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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ZNF384
Z-value: 11.51
Motif logo
Transcription factors associated with ZNF384
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ZNF384
|
ENSG00000126746.18 | ZNF384 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF384 | hg38_v1_chr12_-_6689244_6689337, hg38_v1_chr12_-_6689450_6689517, hg38_v1_chr12_-_6689359_6689380 | -0.51 | 1.4e-15 | Click! |
Activity profile of ZNF384 motif
Sorted Z-values of ZNF384 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF384
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 21.7 | 86.7 | GO:0006238 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 20.0 | 60.0 | GO:0070476 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 14.0 | 42.0 | GO:1902524 | positive regulation of protein K48-linked ubiquitination(GO:1902524) |
| 13.8 | 41.4 | GO:0097698 | telomere maintenance via base-excision repair(GO:0097698) |
| 10.9 | 32.8 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 10.5 | 31.4 | GO:0036292 | DNA rewinding(GO:0036292) |
| 10.4 | 31.1 | GO:1901388 | regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389) |
| 9.3 | 37.1 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 9.3 | 129.5 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 9.2 | 46.2 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 8.1 | 24.2 | GO:0036111 | very long-chain fatty-acyl-CoA metabolic process(GO:0036111) |
| 8.0 | 32.1 | GO:0009137 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 8.0 | 32.0 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 7.5 | 22.6 | GO:0002368 | B cell cytokine production(GO:0002368) |
| 7.5 | 97.6 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 7.4 | 22.3 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 7.4 | 22.1 | GO:0071314 | cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 7.2 | 7.2 | GO:0009146 | purine nucleoside triphosphate catabolic process(GO:0009146) |
| 7.2 | 28.7 | GO:0051257 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 6.7 | 27.0 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
| 6.7 | 20.2 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 6.5 | 39.0 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 6.4 | 38.3 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 6.3 | 87.8 | GO:1904869 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 6.2 | 43.6 | GO:0046985 | histone H4-R3 methylation(GO:0043985) positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 6.2 | 24.9 | GO:0000915 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 6.2 | 18.7 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 6.0 | 6.0 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 6.0 | 24.0 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 6.0 | 17.9 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 5.9 | 23.5 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 5.9 | 46.8 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 5.7 | 17.0 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 5.6 | 5.6 | GO:0010482 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 5.5 | 16.6 | GO:1904430 | negative regulation of t-circle formation(GO:1904430) |
| 5.5 | 27.6 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 5.5 | 32.9 | GO:0032383 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 5.5 | 16.4 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 5.4 | 16.3 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 5.4 | 32.6 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 5.4 | 5.4 | GO:0030423 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) |
| 5.2 | 15.6 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 5.1 | 15.4 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 5.1 | 15.3 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 5.0 | 15.1 | GO:0010994 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 5.0 | 55.2 | GO:0042262 | DNA protection(GO:0042262) |
| 5.0 | 54.9 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 5.0 | 14.9 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 4.9 | 14.8 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 4.9 | 14.7 | GO:0051793 | medium-chain fatty acid catabolic process(GO:0051793) |
| 4.9 | 29.4 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 4.9 | 14.7 | GO:2000521 | negative regulation of immunological synapse formation(GO:2000521) |
| 4.8 | 48.5 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 4.8 | 28.5 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 4.7 | 23.3 | GO:1903588 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 4.6 | 18.6 | GO:0044571 | [2Fe-2S] cluster assembly(GO:0044571) |
| 4.6 | 46.0 | GO:1904874 | positive regulation of telomerase RNA localization to Cajal body(GO:1904874) |
| 4.5 | 18.1 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 4.2 | 12.6 | GO:0009149 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081) |
| 4.2 | 29.3 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 4.2 | 4.2 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 4.1 | 12.3 | GO:0097069 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 4.1 | 20.4 | GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) |
| 4.0 | 190.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 4.0 | 16.1 | GO:2001248 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
| 4.0 | 72.1 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 4.0 | 11.9 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
| 4.0 | 27.7 | GO:0015866 | ADP transport(GO:0015866) |
| 3.9 | 11.8 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 3.9 | 7.8 | GO:0044211 | CTP salvage(GO:0044211) |
| 3.9 | 11.6 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 3.8 | 34.4 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 3.8 | 129.5 | GO:0031055 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 3.8 | 37.5 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 3.7 | 22.4 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 3.7 | 3.7 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 3.7 | 11.1 | GO:0070602 | regulation of centromeric sister chromatid cohesion(GO:0070602) |
| 3.6 | 32.7 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 3.6 | 32.0 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 3.6 | 28.4 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 3.5 | 21.2 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 3.5 | 14.1 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 3.5 | 24.5 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 3.5 | 10.4 | GO:0060739 | mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739) |
| 3.4 | 20.6 | GO:0006222 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
| 3.4 | 17.1 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 3.4 | 27.1 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
| 3.3 | 56.7 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 3.3 | 39.7 | GO:0009414 | response to water deprivation(GO:0009414) |
| 3.3 | 29.8 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 3.3 | 9.9 | GO:0034238 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) |
| 3.2 | 6.5 | GO:0097327 | response to antineoplastic agent(GO:0097327) |
| 3.2 | 9.6 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 3.2 | 25.3 | GO:0030473 | nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) |
| 3.1 | 24.8 | GO:1902969 | mitotic DNA replication(GO:1902969) |
| 3.1 | 18.6 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 3.1 | 9.2 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 3.0 | 12.1 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 3.0 | 57.0 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 3.0 | 29.8 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 3.0 | 26.8 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 3.0 | 8.9 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 2.9 | 17.7 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 2.9 | 11.7 | GO:0043380 | regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) |
| 2.9 | 11.6 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 2.9 | 11.6 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 2.9 | 23.0 | GO:0051343 | positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343) |
| 2.8 | 5.7 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 2.8 | 19.6 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 2.8 | 19.6 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 2.8 | 16.7 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 2.8 | 19.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 2.8 | 16.7 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 2.8 | 22.0 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 2.7 | 35.1 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 2.7 | 18.9 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 2.7 | 26.9 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 2.7 | 10.7 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 2.7 | 10.7 | GO:1904504 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 2.7 | 18.7 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 2.6 | 21.1 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 2.6 | 10.5 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 2.6 | 10.5 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 2.6 | 7.9 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 2.6 | 7.9 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 2.6 | 67.7 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 2.6 | 20.7 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 2.5 | 20.4 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 2.5 | 63.3 | GO:0071173 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 2.5 | 7.6 | GO:2000224 | sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224) |
| 2.5 | 57.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 2.5 | 10.0 | GO:1904117 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 2.5 | 9.9 | GO:0090095 | metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 2.5 | 22.2 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 2.4 | 14.2 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 2.4 | 7.1 | GO:0060599 | cardiac right atrium morphogenesis(GO:0003213) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) regulation of cell proliferation in midbrain(GO:1904933) |
| 2.3 | 13.9 | GO:0030581 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 2.3 | 222.0 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 2.3 | 6.9 | GO:0061290 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 2.3 | 20.6 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 2.3 | 6.8 | GO:2000360 | negative regulation of binding of sperm to zona pellucida(GO:2000360) |
| 2.3 | 24.8 | GO:0032905 | transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 2.3 | 42.8 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 2.2 | 31.4 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 2.2 | 8.9 | GO:1904045 | cellular response to aldosterone(GO:1904045) |
| 2.2 | 13.3 | GO:0019255 | UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255) UDP-glucuronate metabolic process(GO:0046398) |
| 2.2 | 6.6 | GO:0033168 | conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404) |
| 2.2 | 35.0 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 2.2 | 8.8 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 2.2 | 8.7 | GO:0018032 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 2.2 | 6.5 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 2.1 | 12.7 | GO:0009211 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 2.1 | 40.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 2.1 | 10.5 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
| 2.1 | 14.6 | GO:1901977 | negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002) |
| 2.1 | 14.5 | GO:0050689 | negative regulation of defense response to virus by host(GO:0050689) |
| 2.1 | 22.6 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 2.1 | 14.4 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 2.0 | 22.5 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 2.0 | 6.1 | GO:1901805 | beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457) |
| 2.0 | 20.3 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 2.0 | 8.1 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 2.0 | 12.1 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 2.0 | 10.0 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 2.0 | 6.0 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 2.0 | 8.0 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 2.0 | 28.0 | GO:0006983 | ER overload response(GO:0006983) |
| 2.0 | 21.8 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 2.0 | 7.9 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 2.0 | 3.9 | GO:0033048 | negative regulation of mitotic sister chromatid segregation(GO:0033048) |
| 2.0 | 5.9 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 2.0 | 11.8 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 1.9 | 35.1 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 1.9 | 7.8 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 1.9 | 9.7 | GO:0030952 | establishment or maintenance of cytoskeleton polarity(GO:0030952) |
| 1.9 | 7.7 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 1.9 | 15.3 | GO:2000582 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 1.9 | 7.7 | GO:1903173 | phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173) |
| 1.9 | 9.5 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 1.9 | 5.6 | GO:0034553 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
| 1.9 | 9.4 | GO:1904354 | negative regulation of telomere capping(GO:1904354) |
| 1.8 | 20.3 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 1.8 | 40.5 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 1.8 | 29.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 1.8 | 7.3 | GO:1904977 | lymphatic endothelial cell migration(GO:1904977) |
| 1.8 | 23.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 1.8 | 8.9 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 1.8 | 5.3 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
| 1.8 | 65.6 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 1.8 | 7.1 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 1.8 | 15.9 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 1.8 | 12.3 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
| 1.8 | 5.3 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
| 1.7 | 10.5 | GO:0097338 | response to clozapine(GO:0097338) |
| 1.7 | 8.7 | GO:1903904 | negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107) |
| 1.7 | 10.4 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
| 1.7 | 5.1 | GO:2000706 | amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798) |
| 1.7 | 10.1 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
| 1.7 | 6.7 | GO:0051030 | snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833) snRNA transport(GO:0051030) |
| 1.7 | 25.0 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 1.6 | 16.2 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 1.6 | 25.8 | GO:2000641 | regulation of early endosome to late endosome transport(GO:2000641) |
| 1.6 | 8.0 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 1.6 | 4.8 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 1.6 | 6.4 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 1.6 | 3.2 | GO:0070495 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 1.6 | 23.7 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 1.6 | 7.9 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 1.6 | 12.6 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 1.6 | 22.0 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
| 1.6 | 6.3 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.6 | 29.6 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 1.6 | 7.8 | GO:0003068 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 1.5 | 6.2 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 1.5 | 55.4 | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) |
| 1.5 | 15.4 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 1.5 | 108.8 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 1.5 | 21.3 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 1.5 | 4.6 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 1.5 | 27.2 | GO:0043981 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 1.5 | 4.5 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 1.5 | 76.8 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 1.5 | 19.6 | GO:1900625 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 1.5 | 7.5 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 1.5 | 23.8 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 1.5 | 4.5 | GO:0090176 | microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176) |
| 1.5 | 8.9 | GO:1904429 | meiotic mismatch repair(GO:0000710) pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) regulation of t-circle formation(GO:1904429) positive regulation of t-circle formation(GO:1904431) |
| 1.5 | 14.7 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 1.5 | 58.7 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 1.5 | 5.9 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
| 1.5 | 16.1 | GO:0042407 | cristae formation(GO:0042407) |
| 1.5 | 1.5 | GO:0060056 | mammary gland involution(GO:0060056) |
| 1.4 | 11.6 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 1.4 | 2.9 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 1.4 | 4.3 | GO:1904732 | regulation of electron carrier activity(GO:1904732) |
| 1.4 | 31.4 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 1.4 | 8.6 | GO:0008204 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 1.4 | 10.0 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 1.4 | 11.3 | GO:0072733 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 1.4 | 5.6 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 1.4 | 8.3 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 1.4 | 4.1 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 1.3 | 14.8 | GO:0000478 | endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 1.3 | 4.0 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 1.3 | 4.0 | GO:0061573 | endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650) |
| 1.3 | 9.3 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 1.3 | 5.2 | GO:0035803 | egg coat formation(GO:0035803) |
| 1.3 | 5.2 | GO:0042996 | regulation of Golgi to plasma membrane protein transport(GO:0042996) |
| 1.3 | 5.2 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 1.3 | 5.2 | GO:0016334 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 1.3 | 9.0 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 1.3 | 24.4 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 1.3 | 38.4 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 1.3 | 3.8 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 1.3 | 5.1 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 1.3 | 2.5 | GO:1902661 | negative regulation of histone H3-K9 dimethylation(GO:1900110) positive regulation of glucose mediated signaling pathway(GO:1902661) |
| 1.2 | 19.9 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 1.2 | 77.9 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 1.2 | 2.5 | GO:0001545 | primary ovarian follicle growth(GO:0001545) |
| 1.2 | 13.5 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 1.2 | 2.4 | GO:0046136 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
| 1.2 | 19.6 | GO:0043486 | histone exchange(GO:0043486) |
| 1.2 | 30.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 1.2 | 25.6 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 1.2 | 66.9 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 1.2 | 3.6 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 1.2 | 48.3 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 1.2 | 11.9 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 1.2 | 5.9 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 1.2 | 2.3 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 1.2 | 23.2 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 1.2 | 3.5 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 1.2 | 70.4 | GO:0031529 | ruffle organization(GO:0031529) |
| 1.1 | 18.3 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 1.1 | 4.6 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 1.1 | 4.6 | GO:0045074 | interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) |
| 1.1 | 90.3 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 1.1 | 5.7 | GO:2000542 | negative regulation of gastrulation(GO:2000542) |
| 1.1 | 3.4 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 1.1 | 6.8 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 1.1 | 7.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 1.1 | 2.2 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 1.1 | 23.5 | GO:0060148 | positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637) |
| 1.1 | 41.4 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 1.1 | 2.2 | GO:0010044 | response to aluminum ion(GO:0010044) |
| 1.1 | 8.9 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 1.1 | 4.4 | GO:0060849 | radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 1.1 | 3.3 | GO:1900220 | negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 1.1 | 12.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 1.1 | 11.0 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 1.1 | 15.4 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 1.1 | 34.9 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 1.1 | 13.1 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 1.1 | 6.5 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 1.1 | 5.3 | GO:0015692 | lead ion transport(GO:0015692) |
| 1.1 | 2.1 | GO:0002248 | connective tissue replacement involved in inflammatory response wound healing(GO:0002248) |
| 1.1 | 3.2 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 1.1 | 24.2 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 1.0 | 4.2 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 1.0 | 8.4 | GO:0010835 | regulation of protein ADP-ribosylation(GO:0010835) |
| 1.0 | 10.3 | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) |
| 1.0 | 3.1 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 1.0 | 3.1 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 1.0 | 30.6 | GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947) |
| 1.0 | 24.4 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
| 1.0 | 35.5 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 1.0 | 8.1 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 1.0 | 4.0 | GO:0009148 | pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) |
| 1.0 | 6.0 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 1.0 | 6.0 | GO:0052204 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) modification by host of symbiont molecular function(GO:0052428) |
| 1.0 | 4.0 | GO:0035750 | protein localization to myelin sheath abaxonal region(GO:0035750) |
| 1.0 | 1.0 | GO:1990791 | dorsal root ganglion development(GO:1990791) |
| 1.0 | 7.9 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 1.0 | 2.9 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 1.0 | 3.9 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 1.0 | 7.8 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 1.0 | 10.5 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.9 | 0.9 | GO:0001507 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
| 0.9 | 0.9 | GO:2000812 | regulation of barbed-end actin filament capping(GO:2000812) |
| 0.9 | 76.6 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.9 | 1.8 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
| 0.9 | 3.7 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.9 | 11.9 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.9 | 4.5 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
| 0.9 | 10.0 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.9 | 3.6 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.9 | 1.8 | GO:0010041 | response to iron(III) ion(GO:0010041) |
| 0.9 | 3.6 | GO:0070221 | sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) |
| 0.9 | 11.6 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.9 | 16.0 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.9 | 3.6 | GO:0035459 | cargo loading into vesicle(GO:0035459) |
| 0.9 | 5.3 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
| 0.9 | 6.0 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.9 | 4.3 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.9 | 16.3 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.9 | 6.8 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.9 | 17.1 | GO:0008228 | opsonization(GO:0008228) |
| 0.9 | 2.6 | GO:0030047 | actin modification(GO:0030047) |
| 0.8 | 3.4 | GO:0061052 | negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) |
| 0.8 | 21.2 | GO:0031440 | regulation of mRNA 3'-end processing(GO:0031440) |
| 0.8 | 5.9 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.8 | 4.2 | GO:0046070 | dGTP metabolic process(GO:0046070) |
| 0.8 | 7.5 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.8 | 3.3 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.8 | 1.7 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 0.8 | 8.1 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.8 | 11.3 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.8 | 11.3 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.8 | 4.0 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.8 | 10.3 | GO:0030953 | astral microtubule organization(GO:0030953) |
| 0.8 | 4.7 | GO:1901660 | calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034) |
| 0.8 | 3.9 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.8 | 3.1 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) |
| 0.8 | 13.7 | GO:0031639 | plasminogen activation(GO:0031639) |
| 0.8 | 12.2 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.8 | 3.0 | GO:0034670 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.8 | 4.5 | GO:0002483 | antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.8 | 2.3 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.7 | 15.0 | GO:0048311 | mitochondrion distribution(GO:0048311) |
| 0.7 | 3.0 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 0.7 | 11.9 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.7 | 5.9 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.7 | 9.5 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.7 | 10.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.7 | 3.6 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 0.7 | 3.6 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.7 | 18.0 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
| 0.7 | 6.4 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.7 | 2.8 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 0.7 | 13.9 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.7 | 2.1 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.7 | 6.2 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.7 | 6.9 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.7 | 21.3 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.7 | 45.9 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.7 | 2.1 | GO:1902218 | regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) |
| 0.7 | 15.7 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.7 | 3.4 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.7 | 2.7 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.7 | 5.3 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.7 | 6.0 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.7 | 34.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.7 | 4.0 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.7 | 2.6 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.7 | 18.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.7 | 6.5 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.7 | 12.4 | GO:0009226 | nucleotide-sugar biosynthetic process(GO:0009226) |
| 0.7 | 5.9 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.7 | 20.2 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.6 | 5.8 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.6 | 2.6 | GO:1904338 | regulation of dopaminergic neuron differentiation(GO:1904338) |
| 0.6 | 7.7 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.6 | 5.7 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.6 | 5.7 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.6 | 1.9 | GO:0031550 | positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550) |
| 0.6 | 1.3 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.6 | 1.3 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 0.6 | 1.9 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 0.6 | 1.2 | GO:0002436 | immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) |
| 0.6 | 2.5 | GO:1903069 | regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.6 | 6.2 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
| 0.6 | 22.6 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.6 | 6.7 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.6 | 7.9 | GO:0046040 | IMP metabolic process(GO:0046040) |
| 0.6 | 14.9 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.6 | 3.0 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.6 | 1.2 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.6 | 4.1 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.6 | 3.5 | GO:0002353 | kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) |
| 0.6 | 2.9 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.6 | 27.1 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.6 | 6.8 | GO:0021842 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 0.6 | 6.7 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.5 | 2.2 | GO:0043375 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 0.5 | 3.2 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.5 | 2.7 | GO:0043126 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.5 | 13.5 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.5 | 2.7 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.5 | 4.3 | GO:0060546 | negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547) |
| 0.5 | 6.9 | GO:0033015 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.5 | 2.7 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.5 | 1.1 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 0.5 | 7.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.5 | 2.1 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.5 | 2.5 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 0.5 | 4.6 | GO:0036109 | alpha-linolenic acid metabolic process(GO:0036109) |
| 0.5 | 7.0 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.5 | 3.0 | GO:0001712 | ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712) |
| 0.5 | 0.5 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.5 | 1.5 | GO:0060578 | subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) |
| 0.5 | 3.9 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.5 | 7.3 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.5 | 2.4 | GO:0032071 | regulation of endodeoxyribonuclease activity(GO:0032071) |
| 0.5 | 3.9 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.5 | 9.1 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.5 | 3.4 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.5 | 6.2 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.5 | 7.6 | GO:0042448 | progesterone metabolic process(GO:0042448) |
| 0.5 | 1.9 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.5 | 2.4 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.5 | 5.6 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.5 | 17.2 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.5 | 12.0 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.4 | 4.5 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.4 | 1.3 | GO:0002304 | gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305) |
| 0.4 | 2.7 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.4 | 3.5 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.4 | 1.7 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.4 | 4.3 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.4 | 30.1 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.4 | 3.0 | GO:1905123 | regulation of glucosylceramidase activity(GO:1905123) |
| 0.4 | 0.8 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
| 0.4 | 11.4 | GO:1901998 | toxin transport(GO:1901998) |
| 0.4 | 10.4 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.4 | 2.5 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.4 | 2.0 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.4 | 2.0 | GO:0030242 | pexophagy(GO:0030242) |
| 0.4 | 2.9 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.4 | 2.4 | GO:1904261 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.4 | 1.2 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.4 | 4.0 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.4 | 11.4 | GO:0051972 | regulation of telomerase activity(GO:0051972) |
| 0.4 | 4.7 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.4 | 10.5 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.4 | 10.0 | GO:0019430 | removal of superoxide radicals(GO:0019430) |
| 0.4 | 3.5 | GO:0015886 | heme transport(GO:0015886) |
| 0.4 | 2.3 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.4 | 1.9 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.4 | 6.8 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.4 | 2.7 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
| 0.4 | 1.1 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729) |
| 0.4 | 3.0 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.4 | 5.5 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.4 | 7.3 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.4 | 6.6 | GO:0097502 | mannosylation(GO:0097502) |
| 0.4 | 2.1 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.4 | 2.9 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.4 | 2.1 | GO:0097052 | L-kynurenine metabolic process(GO:0097052) |
| 0.4 | 3.9 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.3 | 4.2 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.3 | 1.0 | GO:0046532 | regulation of photoreceptor cell differentiation(GO:0046532) |
| 0.3 | 1.4 | GO:0098957 | anterograde axonal transport of mitochondrion(GO:0098957) |
| 0.3 | 1.7 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.3 | 3.7 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.3 | 1.0 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.3 | 7.0 | GO:0046039 | GTP metabolic process(GO:0046039) |
| 0.3 | 3.3 | GO:0015825 | L-serine transport(GO:0015825) |
| 0.3 | 5.2 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.3 | 7.7 | GO:0016573 | histone acetylation(GO:0016573) |
| 0.3 | 2.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.3 | 14.5 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.3 | 2.2 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.3 | 11.9 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.3 | 7.8 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.3 | 4.4 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.3 | 0.9 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.3 | 9.3 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.3 | 1.5 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.3 | 0.6 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.3 | 0.6 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.3 | 11.5 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.3 | 2.1 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.3 | 0.8 | GO:1902805 | positive regulation of synaptic vesicle priming(GO:0010808) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle exocytosis(GO:2000302) |
| 0.3 | 4.8 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.3 | 19.1 | GO:0045333 | cellular respiration(GO:0045333) |
| 0.3 | 1.3 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.3 | 1.8 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.3 | 2.9 | GO:0021730 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.3 | 3.1 | GO:0018126 | protein hydroxylation(GO:0018126) |
| 0.3 | 69.2 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.3 | 5.6 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.3 | 10.8 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.2 | 2.5 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.2 | 1.7 | GO:1990564 | protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.2 | 1.5 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.2 | 1.2 | GO:0071502 | cellular response to temperature stimulus(GO:0071502) |
| 0.2 | 16.2 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.2 | 8.2 | GO:0045815 | positive regulation of gene expression, epigenetic(GO:0045815) |
| 0.2 | 10.3 | GO:0018196 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.2 | 4.0 | GO:0051569 | regulation of histone H3-K4 methylation(GO:0051569) |
| 0.2 | 5.6 | GO:0034383 | low-density lipoprotein particle clearance(GO:0034383) |
| 0.2 | 0.7 | GO:0060215 | primitive hemopoiesis(GO:0060215) |
| 0.2 | 1.3 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.2 | 1.3 | GO:0017182 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202) |
| 0.2 | 6.5 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.2 | 19.9 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.2 | 3.7 | GO:0033866 | coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033) |
| 0.2 | 0.8 | GO:0050713 | negative regulation of interleukin-1 beta secretion(GO:0050713) |
| 0.2 | 4.8 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.2 | 0.8 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.2 | 0.4 | GO:0042494 | detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) |
| 0.2 | 2.5 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.2 | 0.6 | GO:0002503 | peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.2 | 2.4 | GO:0015919 | peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046) |
| 0.2 | 8.2 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.2 | 0.9 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.2 | 0.4 | GO:0040030 | regulation of molecular function, epigenetic(GO:0040030) |
| 0.2 | 0.3 | GO:0032912 | negative regulation of transforming growth factor beta2 production(GO:0032912) |
| 0.2 | 3.3 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.2 | 1.9 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.2 | 0.7 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.2 | 0.6 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.1 | 2.5 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.1 | 13.1 | GO:0006413 | translational initiation(GO:0006413) |
| 0.1 | 2.5 | GO:0071404 | cellular response to low-density lipoprotein particle stimulus(GO:0071404) |
| 0.1 | 0.7 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.1 | 1.9 | GO:1901661 | quinone metabolic process(GO:1901661) |
| 0.1 | 1.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 2.0 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.1 | 0.9 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 5.0 | GO:0003382 | epithelial cell morphogenesis(GO:0003382) |
| 0.1 | 1.8 | GO:0033146 | regulation of intracellular estrogen receptor signaling pathway(GO:0033146) |
| 0.1 | 2.4 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.1 | 6.7 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.1 | 1.7 | GO:0001967 | suckling behavior(GO:0001967) |
| 0.1 | 3.0 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.1 | 4.1 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.1 | 2.6 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.1 | 0.6 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 0.6 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 1.3 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.1 | 1.0 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.1 | 1.8 | GO:0060334 | regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 1.6 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 2.4 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.1 | 0.7 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 0.7 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.1 | 1.5 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.1 | 0.2 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.1 | 0.1 | GO:1990637 | response to prolactin(GO:1990637) |
| 0.1 | 1.2 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.0 | 0.3 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.0 | 0.2 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.0 | 0.3 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.0 | 0.5 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.0 | 0.3 | GO:0048714 | positive regulation of oligodendrocyte differentiation(GO:0048714) |
| 0.0 | 0.1 | GO:1904100 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.0 | 0.2 | GO:0046618 | drug export(GO:0046618) |
| 0.0 | 0.4 | GO:0060285 | cilium-dependent cell motility(GO:0060285) |
| 0.0 | 0.7 | GO:0008207 | C21-steroid hormone metabolic process(GO:0008207) |
| 0.0 | 0.6 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 0.0 | 0.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.2 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.0 | 1.6 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 0.2 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.0 | 0.1 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.0 | 0.4 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 1.1 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.2 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.0 | 0.5 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 0.0 | GO:1902617 | response to fluoride(GO:1902617) |
| 0.0 | 6.8 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.0 | 0.3 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.0 | 1.0 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
| 0.0 | 0.0 | GO:0071877 | regulation of adrenergic receptor signaling pathway(GO:0071877) |
| 0.0 | 0.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.0 | GO:0000960 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 0.0 | 0.1 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 0.3 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 1.1 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 0.1 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.7 | 58.6 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 11.5 | 34.5 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 10.4 | 31.1 | GO:1990913 | sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917) |
| 9.2 | 36.7 | GO:1990423 | RZZ complex(GO:1990423) |
| 8.3 | 33.4 | GO:0000811 | GINS complex(GO:0000811) |
| 8.2 | 49.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 7.2 | 28.7 | GO:0005715 | late recombination nodule(GO:0005715) |
| 6.7 | 20.2 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 6.6 | 33.2 | GO:0033503 | HULC complex(GO:0033503) |
| 6.5 | 64.6 | GO:0097255 | R2TP complex(GO:0097255) |
| 6.3 | 81.3 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 6.0 | 36.0 | GO:0001940 | male pronucleus(GO:0001940) |
| 5.5 | 22.1 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 5.5 | 65.5 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 5.4 | 26.8 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 5.3 | 26.7 | GO:0032044 | DSIF complex(GO:0032044) |
| 5.3 | 10.5 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 5.2 | 15.6 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 5.1 | 81.0 | GO:0034709 | methylosome(GO:0034709) |
| 5.0 | 65.3 | GO:0005688 | U6 snRNP(GO:0005688) |
| 4.9 | 14.8 | GO:0033597 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 4.8 | 43.6 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 4.7 | 14.1 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 4.6 | 13.8 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 4.6 | 13.7 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 4.5 | 31.4 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 4.1 | 12.3 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 4.1 | 12.3 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 4.1 | 32.6 | GO:0000796 | condensin complex(GO:0000796) |
| 4.0 | 12.0 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 4.0 | 11.9 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 3.9 | 19.4 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 3.8 | 57.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 3.8 | 26.8 | GO:0032021 | NELF complex(GO:0032021) |
| 3.8 | 22.8 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 3.7 | 33.7 | GO:0042382 | paraspeckles(GO:0042382) |
| 3.7 | 66.7 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 3.6 | 10.9 | GO:0097441 | basilar dendrite(GO:0097441) |
| 3.4 | 10.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 3.4 | 44.5 | GO:0042555 | MCM complex(GO:0042555) |
| 3.4 | 13.6 | GO:0071986 | Ragulator complex(GO:0071986) |
| 3.4 | 6.8 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 3.4 | 43.7 | GO:0030677 | ribonuclease P complex(GO:0030677) |
| 3.2 | 51.9 | GO:0097470 | ribbon synapse(GO:0097470) |
| 3.1 | 6.3 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
| 3.1 | 12.4 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 3.1 | 33.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 3.1 | 15.3 | GO:0097422 | tubular endosome(GO:0097422) |
| 3.0 | 9.1 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 3.0 | 15.0 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 3.0 | 26.8 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 2.9 | 11.8 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 2.9 | 5.8 | GO:0071817 | MMXD complex(GO:0071817) |
| 2.9 | 79.9 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 2.9 | 148.3 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 2.8 | 19.6 | GO:0031415 | NatA complex(GO:0031415) |
| 2.8 | 27.9 | GO:0044754 | autolysosome(GO:0044754) |
| 2.8 | 44.6 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 2.8 | 16.5 | GO:0000243 | commitment complex(GO:0000243) |
| 2.7 | 24.5 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 2.7 | 16.1 | GO:0061617 | MICOS complex(GO:0061617) |
| 2.6 | 10.5 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 2.5 | 7.6 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 2.5 | 12.5 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 2.5 | 37.0 | GO:0000812 | Swr1 complex(GO:0000812) |
| 2.5 | 19.7 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 2.4 | 167.8 | GO:0005876 | spindle microtubule(GO:0005876) |
| 2.4 | 9.7 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 2.4 | 12.1 | GO:0005749 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 2.4 | 16.8 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 2.4 | 14.2 | GO:0070545 | PeBoW complex(GO:0070545) |
| 2.4 | 63.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 2.3 | 20.5 | GO:1990630 | IRE1-RACK1-PP2A complex(GO:1990630) |
| 2.2 | 60.1 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 2.2 | 6.6 | GO:0033167 | ARC complex(GO:0033167) |
| 2.2 | 6.6 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 2.2 | 13.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 2.2 | 6.6 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 2.2 | 19.6 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 2.2 | 17.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 2.2 | 15.1 | GO:0072589 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 2.1 | 6.4 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 2.1 | 41.3 | GO:1902562 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 2.1 | 28.8 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 2.0 | 32.6 | GO:0005642 | annulate lamellae(GO:0005642) |
| 2.0 | 28.4 | GO:0022624 | proteasome accessory complex(GO:0022624) |
| 1.9 | 5.7 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 1.9 | 7.4 | GO:0000798 | nuclear cohesin complex(GO:0000798) |
| 1.9 | 27.8 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 1.8 | 5.5 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 1.8 | 25.8 | GO:0005869 | dynactin complex(GO:0005869) |
| 1.8 | 21.9 | GO:0090543 | Flemming body(GO:0090543) |
| 1.8 | 12.7 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 1.8 | 19.6 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 1.7 | 6.8 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 1.7 | 20.5 | GO:0001741 | XY body(GO:0001741) |
| 1.7 | 22.1 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 1.7 | 6.7 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 1.7 | 65.5 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 1.7 | 13.2 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 1.6 | 116.6 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 1.6 | 27.0 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 1.5 | 160.7 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 1.5 | 30.6 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 1.5 | 4.5 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 1.5 | 5.9 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 1.5 | 7.3 | GO:0070470 | plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470) |
| 1.4 | 25.8 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 1.4 | 15.7 | GO:0032039 | integrator complex(GO:0032039) |
| 1.4 | 21.0 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 1.4 | 23.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 1.4 | 99.3 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 1.4 | 70.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 1.3 | 2.7 | GO:0000805 | X chromosome(GO:0000805) |
| 1.3 | 5.3 | GO:0044307 | dendritic branch(GO:0044307) |
| 1.3 | 7.8 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 1.3 | 16.7 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 1.3 | 6.4 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 1.3 | 24.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 1.3 | 8.9 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 1.2 | 11.0 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 1.2 | 6.0 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 1.2 | 71.0 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 1.2 | 9.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 1.2 | 25.1 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 1.2 | 66.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 1.2 | 11.7 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 1.1 | 25.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 1.1 | 5.7 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 1.1 | 5.7 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 1.1 | 25.1 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 1.1 | 11.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 1.1 | 17.8 | GO:0033179 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 1.1 | 5.6 | GO:0070847 | core mediator complex(GO:0070847) |
| 1.1 | 10.0 | GO:0010369 | chromocenter(GO:0010369) |
| 1.1 | 19.9 | GO:0032433 | filopodium tip(GO:0032433) |
| 1.1 | 11.0 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 1.1 | 17.6 | GO:0031932 | TORC2 complex(GO:0031932) |
| 1.1 | 9.9 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 1.1 | 91.7 | GO:0035580 | specific granule lumen(GO:0035580) |
| 1.1 | 30.1 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 1.1 | 5.3 | GO:0070826 | paraferritin complex(GO:0070826) |
| 1.1 | 7.5 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 1.0 | 2.1 | GO:0038201 | TORC1 complex(GO:0031931) TOR complex(GO:0038201) |
| 1.0 | 10.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 1.0 | 5.2 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 1.0 | 7.1 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 1.0 | 5.0 | GO:0031523 | Myb complex(GO:0031523) |
| 1.0 | 19.1 | GO:0005652 | nuclear lamina(GO:0005652) |
| 1.0 | 2.0 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 1.0 | 6.9 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 1.0 | 6.9 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 1.0 | 13.8 | GO:0098687 | chromosomal region(GO:0098687) |
| 1.0 | 7.9 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 1.0 | 17.5 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 1.0 | 11.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.9 | 29.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.9 | 3.6 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.9 | 2.7 | GO:0098576 | lumenal side of membrane(GO:0098576) |
| 0.9 | 6.2 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.9 | 2.7 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.9 | 3.5 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.9 | 12.0 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.9 | 9.4 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.9 | 177.9 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.8 | 8.5 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.8 | 18.6 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.8 | 14.3 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.8 | 7.6 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.8 | 14.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.8 | 10.8 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.8 | 27.7 | GO:0030684 | preribosome(GO:0030684) |
| 0.8 | 8.1 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.8 | 11.9 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.8 | 7.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.8 | 8.7 | GO:0060171 | stereocilium membrane(GO:0060171) |
| 0.8 | 10.3 | GO:0043219 | lateral loop(GO:0043219) |
| 0.8 | 61.5 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.8 | 10.0 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.8 | 23.1 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.7 | 20.2 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.7 | 102.4 | GO:0042581 | specific granule(GO:0042581) |
| 0.7 | 2.2 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.7 | 0.7 | GO:0070522 | ERCC4-ERCC1 complex(GO:0070522) |
| 0.7 | 7.2 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.7 | 2.9 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.7 | 4.3 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.7 | 34.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.7 | 3.6 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.7 | 39.2 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.7 | 70.5 | GO:0000922 | spindle pole(GO:0000922) |
| 0.7 | 5.6 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.7 | 1.4 | GO:0043259 | laminin-10 complex(GO:0043259) |
| 0.7 | 3.4 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.7 | 48.7 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.7 | 3.4 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.7 | 8.7 | GO:0036452 | ESCRT complex(GO:0036452) |
| 0.7 | 5.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.7 | 6.0 | GO:0070449 | elongin complex(GO:0070449) |
| 0.6 | 20.4 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.6 | 10.8 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.6 | 74.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.6 | 18.2 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 0.6 | 25.0 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.6 | 1.9 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.6 | 3.7 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 0.6 | 32.9 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.6 | 84.9 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.6 | 25.3 | GO:0043034 | costamere(GO:0043034) |
| 0.6 | 3.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.6 | 4.0 | GO:0030891 | VCB complex(GO:0030891) |
| 0.6 | 4.0 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.6 | 62.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.6 | 9.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.5 | 9.9 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.5 | 9.1 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.5 | 4.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.5 | 19.1 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.5 | 25.9 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.5 | 2.4 | GO:0045180 | basal cortex(GO:0045180) |
| 0.5 | 2.8 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.5 | 12.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.4 | 2.2 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.4 | 1.3 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.4 | 56.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.4 | 4.3 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.4 | 18.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.4 | 302.2 | GO:0005730 | nucleolus(GO:0005730) |
| 0.4 | 6.5 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.4 | 3.3 | GO:0034464 | BBSome(GO:0034464) |
| 0.4 | 0.8 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
| 0.4 | 3.5 | GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178) |
| 0.4 | 9.5 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.4 | 2.5 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.4 | 13.4 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.3 | 2.4 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.3 | 41.3 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.3 | 11.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.3 | 1.3 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.3 | 7.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.3 | 2.0 | GO:0043073 | germ cell nucleus(GO:0043073) |
| 0.3 | 4.2 | GO:0015030 | Cajal body(GO:0015030) |
| 0.3 | 2.8 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.3 | 3.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 85.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.2 | 5.7 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.2 | 10.4 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.2 | 44.1 | GO:0019866 | organelle inner membrane(GO:0019866) |
| 0.2 | 0.8 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
| 0.2 | 8.3 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.2 | 3.3 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.2 | 0.8 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.2 | 2.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.2 | 11.3 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.2 | 1.5 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.2 | 0.8 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.2 | 3.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.2 | 4.0 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.1 | 1.1 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.1 | 8.5 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.1 | 0.8 | GO:0000791 | euchromatin(GO:0000791) |
| 0.1 | 0.4 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 0.1 | 1.5 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 5.1 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.1 | 2.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 2.0 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.1 | 21.6 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.1 | 2.3 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 1.9 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.1 | 25.5 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 1.0 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 0.4 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.1 | 0.2 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 0.1 | 0.5 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.1 | 3.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 0.4 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 0.7 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 0.6 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 2.5 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.6 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 3.2 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 22.0 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 0.8 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 15.3 | 106.8 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 11.0 | 44.2 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 11.0 | 33.1 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 11.0 | 32.9 | GO:0070538 | oleic acid binding(GO:0070538) |
| 10.9 | 32.8 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 10.7 | 43.0 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 10.4 | 31.1 | GO:0002135 | CTP binding(GO:0002135) |
| 9.8 | 29.3 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 9.2 | 55.3 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 8.8 | 43.8 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 8.5 | 51.2 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 8.1 | 24.2 | GO:0033989 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594) |
| 7.9 | 55.2 | GO:0030613 | oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) |
| 7.3 | 43.6 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 7.0 | 49.2 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 6.7 | 26.9 | GO:0047676 | arachidonate-CoA ligase activity(GO:0047676) |
| 6.6 | 33.1 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 6.5 | 25.9 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 6.4 | 19.3 | GO:0008670 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) |
| 6.3 | 44.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 6.2 | 18.7 | GO:0031208 | POZ domain binding(GO:0031208) |
| 6.0 | 23.8 | GO:0004488 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 5.9 | 11.9 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 5.9 | 23.7 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 5.7 | 17.1 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 5.6 | 5.6 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 5.5 | 16.4 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 5.4 | 43.2 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 5.4 | 21.5 | GO:0102007 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 5.1 | 25.7 | GO:0047280 | nicotinamide phosphoribosyltransferase activity(GO:0047280) |
| 5.0 | 15.0 | GO:0034512 | box C/D snoRNA binding(GO:0034512) |
| 4.9 | 14.7 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 4.8 | 77.2 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
| 4.8 | 9.6 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 4.8 | 38.3 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 4.7 | 4.7 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 4.6 | 18.4 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 4.6 | 73.1 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 4.5 | 26.8 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 4.5 | 17.9 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 4.4 | 17.6 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 4.4 | 30.5 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 4.3 | 17.1 | GO:0043515 | kinetochore binding(GO:0043515) |
| 4.2 | 12.6 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 4.2 | 12.5 | GO:0070336 | flap-structured DNA binding(GO:0070336) |
| 4.2 | 4.2 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 4.1 | 12.3 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 4.0 | 16.1 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
| 4.0 | 27.7 | GO:0005346 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217) |
| 3.9 | 43.2 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 3.9 | 35.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 3.8 | 57.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 3.8 | 22.6 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 3.7 | 11.1 | GO:0043035 | chromatin insulator sequence binding(GO:0043035) |
| 3.6 | 14.5 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 3.6 | 25.3 | GO:0004459 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 3.6 | 10.7 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 3.6 | 17.8 | GO:1990254 | keratin filament binding(GO:1990254) |
| 3.5 | 10.6 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 3.5 | 24.2 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 3.4 | 6.9 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 3.4 | 27.4 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 3.4 | 27.4 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 3.3 | 10.0 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 3.3 | 13.3 | GO:0003983 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 3.3 | 9.9 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 3.3 | 16.3 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 3.2 | 90.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 3.2 | 129.0 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 3.2 | 38.5 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 3.2 | 6.4 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 3.2 | 22.2 | GO:0043996 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 3.2 | 9.5 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 3.1 | 147.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 3.1 | 9.3 | GO:0000035 | acyl binding(GO:0000035) |
| 3.1 | 15.5 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 3.1 | 15.4 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 3.0 | 84.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 3.0 | 12.1 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 3.0 | 26.8 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 3.0 | 8.9 | GO:0055100 | adiponectin binding(GO:0055100) |
| 2.9 | 28.9 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 2.8 | 28.4 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 2.8 | 50.9 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 2.8 | 22.5 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 2.8 | 11.1 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 2.8 | 24.8 | GO:0018812 | 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) |
| 2.7 | 13.7 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 2.7 | 19.1 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 2.7 | 10.8 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 2.6 | 13.2 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 2.6 | 7.9 | GO:0050146 | nucleoside phosphotransferase activity(GO:0050146) |
| 2.6 | 18.2 | GO:0004470 | malic enzyme activity(GO:0004470) |
| 2.6 | 28.5 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 2.6 | 7.7 | GO:0046577 | long-chain-alcohol oxidase activity(GO:0046577) |
| 2.5 | 32.9 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 2.5 | 15.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 2.5 | 7.6 | GO:0045550 | geranylgeranyl reductase activity(GO:0045550) |
| 2.5 | 9.9 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 2.4 | 22.0 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 2.4 | 45.8 | GO:0031404 | chloride ion binding(GO:0031404) |
| 2.4 | 7.2 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 2.4 | 33.4 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 2.4 | 7.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 2.3 | 84.1 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 2.3 | 7.0 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 2.3 | 13.8 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 2.3 | 6.8 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 2.3 | 20.3 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 2.2 | 2.2 | GO:0070404 | NADH binding(GO:0070404) |
| 2.2 | 17.8 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 2.2 | 8.7 | GO:0004598 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 2.2 | 30.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 2.2 | 63.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 2.2 | 6.5 | GO:0031403 | lithium ion binding(GO:0031403) |
| 2.2 | 6.5 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 2.2 | 15.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 2.1 | 17.1 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 2.1 | 64.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 2.0 | 22.3 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 2.0 | 38.6 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 2.0 | 8.1 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 2.0 | 16.0 | GO:0042731 | PH domain binding(GO:0042731) |
| 2.0 | 6.0 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 2.0 | 4.0 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 2.0 | 7.9 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 1.9 | 15.4 | GO:0019863 | IgE binding(GO:0019863) |
| 1.9 | 21.1 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 1.9 | 14.9 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 1.8 | 5.5 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 1.8 | 16.3 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 1.8 | 1.8 | GO:0016679 | oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) |
| 1.8 | 7.2 | GO:0033897 | ribonuclease T2 activity(GO:0033897) |
| 1.8 | 7.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 1.7 | 5.2 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 1.7 | 62.0 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 1.7 | 51.5 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 1.6 | 66.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 1.6 | 25.8 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 1.6 | 20.7 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 1.6 | 9.5 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 1.6 | 11.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 1.6 | 33.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 1.6 | 17.1 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 1.5 | 6.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 1.5 | 9.1 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 1.5 | 34.9 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 1.5 | 6.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 1.5 | 4.6 | GO:0000248 | C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704) |
| 1.5 | 7.5 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 1.5 | 16.6 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) |
| 1.5 | 17.9 | GO:0050700 | CARD domain binding(GO:0050700) |
| 1.5 | 5.9 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 1.5 | 10.2 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 1.5 | 5.8 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 1.4 | 4.3 | GO:0033265 | choline binding(GO:0033265) |
| 1.4 | 8.6 | GO:0004310 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 1.4 | 19.6 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 1.4 | 4.2 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 1.4 | 30.5 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 1.4 | 5.5 | GO:0051733 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 1.4 | 177.2 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 1.3 | 12.1 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 1.3 | 33.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 1.3 | 23.9 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 1.3 | 6.6 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 1.3 | 69.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 1.3 | 3.9 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 1.3 | 11.7 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 1.3 | 5.2 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 1.3 | 5.2 | GO:0004146 | dihydrofolate reductase activity(GO:0004146) |
| 1.3 | 21.9 | GO:0017069 | snRNA binding(GO:0017069) |
| 1.3 | 10.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 1.3 | 6.4 | GO:0004376 | glycolipid mannosyltransferase activity(GO:0004376) |
| 1.3 | 3.8 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 1.3 | 21.4 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 1.3 | 267.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.3 | 22.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 1.3 | 32.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 1.2 | 7.5 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 1.2 | 3.7 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 1.2 | 2.5 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 1.2 | 4.9 | GO:0047685 | amine sulfotransferase activity(GO:0047685) |
| 1.2 | 8.6 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 1.2 | 9.8 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 1.2 | 36.1 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 1.2 | 9.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 1.2 | 19.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 1.2 | 9.5 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 1.2 | 49.7 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 1.2 | 10.4 | GO:0045545 | syndecan binding(GO:0045545) |
| 1.1 | 3.4 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 1.1 | 7.9 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 1.1 | 32.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 1.1 | 8.9 | GO:0050733 | RS domain binding(GO:0050733) |
| 1.1 | 12.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 1.1 | 3.3 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 1.1 | 4.4 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 1.1 | 10.9 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 1.1 | 15.2 | GO:0031386 | protein tag(GO:0031386) |
| 1.1 | 20.5 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 1.1 | 3.2 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 1.1 | 6.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 1.1 | 9.6 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 1.1 | 24.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 1.1 | 4.2 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 1.0 | 3.1 | GO:0004056 | argininosuccinate lyase activity(GO:0004056) |
| 1.0 | 10.2 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 1.0 | 22.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 1.0 | 3.0 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 1.0 | 10.1 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 1.0 | 15.1 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 1.0 | 4.0 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 1.0 | 2.0 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 1.0 | 12.0 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 1.0 | 25.9 | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 1.0 | 24.7 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 1.0 | 16.5 | GO:0000339 | RNA cap binding(GO:0000339) |
| 1.0 | 12.6 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 1.0 | 16.4 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 1.0 | 4.8 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 1.0 | 5.7 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.9 | 11.9 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.9 | 2.7 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.9 | 60.6 | GO:0019003 | GDP binding(GO:0019003) |
| 0.9 | 13.1 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.9 | 6.0 | GO:0015288 | porin activity(GO:0015288) |
| 0.9 | 5.2 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.8 | 8.5 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.8 | 4.2 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 0.8 | 3.3 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.8 | 14.9 | GO:0004659 | prenyltransferase activity(GO:0004659) |
| 0.8 | 2.5 | GO:0030548 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.8 | 10.7 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.8 | 2.5 | GO:0004963 | follicle-stimulating hormone receptor activity(GO:0004963) |
| 0.8 | 9.0 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.8 | 11.4 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
| 0.8 | 5.7 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.8 | 42.2 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.8 | 11.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.8 | 13.2 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.8 | 23.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.8 | 24.1 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.7 | 5.2 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.7 | 10.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.7 | 40.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.7 | 8.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.7 | 12.5 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.7 | 2.2 | GO:0004958 | prostaglandin F receptor activity(GO:0004958) |
| 0.7 | 10.2 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.7 | 35.4 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.7 | 33.6 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.7 | 5.0 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.7 | 2.1 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.7 | 4.2 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.7 | 3.5 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.7 | 3.5 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.7 | 15.8 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.7 | 5.5 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.7 | 31.5 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.7 | 3.4 | GO:0032405 | MutLalpha complex binding(GO:0032405) |
| 0.7 | 8.8 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.7 | 5.4 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.7 | 4.6 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.6 | 1.9 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 0.6 | 14.9 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.6 | 27.0 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.6 | 4.5 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.6 | 12.1 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.6 | 5.1 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.6 | 1.8 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.6 | 42.8 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.6 | 14.8 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.6 | 3.6 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.6 | 6.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.6 | 8.3 | GO:0050543 | icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
| 0.6 | 6.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.6 | 4.1 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.6 | 4.5 | GO:0070697 | activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699) |
| 0.6 | 2.3 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.6 | 6.2 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.6 | 5.0 | GO:0046790 | virion binding(GO:0046790) |
| 0.5 | 13.1 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.5 | 6.0 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.5 | 4.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.5 | 1.6 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.5 | 3.7 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.5 | 1.6 | GO:0052836 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 0.5 | 4.1 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.5 | 28.0 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 0.5 | 4.5 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.5 | 13.5 | GO:0001848 | complement binding(GO:0001848) |
| 0.5 | 1.9 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.5 | 2.4 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.5 | 12.7 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.5 | 31.1 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.4 | 1.8 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.4 | 1.3 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.4 | 3.5 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.4 | 19.2 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.4 | 3.4 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.4 | 22.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.4 | 13.3 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.4 | 4.1 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.4 | 14.8 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.4 | 6.0 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.4 | 3.6 | GO:0016886 | ligase activity, forming phosphoric ester bonds(GO:0016886) |
| 0.4 | 3.9 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.4 | 2.7 | GO:0016892 | endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
| 0.4 | 7.5 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.4 | 2.6 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.4 | 5.4 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.4 | 2.5 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.3 | 2.4 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.3 | 18.8 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.3 | 0.7 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.3 | 4.5 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.3 | 1.7 | GO:0004084 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.3 | 4.4 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.3 | 7.1 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.3 | 2.7 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.3 | 5.6 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.3 | 12.1 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.3 | 10.3 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.3 | 0.3 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.3 | 2.9 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.3 | 4.2 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.3 | 5.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.3 | 5.4 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.3 | 4.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.3 | 3.7 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.3 | 9.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.3 | 13.6 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.3 | 10.2 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.3 | 29.4 | GO:0004386 | helicase activity(GO:0004386) |
| 0.3 | 8.1 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.3 | 12.2 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.3 | 1.4 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.3 | 3.4 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.3 | 3.0 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.3 | 7.8 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.3 | 1.3 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.3 | 2.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.3 | 3.8 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.3 | 3.0 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.2 | 1.0 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.2 | 3.4 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.2 | 2.1 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.2 | 4.3 | GO:0043495 | protein anchor(GO:0043495) |
| 0.2 | 8.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.2 | 3.0 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.2 | 10.0 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.2 | 7.4 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.2 | 1.5 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.2 | 2.7 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.2 | 23.7 | GO:0042393 | histone binding(GO:0042393) |
| 0.2 | 262.6 | GO:0003723 | RNA binding(GO:0003723) |
| 0.2 | 2.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.2 | 0.4 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 0.2 | 1.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.2 | 6.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 5.2 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.2 | 0.5 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.2 | 3.1 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.2 | 0.9 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.2 | 6.5 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.1 | 3.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 1.0 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.1 | 3.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.4 | GO:0005011 | macrophage colony-stimulating factor receptor activity(GO:0005011) |
| 0.1 | 1.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 0.6 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 8.3 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.1 | 0.5 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 0.3 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 0.1 | 0.8 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 5.1 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 1.5 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 0.3 | GO:0052794 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 0.1 | 0.7 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 1.0 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.1 | 2.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.6 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.1 | 0.4 | GO:0031782 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 0.1 | 1.8 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) |
| 0.1 | 2.3 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
| 0.1 | 0.6 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 0.9 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.1 | 1.7 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.1 | 1.0 | GO:0010857 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857) |
| 0.1 | 1.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 1.3 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 0.8 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 0.5 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.1 | 0.5 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 0.8 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.0 | 0.5 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 4.0 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.2 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.0 | 0.4 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 1.3 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 3.0 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.0 | 0.3 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 0.2 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.0 | 0.3 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 1.8 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 2.0 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 0.4 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.1 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
| 0.0 | 0.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.2 | GO:0070840 | dynein complex binding(GO:0070840) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 63.4 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 2.6 | 135.0 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 2.1 | 128.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 2.1 | 2.1 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 2.0 | 5.9 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 1.8 | 56.1 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 1.8 | 35.5 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 1.7 | 75.9 | PID MYC PATHWAY | C-MYC pathway |
| 1.6 | 27.8 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 1.5 | 50.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 1.4 | 44.7 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 1.3 | 5.2 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 1.3 | 17.7 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 1.2 | 18.9 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 1.2 | 9.4 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 1.1 | 97.0 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 1.1 | 61.8 | PID PLK1 PATHWAY | PLK1 signaling events |
| 1.1 | 2.1 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 1.1 | 33.8 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 1.0 | 72.1 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 1.0 | 44.4 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 1.0 | 4.0 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.9 | 33.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.9 | 88.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.8 | 15.5 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.8 | 5.7 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.8 | 19.1 | PID ATM PATHWAY | ATM pathway |
| 0.8 | 11.6 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.7 | 5.9 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.7 | 60.8 | PID E2F PATHWAY | E2F transcription factor network |
| 0.7 | 61.9 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.7 | 21.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.7 | 41.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.7 | 16.3 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.6 | 12.7 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.6 | 4.0 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.5 | 88.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.5 | 18.4 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.5 | 48.5 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.5 | 16.8 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.5 | 33.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.4 | 17.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.4 | 30.6 | PID P73PATHWAY | p73 transcription factor network |
| 0.4 | 11.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.4 | 17.2 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.4 | 16.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.4 | 19.6 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.4 | 10.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.4 | 3.0 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.4 | 9.9 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.4 | 11.8 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.4 | 3.9 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.3 | 13.3 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.3 | 5.5 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.3 | 3.4 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.3 | 9.4 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.3 | 9.4 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.3 | 3.8 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.2 | 11.2 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.2 | 1.8 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.2 | 3.2 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.2 | 1.5 | PID EPO PATHWAY | EPO signaling pathway |
| 0.2 | 4.7 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.2 | 7.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.2 | 4.0 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.2 | 5.7 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 9.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 3.2 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 0.9 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 2.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 1.4 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 2.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 1.6 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 1.0 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.7 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 1.4 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.4 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.2 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.2 | 77.9 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 4.5 | 127.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 4.5 | 129.5 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 4.1 | 95.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 3.7 | 121.1 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 3.3 | 260.3 | REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX | Genes involved in CDT1 association with the CDC6:ORC:origin complex |
| 3.2 | 56.8 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 3.0 | 96.3 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 2.8 | 25.4 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 2.7 | 46.5 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 2.7 | 92.7 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 2.7 | 2.7 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 2.6 | 50.1 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 2.6 | 56.7 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 2.6 | 84.3 | REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
| 2.5 | 119.1 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 2.4 | 48.2 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 2.4 | 92.8 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 2.3 | 30.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 2.3 | 36.1 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 2.2 | 33.2 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 2.1 | 14.8 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 2.0 | 14.2 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 2.0 | 8.0 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 2.0 | 19.6 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 1.9 | 9.7 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 1.9 | 36.4 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 1.8 | 33.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 1.8 | 15.8 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 1.7 | 38.5 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 1.7 | 13.9 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 1.7 | 13.3 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 1.6 | 97.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 1.6 | 14.7 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 1.6 | 18.9 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 1.6 | 120.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 1.6 | 54.7 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 1.5 | 38.0 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.4 | 22.1 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 1.4 | 16.6 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 1.4 | 23.1 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 1.3 | 19.4 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 1.3 | 5.2 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 1.3 | 33.6 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 1.3 | 33.3 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 1.3 | 47.1 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 1.2 | 49.8 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 1.2 | 141.9 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
| 1.2 | 13.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 1.2 | 17.9 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 1.2 | 32.6 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 1.1 | 32.1 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 1.1 | 10.0 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 1.1 | 22.9 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 1.1 | 21.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 1.0 | 10.4 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 1.0 | 46.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 1.0 | 79.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 1.0 | 22.6 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 1.0 | 8.6 | REACTOME G2 M CHECKPOINTS | Genes involved in G2/M Checkpoints |
| 0.9 | 6.5 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.9 | 16.4 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.9 | 9.1 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.9 | 13.3 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.8 | 28.7 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.8 | 6.6 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.8 | 22.1 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.8 | 21.2 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.8 | 5.4 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.8 | 127.5 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.8 | 3.8 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.8 | 24.2 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.7 | 11.2 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.7 | 5.9 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.7 | 21.9 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.7 | 33.9 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.7 | 26.7 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.7 | 8.9 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.7 | 13.4 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.7 | 105.5 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.7 | 14.7 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.6 | 5.0 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.6 | 38.9 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.6 | 14.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.6 | 6.2 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.6 | 43.3 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.6 | 10.3 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.6 | 16.3 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.6 | 10.2 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.6 | 3.4 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.6 | 13.5 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.6 | 8.9 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.5 | 6.4 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.5 | 10.0 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.5 | 8.9 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.5 | 5.9 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.5 | 7.5 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.4 | 10.6 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.4 | 8.7 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.4 | 6.0 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.4 | 9.4 | REACTOME PURINE METABOLISM | Genes involved in Purine metabolism |
| 0.4 | 8.5 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.4 | 1.2 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.4 | 4.2 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.4 | 0.7 | REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
| 0.4 | 9.6 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.4 | 10.3 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.3 | 1.4 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.3 | 12.8 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.3 | 3.6 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 0.3 | 7.8 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.3 | 8.3 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.3 | 5.4 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.3 | 9.0 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.3 | 13.1 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.3 | 7.7 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 2.4 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.3 | 10.2 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.3 | 7.0 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.3 | 9.0 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.3 | 16.9 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.3 | 12.5 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.2 | 2.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 1.2 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 1.8 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.1 | 1.0 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 2.0 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 2.7 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 3.5 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 1.3 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 2.4 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.1 | 3.2 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 0.8 | REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
| 0.1 | 2.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 1.6 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.1 | 0.9 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 0.8 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 2.1 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 2.3 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 1.1 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.1 | 1.0 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 1.0 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 1.7 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 0.9 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 3.7 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.5 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.1 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.0 | 0.0 | REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK |