Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for UCACAGU
Z-value: 1.75
Motif logo
miRNA associated with seed UCACAGU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-27a-3p
|
MIMAT0000084 |
|
hsa-miR-27b-3p
|
MIMAT0000419 |
Activity profile of UCACAGU motif
Sorted Z-values of UCACAGU motif
Network of associatons between targets according to the STRING database.
First level regulatory network of UCACAGU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 11.5 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 2.1 | 6.4 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 2.0 | 6.0 | GO:0097477 | spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) |
| 1.5 | 4.5 | GO:0051939 | gamma-aminobutyric acid import(GO:0051939) |
| 1.4 | 4.1 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 1.3 | 5.1 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 1.2 | 4.9 | GO:2000638 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 1.1 | 3.3 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 1.0 | 5.1 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 1.0 | 2.9 | GO:0021722 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 1.0 | 3.9 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.9 | 3.7 | GO:0072660 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.9 | 2.6 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 0.8 | 2.3 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.7 | 2.2 | GO:0042231 | interleukin-13 biosynthetic process(GO:0042231) |
| 0.7 | 2.8 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.7 | 4.8 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.7 | 2.7 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 0.7 | 2.0 | GO:1905053 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 0.6 | 2.6 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
| 0.6 | 3.2 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.6 | 2.5 | GO:1902228 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 0.6 | 1.8 | GO:1900154 | positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
| 0.6 | 0.6 | GO:2000053 | regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) |
| 0.5 | 6.6 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.5 | 4.7 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.5 | 1.6 | GO:0060023 | soft palate development(GO:0060023) |
| 0.5 | 4.1 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.5 | 2.6 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.5 | 2.0 | GO:0036515 | serotonergic neuron axon guidance(GO:0036515) |
| 0.5 | 3.4 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 0.5 | 2.5 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 0.5 | 1.4 | GO:0072276 | metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
| 0.5 | 1.4 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.4 | 6.5 | GO:0009128 | purine nucleoside monophosphate catabolic process(GO:0009128) |
| 0.4 | 1.7 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.4 | 2.1 | GO:0072143 | mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131) |
| 0.4 | 1.2 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 0.4 | 2.0 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.4 | 1.6 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 0.4 | 1.9 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.4 | 3.4 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.4 | 1.8 | GO:0051029 | rRNA transport(GO:0051029) |
| 0.4 | 0.7 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.3 | 4.9 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.3 | 1.7 | GO:0021764 | amygdala development(GO:0021764) |
| 0.3 | 1.0 | GO:1902769 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.3 | 2.4 | GO:0072386 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.3 | 2.2 | GO:0003402 | planar cell polarity pathway involved in axis elongation(GO:0003402) |
| 0.3 | 1.6 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 0.3 | 0.9 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.3 | 0.9 | GO:0034183 | negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 0.3 | 1.5 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
| 0.3 | 2.9 | GO:0008343 | adult feeding behavior(GO:0008343) righting reflex(GO:0060013) |
| 0.3 | 5.6 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.3 | 0.9 | GO:0071676 | negative regulation of mononuclear cell migration(GO:0071676) |
| 0.3 | 1.7 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
| 0.3 | 2.0 | GO:1903433 | regulation of constitutive secretory pathway(GO:1903433) |
| 0.3 | 2.8 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.3 | 1.9 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.3 | 0.5 | GO:0014042 | positive regulation of neuron maturation(GO:0014042) |
| 0.3 | 2.4 | GO:0014052 | regulation of gamma-aminobutyric acid secretion(GO:0014052) |
| 0.3 | 1.1 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.3 | 1.5 | GO:0044254 | angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) |
| 0.2 | 0.2 | GO:1902954 | regulation of early endosome to recycling endosome transport(GO:1902954) |
| 0.2 | 1.9 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.2 | 2.3 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.2 | 1.1 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) |
| 0.2 | 3.8 | GO:0021794 | thalamus development(GO:0021794) |
| 0.2 | 1.8 | GO:0033629 | negative regulation of cell adhesion mediated by integrin(GO:0033629) |
| 0.2 | 2.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.2 | 2.5 | GO:0061000 | negative regulation of dendritic spine development(GO:0061000) |
| 0.2 | 4.0 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.2 | 2.3 | GO:0097106 | postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.2 | 2.1 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.2 | 1.2 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.2 | 3.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.2 | 1.6 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.2 | 1.8 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.2 | 2.3 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.2 | 5.6 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.2 | 1.1 | GO:0003418 | growth plate cartilage chondrocyte differentiation(GO:0003418) |
| 0.2 | 2.2 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.2 | 2.6 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 0.2 | 1.3 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.2 | 1.3 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.2 | 1.1 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.2 | 0.4 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.2 | 1.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.2 | 0.5 | GO:1902617 | response to fluoride(GO:1902617) |
| 0.2 | 2.1 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.2 | 1.5 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.2 | 0.5 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.2 | 0.7 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.2 | 1.3 | GO:0050942 | positive regulation of pigment cell differentiation(GO:0050942) |
| 0.2 | 1.4 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.2 | 0.6 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.2 | 2.4 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
| 0.2 | 1.3 | GO:0032354 | response to follicle-stimulating hormone(GO:0032354) |
| 0.2 | 0.6 | GO:1904382 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
| 0.2 | 1.4 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 2.5 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.1 | 1.2 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.1 | 2.3 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 0.1 | 1.0 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
| 0.1 | 1.7 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.1 | 0.8 | GO:0035672 | oligopeptide transmembrane transport(GO:0035672) |
| 0.1 | 3.1 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 0.4 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.1 | 4.2 | GO:0021988 | olfactory lobe development(GO:0021988) |
| 0.1 | 0.5 | GO:0097490 | sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) |
| 0.1 | 1.3 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 1.3 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 0.1 | 0.6 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 0.1 | 5.4 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.1 | 1.4 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 0.9 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.1 | 1.4 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 1.3 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 0.1 | 0.4 | GO:0003186 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) |
| 0.1 | 0.4 | GO:0019075 | virus maturation(GO:0019075) |
| 0.1 | 0.4 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.1 | 2.3 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.1 | 5.4 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.1 | 1.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 0.4 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
| 0.1 | 0.4 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.1 | 0.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 0.8 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.1 | 0.9 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 4.3 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 3.1 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.1 | 1.6 | GO:0050812 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.1 | 0.3 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.1 | 0.2 | GO:1900019 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.1 | 1.0 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 0.4 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
| 0.1 | 3.0 | GO:0050427 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.1 | 0.6 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.1 | 2.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 3.1 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.1 | 1.1 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.1 | 0.3 | GO:1904861 | excitatory synapse assembly(GO:1904861) |
| 0.1 | 1.6 | GO:1903543 | positive regulation of exosomal secretion(GO:1903543) |
| 0.1 | 1.1 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.1 | 2.1 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
| 0.1 | 1.3 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 0.1 | GO:1904782 | negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782) |
| 0.1 | 0.1 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 0.1 | 1.9 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 0.3 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.1 | 1.9 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.1 | 1.3 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.3 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
| 0.1 | 4.8 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.1 | 1.4 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.1 | 2.3 | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.1 | 0.5 | GO:1901660 | calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034) |
| 0.1 | 2.9 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 0.8 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.1 | 0.6 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
| 0.1 | 2.0 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.1 | 1.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 0.4 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.1 | 0.5 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
| 0.1 | 2.1 | GO:0009299 | mRNA transcription(GO:0009299) |
| 0.1 | 1.2 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.1 | 0.4 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.1 | 1.6 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 5.9 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 0.6 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.1 | 3.2 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.1 | 1.3 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.1 | 1.0 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.1 | 0.6 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.1 | 2.9 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.1 | 0.7 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.1 | 0.1 | GO:0044340 | canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340) |
| 0.1 | 1.6 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.1 | 0.8 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.1 | 2.1 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 1.4 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 0.9 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.1 | 0.5 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.1 | 0.2 | GO:2000542 | negative regulation of gastrulation(GO:2000542) |
| 0.1 | 6.1 | GO:0055072 | iron ion homeostasis(GO:0055072) |
| 0.1 | 0.5 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
| 0.1 | 0.3 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.1 | 0.2 | GO:0072423 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 0.1 | 1.1 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.1 | 9.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 0.4 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 2.7 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 0.3 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.1 | 1.1 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.1 | 0.5 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.1 | 2.2 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.0 | GO:0060978 | angiogenesis involved in coronary vascular morphogenesis(GO:0060978) |
| 0.0 | 0.9 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 1.2 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.0 | 0.3 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.4 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
| 0.0 | 0.7 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.0 | 0.9 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.0 | 1.9 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.0 | 2.6 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
| 0.0 | 0.1 | GO:0060671 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.0 | 0.4 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.0 | 1.0 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.7 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.0 | 0.7 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.0 | 0.2 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.0 | 8.8 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.2 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.0 | 0.3 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.0 | 2.2 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.0 | 2.1 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
| 0.0 | 0.6 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.0 | 0.5 | GO:0001964 | startle response(GO:0001964) |
| 0.0 | 0.3 | GO:0043116 | negative regulation of vascular permeability(GO:0043116) |
| 0.0 | 0.9 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.0 | 0.3 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
| 0.0 | 0.2 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 2.3 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 2.1 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.3 | GO:0060674 | placenta blood vessel development(GO:0060674) |
| 0.0 | 2.1 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.0 | 0.2 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.0 | 1.1 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.0 | 0.2 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.2 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.0 | 2.7 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 0.3 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.9 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.0 | 0.1 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.0 | 1.7 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 0.8 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.2 | GO:0042481 | regulation of odontogenesis(GO:0042481) |
| 0.0 | 0.1 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.0 | 2.2 | GO:0007626 | locomotory behavior(GO:0007626) |
| 0.0 | 0.1 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
| 0.0 | 0.4 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.0 | 1.2 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.1 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.0 | 0.9 | GO:0035773 | insulin secretion involved in cellular response to glucose stimulus(GO:0035773) |
| 0.0 | 0.4 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 0.4 | GO:0097503 | sialylation(GO:0097503) |
| 0.0 | 0.1 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 0.2 | GO:0002517 | T cell tolerance induction(GO:0002517) |
| 0.0 | 0.7 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.8 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 11.7 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 1.3 | 6.4 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 1.0 | 2.1 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 1.0 | 2.9 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.9 | 9.1 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.8 | 5.1 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.8 | 4.9 | GO:0020016 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.8 | 4.1 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.8 | 4.8 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.8 | 2.4 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.7 | 4.9 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.7 | 2.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.7 | 2.6 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
| 0.6 | 2.9 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.5 | 5.6 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.5 | 2.0 | GO:0034678 | integrin alpha8-beta1 complex(GO:0034678) |
| 0.5 | 4.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.5 | 1.8 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.4 | 3.4 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.4 | 2.5 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.4 | 2.0 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.4 | 1.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.3 | 2.2 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.3 | 0.9 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.2 | 1.7 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.2 | 5.8 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.2 | 0.8 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.2 | 1.6 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.2 | 1.8 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.2 | 3.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 1.8 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.2 | 2.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 9.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 1.5 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.2 | 1.0 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.1 | 0.6 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.1 | 1.8 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 0.9 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.1 | 0.6 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.1 | 0.6 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.1 | 0.5 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.1 | 0.3 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.1 | 1.7 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 1.3 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 2.3 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 0.3 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.1 | 2.8 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.1 | 0.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.1 | 0.2 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 1.1 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.1 | 7.0 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 1.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 2.8 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 1.0 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 6.1 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 0.1 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.1 | 0.5 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 0.2 | GO:0005592 | collagen type XI trimer(GO:0005592) |
| 0.1 | 5.2 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 3.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.5 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.0 | 6.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.0 | 0.9 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 8.5 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 5.9 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.3 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 2.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 5.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 2.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.4 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 1.8 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 5.2 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 5.7 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 4.7 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 0.2 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.5 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.0 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.9 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 1.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.3 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.0 | 1.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.6 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.4 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 1.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 8.5 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 9.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 2.1 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.7 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 0.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 2.2 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 1.4 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 1.2 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.5 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.9 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 1.6 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 6.0 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 1.3 | 6.4 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 1.3 | 5.1 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 1.0 | 2.9 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.9 | 5.6 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.8 | 3.9 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.7 | 2.2 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.7 | 2.9 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.7 | 2.8 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 0.7 | 2.6 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
| 0.6 | 1.8 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.6 | 5.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.6 | 1.7 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.6 | 4.5 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 0.5 | 4.0 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.5 | 2.5 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.5 | 6.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.5 | 1.4 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.4 | 3.6 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.4 | 6.1 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.4 | 2.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.4 | 1.7 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.4 | 4.9 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.4 | 4.1 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.4 | 1.2 | GO:0004651 | polynucleotide 5'-phosphatase activity(GO:0004651) |
| 0.4 | 11.7 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.4 | 1.2 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.4 | 3.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.4 | 1.1 | GO:0001034 | RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) |
| 0.4 | 2.1 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.3 | 1.7 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.3 | 2.2 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.3 | 1.6 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 0.3 | 0.9 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.3 | 1.2 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.3 | 1.4 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.3 | 0.8 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 0.3 | 2.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.3 | 1.9 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.3 | 2.1 | GO:0038064 | collagen receptor activity(GO:0038064) |
| 0.3 | 2.8 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.3 | 4.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.2 | 2.3 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.2 | 5.4 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.2 | 2.5 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.2 | 0.6 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.2 | 0.6 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 0.2 | 4.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.2 | 4.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 2.5 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.2 | 1.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.2 | 0.5 | GO:0047322 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405) |
| 0.2 | 1.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.2 | 0.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.2 | 2.5 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.2 | 1.0 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.2 | 2.6 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.2 | 0.8 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.2 | 3.2 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.2 | 3.0 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.2 | 0.8 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.2 | 2.1 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.1 | 9.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 1.3 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.1 | 0.6 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.1 | 1.4 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 0.4 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.1 | 1.2 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 0.4 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 2.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 0.6 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.1 | 0.5 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.1 | 2.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 1.4 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.1 | 1.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 0.5 | GO:0004420 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 0.1 | 2.1 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 0.4 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) |
| 0.1 | 1.8 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 3.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 0.4 | GO:0052591 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.1 | 6.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 3.2 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 0.5 | GO:0016933 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 0.1 | 0.5 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 0.3 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.1 | 5.8 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 4.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.3 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.1 | 0.6 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.1 | 1.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.5 | GO:0022821 | calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821) |
| 0.1 | 1.8 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 1.4 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.1 | 0.2 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.1 | 0.3 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 1.8 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.1 | 2.6 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
| 0.1 | 0.9 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 1.7 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.1 | 1.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 2.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 1.0 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 1.2 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 2.7 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 2.6 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 0.6 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.1 | 0.7 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.1 | 0.7 | GO:0003720 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.1 | 0.3 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.1 | 1.3 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.1 | 0.7 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 7.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 1.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 4.2 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 0.5 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.1 | 2.1 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.4 | GO:0031705 | bombesin receptor binding(GO:0031705) |
| 0.0 | 0.8 | GO:0016004 | phospholipase activator activity(GO:0016004) |
| 0.0 | 3.9 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.2 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.0 | 3.5 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.1 | GO:0016295 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 0.0 | 0.5 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.0 | 2.1 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.9 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 1.8 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 6.8 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.0 | 1.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 0.3 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988) |
| 0.0 | 0.2 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.0 | 0.3 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.0 | 0.8 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 1.3 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.4 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.2 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.0 | 2.2 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 1.4 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.2 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.0 | 0.9 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.0 | 2.1 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.6 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 1.3 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 0.7 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.3 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 0.2 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 1.2 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 2.8 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.9 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 1.3 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
| 0.0 | 0.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.4 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 3.0 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 5.2 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 2.0 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.1 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.0 | 0.7 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.1 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.0 | 2.4 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 0.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 1.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.3 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.0 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 0.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 2.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 0.2 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 1.1 | GO:1901981 | phosphatidylinositol phosphate binding(GO:1901981) |
| 0.0 | 1.0 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.0 | 0.8 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 1.1 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.8 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.6 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.1 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.4 | 1.7 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.4 | 23.5 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.2 | 1.9 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 7.0 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 2.4 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 2.1 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 1.3 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.8 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 4.9 | PID MYC PATHWAY | C-MYC pathway |
| 0.1 | 2.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 5.3 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 1.1 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 3.0 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 3.8 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 2.9 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 0.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 5.3 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 2.5 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 1.7 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 2.3 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 2.9 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 2.1 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 4.9 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 2.0 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 2.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.5 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.5 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 6.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.6 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.6 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.9 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 2.0 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.6 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.4 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 0.5 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 1.2 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.4 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.5 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.0 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.1 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.2 | PID ALK2 PATHWAY | ALK2 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 1.1 | REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR | Genes involved in Downstream signaling of activated FGFR |
| 0.8 | 18.1 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.4 | 6.5 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.4 | 1.2 | REACTOME MRNA CAPPING | Genes involved in mRNA Capping |
| 0.2 | 9.4 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 4.5 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.2 | 5.0 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.2 | 2.6 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.2 | 5.1 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.2 | 2.8 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.2 | 2.5 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.2 | 5.1 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 1.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.1 | 2.1 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.1 | 3.1 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.1 | 3.6 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.1 | 2.1 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 2.2 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 3.0 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 4.9 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 2.9 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 2.4 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 2.3 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 0.4 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.1 | 7.7 | REACTOME RNA POL II PRE TRANSCRIPTION EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.1 | 0.8 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 3.1 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 2.3 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 3.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 2.5 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 3.6 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 4.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 0.5 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 1.4 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 2.8 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.1 | 2.7 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 2.5 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 2.1 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 2.3 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 0.6 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.1 | 2.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.4 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.1 | 0.5 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.1 | 1.2 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 2.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 1.9 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.6 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.6 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 2.2 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.6 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 2.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.9 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.7 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 1.4 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 1.2 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 3.0 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.5 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.4 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.0 | 0.9 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 2.2 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 1.4 | REACTOME ION CHANNEL TRANSPORT | Genes involved in Ion channel transport |
| 0.0 | 1.2 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.7 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 3.7 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.3 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.2 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.0 | 0.4 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 1.3 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.5 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.6 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |