avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ZBTB4 Links Ensembl NCBI GeneCards UniProt	ENSG00000174282.12	ZBTB4

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Promoter	Score	Transcript	Gene	Gene Info
chrX_+_103376389 Show fit	35.77	ENST00000372645.3 ENST00000372635.1	BEX3 Links Ensembl NCBI GeneCards UniProt Show fit	brain expressed X-linked 3
chrX_+_103376488 Show fit	35.59	ENST00000361298.9	BEX3 Links Ensembl NCBI GeneCards UniProt Show fit	brain expressed X-linked 3
chr14_-_68979251 Show fit	30.80	ENST00000438964.6 ENST00000679147.1	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr14_-_68979274 Show fit	30.79	ENST00000394419.9	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr14_-_68979314 Show fit	30.52	ENST00000684713.1 ENST00000683198.1 ENST00000684598.1 ENST00000682331.1 ENST00000682291.1 ENST00000683342.1	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr14_-_68979076 Show fit	30.26	ENST00000538545.6 ENST00000684639.1	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr14_-_68979436 Show fit	27.32	ENST00000193403.10	ACTN1 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr12_+_104215772 Show fit	21.44	ENST00000429002.6 ENST00000525566.6	TXNRD1 Links Ensembl NCBI GeneCards UniProt Show fit	thioredoxin reductase 1
chr7_+_157337520 Show fit	20.38	ENST00000412557.5 ENST00000453383.5	DNAJB6 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B6
chr19_-_10420121 Show fit	18.65	ENST00000593124.1	CDC37 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 37, HSP90 cochaperone
chrX_-_69165430 Show fit	16.53	ENST00000374584.3 ENST00000590146.1 ENST00000374571.5	PJA1 Links Ensembl NCBI GeneCards UniProt Show fit	praja ring finger ubiquitin ligase 1
chr3_-_57597443 Show fit	16.44	ENST00000463880.1	ARF4 Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 4
chr11_+_86800527 Show fit	16.05	ENST00000280258.6	PRSS23 Links Ensembl NCBI GeneCards UniProt Show fit	serine protease 23
chrX_-_69165509 Show fit	15.00	ENST00000361478.1	PJA1 Links Ensembl NCBI GeneCards UniProt Show fit	praja ring finger ubiquitin ligase 1
chr19_+_46601296 Show fit	14.31	ENST00000598871.5 ENST00000291295.14 ENST00000594523.5	CALM3 Links Ensembl NCBI GeneCards UniProt Show fit	calmodulin 3
chr15_+_78873030 Show fit	13.69	ENST00000558502.5	MORF4L1 Links Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 1
chr19_+_38647679 Show fit	13.15	ENST00000390009.7 ENST00000589528.1	ACTN4 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 4
chr1_+_166839425 Show fit	11.80	ENST00000449930.5 ENST00000367876.9	POGK Links Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with KRAB domain
chr11_-_125592448 Show fit	11.54	ENST00000648911.1	FEZ1 Links Ensembl NCBI GeneCards UniProt Show fit	fasciculation and elongation protein zeta 1
chr3_-_57597325 Show fit	11.41	ENST00000496292.5 ENST00000489843.1 ENST00000303436.11	ARF4 Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 4
chr1_-_19484635 Show fit	11.31	ENST00000433834.5	CAPZB Links Ensembl NCBI GeneCards UniProt Show fit	capping actin protein of muscle Z-line subunit beta
chr15_+_78872954 Show fit	11.30	ENST00000558746.5 ENST00000558830.5 ENST00000559345.5	MORF4L1 Links Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 1
chr12_-_49131391 Show fit	10.98	ENST00000336023.9 ENST00000550367.1 ENST00000552984.1 ENST00000547476.5	TUBA1B Links Ensembl NCBI GeneCards UniProt Show fit	tubulin alpha 1b
chr5_+_102755269 Show fit	10.86	ENST00000304400.12 ENST00000455264.7 ENST00000684529.1 ENST00000438793.8 ENST00000682882.1 ENST00000682972.1 ENST00000348126.7 ENST00000512073.1	PAM Links Ensembl NCBI GeneCards UniProt Show fit	peptidylglycine alpha-amidating monooxygenase
chr19_+_46601237 Show fit	10.79	ENST00000597743.5	CALM3 Links Ensembl NCBI GeneCards UniProt Show fit	calmodulin 3
chr4_-_7068033 Show fit	10.70	ENST00000264954.5	GRPEL1 Links Ensembl NCBI GeneCards UniProt Show fit	GrpE like 1, mitochondrial
chr10_+_119726041 Show fit	10.51	ENST00000650623.2 ENST00000649251.1	INPP5F Links Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-5-phosphatase F
chr13_-_23433735 Show fit	10.30	ENST00000423156.2 ENST00000683210.1 ENST00000682775.1 ENST00000684497.1 ENST00000682944.1 ENST00000683489.1 ENST00000684385.1 ENST00000683680.1	SACS Links Ensembl NCBI GeneCards UniProt Show fit	sacsin molecular chaperone
chr17_-_15262537 Show fit	10.12	ENST00000395936.7 ENST00000675819.1 ENST00000674707.1 ENST00000675854.1 ENST00000426385.4 ENST00000395938.7 ENST00000612492.5 ENST00000675808.1	PMP22 Links Ensembl NCBI GeneCards UniProt Show fit	peripheral myelin protein 22
chr15_+_42404719 Show fit	9.92	ENST00000569136.6 ENST00000673936.1 ENST00000673890.1 ENST00000674149.1 ENST00000673771.1 ENST00000337571.9 ENST00000673743.1 ENST00000674146.1 ENST00000674119.1 ENST00000356316.7 ENST00000673692.1 ENST00000674052.1	CAPN3 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 3
chr13_-_23433676 Show fit	9.75	ENST00000682547.1 ENST00000455470.6 ENST00000382292.9	SACS Links Ensembl NCBI GeneCards UniProt Show fit	sacsin molecular chaperone
chr15_+_42404820 Show fit	9.55	ENST00000673839.1 ENST00000673978.1	CAPN3 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 3
chr15_+_42404866 Show fit	9.52	ENST00000674041.1 ENST00000565559.5 ENST00000673750.1 ENST00000674135.1	CAPN3 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 3
chr1_-_31937769 Show fit	9.13	ENST00000649841.1 ENST00000534796.5	PTP4A2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A2
chr1_-_36149450 Show fit	9.09	ENST00000373163.5	TRAPPC3 Links Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3
chr2_-_10812706 Show fit	9.07	ENST00000272227.8	PDIA6 Links Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 6
chr15_+_42404793 Show fit	8.98	ENST00000561817.5 ENST00000674018.1 ENST00000397204.9 ENST00000673886.1 ENST00000674139.1 ENST00000673851.1	CAPN3 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 3
chr15_+_42404842 Show fit	8.95	ENST00000673928.1	CAPN3 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 3
chr2_+_63840944 Show fit	8.94	ENST00000484142.2 ENST00000482668.5 ENST00000467648.6 ENST00000394417.7	UGP2 Links Ensembl NCBI GeneCards UniProt Show fit	UDP-glucose pyrophosphorylase 2
chr15_+_42404700 Show fit	8.93	ENST00000674093.1	CAPN3 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 3
chr15_+_78872881 Show fit	8.88	ENST00000559930.5 ENST00000426013.7	MORF4L1 Links Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 1
chr1_-_165768835 Show fit	8.82	ENST00000481278.5	TMCO1 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domains 1
chr13_+_112968496 Show fit	8.17	ENST00000397030.5	MCF2L Links Ensembl NCBI GeneCards UniProt Show fit	MCF.2 cell line derived transforming sequence like
chrX_+_49171889 Show fit	8.04	ENST00000376327.6	PLP2 Links Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 2
chr11_+_65919261 Show fit	8.03	ENST00000525501.5	DRAP1 Links Ensembl NCBI GeneCards UniProt Show fit	DR1 associated protein 1
chrX_-_110318062 Show fit	7.92	ENST00000372059.6 ENST00000262844.10	AMMECR1 Links Ensembl NCBI GeneCards UniProt Show fit	AMMECR nuclear protein 1
chr17_+_74987581 Show fit	7.92	ENST00000337231.5	CDR2L Links Ensembl NCBI GeneCards UniProt Show fit	cerebellar degeneration related protein 2 like
chr2_-_10812794 Show fit	7.91	ENST00000540494.5	PDIA6 Links Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 6
chr8_-_27611325 Show fit	7.88	ENST00000523500.5	CLU Links Ensembl NCBI GeneCards UniProt Show fit	clusterin
chrX_+_49171918 Show fit	7.76	ENST00000376322.7	PLP2 Links Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 2
chr1_+_154974672 Show fit	7.71	ENST00000308987.6 ENST00000368436.1	CKS1B Links Ensembl NCBI GeneCards UniProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr17_-_81869934 Show fit	7.67	ENST00000580685.5	ARHGDIA Links Ensembl NCBI GeneCards UniProt Show fit	Rho GDP dissociation inhibitor alpha
chr1_-_67430320 Show fit	7.66	ENST00000370990.5	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr2_-_36598140 Show fit	7.65	ENST00000405912.8 ENST00000379245.8	FEZ2 Links Ensembl NCBI GeneCards UniProt Show fit	fasciculation and elongation protein zeta 2
chr1_-_36149464 Show fit	7.58	ENST00000373166.8 ENST00000373159.1 ENST00000373162.5 ENST00000616074.4 ENST00000616395.4	TRAPPC3 Links Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3
chr19_+_38647614 Show fit	7.52	ENST00000252699.7 ENST00000424234.7 ENST00000440400.2	ACTN4 Links Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 4
chr3_-_167734832 Show fit	7.44	ENST00000464360.5 ENST00000492139.5 ENST00000471885.5 ENST00000392750.7 ENST00000470131.5	PDCD10 Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 10
chr14_-_23352741 Show fit	7.39	ENST00000354772.9	SLC22A17 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 17
chr14_-_23352872 Show fit	7.38	ENST00000397267.5	SLC22A17 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 17
chr6_-_49463173 Show fit	7.23	ENST00000274813.4	MMUT Links Ensembl NCBI GeneCards UniProt Show fit	methylmalonyl-CoA mutase
chr1_+_154974653 Show fit	7.18	ENST00000368439.5	CKS1B Links Ensembl NCBI GeneCards UniProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr10_+_103277129 Show fit	6.98	ENST00000369849.9	INA Links Ensembl NCBI GeneCards UniProt Show fit	internexin neuronal intermediate filament protein alpha
chr1_-_67430412 Show fit	6.87	ENST00000370994.8	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr7_-_44573895 Show fit	6.84	ENST00000258772.10 ENST00000431640.5	DDX56 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 56
chr19_+_52220983 Show fit	6.77	ENST00000391791.4	PPP2R1A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 scaffold subunit Aalpha
chr9_-_86282511 Show fit	6.52	ENST00000375991.9 ENST00000326094.4	ISCA1 Links Ensembl NCBI GeneCards UniProt Show fit	iron-sulfur cluster assembly 1
chr17_-_43778937 Show fit	6.51	ENST00000226004.8	DUSP3 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 3
chr1_-_67430386 Show fit	6.43	ENST00000370995.6 ENST00000361219.11	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr7_+_157336961 Show fit	6.39	ENST00000429029.6	DNAJB6 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B6
chr22_+_19941862 Show fit	6.30	ENST00000428707.2	COMT Links Ensembl NCBI GeneCards UniProt Show fit	catechol-O-methyltransferase
chr17_-_9575811 Show fit	6.26	ENST00000306357.9 ENST00000574431.5	STX8 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 8
chr6_-_13711817 Show fit	6.21	ENST00000011619.6	RANBP9 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 9
chr15_+_24954912 Show fit	5.97	ENST00000584968.5 ENST00000346403.10 ENST00000554227.6 ENST00000390687.9 ENST00000579070.5 ENST00000577565.1 ENST00000577949.5 ENST00000338327.4	SNRPN Links Ensembl NCBI GeneCards UniProt Show fit SNURF Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide N SNRPN upstream reading frame
chr15_-_68820861 Show fit	5.74	ENST00000560303.1 ENST00000465139.6	ANP32A Links Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member A
chr17_+_7583828 Show fit	5.56	ENST00000396501.8 ENST00000250124.11 ENST00000584378.5 ENST00000423172.6 ENST00000579445.5 ENST00000585217.5 ENST00000581380.1	MPDU1 Links Ensembl NCBI GeneCards UniProt Show fit	mannose-P-dolichol utilization defect 1
chr19_+_1103926 Show fit	5.56	ENST00000616066.4 ENST00000354171.13 ENST00000589115.6 ENST00000611653.4 ENST00000593032.5 ENST00000588919.5	GPX4 Links Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 4
chr8_-_73293616 Show fit	5.50	ENST00000352983.7 ENST00000396467.5	RPL7 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L7
chr14_-_24232332 Show fit	5.36	ENST00000534348.5 ENST00000524927.1 ENST00000250495.10	NEDD8-MDP1 Links Ensembl NCBI GeneCards UniProt Show fit NEDD8 Links Ensembl NCBI GeneCards UniProt Show fit	NEDD8-MDP1 readthrough NEDD8 ubiquitin like modifier
chr6_+_49463360 Show fit	5.06	ENST00000335783.4	CENPQ Links Ensembl NCBI GeneCards UniProt Show fit	centromere protein Q
chr9_-_86282061 Show fit	4.91	ENST00000311534.6	ISCA1 Links Ensembl NCBI GeneCards UniProt Show fit	iron-sulfur cluster assembly 1
chr8_-_70669142 Show fit	4.84	ENST00000522447.5 ENST00000276590.5	LACTB2 Links Ensembl NCBI GeneCards UniProt Show fit	lactamase beta 2
chr10_-_32056376 Show fit	4.81	ENST00000302418.5	KIF5B Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 5B
chr22_+_49918733 Show fit	4.74	ENST00000407217.7 ENST00000403427.3	CRELD2 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine rich with EGF like domains 2
chr3_+_51977833 Show fit	4.71	ENST00000637978.1	ABHD14A-ACY1 Links Ensembl NCBI GeneCards UniProt Show fit	ABHD14A-ACY1 readthrough
chr16_-_30526758 Show fit	4.71	ENST00000562803.1	ZNF768 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 768
chr8_-_29350666 Show fit	4.64	ENST00000240100.7	DUSP4 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 4
chr19_-_41397256 Show fit	4.63	ENST00000602129.1 ENST00000593771.1 ENST00000596905.1 ENST00000221233.9	EXOSC5 Links Ensembl NCBI GeneCards UniProt Show fit	exosome component 5
chr14_-_25010604 Show fit	4.63	ENST00000550887.5	STXBP6 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 6
chr1_-_165768848 Show fit	4.53	ENST00000367881.11 ENST00000464650.5 ENST00000612311.4 ENST00000628579.1	TMCO1 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domains 1
chr7_+_103297425 Show fit	4.44	ENST00000428154.5 ENST00000249269.9	PMPCB Links Ensembl NCBI GeneCards UniProt Show fit	peptidase, mitochondrial processing subunit beta
chr11_-_72674394 Show fit	4.39	ENST00000418754.6 ENST00000334456.10 ENST00000542969.2	PDE2A Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr6_-_136526472 Show fit	4.29	ENST00000454590.5 ENST00000432797.6	MAP7 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 7
chr19_-_17245889 Show fit	4.25	ENST00000291442.4	NR2F6 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 6
chr17_-_81512671 Show fit	4.18	ENST00000679480.1 ENST00000644774.2 ENST00000571721.6 ENST00000575842.5 ENST00000575087.5 ENST00000573283.7 ENST00000571691.6 ENST00000570382.2	ACTG1 Links Ensembl NCBI GeneCards UniProt Show fit	actin gamma 1
chr19_+_35143237 Show fit	4.14	ENST00000586063.5 ENST00000270310.7 ENST00000588265.1	FXYD7 Links Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 7
chr2_-_1744442 Show fit	4.13	ENST00000433670.5 ENST00000425171.1 ENST00000252804.9	PXDN Links Ensembl NCBI GeneCards UniProt Show fit	peroxidasin
chr8_-_27611424 Show fit	4.10	ENST00000405140.7	CLU Links Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr14_+_24232892 Show fit	4.09	ENST00000420554.6	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr16_+_1989949 Show fit	4.04	ENST00000248121.7 ENST00000618464.1	SYNGR3 Links Ensembl NCBI GeneCards UniProt Show fit	synaptogyrin 3
chr8_+_11802611 Show fit	3.99	ENST00000623368.3	FDFT1 Links Ensembl NCBI GeneCards UniProt Show fit	farnesyl-diphosphate farnesyltransferase 1
chr22_+_49918626 Show fit	3.98	ENST00000328268.9 ENST00000404488.7	CRELD2 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine rich with EGF like domains 2
chr1_-_154974361 Show fit	3.83	ENST00000368453.8 ENST00000368450.5	SHC1 Links Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 1
chr19_-_39391029 Show fit	3.76	ENST00000221265.8	PAF1 Links Ensembl NCBI GeneCards UniProt Show fit	PAF1 homolog, Paf1/RNA polymerase II complex component
chr1_+_10474936 Show fit	3.71	ENST00000356607.9 ENST00000491661.2	PEX14 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 14
chr14_-_34630124 Show fit	3.52	ENST00000362031.10 ENST00000557265.6 ENST00000652385.1	SNX6 Links Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 6
chr21_-_37072688 Show fit	3.41	ENST00000464265.5 ENST00000399102.5	PIGP Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class P
chr15_-_43824675 Show fit	3.39	ENST00000267812.4	MFAP1 Links Ensembl NCBI GeneCards UniProt Show fit	microfibril associated protein 1
chrX_-_153470555 Show fit	3.36	ENST00000370211.10 ENST00000330912.7 ENST00000334497.7 ENST00000338525.7 ENST00000370232.4	HAUS7 Links Ensembl NCBI GeneCards UniProt Show fit TREX2 Links Ensembl NCBI GeneCards UniProt Show fit	HAUS augmin like complex subunit 7 three prime repair exonuclease 2
chr10_+_103245887 Show fit	3.35	ENST00000441178.2	RPEL1 Links Ensembl NCBI GeneCards UniProt Show fit	ribulose-5-phosphate-3-epimerase like 1
chr19_+_38930916 Show fit	3.32	ENST00000308018.9 ENST00000407800.2 ENST00000402029.3	MRPS12 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S12
chr19_-_39391137 Show fit	3.30	ENST00000595564.5	PAF1 Links Ensembl NCBI GeneCards UniProt Show fit	PAF1 homolog, Paf1/RNA polymerase II complex component
chr3_+_148865288 Show fit	3.30	ENST00000296046.4	CPA3 Links Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A3
chr7_+_157336988 Show fit	3.26	ENST00000262177.9 ENST00000417758.5 ENST00000443280.5	DNAJB6 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B6
chr14_+_24232612 Show fit	3.25	ENST00000560139.5 ENST00000559910.5 ENST00000348719.11	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr2_+_231786383 Show fit	3.23	ENST00000620578.4 ENST00000412591.5 ENST00000410017.5 ENST00000350033.8 ENST00000373608.7	COPS7B Links Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 7B
chr20_-_38165261 Show fit	3.07	ENST00000361475.7	TGM2 Links Ensembl NCBI GeneCards UniProt Show fit	transglutaminase 2
chr8_+_93916882 Show fit	3.04	ENST00000297598.5 ENST00000520728.5 ENST00000518107.5 ENST00000396200.3	PDP1 Links Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr4_+_70688511 Show fit	2.92	ENST00000254803.4	UTP3 Links Ensembl NCBI GeneCards UniProt Show fit	UTP3 small subunit processome component
chr11_-_31805795 Show fit	2.82	ENST00000640766.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr14_+_24232422 Show fit	2.77	ENST00000620807.4 ENST00000355299.8 ENST00000559836.5	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr3_+_49470240 Show fit	2.70	ENST00000431960.5 ENST00000308775.7 ENST00000452317.5 ENST00000435508.7 ENST00000452060.6 ENST00000673708.1 ENST00000428779.6 ENST00000430636.1	DAG1 Links Ensembl NCBI GeneCards UniProt Show fit	dystroglycan 1
chr18_-_36067524 Show fit	2.65	ENST00000590898.5 ENST00000357384.8 ENST00000399022.9 ENST00000588737.5	RPRD1A Links Ensembl NCBI GeneCards UniProt Show fit	regulation of nuclear pre-mRNA domain containing 1A
chr1_+_65420578 Show fit	2.50	ENST00000475108.5	LEPROT Links Ensembl NCBI GeneCards UniProt Show fit	leptin receptor overlapping transcript
chr14_+_85530127 Show fit	2.46	ENST00000330753.6	FLRT2 Links Ensembl NCBI GeneCards UniProt Show fit	fibronectin leucine rich transmembrane protein 2
chr11_+_62337424 Show fit	2.38	ENST00000415229.6 ENST00000301776.9 ENST00000628829.2 ENST00000534571.5 ENST00000526096.2	ASRGL1 Links Ensembl NCBI GeneCards UniProt Show fit	asparaginase and isoaspartyl peptidase 1
chr20_+_58840692 Show fit	2.32	ENST00000306090.12	GNAS Links Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr12_-_46372763 Show fit	2.24	ENST00000256689.10	SLC38A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38 member 2
chr4_-_82373946 Show fit	2.20	ENST00000352301.8 ENST00000509107.1 ENST00000353341.8 ENST00000313899.12	HNRNPD Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein D
chrX_+_100820359 Show fit	2.19	ENST00000415585.6 ENST00000372972.7 ENST00000413437.1	CSTF2 Links Ensembl NCBI GeneCards UniProt Show fit	cleavage stimulation factor subunit 2
chr11_-_73761051 Show fit	2.06	ENST00000336083.8 ENST00000536566.5 ENST00000541588.5 ENST00000540771.5 ENST00000310653.10	RAB6A Links Ensembl NCBI GeneCards UniProt Show fit	RAB6A, member RAS oncogene family
chr3_+_19947074 Show fit	2.05	ENST00000273047.9	RAB5A Links Ensembl NCBI GeneCards UniProt Show fit	RAB5A, member RAS oncogene family
chr19_+_35533436 Show fit	1.87	ENST00000222286.9	GAPDHS Links Ensembl NCBI GeneCards UniProt Show fit	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr18_-_49813512 Show fit	1.82	ENST00000285093.15	ACAA2 Links Ensembl NCBI GeneCards UniProt Show fit	acetyl-CoA acyltransferase 2
chr19_-_15332507 Show fit	1.77	ENST00000679869.1 ENST00000360016.9	BRD4 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 4
chr19_+_10106688 Show fit	1.64	ENST00000430370.1	PPAN Links Ensembl NCBI GeneCards UniProt Show fit	peter pan homolog
chr16_+_89490917 Show fit	1.42	ENST00000647079.1	SPG7 Links Ensembl NCBI GeneCards UniProt Show fit	SPG7 matrix AAA peptidase subunit, paraplegin
chr16_-_11276473 Show fit	1.41	ENST00000241808.9 ENST00000435245.2	PRM2 Links Ensembl NCBI GeneCards UniProt Show fit	protamine 2
chr19_+_17511606 Show fit	1.35	ENST00000252603.7 ENST00000600923.5	PGLS Links Ensembl NCBI GeneCards UniProt Show fit	6-phosphogluconolactonase
chr3_-_120094436 Show fit	1.34	ENST00000264235.13 ENST00000677034.1	GSK3B Links Ensembl NCBI GeneCards UniProt Show fit	glycogen synthase kinase 3 beta
chr9_+_130693756 Show fit	1.34	ENST00000546165.5 ENST00000372352.7 ENST00000372358.10 ENST00000372351.7 ENST00000372350.7 ENST00000495699.2	EXOSC2 Links Ensembl NCBI GeneCards UniProt Show fit	exosome component 2
chr14_-_50668287 Show fit	1.33	ENST00000556735.1 ENST00000324679.5	SAV1 Links Ensembl NCBI GeneCards UniProt Show fit	salvador family WW domain containing protein 1
chr3_-_194486945 Show fit	1.19	ENST00000645538.1 ENST00000645319.2	ATP13A3 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase 13A3
chr21_+_33266350 Show fit	1.10	ENST00000290200.7	IL10RB Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 10 receptor subunit beta
chr19_+_9250930 Show fit	1.08	ENST00000456448.3	OR7E24 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 7 subfamily E member 24
chr14_+_22836574 Show fit	1.05	ENST00000548162.2 ENST00000311852.11	MMP14 Links Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 14
chr19_+_54102838 Show fit	1.02	ENST00000391762.5 ENST00000471292.5 ENST00000485876.6 ENST00000391763.3 ENST00000391764.7 ENST00000303553.5	NDUFA3 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit A3
chr17_-_50767505 Show fit	0.99	ENST00000450727.6	ANKRD40CL Links Ensembl NCBI GeneCards UniProt Show fit	ANKRD40 C-terminal like
chr16_-_2340703 Show fit	0.91	ENST00000301732.10 ENST00000382381.7	ABCA3 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 3
chr13_+_24160740 Show fit	0.88	ENST00000382095.8	SPATA13 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 13
chr6_-_82247697 Show fit	0.83	ENST00000306270.12 ENST00000610980.4	IBTK Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of Bruton tyrosine kinase
chr10_+_35195843 Show fit	0.82	ENST00000488741.5 ENST00000474931.5 ENST00000468236.5 ENST00000344351.5 ENST00000490511.1	CREM Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr4_-_155376797 Show fit	0.79	ENST00000650955.1 ENST00000515654.5	MAP9 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 9
chr11_+_121102666 Show fit	0.72	ENST00000264037.2	TECTA Links Ensembl NCBI GeneCards UniProt Show fit	tectorin alpha
chr4_-_155376876 Show fit	0.69	ENST00000433024.5 ENST00000379248.6	MAP9 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 9
chr19_-_3062464 Show fit	0.57	ENST00000327141.9	TLE5 Links Ensembl NCBI GeneCards UniProt Show fit	TLE family member 5, transcriptional modulator
chr10_+_119726118 Show fit	0.56	ENST00000369081.3 ENST00000648262.1	INPP5F Links Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-5-phosphatase F
chr9_+_2017383 Show fit	0.55	ENST00000382194.6	SMARCA2 Links Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_151409878 Show fit	0.41	ENST00000453091.6 ENST00000428287.6 ENST00000444746.7 ENST00000243326.9 ENST00000414861.6	RIF1 Links Ensembl NCBI GeneCards UniProt Show fit	replication timing regulatory factor 1
chr17_-_5486157 Show fit	0.41	ENST00000572834.5 ENST00000158771.9 ENST00000570848.5 ENST00000571971.1	DERL2 Links Ensembl NCBI GeneCards UniProt Show fit	derlin 2
chr3_+_19947316 Show fit	0.37	ENST00000422242.1	RAB5A Links Ensembl NCBI GeneCards UniProt Show fit	RAB5A, member RAS oncogene family
chr19_-_52008081 Show fit	0.27	ENST00000602063.5 ENST00000597747.5 ENST00000594083.5 ENST00000593650.5 ENST00000599631.5 ENST00000598071.6 ENST00000601178.5 ENST00000376716.9 ENST00000391795.7	ZNF615 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 615
chr19_-_15331890 Show fit	0.25	ENST00000594841.5 ENST00000601941.1	BRD4 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 4
chr9_-_108934060 Show fit	0.25	ENST00000675406.1 ENST00000676237.1 ENST00000675825.1 ENST00000675052.1 ENST00000674535.1 ENST00000674938.1 ENST00000374647.10	ELP1 Links Ensembl NCBI GeneCards UniProt Show fit	elongator acetyltransferase complex subunit 1
chr15_+_66293217 Show fit	0.01	ENST00000319194.9 ENST00000525134.6	DIS3L Links Ensembl NCBI GeneCards UniProt Show fit	DIS3 like exosome 3'-5' exoribonuclease

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.5	149.7	GO:0051639	actin filament network formation(GO:0051639)
6.2	55.8	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
3.8	30.0	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
3.4	20.7	GO:0048549	positive regulation of pinocytosis(GO:0048549)
3.1	27.9	GO:0031584	activation of phospholipase D activity(GO:0031584)
3.0	14.8	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.8	11.1	GO:0031161	phosphatidylinositol catabolic process(GO:0031161)
2.7	10.9	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
2.7	21.4	GO:0001887	selenium compound metabolic process(GO:0001887)
2.4	12.0	GO:1902998	regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.3	6.8	GO:1903538	meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
2.1	19.2	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
1.9	11.4	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.6	11.3	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
1.5	8.9	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
1.5	7.4	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.3	20.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
1.3	33.9	GO:0043968	histone H2A acetylation(GO:0043968)
1.2	6.0	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
1.1	4.4	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
1.0	6.2	GO:0016036	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
1.0	2.0	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
1.0	7.1	GO:0016584	nucleosome positioning(GO:0016584)
1.0	14.7	GO:0006983	ER overload response(GO:0006983)
0.9	2.7	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340) regulation of embryonic cell shape(GO:0016476)
0.8	2.5	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.8	18.7	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.8	4.8	GO:0035617	stress granule disassembly(GO:0035617)
0.8	3.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.8	10.7	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.7	3.7	GO:1901094	regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.7	2.2	GO:1901355	response to rapamycin(GO:1901355)
0.7	3.3	GO:0019323	pentose catabolic process(GO:0019323)
0.7	4.0	GO:0008204	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.7	2.6	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.6	7.0	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.6	5.5	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.5	71.4	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.5	2.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.5	7.7	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.5	10.1	GO:0032060	bleb assembly(GO:0032060)
0.5	4.6	GO:0051601	exocyst localization(GO:0051601)
0.4	3.5	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.4	2.4	GO:0051036	regulation of endosome size(GO:0051036)
0.4	10.1	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.3	14.9	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.3	5.4	GO:0045116	protein neddylation(GO:0045116)
0.3	17.0	GO:0043277	apoptotic cell clearance(GO:0043277)
0.3	2.2	GO:0032328	alanine transport(GO:0032328)
0.3	4.4	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3	2.4	GO:0006528	asparagine metabolic process(GO:0006528)
0.3	1.1	GO:1990834	response to odorant(GO:1990834)
0.2	5.0	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2	9.6	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.2	6.5	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2	3.2	GO:0000338	protein deneddylation(GO:0000338)
0.2	10.8	GO:0043486	histone exchange(GO:0043486)
0.2	7.7	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.2	1.9	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.2	16.7	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2	6.2	GO:0007020	microtubule nucleation(GO:0007020)
0.2	4.3	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.2	5.6	GO:0019372	lipoxygenase pathway(GO:0019372)
0.2	3.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.2	6.3	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.2	2.2	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2	1.3	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.2	2.8	GO:0003322	pancreatic A cell development(GO:0003322)
0.2	4.1	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.1	2.3	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.1	0.6	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	3.3	GO:0002003	angiotensin maturation(GO:0002003)
0.1	6.8	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.1	3.8	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1	2.9	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.4	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1	21.0	GO:0043488	regulation of mRNA stability(GO:0043488)
0.1	4.8	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	8.9	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	1.3	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1	1.9	GO:0045821	positive regulation of glycolytic process(GO:0045821)
0.1	4.2	GO:0045214	sarcomere organization(GO:0045214)
0.1	4.0	GO:0021762	substantia nigra development(GO:0021762)
0.1	0.8	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1	1.4	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.1	4.1	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1	0.4	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	8.8	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	3.3	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	3.4	GO:0051225	spindle assembly(GO:0051225)
0.0	26.8	GO:0030163	protein catabolic process(GO:0030163)
0.0	8.6	GO:0043687	post-translational protein modification(GO:0043687)
0.0	1.0	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	2.0	GO:0007286	spermatid development(GO:0007286)
0.0	1.1	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	149.7	GO:0005916	fascia adherens(GO:0005916)
2.7	10.7	GO:0001405	presequence translocase-associated import motor(GO:0001405)
2.1	2.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
2.0	10.1	GO:1902560	GMP reductase complex(GO:1902560)
2.0	20.1	GO:0070852	cell body fiber(GO:0070852)
1.7	33.9	GO:0016580	Sin3 complex(GO:0016580)
1.4	16.7	GO:0030008	TRAPP complex(GO:0030008)
1.1	17.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
1.0	3.8	GO:0070435	Shc-EGFR complex(GO:0070435)
0.9	11.3	GO:0071203	F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203)
0.9	20.7	GO:0031143	pseudopodium(GO:0031143)
0.8	12.0	GO:0097418	neurofibrillary tangle(GO:0097418)
0.6	7.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.6	3.5	GO:0097422	tubular endosome(GO:0097422)
0.5	2.2	GO:0071920	cleavage body(GO:0071920)
0.5	7.0	GO:0005883	neurofilament(GO:0005883)
0.5	55.8	GO:0030315	T-tubule(GO:0030315)
0.5	1.4	GO:0005745	m-AAA complex(GO:0005745)
0.5	6.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.4	6.0	GO:0005687	U4 snRNP(GO:0005687)
0.4	3.4	GO:0070652	HAUS complex(GO:0070652)
0.3	4.8	GO:0035253	ciliary rootlet(GO:0035253)
0.3	4.4	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3	3.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3	2.4	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.3	10.1	GO:0043218	compact myelin(GO:0043218)
0.3	4.2	GO:0097433	dense body(GO:0097433)
0.3	4.6	GO:0000145	exocyst(GO:0000145)
0.3	14.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.3	2.7	GO:0016011	dystroglycan complex(GO:0016011)
0.2	1.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	30.0	GO:0030018	Z disc(GO:0030018)
0.2	4.7	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2	6.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.2	32.2	GO:0043197	dendritic spine(GO:0043197)
0.2	3.4	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	12.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	23.4	GO:0000922	spindle pole(GO:0000922)
0.1	1.3	GO:1990909	Wnt signalosome(GO:1990909)
0.1	20.4	GO:0001650	fibrillar center(GO:0001650)
0.1	3.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	11.1	GO:0005905	clathrin-coated pit(GO:0005905)
0.1	6.5	GO:0001772	immunological synapse(GO:0001772)
0.1	0.9	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	2.9	GO:0032040	small-subunit processome(GO:0032040)
0.1	4.5	GO:0031201	SNARE complex(GO:0031201)
0.1	1.4	GO:0000786	nucleosome(GO:0000786)
0.1	25.2	GO:0031301	integral component of organelle membrane(GO:0031301)
0.1	3.2	GO:0008180	COP9 signalosome(GO:0008180)
0.1	0.4	GO:0001940	female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.1	4.0	GO:0031594	neuromuscular junction(GO:0031594)
0.1	5.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.6	GO:0005875	microtubule associated complex(GO:0005875)
0.0	14.5	GO:0005874	microtubule(GO:0005874)
0.0	7.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	10.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	2.2	GO:0042383	sarcolemma(GO:0042383)
0.0	2.6	GO:0042734	presynaptic membrane(GO:0042734)
0.0	75.0	GO:0070062	extracellular exosome(GO:0070062)
0.0	1.8	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0	1.0	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.5	GO:0016514	SWI/SNF complex(GO:0016514)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.8	71.4	GO:0005163	nerve growth factor receptor binding(GO:0005163)
5.4	152.4	GO:0017166	vinculin binding(GO:0017166)
3.3	55.8	GO:0031432	titin binding(GO:0031432)
2.7	10.9	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.5	14.9	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.2	8.9	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
2.0	10.1	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
1.7	18.6	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
1.5	4.6	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
1.4	11.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.2	4.8	GO:0099609	microtubule lateral binding(GO:0099609)
1.1	3.3	GO:0004750	ribulose-phosphate 3-epimerase activity(GO:0004750)
1.1	5.6	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.0	9.1	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
1.0	7.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.9	17.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.9	30.0	GO:0001671	ATPase activator activity(GO:0001671)
0.8	4.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.8	10.7	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.8	27.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.8	4.7	GO:0004046	aminoacylase activity(GO:0004046)
0.8	3.0	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.7	20.1	GO:0070628	proteasome binding(GO:0070628)
0.7	6.2	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.7	4.0	GO:0004310	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.6	3.8	GO:0048408	epidermal growth factor binding(GO:0048408)
0.6	11.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.6	12.0	GO:0051787	misfolded protein binding(GO:0051787)
0.6	2.4	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.6	3.4	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.5	6.3	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.5	6.5	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.4	4.4	GO:0030911	TPR domain binding(GO:0030911)
0.4	3.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4	20.7	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.4	3.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4	1.9	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4	15.8	GO:0019956	chemokine binding(GO:0019956)
0.4	18.7	GO:0051879	Hsp90 protein binding(GO:0051879)
0.3	11.5	GO:0043015	gamma-tubulin binding(GO:0043015)
0.3	16.7	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3	4.3	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.3	9.1	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.3	3.5	GO:0034452	dynactin binding(GO:0034452)
0.2	43.6	GO:0047485	protein N-terminus binding(GO:0047485)
0.2	4.6	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	1.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.2	23.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.2	6.0	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.1	0.6	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.1	22.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	6.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	28.5	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.1	3.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	1.4	GO:0046870	cadmium ion binding(GO:0046870)
0.1	2.3	GO:0051429	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1	6.8	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	2.1	GO:0031489	myosin V binding(GO:0031489)
0.1	4.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	1.9	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.8	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	6.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	4.8	GO:0004521	endoribonuclease activity(GO:0004521)
0.1	8.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	17.0	GO:0008514	organic anion transmembrane transporter activity(GO:0008514)
0.1	17.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	5.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	7.8	GO:0005262	calcium channel activity(GO:0005262)
0.1	1.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	2.8	GO:0070412	R-SMAD binding(GO:0070412)
0.0	1.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	8.8	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	5.1	GO:0042393	histone binding(GO:0042393)
0.0	7.6	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	1.0	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	5.4	GO:0016791	phosphatase activity(GO:0016791)
0.0	1.1	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.9	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	149.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.5	20.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.3	3.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2	20.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.2	16.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.2	2.7	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.2	13.9	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	36.4	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.2	10.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.2	5.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	20.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.2	4.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	6.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	4.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	3.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	12.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	4.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	13.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	7.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	2.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	6.0	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	2.8	PID CDC42 PATHWAY	CDC42 signaling events
0.1	3.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	1.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.8	PID BCR 5PATHWAY	BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.5	149.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.2	25.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.9	17.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.7	20.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.7	22.5	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.6	21.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5	6.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.4	10.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.4	11.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.4	8.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	14.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.3	15.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.2	6.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2	8.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	17.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	4.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	5.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2	3.0	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	3.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	31.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	7.9	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	2.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	4.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	4.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	12.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	6.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	2.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	2.3	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	2.8	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	4.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.9	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	7.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	6.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	5.5	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	1.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	2.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport