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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZBED1

Z-value: 1.27

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Transcription factors associated with ZBED1

Gene Symbol Gene ID Gene Info
ZBED1
ENSG00000214717.12 ZBED1
ZBED1
ENSG00000214717.12 ZBED1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBED1hg38_v1_chrX_-_2500555_25005800.291.9e-05Click!

Activity profile of ZBED1 motif

Sorted Z-values of ZBED1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBED1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_54137740 13.48 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CNOT3
CCR4-NOT transcription complex subunit 3
chr1_+_35557768 5.41 ENST00000356090.8
ENST00000373243.7
NCDN
neurochondrin
chr17_+_4940008 5.40 ENST00000571816.5
ENST00000573404.5
ENST00000576452.5
RNF167
ring finger protein 167
chr17_+_4940259 5.32 ENST00000262482.11
RNF167
ring finger protein 167
chr17_+_4940118 5.12 ENST00000572430.5
RNF167
ring finger protein 167
chr22_+_19714450 4.94 ENST00000455784.7
ENST00000406395.5
SEPTIN5
septin 5
chr17_+_4940384 4.83 ENST00000576229.5
RNF167
ring finger protein 167
chr17_+_4940359 4.76 ENST00000575111.5
RNF167
ring finger protein 167
chr17_-_4940023 4.73 ENST00000225665.12
ENST00000544061.6
SLC25A11
solute carrier family 25 member 11
chr7_+_139341311 3.93 ENST00000297534.7
ENST00000541515.3
FMC1
FMC1-LUC7L2
formation of mitochondrial complex V assembly factor 1 homolog
FMC1-LUC7L2 readthrough
chr9_+_33290493 3.12 ENST00000379540.8
ENST00000318524.6
NFX1
nuclear transcription factor, X-box binding 1
chrX_-_53684119 2.39 ENST00000342160.7
ENST00000446750.1
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
chr17_-_4939911 2.15 ENST00000576951.1
SLC25A11
solute carrier family 25 member 11
chrX_-_64395417 1.43 ENST00000374852.4
MTMR8
myotubularin related protein 8
chr22_-_36028773 1.25 ENST00000438146.7
RBFOX2
RNA binding fox-1 homolog 2
chr2_+_47783082 0.69 ENST00000614496.4
ENST00000622629.4
ENST00000234420.11
ENST00000616033.4
ENST00000673637.1
MSH6
mutS homolog 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.9 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.6 13.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.4 3.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.3 3.9 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 27.8 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 5.4 GO:0045453 bone resorption(GO:0045453)
0.0 1.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 13.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.4 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 27.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 6.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing