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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TLX1_NFIC

Z-value: 4.70

Motif logo

Transcription factors associated with TLX1_NFIC

Gene Symbol Gene ID Gene Info
ENSG00000107807.13 TLX1
ENSG00000141905.19 NFIC

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIChg38_v1_chr19_+_3366549_33666210.426.6e-11Click!
TLX1hg38_v1_chr10_+_101131284_1011313210.244.6e-04Click!

Activity profile of TLX1_NFIC motif

Sorted Z-values of TLX1_NFIC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX1_NFIC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_-_77017042 67.80 ENST00000359645.7
ENST00000397875.7
ENST00000397869.7
ENST00000578193.5
ENST00000578873.5
ENST00000397866.8
ENST00000528160.1
ENST00000527041.1
ENST00000526111.5
ENST00000397865.9
ENST00000382582.7
myelin basic protein
chr16_+_172869 67.61 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
hemoglobin subunit alpha 2
chr8_-_27611325 59.54 ENST00000523500.5
clusterin
chrX_+_103376887 47.32 ENST00000372634.1
brain expressed X-linked 3
chr11_-_111913134 45.07 ENST00000533971.2
ENST00000526180.6
crystallin alpha B
chr8_-_27611424 45.03 ENST00000405140.7
clusterin
chr11_-_111913195 44.43 ENST00000531198.5
ENST00000616970.5
ENST00000527899.6
crystallin alpha B
chrX_+_103376389 42.86 ENST00000372645.3
ENST00000372635.1
brain expressed X-linked 3
chrX_+_103376488 42.63 ENST00000361298.9
brain expressed X-linked 3
chr17_-_15260752 40.64 ENST00000676329.1
ENST00000675551.1
ENST00000644020.1
ENST00000674947.1
peripheral myelin protein 22
chr9_+_136977496 36.60 ENST00000371625.8
ENST00000457950.5
prostaglandin D2 synthase
chr16_+_176659 36.19 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chrX_-_103064164 33.61 ENST00000372728.4
brain expressed X-linked 1
chr1_-_94927079 28.45 ENST00000370206.9
ENST00000394202.8
calponin 3
chr22_-_36817001 26.53 ENST00000406910.6
ENST00000417718.7
parvalbumin
chr8_-_42207667 26.09 ENST00000352041.7
ENST00000679151.1
ENST00000679300.1
plasminogen activator, tissue type
chr16_-_19884828 26.01 ENST00000300571.7
ENST00000570142.5
ENST00000562469.5
G protein-coupled receptor class C group 5 member B
chr8_-_42207557 25.45 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chrX_-_13938378 25.41 ENST00000398361.7
glycoprotein M6B
chr8_+_24914942 24.88 ENST00000433454.3
neurofilament medium
chr14_+_105472930 24.65 ENST00000483017.7
cysteine rich protein 2
chrX_-_13938618 24.01 ENST00000454189.6
glycoprotein M6B
chr3_-_58627596 23.87 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr7_+_116525028 23.22 ENST00000341049.7
caveolin 1
chr22_-_36817510 23.18 ENST00000443735.1
parvalbumin
chr3_-_58627567 21.74 ENST00000649301.1
family with sequence similarity 107 member A
chr5_-_74641419 21.70 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ectodermal-neural cortex 1
chr12_-_55712402 21.12 ENST00000452168.6
integrin subunit alpha 7
chr7_+_116524984 20.44 ENST00000614113.5
ENST00000393470.1
caveolin 1
chr11_-_125592448 20.40 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr14_-_100548098 20.18 ENST00000554356.6
brain enriched guanylate kinase associated
chr2_-_216695540 20.06 ENST00000233813.5
insulin like growth factor binding protein 5
chr10_+_104275126 18.88 ENST00000369707.2
glutathione S-transferase omega 2
chr14_+_85530127 17.52 ENST00000330753.6
fibronectin leucine rich transmembrane protein 2
chr6_+_31982057 17.38 ENST00000428956.7
ENST00000498271.1
complement C4A (Rodgers blood group)
chr21_-_26845402 17.01 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr1_+_109910840 16.25 ENST00000329608.11
ENST00000488198.5
colony stimulating factor 1
chr15_-_68432151 16.13 ENST00000423218.6
ENST00000315757.9
integrin subunit alpha 11
chrX_+_47078380 16.05 ENST00000352078.8
regucalcin
chrX_+_47078434 16.02 ENST00000397180.6
regucalcin
chr1_+_65309517 15.98 ENST00000371069.5
DnaJ heat shock protein family (Hsp40) member C6
chr13_+_112968496 15.97 ENST00000397030.5
MCF.2 cell line derived transforming sequence like
chr8_-_79767843 15.90 ENST00000337919.9
hes related family bHLH transcription factor with YRPW motif 1
chr17_-_44915486 15.07 ENST00000638281.1
ENST00000588316.1
ENST00000588735.3
ENST00000639277.1
ENST00000253408.11
ENST00000435360.8
ENST00000586793.6
ENST00000588037.1
ENST00000592320.6
glial fibrillary acidic protein
chrX_+_47078330 14.81 ENST00000457380.5
regucalcin
chr1_+_109910485 14.57 ENST00000525659.5
colony stimulating factor 1
chr21_-_26843063 14.54 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr9_-_127854636 14.18 ENST00000344849.4
ENST00000373203.9
endoglin
chr2_+_102104563 14.09 ENST00000409589.5
ENST00000409329.5
interleukin 1 receptor type 1
chr8_-_79767462 14.09 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
hes related family bHLH transcription factor with YRPW motif 1
chr22_+_41367269 14.01 ENST00000406644.7
TEF transcription factor, PAR bZIP family member
chr21_-_26843012 13.93 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr5_-_111757175 13.49 ENST00000509025.5
ENST00000257435.12
ENST00000515855.5
neuronal regeneration related protein
chr6_+_32014795 13.19 ENST00000435363.7
ENST00000425700.3
complement C4B (Chido blood group)
chr17_-_28576882 13.05 ENST00000395319.7
ENST00000581807.5
ENST00000226253.9
ENST00000584086.5
ENST00000395321.6
aldolase, fructose-bisphosphate C
chr11_-_117316230 12.78 ENST00000313005.11
ENST00000528053.5
beta-secretase 1
chr3_-_12158901 12.61 ENST00000287814.5
TIMP metallopeptidase inhibitor 4
chr9_+_121268060 12.35 ENST00000373808.8
ENST00000432226.7
ENST00000449733.7
gelsolin
chr20_+_45406162 12.17 ENST00000357275.6
ENST00000372720.7
dysbindin domain containing 2
chr19_+_17215716 11.99 ENST00000593597.1
unconventional SNARE in the ER 1
chr1_+_109910892 11.88 ENST00000369802.7
ENST00000420111.6
colony stimulating factor 1
chr7_-_36985060 11.81 ENST00000396040.6
engulfment and cell motility 1
chr6_-_46954922 11.48 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr11_+_1223053 11.34 ENST00000529681.5
mucin 5B, oligomeric mucus/gel-forming
chr5_-_111757465 11.25 ENST00000446294.6
neuronal regeneration related protein
chr2_-_237414127 11.19 ENST00000472056.5
collagen type VI alpha 3 chain
chr8_-_18683932 10.86 ENST00000615573.4
pleckstrin and Sec7 domain containing 3
chr12_+_119178920 10.83 ENST00000281938.7
heat shock protein family B (small) member 8
chr2_-_237414157 10.60 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
collagen type VI alpha 3 chain
chr1_+_109910986 10.57 ENST00000369801.1
colony stimulating factor 1
chr12_+_57128475 10.53 ENST00000243077.8
ENST00000553277.5
LDL receptor related protein 1
chr12_+_119178953 10.49 ENST00000674542.1
heat shock protein family B (small) member 8
chr1_+_156126525 10.36 ENST00000504687.6
ENST00000473598.6
lamin A/C
chr11_+_1157946 10.32 ENST00000621226.2
mucin 5AC, oligomeric mucus/gel-forming
chr8_-_18684033 10.22 ENST00000614430.3
pleckstrin and Sec7 domain containing 3
chr17_-_78979908 10.14 ENST00000589906.5
ENST00000591778.5
ENST00000262776.8
ENST00000589775.6
ENST00000585407.5
galectin 3 binding protein
chr5_+_150640652 10.03 ENST00000307662.5
synaptopodin
chr3_-_115147277 9.79 ENST00000675478.1
zinc finger and BTB domain containing 20
chr9_-_76906090 9.73 ENST00000376718.8
prune homolog 2 with BCH domain
chr6_+_39792993 9.67 ENST00000538976.5
dishevelled associated activator of morphogenesis 2
chr6_+_39793008 9.62 ENST00000398904.6
dishevelled associated activator of morphogenesis 2
chr2_+_26848424 9.34 ENST00000431402.5
ENST00000614712.4
ENST00000434719.1
dihydropyrimidinase like 5
chr3_-_115147237 9.24 ENST00000357258.8
zinc finger and BTB domain containing 20
chr17_+_29043124 9.18 ENST00000323372.9
pipecolic acid and sarcosine oxidase
chr9_-_76906041 8.89 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr7_+_22727147 8.85 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr8_+_84184875 8.65 ENST00000517638.5
ENST00000522647.1
RALY RNA binding protein like
chr20_+_45406035 8.50 ENST00000372723.7
ENST00000372722.7
dysbindin domain containing 2
chr6_-_53148822 8.46 ENST00000259803.8
glial cells missing transcription factor 1
chr1_-_16018005 8.35 ENST00000406363.2
ENST00000411503.5
ENST00000311890.14
ENST00000487046.1
heat shock protein family B (small) member 7
chr12_+_6535278 8.29 ENST00000396858.5
glyceraldehyde-3-phosphate dehydrogenase
chr8_-_18684093 8.22 ENST00000428502.6
pleckstrin and Sec7 domain containing 3
chr13_+_31945826 7.66 ENST00000647500.1
FRY microtubule binding protein
chr3_+_50267606 7.58 ENST00000618865.4
semaphorin 3B
chr19_+_15673069 7.49 ENST00000550308.6
ENST00000551607.5
cytochrome P450 family 4 subfamily F member 12
chr14_+_85530163 7.49 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chr11_+_75151095 7.49 ENST00000289575.10
ENST00000525650.5
ENST00000454962.6
solute carrier organic anion transporter family member 2B1
chr6_-_30075767 7.28 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr1_-_160523204 7.28 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAM family member 6
chr1_-_31704001 7.27 ENST00000373672.8
collagen type XVI alpha 1 chain
chr20_+_19886506 7.19 ENST00000648440.1
Ras and Rab interactor 2
chrX_-_133985449 7.19 ENST00000631057.2
glypican 3
chr8_-_13276491 7.13 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr5_-_116536458 7.09 ENST00000510263.5
semaphorin 6A
chr19_-_35757009 7.07 ENST00000587965.1
ENST00000004982.6
heat shock protein family B (small) member 6
chr1_-_151372683 6.99 ENST00000458566.5
ENST00000447402.7
ENST00000426705.6
ENST00000368868.10
selenium binding protein 1
chr12_+_53097656 6.96 ENST00000301464.4
insulin like growth factor binding protein 6
chr11_+_46701010 6.94 ENST00000311764.3
zinc finger protein 408
chr11_+_12110569 6.83 ENST00000683283.1
ENST00000256194.8
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr9_+_470291 6.77 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr7_+_86644829 6.74 ENST00000439827.1
ENST00000421579.1
glutamate metabotropic receptor 3
chrX_-_133985574 6.74 ENST00000394299.7
ENST00000370818.8
glypican 3
chr7_+_128830399 6.73 ENST00000325888.13
ENST00000346177.6
filamin C
chr16_-_2214776 6.65 ENST00000333503.8
phosphoglycolate phosphatase
chr1_-_243255320 6.55 ENST00000366544.5
ENST00000366543.5
centrosomal protein 170
chr15_-_65211463 6.26 ENST00000261883.6
cartilage intermediate layer protein
chr19_-_40882226 6.24 ENST00000301146.9
cytochrome P450 family 2 subfamily A member 7
chr12_+_13196718 6.08 ENST00000431267.2
ENST00000542474.5
ENST00000544053.5
ENST00000256951.10
epithelial membrane protein 1
chr3_+_35639589 6.05 ENST00000428373.5
cAMP regulated phosphoprotein 21
chr1_-_39672080 6.04 ENST00000235628.2
5'-nucleotidase, cytosolic IA
chr9_+_99821876 5.93 ENST00000395097.7
nuclear receptor subfamily 4 group A member 3
chr19_+_11541125 5.93 ENST00000587087.5
calponin 1
chr8_-_22131043 5.92 ENST00000312841.9
HR lysine demethylase and nuclear receptor corepressor
chr1_+_203626813 5.89 ENST00000357681.10
ATPase plasma membrane Ca2+ transporting 4
chr8_-_81483226 5.89 ENST00000256104.5
fatty acid binding protein 4
chr11_-_66546021 5.81 ENST00000310442.5
zinc finger DHHC-type containing 24
chr11_+_45146631 5.80 ENST00000534751.3
ENST00000683152.1
PR/SET domain 11
chr15_-_77071032 5.77 ENST00000559494.1
tetraspanin 3
chr1_+_179293760 5.69 ENST00000367619.8
sterol O-acyltransferase 1
chr20_+_24469623 5.67 ENST00000376862.4
synapse differentiation inducing 1
chr6_+_122779707 5.67 ENST00000368444.8
ENST00000356535.4
fatty acid binding protein 7
chr15_-_77071099 5.65 ENST00000267970.9
ENST00000346495.6
ENST00000424443.7
ENST00000561277.5
tetraspanin 3
chr4_-_154491716 5.63 ENST00000339452.2
ENST00000357232.10
dachsous cadherin-related 2
chr10_+_122560679 5.58 ENST00000657942.1
deleted in malignant brain tumors 1
chr8_+_119416427 5.56 ENST00000259526.4
cellular communication network factor 3
chr10_+_122560639 5.52 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr5_-_111757704 5.34 ENST00000379671.7
neuronal regeneration related protein
chr5_-_111757382 5.33 ENST00000453526.6
ENST00000509427.5
neuronal regeneration related protein
chr19_-_11197516 5.32 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KN motif and ankyrin repeat domains 2
chr19_+_4007714 5.30 ENST00000262971.3
protein inhibitor of activated STAT 4
chr5_-_111757643 5.21 ENST00000508870.5
neuronal regeneration related protein
chr17_-_43833137 5.18 ENST00000398389.9
membrane palmitoylated protein 3
chr11_+_68008542 5.18 ENST00000614849.4
aldehyde dehydrogenase 3 family member B1
chr8_-_22131003 5.17 ENST00000381418.9
HR lysine demethylase and nuclear receptor corepressor
chr19_+_42284020 5.16 ENST00000160740.7
capicua transcriptional repressor
chr2_+_66435558 5.15 ENST00000488550.5
Meis homeobox 1
chr22_+_39994926 5.10 ENST00000333407.11
family with sequence similarity 83 member F
chr11_-_35419213 5.08 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
solute carrier family 1 member 2
chr1_+_179293714 5.04 ENST00000540564.5
ENST00000539888.5
sterol O-acyltransferase 1
chr12_+_48119787 4.96 ENST00000551804.5
phosphofructokinase, muscle
chr3_-_50303565 4.94 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
hyaluronidase 1
chr8_+_132919403 4.89 ENST00000519178.5
thyroglobulin
chr3_-_98901656 4.77 ENST00000326840.11
discoidin, CUB and LCCL domain containing 2
chr10_+_122560751 4.74 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr3_+_14947680 4.68 ENST00000435454.5
ENST00000323373.10
nuclear receptor subfamily 2 group C member 2
chr16_+_23755015 4.67 ENST00000300113.3
calcineurin like EF-hand protein 2
chr4_+_143381939 4.67 ENST00000505913.5
GRB2 associated binding protein 1
chr11_+_111977300 4.66 ENST00000615255.1
DIX domain containing 1
chr8_+_97869040 4.65 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
matrilin 2
chr4_-_121381007 4.63 ENST00000394427.3
pyroglutamylated RFamide peptide receptor
chr1_+_203026481 4.58 ENST00000367240.6
PTPRF interacting protein alpha 4
chr9_+_133534697 4.53 ENST00000651351.2
ADAMTS like 2
chr1_-_243255170 4.46 ENST00000366542.6
centrosomal protein 170
chr12_+_108880085 4.44 ENST00000228476.8
ENST00000547768.5
D-amino acid oxidase
chr15_+_40252888 4.42 ENST00000559139.5
ENST00000560669.5
ENST00000542403.3
p21 (RAC1) activated kinase 6
chr11_-_35420050 4.41 ENST00000395753.6
ENST00000395750.6
ENST00000645634.1
solute carrier family 1 member 2
chr17_+_50426242 4.41 ENST00000502667.5
acyl-CoA synthetase family member 2
chr12_+_48119323 4.34 ENST00000551339.6
ENST00000629846.2
ENST00000359794.11
ENST00000548345.5
phosphofructokinase, muscle
chr19_+_49877425 4.33 ENST00000622860.4
TBC1 domain family member 17
chr14_+_92323154 4.32 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr10_-_126388455 4.22 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM metallopeptidase domain 12
chr9_-_127724873 4.11 ENST00000419060.5
peptidyl-tRNA hydrolase 1 homolog
chr3_-_10505508 4.08 ENST00000643662.1
ENST00000397077.6
ENST00000360273.7
ATPase plasma membrane Ca2+ transporting 2
chr19_-_42423100 4.08 ENST00000597001.1
lipase E, hormone sensitive type
chr3_+_9750046 4.07 ENST00000449570.6
ENST00000302008.12
ENST00000383826.9
8-oxoguanine DNA glycosylase
chr18_-_55322215 4.04 ENST00000457482.7
transcription factor 4
chr17_+_50426210 4.04 ENST00000506582.5
ENST00000504392.5
ENST00000300441.9
ENST00000427954.6
acyl-CoA synthetase family member 2
chr6_+_28349907 4.03 ENST00000252211.7
ENST00000341464.9
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr8_+_38386303 4.02 ENST00000519476.6
leucine zipper and EF-hand containing transmembrane protein 2
chr11_+_61950063 4.00 ENST00000534553.5
bestrophin 1
chr2_+_26848093 3.99 ENST00000288699.11
dihydropyrimidinase like 5
chr1_+_78620722 3.97 ENST00000679848.1
interferon induced protein 44 like
chr7_+_76302665 3.89 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
heat shock protein family B (small) member 1
chr7_+_102912983 3.77 ENST00000339431.9
ENST00000249377.4
leucine rich repeat containing 17
chr5_+_114362286 3.75 ENST00000610748.4
ENST00000264773.7
potassium calcium-activated channel subfamily N member 2
chr1_-_93585071 3.74 ENST00000539242.5
BCAR3 adaptor protein, NSP family member
chr11_-_62689523 3.69 ENST00000317449.5
LRRN4 C-terminal like
chr19_-_33225844 3.68 ENST00000253188.8
solute carrier family 7 member 10
chr11_+_28108248 3.53 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
methyltransferase like 15
chr5_-_111757549 3.49 ENST00000419114.6
neuronal regeneration related protein
chr1_+_151540299 3.47 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
tuftelin 1
chr2_+_27771700 3.43 ENST00000379666.7
ENST00000296102.8
mitochondrial ribosomal protein L33
chr8_-_37965953 3.41 ENST00000647937.1
ADRB3-GOT1L1 readthrough
chr9_-_23821809 3.41 ENST00000544538.5
ELAV like RNA binding protein 2
chrX_+_2828808 3.34 ENST00000381163.7
glycogenin 2
chr2_+_66435116 3.31 ENST00000272369.14
ENST00000560281.6
Meis homeobox 1
chr1_-_160070150 3.28 ENST00000644903.1
potassium inwardly rectifying channel subfamily J member 10
chr11_-_35419462 3.27 ENST00000643522.1
solute carrier family 1 member 2
chr3_-_139677718 3.27 ENST00000514703.5
ENST00000511444.5
ENST00000642987.1
ENST00000296202.11
ENST00000509291.5
ENST00000413939.6
ENST00000643695.2
ENST00000339837.9
ENST00000512391.5
ENST00000645507.1
nicotinamide nucleotide adenylyltransferase 3
chr5_+_170782682 3.24 ENST00000518525.5
ENST00000518122.5
gamma-aminobutyric acid type A receptor subunit pi

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
20.9 104.6 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
13.6 67.8 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
13.3 53.3 GO:1902228 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
11.7 46.9 GO:1903631 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
10.9 43.7 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
10.0 30.0 GO:0061027 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
6.7 20.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
6.2 24.9 GO:0033693 neurofilament bundle assembly(GO:0033693)
5.3 89.5 GO:0007021 tubulin complex assembly(GO:0007021)
4.7 14.2 GO:0001300 chronological cell aging(GO:0001300)
4.7 14.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
4.1 49.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
3.5 10.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
3.5 13.9 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
3.1 21.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
3.0 9.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
2.8 8.5 GO:0060018 astrocyte fate commitment(GO:0060018)
2.8 30.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
2.8 24.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
2.7 5.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
2.6 7.9 GO:0060005 vestibular reflex(GO:0060005)
2.5 45.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
2.5 17.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
2.4 49.5 GO:0032060 bleb assembly(GO:0032060)
2.3 9.2 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
2.3 6.8 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
2.3 20.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
2.2 8.9 GO:2000366 response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
2.1 10.7 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.1 18.9 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
2.1 8.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.9 7.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
1.9 36.0 GO:0015671 oxygen transport(GO:0015671)
1.9 7.5 GO:0003095 pressure natriuresis(GO:0003095)
1.9 9.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
1.8 37.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.8 15.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.7 51.5 GO:0031639 plasminogen activation(GO:0031639)
1.7 6.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.6 26.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
1.6 28.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.5 4.4 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-amino acid metabolic process(GO:0046416)
1.4 5.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
1.3 16.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.3 4.0 GO:1901205 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
1.2 4.9 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.2 7.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
1.2 6.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
1.1 11.5 GO:0043129 surfactant homeostasis(GO:0043129)
1.0 10.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0 7.2 GO:0045007 depurination(GO:0045007)
1.0 28.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.0 15.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.0 3.9 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.9 16.1 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.9 121.2 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.9 10.0 GO:0099563 modification of synaptic structure(GO:0099563)
0.8 3.1 GO:0051182 coenzyme transport(GO:0051182)
0.7 12.6 GO:0042940 D-amino acid transport(GO:0042940)
0.7 13.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.7 4.9 GO:0015705 iodide transport(GO:0015705)
0.6 1.9 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.6 5.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.6 2.5 GO:0061107 seminal vesicle development(GO:0061107)
0.6 1.9 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.6 4.4 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.6 3.8 GO:0048539 bone marrow development(GO:0048539)
0.6 4.3 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.6 3.1 GO:0090131 mesenchyme migration(GO:0090131)
0.6 9.0 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.6 5.7 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.5 1.6 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.5 11.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.5 1.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.5 5.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.5 1.4 GO:0061074 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.4 1.3 GO:1902462 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.4 8.5 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.4 5.6 GO:0051873 innate immune response in mucosa(GO:0002227) killing by host of symbiont cells(GO:0051873)
0.4 6.0 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.4 5.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.4 6.0 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
0.4 2.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.4 6.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 3.5 GO:0070475 rRNA base methylation(GO:0070475)
0.4 1.9 GO:0002933 lipid hydroxylation(GO:0002933)
0.4 7.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.4 7.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.4 2.5 GO:0048241 epinephrine transport(GO:0048241)
0.4 21.7 GO:0016266 O-glycan processing(GO:0016266)
0.4 19.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 5.9 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.3 1.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 3.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.3 4.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 4.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.3 24.0 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.3 5.7 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.3 4.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.3 7.3 GO:0033622 integrin activation(GO:0033622)
0.3 21.8 GO:0030574 collagen catabolic process(GO:0030574)
0.3 12.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.3 1.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 2.0 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.3 3.1 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 4.7 GO:0008347 glial cell migration(GO:0008347)
0.3 7.1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.3 3.0 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.3 4.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 4.3 GO:0097186 amelogenesis(GO:0097186)
0.3 11.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.2 2.7 GO:0051964 netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.2 2.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.2 0.5 GO:0071072 positive regulation of glomerular filtration(GO:0003104) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.2 0.7 GO:1904640 response to methionine(GO:1904640)
0.2 0.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 1.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 2.4 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.2 5.7 GO:0060134 prepulse inhibition(GO:0060134)
0.2 1.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.6 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.2 2.9 GO:0099612 protein localization to axon(GO:0099612)
0.2 7.6 GO:0050919 negative chemotaxis(GO:0050919)
0.2 1.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.2 1.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 1.3 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.2 2.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.4 GO:0035712 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.2 2.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.5 GO:0099557 trans-synaptic signaling by trans-synaptic complex(GO:0099545) trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.2 2.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 5.0 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.1 1.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 5.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 4.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 1.8 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.8 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1 6.7 GO:0048747 muscle fiber development(GO:0048747)
0.1 12.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 12.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 3.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 5.2 GO:0046710 GDP metabolic process(GO:0046710)
0.1 10.1 GO:0006968 cellular defense response(GO:0006968)
0.1 1.8 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 4.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 3.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 41.3 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.1 3.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 43.7 GO:0001558 regulation of cell growth(GO:0001558)
0.1 0.6 GO:0060282 negative regulation of cardiac muscle contraction(GO:0055118) positive regulation of oocyte development(GO:0060282)
0.1 0.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.5 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
0.1 3.5 GO:0014047 glutamate secretion(GO:0014047)
0.1 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.0 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 4.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.8 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 1.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 3.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 3.5 GO:0030282 bone mineralization(GO:0030282)
0.0 0.6 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 8.6 GO:0007411 axon guidance(GO:0007411)
0.0 0.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 8.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 8.0 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 2.5 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 1.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 7.5 GO:0048511 rhythmic process(GO:0048511)
0.0 2.5 GO:0030449 regulation of complement activation(GO:0030449)
0.0 2.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.3 67.8 GO:0033269 internode region of axon(GO:0033269)
9.0 36.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
8.9 53.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
8.6 129.5 GO:0097418 neurofibrillary tangle(GO:0097418)
7.2 21.7 GO:0070701 mucus layer(GO:0070701)
5.6 89.5 GO:0097512 cardiac myofibril(GO:0097512)
4.7 14.2 GO:0072563 endothelial microparticle(GO:0072563)
4.3 12.8 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
4.0 16.1 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
2.6 43.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.3 27.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
1.7 21.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.5 9.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.3 40.6 GO:0043218 compact myelin(GO:0043218)
1.3 6.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.9 8.3 GO:0097452 GAIT complex(GO:0097452)
0.9 7.3 GO:0005593 FACIT collagen trimer(GO:0005593)
0.8 2.5 GO:0097180 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.8 11.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.8 15.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.8 12.4 GO:0030478 actin cap(GO:0030478)
0.7 7.3 GO:0005638 lamin filament(GO:0005638)
0.7 2.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.5 10.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.5 6.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 49.7 GO:0043195 terminal bouton(GO:0043195)
0.5 2.9 GO:1990769 proximal neuron projection(GO:1990769)
0.5 0.5 GO:0042643 actomyosin, actin portion(GO:0042643)
0.5 0.9 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.5 8.2 GO:0042629 mast cell granule(GO:0042629)
0.4 13.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 49.4 GO:0005604 basement membrane(GO:0005604)
0.4 16.3 GO:0008305 integrin complex(GO:0008305)
0.3 21.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 22.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 27.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 4.3 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.3 43.0 GO:0032587 ruffle membrane(GO:0032587)
0.2 13.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 32.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 8.9 GO:0030673 axolemma(GO:0030673)
0.2 16.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 9.5 GO:0016235 aggresome(GO:0016235)
0.2 6.7 GO:0043034 costamere(GO:0043034)
0.2 1.3 GO:0060091 kinocilium(GO:0060091)
0.2 3.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 16.1 GO:0005882 intermediate filament(GO:0005882)
0.1 70.6 GO:0045177 apical part of cell(GO:0045177)
0.1 4.0 GO:0097228 sperm principal piece(GO:0097228)
0.1 10.0 GO:0043204 perikaryon(GO:0043204)
0.1 4.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.9 GO:0097433 dense body(GO:0097433)
0.1 9.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 3.8 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 33.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 50.7 GO:0030424 axon(GO:0030424)
0.1 10.0 GO:0005811 lipid particle(GO:0005811)
0.1 7.6 GO:0034707 chloride channel complex(GO:0034707)
0.1 4.1 GO:0043198 dendritic shaft(GO:0043198)
0.1 24.4 GO:0005938 cell cortex(GO:0005938)
0.1 1.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 50.2 GO:0016607 nuclear speck(GO:0016607)
0.1 24.4 GO:0045121 membrane raft(GO:0045121)
0.1 2.6 GO:0008180 COP9 signalosome(GO:0008180)
0.1 3.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 11.4 GO:0001650 fibrillar center(GO:0001650)
0.1 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 2.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 2.0 GO:0005903 brush border(GO:0005903)
0.1 8.9 GO:0030425 dendrite(GO:0030425)
0.1 6.0 GO:0055037 recycling endosome(GO:0055037)
0.0 1.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.5 GO:0005771 multivesicular body(GO:0005771)
0.0 3.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 6.3 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 4.6 GO:0005814 centriole(GO:0005814)
0.0 1.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
33.2 132.8 GO:0005163 nerve growth factor receptor binding(GO:0005163)
11.7 46.9 GO:0004341 gluconolactonase activity(GO:0004341)
10.9 43.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
10.7 53.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
9.1 36.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
7.5 30.0 GO:0035939 microsatellite binding(GO:0035939)
5.6 67.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
5.3 15.8 GO:0035375 zymogen binding(GO:0035375)
4.6 13.9 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
4.5 104.3 GO:0051787 misfolded protein binding(GO:0051787)
3.8 18.9 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
3.6 10.7 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
3.5 14.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
3.5 10.5 GO:0030226 apolipoprotein receptor activity(GO:0030226)
3.3 99.5 GO:0005212 structural constituent of eye lens(GO:0005212)
3.2 12.8 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
2.8 8.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
2.5 17.4 GO:0001849 complement component C1q binding(GO:0001849)
2.4 36.0 GO:0005344 oxygen transporter activity(GO:0005344)
2.3 27.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
2.2 6.7 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
2.2 6.6 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
2.0 16.1 GO:0038064 collagen receptor activity(GO:0038064)
1.8 9.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.8 14.2 GO:0005534 galactose binding(GO:0005534)
1.6 4.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.6 4.8 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
1.5 4.6 GO:0005055 laminin receptor activity(GO:0005055)
1.4 4.3 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
1.4 4.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
1.3 4.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
1.3 3.9 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
1.3 7.7 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
1.2 13.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.2 9.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.1 25.0 GO:0045499 chemorepellent activity(GO:0045499)
1.0 6.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.0 28.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.9 5.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.9 12.4 GO:0045159 myosin II binding(GO:0045159)
0.9 3.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.9 4.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.8 28.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.8 2.5 GO:0008431 vitamin E binding(GO:0008431)
0.8 4.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.8 2.4 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.7 4.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.7 8.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.7 25.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.7 6.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7 4.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.6 1.9 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.6 8.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.6 6.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.6 2.5 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.6 1.8 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.6 11.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.6 7.0 GO:0008430 selenium binding(GO:0008430)
0.5 8.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.5 13.2 GO:0001848 complement binding(GO:0001848)
0.5 10.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 7.6 GO:0038191 neuropilin binding(GO:0038191)
0.4 3.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.4 6.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 6.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.4 51.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.4 11.3 GO:0071949 FAD binding(GO:0071949)
0.4 9.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 1.9 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4 8.4 GO:0031005 filamin binding(GO:0031005)
0.4 1.1 GO:0015265 urea channel activity(GO:0015265)
0.4 3.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 48.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 1.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 5.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 4.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.3 6.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 3.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 5.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 2.5 GO:0032190 acrosin binding(GO:0032190)
0.3 0.8 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 28.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.3 1.3 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.3 1.0 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 12.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 1.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 21.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 6.7 GO:0030506 ankyrin binding(GO:0030506)
0.2 2.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 2.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 1.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 4.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 7.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.7 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 3.1 GO:0015295 solute:proton symporter activity(GO:0015295)
0.1 0.9 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 10.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 5.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 16.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 3.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 5.7 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 3.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 13.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.5 GO:0048407 superoxide-generating NADPH oxidase activator activity(GO:0016176) platelet-derived growth factor binding(GO:0048407)
0.1 9.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 6.8 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 15.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 7.4 GO:0019838 growth factor binding(GO:0019838)
0.1 2.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 12.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 22.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.5 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 6.2 GO:0008168 methyltransferase activity(GO:0008168)
0.0 1.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)
0.0 1.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 8.9 ST STAT3 PATHWAY STAT3 Pathway
1.3 50.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.3 57.7 PID ALK1 PATHWAY ALK1 signaling events
1.2 58.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.9 33.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.9 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.8 10.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.7 31.6 NABA COLLAGENS Genes encoding collagen proteins
0.7 90.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.5 37.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.4 22.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.4 5.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 23.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.4 12.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.3 3.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 33.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.3 5.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 55.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 57.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 10.6 ST GA12 PATHWAY G alpha 12 Pathway
0.2 61.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 18.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 5.6 PID SHP2 PATHWAY SHP2 signaling
0.1 7.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 5.3 PID IFNG PATHWAY IFN-gamma pathway
0.1 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 14.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 7.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 4.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.6 PID RHOA PATHWAY RhoA signaling pathway
0.1 6.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 53.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.1 27.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.9 21.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.9 17.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.7 106.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.6 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.5 4.7 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.5 25.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.5 13.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 15.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 28.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 8.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 13.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 6.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.4 5.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.4 6.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 29.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 6.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 4.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 5.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.3 11.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3 4.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 40.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.2 16.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 2.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 4.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 19.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 9.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 4.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 4.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 8.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 2.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 6.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 12.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 6.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 4.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 11.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 4.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 4.2 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.2 2.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 7.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 6.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 9.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 4.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 3.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation