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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZNF333

Z-value: 2.73

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Transcription factors associated with ZNF333

Gene Symbol Gene ID Gene Info
ZNF333
ENSG00000160961.12 ZNF333

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF333hg38_v1_chr19_+_14690037_146901050.135.6e-02Click!

Activity profile of ZNF333 motif

Sorted Z-values of ZNF333 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF333

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_200440649 25.30 ENST00000366118.2
SPATS2L
spermatogenesis associated serine rich 2 like
chr6_+_29301701 8.22 ENST00000641895.1
OR14J1
olfactory receptor family 14 subfamily J member 1
chr4_-_46909235 7.51 ENST00000505102.1
ENST00000355591.8
COX7B2
cytochrome c oxidase subunit 7B2
chr4_-_46909206 7.32 ENST00000396533.5
COX7B2
cytochrome c oxidase subunit 7B2
chr18_+_74148508 6.61 ENST00000580087.5
ENST00000169551.11
TIMM21
translocase of inner mitochondrial membrane 21
chr19_+_44905785 6.33 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
APOE
apolipoprotein E
chr7_-_116030735 5.77 ENST00000393485.5
TFEC
transcription factor EC
chr5_+_157743703 5.31 ENST00000286307.6
LSM11
LSM11, U7 small nuclear RNA associated
chr1_+_19312341 5.07 ENST00000400548.6
SLC66A1
solute carrier family 66 member 1
chr6_+_131573219 5.00 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
ARG1
arginase 1
chr11_-_5249836 4.92 ENST00000632727.1
ENST00000330597.5
HBG1
hemoglobin subunit gamma 1
chr3_-_42875871 4.87 ENST00000316161.6
ENST00000437102.1
CYP8B1
cytochrome P450 family 8 subfamily B member 1
chr7_-_116030750 4.85 ENST00000265440.12
ENST00000320239.11
TFEC
transcription factor EC
chr16_+_84294823 4.55 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr1_+_248231417 4.46 ENST00000641868.1
OR2M4
olfactory receptor family 2 subfamily M member 4
chr1_+_19312296 4.44 ENST00000375155.7
ENST00000375153.8
SLC66A1
solute carrier family 66 member 1
chr12_-_70637405 4.30 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
PTPRB
protein tyrosine phosphatase receptor type B
chr16_+_84294853 4.25 ENST00000219454.10
WFDC1
WAP four-disulfide core domain 1
chr5_+_137889469 4.21 ENST00000290431.5
PKD2L2
polycystin 2 like 2, transient receptor potential cation channel
chr3_+_35679614 4.11 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
ARPP21
cAMP regulated phosphoprotein 21
chr7_-_83649097 4.03 ENST00000643230.2
SEMA3E
semaphorin 3E
chr2_-_127220293 3.91 ENST00000664447.2
ENST00000409327.2
CYP27C1
cytochrome P450 family 27 subfamily C member 1
chr9_-_94593810 3.84 ENST00000375337.4
FBP2
fructose-bisphosphatase 2
chr5_+_73626158 3.77 ENST00000296794.10
ENST00000545377.5
ENST00000509848.5
ENST00000513042.7
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr12_+_112125531 3.71 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chrX_-_19970298 3.67 ENST00000379687.7
ENST00000379682.8
BCLAF3
BCLAF1 and THRAP3 family member 3
chr9_-_107489754 3.66 ENST00000610832.1
ENST00000374672.5
KLF4
Kruppel like factor 4
chr14_+_20110739 3.64 ENST00000641386.2
ENST00000641633.2
OR4K17
olfactory receptor family 4 subfamily K member 17
chr7_+_29122274 3.33 ENST00000582692.2
ENST00000644824.1
ENSG00000285412.1
ENSG00000285162.1
novel transcript, antisense to CPVL
chimerin 2
chr19_-_44500503 3.21 ENST00000587047.1
ENST00000391956.8
ENST00000221327.8
ENST00000592529.6
ENST00000591064.1
ZNF180
zinc finger protein 180
chrX_-_30577759 3.10 ENST00000378962.4
TASL
TLR adaptor interacting with endolysosomal SLC15A4
chr3_+_196867856 3.05 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SENP5
SUMO specific peptidase 5
chr20_+_59940362 3.03 ENST00000360816.8
FAM217B
family with sequence similarity 217 member B
chr5_+_141421064 2.96 ENST00000518882.2
PCDHGA11
protocadherin gamma subfamily A, 11
chr3_+_48241046 2.91 ENST00000427617.6
ENST00000412564.5
ENST00000354698.8
ENST00000440261.6
ZNF589
zinc finger protein 589
chr2_+_79185231 2.85 ENST00000466387.5
CTNNA2
catenin alpha 2
chr20_-_45972171 2.81 ENST00000322927.3
ZNF335
zinc finger protein 335
chr9_-_111036207 2.76 ENST00000541779.5
LPAR1
lysophosphatidic acid receptor 1
chr8_+_18391276 2.76 ENST00000286479.4
ENST00000520116.1
NAT2
N-acetyltransferase 2
chr5_+_137889437 2.74 ENST00000508638.5
ENST00000508883.6
ENST00000502810.5
PKD2L2
polycystin 2 like 2, transient receptor potential cation channel
chr9_-_19786928 2.71 ENST00000341998.6
ENST00000286344.3
SLC24A2
solute carrier family 24 member 2
chr3_+_38282294 2.66 ENST00000466887.5
ENST00000448498.6
SLC22A14
solute carrier family 22 member 14
chr1_+_196888014 2.66 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
CFHR4
complement factor H related 4
chr2_-_177888728 2.57 ENST00000389683.7
PDE11A
phosphodiesterase 11A
chr6_+_50818701 2.55 ENST00000344788.7
TFAP2B
transcription factor AP-2 beta
chr5_+_140827950 2.54 ENST00000378126.4
ENST00000529310.6
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chrX_+_11293411 2.43 ENST00000348912.4
ENST00000380714.7
ENST00000380712.7
AMELX
amelogenin X-linked
chrX_-_21758021 2.40 ENST00000646008.1
SMPX
small muscle protein X-linked
chrX_-_21758097 2.40 ENST00000379494.4
SMPX
small muscle protein X-linked
chr11_-_14971179 2.34 ENST00000486207.5
CALCA
calcitonin related polypeptide alpha
chr10_-_67665642 2.30 ENST00000682945.1
ENST00000330298.6
ENST00000682758.1
CTNNA3
catenin alpha 3
chr8_-_30912998 2.27 ENST00000643185.2
TEX15
testis expressed 15, meiosis and synapsis associated
chr6_-_32941018 2.14 ENST00000418107.3
HLA-DMB
major histocompatibility complex, class II, DM beta
chr5_-_78985249 2.10 ENST00000565165.2
ARSB
arylsulfatase B
chr6_+_29585121 2.02 ENST00000641840.1
OR2H2
olfactory receptor family 2 subfamily H member 2
chr17_-_3433841 2.01 ENST00000248384.1
OR1E2
olfactory receptor family 1 subfamily E member 2
chr9_+_32551670 2.00 ENST00000450093.3
SMIM27
small integral membrane protein 27
chr2_+_29113989 1.78 ENST00000404424.5
CLIP4
CAP-Gly domain containing linker protein family member 4
chr14_+_20768393 1.75 ENST00000326783.4
EDDM3B
epididymal protein 3B
chr5_+_141421020 1.75 ENST00000622044.1
ENST00000398587.7
PCDHGA11
protocadherin gamma subfamily A, 11
chr11_+_18412292 1.75 ENST00000541669.6
ENST00000280704.8
LDHC
lactate dehydrogenase C
chr6_+_50818857 1.70 ENST00000393655.4
TFAP2B
transcription factor AP-2 beta
chr7_+_144069811 1.64 ENST00000641663.1
OR2A25
olfactory receptor family 2 subfamily A member 25
chr14_+_85530163 1.63 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr2_+_232662733 1.59 ENST00000410095.5
ENST00000611312.1
EFHD1
EF-hand domain family member D1
chr14_+_85530127 1.58 ENST00000330753.6
FLRT2
fibronectin leucine rich transmembrane protein 2
chr7_-_80512041 1.56 ENST00000398291.4
GNAT3
G protein subunit alpha transducin 3
chr14_+_23372809 1.50 ENST00000397242.2
ENST00000329715.2
IL25
interleukin 25
chr2_-_2331336 1.49 ENST00000648933.1
ENST00000644820.1
MYT1L
myelin transcription factor 1 like
chr1_+_213987929 1.49 ENST00000498508.6
ENST00000366958.9
PROX1
prospero homeobox 1
chr12_-_48999363 1.36 ENST00000421952.3
DDN
dendrin
chr17_-_3127551 1.31 ENST00000328890.3
OR1G1
olfactory receptor family 1 subfamily G member 1
chr6_+_131135408 1.31 ENST00000431975.7
ENST00000683794.1
AKAP7
A-kinase anchoring protein 7
chr4_+_70242583 1.30 ENST00000304954.3
CSN3
casein kappa
chr11_+_33039996 1.24 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
TCP11L1
t-complex 11 like 1
chrX_+_100584928 1.23 ENST00000373031.5
TNMD
tenomodulin
chr3_-_114199407 1.20 ENST00000460779.5
DRD3
dopamine receptor D3
chr4_+_105552611 1.20 ENST00000265154.6
ENST00000420470.3
ARHGEF38
Rho guanine nucleotide exchange factor 38
chr16_-_20691256 1.09 ENST00000307493.8
ACSM1
acyl-CoA synthetase medium chain family member 1
chrX_-_70260199 1.02 ENST00000374519.4
P2RY4
pyrimidinergic receptor P2Y4
chr5_-_16508951 1.00 ENST00000682628.1
RETREG1
reticulophagy regulator 1
chr1_-_169630115 1.00 ENST00000263686.11
ENST00000367788.6
SELP
selectin P
chr5_-_16508858 0.98 ENST00000684456.1
RETREG1
reticulophagy regulator 1
chr5_-_16508812 0.96 ENST00000683414.1
RETREG1
reticulophagy regulator 1
chr20_+_45207025 0.95 ENST00000372781.4
SEMG1
semenogelin 1
chr1_+_54548217 0.94 ENST00000343744.7
ENST00000371316.3
ACOT11
acyl-CoA thioesterase 11
chr4_+_69931066 0.93 ENST00000246891.9
CSN1S1
casein alpha s1
chrX_-_49264668 0.93 ENST00000455775.7
ENST00000652559.1
ENST00000376207.10
ENST00000557224.6
ENST00000684155.1
ENST00000376199.7
FOXP3
forkhead box P3
chr4_+_109827963 0.82 ENST00000317735.7
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr12_-_7695752 0.80 ENST00000329913.4
GDF3
growth differentiation factor 3
chr2_+_102311502 0.69 ENST00000404917.6
ENST00000410040.5
IL1RL1
IL18R1
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr18_+_48539017 0.67 ENST00000256413.8
CTIF
cap binding complex dependent translation initiation factor
chr5_-_27038576 0.65 ENST00000511822.1
ENST00000231021.9
CDH9
cadherin 9
chr2_-_144517663 0.60 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
ZEB2
zinc finger E-box binding homeobox 2
chr5_-_147782518 0.51 ENST00000507386.5
JAKMIP2
janus kinase and microtubule interacting protein 2
chr3_-_116444983 0.51 ENST00000333617.8
LSAMP
limbic system associated membrane protein
chr2_+_216498831 0.45 ENST00000491306.6
ENST00000600880.5
ENST00000446558.5
RPL37A
ribosomal protein L37a
chr1_-_27374816 0.44 ENST00000270879.9
ENST00000354982.2
FCN3
ficolin 3
chr2_+_88885397 0.41 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr12_-_10807286 0.38 ENST00000240615.3
TAS2R8
taste 2 receptor member 8
chr1_+_59297057 0.38 ENST00000303721.12
FGGY
FGGY carbohydrate kinase domain containing
chr1_+_159439722 0.36 ENST00000641630.1
ENST00000423932.6
OR10J1
olfactory receptor family 10 subfamily J member 1
chr1_-_51297990 0.24 ENST00000530004.5
TTC39A
tetratricopeptide repeat domain 39A
chr11_-_72793592 0.24 ENST00000536377.5
ENST00000359373.9
STARD10
ARAP1
StAR related lipid transfer domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr14_+_23630109 0.23 ENST00000432832.6
DHRS2
dehydrogenase/reductase 2
chr10_-_121596117 0.14 ENST00000351936.11
FGFR2
fibroblast growth factor receptor 2
chr12_+_59664677 0.14 ENST00000548610.5
SLC16A7
solute carrier family 16 member 7
chr8_+_127409026 0.14 ENST00000465342.4
POU5F1B
POU class 5 homeobox 1B
chr7_-_25228485 0.12 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr13_-_71867192 0.11 ENST00000611519.4
ENST00000620444.4
ENST00000613252.5
DACH1
dachshund family transcription factor 1
chr5_-_78985288 0.09 ENST00000264914.10
ARSB
arylsulfatase B
chr1_-_197067234 0.08 ENST00000367412.2
F13B
coagulation factor XIII B chain
chr8_+_40153475 0.07 ENST00000315792.5
TCIM
transcriptional and immune response regulator
chr17_-_35119733 0.06 ENST00000460118.6
ENST00000335858.11
RAD51D
RAD51 paralog D
chr2_-_213151590 0.04 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKZF2
IKAROS family zinc finger 2
chrX_-_120311533 0.02 ENST00000440464.5
ENST00000519908.1
TMEM255A
transmembrane protein 255A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0097272 ammonia homeostasis(GO:0097272)
1.3 6.3 GO:1902952 positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of dendritic spine maintenance(GO:1902952)
1.3 5.0 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
1.2 3.7 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
1.0 3.8 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.9 5.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.8 2.3 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.7 2.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.6 2.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.5 2.2 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.5 3.1 GO:0016926 protein desumoylation(GO:0016926)
0.5 6.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.5 1.5 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.4 1.7 GO:0019249 lactate biosynthetic process(GO:0019249)
0.4 2.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.4 0.8 GO:0048859 formation of anatomical boundary(GO:0048859)
0.4 1.6 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.4 1.1 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4 3.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 2.6 GO:0061709 reticulophagy(GO:0061709)
0.3 0.9 GO:0032829 tolerance induction dependent upon immune response(GO:0002461) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of immature T cell proliferation(GO:0033091)
0.3 1.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.3 2.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.3 2.8 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.3 3.9 GO:0042574 retinal metabolic process(GO:0042574)
0.3 4.9 GO:0015671 oxygen transport(GO:0015671)
0.3 1.5 GO:0009624 response to nematode(GO:0009624)
0.2 1.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 23.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 2.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 0.9 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 6.9 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 13.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 2.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 4.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 4.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.7 GO:0071351 negative regulation of T-helper 1 type immune response(GO:0002826) interleukin-18-mediated signaling pathway(GO:0035655) interleukin-33-mediated signaling pathway(GO:0038172) cellular response to interleukin-18(GO:0071351)
0.1 1.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 2.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 8.8 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 2.7 GO:0015695 organic cation transport(GO:0015695)
0.1 0.6 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 14.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 2.7 GO:0060292 long term synaptic depression(GO:0060292)
0.1 3.5 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) bile acid secretion(GO:0032782)
0.1 2.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 7.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 5.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 3.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 2.6 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.9 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 1.3 GO:0007595 lactation(GO:0007595)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.9 14.8 GO:0045277 respiratory chain complex IV(GO:0045277)
0.8 4.8 GO:0005927 muscle tendon junction(GO:0005927)
0.8 5.3 GO:0005683 U7 snRNP(GO:0005683)
0.5 6.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 4.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 2.3 GO:0005916 fascia adherens(GO:0005916)
0.1 3.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 7.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 2.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 2.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 2.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.3 GO:0043195 terminal bouton(GO:0043195)
0.0 2.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.7 GO:0031514 motile cilium(GO:0031514)
0.0 5.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
1.3 3.9 GO:0005502 11-cis retinal binding(GO:0005502)
1.0 3.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.9 2.8 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.8 8.2 GO:0005549 odorant binding(GO:0005549)
0.8 2.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.7 3.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.7 2.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.6 2.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.5 3.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.5 14.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 2.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 5.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 1.0 GO:0042806 fucose binding(GO:0042806)
0.3 4.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 2.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 2.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 4.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.7 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2 0.7 GO:0002113 interleukin-33 binding(GO:0002113) interleukin-18 receptor activity(GO:0042008)
0.2 2.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 15.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 3.2 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1 1.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 2.7 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 1.0 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 4.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 1.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 4.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 3.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 5.3 GO:0017069 snRNA binding(GO:0017069)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 8.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 6.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 1.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 5.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 10.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 2.7 GO:0005319 lipid transporter activity(GO:0005319)
0.0 5.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 4.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID CONE PATHWAY Visual signal transduction: Cones
0.1 10.6 PID CMYB PATHWAY C-MYB transcription factor network
0.1 6.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 4.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 5.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 6.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 21.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 3.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 2.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 4.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.8 REACTOME OPSINS Genes involved in Opsins
0.1 2.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 3.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 2.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation