 15.7 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 2.6 | 7.9 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 2.5 | 10.0 | GO:0043273 | CTPase activity(GO:0043273) |
| 2.4 | 11.8 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 2.2 | 8.8 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 2.1 | 16.7 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 1.9 | 5.6 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 1.9 | 5.6 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 1.9 | 11.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 1.8 | 8.9 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 1.8 | 7.0 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 1.8 | 5.3 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 1.7 | 5.1 | GO:0035731 | S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731) |
| 1.7 | 15.3 | GO:0008865 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 1.6 | 4.8 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 1.6 | 11.0 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 1.5 | 9.1 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 1.5 | 14.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 1.4 | 11.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 1.4 | 7.0 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 1.4 | 9.8 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 1.4 | 6.9 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 1.4 | 24.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 1.4 | 5.4 | GO:0070905 | serine binding(GO:0070905) |
| 1.3 | 6.6 | GO:0036033 | mediator complex binding(GO:0036033) |
| 1.3 | 25.0 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 1.3 | 17.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 1.3 | 28.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 1.3 | 6.4 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 1.3 | 6.3 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 1.2 | 3.7 | GO:0052839 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 1.2 | 8.5 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 1.1 | 6.9 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 1.1 | 3.4 | GO:0036219 | GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693) |
| 1.1 | 4.5 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 1.1 | 3.3 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 1.1 | 7.6 | GO:0000182 | rDNA binding(GO:0000182) |
| 1.0 | 10.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 1.0 | 22.9 | GO:0005537 | mannose binding(GO:0005537) |
| 1.0 | 7.2 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 1.0 | 7.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 1.0 | 3.9 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 1.0 | 3.9 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 1.0 | 8.7 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 1.0 | 4.8 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
| 0.9 | 22.7 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.9 | 42.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.9 | 6.4 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.9 | 4.5 | GO:0000104 | succinate dehydrogenase activity(GO:0000104) |
| 0.9 | 2.7 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 0.9 | 5.4 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.9 | 10.6 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.9 | 2.6 | GO:0004315 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 0.8 | 4.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.8 | 3.3 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 0.8 | 8.9 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.7 | 6.0 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.7 | 7.3 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.7 | 20.3 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.7 | 10.1 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.7 | 7.8 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.7 | 4.2 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.7 | 11.0 | GO:0005351 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.7 | 7.4 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.7 | 3.4 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.7 | 15.4 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.7 | 5.3 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.7 | 3.3 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.7 | 4.0 | GO:0008381 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.7 | 2.0 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.6 | 11.7 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.6 | 4.4 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 0.6 | 5.1 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.6 | 28.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.6 | 5.0 | GO:0015288 | porin activity(GO:0015288) |
| 0.6 | 9.0 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.6 | 3.0 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.6 | 3.6 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.6 | 11.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.6 | 2.3 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.6 | 5.2 | GO:0089720 | caspase binding(GO:0089720) |
| 0.6 | 2.3 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 0.6 | 9.0 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.6 | 3.9 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.6 | 13.3 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.5 | 8.2 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.5 | 4.3 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 0.5 | 14.8 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.5 | 7.1 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.5 | 22.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.5 | 2.9 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.5 | 26.2 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.5 | 2.4 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.5 | 35.3 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.4 | 8.6 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.4 | 2.6 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.4 | 1.7 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.4 | 4.7 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.4 | 2.1 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.4 | 11.2 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 0.4 | 2.9 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.4 | 25.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.4 | 15.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.4 | 9.3 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.4 | 2.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.4 | 2.3 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.4 | 1.1 | GO:0004963 | follicle-stimulating hormone receptor activity(GO:0004963) |
| 0.4 | 7.8 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.4 | 10.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.3 | 2.4 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.3 | 3.0 | GO:0004673 | protein histidine kinase activity(GO:0004673) |
| 0.3 | 5.0 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.3 | 2.3 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.3 | 23.4 | GO:0019003 | GDP binding(GO:0019003) |
| 0.3 | 0.6 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.3 | 1.4 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.3 | 2.8 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.3 | 6.9 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.3 | 5.3 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.3 | 2.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.3 | 1.8 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.2 | 2.0 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 1.0 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 0.2 | 33.0 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.2 | 6.0 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.2 | 1.7 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.2 | 10.4 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.2 | 76.1 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.2 | 10.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.2 | 39.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.2 | 5.4 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.2 | 4.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.2 | 7.0 | GO:0005416 | cation:amino acid symporter activity(GO:0005416) |
| 0.2 | 4.0 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.2 | 4.8 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 1.6 | GO:0052834 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.2 | 3.1 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.2 | 4.1 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.2 | 5.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 25.0 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.2 | 1.0 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.2 | 8.4 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.2 | 3.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.2 | 2.9 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.2 | 1.1 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.2 | 2.4 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.2 | 3.1 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.2 | 3.7 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.2 | 3.5 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.2 | 2.2 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
| 0.2 | 1.6 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.2 | 1.6 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.2 | 8.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 3.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.2 | 6.0 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.1 | 4.1 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 1.1 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.1 | 2.5 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 6.1 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 8.3 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
| 0.1 | 7.9 | GO:0004521 | endoribonuclease activity(GO:0004521) |
| 0.1 | 2.3 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.1 | 3.5 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.1 | 5.7 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 14.3 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 0.8 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.1 | 1.1 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 5.0 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 4.1 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 1.6 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.1 | 2.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 2.6 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.1 | 0.9 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 7.5 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 1.2 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.1 | 4.3 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.1 | 11.4 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.1 | 1.8 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 1.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 0.2 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.1 | 1.0 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 4.7 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.1 | 5.6 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.1 | 1.6 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 22.0 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 5.8 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.1 | 1.1 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 4.8 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.1 | 5.1 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.4 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 0.0 | 3.6 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.2 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.0 | 0.3 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.0 | 1.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.7 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.0 | 0.8 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 1.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 0.3 | GO:0035240 | dopamine binding(GO:0035240) |
| 0.0 | 1.0 | GO:0016859 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859) |
| 0.0 | 6.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.4 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.0 | 1.1 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.0 | 120.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 5.1 | 96.7 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 1.0 | 66.8 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.9 | 44.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.8 | 100.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.5 | 38.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.4 | 35.4 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.4 | 32.0 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.3 | 18.0 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.2 | 11.7 | PID ATR PATHWAY | ATR signaling pathway |
| 0.2 | 18.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.2 | 8.8 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 8.5 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.2 | 11.3 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.2 | 13.5 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.2 | 1.8 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.2 | 14.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.2 | 14.9 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.2 | 5.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 48.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 3.9 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.2 | 2.8 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.2 | 2.6 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 3.7 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.1 | 5.2 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 2.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 7.7 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 4.2 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 5.2 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 2.3 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 1.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 9.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 1.9 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 3.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 3.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.8 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 2.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.1 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.4 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.0 | 111.2 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 2.9 | 104.4 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 2.5 | 25.0 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 2.3 | 45.7 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 2.1 | 34.3 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 2.0 | 2.0 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 2.0 | 2.0 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 1.9 | 44.7 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 1.7 | 25.4 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 1.6 | 151.4 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 1.5 | 22.0 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.5 | 33.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 1.4 | 18.4 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 1.3 | 25.8 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 1.2 | 60.2 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 1.1 | 37.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 1.0 | 30.0 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.9 | 13.7 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.9 | 25.4 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.9 | 30.5 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.8 | 1.6 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.7 | 13.8 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.7 | 15.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.6 | 15.6 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.6 | 16.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.6 | 31.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.5 | 17.1 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.5 | 7.9 | REACTOME PURINE METABOLISM | Genes involved in Purine metabolism |
| 0.5 | 3.1 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.5 | 4.0 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.5 | 17.6 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.4 | 3.0 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.4 | 4.2 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.4 | 14.2 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.4 | 15.6 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.4 | 65.1 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.4 | 7.8 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.4 | 13.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.4 | 12.1 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.3 | 11.0 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.3 | 36.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.3 | 2.3 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.3 | 4.9 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.3 | 3.0 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.3 | 20.0 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.3 | 4.7 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 0.3 | 6.7 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.3 | 2.1 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.3 | 2.4 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.3 | 4.6 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.2 | 17.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.2 | 1.2 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.2 | 3.5 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.2 | 1.6 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.2 | 55.3 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 4.9 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.2 | 4.7 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.2 | 9.9 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.2 | 9.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.2 | 25.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 3.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.2 | 1.9 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.2 | 1.5 | REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE | Genes involved in p53-Dependent G1 DNA Damage Response |
| 0.2 | 20.4 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.1 | 6.9 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 2.0 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 8.1 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 2.3 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 0.9 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 1.8 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 8.4 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 2.6 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.1 | 2.7 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.1 | 2.0 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 1.1 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.1 | 3.6 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 0.8 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 1.7 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 2.7 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.1 | 2.2 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 0.1 | 1.1 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.1 | 1.9 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 1.9 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 2.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 0.5 | REACTOME SIGNALING BY WNT | Genes involved in Signaling by Wnt |
| 0.0 | 1.5 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 2.4 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 6.7 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.7 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.8 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 2.7 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 0.3 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 0.4 | REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |