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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UGGUCCC

Z-value: 1.82

Motif logo

miRNA associated with seed UGGUCCC

NamemiRBASE accession

Activity profile of UGGUCCC motif

Sorted Z-values of UGGUCCC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UGGUCCC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_+_11890723 16.82 ENST00000254977.7
BTB domain containing 3
chr5_+_141359970 13.45 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr5_+_141370236 13.01 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr5_+_141350081 13.00 ENST00000523390.2
ENST00000611598.1
protocadherin gamma subfamily B, 1
chr5_+_141417659 12.92 ENST00000398594.4
protocadherin gamma subfamily B, 7
chr5_+_141392616 12.62 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr5_+_141382702 12.43 ENST00000617050.1
ENST00000518325.2
protocadherin gamma subfamily A, 7
chr5_+_141484997 12.32 ENST00000617094.1
ENST00000306593.2
ENST00000610539.1
ENST00000618371.4
protocadherin gamma subfamily C, 4
chr4_-_176002332 12.07 ENST00000280187.11
ENST00000512509.5
glycoprotein M6A
chr14_+_90397019 12.00 ENST00000447653.8
ENST00000356978.9
ENST00000626705.2
calmodulin 1
chr5_+_141489066 11.97 ENST00000252087.3
protocadherin gamma subfamily C, 5
chr5_-_134226059 11.80 ENST00000519718.1
ENST00000481195.6
novel protein
protein phosphatase 2 catalytic subunit alpha
chr10_+_17644126 11.17 ENST00000377524.8
signal transducing adaptor molecule
chr12_-_108731505 10.83 ENST00000261401.8
ENST00000552871.5
coronin 1C
chrX_+_40580894 10.60 ENST00000636409.1
ENST00000637327.1
ENST00000637526.1
ENST00000638153.1
ENST00000378438.9
ENST00000636970.1
ENST00000636196.1
ENST00000636251.1
ENST00000637482.1
ENST00000636580.2
ENST00000423649.2
ENST00000636287.1
ATPase H+ transporting accessory protein 2
chr6_-_134318097 9.75 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr5_+_141430499 9.48 ENST00000252085.4
protocadherin gamma subfamily A, 12
chr17_+_59619885 9.29 ENST00000269122.8
ENST00000580081.1
ENST00000579456.5
clathrin heavy chain
chr5_+_141364153 9.20 ENST00000518069.2
protocadherin gamma subfamily A, 5
chr15_-_37098281 8.92 ENST00000559085.5
ENST00000397624.7
Meis homeobox 2
chr6_+_110874775 8.80 ENST00000675380.1
ENST00000368882.8
ENST00000368877.9
ENST00000368885.8
ENST00000672937.2
adenosylmethionine decarboxylase 1
chr1_+_47333774 8.59 ENST00000371873.10
cytidine/uridine monophosphate kinase 1
chr12_+_78864768 7.96 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr8_-_102864155 7.94 ENST00000682725.1
ENST00000337198.10
ENST00000681985.1
ENST00000684566.1
ENST00000683787.1
ENST00000682014.1
ENST00000682969.1
ENST00000684721.1
ENST00000347770.8
antizyme inhibitor 1
chr6_-_52577012 7.93 ENST00000182527.4
translocation associated membrane protein 2
chr22_-_38272996 7.90 ENST00000361906.8
transmembrane protein 184B
chr5_+_141387698 7.86 ENST00000615384.1
ENST00000519479.2
protocadherin gamma subfamily B, 4
chr5_+_178859924 7.74 ENST00000322434.8
zinc finger protein 354B
chrX_+_65667645 7.73 ENST00000360270.7
moesin
chr9_+_36190856 7.71 ENST00000433436.6
ENST00000538225.5
ENST00000540080.5
clathrin light chain A
chr5_+_141355003 7.48 ENST00000571252.3
ENST00000612927.1
protocadherin gamma subfamily A, 4
chrX_-_154546832 6.80 ENST00000433845.1
ENST00000439227.5
ENST00000393562.10
glucose-6-phosphate dehydrogenase
chr5_+_141373878 6.65 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr12_-_76559504 6.40 ENST00000547544.5
ENST00000393249.6
oxysterol binding protein like 8
chr6_+_107490103 6.26 ENST00000317357.10
sine oculis binding protein homolog
chr7_+_121873152 6.22 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
protein tyrosine phosphatase receptor type Z1
chr4_-_107720189 6.18 ENST00000265174.5
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr10_-_96586975 6.03 ENST00000371142.9
transmembrane 9 superfamily member 3
chr6_-_17706852 5.92 ENST00000262077.3
nucleoporin 153
chr6_-_10415043 5.85 ENST00000379613.10
transcription factor AP-2 alpha
chr22_-_40856565 5.84 ENST00000620312.4
ENST00000216218.8
ST13 Hsp70 interacting protein
chr1_-_211830748 5.71 ENST00000366997.9
lysophosphatidylglycerol acyltransferase 1
chr5_+_141338753 5.69 ENST00000528330.2
ENST00000394576.3
protocadherin gamma subfamily A, 2
chr1_-_149927756 5.66 ENST00000271628.9
splicing factor 3b subunit 4
chr19_+_34428353 5.63 ENST00000590048.6
ENST00000246548.9
ubiquitin like modifier activating enzyme 2
chr1_-_159923717 5.38 ENST00000368096.5
transgelin 2
chr3_+_45689338 5.24 ENST00000438671.3
ENST00000389061.10
SAC1 like phosphatidylinositide phosphatase
chr1_-_43367956 5.20 ENST00000372458.8
ELOVL fatty acid elongase 1
chr2_-_173965356 5.16 ENST00000310015.12
Sp3 transcription factor
chr6_-_128520358 5.13 ENST00000368215.7
ENST00000532331.5
ENST00000368213.9
ENST00000368207.7
ENST00000525459.1
ENST00000368226.9
ENST00000368210.7
protein tyrosine phosphatase receptor type K
chr1_-_150974823 5.01 ENST00000361419.9
ENST00000368954.10
ceramide synthase 2
chr3_-_32502783 4.97 ENST00000205636.4
CKLF like MARVEL transmembrane domain containing 6
chr16_-_11782552 4.71 ENST00000396516.6
zinc finger CCCH-type containing 7A
chr2_-_25982471 4.62 ENST00000264712.8
kinesin family member 3C
chr17_+_38870050 4.52 ENST00000318008.11
ENST00000435347.7
LIM and SH3 protein 1
chr1_+_201955496 4.49 ENST00000367287.5
translocase of inner mitochondrial membrane 17A
chr10_-_77926724 4.43 ENST00000372391.7
discs large MAGUK scaffold protein 5
chr8_-_70607654 4.30 ENST00000521425.5
translocation associated membrane protein 1
chr7_+_130070518 4.22 ENST00000335420.10
ENST00000463413.1
kelch domain containing 10
chr15_-_49046427 4.22 ENST00000261847.7
ENST00000559471.6
ENST00000380927.6
ENST00000559424.1
SECIS binding protein 2 like
chr19_+_47713412 4.15 ENST00000538399.1
ENST00000263277.8
EH domain containing 2
chr1_-_149917826 4.11 ENST00000369145.1
ENST00000369146.8
synaptic vesicle glycoprotein 2A
chr10_-_125160499 4.07 ENST00000494626.6
ENST00000337195.9
C-terminal binding protein 2
chr8_-_30812773 4.03 ENST00000221138.9
protein phosphatase 2 catalytic subunit beta
chr3_-_48685835 4.01 ENST00000439518.5
ENST00000416649.6
ENST00000294129.7
NCK interacting protein with SH3 domain
chr1_+_15409858 3.98 ENST00000375980.9
EF-hand domain family member D2
chr17_+_74987581 3.96 ENST00000337231.5
cerebellar degeneration related protein 2 like
chr6_+_148342759 3.93 ENST00000367467.8
SAM and SH3 domain containing 1
chr3_+_43286512 3.92 ENST00000454177.5
ENST00000429705.6
ENST00000296088.12
ENST00000437827.1
SNF related kinase
chr1_-_51519236 3.92 ENST00000371730.6
ENST00000371733.8
epidermal growth factor receptor pathway substrate 15
chr1_+_32179665 3.83 ENST00000373610.8
taxilin alpha
chr7_+_157336961 3.81 ENST00000429029.6
DnaJ heat shock protein family (Hsp40) member B6
chr14_+_23306816 3.78 ENST00000678311.1
ENST00000557579.2
ENST00000250405.10
ENST00000679000.1
ENST00000557236.6
ENST00000678502.1
ENST00000553781.5
BCL2 like 2
BCL2L2-PABPN1 readthrough
chr20_-_59042748 3.69 ENST00000355937.9
ENST00000371033.9
PRELI domain containing 3B
chrX_-_109733249 3.63 ENST00000469796.7
ENST00000672401.1
ENST00000671846.1
acyl-CoA synthetase long chain family member 4
chr6_-_81752671 3.55 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr15_+_80779343 3.53 ENST00000220244.7
ENST00000394685.8
ENST00000356249.9
cell migration inducing hyaluronidase 1
chr8_-_133297092 3.46 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr16_-_15643105 3.40 ENST00000548025.5
ENST00000551742.5
ENST00000396368.8
meiosis regulator and mRNA stability factor 1
chr2_-_64653906 3.35 ENST00000313349.3
SERTA domain containing 2
chr1_-_154558650 3.27 ENST00000292211.5
ubiquitin conjugating enzyme E2 Q1
chr22_-_27919199 3.24 ENST00000634017.1
ENST00000436663.1
ENST00000320996.14
ENST00000335272.10
ENST00000455418.7
phosphatidylinositol transfer protein beta
chr7_+_55365317 3.17 ENST00000254770.3
LanC like 2
chr21_-_14383125 3.13 ENST00000285667.4
heat shock protein family A (Hsp70) member 13
chr8_-_52714414 3.03 ENST00000435644.6
ENST00000518710.5
ENST00000025008.10
ENST00000517963.1
RB1 inducible coiled-coil 1
chr3_+_10992717 3.03 ENST00000642767.1
ENST00000425938.6
ENST00000642515.1
ENST00000643498.1
ENST00000646072.1
ENST00000646570.1
ENST00000287766.10
ENST00000645281.1
ENST00000642820.1
ENST00000645054.1
ENST00000642735.1
ENST00000646022.1
ENST00000645776.1
ENST00000645592.1
ENST00000646924.1
ENST00000645974.1
ENST00000644314.1
ENST00000642639.1
ENST00000646060.1
ENST00000642201.1
ENST00000646487.1
ENST00000647194.1
ENST00000646088.1
solute carrier family 6 member 1
chrX_-_49043345 2.96 ENST00000315869.8
transcription factor binding to IGHM enhancer 3
chrX_-_136880715 2.89 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr6_-_89412219 2.86 ENST00000369415.9
Ras related GTP binding D
chr14_-_74713041 2.83 ENST00000356357.9
ENST00000555249.1
ENST00000681599.1
ENST00000556202.5
ENST00000681099.1
apoptosis resistant E3 ubiquitin protein ligase 1
chr17_+_40140500 2.80 ENST00000264645.12
CASC3 exon junction complex subunit
chr13_-_77327050 2.76 ENST00000684354.1
ENST00000682321.1
ENST00000683823.1
ENST00000683697.1
ENST00000357337.11
ENST00000544440.7
MYC binding protein 2
chr1_+_109548567 2.74 ENST00000369851.7
G protein subunit alpha i3
chr14_+_74881887 2.74 ENST00000334220.9
ENST00000626051.1
ENST00000554806.5
dihydrolipoamide S-succinyltransferase
chr11_+_57753243 2.73 ENST00000524630.5
ENST00000529919.5
ENST00000533189.1
catenin delta 1
chr14_-_63728027 2.70 ENST00000247225.7
sphingosine-1-phosphate phosphatase 1
chr1_+_218285283 2.68 ENST00000366932.4
ribosomal RNA processing 15 homolog
chr22_-_38844020 2.66 ENST00000333039.4
neuronal pentraxin receptor
chr17_-_43022350 2.65 ENST00000587173.5
ENST00000355653.8
vesicle amine transport 1
chr10_+_84139491 2.62 ENST00000372134.6
growth hormone inducible transmembrane protein
chr6_+_39792993 2.52 ENST00000538976.5
dishevelled associated activator of morphogenesis 2
chr9_-_35072588 2.52 ENST00000677257.1
ENST00000679862.1
ENST00000679902.1
ENST00000358901.11
ENST00000681335.1
ENST00000681386.1
ENST00000679647.1
ENST00000448530.6
valosin containing protein
chrX_+_41334154 2.47 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DEAD-box helicase 3 X-linked
chr14_-_25049889 2.47 ENST00000419632.6
ENST00000396700.5
syntaxin binding protein 6
chr9_-_121201836 2.45 ENST00000373840.9
RAB14, member RAS oncogene family
chr5_+_179732811 2.44 ENST00000292599.4
mastermind like transcriptional coactivator 1
chr5_-_16508990 2.42 ENST00000399793.6
reticulophagy regulator 1
chr11_+_112025367 2.41 ENST00000679614.1
ENST00000679878.1
ENST00000280346.11
ENST00000681339.1
ENST00000681328.1
ENST00000681316.1
ENST00000531306.2
ENST00000680331.1
ENST00000393051.5
dihydrolipoamide S-acetyltransferase
chr17_-_1456149 2.40 ENST00000574295.1
ENST00000398970.5
ENST00000300574.3
CRK proto-oncogene, adaptor protein
chr15_+_22838635 2.38 ENST00000398014.7
ENST00000359727.8
ENST00000674173.1
ENST00000337451.8
ENST00000674289.1
ENST00000674477.1
ENST00000398013.7
ENST00000674330.1
ENST00000560039.1
ENST00000539711.2
NIPA magnesium transporter 2
chr5_+_141343818 2.25 ENST00000619750.1
ENST00000253812.8
protocadherin gamma subfamily A, 3
chr5_+_151771884 2.16 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr16_+_4958289 2.15 ENST00000251170.12
SEC14 like lipid binding 5
chr19_+_17511606 2.13 ENST00000252603.7
ENST00000600923.5
6-phosphogluconolactonase
chr5_+_141475928 2.08 ENST00000611950.1
ENST00000308177.5
ENST00000617641.4
ENST00000621008.1
ENST00000617222.4
protocadherin gamma subfamily C, 3
chr1_-_39691393 2.08 ENST00000372844.8
hippocalcin like 4
chr1_-_88992732 1.96 ENST00000413769.1
ENST00000321792.5
ENST00000370491.7
RBMX like 1
kynurenine aminotransferase 3
chr19_-_14518383 1.95 ENST00000254322.3
ENST00000595139.2
DnaJ heat shock protein family (Hsp40) member B1
chr14_-_21383989 1.90 ENST00000216297.7
SPT16 homolog, facilitates chromatin remodeling subunit
chr2_+_108719473 1.88 ENST00000283195.11
RAN binding protein 2
chr3_-_49786508 1.87 ENST00000395238.5
ENST00000468463.5
ENST00000321599.9
ENST00000460540.1
inositol hexakisphosphate kinase 1
chr17_-_81871314 1.79 ENST00000581876.5
ENST00000584461.5
ENST00000269321.12
ENST00000583868.5
ENST00000400721.8
Rho GDP dissociation inhibitor alpha
chr16_-_10580577 1.77 ENST00000359543.8
epithelial membrane protein 2
chr5_+_141412979 1.77 ENST00000612503.1
ENST00000398610.3
protocadherin gamma subfamily A, 10
chr9_-_71768386 1.76 ENST00000377066.9
ENST00000377044.9
cell migration inducing hyaluronidase 2
chrX_-_132218124 1.70 ENST00000342983.6
RAP2C, member of RAS oncogene family
chr17_-_8163522 1.69 ENST00000404970.3
vesicle associated membrane protein 2
chr4_-_88823306 1.68 ENST00000395002.6
family with sequence similarity 13 member A
chr9_-_121370235 1.62 ENST00000286713.7
ENST00000347359.3
stomatin
chr6_+_42984532 1.54 ENST00000394110.7
ENST00000472118.5
ENST00000485511.6
ENST00000461010.5
protein phosphatase 2 regulatory subunit B'delta
chr12_-_51083582 1.52 ENST00000548206.1
ENST00000546935.5
ENST00000228515.6
ENST00000548981.5
cysteine and serine rich nuclear protein 2
chr22_-_36387949 1.48 ENST00000216181.11
myosin heavy chain 9
chr11_-_9003994 1.34 ENST00000309166.8
ENST00000525100.1
ENST00000531090.5
nuclear receptor interacting protein 3
chr3_-_15859771 1.34 ENST00000399451.6
ankyrin repeat domain 28
chr16_-_2340703 1.34 ENST00000301732.10
ENST00000382381.7
ATP binding cassette subfamily A member 3
chr1_+_86914616 1.28 ENST00000370550.10
ENST00000370551.8
heparan sulfate 2-O-sulfotransferase 1
chr19_-_4400418 1.25 ENST00000598564.5
ENST00000417295.6
ENST00000269886.7
SH3 domain containing GRB2 like 1, endophilin A2
chr4_-_7871986 1.25 ENST00000360265.9
actin filament associated protein 1
chr5_+_141330494 1.23 ENST00000517417.3
ENST00000378105.4
protocadherin gamma subfamily A, 1
chr12_-_81759307 1.21 ENST00000547623.5
ENST00000549396.6
PTPRF interacting protein alpha 2
chr19_-_47471886 1.18 ENST00000236877.11
ENST00000597014.1
solute carrier family 8 member A2
chrX_-_124963768 1.15 ENST00000371130.7
ENST00000422452.2
teneurin transmembrane protein 1
chr17_-_76737321 1.13 ENST00000359995.10
ENST00000508921.7
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
serine and arginine rich splicing factor 2
chr10_-_5813387 1.13 ENST00000456041.5
ENST00000380181.7
ENST00000418688.5
ENST00000609712.1
ENST00000380191.9
GDP dissociation inhibitor 2
chr2_-_231781268 1.13 ENST00000287600.9
ENST00000409772.5
phosphodiesterase 6D
chr5_+_66144288 1.10 ENST00000334121.11
splicing regulatory glutamic acid and lysine rich protein 1
chr5_+_141402764 1.10 ENST00000573521.2
ENST00000616887.1
protocadherin gamma subfamily A, 9
chr5_+_141408032 1.08 ENST00000520790.1
protocadherin gamma subfamily B, 6
chr14_-_22919124 1.06 ENST00000555209.5
ENST00000554256.5
ENST00000557403.5
ENST00000359890.8
ENST00000557549.5
ENST00000555676.5
ENST00000557571.5
ENST00000557464.5
ENST00000554618.5
ENST00000556862.5
ENST00000555722.5
ENST00000346528.9
ENST00000542016.6
ENST00000399922.6
ENST00000557227.5
RNA binding motif protein 23
chr2_+_27370496 1.02 ENST00000537606.5
ENST00000233575.7
sorting nexin 17
chr11_-_75351609 1.02 ENST00000420843.7
arrestin beta 1
chr20_+_58389197 1.01 ENST00000475243.6
ENST00000395802.7
VAMP associated protein B and C
chr7_+_91940851 1.00 ENST00000679821.1
ENST00000681722.1
ENST00000680181.1
ENST00000356239.8
ENST00000679521.1
ENST00000680952.1
ENST00000681412.1
ENST00000680766.1
A-kinase anchoring protein 9
chr17_+_28662183 0.92 ENST00000347486.8
ENST00000314616.11
SPT6 homolog, histone chaperone and transcription elongation factor
chr9_+_125261788 0.92 ENST00000461379.5
ENST00000297933.11
ENST00000394084.5
ENST00000394105.6
ENST00000470056.5
ENST00000394083.6
ENST00000495955.5
ENST00000467750.5
GTPase activating protein and VPS9 domains 1
chr11_-_62646598 0.90 ENST00000648273.1
ENST00000356638.8
ENST00000346178.8
ENST00000534779.5
ENST00000525994.1
ENST00000540933.5
glucosidase II alpha subunit
chr11_-_6481304 0.85 ENST00000254584.6
ENST00000525235.1
ENST00000396777.8
ENST00000445086.6
ADP ribosylation factor interacting protein 2
chr19_+_15107369 0.85 ENST00000342784.7
ENST00000597977.5
ENST00000600440.5
synapse defective Rho GTPase homolog 1
chr6_+_163414637 0.84 ENST00000453779.6
ENST00000275262.11
ENST00000392127.6
QKI, KH domain containing RNA binding
chr1_-_107965009 0.83 ENST00000527011.5
ENST00000370056.9
vav guanine nucleotide exchange factor 3
chr11_+_61752603 0.82 ENST00000278836.10
myelin regulatory factor
chr2_-_16665816 0.78 ENST00000406434.5
ENST00000381323.7
CYFIP related Rac1 interactor A
chr12_+_67269328 0.77 ENST00000545606.6
cullin associated and neddylation dissociated 1
chr11_-_117316230 0.77 ENST00000313005.11
ENST00000528053.5
beta-secretase 1
chr12_-_132828823 0.76 ENST00000545875.4
ENST00000456883.6
ENST00000450791.7
ENST00000204726.8
golgin A3
chr12_+_10212867 0.76 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr17_-_42121330 0.74 ENST00000225916.10
lysine acetyltransferase 2A
chr1_+_22052627 0.73 ENST00000400259.5
ENST00000344548.7
ENST00000315554.13
ENST00000656825.1
ENST00000651171.1
ENST00000652582.1
ENST00000667384.1
cell division cycle 42
chr1_+_32651164 0.72 ENST00000373493.10
ENST00000373485.5
ENST00000458695.6
RB binding protein 4, chromatin remodeling factor
chr14_+_88562952 0.69 ENST00000302216.12
ENST00000554602.5
ENST00000556945.5
ENST00000556158.5
ENST00000557607.5
ENST00000555799.5
ENST00000251038.10
ENST00000555755.5
zinc finger CCCH-type containing 14
chr12_-_48788995 0.66 ENST00000550422.5
ENST00000357869.8
adenylate cyclase 6
chr19_+_48965304 0.66 ENST00000331825.11
ferritin light chain
chr17_+_7884783 0.63 ENST00000380358.9
chromodomain helicase DNA binding protein 3
chr9_-_21335340 0.62 ENST00000359039.5
kelch like family member 9
chr1_+_43979179 0.59 ENST00000434555.7
ENST00000372324.6
ENST00000481924.2
beta-1,4-galactosyltransferase 2
chr15_+_51829644 0.58 ENST00000308580.12
tropomodulin 3
chrX_-_71254106 0.57 ENST00000373984.7
ENST00000314425.9
ENST00000373982.5
zinc finger MYM-type containing 3
chr9_-_10612966 0.57 ENST00000381196.9
protein tyrosine phosphatase receptor type D
chr19_+_16111868 0.53 ENST00000300935.8
ENST00000586682.1
RAB8A, member RAS oncogene family
chr6_+_133953210 0.51 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr10_-_100185993 0.45 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ER lipid raft associated 1
chr2_+_46698909 0.44 ENST00000650611.1
ENST00000306503.5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr12_-_105236074 0.43 ENST00000551662.5
ENST00000553097.5
ENST00000258530.8
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr6_+_33200820 0.42 ENST00000374675.7
solute carrier family 39 member 7
chr5_-_90409720 0.40 ENST00000522864.5
ENST00000283122.8
ENST00000522083.5
ENST00000522565.5
ENST00000522842.1
centrin 3
chr16_-_67483541 0.39 ENST00000290953.3
agouti related neuropeptide
chr6_+_21593742 0.36 ENST00000244745.4
SRY-box transcription factor 4
chr9_-_2844058 0.35 ENST00000397885.3
pumilio RNA binding family member 3
chr1_+_212858267 0.33 ENST00000366971.9
FLVCR heme transporter 1
chr9_+_128787243 0.29 ENST00000372648.10
TBC1 domain family member 13
chr17_+_42682470 0.28 ENST00000264638.9
contactin associated protein 1
chr20_+_37694022 0.25 ENST00000361383.11
ENST00000447935.3
ENST00000628103.2
catenin beta like 1
chr19_-_10010492 0.19 ENST00000264828.4
collagen type V alpha 3 chain
chr2_-_64019072 0.19 ENST00000409558.8
VPS54 subunit of GARP complex
chr7_+_5190196 0.14 ENST00000401525.7
ENST00000288828.9
ENST00000404704.7
WD repeat domain, phosphoinositide interacting 2
chrX_+_96684801 0.14 ENST00000324765.13
diaphanous related formin 2
chr6_-_35921079 0.10 ENST00000507909.1
ENST00000373825.7
SRSF protein kinase 1
chr10_-_126388455 0.08 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM metallopeptidase domain 12
chr9_+_116153783 0.06 ENST00000328252.4
pappalysin 1
chr16_+_12901591 0.06 ENST00000558583.3
shisa family member 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
2.6 7.9 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
2.3 9.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
2.2 8.9 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
2.1 6.2 GO:0000103 sulfate assimilation(GO:0000103)
2.0 7.9 GO:0045048 protein insertion into ER membrane(GO:0045048)
2.0 5.9 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
1.5 5.9 GO:0003409 optic cup structural organization(GO:0003409)
1.4 11.2 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
1.4 9.7 GO:0070294 renal sodium ion absorption(GO:0070294)
1.3 3.9 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.3 7.7 GO:0022614 membrane to membrane docking(GO:0022614)
1.3 8.8 GO:0008295 spermine metabolic process(GO:0008215) spermidine biosynthetic process(GO:0008295)
1.3 5.0 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) negative regulation of glial cell migration(GO:1903976)
1.2 5.8 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
1.1 8.6 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
1.1 3.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
1.0 3.0 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
1.0 10.6 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.9 6.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.9 2.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.9 8.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.9 150.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.8 2.5 GO:1903006 flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.8 10.8 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.8 2.4 GO:0003162 atrioventricular node development(GO:0003162)
0.7 4.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.7 2.9 GO:0071233 cellular response to leucine(GO:0071233)
0.7 11.8 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.7 5.5 GO:0061709 reticulophagy(GO:0061709)
0.7 3.9 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.7 5.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 3.5 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.5 3.3 GO:0070459 prolactin secretion(GO:0070459)
0.5 3.8 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.5 2.7 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.5 4.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.5 1.5 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.5 3.8 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.5 4.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.4 4.8 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.4 2.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.4 4.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 1.8 GO:0070836 caveola assembly(GO:0070836)
0.4 4.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 2.6 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.3 2.0 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.3 5.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 5.7 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.3 3.5 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.3 1.9 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.3 7.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.3 4.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 1.6 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.3 2.4 GO:0001878 response to yeast(GO:0001878)
0.3 2.4 GO:0015693 magnesium ion transport(GO:0015693)
0.3 2.8 GO:0008298 intracellular mRNA localization(GO:0008298)
0.2 2.5 GO:0051601 exocyst localization(GO:0051601)
0.2 0.7 GO:0071338 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.2 9.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 0.9 GO:0061086 regulation of mRNA export from nucleus(GO:0010793) negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 0.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.2 0.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 3.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 1.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 0.7 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.2 1.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 5.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 2.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.4 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 8.6 GO:0008542 visual learning(GO:0008542)
0.1 2.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.0 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 3.4 GO:0007143 female meiotic division(GO:0007143)
0.1 1.9 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 1.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 4.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.7 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 5.4 GO:0090102 cochlea development(GO:0090102)
0.1 0.5 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 6.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 2.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.8 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.5 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 17.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 2.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 2.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 4.0 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 0.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 1.8 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 1.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:1903540 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 4.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 4.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 2.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 5.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.8 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 1.2 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:1901992 positive regulation of mitotic cell cycle phase transition(GO:1901992)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.2 GO:0033565 ESCRT-0 complex(GO:0033565)
1.7 17.0 GO:0071439 clathrin complex(GO:0071439)
1.6 8.0 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.4 5.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.2 6.2 GO:0072534 perineuronal net(GO:0072534)
0.6 2.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.6 1.9 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.6 9.5 GO:0016600 flotillin complex(GO:0016600)
0.5 9.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5 12.1 GO:0044295 axonal growth cone(GO:0044295)
0.5 2.9 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 17.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 1.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.4 2.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.4 2.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.4 2.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.4 5.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 4.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 4.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 2.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 0.8 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.3 4.1 GO:0097470 ribbon synapse(GO:0097470)
0.2 1.0 GO:0044307 dendritic branch(GO:0044307)
0.2 5.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 2.7 GO:0005915 zonula adherens(GO:0005915)
0.2 3.6 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 1.1 GO:0035061 interchromatin granule(GO:0035061)
0.2 1.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 2.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.2 3.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 0.7 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 2.7 GO:0042588 zymogen granule(GO:0042588)
0.2 3.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 12.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 7.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 4.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.5 GO:0017119 Golgi transport complex(GO:0017119)
0.1 12.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 4.0 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 5.0 GO:0035579 azurophil granule membrane(GO:0035577) specific granule membrane(GO:0035579)
0.1 2.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 4.6 GO:0005871 kinesin complex(GO:0005871)
0.1 7.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 11.4 GO:0000922 spindle pole(GO:0000922)
0.1 5.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 112.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.7 GO:0030914 STAGA complex(GO:0030914)
0.0 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 14.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 3.3 GO:0030175 filopodium(GO:0030175)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 3.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 5.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 5.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 16.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 9.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.5 GO:0005769 early endosome(GO:0005769)
0.0 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0009041 uridylate kinase activity(GO:0009041)
2.3 6.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.6 8.0 GO:0030348 syntaxin-3 binding(GO:0030348)
1.2 3.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.2 5.8 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
1.1 7.9 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.1 2.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.9 3.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.8 9.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.8 11.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.7 5.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.7 5.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.7 2.0 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
0.7 5.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.6 5.7 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.6 1.9 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.6 2.5 GO:0043273 CTPase activity(GO:0043273)
0.6 4.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.6 2.4 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.6 12.6 GO:0050811 GABA receptor binding(GO:0050811)
0.6 4.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.6 5.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.6 4.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.5 10.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5 2.7 GO:0016748 succinyltransferase activity(GO:0016748)
0.4 2.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.4 2.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 3.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4 11.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 9.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.4 7.4 GO:0043495 protein anchor(GO:0043495)
0.3 1.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 4.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 1.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.6 GO:0004461 lactose synthase activity(GO:0004461)
0.2 0.8 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 6.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.2 177.2 GO:0005509 calcium ion binding(GO:0005509)
0.2 19.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 2.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 5.8 GO:0001671 ATPase activator activity(GO:0001671)
0.2 8.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 10.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 2.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.2 GO:0015368 calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.1 2.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 2.3 GO:0051400 BH domain binding(GO:0051400)
0.1 3.0 GO:0031489 myosin V binding(GO:0031489)
0.1 0.9 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 4.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.7 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 1.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.9 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 3.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 9.8 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 3.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 4.6 GO:0019003 GDP binding(GO:0019003)
0.1 9.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 6.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 2.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 2.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 4.6 GO:0003777 microtubule motor activity(GO:0003777)
0.1 4.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.7 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 4.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 2.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 8.8 GO:0005125 cytokine activity(GO:0005125)
0.0 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 7.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.8 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0005319 lipid transporter activity(GO:0005319)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.6 PID ARF 3PATHWAY Arf1 pathway
0.3 9.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 12.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 10.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 12.1 PID INSULIN PATHWAY Insulin Pathway
0.2 12.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 5.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 12.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 5.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 5.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.3 PID E2F PATHWAY E2F transcription factor network
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 15.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.8 17.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.6 12.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.5 15.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.4 9.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 8.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 5.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 8.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 8.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 7.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.3 6.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 8.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 5.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 7.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.2 4.6 REACTOME KINESINS Genes involved in Kinesins
0.2 3.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 3.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 2.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 1.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 6.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 7.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.2 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.1 3.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 6.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 4.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 2.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 3.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.7 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates