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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UUUUUGC

Z-value: 0.24

Motif logo

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miRNA associated with seed UUUUUGC

NamemiRBASE accession
hsa-miR-129-5p
MIMAT0000242

Activity profile of UUUUUGC motif

Sorted Z-values of UUUUUGC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UUUUUGC

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_20486197 0.95 ENST00000375078.4
CAMK2N1
calcium/calmodulin dependent protein kinase II inhibitor 1
chr4_-_152536045 0.21 ENST00000603548.6
ENST00000281708.10
FBXW7
F-box and WD repeat domain containing 7
chr14_-_51096029 0.19 ENST00000298355.7
TRIM9
tripartite motif containing 9
chr17_-_28951285 0.18 ENST00000577226.5
PHF12
PHD finger protein 12
chr15_-_50765656 0.16 ENST00000261854.10
SPPL2A
signal peptide peptidase like 2A
chr8_+_42896883 0.15 ENST00000307602.9
HOOK3
hook microtubule tethering protein 3
chr22_+_39994926 0.14 ENST00000333407.11
FAM83F
family with sequence similarity 83 member F
chr9_+_112486819 0.11 ENST00000337530.11
KIAA1958
KIAA1958
chr13_+_57631735 0.10 ENST00000377918.8
PCDH17
protocadherin 17
chr5_+_126600913 0.10 ENST00000297540.5
PHAX
phosphorylated adaptor for RNA export
chr9_-_14314067 0.10 ENST00000397575.7
NFIB
nuclear factor I B
chr5_-_79512794 0.09 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
HOMER1
homer scaffold protein 1
chr3_+_181711915 0.07 ENST00000325404.3
SOX2
SRY-box transcription factor 2
chr2_-_152099023 0.06 ENST00000201943.10
ENST00000427385.6
ENST00000539935.7
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr2_+_167868948 0.06 ENST00000392690.3
B3GALT1
beta-1,3-galactosyltransferase 1
chrX_+_120250752 0.05 ENST00000326624.2
ENST00000557385.2
ZBTB33
zinc finger and BTB domain containing 33
chr10_+_110207587 0.05 ENST00000332674.9
ENST00000453116.5
MXI1
MAX interactor 1, dimerization protein
chr8_+_12945667 0.04 ENST00000524591.7
TRMT9B
tRNA methyltransferase 9B (putative)
chr5_-_133612524 0.04 ENST00000265342.12
FSTL4
follistatin like 4
chr4_-_170003738 0.04 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibril associated protein 3 like
chr2_-_25252251 0.04 ENST00000380746.8
ENST00000402667.1
DNMT3A
DNA methyltransferase 3 alpha
chr8_-_92103217 0.03 ENST00000615601.4
ENST00000523629.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr6_-_89412219 0.03 ENST00000369415.9
RRAGD
Ras related GTP binding D
chr22_-_36703723 0.03 ENST00000300105.7
CACNG2
calcium voltage-gated channel auxiliary subunit gamma 2
chr21_-_37916440 0.02 ENST00000609713.2
KCNJ6
potassium inwardly rectifying channel subfamily J member 6
chr12_+_51591216 0.02 ENST00000668547.1
ENST00000354534.11
ENST00000627620.5
ENST00000545061.5
SCN8A
sodium voltage-gated channel alpha subunit 8
chr7_-_92833896 0.02 ENST00000265734.8
CDK6
cyclin dependent kinase 6
chr3_-_120094436 0.00 ENST00000264235.13
ENST00000677034.1
GSK3B
glycogen synthase kinase 3 beta
chr8_+_55102012 0.00 ENST00000327381.7
XKR4
XK related 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.0 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)