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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UGGCACU

Z-value: 0.48

Motif logo

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miRNA associated with seed UGGCACU

NamemiRBASE accession
hsa-miR-183-5p.2

Activity profile of UGGCACU motif

Sorted Z-values of UGGCACU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UGGCACU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_20486197 11.12 ENST00000375078.4
CAMK2N1
calcium/calmodulin dependent protein kinase II inhibitor 1
chr15_+_66386902 7.07 ENST00000307102.10
MAP2K1
mitogen-activated protein kinase kinase 1
chr4_-_176002332 6.78 ENST00000280187.11
ENST00000512509.5
GPM6A
glycoprotein M6A
chr13_+_26557659 5.91 ENST00000335327.6
ENST00000361042.8
ENST00000671038.1
WASF3
WASP family member 3
chr16_+_56638659 5.67 ENST00000290705.12
MT1A
metallothionein 1A
chr15_-_52569197 4.94 ENST00000563277.5
ENST00000566423.5
ARPP19
cAMP regulated phosphoprotein 19
chrX_-_13938618 4.87 ENST00000454189.6
GPM6B
glycoprotein M6B
chr3_-_15332526 4.86 ENST00000383791.8
SH3BP5
SH3 domain binding protein 5
chr11_-_45665578 4.63 ENST00000308064.7
CHST1
carbohydrate sulfotransferase 1
chr5_+_77210667 4.25 ENST00000264917.10
PDE8B
phosphodiesterase 8B
chr5_+_17217617 4.14 ENST00000322611.4
BASP1
brain abundant membrane attached signal protein 1
chr1_+_99264473 3.90 ENST00000370185.9
PLPPR4
phospholipid phosphatase related 4
chr5_+_102755269 3.86 ENST00000304400.12
ENST00000455264.7
ENST00000684529.1
ENST00000438793.8
ENST00000682882.1
ENST00000682972.1
ENST00000348126.7
ENST00000512073.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr7_-_47582076 3.79 ENST00000311160.14
TNS3
tensin 3
chr3_+_115623502 3.55 ENST00000305124.11
ENST00000393780.3
GAP43
growth associated protein 43
chr1_+_111619751 3.49 ENST00000433097.5
ENST00000369709.3
RAP1A
RAP1A, member of RAS oncogene family
chr2_-_96208815 3.42 ENST00000443962.1
ENST00000337288.10
STARD7
StAR related lipid transfer domain containing 7
chr3_-_18425295 3.38 ENST00000338745.11
ENST00000450898.1
SATB1
SATB homeobox 1
chr17_+_68512379 3.32 ENST00000392711.5
ENST00000585427.5
ENST00000589228.6
ENST00000536854.6
ENST00000588702.5
ENST00000589309.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr6_-_34392627 3.31 ENST00000607016.2
NUDT3
nudix hydrolase 3
chr4_+_77157189 3.27 ENST00000316355.10
ENST00000502280.5
CCNG2
cyclin G2
chr6_-_16761447 3.27 ENST00000244769.8
ENST00000436367.6
ATXN1
ataxin 1
chr11_-_119423162 3.19 ENST00000284240.10
ENST00000524970.5
THY1
Thy-1 cell surface antigen
chr12_-_48957445 2.98 ENST00000541959.5
ENST00000447318.6
ENST00000256682.9
ARF3
ADP ribosylation factor 3
chr17_-_4366616 2.96 ENST00000572484.5
ENST00000396981.7
UBE2G1
ubiquitin conjugating enzyme E2 G1
chr3_-_66500973 2.95 ENST00000383703.3
ENST00000273261.8
LRIG1
leucine rich repeats and immunoglobulin like domains 1
chr20_+_11890723 2.91 ENST00000254977.7
BTBD3
BTB domain containing 3
chr2_+_172735912 2.75 ENST00000409036.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr12_-_92145838 2.75 ENST00000256015.5
BTG1
BTG anti-proliferation factor 1
chr10_-_15371225 2.74 ENST00000378116.9
FAM171A1
family with sequence similarity 171 member A1
chr22_-_38872206 2.72 ENST00000407418.8
ENST00000216083.6
CBX6
chromobox 6
chr20_+_38805686 2.70 ENST00000299824.6
ENST00000373331.2
PPP1R16B
protein phosphatase 1 regulatory subunit 16B
chr3_-_52278620 2.63 ENST00000296490.8
WDR82
WD repeat domain 82
chr4_-_16898619 2.62 ENST00000502640.5
ENST00000304523.10
ENST00000506732.1
LDB2
LIM domain binding 2
chr12_-_76559504 2.61 ENST00000547544.5
ENST00000393249.6
OSBPL8
oxysterol binding protein like 8
chr10_+_1049476 2.59 ENST00000358220.5
WDR37
WD repeat domain 37
chr8_+_122781621 2.58 ENST00000314393.6
ZHX2
zinc fingers and homeoboxes 2
chr19_+_18097763 2.52 ENST00000262811.10
MAST3
microtubule associated serine/threonine kinase 3
chr13_-_75482151 2.46 ENST00000377636.8
TBC1D4
TBC1 domain family member 4
chr5_+_68215738 2.45 ENST00000521381.6
ENST00000521657.5
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr5_+_65926556 2.45 ENST00000380943.6
ENST00000416865.6
ENST00000380935.5
ENST00000284037.10
ERBIN
erbb2 interacting protein
chr14_-_103057509 2.44 ENST00000361246.7
CDC42BPB
CDC42 binding protein kinase beta
chr1_-_54887161 2.39 ENST00000535035.6
ENST00000371269.9
ENST00000436604.2
DHCR24
24-dehydrocholesterol reductase
chr5_-_79512794 2.35 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
HOMER1
homer scaffold protein 1
chrX_+_71533095 2.33 ENST00000373719.8
ENST00000373701.7
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr9_+_4490388 2.31 ENST00000262352.8
SLC1A1
solute carrier family 1 member 1
chr2_+_158456939 2.24 ENST00000389759.8
ENST00000628904.2
ENST00000389757.7
PKP4
plakophilin 4
chr12_-_16608183 2.20 ENST00000354662.5
ENST00000538051.5
LMO3
LIM domain only 3
chr13_+_98142552 2.19 ENST00000595437.5
FARP1
FERM, ARH/RhoGEF and pleckstrin domain protein 1
chr8_+_97644164 2.12 ENST00000336273.8
MTDH
metadherin
chr2_-_44361754 2.11 ENST00000409272.5
ENST00000410081.5
ENST00000541738.5
PREPL
prolyl endopeptidase like
chr2_-_73269483 2.07 ENST00000295133.9
FBXO41
F-box protein 41
chr3_+_169966764 2.04 ENST00000337002.9
ENST00000480708.5
SEC62
SEC62 homolog, preprotein translocation factor
chr8_-_102864155 2.00 ENST00000682725.1
ENST00000337198.10
ENST00000681985.1
ENST00000684566.1
ENST00000683787.1
ENST00000682014.1
ENST00000682969.1
ENST00000684721.1
ENST00000347770.8
AZIN1
antizyme inhibitor 1
chr3_-_56468346 1.96 ENST00000288221.11
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr6_+_68635273 1.95 ENST00000370598.6
ADGRB3
adhesion G protein-coupled receptor B3
chr9_-_137028223 1.93 ENST00000341511.11
ABCA2
ATP binding cassette subfamily A member 2
chr18_-_55588184 1.92 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
TCF4
transcription factor 4
chr7_-_51316754 1.91 ENST00000632460.1
ENST00000441453.5
ENST00000648294.1
ENST00000265136.12
ENST00000395542.6
ENST00000395540.6
COBL
cordon-bleu WH2 repeat protein
chr7_+_44606619 1.90 ENST00000222673.6
ENST00000444676.5
ENST00000631326.2
OGDH
oxoglutarate dehydrogenase
chr8_+_37762579 1.90 ENST00000523358.5
ENST00000523187.5
ENST00000328195.8
PLPBP
pyridoxal phosphate binding protein
chr19_-_14206168 1.88 ENST00000361434.7
ENST00000340736.10
ADGRL1
adhesion G protein-coupled receptor L1
chr8_+_79611036 1.86 ENST00000220876.12
ENST00000518111.5
STMN2
stathmin 2
chr6_+_63572472 1.86 ENST00000370651.7
ENST00000626021.3
ENSG00000285976.2
PTP4A1
novel protein
protein tyrosine phosphatase 4A1
chr3_+_39809602 1.82 ENST00000302541.11
ENST00000396217.7
MYRIP
myosin VIIA and Rab interacting protein
chr10_+_61901678 1.80 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
ARID5B
AT-rich interaction domain 5B
chr3_-_79019444 1.79 ENST00000618833.4
ENST00000436010.6
ENST00000618846.4
ROBO1
roundabout guidance receptor 1
chr14_+_104865256 1.79 ENST00000414716.8
ENST00000556508.5
ENST00000453495.2
CEP170B
centrosomal protein 170B
chr14_-_74084393 1.77 ENST00000350259.8
ENST00000553458.6
ALDH6A1
aldehyde dehydrogenase 6 family member A1
chr1_+_87328860 1.76 ENST00000370544.10
LMO4
LIM domain only 4
chr18_-_5543988 1.71 ENST00000341928.7
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr12_-_54280087 1.70 ENST00000209875.9
CBX5
chromobox 5
chr11_+_114059702 1.70 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
ZBTB16
zinc finger and BTB domain containing 16
chr5_+_140114085 1.51 ENST00000331327.5
PURA
purine rich element binding protein A
chr2_+_113890039 1.51 ENST00000443297.5
ENST00000263238.7
ENST00000415792.5
ACTR3
actin related protein 3
chr13_-_23375431 1.51 ENST00000683270.1
ENST00000684163.1
ENST00000402364.1
ENST00000683367.1
SACS
sacsin molecular chaperone
chr3_+_57227714 1.46 ENST00000288266.8
APPL1
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
chrX_+_65667645 1.46 ENST00000360270.7
MSN
moesin
chr11_+_117178728 1.46 ENST00000532960.5
ENST00000324225.9
SIDT2
SID1 transmembrane family member 2
chr10_+_110871903 1.44 ENST00000280154.12
PDCD4
programmed cell death 4
chr7_+_98617275 1.44 ENST00000265634.4
NPTX2
neuronal pentraxin 2
chr1_+_109249530 1.43 ENST00000271332.4
CELSR2
cadherin EGF LAG seven-pass G-type receptor 2
chr13_-_25287457 1.43 ENST00000381801.6
MTMR6
myotubularin related protein 6
chr16_-_69385968 1.42 ENST00000567296.6
ENST00000254942.8
TERF2
telomeric repeat binding factor 2
chr14_+_57268963 1.42 ENST00000261558.8
AP5M1
adaptor related protein complex 5 subunit mu 1
chr1_+_203626775 1.40 ENST00000367218.7
ATP2B4
ATPase plasma membrane Ca2+ transporting 4
chr8_-_129939694 1.37 ENST00000522250.5
ENST00000522941.5
ENST00000522746.5
ENST00000520204.5
ENST00000519070.5
ENST00000520254.5
ENST00000519824.6
CYRIB
CYFIP related Rac1 interactor B
chr2_-_226799806 1.37 ENST00000305123.6
IRS1
insulin receptor substrate 1
chr9_-_133121228 1.32 ENST00000372050.8
RALGDS
ral guanine nucleotide dissociation stimulator
chr10_+_72273914 1.30 ENST00000681898.1
ENST00000307365.4
DDIT4
DNA damage inducible transcript 4
chr20_-_45910898 1.26 ENST00000372420.5
PLTP
phospholipid transfer protein
chr16_-_10942443 1.23 ENST00000570440.2
ENST00000331808.5
DEXI
Dexi homolog
chr13_-_41132728 1.22 ENST00000379485.2
KBTBD6
kelch repeat and BTB domain containing 6
chr16_-_68448491 1.18 ENST00000561749.1
ENST00000219334.10
SMPD3
sphingomyelin phosphodiesterase 3
chr2_-_100417608 1.16 ENST00000264249.8
CHST10
carbohydrate sulfotransferase 10
chr1_-_77682639 1.15 ENST00000370801.8
ENST00000433749.5
ZZZ3
zinc finger ZZ-type containing 3
chr3_+_138347648 1.11 ENST00000614350.4
ENST00000289104.8
MRAS
muscle RAS oncogene homolog
chr8_-_11868043 1.10 ENST00000676843.1
ENST00000534510.6
ENST00000676825.1
ENST00000678145.1
ENST00000533455.6
ENST00000353047.11
ENST00000677650.1
ENST00000526195.6
ENST00000676691.1
ENST00000678598.1
ENST00000505496.7
ENST00000527215.7
ENST00000345125.8
ENST00000532656.7
ENST00000678067.1
ENST00000453527.7
ENST00000677415.1
ENST00000530640.7
ENST00000677418.1
ENST00000531089.6
ENST00000677544.1
ENST00000676502.1
ENST00000524500.6
ENST00000677873.1
ENST00000678629.1
ENST00000678929.1
ENST00000677819.1
ENST00000678357.1
ENST00000679051.1
ENST00000677082.1
ENST00000531502.6
ENST00000530296.6
ENST00000534636.6
ENST00000534149.6
ENST00000677366.1
ENST00000676755.1
ENST00000679140.1
ENST00000527243.6
ENST00000677047.1
ENST00000678242.1
CTSB
cathepsin B
chrX_-_103688033 1.10 ENST00000434230.5
ENST00000418819.5
ENST00000360458.5
MORF4L2
mortality factor 4 like 2
chrX_+_12975083 1.10 ENST00000451311.7
ENST00000380636.1
TMSB4X
thymosin beta 4 X-linked
chr12_+_76764109 1.07 ENST00000426126.7
ZDHHC17
zinc finger DHHC-type palmitoyltransferase 17
chr3_+_152299392 1.06 ENST00000498502.5
ENST00000545754.5
ENST00000357472.7
ENST00000324196.9
MBNL1
muscleblind like splicing regulator 1
chr8_+_119873710 1.05 ENST00000523492.5
ENST00000286234.6
DEPTOR
DEP domain containing MTOR interacting protein
chr17_+_50095331 1.04 ENST00000503176.6
PDK2
pyruvate dehydrogenase kinase 2
chr6_-_158818225 1.03 ENST00000337147.11
EZR
ezrin
chr9_+_2015335 1.02 ENST00000636559.1
ENST00000349721.8
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_174799895 1.01 ENST00000489615.5
RABGAP1L
RAB GTPase activating protein 1 like
chr5_-_115625972 0.99 ENST00000333314.3
ENST00000456936.4
TMED7-TICAM2
TMED7
TMED7-TICAM2 readthrough
transmembrane p24 trafficking protein 7
chr10_+_132537778 0.98 ENST00000368594.8
INPP5A
inositol polyphosphate-5-phosphatase A
chr1_+_177170916 0.97 ENST00000361539.5
BRINP2
BMP/retinoic acid inducible neural specific 2
chr8_+_42152946 0.94 ENST00000518421.5
ENST00000174653.3
ENST00000396926.8
ENST00000521280.5
ENST00000522288.5
AP3M2
adaptor related protein complex 3 subunit mu 2
chr12_-_25250879 0.94 ENST00000256078.10
ENST00000311936.8
ENST00000556131.1
ENST00000557334.5
KRAS
KRAS proto-oncogene, GTPase
chr20_-_4823597 0.93 ENST00000379400.8
RASSF2
Ras association domain family member 2
chr2_+_218959635 0.93 ENST00000302625.6
CDK5R2
cyclin dependent kinase 5 regulatory subunit 2
chr17_-_39607876 0.91 ENST00000302584.5
NEUROD2
neuronal differentiation 2
chr6_+_87472925 0.88 ENST00000369556.7
ENST00000369557.9
ENST00000369552.9
SLC35A1
solute carrier family 35 member A1
chr5_-_172006817 0.87 ENST00000296933.10
FBXW11
F-box and WD repeat domain containing 11
chr17_+_2796404 0.87 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chrX_-_107716401 0.86 ENST00000486554.1
ENST00000372390.8
TSC22D3
TSC22 domain family member 3
chr19_-_47471886 0.85 ENST00000236877.11
ENST00000597014.1
SLC8A2
solute carrier family 8 member A2
chr19_-_3985451 0.84 ENST00000309311.7
EEF2
eukaryotic translation elongation factor 2
chr1_-_6180265 0.82 ENST00000262450.8
CHD5
chromodomain helicase DNA binding protein 5
chr12_+_27244222 0.82 ENST00000545470.5
ENST00000389032.8
ENST00000540996.5
STK38L
serine/threonine kinase 38 like
chr5_+_134371561 0.82 ENST00000265339.7
ENST00000506787.5
ENST00000507277.1
UBE2B
ubiquitin conjugating enzyme E2 B
chr9_-_10612966 0.81 ENST00000381196.9
PTPRD
protein tyrosine phosphatase receptor type D
chr2_+_20447065 0.81 ENST00000272233.6
RHOB
ras homolog family member B
chr3_+_14125042 0.80 ENST00000306077.5
TMEM43
transmembrane protein 43
chr1_+_23959797 0.77 ENST00000374468.1
ENST00000334351.8
PNRC2
proline rich nuclear receptor coactivator 2
chrX_+_111096136 0.77 ENST00000372007.10
PAK3
p21 (RAC1) activated kinase 3
chr20_-_46406582 0.76 ENST00000450812.5
ENST00000290246.11
ENST00000396391.5
ELMO2
engulfment and cell motility 2
chr1_+_192809031 0.73 ENST00000235382.7
RGS2
regulator of G protein signaling 2
chr11_+_57753243 0.72 ENST00000524630.5
ENST00000529919.5
ENST00000533189.1
CTNND1
catenin delta 1
chr5_+_153490655 0.72 ENST00000518142.5
ENST00000285900.10
GRIA1
glutamate ionotropic receptor AMPA type subunit 1
chr9_-_111484353 0.72 ENST00000338205.9
ENST00000684092.1
ECPAS
Ecm29 proteasome adaptor and scaffold
chr19_+_36140059 0.71 ENST00000246533.8
ENST00000587718.5
ENST00000592483.5
ENST00000590874.5
ENST00000588815.5
CAPNS1
calpain small subunit 1
chr6_-_89819699 0.69 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
MDN1
midasin AAA ATPase 1
chr21_-_14383125 0.69 ENST00000285667.4
HSPA13
heat shock protein family A (Hsp70) member 13
chr9_+_124862098 0.68 ENST00000353214.6
ARPC5L
actin related protein 2/3 complex subunit 5 like
chr14_+_51240205 0.64 ENST00000457354.7
TMX1
thioredoxin related transmembrane protein 1
chr9_-_36276967 0.64 ENST00000396594.8
ENST00000543356.7
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr15_-_64989894 0.64 ENST00000416889.6
ENST00000204566.7
SPG21
SPG21 abhydrolase domain containing, maspardin
chr15_+_78872809 0.63 ENST00000331268.9
MORF4L1
mortality factor 4 like 1
chr6_+_42782020 0.62 ENST00000314073.9
BICRAL
BRD4 interacting chromatin remodeling complex associated protein like
chr11_-_73876674 0.57 ENST00000545127.1
ENST00000537289.1
ENST00000355693.5
COA4
cytochrome c oxidase assembly factor 4 homolog
chr17_-_39197652 0.54 ENST00000394303.8
CACNB1
calcium voltage-gated channel auxiliary subunit beta 1
chr13_-_30464234 0.52 ENST00000399489.5
ENST00000339872.8
HMGB1
high mobility group box 1
chr16_+_8720706 0.51 ENST00000425191.6
ENST00000569156.5
ABAT
4-aminobutyrate aminotransferase
chr1_-_114670018 0.50 ENST00000393274.6
ENST00000393276.7
DENND2C
DENN domain containing 2C
chr2_+_120252837 0.50 ENST00000272519.10
ENST00000631312.2
RALB
RAS like proto-oncogene B
chr2_+_206443496 0.48 ENST00000264377.8
ADAM23
ADAM metallopeptidase domain 23
chr17_+_2593628 0.48 ENST00000397195.10
PAFAH1B1
platelet activating factor acetylhydrolase 1b regulatory subunit 1
chr22_+_23180365 0.47 ENST00000359540.7
ENST00000305877.13
BCR
BCR activator of RhoGEF and GTPase
chr3_+_140941792 0.46 ENST00000446041.6
ENST00000324194.12
ENST00000507429.5
SLC25A36
solute carrier family 25 member 36
chr7_+_87628355 0.46 ENST00000338056.7
ENST00000493037.5
RUNDC3B
RUN domain containing 3B
chr2_+_161416273 0.46 ENST00000389554.8
TBR1
T-box brain transcription factor 1
chr18_+_13218769 0.44 ENST00000677055.1
ENST00000399848.7
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr9_-_14314067 0.44 ENST00000397575.7
NFIB
nuclear factor I B
chr7_+_5190196 0.44 ENST00000401525.7
ENST00000288828.9
ENST00000404704.7
WIPI2
WD repeat domain, phosphoinositide interacting 2
chr1_+_228082660 0.43 ENST00000540651.5
ENST00000272102.10
ARF1
ADP ribosylation factor 1
chr8_+_73008850 0.43 ENST00000679115.1
ENST00000517390.2
ENST00000678860.1
ENST00000678518.1
ENST00000276602.10
ENST00000276603.10
ENST00000518874.6
TERF1
telomeric repeat binding factor 1
chr3_+_107522936 0.41 ENST00000415149.6
ENST00000402543.5
ENST00000325805.13
ENST00000427402.5
BBX
BBX high mobility group box domain containing
chr8_+_143990047 0.40 ENST00000395068.9
ENST00000313269.5
GRINA
glutamate ionotropic receptor NMDA type subunit associated protein 1
chr1_-_38859669 0.39 ENST00000373001.4
RRAGC
Ras related GTP binding C
chr20_-_33674359 0.38 ENST00000606690.5
ENST00000439478.5
ENST00000246190.11
ENST00000375238.8
NECAB3
N-terminal EF-hand calcium binding protein 3
chr14_-_24213446 0.37 ENST00000530611.1
ENST00000347519.12
ENST00000530996.5
ENSG00000254692.1
CHMP4A
novel protein
charged multivesicular body protein 4A
chr17_-_82273681 0.35 ENST00000392334.6
ENST00000314028.10
CSNK1D
casein kinase 1 delta
chr3_+_130850585 0.34 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr16_-_23510389 0.33 ENST00000562117.1
ENST00000567468.5
ENST00000562944.5
ENST00000309859.8
GGA2
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr4_+_76949743 0.32 ENST00000502584.5
ENST00000264893.11
ENST00000510641.5
SEPTIN11
septin 11
chr19_+_11355386 0.31 ENST00000251473.9
ENST00000591329.5
ENST00000586380.5
PLPPR2
phospholipid phosphatase related 2
chr7_-_138002017 0.31 ENST00000452463.5
ENST00000456390.5
ENST00000330387.11
CREB3L2
cAMP responsive element binding protein 3 like 2
chr2_+_32277883 0.31 ENST00000238831.9
YIPF4
Yip1 domain family member 4
chr19_-_32675139 0.31 ENST00000586693.7
ENST00000587352.5
ENST00000306065.9
ENST00000586463.5
ANKRD27
ankyrin repeat domain 27
chr1_+_15847698 0.30 ENST00000375759.8
SPEN
spen family transcriptional repressor
chr3_-_197555950 0.29 ENST00000445160.2
ENST00000392379.6
ENST00000446746.5
ENST00000432819.5
ENST00000441275.5
ENST00000392378.6
BDH1
3-hydroxybutyrate dehydrogenase 1
chr1_-_67833448 0.28 ENST00000370982.4
GNG12
G protein subunit gamma 12
chrX_+_23334841 0.27 ENST00000379361.5
PTCHD1
patched domain containing 1
chr10_-_112446891 0.26 ENST00000369404.3
ENST00000369405.7
ENST00000626395.2
ZDHHC6
zinc finger DHHC-type palmitoyltransferase 6
chr12_+_113185702 0.25 ENST00000548278.2
RITA1
RBPJ interacting and tubulin associated 1
chr8_+_96493803 0.24 ENST00000518385.5
ENST00000302190.9
SDC2
syndecan 2
chr1_-_70205531 0.23 ENST00000370952.4
LRRC40
leucine rich repeat containing 40
chr10_+_124801799 0.23 ENST00000298492.6
ABRAXAS2
abraxas 2, BRISC complex subunit
chr18_+_22169580 0.23 ENST00000269216.10
GATA6
GATA binding protein 6
chr17_+_32350132 0.22 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
ZNF207
zinc finger protein 207
chr12_-_121580954 0.22 ENST00000536437.5
ENST00000611216.4
ENST00000538046.6
ENST00000377071.9
KDM2B
lysine demethylase 2B
chr19_+_3094348 0.22 ENST00000078429.9
GNA11
G protein subunit alpha 11
chr2_-_69643703 0.22 ENST00000406297.7
ENST00000409085.9
AAK1
AP2 associated kinase 1
chr3_-_49411917 0.21 ENST00000454011.7
ENST00000445425.6
ENST00000422781.6
ENST00000418115.6
ENST00000678921.2
ENST00000676712.2
RHOA
ras homolog family member A
chr2_+_46617180 0.21 ENST00000238892.4
CRIPT
CXXC repeat containing interactor of PDZ3 domain
chr3_+_5187697 0.21 ENST00000256497.9
EDEM1
ER degradation enhancing alpha-mannosidase like protein 1
chr9_+_126914760 0.19 ENST00000424082.6
ENST00000259351.10
ENST00000394022.7
ENST00000394011.7
ENST00000319107.8
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr7_-_72336995 0.19 ENST00000329008.9
CALN1
calneuron 1
chr2_+_200811882 0.18 ENST00000409600.6
BZW1
basic leucine zipper and W2 domains 1
chr2_+_96816236 0.18 ENST00000377060.7
ENST00000305510.4
CNNM3
cyclin and CBS domain divalent metal cation transport mediator 3
chr1_+_7771263 0.17 ENST00000054666.11
VAMP3
vesicle associated membrane protein 3
chr1_+_201829132 0.17 ENST00000361565.9
IPO9
importin 9
chr22_+_20917398 0.16 ENST00000354336.8
CRKL
CRK like proto-oncogene, adaptor protein
chr6_+_14117764 0.16 ENST00000379153.4
CD83
CD83 molecule
chr9_-_92764795 0.15 ENST00000375512.3
ENST00000356884.11
BICD2
BICD cargo adaptor 2
chr10_-_119872754 0.14 ENST00000360003.7
MCMBP
minichromosome maintenance complex binding protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.0 7.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
1.0 3.9 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.0 1.9 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.9 2.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.9 3.5 GO:0097327 response to antineoplastic agent(GO:0097327)
0.8 4.1 GO:2001076 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.7 2.0 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.6 1.9 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.6 3.1 GO:1901907 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.6 5.3 GO:0016198 axon choice point recognition(GO:0016198)
0.6 1.8 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.6 2.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.5 1.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.5 5.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.5 2.9 GO:0048840 otolith development(GO:0048840)
0.5 2.4 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.5 2.0 GO:0099558 maintenance of synapse structure(GO:0099558)
0.5 2.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.5 1.4 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.5 1.4 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.5 1.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.5 1.4 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.4 2.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.4 4.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4 2.4 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.4 2.8 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.4 2.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.4 4.6 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.3 2.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.3 1.9 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.3 0.9 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.3 0.9 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3 1.7 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.3 3.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.3 0.8 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.3 2.3 GO:0000101 sulfur amino acid transport(GO:0000101)
0.3 1.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.2 5.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 4.6 GO:0006012 galactose metabolic process(GO:0006012)
0.2 0.9 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 3.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 0.4 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.2 1.4 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.2 1.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 5.9 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 0.7 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.2 0.5 GO:0001927 exocyst assembly(GO:0001927)
0.2 1.8 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 0.8 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 0.5 GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176)
0.2 1.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 0.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 0.5 GO:0021764 amygdala development(GO:0021764)
0.1 1.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 2.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 0.4 GO:0036090 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
0.1 0.4 GO:0031627 telomeric loop formation(GO:0031627)
0.1 6.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 5.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.5 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.5 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 4.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 1.8 GO:0042659 regulation of cell fate specification(GO:0042659)
0.1 1.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.1 0.9 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.2 GO:0090154 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.8 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.7 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.8 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 1.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 5.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 2.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 2.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 1.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 3.9 GO:0048286 lung alveolus development(GO:0048286)
0.1 1.3 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.2 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.1 0.2 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 3.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 1.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 2.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.9 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 4.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.4 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 1.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.9 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 1.4 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 0.8 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 5.3 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 4.1 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.4 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 1.4 GO:0008306 associative learning(GO:0008306)
0.0 0.4 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 5.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.4 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.6 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 3.5 GO:0051168 nuclear export(GO:0051168)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.6 2.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.5 2.9 GO:0032584 growth cone membrane(GO:0032584)
0.4 2.6 GO:0070545 PeBoW complex(GO:0070545)
0.3 8.3 GO:0044295 axonal growth cone(GO:0044295)
0.3 1.0 GO:0044393 microspike(GO:0044393)
0.3 1.4 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 3.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 2.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 1.8 GO:0070187 telosome(GO:0070187)
0.2 2.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 3.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 0.8 GO:0033503 HULC complex(GO:0033503)
0.2 1.1 GO:0036021 endolysosome lumen(GO:0036021)
0.2 2.3 GO:0000145 exocyst(GO:0000145)
0.2 1.5 GO:0070852 cell body fiber(GO:0070852)
0.1 0.7 GO:0044308 axonal spine(GO:0044308)
0.1 3.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 3.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 2.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.7 GO:0033270 paranode region of axon(GO:0033270)
0.1 2.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 3.2 GO:0000792 heterochromatin(GO:0000792)
0.1 2.2 GO:0030057 desmosome(GO:0030057)
0.1 1.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.7 GO:0005915 zonula adherens(GO:0005915)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 3.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.3 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.4 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 1.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.4 GO:0043034 costamere(GO:0043034)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 1.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.8 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 4.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 4.9 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 9.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.3 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 1.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 8.9 GO:0005769 early endosome(GO:0005769)
0.0 2.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 5.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 1.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.5 GO:0016605 PML body(GO:0016605)
0.0 2.5 GO:0031252 cell leading edge(GO:0031252)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 7.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
1.0 3.9 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.8 2.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.7 4.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.6 3.1 GO:0052848 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.5 3.3 GO:0034046 poly(G) binding(GO:0034046)
0.5 1.9 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.5 1.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.4 3.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.4 1.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4 1.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 1.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 3.2 GO:0034235 GPI anchor binding(GO:0034235)
0.3 0.9 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3 2.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.3 4.2 GO:0042577 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.3 2.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 2.3 GO:0030274 LIM domain binding(GO:0030274)
0.2 3.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 2.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 0.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 7.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.8 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 3.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.0 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 2.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.5 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 2.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.4 GO:0030552 cAMP binding(GO:0030552)
0.1 2.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 4.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 4.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 3.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 2.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 1.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.5 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.8 GO:0008097 5S rRNA binding(GO:0008097)
0.1 2.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0034452 dynactin binding(GO:0034452)
0.0 1.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 5.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 3.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.1 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 3.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 4.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 2.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 3.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.5 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 5.8 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 5.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 7.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 1.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 4.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.7 PID AURORA B PATHWAY Aurora B signaling
0.0 1.4 PID ATM PATHWAY ATM pathway
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.3 3.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 1.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 1.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 3.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 4.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.8 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 3.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation