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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for VENTX

Z-value: 1.25

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Transcription factors associated with VENTX

Gene Symbol Gene ID Gene Info
VENTX
ENSG00000151650.8 VENTX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VENTXhg38_v1_chr10_+_133237849_1332378630.351.1e-07Click!

Activity profile of VENTX motif

Sorted Z-values of VENTX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of VENTX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_92323154 10.01 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
SLC24A4
solute carrier family 24 member 4
chr12_+_25052732 5.69 ENST00000547044.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr6_-_32668368 5.13 ENST00000399084.5
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr6_-_49713564 5.09 ENST00000616725.4
ENST00000618917.4
CRISP2
cysteine rich secretory protein 2
chr12_+_25052512 4.99 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr12_+_25052634 4.89 ENST00000548766.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr6_-_49713521 4.72 ENST00000339139.5
CRISP2
cysteine rich secretory protein 2
chr10_-_28282086 4.28 ENST00000375719.7
ENST00000375732.5
MPP7
membrane palmitoylated protein 7
chr4_-_83114715 3.99 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
PLAC8
placenta associated 8
chr6_-_99425269 3.95 ENST00000647811.1
ENST00000481229.2
ENST00000369239.10
ENST00000681611.1
ENST00000681615.1
ENST00000438806.5
PNISR
PNN interacting serine and arginine rich protein
chr8_-_33567118 3.68 ENST00000256257.2
RNF122
ring finger protein 122
chr12_-_6124662 3.64 ENST00000261405.10
VWF
von Willebrand factor
chr18_-_76495191 2.78 ENST00000443185.7
ZNF516
zinc finger protein 516
chr19_-_49119092 2.53 ENST00000408991.4
C19orf73
chromosome 19 open reading frame 73
chr2_+_202912214 2.51 ENST00000402905.7
ENST00000320443.12
ENST00000414490.5
ENST00000431787.5
ENST00000444724.5
ENST00000414857.5
ENST00000438828.4
ENST00000430899.5
ENST00000445120.5
ENST00000441569.5
ENST00000432024.5
ENST00000443740.5
ENST00000414439.5
ENST00000428585.5
ENST00000447539.5
ENST00000434998.5
CARF
calcium responsive transcription factor
chr15_+_33968484 2.50 ENST00000383263.7
CHRM5
cholinergic receptor muscarinic 5
chr8_-_86743626 2.44 ENST00000320005.6
CNGB3
cyclic nucleotide gated channel subunit beta 3
chr18_-_55586092 2.39 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
TCF4
transcription factor 4
chr10_+_84194527 2.38 ENST00000623527.4
CDHR1
cadherin related family member 1
chr18_-_55585773 2.15 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
TCF4
transcription factor 4
chr9_-_23826231 2.08 ENST00000397312.7
ELAVL2
ELAV like RNA binding protein 2
chr14_-_26597430 2.07 ENST00000344429.9
ENST00000574031.1
ENST00000465357.6
ENST00000547619.5
NOVA1
NOVA alternative splicing regulator 1
chr2_+_44941695 2.05 ENST00000260653.5
SIX3
SIX homeobox 3
chr13_+_108629605 1.97 ENST00000457511.7
MYO16
myosin XVI
chr6_-_39725387 1.95 ENST00000287152.12
KIF6
kinesin family member 6
chr2_-_207167220 1.92 ENST00000421199.5
ENST00000457962.5
KLF7
Kruppel like factor 7
chr12_+_52301833 1.89 ENST00000293525.5
KRT86
keratin 86
chr18_+_31591869 1.85 ENST00000237014.8
TTR
transthyretin
chr12_-_101210232 1.83 ENST00000536262.3
SLC5A8
solute carrier family 5 member 8
chr12_+_80716906 1.82 ENST00000228644.4
MYF5
myogenic factor 5
chr14_+_32329256 1.77 ENST00000280979.9
AKAP6
A-kinase anchoring protein 6
chr2_-_162152404 1.74 ENST00000375497.3
GCG
glucagon
chr11_+_46701010 1.66 ENST00000311764.3
ZNF408
zinc finger protein 408
chr14_+_32329341 1.61 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr4_-_76007501 1.55 ENST00000264888.6
CXCL9
C-X-C motif chemokine ligand 9
chr20_+_43507668 1.54 ENST00000434666.5
ENST00000649084.1
ENST00000418998.7
ENST00000427442.8
ENST00000649917.1
L3MBTL1
L3MBTL histone methyl-lysine binding protein 1
chr3_+_134795248 1.50 ENST00000398015.8
EPHB1
EPH receptor B1
chr9_+_130664594 1.50 ENST00000253008.3
ENST00000676323.1
PRDM12
PR/SET domain 12
chr18_+_61333424 1.46 ENST00000262717.9
CDH20
cadherin 20
chrX_-_131289266 1.44 ENST00000370910.5
ENST00000370901.4
ENST00000361420.8
ENST00000370903.8
IGSF1
immunoglobulin superfamily member 1
chrX_-_140505058 1.40 ENST00000370536.5
SOX3
SRY-box transcription factor 3
chr22_-_40533808 1.35 ENST00000422851.1
ENST00000651694.1
ENST00000652095.2
MRTFA
myocardin related transcription factor A
chr2_+_176157293 1.35 ENST00000683222.1
HOXD3
homeobox D3
chr2_+_170178136 1.32 ENST00000409044.7
ENST00000408978.9
MYO3B
myosin IIIB
chr12_-_52434363 1.31 ENST00000252245.6
KRT75
keratin 75
chr8_+_49911396 1.29 ENST00000642720.2
SNTG1
syntrophin gamma 1
chr18_+_44700796 1.27 ENST00000677130.1
SETBP1
SET binding protein 1
chr6_+_101398788 1.25 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr12_-_51217671 1.25 ENST00000333640.11
ENST00000550824.6
POU6F1
POU class 6 homeobox 1
chr3_+_134795277 1.24 ENST00000647596.1
EPHB1
EPH receptor B1
chr7_+_90709816 1.23 ENST00000436577.3
CDK14
cyclin dependent kinase 14
chr18_+_13465009 1.22 ENST00000593236.1
ENST00000678400.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr1_+_174447944 1.18 ENST00000367685.5
GPR52
G protein-coupled receptor 52
chr4_+_70721953 1.17 ENST00000381006.8
ENST00000226328.8
RUFY3
RUN and FYVE domain containing 3
chr1_+_61952283 1.17 ENST00000307297.8
PATJ
PATJ crumbs cell polarity complex component
chr14_-_81533800 1.14 ENST00000555824.5
ENST00000557372.1
ENST00000336735.9
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
chr14_+_64704380 1.13 ENST00000247226.13
ENST00000394691.7
PLEKHG3
pleckstrin homology and RhoGEF domain containing G3
chr12_-_102197827 1.11 ENST00000329406.5
PMCH
pro-melanin concentrating hormone
chr8_-_102412740 1.11 ENST00000521922.5
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr12_+_56080126 1.10 ENST00000411731.6
ERBB3
erb-b2 receptor tyrosine kinase 3
chr4_+_89901979 1.10 ENST00000508372.1
MMRN1
multimerin 1
chr10_-_60572599 1.09 ENST00000503366.5
ANK3
ankyrin 3
chr4_-_26490453 1.08 ENST00000295589.4
CCKAR
cholecystokinin A receptor
chr8_+_31639291 1.04 ENST00000651149.1
ENST00000650866.1
NRG1
neuregulin 1
chr3_+_171843337 1.04 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
TMEM212
transmembrane protein 212
chr12_+_111034136 1.00 ENST00000261726.11
CUX2
cut like homeobox 2
chr11_+_13962676 0.99 ENST00000576479.4
SPON1
spondin 1
chr8_-_102412686 0.98 ENST00000220959.8
ENST00000520539.6
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr9_+_79572572 0.95 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE4
TLE family member 4, transcriptional corepressor
chr1_+_61952036 0.94 ENST00000646453.1
ENST00000635137.1
PATJ
PATJ crumbs cell polarity complex component
chr2_-_164842140 0.93 ENST00000496396.1
ENST00000629362.2
ENST00000445474.2
ENST00000483743.6
COBLL1
cordon-bleu WH2 repeat protein like 1
chr20_-_52105644 0.92 ENST00000371523.8
ZFP64
ZFP64 zinc finger protein
chr4_+_70592253 0.91 ENST00000322937.10
ENST00000613447.4
AMBN
ameloblastin
chr3_+_186666003 0.88 ENST00000232003.5
HRG
histidine rich glycoprotein
chr8_+_49911604 0.85 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
SNTG1
syntrophin gamma 1
chr4_+_70592295 0.85 ENST00000449493.2
AMBN
ameloblastin
chr3_-_57226344 0.83 ENST00000495160.2
HESX1
HESX homeobox 1
chr11_+_22338333 0.82 ENST00000263160.4
SLC17A6
solute carrier family 17 member 6
chr17_+_41688879 0.80 ENST00000469257.2
ENST00000591776.5
EIF1
eukaryotic translation initiation factor 1
chr22_+_38705922 0.80 ENST00000216044.10
GTPBP1
GTP binding protein 1
chr11_-_36598221 0.79 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
RAG2
recombination activating 2
chr2_+_168901290 0.73 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
G6PC2
glucose-6-phosphatase catalytic subunit 2
chr10_-_48605032 0.73 ENST00000249601.9
ARHGAP22
Rho GTPase activating protein 22
chr7_-_83162899 0.72 ENST00000423517.6
PCLO
piccolo presynaptic cytomatrix protein
chr4_+_112860981 0.68 ENST00000671704.1
ANK2
ankyrin 2
chr17_-_10469558 0.67 ENST00000255381.2
MYH4
myosin heavy chain 4
chr2_-_88861258 0.65 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr2_-_165203870 0.65 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr14_+_64986846 0.58 ENST00000246166.3
FNTB
farnesyltransferase, CAAX box, beta
chr1_+_150364136 0.58 ENST00000369068.5
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chrX_+_55452119 0.58 ENST00000342972.3
MAGEH1
MAGE family member H1
chr7_+_18495723 0.53 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
HDAC9
histone deacetylase 9
chr7_-_108240049 0.53 ENST00000379022.8
NRCAM
neuronal cell adhesion molecule
chr4_+_112860912 0.51 ENST00000671951.1
ANK2
ankyrin 2
chrX_+_78747705 0.51 ENST00000614823.5
ENST00000435339.3
ENST00000514744.5
LPAR4
lysophosphatidic acid receptor 4
chr7_+_90709530 0.51 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr17_-_48968587 0.49 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr8_+_31639222 0.48 ENST00000519301.6
ENST00000652698.1
NRG1
neuregulin 1
chr1_+_186296267 0.48 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
PRG4
proteoglycan 4
chr7_+_90709231 0.46 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr3_-_165078480 0.45 ENST00000264382.8
SI
sucrase-isomaltase
chr4_+_112861053 0.44 ENST00000672221.1
ANK2
ankyrin 2
chr6_-_75493629 0.41 ENST00000393004.6
FILIP1
filamin A interacting protein 1
chr22_-_30574572 0.40 ENST00000402369.5
GAL3ST1
galactose-3-O-sulfotransferase 1
chr6_-_89819699 0.35 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
MDN1
midasin AAA ATPase 1
chr2_-_164842011 0.34 ENST00000409184.8
ENST00000456693.5
COBLL1
cordon-bleu WH2 repeat protein like 1
chr17_-_41065879 0.33 ENST00000394015.3
KRTAP2-4
keratin associated protein 2-4
chr13_-_103066411 0.32 ENST00000245312.5
SLC10A2
solute carrier family 10 member 2
chr2_-_223602284 0.32 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
SCG2
secretogranin II
chr6_+_151690492 0.30 ENST00000404742.5
ENST00000440973.5
ESR1
estrogen receptor 1
chr11_+_75815180 0.29 ENST00000356136.8
UVRAG
UV radiation resistance associated
chrX_+_136648214 0.28 ENST00000370628.2
CD40LG
CD40 ligand
chrX_+_136648138 0.25 ENST00000370629.7
CD40LG
CD40 ligand
chr1_+_168280872 0.25 ENST00000367821.8
TBX19
T-box transcription factor 19
chr17_-_352784 0.25 ENST00000577079.5
ENST00000331302.12
ENST00000618002.4
ENST00000536489.6
RPH3AL
rabphilin 3A like (without C2 domains)
chr14_+_64715677 0.25 ENST00000634379.2
PLEKHG3
pleckstrin homology and RhoGEF domain containing G3
chr4_-_154590735 0.24 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
FGA
fibrinogen alpha chain
chr9_+_113463697 0.24 ENST00000317613.10
RGS3
regulator of G protein signaling 3
chr9_+_133636355 0.19 ENST00000393056.8
DBH
dopamine beta-hydroxylase
chr13_-_26221703 0.18 ENST00000381570.7
ENST00000346166.7
RNF6
ring finger protein 6
chr7_+_151048526 0.16 ENST00000349064.10
ASIC3
acid sensing ion channel subunit 3
chr12_-_86256267 0.14 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr3_-_57199938 0.10 ENST00000473921.2
ENST00000295934.8
HESX1
HESX homeobox 1
chr5_-_157059109 0.05 ENST00000523175.6
ENST00000522693.5
HAVCR1
hepatitis A virus cellular receptor 1
chr17_-_50707855 0.04 ENST00000285243.7
ANKRD40
ankyrin repeat domain 40

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.7 4.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.7 2.1 GO:1902866 neuroblast differentiation(GO:0014016) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.6 3.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5 10.0 GO:0097186 amelogenesis(GO:0097186)
0.5 2.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.4 1.7 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.4 1.5 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.3 1.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 2.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.3 1.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 2.5 GO:0035865 cellular response to potassium ion(GO:0035865)
0.2 0.7 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 4.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 0.9 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 2.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 0.8 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.2 1.6 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 1.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 3.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.5 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 1.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.8 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.5 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.6 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.8 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 2.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 2.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 5.7 GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response(GO:0002381)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.9 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.4 GO:0007530 sex determination(GO:0007530)
0.0 1.0 GO:0007614 short-term memory(GO:0007614)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891) sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 1.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 2.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 1.5 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 1.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.8 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 4.5 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 2.0 GO:0021549 cerebellum development(GO:0021549)
0.0 1.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 3.2 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0019228 neuronal action potential(GO:0019228)
0.0 1.3 GO:0007631 feeding behavior(GO:0007631)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4 3.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3 5.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 3.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.7 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.2 1.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 4.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 2.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.6 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 2.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 2.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.6 GO:0043194 axon initial segment(GO:0043194)
0.0 5.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 4.0 GO:0016459 myosin complex(GO:0016459)
0.0 1.6 GO:0043034 costamere(GO:0043034)
0.0 1.2 GO:0071437 invadopodium(GO:0071437)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.9 GO:0036019 endolysosome(GO:0036019)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 4.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 4.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 5.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 1.5 GO:0032093 SAM domain binding(GO:0032093)
0.5 2.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 2.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.4 5.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 2.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 1.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 0.7 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 1.8 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 4.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 3.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 1.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.6 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 4.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 2.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 1.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 2.2 GO:0030332 cyclin binding(GO:0030332)
0.0 2.7 GO:0030507 spectrin binding(GO:0030507)
0.0 5.9 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 3.8 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 2.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 2.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.1 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 7.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 7.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 6.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 11.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors