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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZNF652

Z-value: 5.53

Motif logo

Transcription factors associated with ZNF652

Gene Symbol Gene ID Gene Info
ENSG00000198740.9 ZNF652

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF652hg38_v1_chr17_-_49362206_49362279-0.364.1e-08Click!

Activity profile of ZNF652 motif

Sorted Z-values of ZNF652 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF652

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_111911759 30.63 ENST00000650687.2
crystallin alpha B
chr4_-_89836213 27.27 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chrX_+_103776831 27.14 ENST00000621218.5
ENST00000619236.1
proteolipid protein 1
chr11_+_45146631 22.60 ENST00000534751.3
ENST00000683152.1
PR/SET domain 11
chr4_-_164977644 17.72 ENST00000329314.6
ENST00000508856.2
tripartite motif containing 61
chr16_+_56589521 16.93 ENST00000200691.5
ENST00000570176.1
metallothionein 3
chr10_-_15371225 16.62 ENST00000378116.9
family with sequence similarity 171 member A1
chr21_-_26843063 15.73 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843012 15.33 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr6_-_6004040 14.40 ENST00000622188.4
neuritin 1
chr9_-_35111573 14.30 ENST00000378561.5
ENST00000603301.5
family with sequence similarity 214 member B
chr19_+_37507129 13.90 ENST00000586138.5
ENST00000588578.5
ENST00000587986.5
zinc finger protein 793
chr11_-_119423162 13.46 ENST00000284240.10
ENST00000524970.5
Thy-1 cell surface antigen
chr17_+_50095331 12.94 ENST00000503176.6
pyruvate dehydrogenase kinase 2
chr11_+_57598184 12.70 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr4_-_89835617 11.86 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr16_-_57284654 11.38 ENST00000613167.4
ENST00000219207.10
ENST00000569059.5
plasmolipin
chr11_-_35526024 11.37 ENST00000615849.4
peptidase domain containing associated with muscle regeneration 1
chr14_-_100568475 11.11 ENST00000553553.6
brain enriched guanylate kinase associated
chr9_-_35111423 11.06 ENST00000378557.1
family with sequence similarity 214 member B
chr8_-_109644766 10.69 ENST00000533065.5
ENST00000276646.14
syntabulin
chr19_+_53044730 10.68 ENST00000601417.3
endogenous retrovirus group V member 2, envelope
chr1_-_203351115 10.66 ENST00000354955.5
fibromodulin
chr11_-_35525603 10.43 ENST00000529303.1
ENST00000619888.5
ENST00000622144.4
peptidase domain containing associated with muscle regeneration 1
chr17_+_50095285 10.35 ENST00000503614.5
pyruvate dehydrogenase kinase 2
chr2_+_99181173 10.13 ENST00000338148.8
ENST00000409145.5
mitochondrial ribosomal protein L30
chr6_+_72216745 10.13 ENST00000517827.5
regulating synaptic membrane exocytosis 1
chr20_-_3173516 10.03 ENST00000360342.7
ENST00000645462.1
ENST00000337576.7
leucine zipper tumor suppressor family member 3
chr17_+_45148468 9.88 ENST00000332499.4
HEXIM P-TEFb complex subunit 1
chr1_+_152663378 9.56 ENST00000368784.2
late cornified envelope 2D
chr17_+_49788672 9.54 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
lysine acetyltransferase 7
chr3_+_159273235 9.52 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr2_-_2324323 9.47 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr14_+_92121953 9.30 ENST00000298875.9
ENST00000553427.5
cleavage and polyadenylation specific factor 2
chr17_-_81166160 9.28 ENST00000326724.9
apoptosis associated tyrosine kinase
chr12_+_8843236 9.17 ENST00000541459.5
alpha-2-macroglobulin like 1
chr8_+_1973668 9.04 ENST00000320248.4
kelch repeat and BTB domain containing 11
chr1_-_151909501 9.00 ENST00000368814.8
thioesterase superfamily member 4
chr5_-_11588842 8.95 ENST00000503622.5
catenin delta 2
chr19_+_37506931 8.90 ENST00000627814.3
ENST00000587143.5
zinc finger protein 793
chr19_+_41003946 8.87 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr6_+_39793008 8.87 ENST00000398904.6
dishevelled associated activator of morphogenesis 2
chr1_+_168179030 8.68 ENST00000367830.3
TOR signaling pathway regulator
chr15_-_65133780 8.58 ENST00000204549.9
programmed cell death 7
chr6_+_39792993 8.40 ENST00000538976.5
dishevelled associated activator of morphogenesis 2
chr19_+_40467145 8.28 ENST00000338932.7
spectrin beta, non-erythrocytic 4
chr1_+_156728916 8.20 ENST00000519086.5
ribosomal RNA adenine dimethylase domain containing 1
chr7_+_23246697 8.19 ENST00000381990.6
ENST00000409458.3
ENST00000647578.1
ENST00000258733.9
glycoprotein nmb
chr3_+_157436842 8.14 ENST00000295927.4
pentraxin 3
chr5_+_136059151 8.09 ENST00000503087.1
transforming growth factor beta induced
chr11_-_129024157 8.00 ENST00000392657.7
Rho GTPase activating protein 32
chr5_-_176630517 7.91 ENST00000393693.7
ENST00000614675.4
synuclein beta
chr1_-_161309961 7.70 ENST00000533357.5
ENST00000672602.2
ENST00000526189.3
myelin protein zero
chr13_-_37598750 7.63 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr4_-_98657635 7.63 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
tetraspanin 5
chr14_-_21537206 7.60 ENST00000614342.1
spalt like transcription factor 2
chr19_-_3868993 7.29 ENST00000674260.1
ENST00000592398.1
ENST00000439086.2
ENST00000262961.9
zinc finger RNA binding protein 2
chr14_+_85530127 7.26 ENST00000330753.6
fibronectin leucine rich transmembrane protein 2
chr5_+_126423363 7.17 ENST00000285689.8
GRAM domain containing 2B
chr1_-_156677400 7.12 ENST00000368223.4
nestin
chr5_+_126423176 7.10 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr5_+_126423122 7.02 ENST00000515200.5
GRAM domain containing 2B
chr5_+_141364231 6.97 ENST00000611914.1
protocadherin gamma subfamily A, 5
chr12_+_6873561 6.93 ENST00000433346.5
leucine rich repeat containing 23
chr9_+_112486819 6.81 ENST00000337530.11
KIAA1958
chr5_-_176630364 6.81 ENST00000310112.7
synuclein beta
chr2_-_217944005 6.78 ENST00000611415.4
ENST00000615025.5
ENST00000449814.1
ENST00000171887.8
tensin 1
chr2_-_189179754 6.64 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr3_-_127722562 6.59 ENST00000487473.5
ENST00000484451.1
monoglyceride lipase
chr10_-_59753444 6.59 ENST00000594536.5
ENST00000414264.6
myoregulin
chr11_-_86672114 6.58 ENST00000393324.7
malic enzyme 3
chr1_-_150808251 6.57 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr5_+_136058849 6.56 ENST00000508076.5
transforming growth factor beta induced
chr17_+_50532713 6.47 ENST00000503690.5
ENST00000514874.5
ENST00000268933.8
epsin 3
chr2_-_240820945 6.25 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
kinesin family member 1A
chr14_-_23302823 6.19 ENST00000452015.9
protein phosphatase 1 regulatory subunit 3E
chr20_-_17682060 6.04 ENST00000455029.3
ribosome binding protein 1
chr10_-_28282086 6.02 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr15_+_73684373 5.99 ENST00000558689.5
ENST00000560786.6
ENST00000318443.10
ENST00000561213.5
CD276 molecule
chr19_+_52274443 5.90 ENST00000600821.5
ENST00000595149.5
ENST00000595000.5
ENST00000593612.1
zinc finger protein 766
chr3_-_44477639 5.87 ENST00000396077.8
zinc finger protein 445
chr14_-_100568070 5.85 ENST00000557378.6
ENST00000443071.6
ENST00000637646.1
brain enriched guanylate kinase associated
chr14_-_21536928 5.85 ENST00000613414.4
spalt like transcription factor 2
chr8_-_23404076 5.83 ENST00000524168.1
ENST00000389131.8
ENST00000523833.2
ENST00000519243.1
lysyl oxidase like 2
chr16_+_31472130 5.79 ENST00000394863.8
ENST00000565360.5
ENST00000361773.7
transforming growth factor beta 1 induced transcript 1
chr6_+_72216442 5.77 ENST00000425662.6
ENST00000453976.6
regulating synaptic membrane exocytosis 1
chr16_+_67893244 5.76 ENST00000291041.6
ENST00000570631.5
protein serine kinase H1
chr19_+_41219177 5.76 ENST00000301178.9
AXL receptor tyrosine kinase
chr6_+_99521027 5.75 ENST00000452647.3
ENST00000636394.1
thiosulfate sulfurtransferase like domain containing 3
chr11_-_86672419 5.72 ENST00000524826.7
ENST00000532471.1
malic enzyme 3
chr5_-_112419251 5.64 ENST00000261486.6
erythrocyte membrane protein band 4.1 like 4A
chr4_-_76213520 5.58 ENST00000640634.1
scavenger receptor class B member 2
chr11_+_107591222 5.50 ENST00000443271.2
ELMO domain containing 1
chr18_+_35041387 5.47 ENST00000538170.6
ENST00000300249.10
ENST00000588910.5
microtubule associated protein RP/EB family member 2
chr3_-_9952337 5.45 ENST00000411976.2
ENST00000412055.6
proline rich transmembrane protein 3
chr4_-_76213724 5.39 ENST00000639738.1
scavenger receptor class B member 2
chr1_+_152675295 5.37 ENST00000368783.1
late cornified envelope 2C
chr8_+_93754844 5.30 ENST00000684064.1
ENST00000498673.5
ENST00000518319.5
transmembrane protein 67
chr15_+_75347610 5.22 ENST00000564784.5
ENST00000569035.5
nei like DNA glycosylase 1
chr16_+_6019016 5.21 ENST00000550418.6
RNA binding fox-1 homolog 1
chr17_-_42181081 5.13 ENST00000607371.5
potassium voltage-gated channel subfamily H member 4
chr17_-_39688016 5.11 ENST00000579146.5
ENST00000300658.9
ENST00000378011.8
ENST00000429199.6
post-GPI attachment to proteins phospholipase 3
chr8_-_27772585 5.09 ENST00000522915.5
ENST00000356537.9
coiled-coil domain containing 25
chr17_+_28473278 5.06 ENST00000444914.7
solute carrier family 13 member 2
chr2_-_187513641 5.05 ENST00000392365.5
ENST00000435414.5
tissue factor pathway inhibitor
chr19_+_52570268 4.98 ENST00000596514.5
ENST00000391785.8
ENST00000301093.6
zinc finger protein 701
chr17_+_68259164 4.92 ENST00000448504.6
arylsulfatase G
chr1_+_215573775 4.89 ENST00000448333.1
potassium channel tetramerization domain containing 3
chr3_-_42581936 4.88 ENST00000423701.6
ENST00000420163.1
ENST00000416880.5
ENST00000264454.8
ENST00000273156.11
SEC22 homolog C, vesicle trafficking protein
chr6_+_169702185 4.86 ENST00000332290.3
chromosome 6 open reading frame 120
chr14_+_58637934 4.79 ENST00000395153.8
dishevelled binding antagonist of beta catenin 1
chr16_-_71577082 4.74 ENST00000355962.5
tyrosine aminotransferase
chr19_+_17215382 4.72 ENST00000595101.5
ENST00000596136.5
ENST00000445667.6
unconventional SNARE in the ER 1
chr11_-_62601818 4.69 ENST00000278823.7
metastasis associated 1 family member 2
chr5_-_78985249 4.65 ENST00000565165.2
arylsulfatase B
chr11_+_123525822 4.63 ENST00000322282.11
ENST00000529750.5
GRAM domain containing 1B
chr11_+_107591077 4.62 ENST00000531234.5
ENST00000265840.12
ELMO domain containing 1
chr11_-_89491320 4.57 ENST00000534731.5
ENST00000527626.5
ENST00000525196.5
ENST00000263317.9
NADPH oxidase 4
chr16_-_1793719 4.56 ENST00000415638.3
insulin like growth factor binding protein acid labile subunit
chr1_-_37554277 4.55 ENST00000296215.8
Smad nuclear interacting protein 1
chr12_+_104986292 4.54 ENST00000552951.7
ENST00000637147.1
ENST00000622317.5
ENST00000280749.5
chromosome 12 open reading frame 45
chr6_+_125781108 4.50 ENST00000368357.7
nuclear receptor coactivator 7
chr4_-_76213589 4.46 ENST00000638603.1
ENST00000452464.6
scavenger receptor class B member 2
chr2_-_144517663 4.36 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr6_-_88963409 4.35 ENST00000369475.7
ENST00000538899.2
RNA guanylyltransferase and 5'-phosphatase
chr14_+_79279339 4.30 ENST00000557594.5
neurexin 3
chr3_-_39051935 4.27 ENST00000668754.1
ENST00000302328.9
sodium voltage-gated channel alpha subunit 11
chr11_-_35360050 4.26 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chr19_-_38229654 4.22 ENST00000412732.5
ENST00000456296.5
double PHD fingers 1
chr17_+_39688079 4.13 ENST00000578199.5
erb-b2 receptor tyrosine kinase 2
chr2_+_171522227 4.12 ENST00000409484.5
cytochrome b reductase 1
chr21_+_39445824 4.02 ENST00000380637.7
ENST00000380634.5
ENST00000458295.5
ENST00000440288.6
ENST00000380631.5
SH3 domain binding glutamate rich protein
chr17_-_44830774 4.00 ENST00000590758.3
ENST00000591424.5
gap junction protein gamma 1
chr20_-_38165261 3.94 ENST00000361475.7
transglutaminase 2
chr2_-_219309350 3.93 ENST00000295718.7
protein tyrosine phosphatase receptor type N
chrX_-_44343611 3.83 ENST00000420999.2
EF-hand domain containing 2
chr19_+_41219235 3.83 ENST00000359092.7
AXL receptor tyrosine kinase
chr2_-_219309484 3.81 ENST00000409251.7
ENST00000451506.5
ENST00000446182.5
protein tyrosine phosphatase receptor type N
chr14_+_85530163 3.80 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chr11_+_73264479 3.75 ENST00000393592.7
ENST00000540342.6
ENST00000679753.1
ENST00000542092.5
ENST00000349767.6
pyrimidinergic receptor P2Y6
chr1_-_15976070 3.70 ENST00000537142.5
ENST00000375743.9
zinc finger and BTB domain containing 17
chr14_+_79279403 3.70 ENST00000281127.11
neurexin 3
chr1_+_26159071 3.66 ENST00000374268.5
family with sequence similarity 110 member D
chr2_+_10911924 3.64 ENST00000295082.3
potassium voltage-gated channel modifier subfamily F member 1
chr1_-_51331315 3.63 ENST00000262676.9
tetratricopeptide repeat domain 39A
chr1_+_100719734 3.58 ENST00000370119.8
ENST00000294728.7
ENST00000347652.6
ENST00000370115.1
vascular cell adhesion molecule 1
chr17_-_64130813 3.53 ENST00000606895.2
endoplasmic reticulum to nucleus signaling 1
chr12_-_48999363 3.48 ENST00000421952.3
dendrin
chr17_-_19386785 3.46 ENST00000497081.6
microfibril associated protein 4
chr16_-_1793694 3.44 ENST00000569769.1
ENST00000215539.4
splA/ryanodine receptor domain and SOCS box containing 3
insulin like growth factor binding protein acid labile subunit
chr16_-_66550112 3.43 ENST00000544898.6
ENST00000620035.5
ENST00000545043.6
thymidine kinase 2
chr14_+_79279906 3.42 ENST00000428277.6
neurexin 3
chr19_+_11538844 3.42 ENST00000252456.7
calponin 1
chr16_+_71626175 3.41 ENST00000268485.8
ENST00000565261.1
ENST00000299952.4
MARVEL domain containing 3
chr17_+_28473635 3.40 ENST00000314669.10
ENST00000545060.2
solute carrier family 13 member 2
chr17_-_6651557 3.38 ENST00000225728.8
ENST00000575197.1
mediator complex subunit 31
chr12_+_20695553 3.34 ENST00000545102.1
solute carrier organic anion transporter family member 1C1
chr14_+_21280077 3.30 ENST00000400017.7
RPGR interacting protein 1
chr18_+_34978244 3.25 ENST00000436190.6
microtubule associated protein RP/EB family member 2
chr11_-_63614425 3.24 ENST00000415826.3
phospholipase A and acyltransferase 3
chr12_-_21774688 3.15 ENST00000240662.3
potassium inwardly rectifying channel subfamily J member 8
chr5_-_178627001 3.13 ENST00000611575.4
ENST00000520957.1
ENST00000316308.9
ENST00000611733.4
CDC like kinase 4
chr2_+_161160299 3.13 ENST00000440506.5
ENST00000429217.5
ENST00000406287.5
ENST00000402568.5
TRAF family member associated NFKB activator
chr7_-_140640776 3.12 ENST00000275884.10
ENST00000475837.1
ENST00000496613.6
DENN domain containing 2A
chr9_-_121050264 3.11 ENST00000223642.3
complement C5
chr14_+_24398986 3.10 ENST00000382554.4
NYN domain and retroviral integrase containing
chr17_-_42112674 3.10 ENST00000251642.8
ENST00000591220.5
DExH-box helicase 58
chr2_+_137964446 3.03 ENST00000280096.5
ENST00000280097.5
histamine N-methyltransferase
chr5_-_115262851 3.02 ENST00000379615.3
ENST00000419445.6
protein geranylgeranyltransferase type I subunit beta
chr19_+_11538767 3.00 ENST00000592923.5
ENST00000535659.6
calponin 1
chr9_-_113221288 2.97 ENST00000446284.6
ENST00000414250.2
FKBP prolyl isomerase family member 15
chr6_-_70283105 2.90 ENST00000683980.1
collagen type IX alpha 1 chain
chr7_+_80602200 2.87 ENST00000534394.5
CD36 molecule
chr22_-_38181772 2.87 ENST00000430886.5
ENST00000667521.1
ENST00000663895.1
ENST00000402064.5
ENST00000332509.8
ENST00000664587.1
phospholipase A2 group VI
chr3_+_148739798 2.84 ENST00000402260.2
angiotensin II receptor type 1
chr5_-_157575741 2.83 ENST00000517905.1
ADAM metallopeptidase domain 19
chr6_+_44270434 2.78 ENST00000451188.7
transmembrane protein 151B
chr3_+_46370854 2.78 ENST00000292303.4
C-C motif chemokine receptor 5
chr2_+_171522466 2.78 ENST00000321348.9
ENST00000375252.3
cytochrome b reductase 1
chr3_+_50269140 2.78 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr20_+_32358303 2.76 ENST00000651418.1
ENST00000375687.10
ENST00000542461.5
ENST00000613218.4
ENST00000646367.1
ENST00000620121.4
ASXL transcriptional regulator 1
chr22_-_24245059 2.75 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
gamma-glutamyltransferase 5
chr7_-_142885737 2.72 ENST00000359396.9
ENST00000436401.1
transient receptor potential cation channel subfamily V member 6
chr2_+_176188658 2.70 ENST00000331462.6
homeobox D1
chr19_+_17215332 2.70 ENST00000263897.10
unconventional SNARE in the ER 1
chr17_-_7205116 2.70 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr15_+_70892809 2.67 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chrX_-_32155462 2.66 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr18_-_22417910 2.62 ENST00000391403.4
cutaneous T cell lymphoma-associated antigen 1
chr16_-_66550142 2.59 ENST00000417693.8
ENST00000299697.12
ENST00000451102.7
thymidine kinase 2
chr22_-_38181707 2.59 ENST00000668949.1
ENST00000335539.7
phospholipase A2 group VI
chr6_-_70283184 2.58 ENST00000320755.12
collagen type IX alpha 1 chain
chr9_+_117704168 2.57 ENST00000472304.2
ENST00000394487.5
toll like receptor 4
chr4_+_70242583 2.54 ENST00000304954.3
casein kappa
chr8_-_17697654 2.51 ENST00000297488.10
microtubule associated scaffold protein 1
chr1_-_193186599 2.50 ENST00000367434.5
beta-1,3-galactosyltransferase 2
chr1_-_13155961 2.49 ENST00000624207.1
PRAME family member 26
chr19_+_10420474 2.46 ENST00000380702.7
phosphodiesterase 4A
chr14_+_79279681 2.45 ENST00000679122.1
neurexin 3
chr6_-_28252246 2.45 ENST00000377294.3
zinc finger with KRAB and SCAN domains 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 39.1 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
5.6 16.9 GO:0097212 lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
4.5 13.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
4.2 12.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
3.6 10.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
3.2 9.5 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
2.6 7.7 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
2.2 15.4 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
2.0 6.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
2.0 7.9 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.9 9.5 GO:0072716 response to sorbitol(GO:0072708) response to actinomycin D(GO:0072716)
1.8 30.6 GO:0007021 tubulin complex assembly(GO:0007021)
1.8 12.3 GO:0072592 oxygen metabolic process(GO:0072592)
1.6 9.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
1.6 28.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.5 9.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.5 7.6 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.4 5.5 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
1.3 8.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
1.3 6.6 GO:2000542 negative regulation of gastrulation(GO:2000542)
1.3 6.6 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.3 23.3 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
1.2 11.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
1.1 11.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
1.0 9.4 GO:1902414 protein localization to cell junction(GO:1902414)
1.0 22.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
1.0 4.0 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.0 3.9 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.0 4.9 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.9 6.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.8 3.3 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.8 8.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.8 4.8 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.8 15.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.8 3.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.8 3.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.7 6.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.7 2.2 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.7 5.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.7 2.8 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.7 2.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.7 2.1 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.7 5.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.6 3.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.6 6.0 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.6 3.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.6 4.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.6 8.9 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.6 1.7 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.6 5.2 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6 5.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.5 4.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.5 1.6 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.5 4.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.5 4.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.5 3.0 GO:0001692 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.5 1.5 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.5 5.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.5 7.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.5 1.9 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.4 7.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 2.2 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.4 14.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.4 5.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 7.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 3.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 9.9 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.3 1.4 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.3 8.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 1.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 15.6 GO:0018149 peptide cross-linking(GO:0018149)
0.3 7.1 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.3 4.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 5.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.3 2.0 GO:0006824 cobalt ion transport(GO:0006824)
0.3 3.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 14.8 GO:0042417 dopamine metabolic process(GO:0042417)
0.3 0.6 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 0.8 GO:0001757 somite specification(GO:0001757)
0.3 2.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 2.8 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 2.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 9.5 GO:0048665 neuron fate specification(GO:0048665)
0.3 1.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 3.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 7.7 GO:0098743 cell aggregation(GO:0098743)
0.3 1.3 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.3 6.5 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.2 2.7 GO:2000821 regulation of grooming behavior(GO:2000821)
0.2 1.5 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.2 1.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.4 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 1.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 8.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 1.8 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.2 3.1 GO:0015074 DNA integration(GO:0015074)
0.2 2.7 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 2.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 2.7 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 14.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 21.9 GO:0007368 determination of left/right symmetry(GO:0007368)
0.2 0.7 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 6.9 GO:0010039 response to iron ion(GO:0010039)
0.2 4.7 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.2 11.5 GO:0010761 fibroblast migration(GO:0010761)
0.2 0.8 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 6.2 GO:0008089 anterograde axonal transport(GO:0008089)
0.2 18.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 0.8 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 5.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 5.1 GO:0006506 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.1 10.2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 2.2 GO:0007567 parturition(GO:0007567)
0.1 10.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.7 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.1 GO:0015816 glycine transport(GO:0015816)
0.1 1.1 GO:0030728 ovulation(GO:0030728)
0.1 4.3 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 1.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 7.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 3.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 8.5 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.1 1.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 2.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 9.4 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 0.4 GO:0060010 Sertoli cell fate commitment(GO:0060010) chondroblast differentiation(GO:0060591)
0.1 1.7 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 3.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 3.4 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 4.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.7 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 1.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.2 GO:0016540 protein autoprocessing(GO:0016540)
0.1 2.8 GO:0050919 negative chemotaxis(GO:0050919)
0.1 1.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 5.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 8.6 GO:0021915 neural tube development(GO:0021915)
0.1 5.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 6.2 GO:0005977 glycogen metabolic process(GO:0005977)
0.1 1.4 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 4.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 1.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.6 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) membrane depolarization during SA node cell action potential(GO:0086046)
0.0 1.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.8 GO:0001755 neural crest cell migration(GO:0001755) branching involved in salivary gland morphogenesis(GO:0060445)
0.0 6.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 4.3 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 2.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 11.4 GO:0032259 methylation(GO:0032259)
0.0 1.6 GO:0001570 vasculogenesis(GO:0001570)
0.0 3.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 8.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.3 GO:1904776 protein localization to cell cortex(GO:0072697) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.7 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 2.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 23.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
2.2 6.6 GO:0005588 collagen type V trimer(GO:0005588)
2.1 16.9 GO:0097450 astrocyte end-foot(GO:0097450)
1.9 30.6 GO:0097512 cardiac myofibril(GO:0097512)
1.8 5.3 GO:1990597 AIP1-IRE1 complex(GO:1990597)
1.3 7.7 GO:0005594 collagen type IX trimer(GO:0005594)
1.2 44.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.2 3.6 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.0 3.0 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.9 6.6 GO:0036021 endolysosome lumen(GO:0036021)
0.9 2.8 GO:0035517 PR-DUB complex(GO:0035517)
0.9 6.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.8 8.3 GO:0070852 cell body fiber(GO:0070852)
0.8 5.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.8 8.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.7 2.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.7 10.7 GO:0097433 dense body(GO:0097433)
0.7 3.4 GO:0070847 core mediator complex(GO:0070847)
0.7 3.3 GO:0044308 axonal spine(GO:0044308)
0.6 9.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.6 5.2 GO:0071953 elastic fiber(GO:0071953)
0.6 13.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 9.6 GO:0033643 host cell part(GO:0033643)
0.5 18.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4 10.5 GO:0035371 microtubule plus-end(GO:0035371)
0.4 3.1 GO:0005579 membrane attack complex(GO:0005579)
0.4 49.9 GO:0005604 basement membrane(GO:0005604)
0.4 11.4 GO:0043218 compact myelin(GO:0043218)
0.4 8.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.4 2.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 1.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.3 15.6 GO:0001533 cornified envelope(GO:0001533)
0.3 18.5 GO:0048786 presynaptic active zone(GO:0048786)
0.3 5.3 GO:0036038 MKS complex(GO:0036038)
0.3 10.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 4.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 2.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.2 4.0 GO:0005922 connexon complex(GO:0005922)
0.2 2.7 GO:0016013 syntrophin complex(GO:0016013)
0.2 3.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 30.0 GO:0043202 lysosomal lumen(GO:0043202)
0.2 3.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 4.7 GO:0032590 dendrite membrane(GO:0032590)
0.2 2.4 GO:0031209 SCAR complex(GO:0031209)
0.2 4.3 GO:0032589 neuron projection membrane(GO:0032589)
0.2 37.8 GO:0043209 myelin sheath(GO:0043209)
0.2 4.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 2.7 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.2 9.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 2.3 GO:0097060 synaptic membrane(GO:0097060)
0.1 14.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 8.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 4.2 GO:0071565 nBAF complex(GO:0071565)
0.1 17.1 GO:0043204 perikaryon(GO:0043204)
0.1 6.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 13.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.8 GO:0005871 kinesin complex(GO:0005871)
0.1 3.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 4.9 GO:0031201 SNARE complex(GO:0031201)
0.1 5.7 GO:0031526 brush border membrane(GO:0031526)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 7.1 GO:0005882 intermediate filament(GO:0005882)
0.1 10.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 18.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 4.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.2 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 1.4 GO:0005581 collagen trimer(GO:0005581)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 4.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 13.5 GO:0098793 presynapse(GO:0098793)
0.1 4.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 11.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 3.5 GO:0016234 inclusion body(GO:0016234)
0.0 5.1 GO:0030426 growth cone(GO:0030426)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 10.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 5.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 6.1 GO:0009986 cell surface(GO:0009986)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 4.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 3.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 23.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 16.8 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 39.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
3.9 23.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
3.2 38.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.8 8.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
2.5 12.3 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
2.0 6.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
1.9 5.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.6 14.7 GO:1903136 cuprous ion binding(GO:1903136)
1.6 4.7 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.5 13.5 GO:0034235 GPI anchor binding(GO:0034235)
1.4 8.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.3 16.9 GO:0046870 cadmium ion binding(GO:0046870)
1.3 10.3 GO:0045545 syndecan binding(GO:0045545)
1.2 8.1 GO:0001849 complement component C1q binding(GO:0001849)
1.2 8.1 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
1.1 6.9 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.1 3.4 GO:0030305 heparanase activity(GO:0030305)
1.1 3.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
1.1 9.9 GO:0097322 7SK snRNA binding(GO:0097322)
1.1 3.2 GO:0035375 zymogen binding(GO:0035375)
1.0 31.3 GO:0005212 structural constituent of eye lens(GO:0005212)
1.0 3.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.0 4.0 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.0 6.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.0 4.8 GO:0070097 delta-catenin binding(GO:0070097)
1.0 5.7 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.9 2.8 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.9 7.7 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.7 5.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 5.8 GO:0048495 Roundabout binding(GO:0048495)
0.6 9.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.6 0.6 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.6 17.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.6 3.7 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.6 5.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.6 3.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 11.1 GO:0045499 chemorepellent activity(GO:0045499)
0.5 4.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.5 8.9 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.5 9.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 6.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 1.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.4 7.1 GO:0019215 intermediate filament binding(GO:0019215)
0.4 3.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.4 3.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.4 4.1 GO:0001042 RNA polymerase I core binding(GO:0001042) ErbB-3 class receptor binding(GO:0043125)
0.4 3.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 5.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 1.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 1.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 1.6 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.3 1.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 2.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 10.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 4.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 8.2 GO:0001968 fibronectin binding(GO:0001968)
0.3 4.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.3 16.3 GO:0030507 spectrin binding(GO:0030507)
0.3 5.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 5.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 26.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 31.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 0.7 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.2 4.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 5.3 GO:0031005 filamin binding(GO:0031005)
0.2 2.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 14.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 2.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 3.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 2.3 GO:0046625 sphingolipid binding(GO:0046625)
0.2 2.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 1.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 2.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 2.8 GO:0038191 neuropilin binding(GO:0038191)
0.2 3.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 4.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 2.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 2.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 4.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 4.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 18.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 4.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 5.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.7 GO:1990239 steroid hormone binding(GO:1990239)
0.1 0.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.3 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 9.0 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.4 GO:0008009 chemokine activity(GO:0008009)
0.1 16.6 GO:0008017 microtubule binding(GO:0008017)
0.1 2.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 5.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 7.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 4.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 6.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 7.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 7.7 GO:0008168 methyltransferase activity(GO:0008168)
0.0 8.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 7.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 2.3 GO:0019838 growth factor binding(GO:0019838)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 14.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 15.0 GO:0008270 zinc ion binding(GO:0008270)
0.0 5.5 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 7.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.5 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 23.5 GO:0046872 metal ion binding(GO:0046872)
0.0 3.7 GO:0003779 actin binding(GO:0003779)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 33.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.7 40.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 93.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 15.4 NABA COLLAGENS Genes encoding collagen proteins
0.2 12.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 29.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 6.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 4.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 8.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.7 PID MYC PATHWAY C-MYC pathway
0.1 4.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 7.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 23.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.1 53.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.8 9.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.7 11.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.7 15.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.6 8.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 14.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.5 8.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 8.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.5 6.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.5 9.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.5 2.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 8.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 5.3 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.3 8.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 5.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 15.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 5.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 4.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 10.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 8.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 3.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 6.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 6.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 3.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 4.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 5.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 2.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 5.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 0.6 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 1.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 5.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 3.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.9 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 1.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)