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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UAAUGCU

Z-value: 0.24

Motif logo

logo of

miRNA associated with seed UAAUGCU

NamemiRBASE accession
hsa-miR-155-5p
MIMAT0000646

Activity profile of UAAUGCU motif

Sorted Z-values of UAAUGCU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UAAUGCU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_50190821 5.41 ENST00000303004.5
CEBPB
CCAAT enhancer binding protein beta
chr16_-_10580577 3.62 ENST00000359543.8
EMP2
epithelial membrane protein 2
chr12_-_14885845 3.31 ENST00000539261.6
ENST00000228938.5
MGP
matrix Gla protein
chr20_-_40689228 3.12 ENST00000373313.3
MAFB
MAF bZIP transcription factor B
chrX_-_74614612 2.92 ENST00000349225.2
ENST00000332687.11
RLIM
ring finger protein, LIM domain interacting
chr7_-_140176970 2.90 ENST00000397560.7
KDM7A
lysine demethylase 7A
chr2_+_28392802 2.79 ENST00000379619.5
ENST00000264716.9
FOSL2
FOS like 2, AP-1 transcription factor subunit
chr10_-_118754956 2.37 ENST00000369151.8
CACUL1
CDK2 associated cullin domain 1
chr3_-_123884290 2.27 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
MYLK
myosin light chain kinase
chr2_+_66435558 2.08 ENST00000488550.5
MEIS1
Meis homeobox 1
chr11_+_114059702 2.02 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
ZBTB16
zinc finger and BTB domain containing 16
chr15_+_96330691 2.02 ENST00000394166.8
NR2F2
nuclear receptor subfamily 2 group F member 2
chr12_+_2052977 2.01 ENST00000399634.6
ENST00000406454.8
ENST00000327702.12
ENST00000347598.9
ENST00000399603.6
ENST00000399641.6
ENST00000399655.6
ENST00000335762.10
ENST00000682835.1
CACNA1C
calcium voltage-gated channel subunit alpha1 C
chr3_-_21751189 1.86 ENST00000281523.8
ZNF385D
zinc finger protein 385D
chr1_+_113979391 1.82 ENST00000393300.6
ENST00000369551.5
OLFML3
olfactomedin like 3
chr11_-_64878612 1.74 ENST00000320631.8
EHD1
EH domain containing 1
chr14_+_75278820 1.69 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
chr1_-_202808406 1.67 ENST00000650569.1
ENST00000367265.9
ENST00000649770.1
KDM5B
lysine demethylase 5B
chr21_+_29298890 1.67 ENST00000286800.8
BACH1
BTB domain and CNC homolog 1
chr11_+_119206298 1.66 ENST00000634586.1
ENST00000634840.1
ENST00000264033.6
ENST00000637974.1
CBL
Cbl proto-oncogene
chr1_-_229434086 1.59 ENST00000366684.7
ENST00000684723.1
ENST00000366683.4
ACTA1
actin alpha 1, skeletal muscle
chrX_+_65488735 1.57 ENST00000338957.4
ZC3H12B
zinc finger CCCH-type containing 12B
chr18_+_70288991 1.55 ENST00000397942.4
SOCS6
suppressor of cytokine signaling 6
chr6_+_7107941 1.51 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
RREB1
ras responsive element binding protein 1
chr13_+_112067143 1.46 ENST00000330949.3
SOX1
SRY-box transcription factor 1
chr9_-_16870662 1.41 ENST00000380672.9
BNC2
basonuclin 2
chrX_-_54357993 1.39 ENST00000375169.7
ENST00000354646.6
WNK3
WNK lysine deficient protein kinase 3
chr6_-_6320642 1.39 ENST00000451619.1
ENST00000264870.8
F13A1
coagulation factor XIII A chain
chr12_+_96194365 1.37 ENST00000228741.8
ENST00000547249.1
ELK3
ETS transcription factor ELK3
chr8_+_55102012 1.36 ENST00000327381.7
XKR4
XK related 4
chr4_+_7043315 1.34 ENST00000310074.8
ENST00000512388.1
TADA2B
transcriptional adaptor 2B
chr3_-_142000353 1.33 ENST00000499676.5
TFDP2
transcription factor Dp-2
chr12_+_104064520 1.32 ENST00000229330.9
HCFC2
host cell factor C2
chr5_-_161546708 1.32 ENST00000393959.6
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr2_+_46297397 1.32 ENST00000263734.5
EPAS1
endothelial PAS domain protein 1
chr21_+_36699100 1.29 ENST00000290399.11
SIM2
SIM bHLH transcription factor 2
chr17_-_13601901 1.28 ENST00000284110.2
HS3ST3A1
heparan sulfate-glucosamine 3-sulfotransferase 3A1
chr1_-_9943314 1.28 ENST00000377223.6
ENST00000377213.1
LZIC
leucine zipper and CTNNBIP1 domain containing
chr18_-_47930630 1.27 ENST00000262160.11
SMAD2
SMAD family member 2
chr7_+_107168961 1.25 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HBP1
HMG-box transcription factor 1
chr6_+_135181323 1.24 ENST00000367814.8
MYB
MYB proto-oncogene, transcription factor
chr8_-_56211257 1.24 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1
PLAG1 zinc finger
chr2_-_64144411 1.23 ENST00000358912.5
PELI1
pellino E3 ubiquitin protein ligase 1
chr14_+_102592611 1.16 ENST00000262241.7
RCOR1
REST corepressor 1
chr19_+_1941118 1.13 ENST00000255641.13
CSNK1G2
casein kinase 1 gamma 2
chrX_+_107825755 1.08 ENST00000451923.1
ENST00000262843.11
MID2
midline 2
chr2_-_43226594 1.05 ENST00000282388.4
ZFP36L2
ZFP36 ring finger protein like 2
chr12_+_68610858 1.04 ENST00000393436.9
ENST00000425247.6
ENST00000250559.14
ENST00000489473.6
ENST00000422358.6
ENST00000541167.5
ENST00000538283.5
ENST00000341355.9
ENST00000537460.5
ENST00000450214.6
ENST00000545270.5
RAP1B
RAP1B, member of RAS oncogene family
chr14_-_29927801 1.04 ENST00000331968.11
PRKD1
protein kinase D1
chr8_+_40153475 0.98 ENST00000315792.5
TCIM
transcriptional and immune response regulator
chr4_+_38664189 0.95 ENST00000514033.1
ENST00000261438.10
KLF3
Kruppel like factor 3
chr15_-_61229297 0.94 ENST00000335670.11
RORA
RAR related orphan receptor A
chr7_-_113919000 0.93 ENST00000284601.4
PPP1R3A
protein phosphatase 1 regulatory subunit 3A
chr8_-_104588998 0.93 ENST00000424843.6
LRP12
LDL receptor related protein 12
chr2_-_152099023 0.91 ENST00000201943.10
ENST00000427385.6
ENST00000539935.7
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr3_-_50567646 0.89 ENST00000426034.5
ENST00000441239.5
C3orf18
chromosome 3 open reading frame 18
chr10_+_8054668 0.88 ENST00000379328.9
GATA3
GATA binding protein 3
chr19_-_14518383 0.86 ENST00000254322.3
ENST00000595139.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr22_+_36913620 0.85 ENST00000403662.8
ENST00000262825.9
CSF2RB
colony stimulating factor 2 receptor subunit beta
chrX_+_137566119 0.81 ENST00000287538.10
ZIC3
Zic family member 3
chr11_-_128522264 0.80 ENST00000531611.5
ETS1
ETS proto-oncogene 1, transcription factor
chr11_+_47257953 0.78 ENST00000437276.1
ENST00000436029.5
ENST00000467728.5
ENST00000441012.7
ENST00000405853.7
NR1H3
nuclear receptor subfamily 1 group H member 3
chr8_-_115668966 0.77 ENST00000395715.8
TRPS1
transcriptional repressor GATA binding 1
chr7_+_155458129 0.77 ENST00000297375.4
EN2
engrailed homeobox 2
chr10_-_103855406 0.76 ENST00000355946.6
ENST00000369774.8
SH3PXD2A
SH3 and PX domains 2A
chr10_-_110304894 0.75 ENST00000369603.10
SMNDC1
survival motor neuron domain containing 1
chr9_-_23821275 0.73 ENST00000380110.8
ELAVL2
ELAV like RNA binding protein 2
chr3_-_160565560 0.71 ENST00000334256.9
ENST00000676866.1
ENST00000469804.1
KPNA4
karyopherin subunit alpha 4
chr1_+_59814939 0.71 ENST00000371208.5
HOOK1
hook microtubule tethering protein 1
chr5_-_95961830 0.69 ENST00000513343.1
ENST00000237853.9
ELL2
elongation factor for RNA polymerase II 2
chr3_-_190322434 0.69 ENST00000295522.4
CLDN1
claudin 1
chr3_+_30606574 0.69 ENST00000295754.10
ENST00000359013.4
TGFBR2
transforming growth factor beta receptor 2
chr7_+_4682252 0.68 ENST00000328914.5
FOXK1
forkhead box K1
chr6_+_15246054 0.68 ENST00000341776.7
JARID2
jumonji and AT-rich interaction domain containing 2
chr7_-_155812454 0.67 ENST00000297261.7
SHH
sonic hedgehog signaling molecule
chr10_-_118342292 0.67 ENST00000369172.8
ENST00000369183.9
FAM204A
family with sequence similarity 204 member A
chr8_-_133102477 0.66 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
SLA
Src like adaptor
chr6_+_41072939 0.66 ENST00000341376.11
ENST00000353205.5
NFYA
nuclear transcription factor Y subunit alpha
chr14_+_75069577 0.66 ENST00000238686.8
ZC2HC1C
zinc finger C2HC-type containing 1C
chr5_-_9546066 0.63 ENST00000382496.10
ENST00000652226.1
SEMA5A
semaphorin 5A
chr3_-_113746218 0.62 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr5_+_136132772 0.62 ENST00000545279.6
ENST00000507118.5
ENST00000511116.5
ENST00000545620.5
ENST00000509297.6
SMAD5
SMAD family member 5
chr16_-_8868343 0.59 ENST00000562843.5
ENST00000561530.5
ENST00000396593.6
CARHSP1
calcium regulated heat stable protein 1
chr1_+_61742418 0.59 ENST00000316485.11
ENST00000371158.6
ENST00000642238.2
ENST00000613764.4
PATJ
PATJ crumbs cell polarity complex component
chr2_+_69829630 0.58 ENST00000282570.4
GMCL1
germ cell-less 1, spermatogenesis associated
chr7_-_44885446 0.57 ENST00000395699.5
PURB
purine rich element binding protein B
chr1_-_157138388 0.57 ENST00000368192.9
ETV3
ETS variant transcription factor 3
chrX_+_49922605 0.57 ENST00000376088.7
CLCN5
chloride voltage-gated channel 5
chr12_+_71839707 0.57 ENST00000482439.6
ENST00000550746.5
ENST00000491063.5
ENST00000319106.12
ENST00000485960.7
TBC1D15
TBC1 domain family member 15
chr11_+_67119245 0.57 ENST00000529006.7
ENST00000398645.6
KDM2A
lysine demethylase 2A
chr15_+_92393841 0.55 ENST00000268164.8
ENST00000539113.5
ENST00000555434.1
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr1_+_213987929 0.55 ENST00000498508.6
ENST00000366958.9
PROX1
prospero homeobox 1
chr17_-_67245165 0.54 ENST00000580168.5
ENST00000358691.10
HELZ
helicase with zinc finger
chr8_-_64798725 0.53 ENST00000310193.4
CYP7B1
cytochrome P450 family 7 subfamily B member 1
chr15_-_34336749 0.52 ENST00000397707.6
ENST00000560611.5
SLC12A6
solute carrier family 12 member 6
chr16_-_11256192 0.51 ENST00000644787.1
ENST00000332029.4
SOCS1
suppressor of cytokine signaling 1
chr4_+_168497066 0.51 ENST00000261509.10
PALLD
palladin, cytoskeletal associated protein
chrX_+_129982610 0.50 ENST00000218147.11
ENST00000540052.6
BCORL1
BCL6 corepressor like 1
chr17_-_64130125 0.50 ENST00000680433.1
ENST00000433197.4
ERN1
endoplasmic reticulum to nucleus signaling 1
chr8_-_66613208 0.50 ENST00000522677.8
MYBL1
MYB proto-oncogene like 1
chr7_-_82443766 0.49 ENST00000356860.8
CACNA2D1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr3_-_122514876 0.48 ENST00000493510.1
ENST00000476916.5
ENST00000344337.11
ENST00000465882.5
KPNA1
karyopherin subunit alpha 1
chr16_-_48610150 0.48 ENST00000262384.4
N4BP1
NEDD4 binding protein 1
chr5_+_157180816 0.46 ENST00000422843.8
ITK
IL2 inducible T cell kinase
chr2_-_23927107 0.46 ENST00000238789.10
ATAD2B
ATPase family AAA domain containing 2B
chr6_+_148747016 0.46 ENST00000367463.5
UST
uronyl 2-sulfotransferase
chrX_+_123859976 0.45 ENST00000371199.8
XIAP
X-linked inhibitor of apoptosis
chr2_+_5692357 0.45 ENST00000322002.5
SOX11
SRY-box transcription factor 11
chr5_+_14581766 0.44 ENST00000274217.4
OTULINL
OTU deubiquitinase with linear linkage specificity like
chr6_+_108559742 0.44 ENST00000343882.10
FOXO3
forkhead box O3
chr1_-_204151884 0.43 ENST00000367201.7
ETNK2
ethanolamine kinase 2
chr2_-_64653906 0.42 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr11_-_65662780 0.42 ENST00000534283.1
ENST00000527749.5
ENST00000533187.5
ENST00000525693.5
ENST00000534558.5
ENST00000532879.5
ENST00000406246.8
ENST00000532999.5
RELA
RELA proto-oncogene, NF-kB subunit
chr7_-_130440848 0.42 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
CEP41
centrosomal protein 41
chr12_-_8612850 0.41 ENST00000229335.11
ENST00000537228.5
AICDA
activation induced cytidine deaminase
chr10_+_99659430 0.41 ENST00000370489.5
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr10_+_80454148 0.41 ENST00000429989.7
TSPAN14
tetraspanin 14
chr2_+_47783082 0.41 ENST00000614496.4
ENST00000622629.4
ENST00000234420.11
ENST00000616033.4
ENST00000673637.1
MSH6
mutS homolog 6
chr1_+_32817645 0.40 ENST00000526230.1
ENST00000373475.10
ENST00000531256.1
ENST00000482212.1
S100PBP
S100P binding protein
chr11_+_63839086 0.39 ENST00000350490.11
ENST00000402010.8
MARK2
microtubule affinity regulating kinase 2
chr1_-_21783189 0.39 ENST00000400301.5
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr16_+_30699155 0.38 ENST00000262518.9
SRCAP
Snf2 related CREBBP activator protein
chrX_-_130110679 0.37 ENST00000335997.11
ELF4
E74 like ETS transcription factor 4
chr11_-_83071819 0.37 ENST00000524635.1
ENST00000526205.5
ENST00000533486.5
ENST00000533276.6
ENST00000527633.6
RAB30
RAB30, member RAS oncogene family
chr12_-_66678934 0.36 ENST00000545666.5
ENST00000398016.7
ENST00000359742.9
ENST00000538211.5
GRIP1
glutamate receptor interacting protein 1
chr10_+_93993897 0.35 ENST00000371380.8
PLCE1
phospholipase C epsilon 1
chr10_+_67884646 0.35 ENST00000212015.11
SIRT1
sirtuin 1
chr3_-_108090971 0.34 ENST00000355354.13
ENST00000361309.6
CD47
CD47 molecule
chr12_+_4909895 0.34 ENST00000638821.1
ENST00000382545.5
ENSG00000256654.4
KCNA1
novel transcript, sense overlapping KCNA1
potassium voltage-gated channel subfamily A member 1
chr19_+_4402615 0.34 ENST00000301280.10
CHAF1A
chromatin assembly factor 1 subunit A
chr10_+_102776237 0.33 ENST00000369889.5
WBP1L
WW domain binding protein 1 like
chr9_+_88388356 0.31 ENST00000375859.4
SPIN1
spindlin 1
chr8_-_86743626 0.31 ENST00000320005.6
CNGB3
cyclic nucleotide gated channel subunit beta 3
chr1_+_101237009 0.31 ENST00000305352.7
S1PR1
sphingosine-1-phosphate receptor 1
chr21_-_39313610 0.30 ENST00000342449.8
ENST00000341322.4
BRWD1
bromodomain and WD repeat domain containing 1
chr3_-_120094436 0.30 ENST00000264235.13
ENST00000677034.1
GSK3B
glycogen synthase kinase 3 beta
chr15_+_89088417 0.29 ENST00000569550.5
ENST00000565066.5
ENST00000565973.5
ENST00000352732.10
ABHD2
abhydrolase domain containing 2, acylglycerol lipase
chr4_-_148444674 0.28 ENST00000344721.8
NR3C2
nuclear receptor subfamily 3 group C member 2
chr12_+_20368495 0.28 ENST00000359062.4
PDE3A
phosphodiesterase 3A
chr10_+_96832252 0.28 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
LCOR
ligand dependent nuclear receptor corepressor
chr20_+_33490073 0.28 ENST00000342704.11
ENST00000375279.6
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr16_+_69565958 0.28 ENST00000349945.7
ENST00000354436.6
NFAT5
nuclear factor of activated T cells 5
chr1_-_111739253 0.27 ENST00000527621.1
ENST00000534365.1
ENST00000357260.6
INKA2
inka box actin regulator 2
chr2_-_101308681 0.27 ENST00000295317.4
RNF149
ring finger protein 149
chr1_+_154405193 0.26 ENST00000622330.4
ENST00000344086.8
IL6R
interleukin 6 receptor
chr7_+_139231225 0.26 ENST00000473989.8
UBN2
ubinuclein 2
chr11_+_47980538 0.26 ENST00000613246.4
ENST00000418331.7
ENST00000615445.4
ENST00000440289.6
PTPRJ
protein tyrosine phosphatase receptor type J
chrX_+_16946650 0.26 ENST00000357277.8
REPS2
RALBP1 associated Eps domain containing 2
chr1_-_77979054 0.26 ENST00000370768.7
ENST00000370767.5
ENST00000421641.1
FUBP1
far upstream element binding protein 1
chr5_+_112976757 0.25 ENST00000389063.3
DCP2
decapping mRNA 2
chr2_+_227472132 0.25 ENST00000409979.6
ENST00000310078.13
AGFG1
ArfGAP with FG repeats 1
chr8_-_23682889 0.24 ENST00000523261.1
ENST00000380871.5
NKX3-1
NK3 homeobox 1
chr7_+_43112593 0.24 ENST00000453890.5
ENST00000395891.7
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr17_+_4710622 0.24 ENST00000574954.5
ENST00000269260.7
ENST00000346341.6
ENST00000572457.5
ENST00000381488.10
ENST00000412477.7
ENST00000571428.5
ENST00000575877.5
ARRB2
arrestin beta 2
chr3_+_57556244 0.23 ENST00000311180.9
ENST00000487257.1
PDE12
phosphodiesterase 12
chr15_-_58749569 0.22 ENST00000402627.5
ENST00000559053.1
ENST00000260408.8
ENST00000561288.1
ENST00000461408.2
ENST00000439637.5
ENST00000558004.1
ADAM10
ADAM metallopeptidase domain 10
chr17_-_32877106 0.22 ENST00000318217.10
ENST00000579584.5
ENST00000583621.1
MYO1D
myosin ID
chr9_+_79571767 0.22 ENST00000376544.7
TLE4
TLE family member 4, transcriptional corepressor
chr14_-_31026363 0.22 ENST00000357479.10
ENST00000355683.9
STRN3
striatin 3
chr17_-_714709 0.21 ENST00000401468.7
ENST00000575100.2
ENST00000680069.1
ENST00000681902.1
ENST00000576019.6
ENST00000571456.2
ENST00000679361.1
ENST00000680241.1
ENST00000681917.1
ENST00000681133.1
ENST00000437048.7
ENST00000680128.1
ENST00000681154.1
ENST00000679961.1
ENST00000680970.1
ENST00000681295.1
ENST00000574029.6
ENST00000681317.1
ENST00000571805.6
ENST00000291074.10
VPS53
VPS53 subunit of GARP complex
chr6_+_36885944 0.21 ENST00000480824.7
C6orf89
chromosome 6 open reading frame 89
chr7_+_129225007 0.20 ENST00000325006.7
ENST00000446544.6
AHCYL2
adenosylhomocysteinase like 2
chr5_+_111224374 0.20 ENST00000282356.9
CAMK4
calcium/calmodulin dependent protein kinase IV
chr21_-_32771712 0.19 ENST00000331923.9
PAXBP1
PAX3 and PAX7 binding protein 1
chr6_-_56247525 0.19 ENST00000244728.10
COL21A1
collagen type XXI alpha 1 chain
chr8_-_65842051 0.18 ENST00000401827.8
PDE7A
phosphodiesterase 7A
chr6_+_70413462 0.18 ENST00000418814.7
ENST00000515280.5
ENST00000507085.5
ENST00000457062.6
ENST00000361499.7
FAM135A
family with sequence similarity 135 member A
chr11_-_18634332 0.17 ENST00000336349.6
SPTY2D1
SPT2 chromatin protein domain containing 1
chr8_+_66667572 0.17 ENST00000520044.5
ENST00000519289.1
ENST00000521113.1
ENST00000661636.1
ENST00000521889.5
C8orf44-SGK3
C8orf44
C8orf44-SGK3 readthrough
chromosome 8 open reading frame 44
chr1_+_2228310 0.17 ENST00000378536.5
SKI
SKI proto-oncogene
chr4_+_122826679 0.16 ENST00000264498.8
FGF2
fibroblast growth factor 2
chr19_+_11374658 0.16 ENST00000674460.1
ENST00000312423.4
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr2_-_173965356 0.15 ENST00000310015.12
SP3
Sp3 transcription factor
chr12_+_93377883 0.14 ENST00000337179.9
ENST00000415493.7
NUDT4
nudix hydrolase 4
chr1_+_35807974 0.14 ENST00000373210.4
AGO4
argonaute RISC component 4
chr3_-_18425295 0.14 ENST00000338745.11
ENST00000450898.1
SATB1
SATB homeobox 1
chr9_-_19102887 0.13 ENST00000380502.8
HAUS6
HAUS augmin like complex subunit 6
chr2_+_46698909 0.13 ENST00000650611.1
ENST00000306503.5
LINC01118
SOCS5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr1_+_35931076 0.13 ENST00000397828.3
ENST00000373191.9
AGO3
argonaute RISC catalytic component 3
chr14_+_94026314 0.13 ENST00000203664.10
ENST00000553723.1
OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr5_+_151771884 0.11 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP1
G3BP stress granule assembly factor 1
chr3_+_179148341 0.11 ENST00000263967.4
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr1_+_193121950 0.10 ENST00000367435.5
CDC73
cell division cycle 73
chr13_-_28495079 0.10 ENST00000615840.4
ENST00000282397.9
ENST00000541932.5
ENST00000539099.1
ENST00000639477.1
FLT1
fms related receptor tyrosine kinase 1
chr15_+_49423233 0.10 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
FGF7
fibroblast growth factor 7
chr7_+_66628864 0.09 ENST00000639828.2
ENST00000275532.8
ENST00000640385.1
KCTD7
potassium channel tetramerization domain containing 7
chr4_-_39977836 0.09 ENST00000303538.13
ENST00000503396.5
PDS5A
PDS5 cohesin associated factor A
chr2_+_177212724 0.08 ENST00000677043.1
ENST00000677863.1
ENST00000676681.1
ENST00000678111.1
ENST00000676874.1
ENST00000676736.1
ENST00000411529.6
ENST00000435711.5
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
chr2_+_147845020 0.08 ENST00000241416.12
ACVR2A
activin A receptor type 2A
chr19_+_34172492 0.07 ENST00000544216.8
ENST00000540746.6
ENST00000433627.9
LSM14A
LSM14A mRNA processing body assembly factor
chr17_+_59893046 0.07 ENST00000393021.7
ENST00000225577.9
ENST00000443572.6
ENST00000406116.7
RPS6KB1
ribosomal protein S6 kinase B1
chr12_-_24949026 0.07 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
BCAT1
branched chain amino acid transaminase 1
chr22_-_49824804 0.07 ENST00000216267.12
ENST00000457780.3
BRD1
bromodomain containing 1
chr8_+_60678705 0.06 ENST00000423902.7
CHD7
chromodomain helicase DNA binding protein 7
chr2_+_207529892 0.06 ENST00000432329.6
ENST00000445803.5
CREB1
cAMP responsive element binding protein 1
chr9_+_114587706 0.05 ENST00000677115.1
ENST00000677452.1
ENST00000374050.4
ENST00000677498.1
ENST00000679150.1
ATP6V1G1
ATPase H+ transporting V1 subunit G1
chr3_+_49689531 0.05 ENST00000432042.5
ENST00000454491.5
ENST00000327697.11
RNF123
ring finger protein 123
chr16_+_67029133 0.04 ENST00000290858.11
ENST00000412916.7
ENST00000564034.6
CBFB
core-binding factor subunit beta
chr2_+_119759875 0.03 ENST00000263708.7
PTPN4
protein tyrosine phosphatase non-receptor type 4
chr1_+_88684222 0.03 ENST00000316005.11
ENST00000370521.8
PKN2
protein kinase N2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.8 3.1 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 1.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.5 2.0 GO:0009956 radial pattern formation(GO:0009956)
0.5 2.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 2.7 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.4 1.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.4 1.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4 5.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.4 3.6 GO:0070836 caveola assembly(GO:0070836)
0.3 0.7 GO:1900175 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.3 1.7 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.3 1.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 0.9 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 2.9 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.3 0.9 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.3 0.8 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3 0.8 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 0.7 GO:0071284 establishment of blood-nerve barrier(GO:0008065) cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 1.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 1.0 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.2 1.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.7 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 2.0 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.2 1.2 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.2 3.3 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 1.3 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.4 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 1.5 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 2.8 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.4 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 1.6 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 1.2 GO:1901725 regulation of histone deacetylase activity(GO:1901725) positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.2 GO:2000836 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.1 3.3 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.6 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.5 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 1.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 1.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.5 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.8 GO:0030578 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.5 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.1 3.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.9 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.6 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 2.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.5 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.3 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.4 GO:0043586 tongue development(GO:0043586)
0.1 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.5 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 1.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 1.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0071543 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 1.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:2000546 chondroblast differentiation(GO:0060591) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.3 GO:0060242 contact inhibition(GO:0060242)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 1.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.3 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.1 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 1.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 1.7 GO:0035976 AP1 complex(GO:0035976)
0.2 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 0.7 GO:0070695 FHF complex(GO:0070695)
0.2 0.5 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.1 0.4 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 2.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.7 GO:0016600 flotillin complex(GO:0016600)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.3 GO:0030914 STAGA complex(GO:0030914)
0.1 0.4 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 6.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 7.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 3.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.0 3.6 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 7.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.8 GO:0001772 immunological synapse(GO:0001772)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 1.2 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.8 GO:0035577 azurophil granule membrane(GO:0035577)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.6 2.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 1.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 1.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 3.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 0.9 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.2 1.9 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 0.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 5.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.8 GO:0032810 sterol response element binding(GO:0032810)
0.2 1.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 1.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.2 2.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 1.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 1.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 1.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 2.1 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 3.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 4.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.9 GO:0001671 RNA polymerase II transcription corepressor activity(GO:0001106) ATPase activator activity(GO:0001671)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 5.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 3.8 GO:0005178 integrin binding(GO:0005178)
0.0 11.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.7 GO:0004519 endonuclease activity(GO:0004519)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.5 PID MYC PATHWAY C-MYC pathway
0.0 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.9 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 7.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 5.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events