Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for ZFX
Z-value: 8.13
Motif logo
Transcription factors associated with ZFX
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ZFX
|
ENSG00000005889.16 | ZFX |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZFX | hg38_v1_chrX_+_24149629_24149696 | -0.67 | 5.6e-30 | Click! |
Activity profile of ZFX motif
Sorted Z-values of ZFX motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ZFX
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 20.5 | 61.5 | GO:1901254 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 12.0 | 47.8 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 11.4 | 34.2 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 10.5 | 31.5 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 10.2 | 30.7 | GO:2000374 | regulation of oxygen metabolic process(GO:2000374) |
| 9.9 | 39.8 | GO:1903182 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 9.6 | 38.3 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 8.8 | 35.1 | GO:0043335 | protein unfolding(GO:0043335) |
| 8.6 | 25.7 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 8.2 | 33.0 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
| 7.9 | 23.6 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 7.7 | 100.0 | GO:0006265 | DNA topological change(GO:0006265) |
| 7.2 | 114.9 | GO:0045116 | protein neddylation(GO:0045116) |
| 6.8 | 20.5 | GO:0006864 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 6.7 | 26.8 | GO:0009838 | abscission(GO:0009838) |
| 6.7 | 20.1 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 6.6 | 19.9 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 6.2 | 24.8 | GO:1904116 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 6.1 | 24.6 | GO:1901535 | regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653) |
| 6.1 | 6.1 | GO:1903181 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) |
| 6.0 | 18.1 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 5.8 | 34.7 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
| 5.6 | 45.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 5.6 | 55.9 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 5.5 | 16.6 | GO:0006533 | fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) |
| 5.5 | 22.0 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 5.5 | 21.9 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 5.5 | 27.3 | GO:0002439 | chronic inflammatory response to antigenic stimulus(GO:0002439) |
| 5.4 | 38.0 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 5.1 | 20.6 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 5.0 | 15.0 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 5.0 | 19.9 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 4.7 | 23.7 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 4.7 | 42.2 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 4.6 | 13.9 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 4.6 | 36.6 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 4.6 | 18.2 | GO:0044571 | [2Fe-2S] cluster assembly(GO:0044571) |
| 4.5 | 36.3 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 4.5 | 4.5 | GO:0033386 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 4.4 | 22.2 | GO:0097240 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 4.3 | 39.1 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 4.3 | 47.3 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 4.3 | 29.9 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 4.2 | 33.8 | GO:0052405 | negative regulation by host of symbiont molecular function(GO:0052405) |
| 4.2 | 33.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 4.2 | 16.6 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 4.1 | 24.7 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
| 3.9 | 15.8 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 3.9 | 59.1 | GO:0070986 | left/right axis specification(GO:0070986) |
| 3.9 | 11.7 | GO:0071373 | cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 3.9 | 11.6 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 3.8 | 26.6 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 3.8 | 11.3 | GO:0061011 | hepatic duct development(GO:0061011) |
| 3.7 | 55.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 3.6 | 14.5 | GO:0036114 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 3.6 | 10.9 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 3.5 | 10.6 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 3.5 | 69.6 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 3.4 | 6.9 | GO:0034971 | histone H3-R17 methylation(GO:0034971) |
| 3.4 | 37.1 | GO:0035437 | maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 3.4 | 16.8 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 3.2 | 16.1 | GO:1900125 | regulation of hyaluronan biosynthetic process(GO:1900125) positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 3.2 | 9.7 | GO:1904688 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 3.2 | 25.3 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 3.1 | 9.4 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 3.1 | 46.9 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 3.1 | 9.2 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 3.1 | 9.2 | GO:0007174 | epidermal growth factor catabolic process(GO:0007174) |
| 3.0 | 18.3 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 3.0 | 8.9 | GO:0032079 | positive regulation of endodeoxyribonuclease activity(GO:0032079) regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) |
| 3.0 | 8.9 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 2.9 | 5.9 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 2.9 | 8.7 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 2.9 | 287.4 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 2.9 | 17.2 | GO:0042780 | tRNA 3'-end processing(GO:0042780) |
| 2.9 | 8.6 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
| 2.8 | 8.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 2.8 | 16.9 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 2.8 | 8.5 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
| 2.8 | 5.6 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 2.8 | 8.4 | GO:1902804 | negative regulation of synaptic vesicle transport(GO:1902804) |
| 2.8 | 27.7 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 2.8 | 35.9 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 2.7 | 10.9 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 2.7 | 5.4 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 2.7 | 8.0 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 2.6 | 15.8 | GO:0043103 | hypoxanthine salvage(GO:0043103) |
| 2.6 | 7.8 | GO:1903233 | regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) |
| 2.6 | 10.2 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 2.5 | 7.6 | GO:0051030 | snRNA transport(GO:0051030) |
| 2.5 | 12.7 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 2.5 | 7.6 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 2.5 | 10.1 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
| 2.5 | 7.4 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 2.4 | 21.9 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 2.4 | 26.8 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 2.4 | 14.3 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 2.3 | 7.0 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 2.3 | 34.7 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 2.3 | 20.8 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
| 2.3 | 15.9 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 2.3 | 43.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 2.3 | 6.8 | GO:0033122 | negative regulation of purine nucleotide catabolic process(GO:0033122) |
| 2.2 | 19.8 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 2.2 | 6.6 | GO:0019046 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
| 2.2 | 6.6 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) positive regulation of response to alcohol(GO:1901421) |
| 2.2 | 19.6 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 2.2 | 8.7 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 2.2 | 17.2 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 2.1 | 6.4 | GO:0097069 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 2.1 | 10.6 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 2.1 | 16.8 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 2.1 | 16.7 | GO:1990668 | vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668) |
| 2.1 | 2.1 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 2.1 | 51.6 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 2.1 | 6.2 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 2.1 | 6.2 | GO:1904732 | regulation of electron carrier activity(GO:1904732) |
| 2.0 | 14.3 | GO:0000212 | meiotic spindle organization(GO:0000212) |
| 2.0 | 6.1 | GO:0002572 | pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 2.0 | 26.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 2.0 | 28.1 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 2.0 | 81.7 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 2.0 | 13.8 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 1.9 | 19.4 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 1.9 | 27.1 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
| 1.9 | 11.6 | GO:0060356 | leucine import(GO:0060356) |
| 1.9 | 5.7 | GO:0032071 | regulation of endodeoxyribonuclease activity(GO:0032071) |
| 1.9 | 49.5 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 1.9 | 20.9 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 1.9 | 26.6 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) |
| 1.9 | 9.4 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 1.9 | 5.6 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 1.9 | 31.6 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 1.9 | 25.9 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 1.8 | 10.9 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 1.8 | 7.3 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 1.8 | 25.5 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 1.8 | 10.8 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 1.8 | 7.2 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 1.8 | 9.0 | GO:0034201 | response to oleic acid(GO:0034201) |
| 1.8 | 7.2 | GO:0034351 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 1.8 | 19.7 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 1.8 | 7.1 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 1.8 | 8.9 | GO:0030242 | pexophagy(GO:0030242) |
| 1.8 | 7.0 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 1.8 | 38.5 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 1.7 | 7.0 | GO:0043366 | beta selection(GO:0043366) |
| 1.7 | 5.1 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 1.7 | 15.1 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 1.7 | 3.3 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 1.7 | 8.3 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 1.7 | 16.5 | GO:0097033 | mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 1.6 | 1.6 | GO:0090169 | regulation of spindle assembly(GO:0090169) |
| 1.6 | 35.7 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 1.6 | 6.4 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 1.6 | 11.2 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 1.6 | 12.8 | GO:0030091 | protein repair(GO:0030091) |
| 1.6 | 9.6 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255) |
| 1.6 | 11.2 | GO:0032218 | riboflavin transport(GO:0032218) |
| 1.6 | 9.5 | GO:0043248 | proteasome assembly(GO:0043248) |
| 1.6 | 26.8 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 1.6 | 6.2 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 1.5 | 4.6 | GO:0000967 | endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471) |
| 1.5 | 7.7 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 1.5 | 23.1 | GO:0000338 | protein deneddylation(GO:0000338) |
| 1.5 | 12.3 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 1.5 | 16.8 | GO:0007144 | female meiosis I(GO:0007144) |
| 1.5 | 13.7 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 1.5 | 5.9 | GO:0003285 | septum secundum development(GO:0003285) atrial septum secundum morphogenesis(GO:0003290) |
| 1.5 | 14.5 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 1.5 | 20.3 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 1.4 | 13.0 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 1.4 | 4.3 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 1.4 | 59.8 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 1.4 | 9.9 | GO:0097680 | cellular hyperosmotic salinity response(GO:0071475) double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 1.4 | 9.9 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 1.4 | 5.6 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 1.4 | 16.7 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 1.4 | 16.4 | GO:0007379 | segment specification(GO:0007379) |
| 1.4 | 2.7 | GO:1900110 | negative regulation of histone H3-K9 dimethylation(GO:1900110) |
| 1.3 | 2.7 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
| 1.3 | 6.7 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 1.3 | 5.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 1.3 | 12.0 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 1.3 | 4.0 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 1.3 | 18.5 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 1.3 | 4.0 | GO:0018406 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 1.3 | 9.2 | GO:0010710 | regulation of collagen catabolic process(GO:0010710) |
| 1.3 | 5.2 | GO:0050689 | negative regulation of defense response to virus by host(GO:0050689) |
| 1.3 | 5.2 | GO:0009137 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 1.2 | 20.0 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 1.2 | 6.1 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 1.2 | 29.3 | GO:0006465 | signal peptide processing(GO:0006465) |
| 1.2 | 40.3 | GO:0097421 | liver regeneration(GO:0097421) |
| 1.2 | 14.6 | GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) |
| 1.2 | 35.2 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 1.2 | 6.0 | GO:0006788 | heme oxidation(GO:0006788) |
| 1.2 | 6.0 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 1.2 | 7.2 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 1.2 | 4.8 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 1.2 | 23.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 1.2 | 8.3 | GO:0072718 | response to cisplatin(GO:0072718) |
| 1.2 | 3.5 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 1.2 | 5.9 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 1.2 | 8.2 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 1.1 | 15.9 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 1.1 | 9.0 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 1.1 | 6.7 | GO:0097338 | response to clozapine(GO:0097338) |
| 1.1 | 3.3 | GO:2000767 | positive regulation of cytoplasmic translation(GO:2000767) |
| 1.1 | 5.6 | GO:0046070 | dGTP metabolic process(GO:0046070) |
| 1.1 | 12.2 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 1.1 | 14.3 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 1.1 | 8.8 | GO:0045176 | apical protein localization(GO:0045176) |
| 1.1 | 11.0 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 1.1 | 5.5 | GO:1904501 | glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of centromeric sister chromatid cohesion(GO:0070602) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) |
| 1.1 | 66.4 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 1.1 | 21.6 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 1.1 | 6.5 | GO:0075509 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 1.1 | 15.1 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
| 1.1 | 33.2 | GO:0090383 | phagosome acidification(GO:0090383) |
| 1.1 | 25.7 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 1.1 | 7.5 | GO:0010985 | regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) negative regulation of lipoprotein particle clearance(GO:0010985) |
| 1.1 | 4.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 1.1 | 11.6 | GO:0042262 | DNA protection(GO:0042262) |
| 1.0 | 7.3 | GO:0010626 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) |
| 1.0 | 3.1 | GO:1903006 | flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006) |
| 1.0 | 3.1 | GO:0006524 | alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) |
| 1.0 | 5.2 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 1.0 | 3.1 | GO:1902960 | protein retention in Golgi apparatus(GO:0045053) regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 1.0 | 14.3 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 1.0 | 22.2 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 1.0 | 11.0 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 1.0 | 3.9 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.9 | 3.8 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.9 | 7.6 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.9 | 16.8 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.9 | 1.8 | GO:0031125 | rRNA 3'-end processing(GO:0031125) |
| 0.9 | 13.5 | GO:0000022 | mitotic spindle elongation(GO:0000022) |
| 0.9 | 59.5 | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) |
| 0.9 | 7.2 | GO:0002176 | male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093) |
| 0.9 | 14.3 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.9 | 7.9 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.9 | 6.1 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.9 | 4.3 | GO:0061734 | parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) |
| 0.9 | 4.3 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.9 | 6.0 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.9 | 58.3 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.9 | 18.0 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.9 | 7.7 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 0.8 | 6.7 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.8 | 16.7 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.8 | 2.5 | GO:0036233 | glycine import(GO:0036233) |
| 0.8 | 4.2 | GO:0061087 | regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.8 | 2.5 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) |
| 0.8 | 1.6 | GO:1903525 | regulation of membrane tubulation(GO:1903525) |
| 0.8 | 6.5 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.8 | 2.4 | GO:0036363 | transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 0.8 | 2.4 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.8 | 3.2 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.8 | 5.6 | GO:0032075 | positive regulation of nuclease activity(GO:0032075) |
| 0.8 | 4.0 | GO:1902659 | regulation of glucose mediated signaling pathway(GO:1902659) |
| 0.8 | 18.3 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.8 | 14.3 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.8 | 7.1 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 0.8 | 18.9 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 0.8 | 18.1 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.8 | 4.7 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.8 | 4.7 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.8 | 6.9 | GO:2000582 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.8 | 23.7 | GO:0006283 | transcription-coupled nucleotide-excision repair(GO:0006283) |
| 0.8 | 5.3 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.8 | 3.8 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.8 | 12.9 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.8 | 3.0 | GO:0009648 | photoperiodism(GO:0009648) |
| 0.8 | 4.5 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.8 | 17.3 | GO:0043489 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
| 0.8 | 1.5 | GO:0002442 | serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554) |
| 0.7 | 5.2 | GO:1902730 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.7 | 16.9 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.7 | 3.6 | GO:0090034 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
| 0.7 | 7.2 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.7 | 3.6 | GO:0031585 | regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) |
| 0.7 | 5.0 | GO:0098877 | neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540) |
| 0.7 | 5.7 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.7 | 8.6 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.7 | 2.9 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 0.7 | 1.4 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 0.7 | 18.6 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.7 | 7.5 | GO:0006538 | glutamate catabolic process(GO:0006538) |
| 0.7 | 8.1 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.7 | 2.0 | GO:0048382 | mesendoderm development(GO:0048382) |
| 0.7 | 14.0 | GO:0030262 | apoptotic nuclear changes(GO:0030262) |
| 0.7 | 5.3 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.7 | 5.3 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.7 | 10.6 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.7 | 21.8 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.7 | 7.9 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.6 | 46.1 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.6 | 5.8 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.6 | 1.9 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 0.6 | 4.9 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.6 | 49.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.6 | 22.0 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.6 | 13.5 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.6 | 4.3 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.6 | 6.1 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.6 | 1.8 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.6 | 21.9 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.6 | 7.9 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.6 | 7.8 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.6 | 6.0 | GO:0030638 | polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
| 0.6 | 12.5 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
| 0.6 | 20.8 | GO:0043928 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.6 | 4.1 | GO:0030656 | regulation of vitamin metabolic process(GO:0030656) |
| 0.6 | 5.3 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.6 | 1.2 | GO:0007506 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) gonadal mesoderm development(GO:0007506) |
| 0.6 | 4.1 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.6 | 27.9 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.6 | 5.8 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.6 | 11.3 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.6 | 24.3 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.6 | 8.4 | GO:2000188 | regulation of cholesterol homeostasis(GO:2000188) |
| 0.6 | 3.9 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.5 | 6.5 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.5 | 1.1 | GO:0000189 | MAPK import into nucleus(GO:0000189) |
| 0.5 | 1.6 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.5 | 39.4 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.5 | 2.1 | GO:0065001 | negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572) specification of axis polarity(GO:0065001) |
| 0.5 | 3.7 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.5 | 18.5 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.5 | 15.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.5 | 14.5 | GO:0043631 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 0.5 | 4.0 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.5 | 8.0 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.5 | 17.9 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.5 | 19.3 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.5 | 5.9 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.5 | 10.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.5 | 14.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.5 | 3.9 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.5 | 7.1 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 0.5 | 16.8 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.5 | 24.0 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.5 | 1.4 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.5 | 15.5 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.5 | 2.7 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.5 | 11.0 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
| 0.5 | 25.1 | GO:0032392 | DNA geometric change(GO:0032392) |
| 0.5 | 5.0 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
| 0.4 | 4.0 | GO:0043382 | regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) |
| 0.4 | 6.2 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.4 | 3.1 | GO:1901985 | positive regulation of protein acetylation(GO:1901985) |
| 0.4 | 20.8 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.4 | 4.4 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.4 | 1.3 | GO:0007549 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.4 | 3.9 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.4 | 1.3 | GO:0072396 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 0.4 | 7.2 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.4 | 1.7 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.4 | 6.3 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.4 | 6.6 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.4 | 2.9 | GO:0070236 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.4 | 1.6 | GO:1903659 | regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.4 | 11.0 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.4 | 3.2 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.4 | 1.2 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.4 | 1.6 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.4 | 2.7 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.4 | 3.4 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.4 | 3.0 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.4 | 0.8 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.4 | 6.3 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.4 | 7.6 | GO:0051452 | intracellular pH reduction(GO:0051452) |
| 0.4 | 5.0 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.4 | 2.1 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.4 | 3.5 | GO:0014894 | response to stimulus involved in regulation of muscle adaptation(GO:0014874) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.3 | 54.6 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.3 | 2.4 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
| 0.3 | 1.7 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.3 | 3.9 | GO:0017004 | cytochrome complex assembly(GO:0017004) |
| 0.3 | 1.3 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.3 | 4.1 | GO:0090205 | positive regulation of cholesterol metabolic process(GO:0090205) |
| 0.3 | 1.5 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 0.3 | 2.1 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.3 | 10.1 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.3 | 1.5 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.3 | 1.5 | GO:0097021 | Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021) |
| 0.3 | 10.8 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
| 0.3 | 13.9 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 0.3 | 1.4 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.3 | 1.4 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.3 | 3.6 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.3 | 1.1 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 0.3 | 43.0 | GO:0006413 | translational initiation(GO:0006413) |
| 0.3 | 1.6 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.3 | 1.8 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.3 | 7.3 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.3 | 20.3 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.2 | 6.9 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.2 | 4.2 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.2 | 1.9 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
| 0.2 | 0.7 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
| 0.2 | 0.2 | GO:0010040 | response to iron(II) ion(GO:0010040) |
| 0.2 | 3.7 | GO:1901070 | GTP biosynthetic process(GO:0006183) guanosine-containing compound biosynthetic process(GO:1901070) |
| 0.2 | 3.7 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.2 | 2.5 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.2 | 116.1 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.2 | 2.9 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.2 | 0.2 | GO:0031498 | chromatin disassembly(GO:0031498) |
| 0.2 | 24.4 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.2 | 4.2 | GO:0046337 | phosphatidylethanolamine metabolic process(GO:0046337) |
| 0.2 | 3.1 | GO:0042921 | corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921) |
| 0.2 | 4.5 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.2 | 0.4 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.2 | 2.0 | GO:0032495 | response to muramyl dipeptide(GO:0032495) |
| 0.2 | 9.5 | GO:0090307 | mitotic spindle assembly(GO:0090307) |
| 0.2 | 1.3 | GO:1904754 | positive regulation of vascular associated smooth muscle cell migration(GO:1904754) |
| 0.2 | 2.4 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.2 | 6.6 | GO:0071391 | cellular response to estrogen stimulus(GO:0071391) |
| 0.2 | 12.7 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.2 | 0.3 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 0.2 | 0.2 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.2 | 1.7 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
| 0.2 | 0.2 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.2 | 1.3 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.2 | 6.2 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.2 | 2.9 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 2.4 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.1 | 6.2 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.1 | 2.0 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.1 | 1.0 | GO:0008215 | spermine metabolic process(GO:0008215) |
| 0.1 | 0.3 | GO:0003064 | regulation of heart rate by hormone(GO:0003064) |
| 0.1 | 0.6 | GO:0036109 | alpha-linolenic acid metabolic process(GO:0036109) |
| 0.1 | 7.0 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.1 | 4.0 | GO:0046949 | fatty-acyl-CoA biosynthetic process(GO:0046949) |
| 0.1 | 6.6 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) |
| 0.1 | 2.0 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.1 | 4.5 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.1 | 1.8 | GO:0044803 | multi-organism membrane organization(GO:0044803) |
| 0.1 | 2.6 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.1 | 0.5 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
| 0.1 | 1.2 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.1 | 3.3 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) |
| 0.1 | 6.3 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.1 | 2.6 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.1 | 0.9 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.1 | 0.5 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.1 | 0.2 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) |
| 0.1 | 6.3 | GO:0090114 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114) |
| 0.1 | 3.2 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 1.3 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 1.0 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.1 | 1.0 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.1 | 0.8 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 8.5 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
| 0.1 | 4.9 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 1.8 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.1 | 1.0 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.1 | 0.4 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.1 | 1.1 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.1 | 2.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 1.5 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.1 | 0.1 | GO:0061643 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 0.1 | 1.0 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.1 | 0.6 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
| 0.1 | 1.8 | GO:0032755 | positive regulation of interleukin-6 production(GO:0032755) |
| 0.1 | 1.7 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 1.4 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.1 | 1.0 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.1 | 1.5 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.1 | 5.0 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.1 | 4.1 | GO:0097202 | activation of cysteine-type endopeptidase activity(GO:0097202) |
| 0.1 | 1.3 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.1 | 0.1 | GO:0061010 | gall bladder development(GO:0061010) |
| 0.1 | 0.3 | GO:0060710 | chorio-allantoic fusion(GO:0060710) |
| 0.1 | 1.3 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.1 | 1.4 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 0.8 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.3 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.0 | 0.5 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
| 0.0 | 0.3 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.0 | 0.5 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.0 | 2.0 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.0 | 0.0 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.0 | 0.7 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.0 | 0.1 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.0 | 0.2 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.0 | 0.4 | GO:1902041 | regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) |
| 0.0 | 0.5 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.2 | GO:0003209 | cardiac atrium morphogenesis(GO:0003209) |
| 0.0 | 0.4 | GO:0035722 | interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 20.5 | 61.5 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 17.3 | 51.9 | GO:0036284 | tubulobulbar complex(GO:0036284) |
| 9.9 | 39.8 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 9.0 | 107.9 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 8.3 | 24.8 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 6.6 | 59.1 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 6.5 | 19.4 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 6.4 | 63.7 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 6.1 | 18.4 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 5.7 | 28.5 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 4.7 | 32.7 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 4.5 | 13.4 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 4.4 | 26.5 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 4.2 | 16.8 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 4.2 | 16.8 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 4.1 | 12.2 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 4.0 | 28.1 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 4.0 | 36.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 4.0 | 19.8 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 4.0 | 15.9 | GO:0044307 | dendritic branch(GO:0044307) |
| 3.6 | 32.3 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 3.5 | 38.0 | GO:0042587 | glycogen granule(GO:0042587) |
| 3.4 | 24.0 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 3.3 | 16.7 | GO:0042825 | TAP complex(GO:0042825) |
| 3.2 | 45.0 | GO:0090543 | Flemming body(GO:0090543) |
| 3.2 | 12.8 | GO:0005683 | U7 snRNP(GO:0005683) |
| 3.2 | 15.8 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 3.1 | 9.2 | GO:0032419 | extrinsic component of lysosome membrane(GO:0032419) |
| 3.1 | 9.2 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
| 3.0 | 8.9 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 2.9 | 29.4 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 2.9 | 29.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 2.9 | 11.5 | GO:0071942 | XPC complex(GO:0071942) |
| 2.8 | 42.4 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 2.8 | 38.8 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 2.8 | 8.3 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 2.8 | 30.3 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 2.6 | 10.6 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 2.6 | 18.2 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 2.6 | 72.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 2.5 | 58.4 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 2.5 | 7.5 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 2.5 | 17.3 | GO:0016589 | NURF complex(GO:0016589) |
| 2.4 | 12.2 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 2.4 | 12.1 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 2.4 | 36.2 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 2.4 | 16.9 | GO:0016272 | prefoldin complex(GO:0016272) |
| 2.4 | 14.3 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 2.3 | 25.6 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 2.2 | 15.3 | GO:0031415 | NatA complex(GO:0031415) |
| 2.2 | 17.4 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 2.2 | 34.7 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 2.1 | 8.6 | GO:0071920 | cleavage body(GO:0071920) |
| 2.1 | 15.0 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 2.1 | 8.6 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 2.1 | 6.4 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 2.1 | 4.2 | GO:0035061 | interchromatin granule(GO:0035061) |
| 2.1 | 8.2 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 2.0 | 10.2 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 2.0 | 14.1 | GO:0032021 | NELF complex(GO:0032021) |
| 2.0 | 2.0 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 2.0 | 9.9 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 2.0 | 17.9 | GO:0042382 | paraspeckles(GO:0042382) |
| 2.0 | 7.9 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
| 1.9 | 42.8 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 1.9 | 11.6 | GO:0001940 | male pronucleus(GO:0001940) |
| 1.9 | 3.8 | GO:0031332 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 1.9 | 5.6 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 1.9 | 13.0 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 1.8 | 1.8 | GO:0019034 | viral replication complex(GO:0019034) |
| 1.8 | 7.2 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 1.8 | 9.0 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 1.8 | 31.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 1.8 | 112.5 | GO:0000502 | proteasome complex(GO:0000502) |
| 1.7 | 8.6 | GO:0032449 | CBM complex(GO:0032449) |
| 1.7 | 5.1 | GO:0030689 | Noc complex(GO:0030689) |
| 1.7 | 77.8 | GO:0090544 | BAF-type complex(GO:0090544) |
| 1.7 | 10.1 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 1.6 | 13.0 | GO:0005827 | polar microtubule(GO:0005827) |
| 1.6 | 17.9 | GO:0070449 | elongin complex(GO:0070449) |
| 1.6 | 16.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 1.6 | 28.8 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 1.6 | 20.4 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 1.6 | 10.9 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 1.5 | 13.7 | GO:0044754 | autolysosome(GO:0044754) |
| 1.5 | 25.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 1.5 | 11.9 | GO:0034518 | RNA cap binding complex(GO:0034518) |
| 1.5 | 11.8 | GO:0070187 | telosome(GO:0070187) |
| 1.5 | 7.4 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 1.4 | 20.2 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 1.4 | 8.5 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 1.4 | 19.7 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 1.4 | 8.4 | GO:0034709 | methylosome(GO:0034709) |
| 1.4 | 22.4 | GO:0097470 | ribbon synapse(GO:0097470) |
| 1.4 | 20.8 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 1.4 | 4.2 | GO:0005745 | m-AAA complex(GO:0005745) |
| 1.3 | 9.4 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 1.3 | 224.4 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 1.3 | 6.6 | GO:0031523 | Myb complex(GO:0031523) |
| 1.3 | 43.1 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 1.2 | 7.5 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 1.2 | 24.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 1.1 | 3.4 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 1.1 | 14.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 1.1 | 36.9 | GO:0005844 | polysome(GO:0005844) |
| 1.1 | 27.9 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 1.1 | 17.1 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 1.1 | 4.2 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 1.1 | 11.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 1.0 | 6.2 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 1.0 | 9.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 1.0 | 8.2 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 1.0 | 4.0 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 1.0 | 67.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 1.0 | 6.7 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 1.0 | 5.7 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.9 | 8.4 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.9 | 21.0 | GO:0046930 | pore complex(GO:0046930) |
| 0.9 | 7.3 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.9 | 9.8 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.9 | 10.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.9 | 12.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.9 | 11.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.8 | 11.9 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.8 | 83.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.8 | 12.6 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
| 0.8 | 13.3 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.8 | 47.3 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.8 | 12.9 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.8 | 8.0 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.8 | 94.6 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.8 | 13.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.8 | 10.2 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.8 | 74.1 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.8 | 4.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.8 | 9.8 | GO:0010369 | chromocenter(GO:0010369) |
| 0.7 | 5.2 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.7 | 9.7 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.7 | 5.9 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.7 | 6.7 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.7 | 7.4 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.7 | 5.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.7 | 1.4 | GO:1903349 | omegasome membrane(GO:1903349) |
| 0.7 | 6.9 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.7 | 1.4 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.7 | 6.2 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.7 | 17.1 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.7 | 4.8 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.7 | 2.7 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.7 | 62.9 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.7 | 57.3 | GO:0005811 | lipid particle(GO:0005811) |
| 0.7 | 6.7 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.7 | 18.5 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.7 | 28.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.7 | 3.3 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.7 | 5.9 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.6 | 3.9 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 0.6 | 5.7 | GO:0070938 | contractile ring(GO:0070938) |
| 0.6 | 5.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.6 | 3.1 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.6 | 3.0 | GO:0032044 | DSIF complex(GO:0032044) |
| 0.6 | 15.6 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.6 | 15.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.6 | 22.8 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.6 | 3.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.6 | 4.4 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.6 | 30.4 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.5 | 7.0 | GO:0030677 | ribonuclease P complex(GO:0030677) |
| 0.5 | 8.6 | GO:0031932 | TORC2 complex(GO:0031932) TOR complex(GO:0038201) |
| 0.5 | 22.8 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.5 | 2.0 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
| 0.5 | 2.5 | GO:0030891 | VCB complex(GO:0030891) |
| 0.5 | 7.5 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.5 | 1.5 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.5 | 3.6 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.4 | 14.7 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.4 | 19.5 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.4 | 4.4 | GO:0098574 | cytoplasmic side of lysosomal membrane(GO:0098574) |
| 0.4 | 1.3 | GO:0000805 | X chromosome(GO:0000805) |
| 0.4 | 6.9 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.4 | 1.7 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.4 | 5.3 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.4 | 41.0 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.4 | 35.4 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.4 | 16.5 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.4 | 9.0 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.4 | 6.5 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.4 | 4.1 | GO:0005638 | lamin filament(GO:0005638) |
| 0.4 | 0.7 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.4 | 10.3 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.4 | 15.9 | GO:0015030 | Cajal body(GO:0015030) |
| 0.4 | 8.3 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.4 | 3.6 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.4 | 1.1 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.4 | 15.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.3 | 2.1 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.3 | 18.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.3 | 17.5 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.3 | 7.3 | GO:0016592 | mediator complex(GO:0016592) |
| 0.3 | 25.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.3 | 11.5 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.3 | 13.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.3 | 6.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.3 | 5.3 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.3 | 35.6 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.2 | 0.7 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.2 | 70.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.2 | 45.9 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.2 | 13.6 | GO:0019866 | organelle inner membrane(GO:0019866) |
| 0.2 | 2.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.2 | 22.4 | GO:0016605 | PML body(GO:0016605) |
| 0.2 | 75.2 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.2 | 0.8 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.2 | 3.1 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 3.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.2 | 0.7 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.2 | 10.7 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.2 | 1.4 | GO:0072487 | MSL complex(GO:0072487) |
| 0.2 | 4.7 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.2 | 2.0 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 5.9 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 9.0 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 3.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 2.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 19.9 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 0.3 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.1 | 53.0 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 3.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 2.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 1.8 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.1 | 0.9 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.1 | 0.9 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 26.5 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.1 | 0.3 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
| 0.1 | 1.2 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 4.0 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.7 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.6 | GO:0070820 | tertiary granule(GO:0070820) |
| 0.0 | 0.7 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 3.8 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 1.0 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.5 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 14.8 | 59.3 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 12.4 | 37.1 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 12.0 | 47.8 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 11.6 | 34.7 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 10.7 | 74.7 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 10.5 | 31.5 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 10.2 | 61.5 | GO:0034046 | poly(G) binding(GO:0034046) |
| 9.9 | 39.8 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 8.6 | 25.8 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 7.4 | 37.0 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 6.9 | 27.7 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 6.8 | 20.5 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 6.8 | 6.8 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 6.7 | 33.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 6.5 | 45.7 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 6.3 | 38.0 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 6.3 | 18.9 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 6.2 | 31.2 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 6.1 | 54.6 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 5.6 | 16.7 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 5.5 | 16.6 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 5.5 | 16.6 | GO:0080130 | L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 5.4 | 32.3 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 5.1 | 15.4 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 5.0 | 19.9 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 4.9 | 14.8 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 4.8 | 14.3 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 4.5 | 125.1 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 4.4 | 13.1 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 4.0 | 19.8 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 3.6 | 18.1 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 3.6 | 14.3 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 3.5 | 14.2 | GO:0046573 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 3.5 | 24.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 3.3 | 29.4 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 3.2 | 38.8 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 3.2 | 25.3 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 3.1 | 15.5 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 3.1 | 9.3 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 3.1 | 9.3 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) |
| 3.1 | 12.3 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 3.0 | 9.0 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 2.9 | 35.1 | GO:0030911 | TPR domain binding(GO:0030911) |
| 2.9 | 133.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 2.9 | 20.1 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 2.9 | 28.7 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 2.9 | 2.9 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 2.8 | 8.4 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 2.8 | 14.0 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 2.8 | 113.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 2.8 | 22.2 | GO:0015288 | porin activity(GO:0015288) |
| 2.7 | 24.7 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 2.7 | 19.2 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 2.7 | 13.6 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 2.7 | 13.4 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 2.7 | 16.0 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 2.6 | 21.2 | GO:0050733 | RS domain binding(GO:0050733) |
| 2.6 | 10.6 | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 2.6 | 78.9 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 2.6 | 44.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 2.6 | 10.4 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 2.6 | 51.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 2.6 | 10.2 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 2.5 | 25.5 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 2.5 | 12.6 | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 2.4 | 14.6 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 2.4 | 7.2 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 2.4 | 9.6 | GO:0051748 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 2.4 | 7.1 | GO:0034512 | box C/D snoRNA binding(GO:0034512) |
| 2.3 | 29.9 | GO:0008494 | translation activator activity(GO:0008494) |
| 2.2 | 30.7 | GO:0046790 | virion binding(GO:0046790) |
| 2.2 | 6.5 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 2.2 | 8.6 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 2.1 | 8.6 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 2.1 | 6.4 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 2.1 | 6.4 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 2.1 | 12.5 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 2.0 | 6.1 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 2.0 | 4.0 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 1.9 | 44.8 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 1.9 | 11.6 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 1.9 | 7.7 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 1.9 | 7.5 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 1.9 | 9.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 1.8 | 70.0 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 1.7 | 8.5 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 1.7 | 5.1 | GO:0004315 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 1.7 | 15.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 1.7 | 11.6 | GO:0030613 | oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) |
| 1.6 | 14.5 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 1.6 | 19.3 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 1.6 | 6.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 1.6 | 20.8 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 1.6 | 11.2 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 1.6 | 11.2 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 1.6 | 4.8 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 1.6 | 4.7 | GO:0047012 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012) |
| 1.6 | 14.0 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 1.5 | 4.6 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 1.5 | 59.4 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 1.5 | 35.0 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 1.5 | 15.0 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 1.5 | 6.0 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 1.5 | 10.4 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 1.5 | 10.4 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 1.4 | 14.4 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 1.4 | 2.9 | GO:0031762 | alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) |
| 1.4 | 35.5 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 1.4 | 17.0 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 1.4 | 9.9 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 1.4 | 60.8 | GO:0061650 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 1.4 | 25.0 | GO:0000339 | RNA cap binding(GO:0000339) |
| 1.4 | 78.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 1.4 | 8.2 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 1.4 | 4.1 | GO:0050146 | nucleoside phosphotransferase activity(GO:0050146) |
| 1.3 | 9.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 1.3 | 4.0 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 1.3 | 11.9 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 1.3 | 3.9 | GO:0098518 | polynucleotide phosphatase activity(GO:0098518) |
| 1.3 | 18.0 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 1.3 | 3.8 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 1.3 | 32.9 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 1.3 | 12.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 1.3 | 7.5 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 1.2 | 30.9 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 1.2 | 45.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 1.2 | 101.5 | GO:0019003 | GDP binding(GO:0019003) |
| 1.2 | 23.2 | GO:0043495 | protein anchor(GO:0043495) |
| 1.2 | 6.0 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 1.2 | 6.0 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 1.2 | 9.4 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 1.1 | 9.2 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 1.1 | 8.0 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 1.1 | 12.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 1.1 | 4.4 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 1.1 | 6.7 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 1.1 | 59.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 1.1 | 9.9 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 1.1 | 23.9 | GO:0044769 | hydrogen-exporting ATPase activity(GO:0036442) ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 1.1 | 11.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 1.1 | 4.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 1.1 | 9.6 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 1.1 | 4.2 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 1.1 | 30.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 1.1 | 24.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 1.1 | 21.0 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 1.0 | 18.7 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 1.0 | 11.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 1.0 | 14.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 1.0 | 28.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 1.0 | 8.8 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 1.0 | 6.7 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 1.0 | 7.7 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 1.0 | 6.7 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 1.0 | 3.8 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.9 | 5.6 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.9 | 8.4 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.9 | 9.0 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.9 | 4.5 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.9 | 16.0 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.9 | 9.7 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.9 | 14.9 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.9 | 15.6 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.9 | 8.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.8 | 23.8 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.8 | 2.5 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.8 | 3.3 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.8 | 35.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.8 | 4.9 | GO:0008381 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.8 | 3.2 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 0.8 | 27.1 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.8 | 14.3 | GO:1901611 | phosphatidylglycerol binding(GO:1901611) |
| 0.8 | 7.9 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.8 | 7.1 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.8 | 19.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.7 | 6.6 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.7 | 2.2 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.7 | 5.7 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.7 | 2.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.7 | 1.4 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.7 | 13.4 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.7 | 13.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.7 | 6.9 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.7 | 6.2 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.7 | 8.8 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.7 | 4.0 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064) |
| 0.7 | 11.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.7 | 11.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.7 | 5.9 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.6 | 5.2 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.6 | 2.6 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.6 | 3.2 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.6 | 1.9 | GO:0070363 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial light strand promoter sense binding(GO:0070363) mitochondrial heavy strand promoter sense binding(GO:0070364) |
| 0.6 | 14.4 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.6 | 17.4 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.6 | 3.1 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.6 | 5.6 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.6 | 1.8 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.6 | 1.8 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 0.6 | 1.8 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.6 | 3.0 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.6 | 7.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.6 | 50.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.6 | 8.3 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.6 | 1.8 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.6 | 5.2 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.6 | 5.7 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.6 | 5.1 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.6 | 27.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.6 | 12.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.6 | 5.1 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.6 | 9.5 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.5 | 3.3 | GO:0022884 | macromolecule transmembrane transporter activity(GO:0022884) nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.5 | 2.7 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 0.5 | 3.1 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.5 | 4.7 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.5 | 6.7 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.5 | 4.1 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.5 | 4.1 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.5 | 2.5 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.5 | 3.9 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.5 | 10.7 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.5 | 9.6 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.5 | 46.7 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.5 | 10.7 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.5 | 12.1 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.5 | 38.1 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.5 | 44.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.4 | 4.9 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.4 | 6.7 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.4 | 53.6 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.4 | 4.0 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.4 | 27.0 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.4 | 1.3 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.4 | 5.4 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.4 | 3.3 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.4 | 5.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.4 | 3.2 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.4 | 0.8 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.4 | 6.3 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.4 | 21.1 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.4 | 11.9 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.4 | 72.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.4 | 3.8 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.4 | 3.4 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.4 | 1.5 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.4 | 2.6 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.4 | 6.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.4 | 2.9 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.4 | 7.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.4 | 2.1 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.3 | 5.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.3 | 5.9 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.3 | 11.1 | GO:0043531 | ADP binding(GO:0043531) |
| 0.3 | 5.2 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.3 | 3.1 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.3 | 63.8 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.3 | 53.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.3 | 4.1 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.3 | 2.8 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.3 | 1.9 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.3 | 14.2 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.3 | 1.5 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.3 | 2.7 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.3 | 0.9 | GO:0000285 | 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 0.3 | 113.5 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.3 | 99.8 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.3 | 0.9 | GO:0052726 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol pentakisphosphate phosphatase activity(GO:0052827) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 0.3 | 6.7 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.3 | 4.4 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.3 | 35.9 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.3 | 9.9 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.3 | 3.7 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.3 | 12.2 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.3 | 4.0 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.3 | 1.1 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.3 | 15.2 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.3 | 0.8 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.3 | 5.1 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.3 | 2.0 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.2 | 1.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.2 | 1.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.2 | 16.2 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.2 | 4.6 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.2 | 0.7 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.2 | 6.4 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
| 0.2 | 10.0 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.2 | 25.6 | GO:0004386 | helicase activity(GO:0004386) |
| 0.2 | 12.6 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 0.2 | 0.8 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.2 | 7.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.2 | 3.1 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.2 | 0.6 | GO:0070704 | C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704) |
| 0.2 | 8.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 1.2 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.2 | 0.5 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.2 | 2.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 2.0 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.2 | 1.5 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.2 | 162.8 | GO:0003723 | RNA binding(GO:0003723) |
| 0.2 | 1.7 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 7.8 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.1 | 2.7 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.1 | 0.5 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.1 | 1.0 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.1 | 9.2 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.1 | 1.0 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.1 | 1.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 2.4 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 0.8 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.1 | 0.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 2.6 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 1.5 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.1 | 0.7 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.1 | 2.6 | GO:0042165 | neurotransmitter binding(GO:0042165) |
| 0.1 | 1.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 1.7 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.5 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.1 | 1.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 2.1 | GO:0004950 | G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) |
| 0.0 | 0.4 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.0 | 0.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673) |
| 0.0 | 0.2 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.0 | 1.3 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.1 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.0 | 0.5 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.2 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.0 | 0.2 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 106.5 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 3.2 | 129.1 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 2.3 | 62.7 | PID ARF 3PATHWAY | Arf1 pathway |
| 2.1 | 106.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 1.8 | 19.6 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 1.7 | 151.6 | PID P53 REGULATION PATHWAY | p53 pathway |
| 1.7 | 37.7 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 1.7 | 64.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 1.7 | 71.1 | PID ALK1 PATHWAY | ALK1 signaling events |
| 1.7 | 28.7 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 1.6 | 20.7 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 1.0 | 118.1 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.9 | 57.9 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.8 | 66.2 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.8 | 52.9 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.8 | 24.0 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.7 | 9.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.6 | 14.5 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.6 | 34.4 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.6 | 14.3 | PID ATM PATHWAY | ATM pathway |
| 0.6 | 42.6 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.6 | 2.3 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.6 | 46.1 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.6 | 22.0 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.6 | 24.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.6 | 22.1 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.5 | 23.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.5 | 7.8 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.4 | 9.9 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.4 | 12.4 | PID FOXO PATHWAY | FoxO family signaling |
| 0.4 | 2.6 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.4 | 6.5 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.4 | 2.9 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.4 | 9.2 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.3 | 6.2 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.3 | 27.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.3 | 6.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.3 | 31.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.3 | 14.7 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.3 | 10.4 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.3 | 5.8 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.3 | 17.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.3 | 6.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.3 | 8.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.3 | 12.3 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.3 | 15.5 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.2 | 2.8 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.2 | 3.9 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.2 | 2.9 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.2 | 6.2 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.2 | 12.6 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.2 | 8.8 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.2 | 4.4 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.2 | 5.7 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.2 | 10.0 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.2 | 5.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.2 | 9.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.2 | 9.9 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 5.8 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 2.0 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 1.8 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 4.6 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 2.0 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 1.3 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 1.9 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 2.6 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.1 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 62.2 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 4.0 | 312.9 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
| 3.1 | 124.3 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 3.1 | 65.1 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 2.8 | 13.8 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 2.2 | 22.3 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 2.2 | 30.7 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 2.0 | 28.6 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 2.0 | 45.0 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 1.9 | 40.3 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 1.9 | 39.1 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 1.8 | 27.4 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 1.8 | 36.0 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 1.8 | 41.1 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 1.8 | 31.8 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 1.7 | 12.2 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 1.7 | 50.5 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 1.7 | 13.4 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 1.7 | 60.1 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 1.7 | 21.7 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 1.7 | 49.7 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 1.7 | 1.7 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 1.6 | 8.2 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 1.6 | 34.0 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 1.6 | 46.8 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 1.6 | 29.6 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 1.5 | 63.6 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 1.5 | 11.8 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 1.4 | 105.5 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 1.4 | 15.0 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 1.4 | 71.9 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 1.4 | 82.7 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 1.3 | 116.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 1.2 | 33.2 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 1.2 | 31.6 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 1.2 | 13.2 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 1.1 | 9.9 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 1.1 | 6.5 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 1.1 | 19.2 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 1.1 | 105.2 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 1.1 | 14.7 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 1.0 | 23.0 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 1.0 | 25.0 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 1.0 | 14.4 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 1.0 | 1.9 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 1.0 | 47.4 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.9 | 29.4 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.9 | 21.6 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.9 | 21.3 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.9 | 28.1 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.9 | 21.3 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.9 | 34.7 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.9 | 9.7 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.8 | 20.0 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.8 | 11.6 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.8 | 46.9 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.8 | 34.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.8 | 24.3 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.8 | 25.8 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.8 | 12.5 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.8 | 6.8 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.8 | 115.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.7 | 21.9 | REACTOME SIGNALING BY WNT | Genes involved in Signaling by Wnt |
| 0.7 | 16.0 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.7 | 10.6 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.7 | 8.9 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.7 | 12.0 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.7 | 4.0 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.7 | 21.2 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.6 | 12.0 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 0.6 | 7.6 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.6 | 13.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.6 | 10.4 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.6 | 28.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.6 | 14.8 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.6 | 6.8 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.6 | 12.9 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.5 | 4.9 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.5 | 4.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.5 | 6.9 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.5 | 4.2 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.5 | 18.2 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.5 | 9.2 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.5 | 4.1 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 0.5 | 15.1 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.5 | 14.6 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.5 | 9.0 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.5 | 9.9 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.5 | 7.9 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.5 | 6.2 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.5 | 39.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.5 | 12.8 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.5 | 8.5 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.5 | 14.0 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.5 | 31.9 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.5 | 3.2 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.4 | 6.2 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.4 | 10.3 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.4 | 3.4 | REACTOME TRAF6 MEDIATED NFKB ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.4 | 7.7 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.4 | 9.6 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.4 | 5.6 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.4 | 21.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.4 | 6.2 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.4 | 9.6 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.4 | 6.9 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.4 | 4.2 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.3 | 6.9 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.3 | 4.0 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.3 | 6.7 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.3 | 5.3 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.3 | 7.7 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.3 | 2.5 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.3 | 10.8 | REACTOME TCR SIGNALING | Genes involved in TCR signaling |
| 0.3 | 6.8 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.3 | 7.0 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 4.2 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 0.2 | 5.6 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.2 | 2.9 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.2 | 3.6 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.2 | 4.3 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.2 | 3.4 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 3.2 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.2 | 7.5 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.2 | 7.1 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.2 | 1.4 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.2 | 7.1 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 0.7 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 2.4 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.1 | 10.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 3.7 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 0.9 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.1 | 5.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 2.5 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.1 | 2.0 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 2.1 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 1.9 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 1.0 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 1.3 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 1.5 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 0.8 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 7.8 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 0.7 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 1.5 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 1.1 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.5 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.8 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.8 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.5 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.4 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |