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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UAUUGCU

Z-value: 4.15

Motif logo

miRNA associated with seed UAUUGCU

NamemiRBASE accession
MIMAT0000429

Activity profile of UAUUGCU motif

Sorted Z-values of UAUUGCU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UAUUGCU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_131796921 16.52 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr2_+_112275588 15.53 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr11_-_113875555 14.76 ENST00000003302.8
ENST00000545540.5
ubiquitin specific peptidase 28
chr6_+_11537738 11.33 ENST00000379426.2
transmembrane protein 170B
chr18_-_61892997 9.41 ENST00000312828.4
ring finger protein 152
chr4_+_7043315 8.81 ENST00000310074.8
ENST00000512388.1
transcriptional adaptor 2B
chr7_+_139231225 8.74 ENST00000473989.8
ubinuclein 2
chr22_+_41381923 8.68 ENST00000266304.9
TEF transcription factor, PAR bZIP family member
chr17_-_76240478 8.28 ENST00000269391.11
ring finger protein 157
chr19_+_1205761 8.12 ENST00000326873.12
ENST00000586243.5
serine/threonine kinase 11
chr8_+_141391989 8.10 ENST00000520105.5
ENST00000523147.5
ENST00000521578.6
protein tyrosine phosphatase 4A3
chr5_-_172771187 7.83 ENST00000239223.4
dual specificity phosphatase 1
chr7_-_35695120 7.69 ENST00000311350.8
ENST00000396081.5
HERPUD family member 2
chr20_+_56358938 7.69 ENST00000371384.4
ENST00000437418.1
family with sequence similarity 210 member B
chr1_+_236686454 7.67 ENST00000542672.6
ENST00000366578.6
ENST00000682015.1
ENST00000651275.1
actinin alpha 2
chr11_-_18634332 7.29 ENST00000336349.6
SPT2 chromatin protein domain containing 1
chr8_-_65842051 7.21 ENST00000401827.8
phosphodiesterase 7A
chr8_+_38176802 7.03 ENST00000287322.5
BAG cochaperone 4
chr12_-_42144823 6.97 ENST00000398675.8
glucoside xylosyltransferase 1
chr1_+_43650118 6.90 ENST00000372396.4
lysine demethylase 4A
chr4_+_127965394 6.81 ENST00000645843.2
ENST00000388795.9
abhydrolase domain containing 18
chr14_-_44961889 6.79 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
kelch like family member 28
chr19_-_11481044 6.78 ENST00000359227.8
ELAV like RNA binding protein 3
chrX_+_129779930 6.77 ENST00000356892.4
SAM and SH3 domain containing 3
chr7_-_44885446 6.76 ENST00000395699.5
purine rich element binding protein B
chr18_+_46334007 6.53 ENST00000269439.12
ENST00000590330.1
ring finger protein 165
chr18_-_76495191 6.46 ENST00000443185.7
zinc finger protein 516
chr2_-_9003657 6.42 ENST00000462696.1
ENST00000305997.8
membrane bound O-acyltransferase domain containing 2
chr15_-_58065703 6.20 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr2_-_201071579 6.19 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
family with sequence similarity 126 member B
chr6_+_57090069 6.18 ENST00000370708.8
ENST00000370702.5
zinc finger protein 451
chr2_+_10043524 6.18 ENST00000305883.6
Kruppel like factor 11
chr17_-_1628808 6.16 ENST00000301335.10
solute carrier family 43 member 2
chr19_+_4007714 6.12 ENST00000262971.3
protein inhibitor of activated STAT 4
chr12_+_119668109 6.05 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr17_-_65056659 5.99 ENST00000439174.7
G protein subunit alpha 13
chrX_+_111096136 5.85 ENST00000372007.10
p21 (RAC1) activated kinase 3
chr2_-_25252251 5.83 ENST00000380746.8
ENST00000402667.1
DNA methyltransferase 3 alpha
chr9_-_107489754 5.83 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr22_+_29480211 5.72 ENST00000310624.7
neurofilament heavy
chr1_-_155562693 5.69 ENST00000368346.7
ENST00000392403.8
ENST00000679333.1
ENST00000679133.1
ASH1 like histone lysine methyltransferase
chr5_-_65722094 5.66 ENST00000381007.9
small glutamine rich tetratricopeptide repeat containing beta
chr20_+_24469623 5.65 ENST00000376862.4
synapse differentiation inducing 1
chrX_-_40735476 5.63 ENST00000324817.6
mediator complex subunit 14
chr2_+_69915100 5.59 ENST00000264444.7
MAX dimerization protein 1
chr6_+_106098933 5.49 ENST00000369089.3
PR/SET domain 1
chr12_+_69470349 5.48 ENST00000547219.5
ENST00000550316.5
ENST00000548154.5
ENST00000547414.5
ENST00000549921.6
ENST00000550389.5
ENST00000550937.5
ENST00000549092.5
ENST00000550169.5
fibroblast growth factor receptor substrate 2
chr14_+_92923143 5.44 ENST00000216492.10
ENST00000334654.4
chromogranin A
chr4_-_152536045 5.40 ENST00000603548.6
ENST00000281708.10
F-box and WD repeat domain containing 7
chr18_+_9136757 5.39 ENST00000262126.9
ENST00000577992.1
ankyrin repeat domain 12
chr11_+_121452291 5.38 ENST00000260197.12
sortilin related receptor 1
chr12_+_54008961 5.34 ENST00000040584.6
homeobox C8
chr19_-_45160815 5.31 ENST00000317951.6
NTPase KAP family P-loop domain containing 1
chr20_+_46029206 5.31 ENST00000243964.7
solute carrier family 12 member 5
chr15_-_34336749 5.24 ENST00000397707.6
ENST00000560611.5
solute carrier family 12 member 6
chr7_-_122886706 5.22 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr4_+_54657918 5.06 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr9_-_120714457 5.04 ENST00000373930.4
multiple EGF like domains 9
chr11_-_66568524 5.03 ENST00000679160.1
ENST00000678305.1
ENST00000310325.10
ENST00000677896.1
ENST00000677587.1
ENST00000679347.1
ENST00000677005.1
ENST00000678872.1
ENST00000679024.1
ENST00000678471.1
ENST00000524994.6
cathepsin F
chr17_-_39607876 4.98 ENST00000302584.5
neuronal differentiation 2
chr7_-_140176970 4.90 ENST00000397560.7
lysine demethylase 7A
chr7_-_44490609 4.86 ENST00000355451.8
NudC domain containing 3
chr12_-_120369156 4.85 ENST00000257552.7
musashi RNA binding protein 1
chr1_-_38005484 4.82 ENST00000373016.4
four and a half LIM domains 3
chr3_-_21751189 4.77 ENST00000281523.8
zinc finger protein 385D
chr20_+_38805686 4.77 ENST00000299824.6
ENST00000373331.2
protein phosphatase 1 regulatory subunit 16B
chr7_+_107044689 4.76 ENST00000265717.5
protein kinase cAMP-dependent type II regulatory subunit beta
chr12_+_104064520 4.69 ENST00000229330.9
host cell factor C2
chrX_+_21839599 4.56 ENST00000379484.10
membrane bound transcription factor peptidase, site 2
chr20_-_44311142 4.55 ENST00000396825.4
fat storage inducing transmembrane protein 2
chr2_-_181680490 4.53 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
ceramide kinase like
neuronal differentiation 1
chr17_-_44503369 4.50 ENST00000585614.1
ENST00000591680.6
G-patch domain containing 8
chr3_+_49554436 4.48 ENST00000296452.5
bassoon presynaptic cytomatrix protein
chr1_+_89995102 4.46 ENST00000340281.9
ENST00000361911.9
ENST00000370447.3
zinc finger protein 326
chr11_-_73598183 4.44 ENST00000064778.8
family with sequence similarity 168 member A
chr19_+_48619489 4.40 ENST00000245222.9
sphingosine kinase 2
chr11_-_64803152 4.38 ENST00000439069.5
ENST00000294066.7
ENST00000377350.7
mitogen-activated protein kinase kinase kinase kinase 2
chr21_-_17819386 4.34 ENST00000400559.7
ENST00000400558.7
chromosome 21 open reading frame 91
chr4_+_48016764 4.32 ENST00000295461.10
NIPA like domain containing 1
chr11_+_128694052 4.30 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_90296824 4.30 ENST00000257749.9
BTB domain and CNC homolog 2
chr12_+_4909895 4.26 ENST00000638821.1
ENST00000382545.5
novel transcript, sense overlapping KCNA1
potassium voltage-gated channel subfamily A member 1
chr7_+_155458129 4.23 ENST00000297375.4
engrailed homeobox 2
chr12_+_55019967 4.20 ENST00000242994.4
neuronal differentiation 4
chr1_-_40665654 4.19 ENST00000372684.8
regulating synaptic membrane exocytosis 3
chr10_-_35642286 4.17 ENST00000374694.3
frizzled class receptor 8
chr19_+_35269065 4.16 ENST00000595068.5
ENST00000379134.7
ENST00000594064.5
ENST00000598058.1
upstream transcription factor 2, c-fos interacting
chr3_+_10992717 4.12 ENST00000642767.1
ENST00000425938.6
ENST00000642515.1
ENST00000643498.1
ENST00000646072.1
ENST00000646570.1
ENST00000287766.10
ENST00000645281.1
ENST00000642820.1
ENST00000645054.1
ENST00000642735.1
ENST00000646022.1
ENST00000645776.1
ENST00000645592.1
ENST00000646924.1
ENST00000645974.1
ENST00000644314.1
ENST00000642639.1
ENST00000646060.1
ENST00000642201.1
ENST00000646487.1
ENST00000647194.1
ENST00000646088.1
solute carrier family 6 member 1
chr11_-_119729158 4.10 ENST00000264025.8
nectin cell adhesion molecule 1
chr5_+_153490655 4.09 ENST00000518142.5
ENST00000285900.10
glutamate ionotropic receptor AMPA type subunit 1
chr5_+_56815534 4.06 ENST00000399503.4
mitogen-activated protein kinase kinase kinase 1
chr1_-_72282457 4.04 ENST00000357731.10
neuronal growth regulator 1
chr14_-_99272184 4.04 ENST00000357195.8
BAF chromatin remodeling complex subunit BCL11B
chr1_+_95117324 3.98 ENST00000370203.9
ENST00000456991.5
TLC domain containing 4
chr11_-_62591554 3.98 ENST00000494385.1
ENST00000308436.11
terminal uridylyl transferase 1, U6 snRNA-specific
chr18_-_55588184 3.96 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr5_-_94111627 3.96 ENST00000505869.5
ENST00000395965.8
ENST00000509163.5
family with sequence similarity 172 member A
chr4_-_89307732 3.95 ENST00000609438.2
GPRIN family member 3
chr5_+_80035341 3.94 ENST00000350881.6
thrombospondin 4
chr21_+_43865200 3.92 ENST00000291572.13
1-acylglycerol-3-phosphate O-acyltransferase 3
chr19_+_1285859 3.86 ENST00000215368.4
ephrin A2
chr4_-_140427635 3.84 ENST00000325617.10
ENST00000414773.5
calmegin
chr12_+_122835426 3.84 ENST00000253083.9
huntingtin interacting protein 1 related
chr9_+_112486819 3.82 ENST00000337530.11
KIAA1958
chr16_-_2214776 3.82 ENST00000333503.8
phosphoglycolate phosphatase
chr12_-_52680398 3.80 ENST00000252244.3
keratin 1
chr17_+_55264952 3.79 ENST00000226067.10
HLF transcription factor, PAR bZIP family member
chr13_+_23180960 3.78 ENST00000218867.4
sarcoglycan gamma
chr4_+_88592426 3.75 ENST00000431413.5
ENST00000402738.6
ENST00000422770.5
ENST00000407637.5
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr1_+_155002630 3.75 ENST00000535420.5
ENST00000417934.6
ENST00000368426.3
zinc finger and BTB domain containing 7B
chr6_-_30075767 3.74 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr9_-_89178810 3.70 ENST00000375835.9
SHC adaptor protein 3
chr3_-_115071333 3.69 ENST00000462705.5
zinc finger and BTB domain containing 20
chrX_-_154805386 3.69 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
membrane palmitoylated protein 1
chr19_+_49527988 3.68 ENST00000270645.8
reticulocalbin 3
chr14_-_99604167 3.63 ENST00000380243.9
coiled-coil domain containing 85C
chr6_-_46325641 3.62 ENST00000330430.10
ENST00000405162.2
regulator of calcineurin 2
chr16_+_68023276 3.56 ENST00000567100.5
ENST00000565263.6
ENST00000432752.5
ENST00000569289.5
ENST00000564781.1
dihydrouridine synthase 2
chr7_+_21428023 3.54 ENST00000432066.2
ENST00000222584.8
Sp4 transcription factor
chr2_-_216695540 3.52 ENST00000233813.5
insulin like growth factor binding protein 5
chr4_+_77157189 3.51 ENST00000316355.10
ENST00000502280.5
cyclin G2
chr18_+_13218769 3.50 ENST00000677055.1
ENST00000399848.7
low density lipoprotein receptor class A domain containing 4
chr15_+_64841873 3.49 ENST00000616065.4
ENST00000323544.5
pleckstrin homology domain containing O2
chr15_+_79432330 3.49 ENST00000305428.8
membrane integral NOTCH2 associated receptor 1
chr3_-_126357399 3.49 ENST00000296233.4
Kruppel like factor 15
chr11_+_65711991 3.48 ENST00000377046.7
ENST00000352980.8
lysine acetyltransferase 5
chr18_+_70288991 3.46 ENST00000397942.4
suppressor of cytokine signaling 6
chr14_+_64704380 3.46 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chr2_-_43226594 3.44 ENST00000282388.4
ZFP36 ring finger protein like 2
chrX_+_129982610 3.40 ENST00000218147.11
ENST00000540052.6
BCL6 corepressor like 1
chr1_+_169368175 3.38 ENST00000367808.8
ENST00000426663.1
basic leucine zipper nuclear factor 1
chr20_+_33490073 3.38 ENST00000342704.11
ENST00000375279.6
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr16_+_66844914 3.37 ENST00000394069.3
carbonic anhydrase 7
chr1_-_31239880 3.37 ENST00000373736.7
sodium/potassium transporting ATPase interacting 1
chr7_+_139341311 3.32 ENST00000297534.7
ENST00000541515.3
formation of mitochondrial complex V assembly factor 1 homolog
FMC1-LUC7L2 readthrough
chr10_-_51699559 3.32 ENST00000331173.6
cleavage stimulation factor subunit 2 tau variant
chr10_+_114043858 3.31 ENST00000369295.4
adrenoceptor beta 1
chr1_+_212950572 3.29 ENST00000366968.8
ENST00000490792.1
ENST00000366964.7
vasohibin 2
chr12_+_78864768 3.23 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr22_+_41560973 3.23 ENST00000306149.12
cold shock domain containing C2
chr2_+_86720282 3.22 ENST00000283632.5
required for meiotic nuclear division 5 homolog A
chr19_+_10420474 3.22 ENST00000380702.7
phosphodiesterase 4A
chrX_+_118974608 3.21 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr11_-_1572261 3.19 ENST00000397374.8
dual specificity phosphatase 8
chr9_-_98708856 3.17 ENST00000259455.4
gamma-aminobutyric acid type B receptor subunit 2
chr11_+_118436464 3.17 ENST00000389506.10
ENST00000534358.8
ENST00000531904.6
ENST00000649699.1
lysine methyltransferase 2A
chr15_-_79090760 3.15 ENST00000419573.7
ENST00000558480.7
Ras protein specific guanine nucleotide releasing factor 1
chr10_-_72088533 3.15 ENST00000373109.7
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr1_-_46132616 3.14 ENST00000423209.5
ENST00000262741.10
phosphoinositide-3-kinase regulatory subunit 3
chr4_+_92303946 3.13 ENST00000282020.9
glutamate ionotropic receptor delta type subunit 2
chr2_+_176107272 3.12 ENST00000249504.7
homeobox D11
chr19_+_589873 3.10 ENST00000251287.3
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
chr12_+_56007484 3.09 ENST00000262032.9
IKAROS family zinc finger 4
chr12_+_2052977 3.08 ENST00000399634.6
ENST00000406454.8
ENST00000327702.12
ENST00000347598.9
ENST00000399603.6
ENST00000399641.6
ENST00000399655.6
ENST00000335762.10
ENST00000682835.1
calcium voltage-gated channel subunit alpha1 C
chr16_+_11668414 3.08 ENST00000329565.6
stannin
chr12_+_69239560 3.07 ENST00000435070.7
cleavage and polyadenylation specific factor 6
chr7_+_98106852 3.03 ENST00000297293.6
lemur tyrosine kinase 2
chr12_-_53727428 3.02 ENST00000548263.5
ENST00000430117.6
ENST00000549173.5
ENST00000550804.6
ENST00000551900.5
ENST00000546619.5
ENST00000548177.5
ENST00000549349.5
calcium binding and coiled-coil domain 1
chr12_+_53380639 3.00 ENST00000426431.2
Sp1 transcription factor
chr7_+_4682252 2.99 ENST00000328914.5
forkhead box K1
chr11_+_24497155 2.97 ENST00000529015.5
ENST00000533227.5
leucine zipper protein 2
chr14_+_73644875 2.97 ENST00000554113.5
ENST00000553645.7
ENST00000555631.6
ENST00000311089.7
ENST00000555919.7
ENST00000554339.5
ENST00000554871.5
dynein axonemal light chain 1
chr1_+_213987929 2.97 ENST00000498508.6
ENST00000366958.9
prospero homeobox 1
chr3_+_37452121 2.95 ENST00000264741.10
integrin subunit alpha 9
chr19_+_16324817 2.94 ENST00000248071.6
ENST00000592003.1
Kruppel like factor 2
chr17_+_50561010 2.89 ENST00000360761.8
ENST00000354983.8
ENST00000352832.9
calcium voltage-gated channel subunit alpha1 G
chr7_-_72336995 2.88 ENST00000329008.9
calneuron 1
chr10_+_94402486 2.87 ENST00000225235.5
TBC1 domain family member 12
chr21_+_29298890 2.86 ENST00000286800.8
BTB domain and CNC homolog 1
chr1_+_222618075 2.86 ENST00000344922.10
MIA SH3 domain ER export factor 3
chr6_+_63635792 2.85 ENST00000262043.8
ENST00000506783.5
ENST00000481385.6
ENST00000515594.5
ENST00000494284.6
PHD finger protein 3
chr14_-_81220951 2.82 ENST00000553612.6
general transcription factor IIA subunit 1
chrX_+_154458274 2.82 ENST00000369682.4
plexin A3
chr15_-_45522747 2.81 ENST00000261867.5
solute carrier family 30 member 4
chrX_-_46759055 2.78 ENST00000328306.4
ENST00000616978.5
solute carrier family 9 member A7
chr12_-_49110840 2.77 ENST00000550137.5
ENST00000267102.13
ENST00000547382.5
limb development membrane protein 1 like
chr11_-_132943671 2.77 ENST00000331898.11
opioid binding protein/cell adhesion molecule like
chr11_-_107018462 2.77 ENST00000526355.7
guanylate cyclase 1 soluble subunit alpha 2
chr1_+_220528112 2.76 ENST00000366917.6
ENST00000402574.5
ENST00000611084.4
ENST00000366918.8
microtubule affinity regulating kinase 1
chr17_-_64263221 2.75 ENST00000258991.7
ENST00000583738.1
ENST00000584379.6
testis expressed 2
chr1_+_15617415 2.74 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr3_-_69052309 2.73 ENST00000398559.7
ENST00000646708.1
ENST00000646304.1
TATA element modulatory factor 1
chr14_-_24442765 2.72 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
short chain dehydrogenase/reductase family 39U member 1
chr5_+_7396099 2.71 ENST00000338316.9
adenylate cyclase 2
chr2_+_156436423 2.70 ENST00000540309.5
glycerol-3-phosphate dehydrogenase 2
chr19_+_35030438 2.68 ENST00000415950.5
ENST00000262631.11
sodium voltage-gated channel beta subunit 1
chr5_-_40798160 2.67 ENST00000296800.4
ENST00000397128.6
protein kinase AMP-activated catalytic subunit alpha 1
chr9_-_109167159 2.65 ENST00000561981.5
ferric chelate reductase 1 like
chr17_-_7929793 2.65 ENST00000303790.3
potassium voltage-gated channel subfamily A regulatory beta subunit 3
chr11_-_790062 2.64 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr2_+_165239388 2.61 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
sodium voltage-gated channel alpha subunit 2
chr9_-_10612966 2.59 ENST00000381196.9
protein tyrosine phosphatase receptor type D
chr21_-_32727933 2.57 ENST00000357345.7
ENST00000429236.5
synaptojanin 1
chr5_+_31639104 2.53 ENST00000438447.2
PDZ domain containing 2
chr8_-_143541425 2.53 ENST00000262577.6
zinc finger CCCH-type containing 3
chr11_-_45665578 2.53 ENST00000308064.7
carbohydrate sulfotransferase 1
chr11_+_17734732 2.51 ENST00000379472.4
ENST00000675775.1
ENST00000265969.8
ENST00000640318.2
ENST00000639325.2
potassium voltage-gated channel subfamily C member 1
chr2_+_66435558 2.50 ENST00000488550.5
Meis homeobox 1
chr5_-_176899332 2.50 ENST00000292432.10
hexokinase 3
chr20_+_43457885 2.50 ENST00000668808.1
ENST00000670741.1
ENST00000662078.1
ENST00000244020.5
ENST00000657241.1
serine and arginine rich splicing factor 6
novel protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
2.8 8.5 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
2.7 10.8 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.4 7.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
2.1 6.2 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
1.9 7.7 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
1.8 5.5 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
1.8 5.4 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
1.8 5.4 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.7 5.1 GO:0070662 erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662)
1.6 4.9 GO:0035574 histone H4-K20 demethylation(GO:0035574)
1.6 17.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.6 4.8 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.5 9.0 GO:0035881 amacrine cell differentiation(GO:0035881)
1.5 4.5 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.5 4.4 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
1.4 5.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
1.4 5.7 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
1.4 4.1 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
1.3 5.4 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.3 4.0 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
1.3 3.9 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
1.2 3.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
1.2 5.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.2 3.7 GO:0061386 closure of optic fissure(GO:0061386)
1.2 3.5 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.1 3.3 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
1.1 4.4 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
1.1 3.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.1 3.2 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) positive regulation of response to drug(GO:2001025)
1.0 4.2 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
1.0 3.0 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.0 5.8 GO:0090116 C-5 methylation of cytosine(GO:0090116)
1.0 3.8 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.9 2.7 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.9 5.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.9 6.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.9 6.9 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.8 2.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.8 1.7 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.8 4.8 GO:0097338 response to clozapine(GO:0097338)
0.8 7.0 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.8 2.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.8 2.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.8 2.3 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.8 6.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.7 5.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.7 5.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.7 2.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.7 6.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.7 2.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.7 2.7 GO:2000843 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.7 4.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.7 3.4 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.7 2.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.7 6.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.7 7.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.7 6.6 GO:1990504 dense core granule exocytosis(GO:1990504)
0.6 4.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.6 2.6 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.6 3.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.6 9.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.6 3.9 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.5 2.7 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.5 1.6 GO:1990009 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.5 2.6 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.5 3.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.5 7.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.5 1.9 GO:1905069 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) allantois development(GO:1905069)
0.5 4.3 GO:0015693 magnesium ion transport(GO:0015693)
0.5 0.9 GO:0090427 activation of meiosis(GO:0090427)
0.5 5.2 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.5 1.9 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.5 0.9 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.5 1.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.5 1.9 GO:0048865 stem cell fate commitment(GO:0048865)
0.5 4.1 GO:0070166 enamel mineralization(GO:0070166)
0.5 4.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 2.2 GO:0016240 autophagosome docking(GO:0016240)
0.4 2.7 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.4 7.1 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.4 3.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.4 2.2 GO:0021764 amygdala development(GO:0021764)
0.4 6.1 GO:0035878 nail development(GO:0035878)
0.4 1.3 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 2.4 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.4 1.5 GO:0099558 maintenance of synapse structure(GO:0099558)
0.4 4.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 6.8 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.4 2.8 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.4 2.8 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.3 2.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 1.0 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.3 2.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.3 4.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.3 1.9 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.3 1.3 GO:0060013 righting reflex(GO:0060013)
0.3 1.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.3 12.3 GO:1901985 positive regulation of protein acetylation(GO:1901985)
0.3 1.2 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.3 5.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.3 0.9 GO:1902732 growth involved in heart morphogenesis(GO:0003241) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) regulation of chromatin silencing at telomere(GO:0031938) positive regulation of chondrocyte proliferation(GO:1902732)
0.3 0.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.3 6.2 GO:0035855 megakaryocyte development(GO:0035855)
0.3 3.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3 2.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.3 2.8 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 3.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 2.8 GO:0090335 regulation of brown fat cell differentiation(GO:0090335)
0.3 4.2 GO:1990403 embryonic brain development(GO:1990403)
0.3 6.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.3 1.5 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.3 6.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.3 3.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 6.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.2 1.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 2.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 2.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 1.6 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 2.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 1.4 GO:0035063 nuclear speck organization(GO:0035063)
0.2 11.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 9.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 1.3 GO:0060017 parathyroid gland development(GO:0060017)
0.2 1.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.2 2.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 3.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 2.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 2.7 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 1.7 GO:0042426 choline catabolic process(GO:0042426)
0.2 2.4 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.2 0.8 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 3.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 1.2 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.2 3.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 2.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 1.9 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 1.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2 2.1 GO:0097107 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 0.9 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.2 3.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 2.0 GO:0001842 neural fold formation(GO:0001842)
0.2 2.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 2.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 1.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.2 1.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 2.4 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.2 1.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 0.9 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.2 4.5 GO:0007616 long-term memory(GO:0007616)
0.2 0.8 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 2.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.2 1.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 7.1 GO:0019228 neuronal action potential(GO:0019228)
0.1 3.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 6.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 1.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 2.8 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 0.7 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 2.5 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 1.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 6.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 2.0 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 11.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 1.5 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 1.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 5.7 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.3 GO:1902722 positive regulation of prolactin secretion(GO:1902722)
0.1 2.5 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.4 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 3.8 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.1 3.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 3.5 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 3.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 1.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0044351 macropinocytosis(GO:0044351)
0.1 1.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.9 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1 0.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 2.5 GO:0006853 carnitine shuttle(GO:0006853)
0.1 6.0 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 2.1 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 2.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.1 5.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.6 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 1.5 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.1 1.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 3.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 2.7 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 3.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 6.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 3.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 3.7 GO:0046710 GDP metabolic process(GO:0046710)
0.1 2.2 GO:0021772 olfactory bulb development(GO:0021772)
0.1 4.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 3.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.4 GO:0045837 negative regulation of membrane potential(GO:0045837)
0.1 3.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 2.6 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 1.5 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 1.5 GO:0030220 platelet formation(GO:0030220)
0.1 4.2 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.1 1.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 2.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 3.1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.6 GO:0060174 limb bud formation(GO:0060174)
0.1 0.9 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 3.6 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.1 GO:1904339 negative regulation of NFAT protein import into nucleus(GO:0051534) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 1.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.3 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 2.5 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.1 GO:0021546 rhombomere development(GO:0021546) rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 3.1 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.1 0.1 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.1 1.0 GO:0090129 regulation of synapse maturation(GO:0090128) positive regulation of synapse maturation(GO:0090129)
0.1 1.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 2.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.8 GO:0035690 cellular response to drug(GO:0035690)
0.1 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 2.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 3.4 GO:0098727 maintenance of cell number(GO:0098727)
0.0 2.4 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 5.6 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 1.9 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 1.3 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.6 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 1.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 2.3 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.7 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 2.1 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760)
0.0 1.2 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 2.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 2.1 GO:0032526 response to retinoic acid(GO:0032526)
0.0 5.0 GO:0006813 potassium ion transport(GO:0006813)
0.0 4.6 GO:0045637 regulation of myeloid cell differentiation(GO:0045637)
0.0 2.9 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.0 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.8 GO:0045576 mast cell activation(GO:0045576)
0.0 2.3 GO:0065004 protein-DNA complex assembly(GO:0065004)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 8.9 GO:0036398 TCR signalosome(GO:0036398)
1.5 4.5 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
1.5 4.5 GO:0044609 DBIRD complex(GO:0044609)
1.2 4.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.1 5.6 GO:0070847 core mediator complex(GO:0070847)
1.1 3.2 GO:0034657 GID complex(GO:0034657)
0.9 0.9 GO:0031933 telomeric heterochromatin(GO:0031933)
0.9 3.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.8 4.1 GO:0044308 axonal spine(GO:0044308)
0.8 3.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.8 5.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.7 4.1 GO:0032584 growth cone membrane(GO:0032584)
0.6 3.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.6 1.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.6 10.2 GO:0030914 STAGA complex(GO:0030914)
0.6 11.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.5 2.2 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.5 2.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5 3.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 2.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 3.0 GO:0036157 outer dynein arm(GO:0036157)
0.4 6.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 1.6 GO:0070876 SOSS complex(GO:0070876)
0.4 8.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 5.8 GO:0001741 XY body(GO:0001741)
0.4 5.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.4 3.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.3 6.9 GO:0033270 paranode region of axon(GO:0033270)
0.3 2.0 GO:0032279 asymmetric synapse(GO:0032279)
0.3 5.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 7.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.3 4.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 2.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 2.5 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.3 2.1 GO:0036020 endolysosome membrane(GO:0036020)
0.3 0.9 GO:0000125 PCAF complex(GO:0000125)
0.3 5.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 2.2 GO:0042583 chromaffin granule(GO:0042583)
0.3 5.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 6.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 0.7 GO:0032116 SMC loading complex(GO:0032116)
0.2 14.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 5.4 GO:0048786 presynaptic active zone(GO:0048786)
0.2 7.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 4.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 6.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 11.7 GO:0043198 dendritic shaft(GO:0043198)
0.2 1.5 GO:0061689 tricellular tight junction(GO:0061689)
0.2 1.7 GO:0033391 chromatoid body(GO:0033391)
0.2 0.7 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 2.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0005879 axonemal microtubule(GO:0005879)
0.1 5.1 GO:0042629 mast cell granule(GO:0042629)
0.1 1.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.5 GO:0071203 WASH complex(GO:0071203)
0.1 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 13.9 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.8 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 2.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 15.7 GO:0016605 PML body(GO:0016605)
0.1 3.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.6 GO:0097440 apical dendrite(GO:0097440)
0.1 3.9 GO:0016592 mediator complex(GO:0016592)
0.1 9.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.8 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 3.8 GO:0045095 keratin filament(GO:0045095)
0.1 6.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0034704 calcium channel complex(GO:0034704)
0.1 7.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 4.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.1 GO:0016235 aggresome(GO:0016235)
0.1 2.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 3.5 GO:0005844 polysome(GO:0005844)
0.1 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.6 GO:0008305 integrin complex(GO:0008305)
0.1 6.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 2.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 5.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 5.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 6.4 GO:0098793 presynapse(GO:0098793)
0.0 5.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 2.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.8 GO:0005776 autophagosome(GO:0005776)
0.0 1.4 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 2.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 5.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.6 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0000792 heterochromatin(GO:0000792)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 4.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 4.3 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 2.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 3.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
2.5 14.7 GO:0061665 SUMO ligase activity(GO:0061665)
1.6 4.9 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
1.6 8.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
1.4 4.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
1.3 3.8 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.2 5.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.2 7.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.1 3.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.1 3.2 GO:0045322 unmethylated CpG binding(GO:0045322)
1.0 4.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
1.0 2.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.0 5.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 8.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.9 2.7 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.8 3.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.8 8.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.8 2.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.8 10.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.7 7.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.7 2.9 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.7 6.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.7 5.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.7 2.7 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.7 2.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.7 7.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.7 2.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.6 3.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.6 5.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.6 4.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.6 3.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.6 1.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.6 1.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.6 7.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.6 3.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.6 7.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.6 4.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.5 7.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 2.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.5 7.8 GO:0019211 phosphatase activator activity(GO:0019211)
0.5 6.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.5 4.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.5 2.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.5 4.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 3.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 1.4 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.5 1.4 GO:0031208 POZ domain binding(GO:0031208)
0.5 4.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.4 1.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 2.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.4 4.5 GO:0046625 sphingolipid binding(GO:0046625)
0.4 1.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.4 6.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 3.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 4.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 5.5 GO:0046790 virion binding(GO:0046790)
0.4 1.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.4 10.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 4.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.4 2.3 GO:0008142 oxysterol binding(GO:0008142)
0.4 5.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.4 2.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.4 2.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.4 3.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 2.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.3 2.4 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.3 3.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 3.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 1.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 3.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 8.1 GO:0030275 LRR domain binding(GO:0030275)
0.3 5.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 3.0 GO:0050692 DBD domain binding(GO:0050692)
0.3 2.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.3 3.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 1.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 6.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 3.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 12.2 GO:0017091 AU-rich element binding(GO:0017091)
0.3 1.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.3 2.8 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3 2.5 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 11.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 4.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 3.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 24.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 0.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 3.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 4.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 4.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 0.6 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 3.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 1.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 4.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 4.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 3.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 0.7 GO:0036033 mediator complex binding(GO:0036033)
0.2 0.7 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 0.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 1.4 GO:0071253 connexin binding(GO:0071253)
0.2 7.4 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.8 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 3.1 GO:0005234 ionotropic glutamate receptor activity(GO:0004970) extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2 1.9 GO:0070700 BMP receptor binding(GO:0070700)
0.2 6.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 0.8 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 1.8 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 1.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 3.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 5.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0097677 STAT family protein binding(GO:0097677)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 8.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 4.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 3.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.8 GO:0035198 miRNA binding(GO:0035198)
0.1 2.7 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 3.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.9 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 5.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 1.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 8.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 3.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 5.9 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 0.7 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 3.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 2.9 GO:0043236 laminin binding(GO:0043236)
0.1 2.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.1 GO:0052629 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.1 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 3.5 GO:0004402 histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1 1.6 GO:0008187 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.1 3.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 4.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 4.4 GO:0002039 p53 binding(GO:0002039)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 6.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.4 GO:0005521 lamin binding(GO:0005521)
0.1 1.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0031432 titin binding(GO:0031432)
0.0 0.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 2.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.0 3.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 2.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 27.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 2.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 3.1 GO:0044325 ion channel binding(GO:0044325)
0.0 11.8 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 1.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 2.3 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0001012 RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.5 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 6.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 8.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 10.4 PID MYC PATHWAY C-MYC pathway
0.2 10.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 3.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 15.1 PID LKB1 PATHWAY LKB1 signaling events
0.2 5.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 10.9 PID TNF PATHWAY TNF receptor signaling pathway
0.2 9.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 3.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 4.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 3.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 4.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 12.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 5.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 4.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 6.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 8.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.8 PID CONE PATHWAY Visual signal transduction: Cones
0.1 5.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 9.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.7 PID AURORA A PATHWAY Aurora A signaling
0.1 2.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 3.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 3.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 7.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 7.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 4.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 19.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.4 5.5 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.4 9.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.3 5.6 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.3 10.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3 5.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 1.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.3 5.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 6.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 15.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 5.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 3.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 5.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 4.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.2 6.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.2 3.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 3.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 3.7 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.2 4.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 7.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.2 25.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 7.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 2.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.7 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 5.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 6.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 3.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 4.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 4.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 2.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 3.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 1.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 8.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 9.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 3.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.6 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 4.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.7 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 2.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.6 REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway