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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ZEB1
Z-value: 5.97
Motif logo
Transcription factors associated with ZEB1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ZEB1
|
ENSG00000148516.23 | ZEB1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZEB1 | hg38_v1_chr10_+_31321152_31321230 | -0.23 | 6.0e-04 | Click! |
Activity profile of ZEB1 motif
Sorted Z-values of ZEB1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ZEB1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 37.9 | 227.7 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 35.6 | 106.8 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 18.4 | 73.8 | GO:0002159 | desmosome assembly(GO:0002159) |
| 12.4 | 37.3 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 9.1 | 54.4 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 8.8 | 26.4 | GO:0048817 | negative regulation of hair follicle maturation(GO:0048817) |
| 8.3 | 33.2 | GO:0032913 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
| 8.2 | 74.1 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 8.2 | 41.2 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 7.0 | 49.2 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 6.7 | 26.8 | GO:0090301 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 6.7 | 26.7 | GO:0072302 | posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
| 6.5 | 26.0 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 6.3 | 25.2 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 6.2 | 24.8 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 6.2 | 61.8 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 6.0 | 6.0 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
| 6.0 | 17.9 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 5.9 | 29.5 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 5.9 | 76.4 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 5.8 | 17.4 | GO:1904582 | regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582) |
| 5.8 | 23.1 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) |
| 5.7 | 17.0 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 5.6 | 22.4 | GO:0048627 | myoblast development(GO:0048627) |
| 5.6 | 16.7 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 5.6 | 16.7 | GO:0009720 | detection of hormone stimulus(GO:0009720) |
| 5.5 | 21.8 | GO:0044407 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) |
| 5.4 | 27.2 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 5.3 | 16.0 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) |
| 5.2 | 15.7 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 5.2 | 15.6 | GO:0035054 | embryonic heart tube anterior/posterior pattern specification(GO:0035054) |
| 5.2 | 36.2 | GO:0090191 | negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) |
| 5.2 | 15.5 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 5.1 | 15.2 | GO:0007354 | zygotic determination of anterior/posterior axis, embryo(GO:0007354) |
| 5.1 | 20.3 | GO:0051142 | regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) |
| 5.0 | 39.9 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 4.8 | 24.2 | GO:0060480 | lung goblet cell differentiation(GO:0060480) |
| 4.8 | 19.2 | GO:0009305 | protein biotinylation(GO:0009305) histone biotinylation(GO:0071110) |
| 4.8 | 14.3 | GO:0060974 | neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) |
| 4.6 | 18.5 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 4.6 | 13.8 | GO:2001153 | regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153) |
| 4.6 | 13.7 | GO:0100009 | regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 4.5 | 18.0 | GO:0000430 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) |
| 4.4 | 17.8 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 4.4 | 13.2 | GO:1902161 | positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) |
| 4.4 | 4.4 | GO:2000374 | regulation of oxygen metabolic process(GO:2000374) |
| 4.2 | 134.5 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 4.2 | 8.4 | GO:0035502 | metanephric part of ureteric bud development(GO:0035502) |
| 4.1 | 16.4 | GO:0002357 | defense response to tumor cell(GO:0002357) |
| 4.1 | 8.1 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
| 4.0 | 16.1 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 4.0 | 8.0 | GO:0035759 | mesangial cell-matrix adhesion(GO:0035759) |
| 4.0 | 15.8 | GO:2000170 | positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
| 3.9 | 19.5 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 3.9 | 15.5 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 3.9 | 19.4 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 3.9 | 7.7 | GO:0033861 | negative regulation of NAD(P)H oxidase activity(GO:0033861) |
| 3.9 | 11.6 | GO:1901624 | negative regulation of lymphocyte chemotaxis(GO:1901624) |
| 3.8 | 11.5 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 3.8 | 11.5 | GO:1901994 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 3.8 | 3.8 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 3.8 | 11.4 | GO:0070077 | peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079) |
| 3.8 | 11.3 | GO:0019056 | modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
| 3.8 | 11.3 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 3.7 | 14.9 | GO:0009137 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 3.7 | 14.9 | GO:2000569 | T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
| 3.7 | 11.1 | GO:0071464 | cellular response to hydrostatic pressure(GO:0071464) |
| 3.7 | 33.3 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 3.7 | 3.7 | GO:2001280 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 3.6 | 18.2 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 3.6 | 10.8 | GO:0007500 | mesodermal cell fate determination(GO:0007500) |
| 3.6 | 3.6 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 3.6 | 14.3 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 3.5 | 14.2 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 3.5 | 21.1 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 3.5 | 10.5 | GO:0097535 | lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) |
| 3.5 | 10.4 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 3.5 | 10.4 | GO:1902595 | regulation of DNA replication origin binding(GO:1902595) |
| 3.5 | 3.5 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 3.4 | 61.8 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 3.4 | 10.2 | GO:0035691 | macrophage migration inhibitory factor signaling pathway(GO:0035691) |
| 3.4 | 33.5 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 3.3 | 9.9 | GO:0002414 | immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 3.3 | 9.9 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 3.3 | 42.4 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 3.2 | 16.1 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 3.2 | 12.9 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 3.2 | 22.5 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 3.2 | 3.2 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 3.2 | 12.7 | GO:0006562 | proline catabolic process(GO:0006562) |
| 3.1 | 6.3 | GO:2001274 | negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 3.1 | 18.8 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 3.1 | 21.8 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 3.1 | 6.2 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 3.0 | 24.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 3.0 | 5.9 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
| 2.9 | 14.7 | GO:0030070 | insulin processing(GO:0030070) |
| 2.9 | 8.8 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 2.9 | 5.8 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
| 2.9 | 11.6 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 2.9 | 8.6 | GO:0071206 | establishment of protein localization to juxtaparanode region of axon(GO:0071206) |
| 2.9 | 8.6 | GO:0009134 | nucleoside diphosphate catabolic process(GO:0009134) |
| 2.8 | 11.3 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 2.8 | 39.2 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 2.8 | 11.2 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 2.8 | 38.8 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 2.8 | 8.3 | GO:0060023 | soft palate development(GO:0060023) |
| 2.7 | 8.2 | GO:0051673 | pore formation in membrane of other organism(GO:0035915) membrane disruption in other organism(GO:0051673) |
| 2.7 | 8.2 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 2.7 | 8.2 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 2.7 | 19.1 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 2.7 | 8.2 | GO:0070662 | mast cell proliferation(GO:0070662) |
| 2.7 | 10.9 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 2.7 | 8.1 | GO:0002125 | maternal aggressive behavior(GO:0002125) |
| 2.7 | 32.0 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 2.7 | 2.7 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 2.7 | 34.6 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 2.7 | 5.3 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 2.7 | 8.0 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 2.7 | 2.7 | GO:0086042 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) |
| 2.6 | 7.9 | GO:0009644 | response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009) |
| 2.6 | 21.0 | GO:0070236 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 2.6 | 2.6 | GO:0048617 | foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617) |
| 2.6 | 7.9 | GO:0071529 | cementum mineralization(GO:0071529) |
| 2.6 | 18.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 2.6 | 7.7 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 2.6 | 2.6 | GO:0010841 | positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) |
| 2.6 | 10.3 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 2.6 | 20.5 | GO:0006203 | dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061) |
| 2.6 | 15.4 | GO:0010749 | regulation of nitric oxide mediated signal transduction(GO:0010749) |
| 2.6 | 7.7 | GO:0051039 | histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 2.6 | 25.5 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 2.5 | 5.1 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
| 2.5 | 2.5 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 2.5 | 68.1 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 2.5 | 10.1 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 2.5 | 9.8 | GO:0043091 | L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023) |
| 2.4 | 9.7 | GO:0010979 | regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) |
| 2.4 | 9.7 | GO:0042223 | response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of gamma-delta T cell differentiation(GO:0045588) cellular response to molecule of fungal origin(GO:0071226) |
| 2.4 | 7.1 | GO:0021558 | trochlear nerve development(GO:0021558) |
| 2.4 | 7.1 | GO:0098902 | regulation of membrane depolarization during action potential(GO:0098902) |
| 2.4 | 7.1 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) glomerular visceral epithelial cell migration(GO:0090521) |
| 2.4 | 23.6 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 2.4 | 9.4 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 2.4 | 7.1 | GO:0016103 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
| 2.3 | 11.7 | GO:0015811 | L-cystine transport(GO:0015811) |
| 2.3 | 4.6 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 2.3 | 4.6 | GO:0034226 | response to muscle activity involved in regulation of muscle adaptation(GO:0014873) lysine transport(GO:0015819) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transport(GO:1902022) L-lysine import into cell(GO:1903410) |
| 2.3 | 9.3 | GO:0090194 | negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) |
| 2.3 | 6.9 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 2.3 | 6.9 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 2.3 | 11.4 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 2.3 | 6.8 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 2.3 | 11.3 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 2.3 | 11.3 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 2.3 | 6.8 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 2.3 | 9.0 | GO:0086021 | SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
| 2.3 | 11.3 | GO:0060214 | endocardium formation(GO:0060214) |
| 2.2 | 9.0 | GO:0036269 | swimming behavior(GO:0036269) |
| 2.2 | 15.5 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 2.2 | 6.6 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 2.2 | 6.6 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 2.2 | 4.4 | GO:0072177 | mesonephric duct development(GO:0072177) |
| 2.2 | 6.6 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 2.2 | 13.2 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 2.2 | 6.6 | GO:0061590 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 2.2 | 6.5 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 2.2 | 13.0 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 2.2 | 4.3 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 2.2 | 4.3 | GO:1902809 | skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 2.1 | 4.3 | GO:0000429 | carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) |
| 2.1 | 21.3 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 2.1 | 6.4 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 2.1 | 12.6 | GO:0070829 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 2.1 | 35.7 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
| 2.1 | 12.6 | GO:0006489 | dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465) |
| 2.1 | 6.2 | GO:0008078 | mesodermal cell migration(GO:0008078) |
| 2.1 | 12.5 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 2.1 | 8.3 | GO:0003431 | growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) |
| 2.1 | 8.2 | GO:1990737 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 2.1 | 6.2 | GO:0036292 | DNA rewinding(GO:0036292) |
| 2.1 | 10.3 | GO:0010481 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 2.0 | 26.6 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 2.0 | 10.2 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 2.0 | 38.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 2.0 | 12.3 | GO:0070673 | response to interleukin-18(GO:0070673) |
| 2.0 | 16.3 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 2.0 | 6.1 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 2.0 | 6.1 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 2.0 | 6.0 | GO:0090274 | regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274) |
| 2.0 | 6.0 | GO:0002461 | tolerance induction dependent upon immune response(GO:0002461) |
| 2.0 | 15.7 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 2.0 | 3.9 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 2.0 | 9.8 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 1.9 | 3.9 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 1.9 | 5.6 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 1.9 | 24.4 | GO:0038065 | collagen-activated signaling pathway(GO:0038065) |
| 1.9 | 18.7 | GO:0021633 | optic nerve structural organization(GO:0021633) |
| 1.9 | 9.3 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 1.8 | 5.5 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
| 1.8 | 5.5 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 1.8 | 11.0 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 1.8 | 9.1 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 1.8 | 7.2 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 1.8 | 7.2 | GO:0097021 | lymphocyte migration into lymphoid organs(GO:0097021) |
| 1.8 | 5.4 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 1.8 | 18.0 | GO:0006857 | oligopeptide transport(GO:0006857) |
| 1.8 | 16.2 | GO:1904152 | regulation of retrograde protein transport, ER to cytosol(GO:1904152) |
| 1.8 | 1.8 | GO:0098908 | regulation of neuronal action potential(GO:0098908) |
| 1.8 | 26.6 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
| 1.8 | 5.3 | GO:0030573 | bile acid catabolic process(GO:0030573) |
| 1.7 | 7.0 | GO:0051697 | protein delipidation(GO:0051697) |
| 1.7 | 1.7 | GO:1903061 | regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) |
| 1.7 | 3.4 | GO:1901859 | negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) |
| 1.7 | 6.9 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 1.7 | 6.9 | GO:0072104 | glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) |
| 1.7 | 8.6 | GO:0016926 | protein desumoylation(GO:0016926) |
| 1.7 | 15.4 | GO:0046549 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 1.7 | 3.4 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
| 1.7 | 15.2 | GO:0060750 | thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) |
| 1.7 | 45.7 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 1.7 | 1.7 | GO:0019532 | oxalate transport(GO:0019532) |
| 1.7 | 10.1 | GO:0042640 | anagen(GO:0042640) |
| 1.7 | 6.7 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 1.7 | 15.0 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 1.7 | 5.0 | GO:0008595 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 1.6 | 8.2 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 1.6 | 3.3 | GO:0003418 | growth plate cartilage chondrocyte differentiation(GO:0003418) |
| 1.6 | 4.9 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 1.6 | 8.0 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 1.6 | 9.6 | GO:0010734 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 1.6 | 4.8 | GO:0044278 | cell wall disruption in other organism(GO:0044278) |
| 1.6 | 6.3 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 1.6 | 3.2 | GO:0019086 | late viral transcription(GO:0019086) |
| 1.6 | 48.8 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) |
| 1.6 | 7.9 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
| 1.6 | 59.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 1.5 | 12.4 | GO:0002093 | auditory receptor cell morphogenesis(GO:0002093) |
| 1.5 | 6.2 | GO:2000638 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 1.5 | 4.6 | GO:0021718 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 1.5 | 7.5 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 1.5 | 209.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 1.5 | 6.0 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 1.5 | 20.8 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 1.5 | 4.5 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 1.5 | 4.4 | GO:0000963 | mitochondrial RNA processing(GO:0000963) |
| 1.5 | 1.5 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 1.5 | 10.2 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 1.5 | 11.6 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 1.4 | 32.9 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 1.4 | 8.5 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 1.4 | 2.8 | GO:0060268 | negative regulation of respiratory burst(GO:0060268) |
| 1.4 | 7.1 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 1.4 | 12.7 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 1.4 | 4.2 | GO:0072608 | interleukin-10 secretion(GO:0072608) mature conventional dendritic cell differentiation(GO:0097029) |
| 1.4 | 2.8 | GO:0072011 | glomerular endothelium development(GO:0072011) |
| 1.4 | 4.2 | GO:1901877 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 1.4 | 2.8 | GO:0048852 | hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852) |
| 1.4 | 9.7 | GO:0006707 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 1.4 | 8.3 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 1.4 | 4.1 | GO:0070945 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) |
| 1.4 | 8.3 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 1.4 | 6.8 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 1.4 | 9.6 | GO:0061370 | testosterone biosynthetic process(GO:0061370) |
| 1.4 | 8.2 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 1.4 | 6.8 | GO:0061364 | apoptotic process involved in luteolysis(GO:0061364) |
| 1.3 | 2.7 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) |
| 1.3 | 4.0 | GO:0030035 | microspike assembly(GO:0030035) |
| 1.3 | 8.1 | GO:0071910 | determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910) |
| 1.3 | 10.8 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 1.3 | 12.1 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 1.3 | 13.4 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 1.3 | 6.7 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 1.3 | 5.4 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 1.3 | 2.7 | GO:0061047 | positive regulation of branching involved in lung morphogenesis(GO:0061047) |
| 1.3 | 13.4 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
| 1.3 | 4.0 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 1.3 | 2.7 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
| 1.3 | 8.0 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) |
| 1.3 | 6.6 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 1.3 | 11.9 | GO:1900165 | negative regulation of interleukin-6 secretion(GO:1900165) |
| 1.3 | 11.9 | GO:0060174 | limb bud formation(GO:0060174) |
| 1.3 | 7.9 | GO:1904995 | negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
| 1.3 | 3.9 | GO:0036049 | protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699) |
| 1.3 | 2.6 | GO:1903413 | cellular response to bile acid(GO:1903413) |
| 1.3 | 5.2 | GO:0032847 | cochlear nucleus development(GO:0021747) regulation of cellular pH reduction(GO:0032847) negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 1.3 | 11.6 | GO:0046959 | habituation(GO:0046959) |
| 1.3 | 6.4 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 1.3 | 3.8 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 1.3 | 3.8 | GO:0060032 | notochord regression(GO:0060032) |
| 1.3 | 54.5 | GO:0098927 | vesicle-mediated transport between endosomal compartments(GO:0098927) |
| 1.3 | 17.7 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 1.3 | 8.8 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 1.3 | 10.0 | GO:0021636 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
| 1.2 | 12.5 | GO:0097688 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 1.2 | 8.7 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 1.2 | 6.2 | GO:0016240 | autophagosome docking(GO:0016240) |
| 1.2 | 15.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 1.2 | 8.6 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 1.2 | 13.4 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
| 1.2 | 11.0 | GO:0032119 | sequestering of zinc ion(GO:0032119) |
| 1.2 | 2.4 | GO:0072205 | metanephric collecting duct development(GO:0072205) |
| 1.2 | 13.3 | GO:0014029 | neural crest formation(GO:0014029) |
| 1.2 | 4.8 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 1.2 | 6.0 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 1.2 | 2.4 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 1.2 | 9.6 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) |
| 1.2 | 21.5 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 1.2 | 21.4 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 1.2 | 3.5 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) |
| 1.2 | 5.8 | GO:0007000 | nucleolus organization(GO:0007000) |
| 1.2 | 5.8 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 1.2 | 8.1 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 1.2 | 6.9 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 1.2 | 32.3 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 1.2 | 9.2 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 1.1 | 10.3 | GO:1904259 | positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 1.1 | 4.6 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 1.1 | 15.9 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 1.1 | 2.3 | GO:0043697 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 1.1 | 6.7 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 1.1 | 5.6 | GO:0045872 | regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872) |
| 1.1 | 5.6 | GO:0001553 | luteinization(GO:0001553) |
| 1.1 | 109.0 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 1.1 | 8.9 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 1.1 | 5.5 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 1.1 | 4.4 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 1.1 | 2.2 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 1.1 | 3.3 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 1.1 | 12.9 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 1.1 | 4.3 | GO:0048880 | sensory system development(GO:0048880) |
| 1.1 | 10.7 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 1.1 | 2.1 | GO:0009822 | alkaloid catabolic process(GO:0009822) monoterpenoid metabolic process(GO:0016098) |
| 1.1 | 42.3 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 1.1 | 4.2 | GO:0035962 | response to interleukin-13(GO:0035962) |
| 1.0 | 5.2 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 1.0 | 5.2 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 1.0 | 6.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 1.0 | 4.1 | GO:0045906 | negative regulation of vasoconstriction(GO:0045906) |
| 1.0 | 6.2 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 1.0 | 4.1 | GO:1903631 | regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634) |
| 1.0 | 1.0 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 1.0 | 3.1 | GO:2000138 | positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
| 1.0 | 8.1 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 1.0 | 5.0 | GO:0048263 | determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263) |
| 1.0 | 11.1 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 1.0 | 11.0 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 1.0 | 1.0 | GO:1903412 | response to bile acid(GO:1903412) |
| 1.0 | 3.0 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
| 1.0 | 15.9 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) |
| 1.0 | 3.9 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 1.0 | 7.9 | GO:0042426 | choline catabolic process(GO:0042426) |
| 1.0 | 4.9 | GO:0042713 | sperm ejaculation(GO:0042713) |
| 1.0 | 4.9 | GO:0034344 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 1.0 | 5.7 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 1.0 | 5.7 | GO:0010533 | regulation of activation of Janus kinase activity(GO:0010533) |
| 1.0 | 6.7 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 0.9 | 3.8 | GO:1902283 | negative regulation of primary amine oxidase activity(GO:1902283) |
| 0.9 | 21.8 | GO:0036065 | fucosylation(GO:0036065) |
| 0.9 | 9.4 | GO:1900744 | regulation of p38MAPK cascade(GO:1900744) |
| 0.9 | 1.9 | GO:0098758 | response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) |
| 0.9 | 3.7 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.9 | 6.4 | GO:2000389 | regulation of neutrophil extravasation(GO:2000389) |
| 0.9 | 5.5 | GO:0072017 | distal tubule development(GO:0072017) |
| 0.9 | 17.5 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.9 | 5.5 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 0.9 | 3.6 | GO:0055062 | phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506) |
| 0.9 | 2.7 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of autophagosome maturation(GO:1901097) |
| 0.9 | 7.2 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 0.9 | 5.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.9 | 3.6 | GO:0032902 | nerve growth factor production(GO:0032902) |
| 0.9 | 22.3 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.9 | 19.5 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.9 | 15.1 | GO:0006000 | fructose metabolic process(GO:0006000) |
| 0.9 | 6.2 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.9 | 1.8 | GO:0009794 | regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448) |
| 0.9 | 4.4 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.9 | 17.6 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.9 | 5.3 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.9 | 12.2 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.9 | 1.7 | GO:1900118 | negative regulation of execution phase of apoptosis(GO:1900118) |
| 0.9 | 31.1 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.9 | 5.2 | GO:1902731 | negative regulation of chondrocyte proliferation(GO:1902731) |
| 0.9 | 6.0 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.9 | 2.6 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.8 | 2.5 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.8 | 38.1 | GO:0010518 | positive regulation of phospholipase activity(GO:0010518) |
| 0.8 | 5.1 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
| 0.8 | 2.5 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.8 | 0.8 | GO:1900450 | commissural neuron axon guidance(GO:0071679) negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782) |
| 0.8 | 4.2 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.8 | 1.7 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 0.8 | 3.4 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
| 0.8 | 4.2 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.8 | 2.5 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 0.8 | 3.3 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.8 | 5.0 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.8 | 10.8 | GO:0060605 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 0.8 | 23.6 | GO:0043616 | keratinocyte proliferation(GO:0043616) |
| 0.8 | 2.4 | GO:2001206 | positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206) |
| 0.8 | 4.8 | GO:0045348 | positive regulation of MHC class II biosynthetic process(GO:0045348) |
| 0.8 | 12.7 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.8 | 44.4 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.8 | 2.4 | GO:0034124 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) |
| 0.8 | 4.7 | GO:0042436 | tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) |
| 0.8 | 1.6 | GO:0001555 | oocyte growth(GO:0001555) |
| 0.8 | 5.5 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.8 | 2.3 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.8 | 25.7 | GO:0061028 | establishment of endothelial barrier(GO:0061028) |
| 0.8 | 17.9 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.8 | 9.3 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.8 | 7.7 | GO:0061000 | negative regulation of dendritic spine development(GO:0061000) |
| 0.8 | 5.4 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.8 | 2.3 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 0.8 | 12.2 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.8 | 2.3 | GO:0070091 | glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092) |
| 0.8 | 5.3 | GO:1902414 | protein localization to cell junction(GO:1902414) |
| 0.8 | 16.7 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
| 0.8 | 3.0 | GO:2000501 | regulation of natural killer cell chemotaxis(GO:2000501) |
| 0.8 | 8.3 | GO:0002347 | response to tumor cell(GO:0002347) |
| 0.8 | 3.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.7 | 1.5 | GO:0031630 | regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630) |
| 0.7 | 3.7 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.7 | 9.7 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.7 | 5.2 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.7 | 8.1 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.7 | 10.3 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.7 | 10.2 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 0.7 | 18.9 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.7 | 13.0 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.7 | 7.1 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
| 0.7 | 4.3 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.7 | 6.4 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.7 | 17.5 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.7 | 9.0 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.7 | 9.0 | GO:0006768 | biotin metabolic process(GO:0006768) |
| 0.7 | 8.8 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 0.7 | 4.1 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.7 | 38.0 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.7 | 5.3 | GO:0071073 | positive regulation of phospholipid biosynthetic process(GO:0071073) |
| 0.7 | 2.6 | GO:0034445 | regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) |
| 0.7 | 2.6 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.7 | 6.6 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 0.7 | 6.5 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.6 | 4.5 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.6 | 5.8 | GO:0003170 | heart valve development(GO:0003170) |
| 0.6 | 1.9 | GO:1904823 | pyrimidine nucleobase transport(GO:0015855) purine nucleoside transmembrane transport(GO:0015860) purine nucleobase transmembrane transport(GO:1904823) |
| 0.6 | 10.9 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.6 | 2.6 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.6 | 3.2 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 0.6 | 0.6 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.6 | 12.8 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.6 | 5.7 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.6 | 2.5 | GO:0048842 | positive regulation of axon extension involved in axon guidance(GO:0048842) |
| 0.6 | 5.1 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.6 | 9.5 | GO:2000194 | regulation of female gonad development(GO:2000194) |
| 0.6 | 3.8 | GO:0060453 | regulation of gastric acid secretion(GO:0060453) |
| 0.6 | 8.2 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.6 | 1.9 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.6 | 2.5 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
| 0.6 | 1.9 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 0.6 | 6.8 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.6 | 3.1 | GO:0009233 | menaquinone metabolic process(GO:0009233) |
| 0.6 | 0.6 | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
| 0.6 | 6.7 | GO:0019627 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
| 0.6 | 7.3 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.6 | 7.3 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.6 | 1.8 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.6 | 3.0 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.6 | 2.4 | GO:0098957 | anterograde axonal transport of mitochondrion(GO:0098957) |
| 0.6 | 0.6 | GO:1990791 | dorsal root ganglion development(GO:1990791) |
| 0.6 | 4.1 | GO:0002024 | diet induced thermogenesis(GO:0002024) |
| 0.6 | 4.1 | GO:0046852 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) bone trabecula formation(GO:0060346) |
| 0.6 | 4.7 | GO:0045066 | regulatory T cell differentiation(GO:0045066) regulation of regulatory T cell differentiation(GO:0045589) |
| 0.6 | 1.8 | GO:1990036 | regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) calcium ion import into sarcoplasmic reticulum(GO:1990036) |
| 0.6 | 1.7 | GO:0009624 | response to nematode(GO:0009624) |
| 0.6 | 2.9 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
| 0.6 | 15.5 | GO:0003197 | endocardial cushion development(GO:0003197) |
| 0.6 | 2.3 | GO:0030862 | positive regulation of polarized epithelial cell differentiation(GO:0030862) |
| 0.6 | 1.1 | GO:0021892 | cerebral cortex GABAergic interneuron differentiation(GO:0021892) |
| 0.6 | 4.5 | GO:0009880 | embryonic pattern specification(GO:0009880) |
| 0.6 | 6.2 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.6 | 3.9 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.6 | 8.3 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.6 | 5.0 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.6 | 2.8 | GO:0001575 | globoside metabolic process(GO:0001575) |
| 0.6 | 1.7 | GO:0003245 | growth involved in heart morphogenesis(GO:0003241) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 0.6 | 0.6 | GO:0033700 | phospholipid efflux(GO:0033700) |
| 0.5 | 1.1 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.5 | 3.8 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.5 | 5.5 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.5 | 6.6 | GO:0033687 | osteoblast proliferation(GO:0033687) |
| 0.5 | 12.0 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.5 | 2.2 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 0.5 | 2.7 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.5 | 9.2 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.5 | 6.5 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.5 | 12.4 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.5 | 5.4 | GO:0032740 | positive regulation of interleukin-17 production(GO:0032740) |
| 0.5 | 2.1 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
| 0.5 | 3.7 | GO:0043116 | negative regulation of vascular permeability(GO:0043116) |
| 0.5 | 2.1 | GO:0046102 | adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103) |
| 0.5 | 6.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.5 | 3.1 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
| 0.5 | 8.3 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.5 | 3.6 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.5 | 4.1 | GO:0015824 | proline transport(GO:0015824) |
| 0.5 | 1.0 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
| 0.5 | 1.0 | GO:0048840 | otolith development(GO:0048840) |
| 0.5 | 33.8 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.5 | 9.6 | GO:0071800 | podosome assembly(GO:0071800) |
| 0.5 | 4.5 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.5 | 3.0 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.5 | 1.5 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 0.5 | 9.5 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.5 | 3.0 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.5 | 2.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.5 | 12.2 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.5 | 5.4 | GO:0006552 | leucine metabolic process(GO:0006551) leucine catabolic process(GO:0006552) |
| 0.5 | 7.3 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.5 | 33.9 | GO:0070268 | cornification(GO:0070268) |
| 0.5 | 1.4 | GO:0019075 | virus maturation(GO:0019075) |
| 0.5 | 1.4 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.5 | 8.6 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.5 | 9.1 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.5 | 29.3 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.5 | 3.8 | GO:0051593 | response to folic acid(GO:0051593) |
| 0.5 | 4.2 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.5 | 9.4 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.5 | 11.8 | GO:0055090 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
| 0.5 | 7.9 | GO:0006555 | methionine metabolic process(GO:0006555) |
| 0.5 | 2.8 | GO:1901299 | negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299) |
| 0.5 | 1.4 | GO:1904640 | response to methionine(GO:1904640) |
| 0.5 | 3.2 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
| 0.5 | 5.6 | GO:0050927 | positive regulation of positive chemotaxis(GO:0050927) |
| 0.5 | 0.5 | GO:1904058 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) positive regulation of sensory perception of pain(GO:1904058) |
| 0.5 | 4.1 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.5 | 4.1 | GO:0006032 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.5 | 3.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.4 | 3.6 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.4 | 1.3 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.4 | 4.0 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.4 | 3.9 | GO:0060285 | cilium-dependent cell motility(GO:0060285) |
| 0.4 | 1.7 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.4 | 2.2 | GO:1904075 | bone mineralization involved in bone maturation(GO:0035630) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.4 | 1.3 | GO:0009730 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
| 0.4 | 3.0 | GO:0060973 | cell migration involved in heart development(GO:0060973) |
| 0.4 | 4.8 | GO:0097369 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.4 | 3.9 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.4 | 39.4 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.4 | 1.7 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 0.4 | 0.4 | GO:0086015 | SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070) |
| 0.4 | 3.0 | GO:0046710 | GDP metabolic process(GO:0046710) |
| 0.4 | 2.1 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.4 | 1.3 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.4 | 11.0 | GO:0032330 | regulation of chondrocyte differentiation(GO:0032330) |
| 0.4 | 2.1 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.4 | 6.3 | GO:0010996 | response to auditory stimulus(GO:0010996) |
| 0.4 | 5.8 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.4 | 2.5 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.4 | 2.9 | GO:0042711 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
| 0.4 | 10.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.4 | 5.3 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.4 | 5.3 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
| 0.4 | 2.0 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.4 | 8.5 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.4 | 0.8 | GO:0007431 | salivary gland development(GO:0007431) |
| 0.4 | 1.2 | GO:0002784 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803) |
| 0.4 | 3.6 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
| 0.4 | 9.9 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.4 | 6.6 | GO:0003299 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.4 | 3.1 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
| 0.4 | 1.6 | GO:0001696 | gastric acid secretion(GO:0001696) |
| 0.4 | 2.3 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.4 | 31.7 | GO:0035308 | negative regulation of protein dephosphorylation(GO:0035308) |
| 0.4 | 3.1 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.4 | 1.5 | GO:0097646 | dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.4 | 6.5 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.4 | 3.8 | GO:0097296 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296) |
| 0.4 | 8.0 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.4 | 0.8 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.4 | 1.1 | GO:0090230 | establishment of sister chromatid cohesion(GO:0034085) positive regulation of macrophage differentiation(GO:0045651) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of centromere complex assembly(GO:0090230) |
| 0.4 | 1.5 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.4 | 0.7 | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) |
| 0.4 | 6.6 | GO:0019835 | cytolysis(GO:0019835) |
| 0.4 | 16.0 | GO:0046849 | bone remodeling(GO:0046849) |
| 0.4 | 3.3 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.4 | 1.1 | GO:0035581 | sequestering of extracellular ligand from receptor(GO:0035581) |
| 0.4 | 16.7 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.4 | 6.5 | GO:0042036 | negative regulation of cytokine biosynthetic process(GO:0042036) |
| 0.4 | 3.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.4 | 10.0 | GO:0090311 | regulation of protein deacetylation(GO:0090311) |
| 0.4 | 1.8 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.4 | 2.8 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.4 | 6.4 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.4 | 2.5 | GO:0050482 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
| 0.3 | 21.3 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 0.3 | 2.1 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.3 | 0.7 | GO:0002876 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876) |
| 0.3 | 3.8 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.3 | 2.7 | GO:0007567 | parturition(GO:0007567) |
| 0.3 | 47.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.3 | 5.8 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.3 | 2.4 | GO:0048820 | hair follicle maturation(GO:0048820) |
| 0.3 | 11.1 | GO:0007422 | peripheral nervous system development(GO:0007422) |
| 0.3 | 4.7 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.3 | 1.0 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.3 | 3.7 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.3 | 9.3 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.3 | 3.9 | GO:2000111 | positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.3 | 3.0 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.3 | 0.3 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.3 | 0.9 | GO:1902462 | mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) regulation of mesenchymal stem cell differentiation(GO:2000739) positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.3 | 5.2 | GO:0001945 | lymph vessel development(GO:0001945) |
| 0.3 | 2.1 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 0.3 | 3.9 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.3 | 11.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.3 | 3.0 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.3 | 8.3 | GO:0032011 | ARF protein signal transduction(GO:0032011) |
| 0.3 | 166.6 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.3 | 7.6 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.3 | 0.9 | GO:0033605 | positive regulation of catecholamine secretion(GO:0033605) |
| 0.3 | 2.0 | GO:0002455 | humoral immune response mediated by circulating immunoglobulin(GO:0002455) |
| 0.3 | 4.6 | GO:0030593 | neutrophil chemotaxis(GO:0030593) |
| 0.3 | 0.9 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.3 | 0.9 | GO:0019934 | cGMP-mediated signaling(GO:0019934) |
| 0.3 | 2.3 | GO:0046463 | triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463) |
| 0.3 | 1.1 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.3 | 7.0 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.3 | 3.1 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.3 | 15.2 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.3 | 4.7 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.3 | 4.6 | GO:0010543 | regulation of platelet activation(GO:0010543) |
| 0.3 | 0.8 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.3 | 2.1 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 0.3 | 14.9 | GO:0042552 | myelination(GO:0042552) |
| 0.3 | 8.6 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.3 | 3.4 | GO:0021854 | hypothalamus development(GO:0021854) |
| 0.3 | 10.3 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.3 | 11.1 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.3 | 2.3 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.3 | 25.3 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.3 | 7.6 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.2 | 2.2 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.2 | 4.9 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.2 | 1.5 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.2 | 1.2 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.2 | 3.1 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
| 0.2 | 2.4 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.2 | 0.5 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.2 | 9.3 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.2 | 1.2 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.2 | 5.6 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
| 0.2 | 1.6 | GO:0015871 | choline transport(GO:0015871) |
| 0.2 | 4.9 | GO:1903169 | regulation of calcium ion transmembrane transport(GO:1903169) |
| 0.2 | 1.4 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.2 | 11.3 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.2 | 4.5 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.2 | 1.6 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 0.2 | 2.0 | GO:0030210 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.2 | 0.7 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
| 0.2 | 8.4 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.2 | 1.3 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.2 | 10.3 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.2 | 14.4 | GO:0007586 | digestion(GO:0007586) |
| 0.2 | 2.8 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.2 | 1.8 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.2 | 1.7 | GO:0034465 | urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848) response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794) |
| 0.2 | 0.8 | GO:0003416 | endochondral bone growth(GO:0003416) bone growth(GO:0098868) |
| 0.2 | 5.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.2 | 8.5 | GO:0019233 | sensory perception of pain(GO:0019233) |
| 0.2 | 2.8 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.2 | 1.1 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.2 | 0.2 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
| 0.2 | 6.3 | GO:1901998 | toxin transport(GO:1901998) |
| 0.2 | 2.2 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.2 | 4.0 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.2 | 1.6 | GO:0045714 | regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714) |
| 0.2 | 0.5 | GO:0061760 | antifungal innate immune response(GO:0061760) |
| 0.2 | 3.7 | GO:0014066 | regulation of phosphatidylinositol 3-kinase signaling(GO:0014066) |
| 0.2 | 1.4 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
| 0.2 | 2.0 | GO:0031018 | endocrine pancreas development(GO:0031018) |
| 0.2 | 0.5 | GO:0072387 | flavin adenine dinucleotide metabolic process(GO:0072387) |
| 0.2 | 1.9 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 2.0 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.2 | 2.3 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.2 | 1.0 | GO:0034311 | sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311) |
| 0.2 | 1.3 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.2 | 1.4 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.2 | 1.9 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.2 | 0.5 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.2 | 2.3 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.2 | 0.3 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.2 | 2.2 | GO:1902221 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.2 | 4.0 | GO:0006693 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.2 | 2.9 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.2 | 1.8 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.2 | 1.5 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.1 | 2.5 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.1 | 0.7 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 4.2 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.1 | 4.5 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.1 | 0.6 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.1 | 7.2 | GO:0018210 | peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210) |
| 0.1 | 1.6 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.1 | 2.5 | GO:0015838 | amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879) |
| 0.1 | 2.7 | GO:0031640 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.1 | 2.0 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 0.9 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.1 | 0.3 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.1 | 0.5 | GO:0016048 | detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951) |
| 0.1 | 6.6 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.1 | 3.6 | GO:0010803 | regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803) |
| 0.1 | 0.5 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.1 | 7.6 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
| 0.1 | 2.0 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.1 | 3.8 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.1 | 0.7 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.1 | 1.3 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 2.9 | GO:0009798 | axis specification(GO:0009798) |
| 0.1 | 0.4 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.1 | 1.0 | GO:0071380 | cellular response to prostaglandin E stimulus(GO:0071380) |
| 0.1 | 0.8 | GO:0051282 | release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283) |
| 0.1 | 0.5 | GO:0097396 | response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398) |
| 0.1 | 1.1 | GO:0042554 | superoxide anion generation(GO:0042554) |
| 0.1 | 1.5 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.1 | 0.9 | GO:0032094 | response to food(GO:0032094) |
| 0.1 | 0.5 | GO:0009593 | detection of chemical stimulus(GO:0009593) |
| 0.1 | 1.2 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.1 | 1.1 | GO:0042772 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772) |
| 0.1 | 1.8 | GO:0030888 | regulation of B cell proliferation(GO:0030888) |
| 0.1 | 5.8 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.1 | 0.4 | GO:0060992 | response to fungicide(GO:0060992) |
| 0.1 | 0.4 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 1.0 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.1 | 1.0 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393) |
| 0.1 | 2.5 | GO:0030166 | proteoglycan biosynthetic process(GO:0030166) |
| 0.1 | 2.1 | GO:0061641 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.1 | 0.5 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.1 | 1.4 | GO:1903557 | positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557) |
| 0.1 | 1.0 | GO:0007606 | sensory perception of chemical stimulus(GO:0007606) |
| 0.1 | 0.5 | GO:0015884 | folic acid transport(GO:0015884) |
| 0.0 | 0.1 | GO:0043323 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.0 | 0.3 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 0.0 | 0.2 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.0 | 0.2 | GO:0035791 | platelet-derived growth factor receptor-beta signaling pathway(GO:0035791) |
| 0.0 | 0.8 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 1.5 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.2 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.0 | 2.0 | GO:0009566 | fertilization(GO:0009566) |
| 0.0 | 0.1 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.0 | 0.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.9 | GO:0021510 | spinal cord development(GO:0021510) |
| 0.0 | 2.3 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 0.4 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 0.0 | GO:0006258 | UDP-glucose catabolic process(GO:0006258) |
| 0.0 | 0.1 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 0.3 | GO:0045667 | regulation of osteoblast differentiation(GO:0045667) |
| 0.0 | 0.2 | GO:0032456 | endocytic recycling(GO:0032456) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 30.2 | 242.0 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 15.2 | 60.9 | GO:0070695 | FHF complex(GO:0070695) |
| 7.6 | 60.7 | GO:0035976 | AP1 complex(GO:0035976) |
| 7.0 | 28.1 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 6.6 | 223.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 6.3 | 25.0 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 5.4 | 21.4 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 5.2 | 15.7 | GO:0044609 | DBIRD complex(GO:0044609) |
| 4.3 | 13.0 | GO:0070701 | mucus layer(GO:0070701) |
| 4.3 | 47.3 | GO:0043203 | axon hillock(GO:0043203) |
| 4.0 | 119.2 | GO:0030057 | desmosome(GO:0030057) |
| 4.0 | 23.8 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 3.9 | 11.7 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 3.7 | 11.2 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 3.5 | 10.6 | GO:0071756 | IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756) |
| 3.3 | 9.8 | GO:0043259 | laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
| 3.0 | 9.0 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 2.9 | 11.8 | GO:0002139 | stereocilia coupling link(GO:0002139) |
| 2.8 | 19.3 | GO:0044279 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 2.8 | 8.3 | GO:0097229 | sperm end piece(GO:0097229) |
| 2.6 | 34.4 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 2.6 | 13.2 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 2.6 | 15.6 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 2.6 | 7.7 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 2.6 | 10.3 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 2.5 | 12.7 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 2.5 | 5.0 | GO:0097449 | astrocyte projection(GO:0097449) |
| 2.4 | 17.1 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 2.4 | 7.3 | GO:0043293 | apoptosome(GO:0043293) |
| 2.3 | 57.7 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 2.3 | 6.9 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 2.3 | 18.3 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 2.2 | 11.2 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 2.2 | 4.5 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 2.2 | 26.4 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 2.2 | 10.9 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 2.1 | 17.1 | GO:0043256 | laminin complex(GO:0043256) |
| 2.1 | 6.4 | GO:0032116 | SMC loading complex(GO:0032116) |
| 2.1 | 23.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 2.1 | 8.2 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 2.0 | 20.1 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 2.0 | 6.0 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 2.0 | 11.8 | GO:0045298 | tubulin complex(GO:0045298) |
| 2.0 | 3.9 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 2.0 | 9.8 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 1.9 | 5.8 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 1.9 | 13.6 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 1.9 | 9.6 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 1.8 | 12.7 | GO:1990130 | Iml1 complex(GO:1990130) |
| 1.8 | 7.0 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 1.7 | 140.0 | GO:0034707 | chloride channel complex(GO:0034707) |
| 1.6 | 4.9 | GO:0099569 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 1.6 | 14.5 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 1.6 | 3.2 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 1.6 | 23.7 | GO:0033010 | paranodal junction(GO:0033010) |
| 1.6 | 6.3 | GO:0071942 | XPC complex(GO:0071942) |
| 1.5 | 9.2 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 1.5 | 31.6 | GO:0005604 | basement membrane(GO:0005604) |
| 1.5 | 46.4 | GO:0034706 | sodium channel complex(GO:0034706) |
| 1.5 | 28.2 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 1.5 | 16.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 1.5 | 23.4 | GO:0016600 | flotillin complex(GO:0016600) |
| 1.4 | 4.3 | GO:0005592 | collagen type XI trimer(GO:0005592) |
| 1.4 | 20.0 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 1.4 | 25.6 | GO:0005922 | connexon complex(GO:0005922) |
| 1.4 | 55.1 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 1.4 | 35.1 | GO:0001533 | cornified envelope(GO:0001533) |
| 1.4 | 2.7 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 1.3 | 14.7 | GO:0097427 | microtubule bundle(GO:0097427) |
| 1.3 | 13.3 | GO:0044194 | cytolytic granule(GO:0044194) |
| 1.3 | 4.0 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 1.3 | 6.6 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 1.3 | 9.1 | GO:1990745 | EARP complex(GO:1990745) |
| 1.3 | 20.4 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 1.3 | 7.5 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 1.2 | 16.2 | GO:0043083 | synaptic cleft(GO:0043083) |
| 1.2 | 49.3 | GO:0045095 | keratin filament(GO:0045095) |
| 1.2 | 6.1 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 1.2 | 12.2 | GO:0033270 | paranode region of axon(GO:0033270) |
| 1.2 | 4.7 | GO:0034681 | integrin alpha11-beta1 complex(GO:0034681) |
| 1.2 | 15.3 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 1.2 | 32.9 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 1.2 | 4.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 1.2 | 18.4 | GO:0001741 | XY body(GO:0001741) |
| 1.1 | 10.3 | GO:0045180 | basal cortex(GO:0045180) |
| 1.1 | 2.3 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 1.1 | 7.9 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 1.1 | 5.3 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 1.0 | 12.5 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 1.0 | 20.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 1.0 | 5.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 1.0 | 26.4 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 1.0 | 113.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.9 | 10.3 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 0.9 | 46.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.9 | 12.9 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.9 | 9.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.9 | 4.6 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.9 | 19.2 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.9 | 18.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.9 | 1.8 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.9 | 4.4 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.9 | 8.8 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.9 | 6.2 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.9 | 10.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.9 | 2.6 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 0.8 | 8.4 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.8 | 4.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.8 | 9.1 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.8 | 38.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.8 | 9.9 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.8 | 10.7 | GO:0005902 | microvillus(GO:0005902) |
| 0.8 | 52.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.8 | 2.3 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.8 | 11.7 | GO:0097433 | dense body(GO:0097433) |
| 0.8 | 4.6 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.8 | 13.9 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.8 | 2.3 | GO:0071546 | pi-body(GO:0071546) |
| 0.8 | 21.3 | GO:0043235 | receptor complex(GO:0043235) |
| 0.8 | 8.3 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.8 | 3.0 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.8 | 5.3 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.7 | 5.2 | GO:0098845 | postsynaptic endosome(GO:0098845) |
| 0.7 | 5.2 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.7 | 78.3 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.7 | 3.6 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.7 | 2.1 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.7 | 6.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.7 | 8.4 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.7 | 2.1 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.7 | 15.9 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.7 | 13.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.7 | 4.8 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.7 | 14.9 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.7 | 27.3 | GO:0016592 | mediator complex(GO:0016592) |
| 0.7 | 7.3 | GO:0005883 | neurofilament(GO:0005883) |
| 0.7 | 3.3 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.7 | 6.5 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.6 | 2.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.6 | 21.0 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.6 | 174.0 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.6 | 2.5 | GO:0097123 | cyclin A1-CDK2 complex(GO:0097123) |
| 0.6 | 1.8 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.6 | 8.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.6 | 3.0 | GO:0089701 | U2AF(GO:0089701) |
| 0.6 | 4.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.6 | 8.9 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.6 | 11.1 | GO:0044447 | axoneme part(GO:0044447) |
| 0.6 | 4.0 | GO:0035859 | Seh1-associated complex(GO:0035859) |
| 0.6 | 4.0 | GO:0005921 | gap junction(GO:0005921) |
| 0.6 | 4.0 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.6 | 6.2 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.6 | 16.1 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.6 | 1.7 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.5 | 3.2 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.5 | 3.2 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.5 | 6.3 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.5 | 2.6 | GO:0045179 | apical cortex(GO:0045179) |
| 0.5 | 67.6 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.5 | 25.2 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.5 | 3.6 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.5 | 17.5 | GO:0000791 | euchromatin(GO:0000791) |
| 0.5 | 7.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.5 | 2.5 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 0.5 | 3.4 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.5 | 3.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.5 | 1.4 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.5 | 1.9 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 0.5 | 18.3 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.5 | 8.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.5 | 13.0 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.5 | 4.6 | GO:0005605 | basal lamina(GO:0005605) |
| 0.4 | 661.4 | GO:0005615 | extracellular space(GO:0005615) |
| 0.4 | 2.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.4 | 19.9 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.4 | 22.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.4 | 6.0 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.4 | 7.6 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.4 | 12.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.4 | 10.2 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.4 | 2.4 | GO:0000243 | commitment complex(GO:0000243) |
| 0.4 | 1.5 | GO:0038038 | G-protein coupled receptor homodimeric complex(GO:0038038) |
| 0.4 | 7.9 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.4 | 3.6 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.4 | 23.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.3 | 5.2 | GO:0046930 | pore complex(GO:0046930) |
| 0.3 | 13.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.3 | 43.0 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.3 | 14.7 | GO:0031672 | A band(GO:0031672) |
| 0.3 | 5.5 | GO:0005901 | caveola(GO:0005901) |
| 0.3 | 2.0 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.3 | 29.5 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.3 | 4.0 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.3 | 29.4 | GO:0030018 | Z disc(GO:0030018) |
| 0.3 | 7.3 | GO:0008328 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
| 0.3 | 11.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.3 | 22.6 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.3 | 1.1 | GO:0035363 | histone locus body(GO:0035363) |
| 0.3 | 1.5 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.2 | 3.9 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.2 | 2.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.2 | 0.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.2 | 19.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.2 | 3.3 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.2 | 1.5 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.2 | 2.3 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.2 | 1.8 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.2 | 1.2 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.2 | 0.6 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.2 | 1.0 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.2 | 3.7 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.2 | 0.7 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.2 | 1.1 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.2 | 1.1 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.2 | 1.9 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.2 | 3.1 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.2 | 9.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.2 | 5.8 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.1 | 20.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 1.0 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 1.1 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 7.7 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 1.7 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 0.5 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.1 | 2.6 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.1 | 14.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 0.3 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 362.7 | GO:0031224 | intrinsic component of membrane(GO:0031224) |
| 0.1 | 5.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 12.6 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 1.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 2.0 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 0.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 13.4 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.1 | 1.1 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.1 | 0.3 | GO:0032449 | CBM complex(GO:0032449) |
| 0.1 | 0.9 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.0 | 0.9 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 0.2 | GO:0098576 | lumenal side of membrane(GO:0098576) |
| 0.0 | 0.8 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.2 | GO:0033061 | DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 0.3 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 1.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 14.1 | 113.1 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 10.6 | 42.5 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 9.5 | 28.6 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 8.3 | 33.2 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 6.2 | 18.7 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
| 5.9 | 29.3 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 5.7 | 22.9 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
| 5.3 | 26.7 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 5.1 | 20.5 | GO:0032560 | dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567) |
| 5.0 | 20.0 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 4.8 | 19.2 | GO:0004078 | biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271) |
| 4.6 | 18.5 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 4.4 | 13.2 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 4.3 | 12.9 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 4.2 | 54.2 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 4.2 | 12.5 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 4.1 | 16.4 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 4.0 | 36.4 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 4.0 | 56.5 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 4.0 | 20.1 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 3.9 | 11.7 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 3.8 | 15.3 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
| 3.8 | 11.4 | GO:0033749 | histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749) |
| 3.8 | 11.3 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 3.7 | 11.0 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 3.7 | 18.3 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 3.6 | 14.3 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 3.4 | 40.5 | GO:0038132 | neuregulin binding(GO:0038132) |
| 3.4 | 16.9 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 3.2 | 22.5 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 3.1 | 18.8 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 3.1 | 15.4 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 3.0 | 9.0 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 3.0 | 14.8 | GO:1990254 | keratin filament binding(GO:1990254) |
| 3.0 | 11.8 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 2.9 | 11.5 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 2.9 | 8.6 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 2.9 | 11.5 | GO:0050262 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 2.8 | 11.3 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 2.8 | 8.3 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 2.8 | 5.5 | GO:0038064 | collagen receptor activity(GO:0038064) |
| 2.8 | 11.1 | GO:0031716 | calcitonin receptor binding(GO:0031716) |
| 2.8 | 5.5 | GO:0070888 | E-box binding(GO:0070888) |
| 2.8 | 27.6 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 2.7 | 16.5 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 2.7 | 24.7 | GO:0043426 | MRF binding(GO:0043426) |
| 2.7 | 10.8 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 2.7 | 24.0 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 2.6 | 10.4 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 2.6 | 38.8 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 2.6 | 18.0 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
| 2.6 | 7.7 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 2.5 | 7.6 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 2.5 | 5.1 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 2.5 | 15.1 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 2.5 | 9.9 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 2.5 | 7.4 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 2.4 | 7.3 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 2.4 | 7.2 | GO:0070052 | collagen V binding(GO:0070052) |
| 2.4 | 16.7 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 2.4 | 7.1 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 2.4 | 66.5 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 2.4 | 14.2 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 2.3 | 7.0 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 2.3 | 11.7 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 2.3 | 20.7 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 2.3 | 16.1 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 2.3 | 6.9 | GO:0086059 | voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059) |
| 2.3 | 6.9 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 2.3 | 9.1 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 2.3 | 6.8 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 2.3 | 34.1 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 2.3 | 9.0 | GO:0047708 | biotinidase activity(GO:0047708) |
| 2.3 | 6.8 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 2.3 | 9.0 | GO:0086020 | gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
| 2.2 | 11.2 | GO:0045174 | glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 2.2 | 6.7 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 2.2 | 6.7 | GO:0047783 | steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783) |
| 2.1 | 6.4 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 2.1 | 12.6 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 2.1 | 6.3 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 2.1 | 8.3 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 2.1 | 12.3 | GO:0016416 | O-palmitoyltransferase activity(GO:0016416) |
| 2.0 | 6.0 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 2.0 | 10.0 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 2.0 | 11.9 | GO:0034046 | poly(G) binding(GO:0034046) |
| 2.0 | 13.7 | GO:0031705 | bombesin receptor binding(GO:0031705) |
| 2.0 | 27.4 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 2.0 | 7.8 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 1.9 | 17.3 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 1.9 | 26.8 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 1.9 | 5.6 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 1.9 | 16.7 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 1.9 | 5.6 | GO:0052853 | (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854) |
| 1.9 | 7.4 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 1.8 | 14.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 1.8 | 11.0 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 1.8 | 21.8 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
| 1.8 | 56.2 | GO:0030506 | ankyrin binding(GO:0030506) |
| 1.8 | 14.5 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 1.8 | 9.0 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 1.8 | 19.7 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 1.8 | 7.1 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 1.8 | 8.8 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 1.8 | 5.3 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 1.7 | 10.4 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 1.7 | 48.5 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 1.7 | 5.2 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 1.7 | 37.2 | GO:0043121 | neurotrophin binding(GO:0043121) |
| 1.7 | 21.9 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 1.7 | 13.5 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 1.7 | 8.4 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 1.7 | 11.6 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 1.6 | 8.2 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 1.6 | 6.6 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 1.6 | 4.9 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 1.6 | 11.4 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 1.6 | 13.0 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 1.6 | 4.9 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 1.6 | 16.2 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 1.6 | 42.0 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 1.6 | 9.6 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 1.6 | 23.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 1.6 | 14.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 1.6 | 6.3 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 1.6 | 53.2 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 1.6 | 12.5 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 1.6 | 4.7 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 1.5 | 7.7 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 1.5 | 9.3 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 1.5 | 23.1 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 1.5 | 4.6 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 1.5 | 10.7 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 1.5 | 4.6 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 1.5 | 7.6 | GO:1903136 | cuprous ion binding(GO:1903136) |
| 1.5 | 4.6 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
| 1.5 | 175.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 1.5 | 7.5 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
| 1.5 | 6.0 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 1.5 | 13.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 1.5 | 1.5 | GO:0015464 | acetylcholine receptor activity(GO:0015464) |
| 1.5 | 23.5 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 1.5 | 1.5 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 1.5 | 11.7 | GO:0008430 | selenium binding(GO:0008430) |
| 1.5 | 10.2 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 1.5 | 7.3 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 1.4 | 24.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 1.4 | 1.4 | GO:0052739 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 1.4 | 19.8 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 1.4 | 5.6 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 1.4 | 5.5 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 1.4 | 140.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 1.3 | 9.4 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 1.3 | 5.4 | GO:0061513 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 1.3 | 28.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 1.3 | 24.1 | GO:0070513 | death domain binding(GO:0070513) |
| 1.3 | 16.0 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 1.3 | 7.9 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 1.3 | 3.9 | GO:0036054 | protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697) |
| 1.3 | 7.9 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 1.3 | 20.8 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 1.3 | 5.2 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 1.3 | 6.4 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 1.3 | 20.5 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 1.3 | 3.8 | GO:0004961 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 1.3 | 39.4 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 1.3 | 12.7 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 1.3 | 102.9 | GO:0005254 | chloride channel activity(GO:0005254) |
| 1.3 | 3.8 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 1.3 | 356.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 1.2 | 7.5 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 1.2 | 4.9 | GO:0031893 | vasopressin receptor binding(GO:0031893) |
| 1.2 | 3.7 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 1.2 | 11.0 | GO:0048495 | Roundabout binding(GO:0048495) |
| 1.2 | 27.0 | GO:0022829 | wide pore channel activity(GO:0022829) |
| 1.2 | 7.3 | GO:0005330 | dopamine:sodium symporter activity(GO:0005330) |
| 1.2 | 8.5 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 1.2 | 34.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 1.2 | 4.8 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) |
| 1.2 | 10.9 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 1.2 | 3.6 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 1.2 | 4.7 | GO:0047804 | cysteine-S-conjugate beta-lyase activity(GO:0047804) |
| 1.2 | 4.7 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 1.2 | 7.0 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 1.2 | 80.6 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 1.2 | 5.8 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 1.2 | 17.4 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 1.2 | 35.9 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 1.2 | 6.9 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 1.1 | 14.9 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 1.1 | 4.5 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 1.1 | 9.1 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 1.1 | 4.5 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 1.1 | 2.3 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 1.1 | 5.7 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 1.1 | 7.8 | GO:0030250 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 1.1 | 8.9 | GO:0045159 | myosin II binding(GO:0045159) |
| 1.1 | 50.0 | GO:0042379 | chemokine receptor binding(GO:0042379) |
| 1.1 | 6.7 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 1.1 | 14.3 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 1.1 | 13.0 | GO:0016594 | glycine binding(GO:0016594) |
| 1.1 | 4.3 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
| 1.1 | 4.3 | GO:0010857 | calcium-dependent protein kinase activity(GO:0010857) |
| 1.1 | 6.4 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 1.1 | 6.3 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 1.0 | 5.2 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 1.0 | 4.1 | GO:0004341 | gluconolactonase activity(GO:0004341) |
| 1.0 | 10.2 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 1.0 | 8.2 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 1.0 | 8.0 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 1.0 | 6.0 | GO:0003680 | AT DNA binding(GO:0003680) |
| 1.0 | 3.0 | GO:0061609 | fructose-1-phosphate aldolase activity(GO:0061609) |
| 1.0 | 14.9 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 1.0 | 4.9 | GO:0050436 | microfibril binding(GO:0050436) |
| 1.0 | 1.0 | GO:0047756 | chondroitin 4-sulfotransferase activity(GO:0047756) |
| 1.0 | 116.0 | GO:0005179 | hormone activity(GO:0005179) |
| 1.0 | 3.9 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 1.0 | 9.8 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 1.0 | 8.8 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 1.0 | 2.9 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 1.0 | 5.8 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 1.0 | 8.6 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 1.0 | 23.9 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.9 | 12.2 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.9 | 3.7 | GO:0015056 | corticotrophin-releasing factor receptor activity(GO:0015056) |
| 0.9 | 1.9 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 0.9 | 4.6 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.9 | 29.6 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
| 0.9 | 9.2 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.9 | 5.5 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.9 | 3.6 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.9 | 2.7 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.9 | 6.3 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.9 | 18.8 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.9 | 2.7 | GO:0071253 | connexin binding(GO:0071253) |
| 0.9 | 34.9 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.9 | 5.3 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.9 | 22.3 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.9 | 6.2 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.9 | 22.8 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.9 | 0.9 | GO:0031755 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 0.9 | 14.8 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.9 | 6.1 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.9 | 7.8 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.9 | 5.2 | GO:0016807 | cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) |
| 0.9 | 12.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.9 | 6.9 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 0.9 | 0.9 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
| 0.9 | 11.1 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.8 | 2.5 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.8 | 6.7 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.8 | 5.8 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.8 | 15.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.8 | 10.0 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.8 | 5.0 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.8 | 11.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.8 | 2.4 | GO:0031711 | bradykinin receptor binding(GO:0031711) |
| 0.8 | 20.0 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.8 | 3.2 | GO:0004031 | aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) |
| 0.8 | 7.0 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.8 | 3.9 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.8 | 21.0 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.8 | 2.3 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.8 | 6.2 | GO:0097027 | phosphothreonine binding(GO:0050816) ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.8 | 6.9 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.8 | 0.8 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.8 | 1.5 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.8 | 4.6 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.8 | 1.5 | GO:0042165 | neurotransmitter binding(GO:0042165) |
| 0.8 | 18.3 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.8 | 9.1 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.8 | 20.5 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.8 | 2.3 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.8 | 3.0 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.8 | 15.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.7 | 8.9 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.7 | 3.0 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.7 | 3.7 | GO:0052656 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.7 | 14.7 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.7 | 20.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.7 | 5.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.7 | 6.4 | GO:1901611 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
| 0.7 | 7.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.7 | 1.4 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.7 | 4.2 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.7 | 6.2 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.7 | 6.2 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.7 | 11.7 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.7 | 4.1 | GO:0005221 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.7 | 1.4 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.7 | 12.1 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.7 | 18.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.7 | 2.0 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.7 | 8.6 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.7 | 17.1 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.6 | 1.9 | GO:0005350 | pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389) |
| 0.6 | 1.3 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 0.6 | 16.0 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.6 | 13.4 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.6 | 6.9 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.6 | 4.4 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.6 | 2.5 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 0.6 | 10.0 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.6 | 5.0 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.6 | 2.5 | GO:0051734 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.6 | 3.1 | GO:0004905 | type I interferon receptor activity(GO:0004905) |
| 0.6 | 6.2 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.6 | 13.2 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.6 | 20.7 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.6 | 5.9 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.6 | 26.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.6 | 6.9 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.6 | 15.0 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.6 | 20.7 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.6 | 2.8 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.6 | 2.3 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.6 | 1.1 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.6 | 8.4 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.6 | 16.1 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.6 | 0.6 | GO:0034040 | lipid-transporting ATPase activity(GO:0034040) |
| 0.5 | 14.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.5 | 3.8 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 0.5 | 8.7 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 0.5 | 2.7 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.5 | 2.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.5 | 6.4 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.5 | 4.8 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.5 | 46.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.5 | 3.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.5 | 5.1 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.5 | 6.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.5 | 25.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.5 | 4.5 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.5 | 7.0 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.5 | 2.5 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.5 | 3.5 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.5 | 1.5 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.5 | 3.4 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.5 | 4.4 | GO:0046870 | cadmium ion binding(GO:0046870) |
| 0.5 | 2.9 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.5 | 4.8 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.5 | 7.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.5 | 2.8 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.5 | 4.7 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.5 | 2.7 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.5 | 1.8 | GO:0070404 | NADH binding(GO:0070404) |
| 0.4 | 1.8 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.4 | 12.0 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.4 | 9.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.4 | 7.1 | GO:0005537 | mannose binding(GO:0005537) |
| 0.4 | 2.6 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.4 | 4.8 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.4 | 2.6 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.4 | 6.4 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.4 | 13.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.4 | 1.3 | GO:0071566 | UFM1 activating enzyme activity(GO:0071566) |
| 0.4 | 27.5 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.4 | 1.6 | GO:0019863 | IgE binding(GO:0019863) |
| 0.4 | 18.0 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.4 | 2.8 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.4 | 8.7 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.4 | 5.5 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.4 | 4.7 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.4 | 2.7 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.4 | 9.7 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
| 0.4 | 1.2 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.4 | 8.1 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.4 | 4.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.4 | 1.1 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.4 | 4.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.4 | 7.9 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.4 | 5.3 | GO:1901567 | icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
| 0.4 | 3.0 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.4 | 2.6 | GO:0016723 | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
| 0.4 | 6.7 | GO:0005112 | Notch binding(GO:0005112) |
| 0.4 | 13.3 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.4 | 2.6 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.4 | 1.8 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
| 0.4 | 15.7 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.4 | 14.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.4 | 97.7 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.4 | 1.8 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.4 | 9.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.4 | 4.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.4 | 10.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.4 | 10.9 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.3 | 9.9 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.3 | 2.0 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.3 | 27.6 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.3 | 5.0 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.3 | 5.0 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.3 | 8.8 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.3 | 1.0 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.3 | 4.5 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.3 | 7.3 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.3 | 3.4 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.3 | 2.8 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.3 | 1.8 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.3 | 0.6 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
| 0.3 | 2.4 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.3 | 9.1 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.3 | 14.3 | GO:0017022 | myosin binding(GO:0017022) |
| 0.3 | 50.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.3 | 15.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.3 | 4.6 | GO:0016849 | phosphorus-oxygen lyase activity(GO:0016849) |
| 0.3 | 37.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.3 | 1.4 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.3 | 0.8 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.3 | 1.4 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.3 | 1.9 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.3 | 1.6 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.3 | 2.2 | GO:0004996 | thyroid-stimulating hormone receptor activity(GO:0004996) |
| 0.3 | 1.9 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.3 | 6.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.3 | 2.1 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.3 | 5.0 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.3 | 0.8 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.3 | 2.0 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.3 | 25.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 1.0 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.2 | 7.0 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.2 | 2.2 | GO:0022840 | leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842) |
| 0.2 | 2.2 | GO:0003720 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.2 | 3.0 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.2 | 5.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.2 | 14.8 | GO:0020037 | heme binding(GO:0020037) |
| 0.2 | 0.5 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.2 | 2.6 | GO:0019864 | IgG binding(GO:0019864) |
| 0.2 | 2.8 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.2 | 3.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.2 | 4.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.2 | 11.5 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.2 | 2.0 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.2 | 1.3 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.2 | 0.7 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.2 | 1.1 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.2 | 10.9 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.2 | 2.1 | GO:0005217 | intracellular ligand-gated ion channel activity(GO:0005217) calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
| 0.2 | 6.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.2 | 1.6 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.2 | 2.0 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.2 | 3.2 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.2 | 19.1 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.2 | 2.0 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.2 | 6.3 | GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645) |
| 0.2 | 1.5 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.2 | 0.8 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.2 | 0.6 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.2 | 4.2 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
| 0.2 | 0.9 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.2 | 1.8 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.2 | 2.8 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.2 | 0.7 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.2 | 2.6 | GO:0001848 | complement binding(GO:0001848) |
| 0.2 | 1.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.2 | 0.5 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.2 | 1.2 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.2 | 2.0 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.2 | 0.8 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 0.2 | 36.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.2 | 3.5 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.2 | 0.5 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.2 | 4.0 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.2 | 0.6 | GO:0004102 | choline O-acetyltransferase activity(GO:0004102) |
| 0.1 | 1.4 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.1 | 1.3 | GO:0008061 | chitinase activity(GO:0004568) chitin binding(GO:0008061) |
| 0.1 | 0.3 | GO:0016532 | superoxide dismutase copper chaperone activity(GO:0016532) |
| 0.1 | 1.0 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 1.0 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.1 | 1.0 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.1 | 4.0 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.1 | 3.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 3.2 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.1 | 0.8 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 2.7 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 4.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 109.6 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.1 | 2.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 0.4 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 0.1 | 21.3 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.1 | 0.8 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 0.4 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.1 | 0.2 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 0.5 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.1 | 0.2 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.1 | 0.4 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.1 | 0.6 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 2.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 0.5 | GO:0043813 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 0.1 | 1.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 0.8 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 0.4 | GO:0052834 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.0 | 0.5 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 2.3 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
| 0.0 | 0.6 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.0 | 0.5 | GO:0016502 | purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) |
| 0.0 | 0.5 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 0.5 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.0 | 0.1 | GO:0047325 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 0.0 | 0.5 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.1 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.1 | GO:0031014 | troponin T binding(GO:0031014) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 52.1 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 2.3 | 50.5 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 2.3 | 6.8 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 1.9 | 1.9 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 1.8 | 5.5 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 1.8 | 74.9 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 1.8 | 18.2 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 1.6 | 27.3 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 1.3 | 15.9 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 1.3 | 31.0 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 1.2 | 43.3 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 1.2 | 38.7 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 1.2 | 19.8 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 1.2 | 37.1 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 1.2 | 58.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 1.1 | 52.8 | NABA COLLAGENS | Genes encoding collagen proteins |
| 1.1 | 35.0 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 1.1 | 83.3 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 1.0 | 10.8 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.9 | 25.2 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.9 | 11.0 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.9 | 8.1 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.9 | 27.2 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.8 | 49.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.8 | 12.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.8 | 4.0 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.8 | 3.2 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.8 | 273.1 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.7 | 12.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.7 | 17.0 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.7 | 28.0 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.7 | 10.4 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.7 | 22.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.6 | 11.8 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.6 | 103.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.6 | 14.8 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.6 | 7.7 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.6 | 17.5 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.6 | 39.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.6 | 7.2 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.5 | 29.1 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.5 | 5.6 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.5 | 6.0 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.5 | 5.0 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.5 | 5.9 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.5 | 21.8 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.5 | 6.2 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.5 | 20.8 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.5 | 16.0 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.5 | 10.7 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.5 | 15.8 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.5 | 23.6 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.4 | 2.6 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.4 | 0.8 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.4 | 16.5 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.4 | 7.8 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.4 | 16.2 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.4 | 5.0 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.4 | 21.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.3 | 10.2 | PID FGF PATHWAY | FGF signaling pathway |
| 0.3 | 7.8 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.3 | 1.9 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.3 | 6.4 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.3 | 10.0 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.3 | 4.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.3 | 13.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.3 | 1.7 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.3 | 5.1 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.3 | 52.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.2 | 11.5 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.2 | 2.0 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.2 | 2.0 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.2 | 3.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.2 | 3.1 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.2 | 2.0 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.2 | 3.7 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.2 | 2.2 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.2 | 10.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 2.5 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 1.9 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.1 | 1.8 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 4.0 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 2.1 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 10.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 6.4 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 5.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 3.0 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 3.5 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.1 | 2.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 0.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 1.5 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 8.4 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 0.5 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 1.4 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.1 | 1.2 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 0.6 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.1 | 3.2 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.1 | 1.0 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 0.5 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.2 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.4 | 96.2 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 4.2 | 164.6 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 2.4 | 84.3 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 2.3 | 63.0 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 2.3 | 25.6 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 2.2 | 88.5 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 2.0 | 16.3 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 1.8 | 46.1 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 1.8 | 45.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 1.8 | 12.6 | REACTOME PERK REGULATED GENE EXPRESSION | Genes involved in PERK regulated gene expression |
| 1.7 | 35.8 | REACTOME DEFENSINS | Genes involved in Defensins |
| 1.6 | 18.6 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 1.5 | 63.9 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 1.4 | 25.6 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 1.4 | 30.7 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 1.4 | 19.5 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 1.4 | 16.4 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 1.3 | 9.3 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 1.3 | 26.0 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 1.3 | 23.4 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 1.3 | 9.0 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 1.3 | 13.8 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 1.2 | 23.6 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 1.2 | 14.3 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 1.2 | 44.6 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 1.1 | 40.0 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 1.1 | 24.9 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 1.1 | 33.2 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 1.0 | 30.5 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 1.0 | 3.8 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.9 | 45.6 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.9 | 13.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.9 | 23.6 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.9 | 19.8 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.9 | 11.3 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.9 | 21.0 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.9 | 64.5 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.9 | 19.1 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.9 | 109.7 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.9 | 8.8 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.9 | 8.5 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.9 | 7.7 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.8 | 12.7 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.8 | 15.9 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.8 | 49.2 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.8 | 13.4 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.8 | 10.2 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.8 | 41.3 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.8 | 12.1 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.7 | 6.7 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.7 | 9.5 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.7 | 15.3 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.7 | 1.4 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.7 | 18.1 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.7 | 15.8 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.7 | 24.8 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.7 | 24.7 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.7 | 16.6 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.6 | 67.6 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.6 | 80.6 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.6 | 118.4 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.6 | 4.1 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.6 | 4.1 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.6 | 9.2 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.6 | 10.2 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.5 | 3.3 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.5 | 13.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.5 | 7.3 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.5 | 8.7 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.5 | 1.0 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.5 | 4.8 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.5 | 2.9 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.5 | 25.5 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.5 | 33.9 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.5 | 4.1 | REACTOME SIGNALING BY ERBB2 | Genes involved in Signaling by ERBB2 |
| 0.4 | 21.6 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.4 | 6.7 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.4 | 17.3 | REACTOME RNA POL I TRANSCRIPTION INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.4 | 8.3 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.4 | 3.0 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.4 | 2.5 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.4 | 18.6 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.4 | 4.4 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 0.4 | 3.6 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.4 | 2.8 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.4 | 9.8 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.4 | 10.3 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.4 | 8.3 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.4 | 5.2 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.4 | 5.8 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.3 | 10.7 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.3 | 12.5 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.3 | 14.0 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.3 | 6.4 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.3 | 6.1 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.3 | 1.5 | REACTOME GAP JUNCTION TRAFFICKING | Genes involved in Gap junction trafficking |
| 0.3 | 13.2 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.3 | 6.2 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.3 | 3.3 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 4.0 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.2 | 12.6 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.2 | 5.0 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.2 | 3.7 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 4.9 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.2 | 21.9 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.2 | 4.7 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.2 | 2.7 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.2 | 2.7 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 0.2 | 1.1 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.2 | 3.0 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 4.1 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 4.4 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 1.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 3.6 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 1.1 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 0.6 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.1 | 1.3 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 1.8 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 33.2 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 8.5 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 1.8 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.1 | 2.9 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.1 | 0.4 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.1 | 1.0 | REACTOME LIPOPROTEIN METABOLISM | Genes involved in Lipoprotein metabolism |
| 0.1 | 1.9 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 4.2 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.1 | 2.2 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 1.0 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 0.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 4.6 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 4.8 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 1.8 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.6 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 1.4 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.7 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.5 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.6 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.4 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |