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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZNF350

Z-value: 1.20

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.7 ZNF350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg38_v1_chr19_-_51986670_519868590.202.4e-03Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_46831134 7.00 ENST00000394806.6
ENST00000285697.9
C16orf87
chromosome 16 open reading frame 87
chr6_+_11537738 6.85 ENST00000379426.2
TMEM170B
transmembrane protein 170B
chr11_-_63614425 5.98 ENST00000415826.3
PLAAT3
phospholipase A and acyltransferase 3
chr11_-_63614366 5.92 ENST00000323646.9
PLAAT3
phospholipase A and acyltransferase 3
chr2_+_241702027 5.48 ENST00000313552.11
ENST00000406941.5
ING5
inhibitor of growth family member 5
chr17_-_19046957 4.07 ENST00000284154.10
ENST00000573099.5
GRAP
GRB2 related adaptor protein
chr2_+_232633551 3.86 ENST00000264059.8
EFHD1
EF-hand domain family member D1
chr13_+_49628489 3.38 ENST00000282026.2
ARL11
ADP ribosylation factor like GTPase 11
chr5_-_16617085 3.27 ENST00000684521.1
RETREG1
reticulophagy regulator 1
chr9_+_129665603 3.25 ENST00000372469.6
PRRX2
paired related homeobox 2
chr3_-_51968387 3.23 ENST00000490063.5
ENST00000468324.5
ENST00000497653.5
ENST00000484633.5
PCBP4
poly(rC) binding protein 4
chr2_-_156342348 2.97 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr5_-_16616972 2.53 ENST00000682564.1
ENST00000306320.10
ENST00000682229.1
RETREG1
reticulophagy regulator 1
chr12_+_112938284 2.42 ENST00000681346.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr11_+_706196 2.33 ENST00000534755.5
ENST00000650127.1
EPS8L2
EPS8 like 2
chr20_+_45406560 2.32 ENST00000372717.5
ENST00000360981.8
DBNDD2
dysbindin domain containing 2
chr19_+_49363074 2.32 ENST00000597873.5
DKKL1
dickkopf like acrosomal protein 1
chr19_-_5680488 2.29 ENST00000587589.1
ENST00000309324.9
MICOS13
mitochondrial contact site and cristae organizing system subunit 13
chr12_+_6914571 2.27 ENST00000229277.6
ENST00000538763.5
ENST00000545045.6
ENO2
enolase 2
chr11_+_706222 2.27 ENST00000318562.13
ENST00000533500.5
EPS8L2
EPS8 like 2
chr12_+_112938422 2.26 ENST00000680044.1
ENST00000680966.1
ENST00000548514.2
ENST00000681497.1
ENST00000551007.1
ENST00000228928.12
ENST00000680438.1
ENST00000681147.1
ENST00000679354.1
ENST00000681085.1
ENST00000680161.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr19_+_5681000 2.25 ENST00000581893.5
ENST00000411793.6
ENST00000301382.8
ENST00000581773.5
ENST00000339423.7
ENST00000423665.6
ENST00000583928.5
ENST00000342970.6
ENST00000422535.6
ENST00000581521.5
HSD11B1L
hydroxysteroid 11-beta dehydrogenase 1 like
chr19_+_2977538 2.23 ENST00000453329.5
ENST00000482627.1
ENST00000246112.9
ENST00000452088.5
TLE6
TLE family member 6, subcortical maternal complex member
chr12_+_112938523 2.17 ENST00000679483.1
ENST00000679493.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr3_-_14178569 2.15 ENST00000285021.12
XPC
XPC complex subunit, DNA damage recognition and repair factor
chr11_-_64744317 2.14 ENST00000419843.1
ENST00000394430.5
RASGRP2
RAS guanyl releasing protein 2
chr15_-_42737054 2.08 ENST00000563260.1
ENST00000356231.4
CDAN1
codanin 1
chr7_+_2519763 1.99 ENST00000222725.10
ENST00000359574.7
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_+_706117 1.96 ENST00000533256.5
ENST00000614442.4
EPS8L2
EPS8 like 2
chr16_+_69566314 1.84 ENST00000565301.2
NFAT5
nuclear factor of activated T cells 5
chr18_-_59697637 1.80 ENST00000649564.1
CCBE1
collagen and calcium binding EGF domains 1
chr5_-_784691 1.73 ENST00000508859.8
ENST00000652055.1
ENST00000651083.1
ZDHHC11B
zinc finger DHHC-type containing 11B
chr6_-_56843153 1.72 ENST00000361203.7
ENST00000523817.1
DST
dystonin
chr1_-_200410001 1.71 ENST00000367353.2
ZNF281
zinc finger protein 281
chr17_+_50547089 1.70 ENST00000619622.4
ENST00000356488.8
ENST00000006658.11
SPATA20
spermatogenesis associated 20
chr11_-_112164080 1.68 ENST00000528832.1
ENST00000280357.12
IL18
interleukin 18
chr18_-_59697220 1.60 ENST00000650467.1
ENST00000439986.9
CCBE1
collagen and calcium binding EGF domains 1
chr12_-_47079926 1.58 ENST00000429635.1
ENST00000550413.2
AMIGO2
adhesion molecule with Ig like domain 2
chr11_-_112164056 1.58 ENST00000524595.5
IL18
interleukin 18
chr16_+_31214111 1.58 ENST00000322122.8
TRIM72
tripartite motif containing 72
chr12_-_47079859 1.53 ENST00000266581.4
AMIGO2
adhesion molecule with Ig like domain 2
chr12_+_55932028 1.52 ENST00000394147.5
ENST00000551156.5
ENST00000553783.5
ENST00000557080.5
ENST00000432422.7
ENST00000556001.5
DGKA
diacylglycerol kinase alpha
chr1_-_200410052 1.51 ENST00000294740.3
ZNF281
zinc finger protein 281
chr20_-_36746053 1.46 ENST00000373803.6
ENST00000359675.6
ENST00000349004.6
NDRG3
NDRG family member 3
chr11_+_118956289 1.45 ENST00000264031.3
UPK2
uroplakin 2
chr2_-_70553638 1.40 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
TGFA
transforming growth factor alpha
chr17_+_70075317 1.40 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr17_+_70075215 1.38 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr17_-_76453142 1.36 ENST00000319380.12
UBE2O
ubiquitin conjugating enzyme E2 O
chr10_-_77637789 1.35 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr20_+_63736651 1.30 ENST00000487026.5
ENST00000309546.8
ENST00000480139.5
LIME1
Lck interacting transmembrane adaptor 1
chr2_-_9003657 1.28 ENST00000462696.1
ENST00000305997.8
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr1_+_156642108 1.27 ENST00000457777.6
ENST00000329117.10
ENST00000424639.5
BCAN
brevican
chr17_-_6651557 1.27 ENST00000225728.8
ENST00000575197.1
MED31
mediator complex subunit 31
chr20_+_4686320 1.26 ENST00000430350.2
PRNP
prion protein
chr1_+_19664859 1.25 ENST00000289753.2
HTR6
5-hydroxytryptamine receptor 6
chr20_+_4686448 1.25 ENST00000379440.9
ENST00000424424.2
ENST00000457586.2
PRNP
prion protein
chr22_+_50600783 1.24 ENST00000329492.6
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr8_-_42843201 1.19 ENST00000529779.1
ENST00000345117.2
ENST00000254250.7
THAP1
THAP domain containing 1
chr17_+_2337622 1.13 ENST00000574563.5
SGSM2
small G protein signaling modulator 2
chr9_-_95509241 1.11 ENST00000331920.11
PTCH1
patched 1
chr11_+_33376077 1.04 ENST00000658780.2
KIAA1549L
KIAA1549 like
chr1_-_200409976 1.03 ENST00000367352.3
ZNF281
zinc finger protein 281
chr12_+_81078035 1.00 ENST00000261206.7
ENST00000548058.6
ACSS3
acyl-CoA synthetase short chain family member 3
chr12_+_93378625 0.99 ENST00000546925.1
NUDT4
nudix hydrolase 4
chr17_+_2337480 0.95 ENST00000268989.8
ENST00000426855.6
SGSM2
small G protein signaling modulator 2
chr6_-_28336123 0.94 ENST00000439158.5
ENST00000446474.5
ENST00000414431.1
ENST00000344279.11
ENST00000453745.5
ZSCAN31
zinc finger and SCAN domain containing 31
chr11_-_45665578 0.94 ENST00000308064.7
CHST1
carbohydrate sulfotransferase 1
chr5_+_7396099 0.91 ENST00000338316.9
ADCY2
adenylate cyclase 2
chr5_-_93741587 0.91 ENST00000606183.4
POU5F2
POU domain class 5, transcription factor 2
chr11_+_64555956 0.91 ENST00000377581.7
SLC22A11
solute carrier family 22 member 11
chr19_+_1450113 0.86 ENST00000590469.6
ENST00000590877.5
ENST00000233607.6
APC2
APC regulator of WNT signaling pathway 2
chr11_-_62706304 0.84 ENST00000278893.11
ENST00000407022.7
ENST00000421906.5
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr1_+_28887166 0.82 ENST00000347529.7
EPB41
erythrocyte membrane protein band 4.1
chr1_-_204685353 0.82 ENST00000367176.7
LRRN2
leucine rich repeat neuronal 2
chr11_-_62706234 0.81 ENST00000403550.5
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr1_+_156642148 0.79 ENST00000361588.5
BCAN
brevican
chr11_+_64555924 0.78 ENST00000301891.9
SLC22A11
solute carrier family 22 member 11
chr11_-_75525925 0.75 ENST00000336898.8
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr17_-_8190154 0.74 ENST00000389017.6
BORCS6
BLOC-1 related complex subunit 6
chr11_-_8932944 0.71 ENST00000326053.10
ENST00000525780.5
C11orf16
chromosome 11 open reading frame 16
chr11_+_68903849 0.70 ENST00000675615.1
ENST00000255078.8
IGHMBP2
immunoglobulin mu DNA binding protein 2
chr19_-_17377334 0.69 ENST00000252590.9
ENST00000599426.1
PLVAP
plasmalemma vesicle associated protein
chr2_+_119759875 0.67 ENST00000263708.7
PTPN4
protein tyrosine phosphatase non-receptor type 4
chr4_-_98657635 0.67 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
TSPAN5
tetraspanin 5
chr14_+_96204679 0.64 ENST00000542454.2
ENST00000539359.1
ENST00000554311.2
ENST00000553811.1
BDKRB2
ENSG00000258691.1
bradykinin receptor B2
novel protein
chr19_+_42325612 0.64 ENST00000251268.11
MEGF8
multiple EGF like domains 8
chr3_+_12287962 0.64 ENST00000643197.2
ENST00000644622.2
PPARG
peroxisome proliferator activated receptor gamma
chr12_+_8032692 0.60 ENST00000162391.8
FOXJ2
forkhead box J2
chr11_-_61920267 0.60 ENST00000531922.2
ENST00000301773.9
RAB3IL1
RAB3A interacting protein like 1
chr3_+_12287859 0.59 ENST00000309576.11
ENST00000397015.7
PPARG
peroxisome proliferator activated receptor gamma
chr2_+_202376301 0.58 ENST00000374580.10
BMPR2
bone morphogenetic protein receptor type 2
chr13_-_99086611 0.56 ENST00000427887.2
DOCK9
dedicator of cytokinesis 9
chr19_+_42325550 0.53 ENST00000334370.8
ENST00000378073.5
MEGF8
multiple EGF like domains 8
chr11_-_9091589 0.52 ENST00000649792.2
ENST00000520467.5
ENST00000309263.7
SCUBE2
signal peptide, CUB domain and EGF like domain containing 2
chr22_+_21665994 0.52 ENST00000680393.1
ENST00000679534.1
ENST00000679827.1
ENST00000681956.1
ENST00000681338.1
ENST00000680061.1
ENST00000679540.1
ENST00000679795.1
ENST00000335025.12
ENST00000398831.8
ENST00000679477.1
ENST00000626352.2
ENST00000458567.5
ENST00000680094.1
ENST00000680109.1
ENST00000406385.1
ENST00000680860.1
PPIL2
peptidylprolyl isomerase like 2
chr1_+_109249530 0.52 ENST00000271332.4
CELSR2
cadherin EGF LAG seven-pass G-type receptor 2
chr10_-_15719885 0.52 ENST00000378076.4
ITGA8
integrin subunit alpha 8
chr16_+_67248966 0.52 ENST00000299798.16
SLC9A5
solute carrier family 9 member A5
chr10_-_77090722 0.49 ENST00000638531.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr1_-_168136707 0.47 ENST00000539777.5
GPR161
G protein-coupled receptor 161
chr10_+_67884646 0.47 ENST00000212015.11
SIRT1
sirtuin 1
chr22_+_39077264 0.44 ENST00000407997.4
APOBEC3G
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
chr1_+_156150008 0.38 ENST00000355014.6
SEMA4A
semaphorin 4A
chrX_+_121047601 0.37 ENST00000328078.3
GLUD2
glutamate dehydrogenase 2
chr12_-_92929236 0.36 ENST00000322349.13
EEA1
early endosome antigen 1
chr15_+_42402375 0.35 ENST00000397200.8
ENST00000569827.5
CAPN3
calpain 3
chr3_-_45842066 0.34 ENST00000445698.1
ENST00000296135.11
LZTFL1
leucine zipper transcription factor like 1
chr4_+_74933095 0.34 ENST00000513238.5
PARM1
prostate androgen-regulated mucin-like protein 1
chr16_+_2429427 0.33 ENST00000397066.9
CCNF
cyclin F
chr12_-_113135710 0.31 ENST00000446861.7
RASAL1
RAS protein activator like 1
chr17_-_41440983 0.29 ENST00000246646.4
KRT38
keratin 38
chr11_-_64744102 0.19 ENST00000431822.5
ENST00000394432.8
ENST00000377486.7
RASGRP2
RAS guanyl releasing protein 2
chr3_+_50191604 0.13 ENST00000232461.8
ENST00000433068.5
GNAT1
G protein subunit alpha transducin 1
chr3_+_114056728 0.13 ENST00000485050.5
ENST00000281273.8
ENST00000479882.5
ENST00000493014.1
QTRT2
queuine tRNA-ribosyltransferase accessory subunit 2
chr2_-_218659468 0.12 ENST00000450560.1
ENST00000449707.5
ENST00000440934.2
ZNF142
zinc finger protein 142
chr2_-_218659592 0.12 ENST00000411696.7
ZNF142
zinc finger protein 142
chr11_+_57763820 0.09 ENST00000674106.1
CTNND1
catenin delta 1
chr1_+_43935807 0.09 ENST00000438616.3
ARTN
artemin
chr3_+_37861849 0.09 ENST00000273179.10
CTDSPL
CTD small phosphatase like
chr17_-_41812586 0.08 ENST00000355468.7
ENST00000590496.1
P3H4
prolyl 3-hydroxylase family member 4 (inactive)
chr11_-_9091546 0.08 ENST00000450649.6
SCUBE2
signal peptide, CUB domain and EGF like domain containing 2
chr16_+_4476340 0.08 ENST00000458134.7
ENST00000619528.4
ENST00000619913.4
ENST00000219700.10
ENST00000570646.6
ENST00000575120.5
ENST00000572812.5
ENST00000574466.5
ENST00000576827.5
ENST00000570445.5
HMOX2
heme oxygenase 2
chr1_-_155244645 0.07 ENST00000327247.9
GBA
glucosylceramidase beta
chr1_-_155244684 0.05 ENST00000428024.3
GBA
glucosylceramidase beta
chr19_+_2249317 0.05 ENST00000221496.5
AMH
anti-Mullerian hormone
chr1_-_246931892 0.05 ENST00000648844.2
AHCTF1
AT-hook containing transcription factor 1
chr19_-_55157725 0.02 ENST00000344887.10
ENST00000665070.1
TNNI3
troponin I3, cardiac type

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
1.1 3.3 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
1.0 3.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.7 5.8 GO:0061709 reticulophagy(GO:0061709)
0.7 2.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.6 2.5 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.6 6.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.5 5.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 2.0 GO:0007386 compartment pattern specification(GO:0007386)
0.3 1.1 GO:0010157 response to chlorate(GO:0010157)
0.2 1.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.2 2.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.2 1.7 GO:0015747 urate transport(GO:0015747)
0.2 0.6 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.2 4.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 1.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 0.5 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.2 0.5 GO:1901420 negative regulation of prostaglandin biosynthetic process(GO:0031393) negative regulation of helicase activity(GO:0051097) negative regulation of response to alcohol(GO:1901420)
0.2 1.8 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 1.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 2.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.3 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 1.2 GO:0046958 nonassociative learning(GO:0046958)
0.1 1.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 2.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.6 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 1.3 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 0.4 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.9 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 1.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 5.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.7 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 0.8 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.3 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 3.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 2.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.9 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 2.3 GO:0006735 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 1.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 4.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 1.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 2.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.3 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 3.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 1.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 2.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.7 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 2.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.4 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0071942 XPC complex(GO:0071942)
0.5 5.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 1.7 GO:0031673 H zone(GO:0031673)
0.3 2.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.3 1.3 GO:0070847 core mediator complex(GO:0070847)
0.1 0.5 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 1.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 2.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 5.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 2.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 8.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 3.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 4.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.8 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.5 2.5 GO:1903135 cupric ion binding(GO:1903135)
0.5 2.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 2.2 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.3 2.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 1.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 6.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.7 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 2.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.2 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 4.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 2.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.6 GO:0098821 BMP receptor activity(GO:0098821)
0.1 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 5.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.0 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 4.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.4 GO:0005518 collagen binding(GO:0005518)
0.0 3.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 3.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 3.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.9 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 4.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 2.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 5.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 3.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 6.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 4.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 3.4 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 3.3 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)