Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for UUGGCAC
Z-value: 7.65
Motif logo
miRNA associated with seed UUGGCAC
| Name | miRBASE accession |
|---|---|
|
hsa-miR-1271-5p
|
MIMAT0005796 |
|
hsa-miR-96-5p
|
MIMAT0000095 |
Activity profile of UUGGCAC motif
Sorted Z-values of UUGGCAC motif
Network of associatons between targets according to the STRING database.
First level regulatory network of UUGGCAC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.5 | 19.5 | GO:0006210 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 4.5 | 13.4 | GO:1905053 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 3.8 | 15.4 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 3.6 | 10.9 | GO:0021718 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 3.6 | 10.8 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 3.4 | 16.8 | GO:2001076 | regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076) |
| 3.3 | 16.6 | GO:0072716 | response to sorbitol(GO:0072708) response to actinomycin D(GO:0072716) |
| 3.3 | 16.6 | GO:0045906 | negative regulation of vasoconstriction(GO:0045906) |
| 2.9 | 11.5 | GO:0097676 | histone H3-K36 dimethylation(GO:0097676) |
| 2.9 | 11.4 | GO:0099558 | maintenance of synapse structure(GO:0099558) |
| 2.8 | 33.2 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 2.8 | 16.5 | GO:0021523 | somatic motor neuron differentiation(GO:0021523) |
| 2.6 | 15.4 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 2.6 | 12.8 | GO:1901906 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 2.4 | 21.5 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 2.3 | 13.8 | GO:0071500 | cellular response to nitrosative stress(GO:0071500) |
| 2.3 | 6.9 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 2.2 | 8.9 | GO:1902530 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 2.2 | 4.4 | GO:0048669 | collateral sprouting in absence of injury(GO:0048669) |
| 2.2 | 2.2 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
| 2.2 | 19.5 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 2.0 | 14.2 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 1.8 | 9.0 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 1.8 | 5.3 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
| 1.7 | 10.4 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 1.7 | 15.1 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 1.6 | 6.5 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 1.6 | 14.6 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 1.6 | 14.4 | GO:0000101 | sulfur amino acid transport(GO:0000101) |
| 1.6 | 9.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 1.6 | 15.9 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 1.6 | 1.6 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
| 1.5 | 6.2 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
| 1.5 | 9.2 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 1.5 | 6.0 | GO:0014053 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450) |
| 1.5 | 4.5 | GO:1901993 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 1.5 | 7.3 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 1.5 | 11.7 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 1.4 | 15.5 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 1.4 | 16.7 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 1.4 | 4.1 | GO:0021636 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
| 1.4 | 12.2 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 1.3 | 4.0 | GO:0070079 | peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079) |
| 1.3 | 4.0 | GO:0061091 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 1.3 | 5.2 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) |
| 1.3 | 9.0 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 1.3 | 3.8 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) |
| 1.3 | 12.7 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 1.3 | 5.0 | GO:0036515 | serotonergic neuron axon guidance(GO:0036515) |
| 1.3 | 8.8 | GO:0021999 | neural plate anterior/posterior regionalization(GO:0021999) |
| 1.2 | 5.0 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 1.2 | 3.7 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 1.2 | 3.7 | GO:1900275 | negative regulation of phospholipase C activity(GO:1900275) |
| 1.2 | 6.1 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 1.2 | 7.3 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 1.2 | 3.6 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 1.2 | 3.6 | GO:0048840 | otolith development(GO:0048840) |
| 1.2 | 3.5 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
| 1.2 | 1.2 | GO:0003180 | aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180) |
| 1.2 | 5.8 | GO:0021764 | amygdala development(GO:0021764) |
| 1.1 | 4.5 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 1.1 | 3.3 | GO:0072276 | metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
| 1.1 | 7.7 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 1.1 | 18.4 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 1.1 | 6.4 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 1.1 | 13.8 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 1.1 | 6.3 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 1.0 | 4.1 | GO:0036269 | swimming behavior(GO:0036269) |
| 1.0 | 7.2 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 1.0 | 9.2 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 1.0 | 3.9 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 1.0 | 2.9 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 1.0 | 17.3 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 1.0 | 2.9 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 1.0 | 3.8 | GO:1904379 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 1.0 | 5.7 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.9 | 7.6 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.9 | 7.5 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.9 | 5.6 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.9 | 2.8 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.9 | 1.8 | GO:0035625 | epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.9 | 3.6 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.9 | 3.5 | GO:1902617 | response to fluoride(GO:1902617) |
| 0.9 | 1.7 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.8 | 5.0 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.8 | 4.2 | GO:0061364 | apoptotic process involved in luteolysis(GO:0061364) |
| 0.8 | 4.9 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.8 | 12.2 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.8 | 4.9 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.8 | 9.5 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.8 | 12.4 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.8 | 32.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.7 | 17.1 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.7 | 33.4 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.7 | 7.9 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.7 | 14.3 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.7 | 12.7 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.7 | 20.4 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.7 | 2.6 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.6 | 2.6 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.6 | 10.4 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.6 | 8.3 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
| 0.6 | 4.5 | GO:0001842 | neural fold formation(GO:0001842) |
| 0.6 | 15.9 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.6 | 1.9 | GO:0001554 | luteolysis(GO:0001554) |
| 0.6 | 6.9 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.6 | 16.2 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.6 | 6.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.6 | 7.5 | GO:0045955 | negative regulation of calcium ion-dependent exocytosis(GO:0045955) |
| 0.6 | 3.6 | GO:0030860 | regulation of polarized epithelial cell differentiation(GO:0030860) |
| 0.6 | 1.8 | GO:0001927 | exocyst assembly(GO:0001927) |
| 0.6 | 4.6 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.6 | 17.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.6 | 5.6 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.6 | 2.8 | GO:2000317 | negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
| 0.5 | 4.4 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.5 | 7.1 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.5 | 3.8 | GO:0090210 | regulation of establishment of blood-brain barrier(GO:0090210) |
| 0.5 | 3.8 | GO:0048842 | positive regulation of axon extension involved in axon guidance(GO:0048842) |
| 0.5 | 11.2 | GO:0046051 | UTP metabolic process(GO:0046051) |
| 0.5 | 7.7 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.5 | 6.5 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.5 | 8.4 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.5 | 12.9 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.5 | 3.8 | GO:0070236 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.5 | 12.6 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.5 | 3.3 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.5 | 1.4 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) fasciculation of motor neuron axon(GO:0097156) |
| 0.4 | 23.2 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.4 | 4.9 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.4 | 4.0 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.4 | 6.5 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.4 | 3.0 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.4 | 1.3 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
| 0.4 | 1.3 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 0.4 | 10.7 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.4 | 1.6 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.4 | 9.5 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.4 | 3.9 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.4 | 4.2 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.4 | 1.5 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.4 | 9.5 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.4 | 3.8 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.4 | 6.1 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.3 | 5.6 | GO:0021794 | thalamus development(GO:0021794) |
| 0.3 | 7.7 | GO:1900151 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.3 | 3.5 | GO:0097012 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
| 0.3 | 4.4 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.3 | 2.7 | GO:0061709 | reticulophagy(GO:0061709) |
| 0.3 | 1.6 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 0.3 | 4.1 | GO:0019317 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.3 | 25.1 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.3 | 7.8 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.3 | 9.1 | GO:0022011 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.3 | 2.1 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.3 | 5.3 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.3 | 0.9 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.3 | 6.2 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.3 | 16.1 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.3 | 2.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.3 | 4.8 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.3 | 6.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.2 | 8.0 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.2 | 15.3 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.2 | 1.6 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) |
| 0.2 | 3.3 | GO:1901621 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.2 | 7.9 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.2 | 11.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.2 | 6.0 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.2 | 3.4 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.2 | 15.2 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.2 | 0.8 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 0.2 | 9.6 | GO:0008306 | associative learning(GO:0008306) |
| 0.2 | 4.9 | GO:0039694 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.2 | 2.5 | GO:0035404 | histone-serine phosphorylation(GO:0035404) |
| 0.2 | 5.9 | GO:0046928 | regulation of neurotransmitter secretion(GO:0046928) |
| 0.2 | 3.1 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.2 | 0.5 | GO:0097272 | ammonia homeostasis(GO:0097272) |
| 0.2 | 4.5 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.2 | 1.3 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.2 | 2.0 | GO:1990118 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 4.4 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 5.3 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 0.1 | 6.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 16.1 | GO:0006836 | neurotransmitter transport(GO:0006836) |
| 0.1 | 1.5 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.1 | 1.5 | GO:1900103 | positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103) |
| 0.1 | 16.6 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.1 | 0.4 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
| 0.1 | 1.2 | GO:0051791 | medium-chain fatty acid metabolic process(GO:0051791) |
| 0.1 | 0.7 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.1 | 2.5 | GO:0003416 | endochondral bone growth(GO:0003416) |
| 0.1 | 1.4 | GO:0007616 | long-term memory(GO:0007616) |
| 0.1 | 0.3 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.1 | 2.1 | GO:0097503 | sialylation(GO:0097503) |
| 0.1 | 0.3 | GO:0003064 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.1 | 8.0 | GO:0050806 | positive regulation of synaptic transmission(GO:0050806) |
| 0.1 | 0.8 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 2.1 | GO:0006098 | pentose-phosphate shunt(GO:0006098) |
| 0.1 | 1.8 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 5.5 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 3.3 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.1 | 1.2 | GO:0050951 | sensory perception of temperature stimulus(GO:0050951) |
| 0.1 | 20.9 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 1.4 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 1.4 | GO:0032354 | response to follicle-stimulating hormone(GO:0032354) |
| 0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.9 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.1 | 1.8 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.1 | 1.2 | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) |
| 0.1 | 3.4 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.1 | 8.4 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.1 | 10.8 | GO:0007601 | visual perception(GO:0007601) |
| 0.1 | 5.0 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.0 | 1.8 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 1.0 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.0 | 1.9 | GO:0042992 | negative regulation of transcription factor import into nucleus(GO:0042992) |
| 0.0 | 1.9 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 1.4 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
| 0.0 | 1.6 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
| 0.0 | 1.2 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.0 | 2.6 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 1.0 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.0 | 0.6 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.3 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
| 0.0 | 2.9 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
| 0.0 | 1.2 | GO:0033173 | calcineurin-NFAT signaling cascade(GO:0033173) |
| 0.0 | 3.3 | GO:0051262 | protein tetramerization(GO:0051262) |
| 0.0 | 0.4 | GO:0045577 | regulation of B cell differentiation(GO:0045577) |
| 0.0 | 0.5 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 0.5 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.0 | 2.0 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.0 | 3.5 | GO:0051260 | protein homooligomerization(GO:0051260) |
| 0.0 | 3.8 | GO:0007268 | chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.6 | 13.8 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 3.9 | 15.4 | GO:0070695 | FHF complex(GO:0070695) |
| 3.8 | 22.7 | GO:0032584 | growth cone membrane(GO:0032584) |
| 3.4 | 17.1 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 3.4 | 17.1 | GO:0044308 | axonal spine(GO:0044308) |
| 2.8 | 16.8 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 2.4 | 7.2 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 2.4 | 9.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 2.2 | 11.2 | GO:0070847 | core mediator complex(GO:0070847) |
| 2.2 | 9.0 | GO:0035363 | histone locus body(GO:0035363) |
| 2.2 | 10.9 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 2.1 | 8.6 | GO:0070876 | SOSS complex(GO:0070876) |
| 2.0 | 6.1 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 1.8 | 43.1 | GO:0044295 | axonal growth cone(GO:0044295) |
| 1.5 | 6.0 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 1.3 | 13.1 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 1.1 | 7.9 | GO:0036157 | outer dynein arm(GO:0036157) |
| 1.1 | 21.1 | GO:0033270 | paranode region of axon(GO:0033270) |
| 1.0 | 4.0 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.9 | 5.3 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.9 | 1.8 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.8 | 9.0 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.8 | 11.4 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.7 | 5.2 | GO:1990745 | EARP complex(GO:1990745) |
| 0.7 | 6.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.7 | 3.5 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.7 | 4.0 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.6 | 10.3 | GO:0005883 | neurofilament(GO:0005883) |
| 0.6 | 3.8 | GO:0044214 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.6 | 34.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.6 | 4.1 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.5 | 5.9 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.5 | 1.6 | GO:0000805 | X chromosome(GO:0000805) |
| 0.5 | 6.9 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.5 | 5.0 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.5 | 6.9 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.4 | 6.7 | GO:0000145 | exocyst(GO:0000145) |
| 0.4 | 5.3 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.4 | 33.8 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.4 | 7.6 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.4 | 1.5 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.4 | 14.1 | GO:0032420 | stereocilium(GO:0032420) |
| 0.4 | 4.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.3 | 24.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.3 | 2.0 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.3 | 12.6 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.3 | 4.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.3 | 16.1 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.3 | 4.0 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.3 | 4.6 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.3 | 24.1 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.3 | 4.8 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.3 | 1.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.3 | 2.4 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.3 | 16.6 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.3 | 13.7 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.3 | 3.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.2 | 1.0 | GO:1990879 | CST complex(GO:1990879) |
| 0.2 | 5.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 10.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.2 | 1.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.2 | 6.3 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.2 | 10.8 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.2 | 28.1 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.2 | 3.5 | GO:0005922 | connexon complex(GO:0005922) |
| 0.2 | 4.7 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.2 | 26.1 | GO:0005814 | centriole(GO:0005814) |
| 0.2 | 28.0 | GO:0030426 | growth cone(GO:0030426) |
| 0.2 | 4.8 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.2 | 6.1 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.2 | 10.6 | GO:0043235 | receptor complex(GO:0043235) |
| 0.2 | 15.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.2 | 3.6 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.2 | 6.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 6.7 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.2 | 9.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.1 | 3.3 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.1 | 10.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.1 | 0.7 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 27.1 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 6.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 12.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 4.9 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.1 | 0.5 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.1 | 0.8 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 12.9 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 9.3 | GO:0031514 | motile cilium(GO:0031514) |
| 0.1 | 0.6 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.1 | 0.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 3.1 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 0.3 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 1.6 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 27.6 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 0.9 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.1 | 6.5 | GO:0098793 | presynapse(GO:0098793) |
| 0.1 | 1.8 | GO:0043679 | axon terminus(GO:0043679) |
| 0.1 | 0.9 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 1.3 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 1.0 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 1.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 5.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 4.7 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.0 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.0 | 7.9 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 1.9 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 2.9 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 1.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 3.2 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.0 | 7.9 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 1.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.3 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 1.5 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 5.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 1.2 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 29.2 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 0.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 1.7 | GO:0043025 | neuronal cell body(GO:0043025) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.4 | 28.1 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 4.1 | 12.2 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 3.6 | 10.9 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 2.8 | 17.0 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 2.6 | 12.8 | GO:0052842 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 2.4 | 17.1 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 2.2 | 11.2 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 2.2 | 19.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 2.0 | 14.3 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 2.0 | 6.1 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 2.0 | 6.0 | GO:0070704 | C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704) |
| 1.7 | 5.0 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
| 1.6 | 17.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 1.5 | 12.2 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 1.5 | 6.0 | GO:0003867 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 1.5 | 7.3 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 1.4 | 14.4 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 1.4 | 17.3 | GO:0008430 | selenium binding(GO:0008430) |
| 1.4 | 12.9 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 1.4 | 21.2 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577) |
| 1.4 | 4.2 | GO:0086059 | voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059) |
| 1.3 | 4.0 | GO:0033746 | histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749) |
| 1.3 | 4.0 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 1.3 | 9.0 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 1.3 | 11.5 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 1.2 | 4.8 | GO:0035473 | lipase binding(GO:0035473) |
| 1.1 | 3.3 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 1.1 | 15.3 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 1.1 | 18.4 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 1.0 | 6.1 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 1.0 | 3.9 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 1.0 | 16.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 1.0 | 12.6 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.9 | 19.5 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.9 | 2.7 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.9 | 3.5 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.9 | 13.8 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.8 | 2.5 | GO:0050405 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405) |
| 0.8 | 11.5 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.8 | 6.4 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.8 | 5.4 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.8 | 5.3 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.7 | 19.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.7 | 3.7 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.7 | 3.6 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.7 | 4.3 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.7 | 2.1 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.7 | 22.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.7 | 4.1 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.7 | 2.0 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.7 | 9.5 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.7 | 6.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.7 | 2.0 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.6 | 22.6 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.6 | 3.1 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.6 | 6.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.6 | 1.8 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
| 0.6 | 9.1 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.6 | 9.9 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.5 | 17.0 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.5 | 2.2 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.5 | 20.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.5 | 6.5 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.5 | 9.2 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.5 | 28.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.5 | 1.6 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.5 | 3.0 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.5 | 7.6 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.5 | 12.7 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.5 | 4.2 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.5 | 6.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.5 | 4.1 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.5 | 7.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.5 | 5.9 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.4 | 3.8 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.4 | 3.8 | GO:0043426 | MRF binding(GO:0043426) |
| 0.4 | 1.6 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.4 | 4.5 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.4 | 1.6 | GO:0070905 | serine binding(GO:0070905) |
| 0.4 | 11.8 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.4 | 7.4 | GO:0005522 | profilin binding(GO:0005522) |
| 0.4 | 6.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.4 | 11.2 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.4 | 7.3 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.4 | 7.1 | GO:0004970 | ionotropic glutamate receptor activity(GO:0004970) extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.4 | 4.9 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.3 | 34.4 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.3 | 11.9 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.3 | 14.8 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.3 | 6.3 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.3 | 3.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.3 | 13.2 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.3 | 0.6 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.3 | 0.8 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.3 | 0.8 | GO:0070039 | rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039) |
| 0.3 | 3.8 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.3 | 1.6 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.3 | 8.1 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.3 | 44.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.3 | 3.4 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.3 | 3.6 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.2 | 1.7 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.2 | 5.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 4.1 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.2 | 3.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 2.8 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 0.2 | 3.3 | GO:0046790 | virion binding(GO:0046790) |
| 0.2 | 5.9 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.2 | 19.1 | GO:0002039 | p53 binding(GO:0002039) |
| 0.2 | 2.6 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.2 | 3.6 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.2 | 11.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.2 | 4.2 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 5.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 6.1 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.2 | 4.2 | GO:0015929 | hexosaminidase activity(GO:0015929) |
| 0.2 | 2.0 | GO:0015386 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821) |
| 0.2 | 1.4 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.2 | 1.7 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.2 | 2.1 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.2 | 6.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.2 | 0.9 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.2 | 1.2 | GO:0016406 | carnitine O-acyltransferase activity(GO:0016406) |
| 0.2 | 20.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 6.1 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 1.6 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.2 | 4.5 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 3.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.2 | 4.4 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.2 | 5.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.2 | 6.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 7.4 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.1 | 2.1 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.1 | 2.5 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 0.7 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
| 0.1 | 3.4 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 8.9 | GO:0017022 | myosin binding(GO:0017022) |
| 0.1 | 3.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 3.3 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 0.5 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 18.6 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.1 | 9.1 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.1 | 1.4 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.1 | 5.4 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 0.3 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 0.1 | 4.9 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.1 | 8.5 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.1 | 1.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 7.9 | GO:0003774 | motor activity(GO:0003774) |
| 0.1 | 2.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 1.9 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.1 | 1.0 | GO:0043047 | single-stranded telomeric DNA binding(GO:0043047) |
| 0.1 | 0.3 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.1 | 2.8 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.5 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.1 | 32.2 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.1 | 1.3 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.1 | 0.7 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.1 | 3.4 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 9.8 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.1 | 8.4 | GO:0019902 | phosphatase binding(GO:0019902) |
| 0.0 | 21.1 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.0 | 7.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.3 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.0 | 5.1 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 9.5 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.0 | 0.8 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 2.6 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.3 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 2.8 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.7 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 4.5 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 3.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 4.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 1.1 | GO:0005518 | collagen binding(GO:0005518) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 13.1 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.6 | 26.5 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.5 | 5.8 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.4 | 12.2 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.3 | 2.4 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.3 | 24.4 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.3 | 12.6 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.3 | 4.9 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.3 | 15.9 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.3 | 6.0 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.2 | 9.8 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.2 | 5.3 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.2 | 8.9 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.2 | 14.0 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.2 | 16.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.2 | 10.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.2 | 7.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 9.7 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.2 | 1.8 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.2 | 16.5 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.2 | 10.2 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.2 | 8.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.2 | 6.1 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.2 | 5.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 3.6 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 5.9 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 5.0 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 2.0 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 1.4 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 2.1 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 15.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 5.9 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 3.3 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 8.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 3.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.6 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 17.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 2.1 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.9 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.1 | 1.9 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.1 | 0.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 9.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 3.6 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 1.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.6 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.7 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 3.9 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 3.6 | REACTOME SIGNALING BY EGFR IN CANCER | Genes involved in Signaling by EGFR in Cancer |
| 1.0 | 13.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.6 | 18.7 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.6 | 13.1 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.6 | 10.8 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.6 | 12.4 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.5 | 16.4 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.5 | 17.9 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.5 | 20.9 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.5 | 12.5 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.5 | 12.2 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.5 | 9.5 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.5 | 17.6 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.4 | 6.9 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.4 | 11.1 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.4 | 20.2 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.4 | 0.7 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.4 | 12.7 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.3 | 12.6 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.3 | 5.3 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.3 | 4.8 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.3 | 13.0 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.3 | 4.8 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.3 | 10.7 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 9.0 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.2 | 14.6 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.2 | 5.0 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 1.8 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.2 | 3.5 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.2 | 3.4 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.2 | 13.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.2 | 0.9 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.2 | 12.7 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.2 | 4.1 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 8.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.2 | 14.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.2 | 1.2 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.2 | 10.3 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.2 | 4.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 2.2 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.1 | 4.9 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.1 | 5.4 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 2.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 5.6 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 5.5 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.1 | 14.3 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 6.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 3.6 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 6.5 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 1.4 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 3.1 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 0.9 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 1.6 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 1.5 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 6.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 1.4 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.1 | 1.6 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 5.0 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 1.0 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 1.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.5 | REACTOME NEGATIVE REGULATION OF FGFR SIGNALING | Genes involved in Negative regulation of FGFR signaling |
| 0.0 | 0.4 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 1.2 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.7 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.3 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 6.5 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 1.4 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 0.3 | REACTOME SIGNALING BY FGFR1 MUTANTS | Genes involved in Signaling by FGFR1 mutants |
| 0.0 | 0.3 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 0.8 | REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | Genes involved in Transmission across Chemical Synapses |