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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UGCAUAG

Z-value: 4.63

Motif logo

logo of

miRNA associated with seed UGCAUAG

NamemiRBASE accession
hsa-miR-153-3p
MIMAT0000439

Activity profile of UGCAUAG motif

Sorted Z-values of UGCAUAG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UGCAUAG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_10218808 30.20 ENST00000254976.7
ENST00000304886.6
SNAP25
synaptosome associated protein 25
chr8_+_24914942 24.63 ENST00000433454.3
NEFM
neurofilament medium
chr3_+_111998739 20.23 ENST00000393917.6
ENST00000273368.8
TAGLN3
transgelin 3
chr5_+_141359970 19.76 ENST00000522605.2
ENST00000622527.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr5_+_141489066 18.50 ENST00000252087.3
PCDHGC5
protocadherin gamma subfamily C, 5
chr5_+_141382702 18.29 ENST00000617050.1
ENST00000518325.2
PCDHGA7
protocadherin gamma subfamily A, 7
chr5_+_141350081 16.95 ENST00000523390.2
ENST00000611598.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr10_-_15371225 16.76 ENST00000378116.9
FAM171A1
family with sequence similarity 171 member A1
chr5_+_141370236 16.31 ENST00000576222.2
ENST00000618934.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr12_+_78864768 16.20 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr5_+_141417659 16.06 ENST00000398594.4
PCDHGB7
protocadherin gamma subfamily B, 7
chr5_+_141392616 15.45 ENST00000398604.3
PCDHGA8
protocadherin gamma subfamily A, 8
chr10_-_79445617 15.06 ENST00000372336.4
ZCCHC24
zinc finger CCHC-type containing 24
chr5_+_141364153 14.78 ENST00000518069.2
PCDHGA5
protocadherin gamma subfamily A, 5
chr3_+_49554436 14.40 ENST00000296452.5
BSN
bassoon presynaptic cytomatrix protein
chr5_+_141373878 14.37 ENST00000517434.3
ENST00000610583.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr5_+_141484997 13.82 ENST00000617094.1
ENST00000306593.2
ENST00000610539.1
ENST00000618371.4
PCDHGC4
protocadherin gamma subfamily C, 4
chr11_-_18634332 13.28 ENST00000336349.6
SPTY2D1
SPT2 chromatin protein domain containing 1
chr8_+_79611036 13.27 ENST00000220876.12
ENST00000518111.5
STMN2
stathmin 2
chr1_+_160205374 12.82 ENST00000368077.5
ENST00000360472.9
PEA15
proliferation and apoptosis adaptor protein 15
chr15_+_74995520 12.57 ENST00000562327.5
ENST00000568018.5
ENST00000425597.8
ENST00000562212.5
ENST00000567920.5
ENST00000566872.5
ENST00000361900.10
SCAMP5
secretory carrier membrane protein 5
chr17_-_39607876 12.47 ENST00000302584.5
NEUROD2
neuronal differentiation 2
chr5_+_141430499 12.31 ENST00000252085.4
PCDHGA12
protocadherin gamma subfamily A, 12
chr5_+_141355003 11.65 ENST00000571252.3
ENST00000612927.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr5_+_141387698 11.53 ENST00000615384.1
ENST00000519479.2
PCDHGB4
protocadherin gamma subfamily B, 4
chr4_-_5893075 11.46 ENST00000324989.12
CRMP1
collapsin response mediator protein 1
chr10_-_60389833 11.19 ENST00000280772.7
ANK3
ankyrin 3
chr16_+_66880503 11.13 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr15_-_73633310 10.94 ENST00000345330.9
NPTN
neuroplastin
chr5_+_140966466 10.72 ENST00000615316.1
ENST00000289269.7
PCDHAC2
protocadherin alpha subfamily C, 2
chr8_-_65842051 10.56 ENST00000401827.8
PDE7A
phosphodiesterase 7A
chr11_+_121452291 9.96 ENST00000260197.12
SORL1
sortilin related receptor 1
chr5_+_141338753 9.57 ENST00000528330.2
ENST00000394576.3
PCDHGA2
protocadherin gamma subfamily A, 2
chr20_+_9514562 9.42 ENST00000246070.3
LAMP5
lysosomal associated membrane protein family member 5
chr5_+_140848360 9.41 ENST00000532602.2
PCDHA9
protocadherin alpha 9
chr4_-_101347471 9.04 ENST00000323055.10
ENST00000512215.5
PPP3CA
protein phosphatase 3 catalytic subunit alpha
chr5_+_140868945 8.94 ENST00000398640.7
PCDHA11
protocadherin alpha 11
chr5_+_140841183 8.83 ENST00000378123.4
ENST00000531613.2
PCDHA8
protocadherin alpha 8
chr20_+_1266263 8.83 ENST00000649598.1
ENST00000381867.6
ENST00000381873.7
SNPH
syntaphilin
chr13_-_36131286 8.68 ENST00000255448.8
ENST00000379892.4
DCLK1
doublecortin like kinase 1
chrX_+_135985416 8.54 ENST00000370698.7
ENST00000627534.2
ENST00000370695.8
ENST00000630721.3
ENST00000678163.1
SLC9A6
solute carrier family 9 member A6
chr7_+_69598465 8.46 ENST00000342771.10
AUTS2
activator of transcription and developmental regulator AUTS2
chr1_+_50108856 8.38 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAVL4
ELAV like RNA binding protein 4
chr12_-_42144823 8.29 ENST00000398675.8
GXYLT1
glucoside xylosyltransferase 1
chr5_+_140875299 8.05 ENST00000613593.1
ENST00000398631.3
PCDHA12
protocadherin alpha 12
chr11_-_113875555 8.04 ENST00000003302.8
ENST00000545540.5
USP28
ubiquitin specific peptidase 28
chr13_-_109786567 7.95 ENST00000375856.5
IRS2
insulin receptor substrate 2
chr6_+_44270434 7.94 ENST00000451188.7
TMEM151B
transmembrane protein 151B
chr18_-_55588184 7.33 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
TCF4
transcription factor 4
chr11_-_73598183 7.33 ENST00000064778.8
FAM168A
family with sequence similarity 168 member A
chr17_-_8163522 7.32 ENST00000404970.3
VAMP2
vesicle associated membrane protein 2
chr21_-_26170654 7.21 ENST00000439274.6
ENST00000358918.7
ENST00000354192.7
ENST00000348990.9
ENST00000346798.8
ENST00000357903.7
APP
amyloid beta precursor protein
chr8_+_38176802 7.09 ENST00000287322.5
BAG4
BAG cochaperone 4
chr4_+_71339014 7.03 ENST00000340595.4
SLC4A4
solute carrier family 4 member 4
chr14_+_85530127 6.97 ENST00000330753.6
FLRT2
fibronectin leucine rich transmembrane protein 2
chr13_+_34942263 6.85 ENST00000379939.7
ENST00000400445.7
NBEA
neurobeachin
chr1_+_159171607 6.80 ENST00000368124.8
ENST00000368125.9
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr1_-_94927079 6.71 ENST00000370206.9
ENST00000394202.8
CNN3
calponin 3
chr20_+_56358938 6.66 ENST00000371384.4
ENST00000437418.1
FAM210B
family with sequence similarity 210 member B
chr16_+_27550127 6.65 ENST00000261588.9
KATNIP
katanin interacting protein
chr1_+_99264473 6.56 ENST00000370185.9
PLPPR4
phospholipid phosphatase related 4
chr20_-_49278034 6.54 ENST00000371744.5
ENST00000396105.6
ENST00000371752.5
ZNFX1
zinc finger NFX1-type containing 1
chr7_+_139231225 6.53 ENST00000473989.8
UBN2
ubinuclein 2
chr5_+_141343818 6.43 ENST00000619750.1
ENST00000253812.8
PCDHGA3
protocadherin gamma subfamily A, 3
chr9_-_23821275 6.33 ENST00000380110.8
ELAVL2
ELAV like RNA binding protein 2
chr19_+_18683656 6.17 ENST00000338797.10
ENST00000321949.13
CRTC1
CREB regulated transcription coactivator 1
chr10_-_20897288 5.95 ENST00000377122.9
NEBL
nebulette
chrX_-_47619850 5.88 ENST00000295987.13
ENST00000340666.5
SYN1
synapsin I
chr12_+_64780465 5.87 ENST00000542120.6
TBC1D30
TBC1 domain family member 30
chr4_-_89837106 5.75 ENST00000394986.5
ENST00000394991.8
ENST00000506244.5
ENST00000394989.6
ENST00000673902.1
ENST00000674129.1
SNCA
synuclein alpha
chr9_-_10612966 5.61 ENST00000381196.9
PTPRD
protein tyrosine phosphatase receptor type D
chr14_-_77377046 5.54 ENST00000216468.8
TMED8
transmembrane p24 trafficking protein family member 8
chr6_+_41072939 5.52 ENST00000341376.11
ENST00000353205.5
NFYA
nuclear transcription factor Y subunit alpha
chr7_-_124765753 5.39 ENST00000303921.3
GPR37
G protein-coupled receptor 37
chr1_+_33081145 5.30 ENST00000294517.11
ENST00000373443.7
AZIN2
antizyme inhibitor 2
chr2_+_206443496 5.19 ENST00000264377.8
ADAM23
ADAM metallopeptidase domain 23
chr17_-_43778937 5.17 ENST00000226004.8
DUSP3
dual specificity phosphatase 3
chr5_+_140926299 5.12 ENST00000253807.3
ENST00000409700.4
PCDHAC1
protocadherin alpha subfamily C, 1
chr5_+_140834230 5.09 ENST00000356878.5
ENST00000525929.2
PCDHA7
protocadherin alpha 7
chr22_+_29073024 5.03 ENST00000400335.9
KREMEN1
kringle containing transmembrane protein 1
chr19_+_48619489 4.90 ENST00000245222.9
SPHK2
sphingosine kinase 2
chr12_-_54280087 4.89 ENST00000209875.9
CBX5
chromobox 5
chr5_+_140786136 4.86 ENST00000378133.4
ENST00000504120.4
PCDHA1
protocadherin alpha 1
chr1_+_52142044 4.79 ENST00000287727.8
ENST00000371591.2
ZFYVE9
zinc finger FYVE-type containing 9
chrX_+_44873169 4.78 ENST00000675577.1
ENST00000674867.1
ENST00000674586.1
ENST00000382899.9
ENST00000536777.6
ENST00000543216.6
ENST00000377967.9
ENST00000611820.5
KDM6A
lysine demethylase 6A
chr10_+_135067 4.73 ENST00000381591.5
ZMYND11
zinc finger MYND-type containing 11
chr15_-_42548763 4.70 ENST00000563454.5
ENST00000397130.8
ENST00000570160.1
ENST00000323443.6
LRRC57
leucine rich repeat containing 57
chr5_+_141402764 4.59 ENST00000573521.2
ENST00000616887.1
PCDHGA9
protocadherin gamma subfamily A, 9
chr2_-_221572272 4.57 ENST00000409854.5
ENST00000443796.5
ENST00000281821.7
EPHA4
EPH receptor A4
chr5_+_140806929 4.56 ENST00000378125.4
ENST00000618834.1
ENST00000530339.2
ENST00000512229.6
ENST00000672575.1
PCDHA4
protocadherin alpha 4
chr17_-_35089212 4.51 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr12_-_48716675 4.50 ENST00000261900.8
ENST00000640148.1
CCNT1
cyclin T1
chr14_+_35046238 4.50 ENST00000280987.9
FAM177A1
family with sequence similarity 177 member A1
chr9_-_14314067 4.42 ENST00000397575.7
NFIB
nuclear factor I B
chr2_-_47570905 4.39 ENST00000327876.5
KCNK12
potassium two pore domain channel subfamily K member 12
chr15_-_52569197 4.36 ENST00000563277.5
ENST00000566423.5
ARPP19
cAMP regulated phosphoprotein 19
chrX_-_33128360 4.29 ENST00000378677.6
DMD
dystrophin
chr15_-_78131433 4.15 ENST00000557846.5
ENST00000258930.8
CIB2
calcium and integrin binding family member 2
chr12_-_121580954 4.14 ENST00000536437.5
ENST00000611216.4
ENST00000538046.6
ENST00000377071.9
KDM2B
lysine demethylase 2B
chr12_+_55019967 4.11 ENST00000242994.4
NEUROD4
neuronal differentiation 4
chr7_+_43112593 4.07 ENST00000453890.5
ENST00000395891.7
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr21_+_36320183 4.04 ENST00000400485.6
MORC3
MORC family CW-type zinc finger 3
chr2_-_148020689 4.03 ENST00000457954.5
ENST00000392857.10
ENST00000540442.5
ENST00000535373.5
ORC4
origin recognition complex subunit 4
chr3_-_115071333 3.88 ENST00000462705.5
ZBTB20
zinc finger and BTB domain containing 20
chr10_-_73874502 3.86 ENST00000372765.5
ENST00000351293.7
ENST00000441192.2
ENST00000423381.6
CAMK2G
calcium/calmodulin dependent protein kinase II gamma
chr1_+_95117324 3.75 ENST00000370203.9
ENST00000456991.5
TLCD4
TLC domain containing 4
chr4_+_2843820 3.75 ENST00000683351.1
ENST00000398125.5
ENST00000264758.11
ENST00000446856.5
ENST00000511797.5
ENST00000513328.6
ENST00000508277.5
ENST00000503455.6
ADD1
adducin 1
chr12_+_111034136 3.69 ENST00000261726.11
CUX2
cut like homeobox 2
chrX_+_10156960 3.66 ENST00000380833.9
CLCN4
chloride voltage-gated channel 4
chr15_+_33310946 3.61 ENST00000415757.7
ENST00000634891.2
ENST00000389232.9
ENST00000622037.1
RYR3
ryanodine receptor 3
chr7_-_72336995 3.59 ENST00000329008.9
CALN1
calneuron 1
chr19_-_1174227 3.59 ENST00000587024.5
ENST00000361757.8
SBNO2
strawberry notch homolog 2
chr9_-_127980976 3.58 ENST00000373095.6
FAM102A
family with sequence similarity 102 member A
chr8_+_78666056 3.57 ENST00000263849.9
ZC2HC1A
zinc finger C2HC-type containing 1A
chr5_+_140114085 3.57 ENST00000331327.5
PURA
purine rich element binding protein A
chr2_+_26848093 3.53 ENST00000288699.11
DPYSL5
dihydropyrimidinase like 5
chr5_+_68215738 3.51 ENST00000521381.6
ENST00000521657.5
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr5_+_141412979 3.46 ENST00000612503.1
ENST00000398610.3
PCDHGA10
protocadherin gamma subfamily A, 10
chr5_+_140882116 3.41 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
PCDHA13
protocadherin alpha 13
chr5_+_141421020 3.37 ENST00000622044.1
ENST00000398587.7
PCDHGA11
protocadherin gamma subfamily A, 11
chr1_-_147172456 3.35 ENST00000254101.4
PRKAB2
protein kinase AMP-activated non-catalytic subunit beta 2
chr1_+_171841466 3.33 ENST00000367733.6
ENST00000627582.3
ENST00000355305.9
ENST00000367731.5
DNM3
dynamin 3
chr5_+_141408032 3.33 ENST00000520790.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr13_-_52848632 3.30 ENST00000377942.7
ENST00000338862.5
PCDH8
protocadherin 8
chr2_+_23940411 3.27 ENST00000309033.5
UBXN2A
UBX domain protein 2A
chr4_+_88592426 3.26 ENST00000431413.5
ENST00000402738.6
ENST00000422770.5
ENST00000407637.5
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr2_-_131093378 3.21 ENST00000409185.5
ENST00000389915.4
FAM168B
family with sequence similarity 168 member B
chr20_+_49982969 3.20 ENST00000244050.3
SNAI1
snail family transcriptional repressor 1
chr22_-_28679865 3.17 ENST00000397906.6
TTC28
tetratricopeptide repeat domain 28
chr12_+_119593758 3.16 ENST00000426426.3
TMEM233
transmembrane protein 233
chr21_-_36990198 3.15 ENST00000427746.1
ENST00000336648.8
HLCS
holocarboxylase synthetase
chr9_+_122941003 3.11 ENST00000373647.9
ENST00000402311.5
RABGAP1
RAB GTPase activating protein 1
chr4_-_42657085 3.08 ENST00000264449.14
ENST00000510289.1
ENST00000381668.9
ATP8A1
ATPase phospholipid transporting 8A1
chr20_+_8132138 3.05 ENST00000378641.7
ENST00000338037.11
ENST00000629992.2
PLCB1
phospholipase C beta 1
chr5_+_141475928 3.03 ENST00000611950.1
ENST00000308177.5
ENST00000617641.4
ENST00000621008.1
ENST00000617222.4
PCDHGC3
protocadherin gamma subfamily C, 3
chr12_+_113221429 3.02 ENST00000551096.5
ENST00000551099.5
ENST00000552897.5
ENST00000550785.5
ENST00000549279.1
ENST00000335509.11
TPCN1
two pore segment channel 1
chr5_+_141330494 2.97 ENST00000517417.3
ENST00000378105.4
PCDHGA1
protocadherin gamma subfamily A, 1
chr5_-_180353317 2.92 ENST00000253778.13
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr11_+_125164743 2.82 ENST00000298282.14
PKNOX2
PBX/knotted 1 homeobox 2
chr18_+_13218769 2.81 ENST00000677055.1
ENST00000399848.7
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr15_+_31326807 2.77 ENST00000307145.4
KLF13
Kruppel like factor 13
chr12_+_4909895 2.71 ENST00000638821.1
ENST00000382545.5
ENSG00000256654.4
KCNA1
novel transcript, sense overlapping KCNA1
potassium voltage-gated channel subfamily A member 1
chr15_-_29822418 2.68 ENST00000614355.5
ENST00000495972.6
ENST00000346128.10
TJP1
tight junction protein 1
chr2_-_206086057 2.65 ENST00000403263.6
INO80D
INO80 complex subunit D
chr20_-_49482645 2.60 ENST00000371741.6
KCNB1
potassium voltage-gated channel subfamily B member 1
chr11_+_33257265 2.58 ENST00000303296.9
ENST00000379016.7
HIPK3
homeodomain interacting protein kinase 3
chr5_+_149730260 2.58 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARGC1B
PPARG coactivator 1 beta
chr6_-_34696733 2.57 ENST00000374023.8
ILRUN
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr8_+_106657836 2.54 ENST00000312046.10
OXR1
oxidation resistance 1
chr6_+_163414637 2.54 ENST00000453779.6
ENST00000275262.11
ENST00000392127.6
QKI
QKI, KH domain containing RNA binding
chr22_-_38755458 2.49 ENST00000405510.5
ENST00000433561.5
SUN2
Sad1 and UNC84 domain containing 2
chr5_-_59893718 2.42 ENST00000340635.11
PDE4D
phosphodiesterase 4D
chr2_-_152099023 2.37 ENST00000201943.10
ENST00000427385.6
ENST00000539935.7
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr3_-_123585013 2.34 ENST00000383657.10
HACD2
3-hydroxyacyl-CoA dehydratase 2
chr17_-_33293247 2.32 ENST00000225823.7
ASIC2
acid sensing ion channel subunit 2
chr4_-_148444674 2.31 ENST00000344721.8
NR3C2
nuclear receptor subfamily 3 group C member 2
chr2_-_27263034 2.28 ENST00000233535.9
SLC30A3
solute carrier family 30 member 3
chr10_-_123008784 2.26 ENST00000368886.10
IKZF5
IKAROS family zinc finger 5
chr4_-_170003738 2.23 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibril associated protein 3 like
chr2_+_73984902 2.23 ENST00000409262.8
TET3
tet methylcytosine dioxygenase 3
chr8_+_28494190 2.21 ENST00000537916.2
ENST00000240093.8
ENST00000523546.1
FZD3
frizzled class receptor 3
chr1_-_236281951 2.19 ENST00000354619.10
ERO1B
endoplasmic reticulum oxidoreductase 1 beta
chr6_-_89819699 2.18 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
MDN1
midasin AAA ATPase 1
chr10_-_118046922 2.17 ENST00000355624.8
RAB11FIP2
RAB11 family interacting protein 2
chr14_-_93333015 2.15 ENST00000334746.10
ENST00000554565.5
ENST00000298896.7
BTBD7
BTB domain containing 7
chr11_+_26332117 2.12 ENST00000531646.1
ENST00000256737.8
ANO3
anoctamin 3
chr8_-_132481057 2.10 ENST00000388996.10
KCNQ3
potassium voltage-gated channel subfamily Q member 3
chr1_+_202348687 2.10 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chr21_-_41926680 2.09 ENST00000329623.11
C2CD2
C2 calcium dependent domain containing 2
chr7_-_6272575 2.06 ENST00000350796.8
CYTH3
cytohesin 3
chr11_+_118530990 2.05 ENST00000411589.6
ENST00000359862.8
ENST00000442938.6
TMEM25
transmembrane protein 25
chr6_+_101398788 2.03 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr13_+_113297217 2.00 ENST00000332556.5
LAMP1
lysosomal associated membrane protein 1
chr7_-_100479142 1.99 ENST00000300181.7
ENST00000393991.5
TSC22D4
TSC22 domain family member 4
chrX_-_54357993 1.96 ENST00000375169.7
ENST00000354646.6
WNK3
WNK lysine deficient protein kinase 3
chr19_-_10928585 1.88 ENST00000590329.5
ENST00000587943.5
ENST00000586748.6
ENST00000585858.1
ENST00000586575.5
ENST00000253031.6
YIPF2
Yip1 domain family member 2
chr8_-_115668966 1.87 ENST00000395715.8
TRPS1
transcriptional repressor GATA binding 1
chr1_-_57424014 1.83 ENST00000371230.1
ENST00000371236.7
DAB1
DAB adaptor protein 1
chr16_+_23557714 1.83 ENST00000567212.5
ENST00000567264.1
ENST00000395878.8
UBFD1
ubiquitin family domain containing 1
chr1_+_212950572 1.80 ENST00000366968.8
ENST00000490792.1
ENST00000366964.7
VASH2
vasohibin 2
chr6_+_116280098 1.78 ENST00000643175.1
ENST00000452085.7
DSE
dermatan sulfate epimerase
chr10_+_79068955 1.76 ENST00000334512.10
ZMIZ1
zinc finger MIZ-type containing 1
chr1_-_243850070 1.75 ENST00000366539.6
ENST00000672578.1
AKT3
AKT serine/threonine kinase 3
chr3_-_179071742 1.75 ENST00000311417.7
ENST00000652290.1
ZMAT3
zinc finger matrin-type 3
chr2_-_201451446 1.69 ENST00000332624.8
ENST00000430254.1
TRAK2
trafficking kinesin protein 2
chr6_+_116681176 1.69 ENST00000413340.5
ENST00000356348.6
ENST00000368564.7
KPNA5
karyopherin subunit alpha 5
chr10_+_84328625 1.68 ENST00000224756.12
CCSER2
coiled-coil serine rich protein 2
chr15_+_100602519 1.67 ENST00000332783.12
ENST00000558747.5
ENST00000343276.4
ASB7
ankyrin repeat and SOCS box containing 7
chr9_+_105244598 1.65 ENST00000374723.5
ENST00000374724.1
ENST00000374720.8
SLC44A1
solute carrier family 44 member 1
chr5_-_137754327 1.64 ENST00000314940.7
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr11_-_94493798 1.63 ENST00000538923.1
ENST00000540013.5
ENST00000407439.7
ENST00000323929.8
ENST00000393241.8
MRE11
MRE11 homolog, double strand break repair nuclease
chr6_+_169702185 1.63 ENST00000332290.3
C6orf120
chromosome 6 open reading frame 120
chr8_+_37796906 1.57 ENST00000315215.11
ADGRA2
adhesion G protein-coupled receptor A2
chr2_-_171894227 1.54 ENST00000422440.7
SLC25A12
solute carrier family 25 member 12
chr6_+_11537738 1.52 ENST00000379426.2
TMEM170B
transmembrane protein 170B
chr16_-_17470953 1.52 ENST00000261381.7
XYLT1
xylosyltransferase 1
chr15_-_34754989 1.51 ENST00000290374.5
GJD2
gap junction protein delta 2
chr2_-_181680490 1.50 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
CERKL
NEUROD1
ceramide kinase like
neuronal differentiation 1
chr5_-_95961830 1.46 ENST00000513343.1
ENST00000237853.9
ELL2
elongation factor for RNA polymerase II 2
chr3_+_184155310 1.46 ENST00000313143.9
DVL3
dishevelled segment polarity protein 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 33.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
6.2 24.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
5.4 16.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
4.4 13.3 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
4.4 13.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
3.8 11.5 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
3.3 10.0 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
3.3 13.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
3.1 12.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
2.8 8.5 GO:0098582 innate vocalization behavior(GO:0098582)
2.8 11.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.4 7.3 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
2.3 9.0 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
2.1 6.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.9 327.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.8 5.3 GO:0015847 putrescine transport(GO:0015847)
1.5 4.6 GO:1905244 fasciculation of motor neuron axon(GO:0097156) regulation of modification of synaptic structure(GO:1905244)
1.4 7.2 GO:0016199 axon midline choice point recognition(GO:0016199)
1.4 4.1 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
1.3 8.0 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
1.2 4.9 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
1.0 3.1 GO:0007343 egg activation(GO:0007343)
1.0 5.7 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.9 5.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.9 7.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.9 6.3 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.9 4.5 GO:2001271 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.9 8.5 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.8 3.2 GO:0009305 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.8 7.1 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.7 2.2 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.7 2.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.7 5.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.7 4.8 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.7 12.8 GO:0046325 negative regulation of glucose import(GO:0046325)
0.7 2.0 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.7 12.0 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
0.6 3.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6 6.3 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.6 1.8 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.6 3.6 GO:0071105 response to interleukin-11(GO:0071105)
0.6 1.7 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.5 2.7 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.5 3.7 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 1.6 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.5 2.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.5 3.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.5 1.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.5 2.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.5 2.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.5 2.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) sensory perception of sour taste(GO:0050915)
0.5 5.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.5 4.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.4 2.2 GO:0030070 insulin processing(GO:0030070)
0.4 1.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4 4.4 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 5.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.4 4.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 6.3 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.3 4.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 6.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.3 0.9 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.3 1.8 GO:0007296 vitellogenesis(GO:0007296)
0.3 3.5 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.3 2.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.3 0.9 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.3 2.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.3 3.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 0.5 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.3 11.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 1.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 2.0 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.5 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 2.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.2 7.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.2 1.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 1.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 4.2 GO:0071318 cellular response to ATP(GO:0071318)
0.2 2.8 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 8.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 0.4 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.2 1.6 GO:0042426 choline catabolic process(GO:0042426)
0.2 2.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 2.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 5.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 2.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 2.9 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 4.9 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 0.9 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.2 0.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 6.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.2 1.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 3.7 GO:0007614 short-term memory(GO:0007614)
0.2 0.7 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 2.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.2 6.1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.2 3.4 GO:0006853 carnitine shuttle(GO:0006853)
0.1 4.0 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 7.0 GO:0050919 negative chemotaxis(GO:0050919)
0.1 2.3 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 7.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 2.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 3.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 1.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 1.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.0 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 8.0 GO:0034644 cellular response to UV(GO:0034644)
0.1 1.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 2.0 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 5.5 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 2.3 GO:0009299 mRNA transcription(GO:0009299)
0.1 2.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 2.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012) establishment of epithelial cell polarity(GO:0090162)
0.1 3.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.1 2.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 2.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 2.2 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.8 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 3.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.7 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.4 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 1.9 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.5 GO:0060004 reflex(GO:0060004)
0.0 1.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.7 GO:0014002 astrocyte development(GO:0014002)
0.0 0.5 GO:0032648 regulation of interferon-beta production(GO:0032648)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713) Sertoli cell proliferation(GO:0060011)
0.0 0.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.3 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 1.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 2.6 GO:0006310 DNA recombination(GO:0006310)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 37.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
4.4 13.3 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
3.2 16.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.7 8.5 GO:0044308 axonal spine(GO:0044308)
1.6 24.6 GO:0097418 neurofibrillary tangle(GO:0097418)
1.6 9.4 GO:0032584 growth cone membrane(GO:0032584)
1.1 3.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.9 17.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.9 3.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.8 10.9 GO:0060077 inhibitory synapse(GO:0060077)
0.8 9.0 GO:0005955 calcineurin complex(GO:0005955)
0.7 4.2 GO:0032437 cuticular plate(GO:0032437)
0.5 11.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 3.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.4 2.2 GO:0001940 male pronucleus(GO:0001940)
0.4 4.3 GO:0016013 syntrophin complex(GO:0016013)
0.3 3.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 3.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 5.3 GO:0010369 chromocenter(GO:0010369)
0.3 1.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.0 GO:0048179 activin receptor complex(GO:0048179)
0.2 2.0 GO:0032010 phagolysosome(GO:0032010)
0.2 0.9 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 4.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 4.9 GO:0044295 axonal growth cone(GO:0044295)
0.2 3.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 2.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 2.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 6.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 16.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 4.2 GO:0005921 gap junction(GO:0005921)
0.2 3.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 0.8 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.2 5.2 GO:0001772 immunological synapse(GO:0001772)
0.2 7.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 345.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 8.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.6 GO:0030870 Mre11 complex(GO:0030870)
0.1 5.9 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.3 GO:0070449 elongin complex(GO:0070449)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.3 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 6.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 33.7 GO:0043025 neuronal cell body(GO:0043025)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 6.8 GO:0043235 receptor complex(GO:0043235)
0.1 2.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 7.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 5.9 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 2.1 GO:0031672 A band(GO:0031672)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 3.2 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.5 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 16.2 GO:0030348 syntaxin-3 binding(GO:0030348)
3.0 12.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.2 10.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.8 5.4 GO:0036505 prosaposin receptor activity(GO:0036505)
1.8 5.3 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.5 46.3 GO:0017075 syntaxin-1 binding(GO:0017075)
1.4 8.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.3 13.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.0 9.0 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
1.0 3.9 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
1.0 5.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.9 3.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.9 8.5 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.8 3.2 GO:0018271 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.8 2.3 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.8 17.4 GO:0031005 filamin binding(GO:0031005)
0.7 2.9 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.7 3.6 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.7 7.2 GO:0051425 PTB domain binding(GO:0051425)
0.7 2.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.7 4.9 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.6 10.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.6 1.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.6 2.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.5 7.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 4.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.5 19.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 4.6 GO:0042731 PH domain binding(GO:0042731)
0.5 4.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.4 13.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.4 6.6 GO:0042577 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.4 1.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 6.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 1.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.4 3.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.4 7.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 7.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 5.2 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.3 296.1 GO:0005509 calcium ion binding(GO:0005509)
0.3 7.0 GO:0045499 chemorepellent activity(GO:0045499)
0.3 13.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 4.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 2.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 14.0 GO:0070888 E-box binding(GO:0070888)
0.3 15.3 GO:0030507 spectrin binding(GO:0030507)
0.3 6.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 2.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 3.0 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2 1.0 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.2 3.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 9.9 GO:0017091 AU-rich element binding(GO:0017091)
0.2 3.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.9 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.2 4.3 GO:0017166 vinculin binding(GO:0017166)
0.2 1.4 GO:0043426 MRF binding(GO:0043426)
0.2 5.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 2.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 5.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 24.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 0.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 0.9 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.2 1.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 2.5 GO:0043495 protein anchor(GO:0043495)
0.2 2.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 23.0 GO:0051015 actin filament binding(GO:0051015)
0.1 0.7 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.0 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.1 2.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.5 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 3.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 4.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 12.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.7 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.8 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 5.4 GO:0002039 p53 binding(GO:0002039)
0.1 4.1 GO:0019843 rRNA binding(GO:0019843)
0.1 1.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 2.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.0 1.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 3.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 20.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 10.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 5.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 11.9 PID TNF PATHWAY TNF receptor signaling pathway
0.2 6.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.7 ST GAQ PATHWAY G alpha q Pathway
0.1 0.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 4.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 4.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 11.0 PID P73PATHWAY p73 transcription factor network
0.1 9.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 5.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 2.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 2.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 59.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.7 12.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 15.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 7.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 5.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 5.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 13.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 6.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.3 3.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 11.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 8.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 2.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 3.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 3.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 4.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 5.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 4.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 7.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 4.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 4.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 8.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 3.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors