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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for XBP1

Z-value: 5.79

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Transcription factors associated with XBP1

Gene Symbol Gene ID Gene Info
XBP1
ENSG00000100219.16 XBP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
XBP1hg38_v1_chr22_-_28800042_28800133,
hg38_v1_chr22_-_28800558_28800597		0.384.8e-09Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_172040554 93.90 ENST00000336824.8
ENST00000423424.5
FNDC3B
fibronectin type III domain containing 3B
chr3_+_33114033 78.42 ENST00000449224.1
CRTAP
cartilage associated protein
chr3_-_57597443 68.66 ENST00000463880.1
ARF4
ADP ribosylation factor 4
chr15_-_60398733 66.96 ENST00000559818.6
ANXA2
annexin A2
chr1_-_23799533 59.92 ENST00000429356.5
GALE
UDP-galactose-4-epimerase
chr15_-_60397964 52.17 ENST00000558998.5
ENST00000560165.5
ENST00000557986.5
ENST00000559467.5
ENST00000677968.1
ENST00000678450.1
ENST00000332680.8
ENST00000396024.7
ENST00000557906.6
ENST00000558558.6
ENST00000559113.6
ENST00000559780.6
ENST00000559956.6
ENST00000560468.6
ENST00000678870.1
ENST00000678061.1
ENST00000451270.7
ENST00000421017.6
ENST00000560466.5
ENST00000558132.5
ENST00000559370.5
ENST00000559725.5
ENST00000558985.6
ENST00000679109.1
ANXA2
annexin A2
chr3_-_57597325 50.46 ENST00000496292.5
ENST00000489843.1
ENST00000303436.11
ARF4
ADP ribosylation factor 4
chr3_+_128052390 45.99 ENST00000481210.5
ENST00000243253.8
SEC61A1
SEC61 translocon subunit alpha 1
chr15_+_79311084 40.92 ENST00000299705.10
TMED3
transmembrane p24 trafficking protein 3
chr7_+_128739395 38.23 ENST00000479257.5
CALU
calumenin
chr7_+_94394886 37.81 ENST00000297268.11
ENST00000620463.1
COL1A2
collagen type I alpha 2 chain
chr2_-_69387188 37.53 ENST00000674507.1
ENST00000357308.9
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr7_+_128739292 37.49 ENST00000535011.6
ENST00000542996.6
ENST00000249364.9
ENST00000449187.6
CALU
calumenin
chr6_+_63211446 36.34 ENST00000370659.1
FKBP1C
FKBP prolyl isomerase family member 1C
chr7_-_6484057 34.96 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDELR2
DAGLB
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chr3_+_133805789 33.86 ENST00000678299.1
SRPRB
SRP receptor subunit beta
chr2_+_170929198 33.79 ENST00000234160.5
GORASP2
golgi reassembly stacking protein 2
chr12_-_55729660 33.16 ENST00000546457.1
ENST00000549117.5
CD63
CD63 molecule
chr12_-_108731505 33.00 ENST00000261401.8
ENST00000552871.5
CORO1C
coronin 1C
chr3_-_128650800 32.23 ENST00000296255.8
RPN1
ribophorin I
chr3_-_10321041 31.90 ENST00000397109.7
ENST00000428626.5
ENST00000445064.1
ENST00000431352.1
ENST00000397117.5
ENST00000337354.8
ENST00000383801.6
ENST00000432213.1
ENST00000350697.8
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component
chr2_-_69387241 31.54 ENST00000361060.5
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr5_-_10761156 30.48 ENST00000432074.2
ENST00000230895.11
DAP
death associated protein
chr3_+_105367212 29.65 ENST00000472644.6
ALCAM
activated leukocyte cell adhesion molecule
chr19_+_16077006 29.37 ENST00000586833.7
ENST00000642221.1
TPM4
tropomyosin 4
chr9_+_111631354 29.28 ENST00000374294.3
DNAJC25-GNG10
DNAJC25-GNG10 readthrough
chr2_+_241315092 28.92 ENST00000391973.6
SEPTIN2
septin 2
chr2_-_99336306 28.04 ENST00000264255.8
ENST00000409434.5
ENST00000434323.5
TXNDC9
thioredoxin domain containing 9
chr8_-_63026179 27.87 ENST00000677919.1
GGH
gamma-glutamyl hydrolase
chr8_-_123042122 27.37 ENST00000405944.7
DERL1
derlin 1
chr11_-_66289125 27.29 ENST00000471387.6
ENST00000376901.9
ENST00000359461.10
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein
chr2_-_20051610 27.05 ENST00000175091.5
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr1_-_45522870 26.98 ENST00000424390.2
PRDX1
peroxiredoxin 1
chr2_-_33599269 26.77 ENST00000431950.1
ENST00000403368.1
ENST00000238823.13
FAM98A
family with sequence similarity 98 member A
chr21_-_17612842 26.37 ENST00000339775.10
ENST00000348354.7
BTG3
BTG anti-proliferation factor 3
chr5_+_115841878 26.04 ENST00000316788.12
AP3S1
adaptor related protein complex 3 subunit sigma 1
chr1_-_11060000 25.96 ENST00000376957.7
SRM
spermidine synthase
chr2_-_69387130 25.81 ENST00000674438.1
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr11_+_32091065 25.68 ENST00000054950.4
RCN1
reticulocalbin 1
chr19_-_4670331 24.92 ENST00000262947.8
ENST00000599630.1
MYDGF
myeloid derived growth factor
chr1_-_86914102 23.29 ENST00000331835.10
ENST00000401030.4
ENST00000370554.5
SELENOF
selenoprotein F
chr8_+_97644164 22.64 ENST00000336273.8
MTDH
metadherin
chr2_+_241315223 22.59 ENST00000428282.5
ENST00000360051.7
SEPTIN2
septin 2
chr4_-_118836067 22.13 ENST00000280551.11
SEC24D
SEC24 homolog D, COPII coat complex component
chr1_-_86914319 22.00 ENST00000611507.4
ENST00000616787.4
SELENOF
selenoprotein F
chr17_+_38870050 21.97 ENST00000318008.11
ENST00000435347.7
LASP1
LIM and SH3 protein 1
chr20_+_58891981 21.47 ENST00000488652.6
ENST00000476935.6
ENST00000492907.6
ENST00000603546.2
GNAS
GNAS complex locus
chr6_-_109381739 21.45 ENST00000504373.2
CD164
CD164 molecule
chr12_-_106247950 21.30 ENST00000378026.5
CKAP4
cytoskeleton associated protein 4
chr6_+_116370938 20.12 ENST00000644252.3
ENST00000646710.1
ENST00000359564.3
DSE
dermatan sulfate epimerase
chr5_-_122078249 19.94 ENST00000231004.5
LOX
lysyl oxidase
chr17_+_15945101 19.89 ENST00000304222.3
ADORA2B
adenosine A2b receptor
chr8_-_123042244 19.50 ENST00000259512.9
ENST00000419562.6
DERL1
derlin 1
chr14_-_24195570 19.50 ENST00000530468.5
ENST00000528010.1
ENST00000396854.8
ENST00000524835.5
ENST00000525592.1
TM9SF1
transmembrane 9 superfamily member 1
chr2_+_84905644 19.04 ENST00000233143.6
TMSB10
thymosin beta 10
chr18_-_49491586 18.68 ENST00000584895.5
ENST00000580210.5
ENST00000579408.5
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr14_-_24195334 18.65 ENST00000530563.1
ENST00000528895.5
ENST00000528669.5
ENST00000532632.1
ENST00000261789.9
TM9SF1
transmembrane 9 superfamily member 1
chr7_+_16753731 18.40 ENST00000262067.5
TSPAN13
tetraspanin 13
chr21_+_43719095 18.36 ENST00000468090.5
ENST00000291565.9
PDXK
pyridoxal kinase
chr2_-_241315180 18.27 ENST00000441124.5
ENST00000391976.6
HDLBP
high density lipoprotein binding protein
chr11_+_17276708 18.06 ENST00000531172.5
ENST00000529010.6
ENST00000533738.6
ENST00000323688.10
NUCB2
nucleobindin 2
chr9_+_35732649 17.95 ENST00000353704.3
CREB3
cAMP responsive element binding protein 3
chr10_+_87659839 17.12 ENST00000456849.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr22_+_38468036 16.63 ENST00000409006.3
ENST00000216014.9
KDELR3
KDEL endoplasmic reticulum protein retention receptor 3
chr20_+_45416084 16.63 ENST00000279035.14
ENST00000543458.7
ENST00000372689.9
ENST00000639499.1
ENST00000279036.12
ENST00000638594.1
ENST00000638489.1
ENST00000638353.1
ENST00000639382.1
ENST00000640210.1
ENST00000639235.1
ENST00000638478.1
ENST00000432270.2
ENST00000545755.3
ENST00000640324.1
PIGT
phosphatidylinositol glycan anchor biosynthesis class T
chr9_-_35072588 16.61 ENST00000677257.1
ENST00000679862.1
ENST00000679902.1
ENST00000358901.11
ENST00000681335.1
ENST00000681386.1
ENST00000679647.1
ENST00000448530.6
VCP
valosin containing protein
chrX_+_153794635 16.55 ENST00000370086.8
ENST00000370085.3
SSR4
signal sequence receptor subunit 4
chr17_-_42423246 16.43 ENST00000357037.6
CAVIN1
caveolae associated protein 1
chr7_-_30026617 16.31 ENST00000222803.10
FKBP14
FKBP prolyl isomerase 14
chr1_+_161153968 15.77 ENST00000368003.6
UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr14_-_49620594 15.71 ENST00000298289.7
RPL36AL
ribosomal protein L36a like
chr17_-_15563428 15.11 ENST00000584811.5
ENST00000419890.3
ENST00000518321.6
ENST00000438826.7
ENST00000225576.7
ENST00000428082.6
ENST00000522212.6
TVP23C
TVP23C-CDRT4
trans-golgi network vesicle protein 23 homolog C
TVP23C-CDRT4 readthrough
chr9_-_35732122 14.80 ENST00000314888.10
TLN1
talin 1
chr19_-_8005590 14.71 ENST00000407627.7
ENST00000593807.1
ELAVL1
ELAV like RNA binding protein 1
chr20_+_32819942 14.69 ENST00000375571.6
MAPRE1
microtubule associated protein RP/EB family member 1
chr9_-_35072561 14.08 ENST00000678650.1
VCP
valosin containing protein
chrX_-_41922992 13.91 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
CASK
calcium/calmodulin dependent serine protein kinase
chr13_-_30465923 13.87 ENST00000341423.10
ENST00000326004.4
HMGB1
high mobility group box 1
chr9_+_99222258 13.86 ENST00000223641.5
SEC61B
SEC61 translocon subunit beta
chr3_-_177196451 13.45 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1XR1
TBL1X receptor 1
chr11_-_119057185 13.45 ENST00000614668.4
ENST00000617285.5
HYOU1
hypoxia up-regulated 1
chrX_+_153794152 13.45 ENST00000370087.5
SSR4
signal sequence receptor subunit 4
chr19_-_18919348 13.43 ENST00000349893.8
ENST00000351079.8
ENST00000600932.5
ENST00000262812.9
COPE
COPI coat complex subunit epsilon
chr10_-_70170466 13.39 ENST00000373239.2
ENST00000373241.9
ENST00000373242.6
SAR1A
secretion associated Ras related GTPase 1A
chr11_+_207688 13.14 ENST00000526104.6
RIC8A
RIC8 guanine nucleotide exchange factor A
chr11_-_119057218 13.13 ENST00000652093.1
HYOU1
hypoxia up-regulated 1
chr11_+_66052331 13.03 ENST00000528302.5
ENST00000322535.11
ENST00000524627.5
ENST00000533595.5
ENST00000530322.5
SF3B2
splicing factor 3b subunit 2
chr2_+_27032938 13.02 ENST00000238788.14
ENST00000404032.7
TMEM214
transmembrane protein 214
chr3_+_184315347 12.79 ENST00000424196.5
EIF4G1
eukaryotic translation initiation factor 4 gamma 1
chr2_-_241315652 12.74 ENST00000310931.10
ENST00000413241.5
ENST00000423693.5
ENST00000428482.5
ENST00000420451.5
ENST00000417540.5
HDLBP
high density lipoprotein binding protein
chrX_+_47190836 12.67 ENST00000377351.8
UBA1
ubiquitin like modifier activating enzyme 1
chr11_-_119057105 12.53 ENST00000534233.5
ENST00000614711.4
ENST00000530467.5
ENST00000621959.4
ENST00000532519.6
ENST00000532421.5
ENST00000610597.1
ENST00000612687.4
HYOU1
hypoxia up-regulated 1
chr11_-_62646598 12.16 ENST00000648273.1
ENST00000356638.8
ENST00000346178.8
ENST00000534779.5
ENST00000525994.1
ENST00000540933.5
GANAB
glucosidase II alpha subunit
chr11_-_119101814 12.09 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
DPAGT1
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr7_-_128405930 12.05 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
IMPDH1
inosine monophosphate dehydrogenase 1
chr20_+_45416551 11.83 ENST00000639292.1
PIGT
phosphatidylinositol glycan anchor biosynthesis class T
chr3_+_33114007 11.72 ENST00000320954.11
CRTAP
cartilage associated protein
chr18_-_49492305 11.70 ENST00000615479.4
ENST00000583637.5
ENST00000618613.5
ENST00000615760.4
ENST00000578528.1
ENST00000578532.5
ENST00000580387.5
ENST00000579248.5
ENST00000580261.6
ENST00000581373.5
ENST00000618619.4
ENST00000617346.4
ENST00000583036.5
ENST00000332968.11
RPL17
RPL17-C18orf32
ribosomal protein L17
RPL17-C18orf32 readthrough
chr11_-_93543382 11.32 ENST00000298966.7
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr11_+_118572373 11.04 ENST00000392859.7
ENST00000264028.5
ENST00000614498.4
ENST00000359415.8
ENST00000534182.2
ARCN1
archain 1
chr1_+_109984756 10.93 ENST00000393614.8
ENST00000369799.10
AHCYL1
adenosylhomocysteinase like 1
chr5_+_120464236 10.73 ENST00000407149.7
ENST00000379551.2
PRR16
proline rich 16
chr9_-_35689913 10.39 ENST00000329305.6
ENST00000645482.3
ENST00000647435.1
ENST00000378292.9
TPM2
tropomyosin 2
chr4_-_75724386 10.38 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP2
G3BP stress granule assembly factor 2
chr4_-_82429402 10.10 ENST00000602300.5
HNRNPDL
heterogeneous nuclear ribonucleoprotein D like
chr4_-_158723355 9.93 ENST00000307720.4
PPID
peptidylprolyl isomerase D
chr14_+_99793329 9.61 ENST00000334192.8
EML1
EMAP like 1
chr11_-_68271896 9.40 ENST00000533310.5
ENST00000304271.11
ENST00000527280.1
C11orf24
chromosome 11 open reading frame 24
chr10_+_73744346 8.68 ENST00000345254.9
ENST00000339365.2
SEC24C
SEC24 homolog C, COPII coat complex component
chr4_-_75724362 8.22 ENST00000677583.1
G3BP2
G3BP stress granule assembly factor 2
chr3_+_132659897 8.12 ENST00000493720.6
UBA5
ubiquitin like modifier activating enzyme 5
chr19_+_7637099 7.73 ENST00000595950.5
ENST00000221283.10
ENST00000441779.6
ENST00000414284.6
STXBP2
syntaxin binding protein 2
chr16_-_11797208 7.69 ENST00000571198.5
ENST00000572781.5
ENST00000355758.9
ZC3H7A
zinc finger CCCH-type containing 7A
chr19_+_54115726 7.65 ENST00000445811.5
ENST00000321030.9
ENST00000445124.5
ENST00000447810.5
PRPF31
pre-mRNA processing factor 31
chr22_-_42857194 7.32 ENST00000437119.6
ENST00000454099.5
ENST00000263245.10
ARFGAP3
ADP ribosylation factor GTPase activating protein 3
chr2_-_169573766 7.32 ENST00000438035.5
ENST00000453929.6
FASTKD1
FAST kinase domains 1
chr4_+_75724569 6.96 ENST00000514213.7
ENST00000264904.8
USO1
USO1 vesicle transport factor
chrX_+_154398890 6.95 ENST00000406022.6
RPL10
ribosomal protein L10
chr5_+_154858218 6.91 ENST00000523698.5
ENST00000517876.5
ENST00000520472.5
CNOT8
CCR4-NOT transcription complex subunit 8
chr18_-_36828730 6.89 ENST00000587382.5
TPGS2
tubulin polyglutamylase complex subunit 2
chr20_+_25248036 6.85 ENST00000216962.9
PYGB
glycogen phosphorylase B
chr7_+_127652186 6.46 ENST00000354725.8
SND1
staphylococcal nuclease and tudor domain containing 1
chr6_+_33200860 6.43 ENST00000374677.8
SLC39A7
solute carrier family 39 member 7
chr5_+_154858594 6.21 ENST00000519430.5
ENST00000520671.5
ENST00000521583.5
ENST00000285896.11
ENST00000518028.5
ENST00000519404.5
ENST00000519394.5
ENST00000518775.5
CNOT8
CCR4-NOT transcription complex subunit 8
chr5_+_154858482 6.18 ENST00000519211.5
ENST00000522458.5
ENST00000519903.5
ENST00000521450.5
ENST00000403027.6
CNOT8
CCR4-NOT transcription complex subunit 8
chr6_+_33200820 6.02 ENST00000374675.7
SLC39A7
solute carrier family 39 member 7
chr19_+_49851205 5.98 ENST00000601675.5
PTOV1
PTOV1 extended AT-hook containing adaptor protein
chr6_-_107958165 5.81 ENST00000369002.9
SEC63
SEC63 homolog, protein translocation regulator
chr14_+_99793375 5.81 ENST00000262233.11
ENST00000556714.5
EML1
EMAP like 1
chr6_-_106325616 5.64 ENST00000360666.6
ATG5
autophagy related 5
chr3_+_50246888 5.48 ENST00000451956.1
GNAI2
G protein subunit alpha i2
chr19_+_49851173 5.40 ENST00000599732.5
PTOV1
PTOV1 extended AT-hook containing adaptor protein
chr16_-_66925526 5.12 ENST00000299759.11
ENST00000420652.5
RRAD
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr19_+_49851136 5.03 ENST00000391842.5
PTOV1
PTOV1 extended AT-hook containing adaptor protein
chr18_-_36828939 4.90 ENST00000593035.5
ENST00000383056.7
ENST00000588909.1
ENST00000590337.5
ENST00000334295.9
TPGS2
tubulin polyglutamylase complex subunit 2
chr19_+_48965304 4.89 ENST00000331825.11
FTL
ferritin light chain
chr18_-_36829154 4.53 ENST00000614939.4
ENST00000610723.4
TPGS2
tubulin polyglutamylase complex subunit 2
chr3_+_184315131 4.39 ENST00000427845.5
ENST00000342981.8
EIF4G1
eukaryotic translation initiation factor 4 gamma 1
chr2_-_110115811 4.27 ENST00000272462.3
MALL
mal, T cell differentiation protein like
chr11_+_20599602 4.19 ENST00000525748.6
SLC6A5
solute carrier family 6 member 5
chr19_+_38930916 3.98 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr9_-_109498251 3.95 ENST00000374541.4
ENST00000262539.7
PTPN3
protein tyrosine phosphatase non-receptor type 3
chr6_-_89352706 3.94 ENST00000435041.3
UBE2J1
ubiquitin conjugating enzyme E2 J1
chr1_-_21783134 3.93 ENST00000308271.14
USP48
ubiquitin specific peptidase 48
chr5_+_127517611 3.47 ENST00000296666.13
ENST00000442138.6
ENST00000512635.2
PRRC1
proline rich coiled-coil 1
chr14_-_22957100 3.45 ENST00000555367.5
HAUS4
HAUS augmin like complex subunit 4
chr11_-_66289007 3.43 ENST00000431556.6
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein
chr19_+_36115439 3.30 ENST00000629269.2
ENST00000221855.8
ENST00000651435.1
ENST00000589996.5
ENST00000591296.1
TBCB
tubulin folding cofactor B
chr19_+_49850687 3.15 ENST00000594151.5
ENST00000600603.5
ENST00000601638.5
PTOV1
PTOV1 extended AT-hook containing adaptor protein
chr18_-_36828771 3.01 ENST00000589049.5
ENST00000587129.5
ENST00000590842.5
TPGS2
tubulin polyglutamylase complex subunit 2
chr22_+_46674593 2.73 ENST00000408031.1
GRAMD4
GRAM domain containing 4
chr20_-_17682234 2.69 ENST00000377813.6
ENST00000377807.6
ENST00000360807.8
ENST00000398782.2
RRBP1
ribosome binding protein 1
chr19_-_54115271 2.40 ENST00000391757.1
TFPT
TCF3 fusion partner
chr6_+_131808011 2.36 ENST00000647893.1
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr10_-_22003678 2.23 ENST00000376980.8
DNAJC1
DnaJ heat shock protein family (Hsp40) member C1
chr14_+_101964561 2.21 ENST00000643508.2
ENST00000680137.1
ENST00000644881.2
ENST00000645149.2
ENST00000681574.1
ENST00000360184.10
ENST00000679720.1
ENST00000645114.2
DYNC1H1
dynein cytoplasmic 1 heavy chain 1
chr19_+_46601296 1.92 ENST00000598871.5
ENST00000291295.14
ENST00000594523.5
CALM3
calmodulin 3
chr12_-_27970047 1.80 ENST00000395868.7
PTHLH
parathyroid hormone like hormone
chr11_-_31803620 1.66 ENST00000639006.1
PAX6
paired box 6
chr6_-_111605859 1.56 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3IP2
TRAF3 interacting protein 2
chr2_-_219543793 1.45 ENST00000243776.11
CHPF
chondroitin polymerizing factor
chr12_-_27970273 1.20 ENST00000542963.1
ENST00000535992.5
PTHLH
parathyroid hormone like hormone
chr10_-_126388455 1.08 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM12
ADAM metallopeptidase domain 12
chr1_-_27914513 1.01 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
RPA2
replication protein A2
chr2_+_64453969 0.74 ENST00000464281.5
LGALSL
galectin like
chr8_+_66712700 0.61 ENST00000521198.7
SGK3
serum/glucocorticoid regulated kinase family member 3
chr6_-_43629222 0.58 ENST00000307126.10
GTPBP2
GTP binding protein 2
chr11_-_31803960 0.56 ENST00000640872.1
ENST00000639109.1
ENST00000638629.1
ENST00000639386.2
PAX6
paired box 6
chrX_+_9463272 0.52 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
TBL1X
transducin beta like 1 X-linked
chr19_-_54115626 0.42 ENST00000391759.6
TFPT
TCF3 fusion partner
chr11_+_61828280 0.40 ENST00000521849.5
ENST00000278840.9
FADS2
fatty acid desaturase 2
chr5_-_9546066 0.37 ENST00000382496.10
ENST00000652226.1
SEMA5A
semaphorin 5A
chr1_-_21783189 0.30 ENST00000400301.5
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr20_-_8019744 0.22 ENST00000246024.7
TMX4
thioredoxin related transmembrane protein 4
chr2_-_15561305 0.05 ENST00000281513.10
NBAS
NBAS subunit of NRZ tethering complex
chr11_-_31803663 0.02 ENST00000638802.1
ENST00000638878.1
PAX6
paired box 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
30.0 90.1 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
23.8 119.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
13.2 119.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
13.1 65.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
10.2 30.7 GO:1903004 flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
9.8 39.1 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
7.8 46.9 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
7.0 28.0 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
7.0 27.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
6.1 18.4 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
5.7 17.1 GO:0000103 sulfate assimilation(GO:0000103)
5.6 94.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
5.2 51.6 GO:0006621 protein retention in ER lumen(GO:0006621)
4.9 14.7 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
4.6 59.9 GO:0019388 galactose catabolic process(GO:0019388)
4.3 68.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
4.1 28.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
4.0 19.9 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
3.7 26.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
3.5 13.9 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
2.8 11.0 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
2.7 18.9 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
2.7 37.8 GO:0043589 skin morphogenesis(GO:0043589)
2.6 17.9 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
2.4 12.1 GO:0019348 dolichol metabolic process(GO:0019348)
2.4 12.0 GO:0006177 GMP biosynthetic process(GO:0006177)
2.4 33.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.2 33.0 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
1.9 17.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
1.9 5.6 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
1.7 5.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
1.7 19.9 GO:0048251 elastic fiber assembly(GO:0048251)
1.6 31.0 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
1.6 10.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.5 13.5 GO:0060613 fat pad development(GO:0060613)
1.4 4.2 GO:0036233 glycine import(GO:0036233)
1.4 45.3 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
1.3 21.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
1.3 26.0 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.3 120.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
1.3 7.6 GO:0048254 snoRNA localization(GO:0048254)
1.1 9.9 GO:0071492 cellular response to UV-A(GO:0071492)
1.1 18.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
1.0 30.0 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.9 13.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.9 13.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.8 20.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.8 27.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.8 14.7 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.7 4.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.7 36.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.7 10.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.6 35.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.5 12.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.5 27.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.5 16.4 GO:0009303 rRNA transcription(GO:0009303)
0.4 19.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.4 2.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.4 3.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) regulation of membrane depolarization during action potential(GO:0098902)
0.4 4.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4 7.0 GO:0045056 transcytosis(GO:0045056)
0.4 21.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3 22.4 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.3 2.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 5.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.3 24.5 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.2 103.3 GO:0043687 post-translational protein modification(GO:0043687)
0.2 6.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.2 29.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 23.5 GO:0007030 Golgi organization(GO:0007030)
0.2 12.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 7.7 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 3.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 1.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 18.4 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.1 15.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.1 1.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 8.5 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.1 3.5 GO:0051225 spindle assembly(GO:0051225)
0.1 14.6 GO:0006457 protein folding(GO:0006457)
0.1 1.0 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 4.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 6.5 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 12.0 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 19.0 GO:0007015 actin filament organization(GO:0007015)
0.0 6.8 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 13.0 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 8.4 GO:0006914 autophagy(GO:0006914)
0.0 0.4 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 10.0 GO:0006974 cellular response to DNA damage stimulus(GO:0006974)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
17.0 119.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
11.7 46.9 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
7.7 30.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
7.6 75.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
7.3 43.9 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
7.1 28.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
5.6 33.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
4.5 26.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
4.2 76.1 GO:0030127 COPII vesicle coat(GO:0030127)
2.9 14.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
2.9 37.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.8 39.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
2.8 33.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
2.7 32.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.6 39.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.6 28.1 GO:0030126 COPI vesicle coat(GO:0030126)
2.3 22.6 GO:0046581 intercellular canaliculus(GO:0046581)
2.1 33.0 GO:0016600 flotillin complex(GO:0016600)
1.9 26.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
1.6 19.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.4 5.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.3 15.4 GO:1990023 mitotic spindle midzone(GO:1990023)
1.2 45.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.2 4.9 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
1.2 38.1 GO:0000421 autophagosome membrane(GO:0000421)
1.1 21.2 GO:0042599 lamellar body(GO:0042599)
1.0 29.6 GO:0042101 T cell receptor complex(GO:0042101)
1.0 17.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.9 7.7 GO:0044194 cytolytic granule(GO:0044194)
0.8 56.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.8 12.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.8 133.9 GO:0032587 ruffle membrane(GO:0032587)
0.7 31.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.7 20.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.7 13.9 GO:0005652 nuclear lamina(GO:0005652)
0.6 46.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.6 191.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.6 46.2 GO:0035580 specific granule lumen(GO:0035580)
0.5 53.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 7.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.5 19.9 GO:0005581 collagen trimer(GO:0005581)
0.4 6.5 GO:0097433 dense body(GO:0097433)
0.4 3.5 GO:0070652 HAUS complex(GO:0070652)
0.2 14.0 GO:0005876 spindle microtubule(GO:0005876)
0.2 13.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 21.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 27.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 16.4 GO:0005901 caveola(GO:0005901)
0.2 28.0 GO:0030496 midbody(GO:0030496)
0.1 2.8 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 48.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 4.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 13.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 6.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 7.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 30.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 99.4 GO:0070062 extracellular exosome(GO:0070062)
0.0 19.1 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)
0.0 27.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.6 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
23.8 119.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
23.7 94.9 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
20.0 59.9 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
11.7 35.0 GO:0005046 KDEL sequence binding(GO:0005046)
8.7 26.0 GO:0004766 spermidine synthase activity(GO:0004766)
7.1 28.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
6.7 20.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
6.6 19.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
6.1 18.4 GO:0031403 lithium ion binding(GO:0031403)
5.6 33.9 GO:0005047 signal recognition particle binding(GO:0005047)
5.1 30.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
4.7 28.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
4.1 16.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
3.5 118.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
3.4 27.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
3.2 32.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
3.0 12.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
3.0 12.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
2.9 46.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
2.9 37.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
2.8 16.6 GO:0046923 ER retention sequence binding(GO:0046923)
2.2 19.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
2.1 12.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
2.0 13.9 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
2.0 52.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.9 7.6 GO:0030622 U4atac snRNA binding(GO:0030622)
1.8 10.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.7 6.9 GO:0008184 glycogen phosphorylase activity(GO:0008184)
1.7 30.5 GO:0070513 death domain binding(GO:0070513)
1.5 7.7 GO:0030348 syntaxin-3 binding(GO:0030348)
1.5 12.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
1.3 27.9 GO:0008242 omega peptidase activity(GO:0008242)
1.1 5.6 GO:0019776 Atg8 ligase activity(GO:0019776)
1.1 19.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
1.1 3.2 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
1.0 4.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.9 17.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.9 17.9 GO:0035497 cAMP response element binding(GO:0035497)
0.9 21.5 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.8 13.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.8 2.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.8 14.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8 41.4 GO:0043022 ribosome binding(GO:0043022)
0.6 12.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.6 14.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.6 9.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.5 14.8 GO:0017166 vinculin binding(GO:0017166)
0.5 1.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.4 13.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 19.0 GO:0003785 actin monomer binding(GO:0003785)
0.4 18.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.4 33.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.4 4.9 GO:0008199 ferric iron binding(GO:0008199)
0.4 4.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 41.3 GO:0051087 chaperone binding(GO:0051087)
0.3 19.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.3 38.6 GO:0008565 protein transporter activity(GO:0008565)
0.3 24.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 57.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 26.8 GO:0008276 protein methyltransferase activity(GO:0008276)
0.2 8.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 22.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 5.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 23.8 GO:0000149 SNARE binding(GO:0000149)
0.2 3.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 2.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 14.0 GO:0008013 beta-catenin binding(GO:0008013)
0.1 84.8 GO:0005509 calcium ion binding(GO:0005509)
0.1 3.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 3.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 3.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 126.6 GO:0003723 RNA binding(GO:0003723)
0.1 19.1 GO:0005525 GTP binding(GO:0005525)
0.0 48.4 GO:0032403 protein complex binding(GO:0032403)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 37.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.8 17.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.8 49.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.7 118.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.6 108.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.6 13.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.6 14.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.6 27.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.4 13.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 5.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 39.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 7.0 PID ARF 3PATHWAY Arf1 pathway
0.2 28.6 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 14.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 5.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 12.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 37.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.2 62.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.1 151.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
1.5 12.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
1.4 90.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
1.3 26.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.0 36.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
1.0 17.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.0 9.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.9 13.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.9 28.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.8 59.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.8 12.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.8 5.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.8 19.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.7 38.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.7 12.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.6 93.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.6 25.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.6 21.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.5 43.6 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.4 14.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.4 30.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.4 59.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.3 6.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 21.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.3 13.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 29.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 16.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 37.0 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 3.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 4.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 5.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 6.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 3.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 4.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 3.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer