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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TGIF1

Z-value: 6.68

Motif logo

Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
ENSG00000177426.22 TGIF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg38_v1_chr18_+_3451647_3451724-0.714.5e-35Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_+_56651335 23.11 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr4_+_127965429 22.85 ENST00000513371.1
ENST00000611882.1
abhydrolase domain containing 18
chr18_+_56651385 21.96 ENST00000615645.4
WD repeat domain 7
chr11_-_111910830 18.89 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr11_-_111910888 18.86 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr14_+_99684283 16.85 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr11_-_111923722 16.64 ENST00000527950.5
crystallin alpha B
chr1_-_11848345 16.33 ENST00000376476.1
natriuretic peptide A
chr2_-_71227055 15.38 ENST00000244221.9
poly(A) binding protein interacting protein 2B
chr1_-_149917826 14.41 ENST00000369145.1
ENST00000369146.8
synaptic vesicle glycoprotein 2A
chr18_+_34976928 13.95 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr4_+_113116676 13.93 ENST00000671971.1
ENST00000672240.1
ENST00000673240.1
ENST00000673363.1
ankyrin 2
chr19_+_44905785 13.66 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr22_-_19524400 12.66 ENST00000618236.2
claudin 5
chr1_-_11847772 12.12 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr4_+_127965394 12.09 ENST00000645843.2
ENST00000388795.9
abhydrolase domain containing 18
chr10_+_84245038 11.82 ENST00000650682.1
ENST00000358110.7
ENST00000651237.1
ENST00000652122.1
ENST00000652092.2
ENST00000359452.9
ENST00000483744.6
retinal G protein coupled receptor
chr7_+_95772506 11.49 ENST00000537881.5
ENST00000447467.6
ENST00000524053.5
ENST00000324972.10
ENST00000630942.2
ENST00000437599.5
ENST00000359388.8
ENST00000413338.5
dynein cytoplasmic 1 intermediate chain 1
chr14_-_21024092 11.47 ENST00000554398.5
NDRG family member 2
chr14_-_21023954 11.26 ENST00000554094.5
NDRG family member 2
chr16_+_50742059 10.64 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr7_+_30911845 10.64 ENST00000652696.1
ENST00000311813.11
aquaporin 1 (Colton blood group)
chr19_-_36152427 10.59 ENST00000589154.1
ENST00000292907.8
cytochrome c oxidase subunit 7A1
chr12_+_112791738 10.32 ENST00000389385.9
rabphilin 3A
chr1_-_230714112 9.75 ENST00000681514.1
ENST00000366667.6
ENST00000680041.1
angiotensinogen
chr4_+_127965267 9.70 ENST00000398965.5
abhydrolase domain containing 18
chr3_+_45026296 9.47 ENST00000296130.5
C-type lectin domain family 3 member B
chr4_+_127965361 9.47 ENST00000444616.5
abhydrolase domain containing 18
chr10_-_72088972 9.38 ENST00000317376.8
ENST00000412663.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr10_-_123008687 9.35 ENST00000617859.4
IKAROS family zinc finger 5
chr3_-_18424533 9.35 ENST00000417717.6
SATB homeobox 1
chr22_-_50085331 9.22 ENST00000395876.6
modulator of VRAC current 1
chr4_+_165378998 9.20 ENST00000402744.9
carboxypeptidase E
chr19_-_46661132 9.09 ENST00000410105.2
ENST00000391916.7
dishevelled binding antagonist of beta catenin 3
chr9_+_135075520 8.78 ENST00000252854.8
olfactomedin 1
chr10_-_72088533 8.78 ENST00000373109.7
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr6_-_109094819 8.77 ENST00000436639.6
sestrin 1
chr22_-_50085414 8.62 ENST00000311597.10
modulator of VRAC current 1
chr5_+_141364153 8.50 ENST00000518069.2
protocadherin gamma subfamily A, 5
chr3_-_127822835 8.43 ENST00000453507.6
monoglyceride lipase
chrX_+_102125703 8.34 ENST00000329035.2
transcription elongation factor A like 2
chrX_+_110944285 8.29 ENST00000425146.5
ENST00000446737.5
p21 (RAC1) activated kinase 3
chrX_+_102125668 8.27 ENST00000372780.6
transcription elongation factor A like 2
chr10_-_97633485 8.25 ENST00000370635.3
ENST00000478953.1
ENST00000307450.11
MORN repeat containing 4
chr10_-_123008784 8.21 ENST00000368886.10
IKAROS family zinc finger 5
chr3_-_129161034 8.19 ENST00000418265.1
ENST00000393292.7
ENST00000273541.12
ENST00000393295.8
ISY1-RAB43 readthrough
ISY1 splicing factor homolog
chr6_-_83709141 8.18 ENST00000521743.5
synaptosome associated protein 91
chr6_-_83709019 8.05 ENST00000519779.5
ENST00000369694.6
ENST00000195649.10
synaptosome associated protein 91
chr5_-_132777229 8.05 ENST00000378721.8
ENST00000378719.7
ENST00000378701.5
septin 8
chr5_-_132777215 8.02 ENST00000458488.2
septin 8
chr7_-_137343688 7.91 ENST00000348225.7
pleiotrophin
chr20_+_1266263 7.88 ENST00000649598.1
ENST00000381867.6
ENST00000381873.7
syntaphilin
chr12_-_54584302 7.82 ENST00000553113.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr12_-_112382363 7.78 ENST00000682272.1
ENST00000377560.9
HECT domain E3 ubiquitin protein ligase 4
chr11_-_132943092 7.70 ENST00000612177.4
ENST00000541867.5
opioid binding protein/cell adhesion molecule like
chr4_+_87975829 7.60 ENST00000614857.5
secreted phosphoprotein 1
chr19_-_10010492 7.57 ENST00000264828.4
collagen type V alpha 3 chain
chr16_+_30699155 7.50 ENST00000262518.9
Snf2 related CREBBP activator protein
chrX_+_16719595 7.45 ENST00000380155.4
synapse associated protein 1
chr5_+_141489066 7.43 ENST00000252087.3
protocadherin gamma subfamily C, 5
chr9_-_76692181 7.13 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr7_+_97732046 6.91 ENST00000350485.8
ENST00000346867.4
ENST00000319273.10
tachykinin precursor 1
chr14_+_100376398 6.86 ENST00000554998.5
ENST00000402312.8
ENST00000335290.10
ENST00000554175.5
WD repeat domain 25
chr21_-_34615103 6.85 ENST00000313806.9
regulator of calcineurin 1
chr7_-_137343752 6.84 ENST00000393083.2
pleiotrophin
chr5_-_75052546 6.80 ENST00000652361.2
glucosaminyl (N-acetyl) transferase 4
chr8_+_38386303 6.78 ENST00000519476.6
leucine zipper and EF-hand containing transmembrane protein 2
chr15_-_42548763 6.73 ENST00000563454.5
ENST00000397130.8
ENST00000570160.1
ENST00000323443.6
leucine rich repeat containing 57
chr2_+_172860038 6.72 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr15_+_42548810 6.62 ENST00000568876.5
ENST00000568846.6
ENST00000562398.5
ENST00000260372.8
HAUS augmin like complex subunit 2
chrX_+_49879475 6.48 ENST00000621775.2
ubiquitin specific peptidase 27 X-linked
chr1_+_163068775 6.45 ENST00000421743.6
regulator of G protein signaling 4
chr17_-_68955332 6.39 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr10_+_119726118 6.36 ENST00000369081.3
ENST00000648262.1
inositol polyphosphate-5-phosphatase F
chr14_-_72894091 6.35 ENST00000556509.6
double PHD fingers 3
chr1_+_7784411 6.32 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chr3_+_4493471 6.29 ENST00000544951.6
ENST00000650294.1
inositol 1,4,5-trisphosphate receptor type 1
chr14_+_22515623 6.24 ENST00000390509.1
T cell receptor alpha joining 28
chr4_+_87975667 6.24 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chr16_+_2537997 6.22 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr11_+_12110569 6.17 ENST00000683283.1
ENST00000256194.8
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr6_-_13487593 6.13 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr9_-_35812238 6.13 ENST00000396638.7
ENST00000340291.6
sperm associated antigen 8
chr22_+_50508216 6.11 ENST00000420993.7
ENST00000395698.7
ENST00000395701.7
ENST00000523045.5
ENST00000299821.15
non-SMC condensin II complex subunit H2
chr12_+_101594849 6.10 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr19_-_45322867 6.10 ENST00000221476.4
creatine kinase, M-type
chr6_+_83067655 6.02 ENST00000237163.9
ENST00000349129.7
DOP1 leucine zipper like protein A
chr1_+_205504592 5.94 ENST00000506784.5
ENST00000360066.6
cyclin dependent kinase 18
chr17_+_70169516 5.92 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr3_-_127822455 5.89 ENST00000265052.10
monoglyceride lipase
chr12_+_108515262 5.71 ENST00000552695.6
ENST00000552758.1
ENST00000361549.2
FIC domain protein adenylyltransferase
chr19_-_55175031 5.61 ENST00000587067.1
synaptotagmin 5
chr3_-_142448028 5.59 ENST00000392981.7
5'-3' exoribonuclease 1
chr16_-_30571635 5.58 ENST00000563707.1
ENST00000567855.1
ENST00000223459.11
zinc finger protein 688
chr3_+_35680994 5.56 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr2_+_241188509 5.44 ENST00000674324.1
ENST00000274979.12
anoctamin 7
chr1_+_52726441 5.34 ENST00000294353.7
ENST00000545132.5
zyg-11 family member B, cell cycle regulator
chr18_-_55302613 5.33 ENST00000561831.7
transcription factor 4
chr5_-_19988179 5.31 ENST00000502796.5
ENST00000382275.6
ENST00000511273.1
cadherin 18
chr11_-_132943671 5.27 ENST00000331898.11
opioid binding protein/cell adhesion molecule like
chr10_+_119726041 5.26 ENST00000650623.2
ENST00000649251.1
inositol polyphosphate-5-phosphatase F
chr10_+_47300174 5.22 ENST00000580279.2
growth differentiation factor 10
chr11_-_111379268 5.20 ENST00000393067.8
POU class 2 homeobox associating factor 1
chr9_+_17135017 5.18 ENST00000380641.4
ENST00000380647.8
centlein
chr1_+_205504644 5.17 ENST00000429964.7
ENST00000443813.6
cyclin dependent kinase 18
chr14_-_21526312 5.08 ENST00000537235.2
spalt like transcription factor 2
chr10_-_5977492 5.07 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
interleukin 15 receptor subunit alpha
chr16_-_57186014 5.06 ENST00000566584.5
ENST00000566481.5
ENST00000566077.5
ENST00000564108.5
ENST00000309137.13
ENST00000565458.5
ENST00000566681.1
ENST00000567439.5
proteasome activator subunit 3 interacting protein 1
chr22_+_49853801 4.99 ENST00000216268.6
zinc finger BED-type containing 4
chr2_-_201071579 4.98 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
family with sequence similarity 126 member B
chr3_-_127823177 4.93 ENST00000434178.6
monoglyceride lipase
chr3_-_101513175 4.92 ENST00000394091.5
ENST00000394094.6
ENST00000394095.7
ENST00000348610.3
ENST00000314261.11
SUMO specific peptidase 7
chr2_+_172821575 4.90 ENST00000397087.7
Rap guanine nucleotide exchange factor 4
chr19_+_7888499 4.89 ENST00000618098.4
ENST00000306708.11
ENST00000600345.1
ENST00000598224.5
leucine rich repeat containing 8 VRAC subunit E
chr2_+_24491239 4.82 ENST00000348332.8
nuclear receptor coactivator 1
chr5_-_131994579 4.81 ENST00000379240.5
acyl-CoA synthetase long chain family member 6
chr12_-_108633864 4.78 ENST00000550948.2
selectin P ligand
chr9_-_33447553 4.77 ENST00000645858.1
ENST00000297991.6
aquaporin 3 (Gill blood group)
chr20_+_2295994 4.76 ENST00000381458.6
transglutaminase 3
chr1_+_101237009 4.70 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr4_-_86594037 4.69 ENST00000641050.1
ENST00000641831.1
ENST00000515400.3
ENST00000641391.1
ENST00000641157.1
ENST00000641737.1
ENST00000502302.6
ENST00000640527.1
ENST00000512046.2
ENST00000513186.7
mitogen-activated protein kinase 10
chr22_-_35617321 4.67 ENST00000397326.7
ENST00000442617.1
myoglobin
chr2_+_24491860 4.67 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr1_-_151146643 4.66 ENST00000613223.1
semaphorin 6C
chr19_-_14117729 4.65 ENST00000590853.5
ENST00000308677.9
protein kinase cAMP-activated catalytic subunit alpha
chr20_+_36573589 4.65 ENST00000373872.9
ENST00000650844.1
TGFB induced factor homeobox 2
chr8_-_20303955 4.64 ENST00000381569.5
leucine zipper tumor suppressor 1
chr6_-_41895359 4.61 ENST00000373006.5
ENST00000682992.1
ubiquitin specific peptidase 49
chr19_+_18919688 4.61 ENST00000247003.9
DEAD-box helicase 49
chr2_-_200864670 4.59 ENST00000621181.4
CDC like kinase 1
chr4_-_82561972 4.58 ENST00000454948.3
ENST00000449862.7
transmembrane protein 150C
chr8_-_41665261 4.58 ENST00000522231.5
ENST00000314214.12
ENST00000348036.8
ENST00000522543.5
ankyrin 1
chr2_-_200864561 4.57 ENST00000434813.3
CDC like kinase 1
chr3_+_4493340 4.56 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
inositol 1,4,5-trisphosphate receptor type 1
chr5_-_170297746 4.55 ENST00000046794.10
lymphocyte cytosolic protein 2
chr3_+_4493442 4.51 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
inositol 1,4,5-trisphosphate receptor type 1
chr3_-_127823235 4.51 ENST00000398104.5
monoglyceride lipase
chr16_-_53503192 4.45 ENST00000568596.5
ENST00000394657.12
ENST00000570004.5
ENST00000564497.1
ENST00000300245.8
AKT interacting protein
chr2_-_200864643 4.42 ENST00000321356.9
CDC like kinase 1
chr9_-_130043154 4.37 ENST00000355681.3
ENST00000446176.7
ENST00000443566.6
ENST00000420781.5
formin binding protein 1
chrX_+_136205982 4.36 ENST00000628568.1
four and a half LIM domains 1
chr4_+_76949807 4.33 ENST00000505788.5
ENST00000510515.5
ENST00000504637.5
septin 11
chr6_+_72366730 4.24 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr13_+_27919993 4.24 ENST00000381033.5
pancreatic and duodenal homeobox 1
chr17_+_28042660 4.21 ENST00000407008.8
nemo like kinase
chr18_+_24113341 4.19 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr10_+_18340821 4.18 ENST00000612743.1
ENST00000612134.4
calcium voltage-gated channel auxiliary subunit beta 2
chrX_-_49073989 4.17 ENST00000376386.3
ENST00000553851.3
PRA1 domain family member 2
chr17_+_17042433 4.14 ENST00000651222.2
myosin phosphatase Rho interacting protein
chr5_-_131994225 4.13 ENST00000543479.5
ENST00000431707.5
acyl-CoA synthetase long chain family member 6
chr4_+_54229261 4.12 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr11_+_46295126 4.11 ENST00000534787.1
cAMP responsive element binding protein 3 like 1
chr11_-_84317296 4.09 ENST00000280241.12
ENST00000398301.6
discs large MAGUK scaffold protein 2
chr17_-_27893339 4.05 ENST00000460380.6
ENST00000379102.8
ENST00000508862.5
ENST00000582441.1
LYR motif containing 9
novel protein
chr1_+_66533575 4.04 ENST00000684751.1
ENST00000683291.1
ENST00000682054.1
ENST00000435165.3
ENST00000684539.1
ENST00000681971.1
ENST00000682476.1
ENST00000684168.1
ENST00000371039.5
SH3GL interacting endocytic adaptor 1
chr2_-_86790825 4.04 ENST00000409781.1
ENST00000352580.7
CD8a molecule
chr3_-_142448060 4.03 ENST00000264951.8
5'-3' exoribonuclease 1
chr1_-_151146611 4.02 ENST00000341697.7
ENST00000368914.8
semaphorin 6C
chr5_-_78985249 4.00 ENST00000565165.2
arylsulfatase B
chr19_-_38224215 3.96 ENST00000355526.10
ENST00000420980.7
ENST00000614244.4
double PHD fingers 1
chr2_+_118088432 3.96 ENST00000245787.9
insulin induced gene 2
chr17_-_35578535 3.95 ENST00000225873.9
peroxisomal biogenesis factor 12
chr12_+_77830886 3.94 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr4_-_148444674 3.90 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr11_+_90134634 3.85 ENST00000534061.6
ENST00000321955.8
ENST00000525171.5
ENST00000375944.7
N-acetylated alpha-linked acidic dipeptidase 2
chr9_-_96778053 3.84 ENST00000375231.5
ENST00000223428.9
zinc finger protein 510
chr22_+_32357867 3.83 ENST00000249007.4
ret finger protein like 3
chr1_-_54406385 3.80 ENST00000610401.5
single stranded DNA binding protein 3
chr14_+_21317535 3.79 ENST00000382933.8
RPGR interacting protein 1
chr1_+_13389632 3.77 ENST00000376098.4
PRAME family member 17
chr4_-_46389351 3.77 ENST00000503806.5
ENST00000356504.5
ENST00000514090.5
ENST00000506961.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr1_-_156282799 3.75 ENST00000361813.5
SMG5 nonsense mediated mRNA decay factor
chr7_-_117323041 3.72 ENST00000491214.1
ENST00000265441.8
Wnt family member 2
chr19_-_39335999 3.70 ENST00000602185.5
ENST00000598034.5
ENST00000601387.5
ENST00000595636.1
ENST00000253054.12
ENST00000594700.5
ENST00000597595.6
glia maturation factor gamma
chr20_+_36573458 3.69 ENST00000373874.6
TGFB induced factor homeobox 2
chr3_-_184017863 3.69 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr14_+_31025634 3.68 ENST00000673317.1
ENST00000556232.6
ENST00000542754.7
ENST00000554345.6
ENST00000334725.8
ENST00000554609.6
ENST00000313566.11
adaptor related protein complex 4 subunit sigma 1
chr3_-_183555696 3.67 ENST00000341319.8
kelch like family member 6
chr2_+_33436304 3.64 ENST00000402538.7
RAS guanyl releasing protein 3
chr19_+_41397803 3.62 ENST00000269980.7
ENST00000542943.5
ENST00000457836.6
branched chain keto acid dehydrogenase E1 subunit alpha
chr1_-_160711803 3.62 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48 molecule
chr10_-_5977535 3.59 ENST00000379977.8
interleukin 15 receptor subunit alpha
chr11_-_6405405 3.58 ENST00000608645.5
ENST00000618005.4
ENST00000610474.4
ENST00000608394.5
ENST00000529519.5
amyloid beta precursor protein binding family B member 1
chr8_+_144517977 3.57 ENST00000527730.1
ENST00000292524.6
ENST00000529022.5
leucine rich repeat containing 14
chr1_-_16018005 3.57 ENST00000406363.2
ENST00000411503.5
ENST00000311890.14
ENST00000487046.1
heat shock protein family B (small) member 7
chr2_+_143129379 3.55 ENST00000295095.11
Rho GTPase activating protein 15
chr9_+_122264857 3.55 ENST00000344641.8
ENST00000441707.5
ENST00000373723.9
ENST00000373729.5
mitochondrial ribosome recycling factor
chr1_-_37947010 3.54 ENST00000458109.6
ENST00000373024.8
ENST00000373023.6
inositol polyphosphate-5-phosphatase B
chr4_+_158672237 3.54 ENST00000682734.1
electron transfer flavoprotein dehydrogenase
chr2_+_233060295 3.53 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr15_-_43266857 3.52 ENST00000349114.8
ENST00000220420.10
transglutaminase 5
chrX_-_100732100 3.51 ENST00000372981.1
ENST00000263033.9
synaptotagmin like 4
chr11_-_84720876 3.50 ENST00000648622.1
discs large MAGUK scaffold protein 2
chr1_-_109042093 3.46 ENST00000369962.8
ENST00000357672.7
ENST00000531337.1
ENST00000529074.1
ENST00000369965.8
WD repeat domain 47
chr1_+_245154963 3.38 ENST00000407071.7
kinesin family member 26B
chr17_-_37609361 3.33 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr22_+_35648438 3.32 ENST00000409652.5
apolipoprotein L6
chr11_+_111977300 3.32 ENST00000615255.1
DIX domain containing 1
chr18_+_13611429 3.31 ENST00000587757.5
low density lipoprotein receptor class A domain containing 4
chr16_-_30123203 3.31 ENST00000395202.5
ENST00000395199.7
ENST00000263025.9
ENST00000322266.9
mitogen-activated protein kinase 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.5 GO:0046878 positive regulation of saliva secretion(GO:0046878)
5.7 28.4 GO:1901628 positive regulation of postsynaptic membrane organization(GO:1901628)
5.3 15.8 GO:1990108 protein linear deubiquitination(GO:1990108)
4.7 28.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
4.6 13.8 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
3.3 9.8 GO:0014873 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
3.2 54.4 GO:0007021 tubulin complex assembly(GO:0007021)
3.2 9.5 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
2.9 11.6 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
2.7 8.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
2.6 23.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
2.4 9.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.2 6.6 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
2.1 6.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
1.9 1.9 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
1.8 9.2 GO:0030070 insulin processing(GO:0030070)
1.8 5.4 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.7 15.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.7 15.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.7 16.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.5 5.9 GO:0090076 relaxation of skeletal muscle(GO:0090076)
1.4 10.1 GO:0002118 aggressive behavior(GO:0002118)
1.4 4.3 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
1.4 13.9 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.4 4.1 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.3 22.8 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.3 11.5 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.2 2.5 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
1.2 14.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
1.2 4.8 GO:0050902 leukocyte adhesive activation(GO:0050902)
1.2 3.6 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
1.2 4.8 GO:0070295 renal water absorption(GO:0070295)
1.1 15.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.1 18.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.1 4.2 GO:0010157 response to chlorate(GO:0010157)
1.1 3.2 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
1.0 4.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
1.0 4.1 GO:0021571 rhombomere 5 development(GO:0021571)
1.0 4.0 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
1.0 3.0 GO:0060366 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
1.0 3.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
1.0 3.0 GO:0090273 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
1.0 8.8 GO:0003190 atrioventricular valve formation(GO:0003190)
1.0 2.9 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.9 2.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.9 3.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.9 9.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.8 3.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.8 3.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.8 4.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.8 8.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.8 3.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.7 2.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.7 11.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.7 4.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.7 2.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.6 2.6 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.6 5.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.6 9.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.6 3.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.6 4.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.6 1.8 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.6 1.8 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.6 4.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 6.4 GO:0042908 xenobiotic transport(GO:0042908)
0.6 4.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.6 7.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.6 3.3 GO:0000189 MAPK import into nucleus(GO:0000189)
0.6 23.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 3.8 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.5 2.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.5 16.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 5.4 GO:0051126 negative regulation of actin nucleation(GO:0051126)
0.5 3.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.5 1.6 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.5 3.7 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.5 6.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.5 15.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.5 1.5 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.5 2.8 GO:0018343 protein farnesylation(GO:0018343)
0.5 0.9 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.5 1.8 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.5 1.8 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.5 1.8 GO:0048627 myoblast development(GO:0048627)
0.4 13.6 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.4 6.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.4 5.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.4 2.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.4 1.7 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.4 1.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.4 1.2 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
0.4 6.1 GO:0006600 creatine metabolic process(GO:0006600)
0.4 1.2 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.4 1.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.4 4.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.4 3.5 GO:0032790 ribosome disassembly(GO:0032790)
0.4 1.8 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.4 10.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.3 3.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 1.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 2.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.3 5.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 4.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 4.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 2.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.3 8.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.3 3.5 GO:0097070 ductus arteriosus closure(GO:0097070)
0.3 9.9 GO:0018149 peptide cross-linking(GO:0018149)
0.3 2.3 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.3 1.9 GO:0023021 termination of signal transduction(GO:0023021)
0.3 8.8 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.3 1.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 3.1 GO:0051967 regulation of short-term neuronal synaptic plasticity(GO:0048172) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3 4.8 GO:0002467 germinal center formation(GO:0002467)
0.2 4.7 GO:0005513 detection of calcium ion(GO:0005513)
0.2 2.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 8.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 1.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 8.6 GO:0030199 collagen fibril organization(GO:0030199)
0.2 3.8 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.2 6.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 3.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.2 13.0 GO:0008038 neuron recognition(GO:0008038)
0.2 1.8 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.2 1.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 9.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 1.8 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.2 1.4 GO:0036343 regulation of cell-cell adhesion mediated by integrin(GO:0033632) psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.2 1.7 GO:0045176 apical protein localization(GO:0045176)
0.2 4.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 3.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 6.1 GO:0030261 chromosome condensation(GO:0030261)
0.2 2.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 7.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 11.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.2 3.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.7 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.2 2.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.2 0.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 7.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 3.2 GO:2000178 Rap protein signal transduction(GO:0032486) negative regulation of neural precursor cell proliferation(GO:2000178)
0.2 1.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.2 4.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.2 2.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2 6.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.2 0.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 2.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 41.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 0.6 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 4.1 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.1 0.7 GO:0051597 response to methylmercury(GO:0051597)
0.1 12.4 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 20.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 11.6 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 5.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.0 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 2.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 2.7 GO:0007398 ectoderm development(GO:0007398)
0.1 5.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.3 GO:0015798 myo-inositol transport(GO:0015798)
0.1 2.4 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 4.2 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.8 GO:0042756 drinking behavior(GO:0042756)
0.1 3.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.6 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 8.3 GO:0005977 glycogen metabolic process(GO:0005977)
0.1 2.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.8 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 3.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 3.8 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 3.5 GO:0030317 sperm motility(GO:0030317)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.6 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.1 1.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 3.7 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.1 2.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 5.3 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 2.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 2.6 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 3.3 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 5.2 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 6.6 GO:0007098 centrosome cycle(GO:0007098) centrosome organization(GO:0051297)
0.1 1.5 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 1.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 5.8 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 1.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0001502 cartilage condensation(GO:0001502)
0.0 1.7 GO:0015992 proton transport(GO:0015992)
0.0 3.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.9 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 1.4 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 4.3 GO:0007626 locomotory behavior(GO:0007626)
0.0 2.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.8 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.3 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 4.0 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.3 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 1.5 GO:0031960 response to corticosteroid(GO:0031960)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.6 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 54.4 GO:0097512 cardiac myofibril(GO:0097512)
3.1 12.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
2.7 10.6 GO:0020003 symbiont-containing vacuole(GO:0020003)
2.5 7.6 GO:0005588 collagen type V trimer(GO:0005588)
1.9 9.5 GO:0001652 granular component(GO:0001652)
1.6 8.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
1.4 15.1 GO:0005955 calcineurin complex(GO:0005955)
1.1 4.4 GO:0070695 FHF complex(GO:0070695)
1.1 8.8 GO:0061700 GATOR2 complex(GO:0061700)
1.0 4.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.9 5.6 GO:1990769 proximal neuron projection(GO:1990769)
0.9 4.6 GO:0036398 TCR signalosome(GO:0036398)
0.7 28.4 GO:0042629 mast cell granule(GO:0042629)
0.7 6.6 GO:0070652 HAUS complex(GO:0070652)
0.7 3.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7 2.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.7 2.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.6 1.8 GO:0031933 telomeric heterochromatin(GO:0031933)
0.6 11.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.5 25.8 GO:0031430 M band(GO:0031430)
0.5 3.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.5 3.3 GO:0043196 varicosity(GO:0043196)
0.5 3.3 GO:0032280 symmetric synapse(GO:0032280)
0.5 22.1 GO:0097542 ciliary tip(GO:0097542)
0.4 13.9 GO:0035371 microtubule plus-end(GO:0035371)
0.4 3.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.4 12.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 1.8 GO:0036020 endolysosome membrane(GO:0036020)
0.4 8.8 GO:0044295 axonal growth cone(GO:0044295)
0.3 19.9 GO:0048786 presynaptic active zone(GO:0048786)
0.3 0.6 GO:0097679 other organism cytoplasm(GO:0097679)
0.3 3.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 3.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 3.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 6.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 9.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 26.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 2.0 GO:0005579 membrane attack complex(GO:0005579)
0.2 4.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 4.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 4.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 13.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 3.7 GO:1990909 Wnt signalosome(GO:1990909)
0.2 22.4 GO:0005901 caveola(GO:0005901)
0.2 8.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 5.2 GO:0005859 muscle myosin complex(GO:0005859)
0.2 6.2 GO:0071565 nBAF complex(GO:0071565)
0.2 3.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 12.7 GO:0031594 neuromuscular junction(GO:0031594)
0.2 7.6 GO:0043195 terminal bouton(GO:0043195)
0.2 2.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 1.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 25.8 GO:0008021 synaptic vesicle(GO:0008021)
0.2 5.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 28.3 GO:0030426 growth cone(GO:0030426)
0.1 4.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 4.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 5.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 4.6 GO:0043198 dendritic shaft(GO:0043198)
0.1 3.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.3 GO:0016013 syntrophin complex(GO:0016013)
0.1 3.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.9 GO:0042599 lamellar body(GO:0042599)
0.1 7.2 GO:0005902 microvillus(GO:0005902)
0.1 16.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.1 3.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 13.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 4.2 GO:0016235 aggresome(GO:0016235)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 25.9 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 3.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 6.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 4.5 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 3.2 GO:0016234 inclusion body(GO:0016234)
0.1 17.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 2.3 GO:0045095 keratin filament(GO:0045095)
0.0 9.2 GO:0097060 synaptic membrane(GO:0097060)
0.0 3.8 GO:0034702 ion channel complex(GO:0034702)
0.0 14.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 4.2 GO:0098793 presynapse(GO:0098793)
0.0 8.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 3.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.4 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 3.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.8 GO:0043679 axon terminus(GO:0043679)
0.0 5.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.6 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 3.9 GO:0043235 receptor complex(GO:0043235)
0.0 2.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 2.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 4.9 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.6 GO:0030424 axon(GO:0030424)
0.0 1.1 GO:0098794 postsynapse(GO:0098794)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 5.0 GO:0005743 mitochondrial inner membrane(GO:0005743)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 14.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
3.4 13.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
3.2 9.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
3.2 9.5 GO:0033142 progesterone receptor binding(GO:0033142)
2.6 15.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
2.3 6.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.9 15.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.8 9.1 GO:0070097 delta-catenin binding(GO:0070097)
1.7 51.8 GO:0005212 structural constituent of eye lens(GO:0005212)
1.7 23.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
1.6 23.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
1.5 8.8 GO:0070728 leucine binding(GO:0070728)
1.5 11.6 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.4 9.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.4 4.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.4 4.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
1.2 3.6 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.0 11.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.0 39.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.0 11.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
1.0 7.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.9 3.5 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.9 3.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.8 18.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.8 11.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.8 6.1 GO:0004111 creatine kinase activity(GO:0004111)
0.8 6.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7 12.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.7 15.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.7 2.9 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.7 2.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.6 2.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.6 3.9 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.6 16.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.6 2.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.6 3.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.6 6.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.5 4.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.5 1.6 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.5 9.7 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.5 3.5 GO:0048039 ubiquinone binding(GO:0048039)
0.5 16.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 5.7 GO:0046625 sphingolipid binding(GO:0046625)
0.5 3.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 16.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 1.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 7.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 3.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.4 1.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.4 5.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 10.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 5.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.4 6.1 GO:0031432 titin binding(GO:0031432)
0.4 3.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4 8.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.4 19.7 GO:0030507 spectrin binding(GO:0030507)
0.3 16.6 GO:0050699 WW domain binding(GO:0050699)
0.3 3.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 3.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 4.2 GO:0004707 MAP kinase activity(GO:0004707)
0.3 2.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 17.4 GO:0030552 cAMP binding(GO:0030552)
0.3 4.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 3.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 1.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.3 4.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 3.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 2.5 GO:0016015 morphogen activity(GO:0016015)
0.3 3.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3 7.6 GO:0043394 proteoglycan binding(GO:0043394)
0.3 6.2 GO:0043274 phospholipase binding(GO:0043274)
0.3 5.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 7.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 3.2 GO:0034452 dynactin binding(GO:0034452)
0.2 1.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 3.8 GO:0019841 retinol binding(GO:0019841)
0.2 4.2 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 1.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 1.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 3.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 6.2 GO:0071949 FAD binding(GO:0071949)
0.2 3.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 3.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 6.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 3.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 5.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.8 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.2 15.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 3.7 GO:0048018 receptor agonist activity(GO:0048018)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 2.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 6.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 6.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.6 GO:0048156 tau protein binding(GO:0048156)
0.2 4.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 7.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 0.9 GO:0004905 type I interferon receptor activity(GO:0004905)
0.2 5.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.2 1.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 6.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 1.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 3.6 GO:0031005 filamin binding(GO:0031005)
0.2 0.8 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 2.4 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 5.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 2.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 5.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.8 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.7 GO:1903135 cupric ion binding(GO:1903135)
0.1 2.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 4.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 3.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 6.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.3 GO:0001948 glycoprotein binding(GO:0001948)
0.1 2.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 3.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.3 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 3.7 GO:0070182 protein phosphatase 2A binding(GO:0051721) DNA polymerase binding(GO:0070182)
0.1 27.3 GO:0008017 microtubule binding(GO:0008017)
0.1 1.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 3.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 3.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 12.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.6 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 1.9 GO:0005521 lamin binding(GO:0005521)
0.1 2.6 GO:0005123 death receptor binding(GO:0005123)
0.1 4.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.1 GO:0003680 AT DNA binding(GO:0003680)
0.1 6.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.9 GO:0015248 sterol transporter activity(GO:0015248)
0.1 4.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 5.5 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.1 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 3.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 4.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 2.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 0.7 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.4 GO:0043621 protein self-association(GO:0043621)
0.0 1.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 3.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 7.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 6.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 6.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.6 GO:0004386 helicase activity(GO:0004386)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 25.8 ST GAQ PATHWAY G alpha q Pathway
0.5 14.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.4 17.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.4 13.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 14.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 14.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 17.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 9.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 34.7 PID AP1 PATHWAY AP-1 transcription factor network
0.2 15.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 4.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 4.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.2 3.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 7.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 8.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 6.7 PID INSULIN PATHWAY Insulin Pathway
0.1 9.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 5.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 13.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 18.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 3.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 3.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 4.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 16.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.2 15.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.1 11.8 REACTOME OPSINS Genes involved in Opsins
1.0 34.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.9 31.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.6 13.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 9.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.4 1.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 3.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 20.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.4 15.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 11.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 6.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.3 4.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 4.7 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3 8.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 6.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 10.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 6.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 1.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 7.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 4.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 2.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 10.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 2.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 6.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 3.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.9 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 5.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 5.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 6.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 5.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 3.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 7.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.1 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1 4.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 4.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 6.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 4.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 6.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 16.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 9.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 1.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 6.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 4.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 4.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 4.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 3.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins