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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZBTB6

Z-value: 7.92

Motif logo

Transcription factors associated with ZBTB6

Gene Symbol Gene ID Gene Info
ENSG00000186130.5 ZBTB6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB6hg38_v1_chr9_-_122913299_1229133330.144.5e-02Click!

Activity profile of ZBTB6 motif

Sorted Z-values of ZBTB6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_204411804 40.70 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr3_-_133895577 21.94 ENST00000543906.5
RAB6B, member RAS oncogene family
chr19_-_42242526 21.18 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr12_-_52520371 21.15 ENST00000549420.1
ENST00000252242.9
ENST00000551275.1
ENST00000546577.1
keratin 5
chr12_-_52493250 18.92 ENST00000330722.7
keratin 6A
chr17_+_28357638 18.65 ENST00000292114.8
ENST00000591482.1
transmembrane protein 199
novel transcript readthrough between TMEM199 and SARM1
chr13_+_26557659 17.40 ENST00000335327.6
ENST00000361042.8
ENST00000671038.1
WASP family member 3
chrX_+_49879475 17.34 ENST00000621775.2
ubiquitin specific peptidase 27 X-linked
chr1_-_11805949 15.61 ENST00000376590.9
methylenetetrahydrofolate reductase
chr1_-_11805977 15.43 ENST00000376486.3
methylenetetrahydrofolate reductase
chr3_-_133895867 15.24 ENST00000285208.9
RAB6B, member RAS oncogene family
chr1_-_11805924 15.17 ENST00000418034.1
methylenetetrahydrofolate reductase
chr15_+_64460728 14.27 ENST00000416172.1
zinc finger protein 609
chr21_+_46458846 13.97 ENST00000417564.3
ENST00000651436.1
ENST00000400274.5
ENST00000457905.7
ENST00000466639.5
ENST00000435722.7
disco interacting protein 2 homolog A
chr19_+_42313374 13.83 ENST00000598766.1
ENST00000673187.1
transmembrane protein 145
chr3_-_58577648 13.70 ENST00000394481.5
family with sequence similarity 107 member A
chr6_+_41072939 13.60 ENST00000341376.11
ENST00000353205.5
nuclear transcription factor Y subunit alpha
chr3_-_133895753 13.55 ENST00000460865.3
RAB6B, member RAS oncogene family
chr10_+_104269163 12.87 ENST00000338595.7
glutathione S-transferase omega 2
chr9_+_34958254 12.61 ENST00000242315.3
PHD finger protein 24
chr14_-_59870752 12.40 ENST00000611068.1
ENST00000267484.10
reticulon 1
chr6_+_42564060 12.28 ENST00000372903.6
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_145095528 12.25 ENST00000612199.4
ENST00000641863.1
SLIT-ROBO Rho GTPase activating protein 2B
chr6_-_33200614 12.17 ENST00000374685.8
ENST00000374680.4
retinoid X receptor beta
chr2_+_110732584 12.08 ENST00000340561.8
acyl-CoA oxidase like
chr1_+_151070740 11.88 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr1_-_182953132 11.80 ENST00000367547.8
SHC binding and spindle associated 1 like
chr21_+_34375500 11.54 ENST00000399299.5
ENST00000399292.8
ENST00000474455.1
ENST00000399295.2
small integral membrane protein 11A
chr6_+_150683593 11.47 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr16_+_4734519 11.28 ENST00000299320.10
chromosome 16 open reading frame 71
chr5_+_170861990 11.26 ENST00000523189.6
RAN binding protein 17
chr1_+_121184964 11.13 ENST00000367123.8
SLIT-ROBO Rho GTPase activating protein 2C
chr11_+_68460712 11.12 ENST00000528635.5
ENST00000533127.5
ENST00000529907.5
ENST00000529344.5
ENST00000534534.5
ENST00000524845.5
ENST00000393800.7
ENST00000265637.8
ENST00000524904.5
ENST00000393801.7
ENST00000265636.9
ENST00000529710.5
protein phosphatase 6 regulatory subunit 3
chr16_+_56191476 11.03 ENST00000262493.12
G protein subunit alpha o1
chr6_+_42879610 11.02 ENST00000493763.7
ENST00000304734.9
ribosomal protein L7 like 1
chr2_+_219627394 10.90 ENST00000373760.6
solute carrier family 4 member 3
chr19_-_57814878 10.86 ENST00000391701.1
zinc finger protein 552
chr10_-_47484133 10.76 ENST00000583911.5
ENST00000611843.4
annexin A8
chr5_-_132556809 10.63 ENST00000450655.1
interleukin 5
chr7_+_139231225 10.56 ENST00000473989.8
ubinuclein 2
chr22_-_20117177 10.37 ENST00000439169.2
ENST00000252136.12
ENST00000445045.1
ENST00000404751.7
ENST00000403707.7
tRNA methyltransferase 2 homolog A
chr11_+_117199363 10.34 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chr3_+_129001581 10.30 ENST00000436022.2
EF-hand and coiled-coil domain containing 1
chr22_+_20117424 10.19 ENST00000402752.5
RAN binding protein 1
chr10_-_47484081 10.16 ENST00000583448.2
ENST00000583874.5
ENST00000585281.6
annexin A8
chr11_+_83156988 10.03 ENST00000298281.8
ENST00000530660.5
PCF11 cleavage and polyadenylation factor subunit
chr16_+_1984182 9.85 ENST00000248114.7
ENST00000569451.1
ENST00000561710.1
growth factor, augmenter of liver regeneration
chr11_-_6655788 9.83 ENST00000299441.5
dachsous cadherin-related 1
chr22_+_32801697 9.73 ENST00000266085.7
TIMP metallopeptidase inhibitor 3
chr1_+_11806096 9.72 ENST00000312413.10
ENST00000346436.11
chloride voltage-gated channel 6
chr16_+_50742059 9.69 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr22_-_38844020 9.67 ENST00000333039.4
neuronal pentraxin receptor
chr16_+_1706163 9.64 ENST00000250894.8
ENST00000673691.1
ENST00000356010.9
ENST00000610761.2
mitogen-activated protein kinase 8 interacting protein 3
chr3_+_10992175 9.64 ENST00000646702.1
solute carrier family 6 member 1
chr17_+_4143168 9.63 ENST00000577075.6
ENST00000301391.8
ENST00000575251.5
cytochrome b5 domain containing 2
chr14_-_90816381 9.62 ENST00000328459.11
tetratricopeptide repeat domain 7B
chr12_+_119178920 9.57 ENST00000281938.7
heat shock protein family B (small) member 8
chr3_+_129001298 9.46 ENST00000683648.1
EF-hand and coiled-coil domain containing 1
chr6_+_70413417 9.43 ENST00000505769.5
ENST00000515323.5
family with sequence similarity 135 member A
chr12_-_52452139 9.41 ENST00000252252.4
keratin 6B
chr10_+_46375645 9.39 ENST00000622769.4
annexin A8 like 1
chr9_+_124011738 9.28 ENST00000373615.9
LIM homeobox 2
chr17_+_40443441 9.23 ENST00000269593.5
insulin like growth factor binding protein 4
chr9_+_87498491 9.16 ENST00000622514.4
death associated protein kinase 1
chr19_+_53554819 9.14 ENST00000505949.5
ENST00000513265.5
ENST00000648511.1
zinc finger protein 331
chr17_-_73644435 8.96 ENST00000392650.8
sidekick cell adhesion molecule 2
chr16_+_56625775 8.91 ENST00000330439.7
ENST00000568293.1
metallothionein 1E
chr19_-_3971051 8.89 ENST00000545797.7
ENST00000596311.5
death associated protein kinase 3
chrX_+_23334841 8.88 ENST00000379361.5
patched domain containing 1
chr1_-_236281951 8.84 ENST00000354619.10
endoplasmic reticulum oxidoreductase 1 beta
chrX_-_107717054 8.83 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr12_+_32399517 8.79 ENST00000534526.7
FYVE, RhoGEF and PH domain containing 4
chr6_+_70413462 8.76 ENST00000418814.7
ENST00000515280.5
ENST00000507085.5
ENST00000457062.6
ENST00000361499.7
family with sequence similarity 135 member A
chr12_+_119178953 8.73 ENST00000674542.1
heat shock protein family B (small) member 8
chr16_+_1989949 8.63 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chr10_+_46375619 8.62 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr17_-_44324770 8.61 ENST00000592857.5
ENST00000586016.5
ENST00000590194.5
ENST00000588049.5
ENST00000586633.5
ENST00000377095.10
ENST00000537904.6
ENST00000585636.5
ENST00000585523.1
ENST00000225308.12
solute carrier family 25 member 39
chr12_+_6821646 8.61 ENST00000428545.6
G protein-coupled receptor 162
chr16_+_8674605 8.58 ENST00000268251.13
4-aminobutyrate aminotransferase
chr2_-_218010202 8.47 ENST00000646520.1
tensin 1
chr2_+_219627565 8.45 ENST00000273063.10
solute carrier family 4 member 3
chr7_+_144355288 8.39 ENST00000498580.5
ENST00000056217.10
Rho guanine nucleotide exchange factor 5
chr2_+_219627650 8.33 ENST00000317151.7
solute carrier family 4 member 3
chr11_+_46277648 8.21 ENST00000621158.5
cAMP responsive element binding protein 3 like 1
chr19_-_40414785 8.19 ENST00000674005.2
periaxin
chr19_+_57487711 8.18 ENST00000354197.8
ENST00000426954.6
ENST00000523882.5
ENST00000520540.5
ENST00000519310.1
ENST00000442920.6
ENST00000523312.1
ENST00000424930.6
zinc finger protein 419
chr19_-_48634526 8.16 ENST00000593500.1
ENST00000599385.5
D-box binding PAR bZIP transcription factor
chr10_-_98030612 8.13 ENST00000370597.8
cartilage acidic protein 1
chr11_-_66546021 8.13 ENST00000310442.5
zinc finger DHHC-type containing 24
chr9_-_124771238 8.12 ENST00000344523.8
ENST00000373584.7
nuclear receptor subfamily 6 group A member 1
chr4_-_119628791 8.09 ENST00000354960.8
phosphodiesterase 5A
chr5_+_17217617 8.07 ENST00000322611.4
brain abundant membrane attached signal protein 1
chr3_-_51499950 8.03 ENST00000423656.5
ENST00000504652.5
ENST00000684031.1
DDB1 and CUL4 associated factor 1
chr4_+_41256921 8.03 ENST00000284440.9
ENST00000508768.5
ENST00000512788.1
ubiquitin C-terminal hydrolase L1
chr12_+_130337872 7.99 ENST00000245255.7
piwi like RNA-mediated gene silencing 1
chr11_+_20669651 7.96 ENST00000532434.5
neural EGFL like 1
chr19_+_48364361 7.96 ENST00000344846.7
synaptogyrin 4
chrX_+_30653478 7.93 ENST00000378945.7
ENST00000378941.4
glycerol kinase
chr17_+_49495286 7.87 ENST00000172229.8
nerve growth factor receptor
chr11_-_62591554 7.84 ENST00000494385.1
ENST00000308436.11
terminal uridylyl transferase 1, U6 snRNA-specific
chr1_-_173824856 7.83 ENST00000682279.1
centromere protein L
chr6_-_34105965 7.82 ENST00000609222.5
glutamate metabotropic receptor 4
chr11_+_117144277 7.80 ENST00000419197.6
ENST00000527958.6
ENST00000304808.10
ENST00000529887.6
ENST00000530272.1
platelet activating factor acetylhydrolase 1b catalytic subunit 2
chrY_+_9466955 7.76 ENST00000423647.6
ENST00000451548.6
testis specific protein Y-linked 1
chr5_-_141618914 7.75 ENST00000518047.5
diaphanous related formin 1
chr22_-_38302990 7.72 ENST00000612795.2
ENST00000451964.5
casein kinase 1 epsilon
chrX_+_21839646 7.72 ENST00000365779.2
membrane bound transcription factor peptidase, site 2
chr8_+_103500696 7.71 ENST00000666250.1
ENST00000668113.1
ENST00000504942.6
ENST00000632716.1
regulating synaptic membrane exocytosis 2
chrX_+_30653359 7.70 ENST00000378943.7
ENST00000378946.7
ENST00000427190.6
glycerol kinase
chr19_+_57487735 7.66 ENST00000347466.10
ENST00000523138.5
ENST00000415379.6
ENST00000221735.12
ENST00000521754.5
zinc finger protein 419
chr5_+_178941186 7.63 ENST00000320129.7
ENST00000519564.2
zinc finger protein 454
chr22_+_22327298 7.61 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr19_-_49442360 7.56 ENST00000600601.5
solute carrier family 17 member 7
chr19_+_49361783 7.56 ENST00000594268.1
dickkopf like acrosomal protein 1
chr2_+_219627622 7.51 ENST00000358055.8
solute carrier family 4 member 3
chr4_+_158210479 7.44 ENST00000504569.5
ENST00000509278.5
ENST00000514558.5
ENST00000503200.5
ENST00000296529.11
transmembrane protein 144
chr2_+_147844601 7.42 ENST00000404590.1
activin A receptor type 2A
chr3_+_112333147 7.40 ENST00000473539.5
ENST00000315711.12
ENST00000383681.7
CD200 molecule
chr5_+_140966466 7.39 ENST00000615316.1
ENST00000289269.7
protocadherin alpha subfamily C, 2
chr1_+_151198536 7.35 ENST00000349792.9
ENST00000409426.5
ENST00000368888.9
ENST00000441902.6
ENST00000368890.8
ENST00000424999.1
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
chr8_-_21788853 7.34 ENST00000524240.6
GDNF family receptor alpha 2
chr15_+_84600986 7.31 ENST00000540936.1
ENST00000448803.6
ENST00000546275.1
ENST00000546148.6
ENST00000442073.3
ENST00000334141.7
ENST00000358472.3
ENST00000502939.2
ENST00000379358.7
ENST00000327179.6
zinc finger and SCAN domain containing 2
chr2_-_236168376 7.28 ENST00000306318.5
gastrulation brain homeobox 2
chr20_+_45881218 7.27 ENST00000372523.1
zinc finger SWIM-type containing 1
chr14_-_102509713 7.27 ENST00000286918.9
ankyrin repeat domain 9
chr3_+_14947680 7.23 ENST00000435454.5
ENST00000323373.10
nuclear receptor subfamily 2 group C member 2
chr21_-_46323806 7.22 ENST00000397680.5
ENST00000445935.5
ENST00000291691.12
ENST00000397682.7
chromosome 21 open reading frame 58
chr5_-_141878396 7.19 ENST00000503492.5
ENST00000287008.8
ENST00000394536.4
protocadherin 1
chr16_+_3046552 7.13 ENST00000336577.9
matrix metallopeptidase 25
chr1_+_14945775 7.12 ENST00000400797.3
kazrin, periplakin interacting protein
chr1_-_39771348 7.00 ENST00000327582.5
3-oxoacid CoA-transferase 2
chr19_+_53554499 6.97 ENST00000512387.6
ENST00000511567.5
zinc finger protein 331
chrX_+_21839599 6.95 ENST00000379484.10
membrane bound transcription factor peptidase, site 2
chr5_-_151686908 6.95 ENST00000231061.9
secreted protein acidic and cysteine rich
chr1_-_11805294 6.91 ENST00000413656.5
ENST00000376592.6
ENST00000376585.6
methylenetetrahydrofolate reductase
chr19_-_14848922 6.91 ENST00000641129.1
olfactory receptor family 7 subfamily A member 10
chr17_-_7614824 6.88 ENST00000571597.1
ENST00000250113.12
FMR1 autosomal homolog 2
chr16_+_56191728 6.87 ENST00000638705.1
ENST00000262494.12
G protein subunit alpha o1
chrY_-_22182923 6.85 ENST00000303766.12
ENST00000454978.2
RNA binding motif protein Y-linked family 1 member F
chr12_+_64780465 6.81 ENST00000542120.6
TBC1 domain family member 30
chr16_-_86555021 6.80 ENST00000565482.1
ENST00000564364.5
ENST00000561989.5
ENST00000568037.5
ENST00000634347.1
ENST00000543303.6
ENST00000381214.9
ENST00000360900.11
ENST00000546093.5
ENST00000569000.5
ENST00000562994.5
ENST00000561522.1
methenyltetrahydrofolate synthetase domain containing
chr11_+_63839173 6.80 ENST00000502399.7
ENST00000425897.3
ENST00000513765.7
ENST00000679216.1
microtubule affinity regulating kinase 2
chr6_-_34146080 6.79 ENST00000538487.7
ENST00000374181.8
glutamate metabotropic receptor 4
chr22_+_41469104 6.78 ENST00000677554.1
ENST00000466237.2
ENST00000216254.9
ENST00000678788.1
ENST00000676792.1
ENST00000677153.1
ENST00000396512.3
ENST00000678269.1
ENST00000677532.1
aconitase 2
chr11_+_118610374 6.78 ENST00000532639.3
pleckstrin homology like domain family B member 1
chrX_-_54183207 6.68 ENST00000375180.7
ENST00000328235.4
ENST00000477084.1
family with sequence similarity 120C
chr19_+_4304632 6.67 ENST00000597590.5
fibronectin type III and SPRY domain containing 1
chr1_-_150010675 6.62 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chr2_-_152099023 6.58 ENST00000201943.10
ENST00000427385.6
ENST00000539935.7
calcium voltage-gated channel auxiliary subunit beta 4
chr7_-_44490609 6.56 ENST00000355451.8
NudC domain containing 3
chr2_+_147844488 6.56 ENST00000535787.5
activin A receptor type 2A
chr19_+_54137740 6.51 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CCR4-NOT transcription complex subunit 3
chr19_+_3359563 6.50 ENST00000589123.5
ENST00000395111.7
ENST00000586919.5
nuclear factor I C
chr4_-_86357722 6.49 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
mitogen-activated protein kinase 10
chr17_+_42536226 6.48 ENST00000225927.7
N-acetyl-alpha-glucosaminidase
chr16_+_28824116 6.48 ENST00000568266.5
ataxin 2 like
chr7_+_27242796 6.47 ENST00000496902.7
even-skipped homeobox 1
chr2_+_218859794 6.44 ENST00000233948.4
Wnt family member 6
chr20_-_49484258 6.44 ENST00000635465.1
potassium voltage-gated channel subfamily B member 1
chr5_+_178130996 6.43 ENST00000515098.5
ENST00000502814.5
ENST00000313386.9
ENST00000507457.5
ENST00000508647.5
required for meiotic nuclear division 5 homolog B
chr20_+_23035312 6.41 ENST00000255008.5
somatostatin receptor 4
chr18_+_44680093 6.40 ENST00000426838.8
ENST00000677068.1
SET binding protein 1
chr15_+_70892809 6.36 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr19_-_49072699 6.33 ENST00000221444.2
potassium voltage-gated channel subfamily A member 7
chr18_+_24426633 6.33 ENST00000648078.1
ENST00000284202.9
impact RWD domain protein
chr5_+_150166770 6.32 ENST00000231656.13
caudal type homeobox 1
chr16_-_70685975 6.30 ENST00000338779.11
MTSS I-BAR domain containing 2
chrY_+_21511338 6.27 ENST00000383020.7
ENST00000619219.1
ENST00000439108.6
ENST00000303902.9
RNA binding motif protein Y-linked family 1 member B
RNA binding motif protein Y-linked family 1 member A1
chr17_-_1829818 6.25 ENST00000305513.12
SET and MYND domain containing 4
chrY_+_9487313 6.24 ENST00000440215.4
testis specific protein Y-linked 9, pseudogene
chr11_+_45847406 6.23 ENST00000443527.6
ENST00000616623.4
ENST00000616080.2
cryptochrome circadian regulator 2
chrX_-_47650488 6.22 ENST00000247161.7
ENST00000376983.8
ENST00000343894.8
ETS transcription factor ELK1
chr22_+_22357739 6.20 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr12_+_6821797 6.16 ENST00000311268.8
ENST00000382315.7
G protein-coupled receptor 162
chrY_+_6246223 6.15 ENST00000429039.5
ENST00000320701.8
ENST00000383042.1
testis specific protein Y-linked 2
chr19_-_12333626 6.14 ENST00000293725.10
zinc finger protein 563
chr2_+_219418369 6.13 ENST00000373960.4
desmin
chr7_+_94908230 6.11 ENST00000433881.5
protein phosphatase 1 regulatory subunit 9A
chr21_+_10521569 6.08 ENST00000612957.4
ENST00000427445.6
ENST00000612746.1
ENST00000618007.5
transmembrane phosphatase with tensin homology
chr9_-_124771304 6.08 ENST00000416460.6
ENST00000487099.7
nuclear receptor subfamily 6 group A member 1
chr19_-_51417791 6.07 ENST00000353836.9
sialic acid binding Ig like lectin 10
chrX_-_49073989 6.05 ENST00000376386.3
ENST00000553851.3
PRA1 domain family member 2
chrY_+_9337464 6.03 ENST00000426950.6
ENST00000640033.1
ENST00000383008.1
testis specific protein Y-linked 4
chr17_+_50532713 6.02 ENST00000503690.5
ENST00000514874.5
ENST00000268933.8
epsin 3
chr16_+_66427270 6.02 ENST00000536005.7
ENST00000622872.4
ENST00000299694.12
ENST00000561796.5
brain expressed associated with NEDD4 1
chr2_-_20225123 5.98 ENST00000254351.9
syndecan 1
chr1_+_220528333 5.94 ENST00000677505.1
microtubule affinity regulating kinase 1
chr6_-_6007511 5.93 ENST00000616243.1
neuritin 1
chrY_-_21918032 5.93 ENST00000382658.5
ENST00000382659.6
RNA binding motif protein Y-linked family 1 member E
chr19_+_43716070 5.86 ENST00000244314.6
immunity related GTPase cinema
chr21_-_32727889 5.83 ENST00000630077.3
ENST00000674204.1
synaptojanin 1
chr4_+_139454070 5.81 ENST00000305626.6
RAB33B, member RAS oncogene family
chr8_-_144103678 5.80 ENST00000398712.7
SHANK associated RH domain interactor
chr7_-_102517755 5.79 ENST00000306682.6
ENST00000465829.6
ENST00000541662.5
RAS p21 protein activator 4B
chr1_+_220528785 5.79 ENST00000678435.1
microtubule affinity regulating kinase 1
chr17_+_50560703 5.72 ENST00000359106.10
calcium voltage-gated channel subunit alpha1 G
chr19_-_39032525 5.72 ENST00000509137.6
ENST00000292853.9
F-box protein 27
chr3_+_138348823 5.66 ENST00000475711.5
ENST00000464896.5
muscle RAS oncogene homolog
chr1_+_35557435 5.65 ENST00000373253.7
neurochondrin
chr1_+_119414931 5.65 ENST00000543831.5
ENST00000433745.5
ENST00000369416.4
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 53.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
6.3 6.3 GO:0032058 positive regulation of translation in response to stress(GO:0032056) positive regulation of translational initiation in response to stress(GO:0032058)
6.3 18.9 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
5.3 21.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of type B pancreatic cell development(GO:2000077)
5.2 20.9 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
5.0 19.8 GO:1904980 positive regulation of endosome organization(GO:1904980)
4.5 40.7 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
3.8 30.5 GO:0007506 gonadal mesoderm development(GO:0007506)
3.6 18.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
3.6 10.8 GO:1990108 protein linear deubiquitination(GO:1990108)
3.2 9.7 GO:0036048 protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
3.2 9.6 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
3.2 9.6 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
2.7 10.9 GO:0019086 late viral transcription(GO:0019086)
2.7 8.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
2.6 10.3 GO:0048627 myoblast development(GO:0048627)
2.5 7.6 GO:0042137 sequestering of neurotransmitter(GO:0042137)
2.5 9.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
2.4 7.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
2.2 15.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
2.1 8.6 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
2.1 6.4 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
2.1 8.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
2.1 12.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
2.1 6.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
1.9 7.7 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
1.9 7.5 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
1.9 18.6 GO:1905146 lysosomal protein catabolic process(GO:1905146)
1.9 5.6 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
1.9 7.4 GO:1903971 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.9 11.2 GO:0014807 regulation of somitogenesis(GO:0014807)
1.8 5.5 GO:0071284 establishment of blood-nerve barrier(GO:0008065) cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
1.8 9.1 GO:0071233 cellular response to leucine(GO:0071233)
1.8 8.8 GO:0030070 insulin processing(GO:0030070)
1.8 8.8 GO:1990164 histone H2A phosphorylation(GO:1990164)
1.7 5.2 GO:0071529 cementum mineralization(GO:0071529)
1.7 6.7 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.6 4.9 GO:0036146 cellular response to mycotoxin(GO:0036146)
1.6 8.1 GO:2001074 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
1.6 11.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
1.6 8.0 GO:0007412 axon target recognition(GO:0007412)
1.6 11.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
1.6 7.9 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.4 4.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
1.4 12.8 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
1.4 5.5 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
1.4 4.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.4 4.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
1.3 8.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
1.3 3.9 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
1.3 6.4 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.3 3.8 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.2 2.5 GO:0021558 trochlear nerve development(GO:0021558)
1.2 3.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.2 3.6 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
1.2 20.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.2 7.0 GO:0046952 ketone body catabolic process(GO:0046952)
1.2 16.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
1.1 2.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.1 8.0 GO:0035093 piRNA metabolic process(GO:0034587) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.1 8.8 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.1 3.3 GO:0014876 negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876)
1.1 6.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
1.1 3.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
1.0 4.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.0 6.8 GO:0006102 isocitrate metabolic process(GO:0006102)
1.0 2.9 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.9 3.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.9 3.8 GO:0044026 DNA hypermethylation(GO:0044026)
0.9 2.8 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.9 8.3 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.9 4.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.9 15.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.9 13.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.9 51.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.9 2.6 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.9 3.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.9 6.0 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.8 1.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.8 2.5 GO:1900155 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.8 5.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.8 5.8 GO:0001714 endodermal cell fate specification(GO:0001714)
0.8 12.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.8 10.6 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.8 18.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.8 4.0 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.8 8.6 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.8 12.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.8 15.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.8 21.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.8 2.3 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.7 1.5 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.7 11.0 GO:0046548 retinal rod cell development(GO:0046548)
0.7 5.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.7 7.8 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.7 2.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.7 2.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.7 11.9 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.7 12.6 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.7 9.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.7 2.1 GO:0048382 mesendoderm development(GO:0048382)
0.7 4.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651) activation of phospholipase A2 activity(GO:0032431)
0.7 6.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.7 13.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.7 2.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.7 7.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.7 2.0 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.7 7.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.6 3.9 GO:0035063 nuclear speck organization(GO:0035063)
0.6 2.6 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.6 17.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.6 1.9 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.6 3.8 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.6 3.8 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.6 1.9 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.6 3.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.6 6.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.6 9.9 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.6 6.8 GO:0008298 intracellular mRNA localization(GO:0008298)
0.6 7.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.6 1.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.6 3.0 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.6 7.3 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.6 9.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.6 3.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.6 8.9 GO:0021794 thalamus development(GO:0021794)
0.6 6.9 GO:0009629 response to gravity(GO:0009629)
0.6 3.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.6 9.8 GO:0031033 myosin filament organization(GO:0031033)
0.6 2.9 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.6 4.0 GO:0016198 axon choice point recognition(GO:0016198)
0.6 2.3 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.6 17.5 GO:0001825 blastocyst formation(GO:0001825)
0.6 17.4 GO:0021772 olfactory bulb development(GO:0021772)
0.6 3.3 GO:0007296 vitellogenesis(GO:0007296)
0.5 4.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.5 6.8 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.5 30.4 GO:0015701 bicarbonate transport(GO:0015701)
0.5 5.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.5 7.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.5 4.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.5 5.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.5 2.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.5 6.6 GO:0060009 Sertoli cell development(GO:0060009)
0.5 2.4 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.5 4.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.5 3.7 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.5 4.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.5 13.8 GO:0031643 positive regulation of myelination(GO:0031643)
0.5 10.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.4 1.8 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072) response to fluoride(GO:1902617)
0.4 3.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.4 3.1 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.4 3.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.4 2.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4 17.9 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.4 11.5 GO:0007398 ectoderm development(GO:0007398)
0.4 6.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 2.1 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.4 1.2 GO:0048880 sensory system development(GO:0048880)
0.4 8.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.4 7.1 GO:0060022 hard palate development(GO:0060022)
0.4 3.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.4 1.5 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.4 5.3 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.4 1.9 GO:0033504 floor plate development(GO:0033504)
0.4 6.8 GO:0032098 regulation of appetite(GO:0032098)
0.4 3.4 GO:0046078 dUMP metabolic process(GO:0046078)
0.4 1.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 5.7 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.4 3.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 8.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.3 1.7 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.3 1.0 GO:1901529 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.3 1.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 2.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.3 3.7 GO:0015801 aromatic amino acid transport(GO:0015801)
0.3 2.3 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.3 0.6 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.3 3.2 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.3 4.4 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.3 0.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.3 2.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 15.7 GO:0021762 substantia nigra development(GO:0021762)
0.3 3.5 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.3 3.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.3 0.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.3 4.3 GO:0006600 creatine metabolic process(GO:0006600)
0.3 0.9 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 4.6 GO:0048535 lymph node development(GO:0048535)
0.3 1.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 6.1 GO:0045109 intermediate filament organization(GO:0045109)
0.3 9.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.3 4.7 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.3 10.0 GO:0033014 tetrapyrrole biosynthetic process(GO:0033014)
0.3 5.5 GO:0007614 short-term memory(GO:0007614)
0.2 7.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 2.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 9.3 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 1.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 8.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 4.0 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 1.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 1.8 GO:0070995 NADPH oxidation(GO:0070995)
0.2 4.4 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.2 4.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 1.6 GO:0007000 nucleolus organization(GO:0007000)
0.2 4.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 5.5 GO:0060037 pharyngeal system development(GO:0060037)
0.2 1.8 GO:0090168 Golgi reassembly(GO:0090168)
0.2 7.8 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 2.5 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 1.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 7.1 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2 12.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 0.4 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.2 0.4 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.2 4.8 GO:0043029 T cell homeostasis(GO:0043029)
0.2 3.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 3.5 GO:0010842 retina layer formation(GO:0010842)
0.2 7.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 4.6 GO:0009299 mRNA transcription(GO:0009299)
0.2 4.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 21.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 12.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 12.2 GO:0006611 protein export from nucleus(GO:0006611)
0.2 5.2 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.2 3.0 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.2 4.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 1.5 GO:0021815 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.2 2.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 1.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 1.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 5.0 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.2 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 2.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 6.5 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 0.7 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 5.1 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 5.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 3.9 GO:0007602 phototransduction(GO:0007602)
0.1 5.5 GO:1901998 toxin transport(GO:1901998)
0.1 3.2 GO:0006379 mRNA cleavage(GO:0006379)
0.1 6.6 GO:0030317 sperm motility(GO:0030317)
0.1 5.2 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 22.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 4.9 GO:0010107 potassium ion import(GO:0010107)
0.1 6.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 2.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 4.0 GO:0007625 grooming behavior(GO:0007625)
0.1 3.0 GO:0015800 acidic amino acid transport(GO:0015800)
0.1 5.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 1.2 GO:1904646 cellular response to beta-amyloid(GO:1904646)
0.1 4.1 GO:0035904 aorta development(GO:0035904)
0.1 1.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 17.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 3.2 GO:0003016 respiratory system process(GO:0003016)
0.1 7.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 3.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 5.7 GO:0051646 mitochondrion localization(GO:0051646)
0.1 0.4 GO:0032904 viral protein processing(GO:0019082) negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 3.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.4 GO:0030252 growth hormone secretion(GO:0030252)
0.1 3.9 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 3.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 3.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 3.9 GO:0010761 fibroblast migration(GO:0010761)
0.1 13.7 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.1 1.2 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 1.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 2.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 4.9 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 4.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 1.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 6.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 4.6 GO:0006334 nucleosome assembly(GO:0006334)
0.1 4.5 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1 0.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 2.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 2.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 2.4 GO:0051693 actin filament capping(GO:0051693)
0.1 1.6 GO:0007099 centriole replication(GO:0007099)
0.1 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 3.4 GO:0006953 acute-phase response(GO:0006953)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.1 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.1 2.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 6.7 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 6.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 2.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 2.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.0 GO:0031648 protein destabilization(GO:0031648)
0.0 2.4 GO:0008585 female gonad development(GO:0008585)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 2.3 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 1.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 3.5 GO:0003014 renal system process(GO:0003014)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 2.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.5 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.8 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 1.0 GO:0030282 bone mineralization(GO:0030282)
0.0 4.5 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 18.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
2.1 8.6 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
2.1 6.4 GO:0034657 GID complex(GO:0034657)
1.9 32.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.4 5.5 GO:0019034 viral replication complex(GO:0019034)
1.3 8.0 GO:0031501 mannosyltransferase complex(GO:0031501)
1.3 15.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.2 7.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.1 3.4 GO:0031251 PAN complex(GO:0031251)
1.1 13.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
1.1 12.8 GO:0016342 catenin complex(GO:0016342)
1.1 23.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.1 8.4 GO:0034464 BBSome(GO:0034464)
1.0 5.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.0 5.8 GO:0071797 LUBAC complex(GO:0071797)
0.9 7.6 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.9 8.0 GO:0033391 chromatoid body(GO:0033391)
0.9 7.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.9 6.1 GO:0044326 dendritic spine neck(GO:0044326)
0.9 8.6 GO:0045180 basal cortex(GO:0045180)
0.8 18.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.8 4.7 GO:0002177 manchette(GO:0002177)
0.8 3.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 5.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.7 7.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.7 5.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.7 28.7 GO:0045095 keratin filament(GO:0045095)
0.7 4.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.7 4.0 GO:0032279 asymmetric synapse(GO:0032279)
0.7 13.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 2.0 GO:0043260 laminin-11 complex(GO:0043260)
0.6 7.0 GO:0005638 lamin filament(GO:0005638)
0.6 6.8 GO:0097427 microtubule bundle(GO:0097427)
0.5 7.1 GO:0030057 desmosome(GO:0030057)
0.5 6.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.5 3.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.5 12.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 5.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.5 16.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.5 0.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.4 1.8 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.4 7.0 GO:0097512 cardiac myofibril(GO:0097512)
0.4 2.2 GO:1990031 pinceau fiber(GO:1990031)
0.4 3.9 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.4 2.1 GO:0032044 DSIF complex(GO:0032044)
0.4 2.5 GO:1990769 proximal neuron projection(GO:1990769)
0.4 4.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 2.0 GO:0045160 myosin I complex(GO:0045160)
0.4 4.5 GO:0030897 HOPS complex(GO:0030897)
0.4 3.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.3 3.8 GO:0005915 zonula adherens(GO:0005915)
0.3 5.5 GO:0000800 lateral element(GO:0000800)
0.3 18.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 7.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 6.5 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.3 1.5 GO:0044327 dendritic spine head(GO:0044327)
0.3 7.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.3 4.9 GO:0000786 nucleosome(GO:0000786)
0.3 10.8 GO:0097542 ciliary tip(GO:0097542)
0.3 18.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 43.4 GO:0031225 anchored component of membrane(GO:0031225)
0.3 7.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 6.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.3 6.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 16.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 7.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 1.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 11.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 11.3 GO:0048786 presynaptic active zone(GO:0048786)
0.2 13.2 GO:0005844 polysome(GO:0005844)
0.2 5.9 GO:0005685 U1 snRNP(GO:0005685)
0.2 16.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 1.1 GO:0044308 axonal spine(GO:0044308)
0.2 6.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 24.6 GO:0005796 Golgi lumen(GO:0005796)
0.2 14.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 3.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 9.2 GO:0008180 COP9 signalosome(GO:0008180)
0.2 1.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 2.8 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 9.8 GO:0031526 brush border membrane(GO:0031526)
0.2 16.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 1.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 9.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 19.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 18.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 5.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.8 GO:0031082 BLOC complex(GO:0031082)
0.1 8.2 GO:0005814 centriole(GO:0005814)
0.1 5.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.3 GO:0043194 axon initial segment(GO:0043194)
0.1 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 10.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 5.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 6.3 GO:0031514 motile cilium(GO:0031514)
0.1 8.7 GO:0005884 actin filament(GO:0005884)
0.1 7.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.4 GO:0008021 synaptic vesicle(GO:0008021)
0.1 5.1 GO:0005581 collagen trimer(GO:0005581)
0.1 9.5 GO:0009986 cell surface(GO:0009986)
0.1 2.4 GO:0030673 axolemma(GO:0030673)
0.1 13.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 100.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 3.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.9 GO:0005882 intermediate filament(GO:0005882)
0.0 1.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 6.6 GO:0001650 fibrillar center(GO:0001650)
0.0 1.7 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 3.5 GO:0005643 nuclear pore(GO:0005643)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 3.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.7 GO:0072562 blood microparticle(GO:0072562)
0.0 41.8 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 53.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
4.0 11.9 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
3.6 18.2 GO:0004370 glycerol kinase activity(GO:0004370)
3.5 10.6 GO:0005137 interleukin-5 receptor binding(GO:0005137)
3.2 9.7 GO:0061697 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
3.0 12.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
2.8 19.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
2.7 8.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
2.6 12.9 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
2.6 7.7 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
2.5 10.2 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
2.5 15.2 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
2.2 6.7 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
2.1 8.6 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
2.1 55.1 GO:0031489 myosin V binding(GO:0031489)
2.0 34.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.9 7.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
1.9 15.4 GO:0098821 BMP receptor activity(GO:0098821)
1.9 11.3 GO:0031708 endothelin B receptor binding(GO:0031708)
1.8 5.5 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
1.7 6.8 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
1.6 4.9 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.6 8.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.6 7.8 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.5 42.9 GO:0050321 tau-protein kinase activity(GO:0050321)
1.5 30.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.5 9.1 GO:0070728 leucine binding(GO:0070728)
1.5 7.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.5 12.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.5 7.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.4 5.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
1.4 7.0 GO:0001594 trace-amine receptor activity(GO:0001594)
1.4 7.0 GO:0008410 CoA-transferase activity(GO:0008410)
1.4 5.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.4 4.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.3 6.4 GO:0004994 somatostatin receptor activity(GO:0004994)
1.2 16.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.2 5.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.1 5.6 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.1 17.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
1.1 12.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.1 3.2 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
1.1 5.3 GO:0070097 delta-catenin binding(GO:0070097)
1.0 7.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.0 5.1 GO:0005119 smoothened binding(GO:0005119)
1.0 4.0 GO:0070905 serine binding(GO:0070905)
1.0 8.8 GO:0043426 MRF binding(GO:0043426)
0.9 5.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.9 4.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.9 5.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.9 24.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.8 3.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.8 12.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.8 11.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.7 3.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.7 4.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.7 4.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.7 2.1 GO:0005055 laminin receptor activity(GO:0005055)
0.7 8.7 GO:0042608 T cell receptor binding(GO:0042608)
0.7 4.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.7 4.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.7 10.5 GO:0048185 activin binding(GO:0048185)
0.6 2.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.6 3.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.6 8.8 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.6 8.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.6 3.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.6 4.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.6 5.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.5 4.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.5 4.3 GO:0004111 creatine kinase activity(GO:0004111)
0.5 2.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.5 3.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 2.6 GO:1990254 keratin filament binding(GO:1990254)
0.5 5.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.5 6.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.5 2.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.5 8.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 9.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 9.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 7.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.4 3.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 8.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4 3.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 2.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.4 7.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 17.5 GO:0008066 glutamate receptor activity(GO:0008066)
0.4 4.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 6.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.4 1.5 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.4 8.0 GO:0005112 Notch binding(GO:0005112)
0.4 1.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.4 12.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 12.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.4 2.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 6.2 GO:0009881 photoreceptor activity(GO:0009881)
0.4 3.3 GO:0089720 caspase binding(GO:0089720)
0.4 3.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.4 11.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 15.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 6.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 35.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 3.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 4.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 2.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 1.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.3 2.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 0.9 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.3 2.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 2.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.3 1.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.3 1.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.3 1.9 GO:0045545 syndecan binding(GO:0045545)
0.3 18.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.3 7.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 3.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.3 1.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 2.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 1.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 3.0 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 3.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 12.9 GO:0042169 SH2 domain binding(GO:0042169)
0.2 29.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 6.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 26.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 0.7 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.2 6.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 6.5 GO:0005109 frizzled binding(GO:0005109)
0.2 3.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 3.9 GO:0031005 filamin binding(GO:0031005)
0.2 5.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 9.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 3.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 3.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 1.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 3.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 3.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 12.8 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.2 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.2 1.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 8.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 28.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 0.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 6.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 19.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.2 9.6 GO:0030507 spectrin binding(GO:0030507)
0.2 1.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 2.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 2.1 GO:0034452 dynactin binding(GO:0034452)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 5.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 6.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 1.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 6.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.4 GO:0043495 protein anchor(GO:0043495)
0.1 18.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 10.3 GO:0052813 phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.9 GO:0031432 titin binding(GO:0031432)
0.1 0.8 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 7.0 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.1 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 8.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 7.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 9.7 GO:0002039 p53 binding(GO:0002039)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 4.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.6 GO:0035497 cAMP response element binding(GO:0035497)
0.1 12.8 GO:0001618 virus receptor activity(GO:0001618)
0.1 3.2 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.1 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.4 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.5 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 5.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 5.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 21.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 67.7 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.8 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 4.5 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 4.1 GO:0005507 copper ion binding(GO:0005507)
0.1 4.1 GO:0043022 ribosome binding(GO:0043022)
0.1 9.8 GO:0051015 actin filament binding(GO:0051015)
0.1 10.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 3.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 6.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 3.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 8.0 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 3.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.7 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 17.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.6 GO:0020037 heme binding(GO:0020037)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 4.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.8 26.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.6 17.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.6 4.2 NABA COLLAGENS Genes encoding collagen proteins
0.5 9.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.5 20.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.5 21.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 9.0 PID IL5 PATHWAY IL5-mediated signaling events
0.4 14.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4 7.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 27.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.4 10.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 15.9 PID ALK1 PATHWAY ALK1 signaling events
0.4 15.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 26.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 42.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 12.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 7.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 4.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 13.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 15.2 PID NOTCH PATHWAY Notch signaling pathway
0.2 5.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 7.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 7.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 3.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 12.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 12.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 30.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 5.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 8.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 13.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 14.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 5.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 1.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 4.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 3.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.5 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 2.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 13.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 22.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.3 21.7 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
1.1 21.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
1.0 20.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.8 64.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.7 10.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.7 1.4 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.7 4.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.7 9.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 7.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.5 17.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.5 3.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.5 12.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 20.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.5 22.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 8.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5 12.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.5 33.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.5 6.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 0.8 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.4 16.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 7.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.4 5.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.4 7.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 8.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 12.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 6.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3 29.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 14.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 11.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 17.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.3 16.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 15.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 7.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 11.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 8.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 32.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 3.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 4.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 1.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 3.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 1.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 4.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 3.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 9.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 55.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.2 5.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 10.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 2.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 5.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 3.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 2.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 3.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 7.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 10.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 13.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 6.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 10.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 2.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 2.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane