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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZNF711_TFAP2A_TFAP2D

Z-value: 10.02

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Transcription factors associated with ZNF711_TFAP2A_TFAP2D

Gene Symbol Gene ID Gene Info
ENSG00000147180.17 ZNF711
ENSG00000137203.15 TFAP2A
ENSG00000008197.5 TFAP2D

Activity-expression correlation:

Activity profile of ZNF711_TFAP2A_TFAP2D motif

Sorted Z-values of ZNF711_TFAP2A_TFAP2D motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF711_TFAP2A_TFAP2D

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_1309714 161.00 ENST00000566587.5
ubiquitin conjugating enzyme E2 I
chr2_-_10448318 126.17 ENST00000234111.9
ornithine decarboxylase 1
chr15_-_60397964 114.70 ENST00000558998.5
ENST00000560165.5
ENST00000557986.5
ENST00000559467.5
ENST00000677968.1
ENST00000678450.1
ENST00000332680.8
ENST00000396024.7
ENST00000557906.6
ENST00000558558.6
ENST00000559113.6
ENST00000559780.6
ENST00000559956.6
ENST00000560468.6
ENST00000678870.1
ENST00000678061.1
ENST00000451270.7
ENST00000421017.6
ENST00000560466.5
ENST00000558132.5
ENST00000559370.5
ENST00000559725.5
ENST00000558985.6
ENST00000679109.1
annexin A2
chr19_-_55407719 103.79 ENST00000587845.5
ENST00000589978.1
ENST00000264552.14
ubiquitin conjugating enzyme E2 S
chr10_-_32957865 103.49 ENST00000437302.6
ENST00000396033.6
integrin subunit beta 1
chr6_-_7910776 99.88 ENST00000379757.9
thioredoxin domain containing 5
chrX_-_154019800 98.14 ENST00000444230.5
ENST00000393687.6
ENST00000429936.6
ENST00000369974.6
ENST00000369980.8
interleukin 1 receptor associated kinase 1
chr21_-_17612842 96.53 ENST00000339775.10
ENST00000348354.7
BTG anti-proliferation factor 3
chr15_-_90994494 96.38 ENST00000559811.1
ENST00000442656.6
ENST00000557905.5
ENST00000394249.8
protein regulator of cytokinesis 1
chr16_-_88785210 94.89 ENST00000301015.14
piezo type mechanosensitive ion channel component 1
chr3_+_172040554 94.08 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chrX_+_49171918 87.82 ENST00000376322.7
proteolipid protein 2
chr1_+_155208690 86.48 ENST00000368376.8
metaxin 1
chr5_-_10761156 84.96 ENST00000432074.2
ENST00000230895.11
death associated protein
chr20_-_62143374 84.94 ENST00000370873.9
ENST00000370858.3
proteasome 20S subunit alpha 7
chr1_-_152036984 84.08 ENST00000271638.3
S100 calcium binding protein A11
chr11_-_2929412 83.75 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr4_-_1712250 83.69 ENST00000318386.8
stem-loop binding protein
chr16_-_85799554 83.33 ENST00000435200.2
ER membrane protein complex subunit 8
chr12_+_104215772 82.72 ENST00000429002.6
ENST00000525566.6
thioredoxin reductase 1
chr2_-_10447771 82.28 ENST00000405333.5
ENST00000443218.1
ornithine decarboxylase 1
chr2_-_105398978 82.27 ENST00000408995.5
ENST00000530340.6
ENST00000393353.7
ENST00000322142.13
ENST00000344213.9
ENST00000358129.8
four and a half LIM domains 2
chr6_-_13814490 81.79 ENST00000379170.8
mitochondrial calcium uniporter regulator 1
chr5_-_134004635 79.84 ENST00000425992.2
ENST00000395044.7
ENST00000395047.6
voltage dependent anion channel 1
chr2_+_234952009 79.83 ENST00000392011.7
SH3 domain binding protein 4
chr11_+_1947278 78.91 ENST00000381519.5
ENST00000397298.8
ENST00000397297.7
ENST00000381514.7
ENST00000397294.7
mitochondrial ribosomal protein L23
chr17_-_75153826 78.74 ENST00000481647.5
ENST00000470924.5
Jupiter microtubule associated homolog 1
chr12_-_108731505 78.46 ENST00000261401.8
ENST00000552871.5
coronin 1C
chr8_-_140635617 77.80 ENST00000220592.10
argonaute RISC catalytic component 2
chr1_+_40979659 77.00 ENST00000650070.2
ENST00000649864.1
ENST00000649124.1
CTP synthase 1
chr5_+_172983763 76.48 ENST00000519374.6
ENST00000519911.5
ATPase H+ transporting V0 subunit e1
chr4_-_1712310 76.03 ENST00000488267.5
ENST00000429429.6
ENST00000489418.6
ENST00000480936.1
stem-loop binding protein
chr16_-_85799503 74.59 ENST00000253457.8
ER membrane protein complex subunit 8
chr11_-_14359118 74.39 ENST00000256196.9
RAS related 2
chr22_+_43151931 74.01 ENST00000329563.8
ENST00000396265.4
translocator protein
chr6_-_158644709 73.16 ENST00000367089.8
dynein light chain Tctex-type 1
chr9_+_89311187 72.32 ENST00000314355.7
CDC28 protein kinase regulatory subunit 2
chr16_-_87869497 71.47 ENST00000261622.5
solute carrier family 7 member 5
chr4_+_109560219 70.86 ENST00000394650.7
mitochondrial calcium uniporter dominant negative subunit beta
chr4_-_184734059 70.59 ENST00000281453.10
centromere protein U
chrX_-_154374623 69.83 ENST00000369850.10
filamin A
chrX_-_153724343 69.47 ENST00000442093.5
ENST00000345046.12
ENST00000645377.1
ENST00000672675.1
ENST00000647529.1
ENST00000429550.5
B cell receptor associated protein 31
chr1_+_224356852 68.12 ENST00000366858.7
ENST00000366857.9
ENST00000465271.6
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chrX_+_119468436 67.77 ENST00000317881.9
solute carrier family 25 member 5
chr22_-_50307598 67.70 ENST00000425954.1
ENST00000449103.5
ENST00000359337.9
plexin B2
chr7_-_100100716 67.07 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chrX_-_153724044 66.93 ENST00000423827.5
ENST00000458587.8
B cell receptor associated protein 31
chr6_-_18264475 66.56 ENST00000515742.2
ENST00000651624.1
ENST00000507591.2
ENST00000652689.1
ENST00000244776.11
ENST00000503715.5
DEK proto-oncogene
chr3_-_53256009 66.55 ENST00000296289.10
ENST00000462138.6
ENST00000423516.5
transketolase
chr4_-_173333672 66.25 ENST00000438704.6
high mobility group box 2
chr15_+_80060113 65.94 ENST00000618205.4
zinc finger AN1-type containing 6
chr1_+_236395394 65.91 ENST00000359362.6
EDAR associated death domain
chr5_+_72816643 65.88 ENST00000337273.10
ENST00000523768.5
transportin 1
chr16_+_1309621 65.85 ENST00000397515.6
ENST00000397514.8
ENST00000567383.6
ENST00000403747.6
ubiquitin conjugating enzyme E2 I
chr5_+_171387757 65.84 ENST00000677297.1
ENST00000521672.6
ENST00000679190.1
ENST00000351986.10
ENST00000676589.1
ENST00000679233.1
ENST00000677357.1
ENST00000296930.10
ENST00000393820.2
ENST00000523622.1
nucleophosmin 1
chr18_+_32091849 65.75 ENST00000261593.8
ENST00000578914.1
ring finger protein 138
chr16_-_50368779 65.68 ENST00000394689.2
bromodomain containing 7
chrX_+_132023294 65.55 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chr13_-_98577131 65.05 ENST00000397517.6
serine/threonine kinase 24
chr3_-_67654582 65.00 ENST00000492795.1
ENST00000493112.5
ENST00000307227.10
succinate-CoA ligase GDP-forming subunit beta
chr21_-_39183398 64.89 ENST00000331573.8
proteasome assembly chaperone 1
chr1_+_223712491 64.84 ENST00000295006.6
calpain 2
chr1_-_93909329 64.79 ENST00000370238.8
ENST00000615724.1
glutamate-cysteine ligase modifier subunit
chrX_-_154366334 64.65 ENST00000673639.2
filamin A
chrX_+_65667645 64.53 ENST00000360270.7
moesin
chr1_+_228082660 63.95 ENST00000540651.5
ENST00000272102.10
ADP ribosylation factor 1
chrX_+_21940693 63.75 ENST00000404933.7
ENST00000379404.5
spermine synthase
chr2_+_69741974 63.19 ENST00000409920.5
annexin A4
chr1_+_86704892 62.57 ENST00000482504.1
SH3 domain containing GRB2 like, endophilin B1
chr16_-_29454964 62.41 ENST00000330978.3
bolA family member 2
chrX_+_154762729 62.37 ENST00000620277.4
dyskerin pseudouridine synthase 1
chr21_-_43776238 62.21 ENST00000639959.1
ENST00000291568.7
ENST00000640406.1
cystatin B
chr11_+_86800527 62.17 ENST00000280258.6
serine protease 23
chr1_+_155208727 62.14 ENST00000316721.8
metaxin 1
chr3_+_184361677 61.91 ENST00000456318.5
ENST00000412877.1
ENST00000438240.5
RNA polymerase II, I and III subunit H
chr7_+_2354810 61.72 ENST00000360876.9
ENST00000413917.5
ENST00000397011.2
eukaryotic translation initiation factor 3 subunit B
chr17_+_68035722 61.69 ENST00000679078.1
ENST00000330459.8
ENST00000584026.6
karyopherin subunit alpha 2
chr2_+_84971093 61.61 ENST00000456682.1
ENST00000409785.9
potassium channel modulatory factor 1
chr2_+_10122730 61.60 ENST00000304567.10
ribonucleotide reductase regulatory subunit M2
chr14_+_55580196 61.24 ENST00000395314.8
ENST00000554567.1
ENST00000555498.5
ENST00000438792.6
ENST00000395308.5
kinectin 1
chr10_-_5889832 61.06 ENST00000380092.8
ENST00000380094.10
ENST00000191063.8
ankyrin repeat domain 16
chr2_-_10812794 60.90 ENST00000540494.5
protein disulfide isomerase family A member 6
chr18_+_158513 60.55 ENST00000400266.7
ENST00000580410.5
ENST00000261601.8
ENST00000383589.6
ubiquitin specific peptidase 14
chr11_-_14358450 60.53 ENST00000526063.5
ENST00000532814.5
RAS related 2
chr3_+_33114033 60.42 ENST00000449224.1
cartilage associated protein
chr5_+_138753412 60.39 ENST00000520339.5
ENST00000627109.2
ENST00000302763.12
ENST00000518910.5
catenin alpha 1
chr5_+_74685225 60.25 ENST00000261416.12
hexosaminidase subunit beta
chr17_-_75154503 60.23 ENST00000409753.8
ENST00000581874.1
Jupiter microtubule associated homolog 1
chr8_+_90001448 60.23 ENST00000519410.5
ENST00000522161.5
ENST00000220764.7
ENST00000517761.5
ENST00000520227.1
2,4-dienoyl-CoA reductase 1
chr3_-_53255990 60.19 ENST00000423525.6
transketolase
chr22_-_17159220 60.06 ENST00000399852.3
ENST00000336737.8
haloacid dehalogenase like hydrolase domain containing 5
chr8_+_144354640 59.94 ENST00000532815.2
solute carrier family 52 member 2
chr16_-_66830903 59.68 ENST00000566336.5
ENST00000394074.6
ENST00000563185.6
ENST00000359087.8
ENST00000290810.8
ENST00000379463.6
ENST00000565535.5
NEDD8 activating enzyme E1 subunit 1
chr8_+_144095054 59.51 ENST00000318911.5
cytochrome c1
chr17_+_1829981 59.40 ENST00000254719.10
replication protein A1
chr12_-_76084666 59.40 ENST00000393263.7
ENST00000548044.5
ENST00000547704.5
ENST00000618691.5
ENST00000431879.7
ENST00000549596.5
ENST00000550934.5
ENST00000551600.5
ENST00000547479.5
ENST00000547773.5
ENST00000544816.5
ENST00000542344.5
ENST00000548273.5
nucleosome assembly protein 1 like 1
chr17_+_68035636 59.36 ENST00000676857.1
ENST00000676594.1
ENST00000678388.1
karyopherin subunit alpha 2
chr21_+_46098102 59.33 ENST00000300527.9
ENST00000310645.9
collagen type VI alpha 2 chain
chr4_+_109433772 59.30 ENST00000504968.6
ENST00000399100.6
ENST00000265175.5
SEC24 homolog B, COPII coat complex component
chr7_+_12686849 59.27 ENST00000396662.5
ENST00000356797.7
ENST00000396664.2
ADP ribosylation factor like GTPase 4A
chr15_-_63157991 59.13 ENST00000411926.1
ribosomal protein S27 like
chr12_-_76084612 58.85 ENST00000535020.6
ENST00000552342.5
nucleosome assembly protein 1 like 1
chr5_-_151080978 58.83 ENST00000520931.5
ENST00000521591.6
ENST00000520695.5
ENST00000610535.5
ENST00000518977.5
ENST00000389378.6
ENST00000610874.4
TNFAIP3 interacting protein 1
chr5_+_172983789 58.72 ENST00000265093.4
ENST00000517669.1
ATPase H+ transporting V0 subunit e1
chr2_+_27211992 58.59 ENST00000380171.8
ENST00000611786.4
all-trans retinoic acid induced differentiation factor
chr7_+_816609 58.54 ENST00000457378.6
ENST00000389574.7
ENST00000452783.6
ENST00000435699.5
ENST00000440380.5
ENST00000439679.5
ENST00000424128.5
Sad1 and UNC84 domain containing 1
chr7_+_16646131 57.99 ENST00000415365.5
ENST00000433922.6
ENST00000630952.2
ENST00000258761.8
ENST00000405202.5
basic leucine zipper and W2 domains 2
chr17_-_75182536 57.94 ENST00000578238.2
small ubiquitin like modifier 2
chr7_-_105522204 57.85 ENST00000356362.6
pseudouridine synthase 7
chr22_+_20116099 57.73 ENST00000430524.6
RAN binding protein 1
chr18_-_9614518 57.62 ENST00000400556.8
ENST00000400555.7
protein phosphatase 4 regulatory subunit 1
chr8_-_86514332 57.57 ENST00000523911.5
regulator of microtubule dynamics 1
chr20_+_63739751 57.53 ENST00000266077.5
SLC2A4 regulator
chr11_-_14643617 57.45 ENST00000418988.2
proteasome 20S subunit alpha 1
chr1_-_8879170 56.99 ENST00000489867.2
enolase 1
chr1_-_8878706 56.87 ENST00000646156.1
enolase 1
chr5_+_178204522 56.77 ENST00000506339.5
ENST00000358344.8
ENST00000355836.9
ENST00000514633.5
ENST00000515193.5
ENST00000506259.5
ENST00000504898.5
heterogeneous nuclear ribonucleoprotein A/B
chr19_+_32581178 56.76 ENST00000590247.7
ENST00000419343.7
ENST00000592786.5
ENST00000379316.3
programmed cell death 5
chr2_-_214809650 56.69 ENST00000260947.9
ENST00000613706.5
BRCA1 associated RING domain 1
chr5_-_69369465 56.68 ENST00000508954.3
ENST00000512152.5
ENST00000503245.5
ENST00000217893.10
ENST00000618980.1
ENST00000502819.5
ENST00000380822.9
ENST00000512561.5
TATA-box binding protein associated factor 9
adenylate kinase 6
chr7_+_99374675 56.65 ENST00000645391.1
ENST00000455009.6
actin related protein 2/3 complex subunit 1B
chr8_+_22579139 56.58 ENST00000397761.6
PDZ and LIM domain 2
chr14_-_105021043 56.55 ENST00000392590.3
ENST00000336219.4
cell division cycle associated 4
chr1_+_98661666 56.45 ENST00000529992.5
sorting nexin 7
chr1_+_179082025 56.33 ENST00000367625.8
ENST00000367627.8
ENST00000352445.10
torsin family 3 member A
chr11_+_61792878 56.28 ENST00000305885.3
ENST00000535723.1
flap structure-specific endonuclease 1
chr11_-_64246907 56.21 ENST00000309318.8
protein phosphatase 1 regulatory inhibitor subunit 14B
chr2_+_69742125 55.81 ENST00000394295.6
annexin A4
chr1_+_98661709 55.65 ENST00000306121.8
sorting nexin 7
chr12_+_95858928 55.60 ENST00000266735.9
ENST00000553192.5
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr16_-_11586941 55.52 ENST00000571976.1
ENST00000413364.6
lipopolysaccharide induced TNF factor
chr19_+_572529 55.45 ENST00000679472.1
ENST00000680552.1
ENST00000680065.1
ENST00000573216.5
basigin (Ok blood group)
chr2_+_10123171 55.42 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr11_-_107858777 55.39 ENST00000525815.6
solute carrier family 35 member F2
chr16_-_50368920 55.38 ENST00000394688.8
bromodomain containing 7
chr2_-_208254232 55.37 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chr1_+_201982613 55.25 ENST00000295640.9
ENST00000367286.7
arginyl aminopeptidase
chr1_-_23800402 55.21 ENST00000374497.7
ENST00000425913.5
UDP-galactose-4-epimerase
chr8_-_101205455 55.19 ENST00000520984.5
zinc finger protein 706
chr6_-_109382397 54.63 ENST00000512821.5
CD164 molecule
chr11_+_110429898 54.59 ENST00000260270.3
ferredoxin 1
chr9_+_130835246 54.57 ENST00000318560.6
ABL proto-oncogene 1, non-receptor tyrosine kinase
chr7_+_32957385 54.56 ENST00000538336.5
ENST00000242209.9
FKBP prolyl isomerase 9
chr1_-_8878018 54.45 ENST00000646660.1
ENST00000646906.1
enolase 1
chr1_+_62437015 54.25 ENST00000339950.5
ubiquitin specific peptidase 1
chrX_+_154444121 54.21 ENST00000393600.8
family with sequence similarity 50 member A
chr1_-_67833448 53.98 ENST00000370982.4
G protein subunit gamma 12
chr10_+_79347460 53.91 ENST00000225174.8
peptidylprolyl isomerase F
chr1_+_43358968 53.83 ENST00000310955.11
cell division cycle 20
chr6_-_169724467 53.80 ENST00000339209.9
PHD finger protein 10
chr11_+_65919687 53.77 ENST00000532933.1
DR1 associated protein 1
chr8_+_22579100 53.63 ENST00000452226.5
ENST00000397760.8
PDZ and LIM domain 2
chr4_-_70839343 53.58 ENST00000514161.5
ENST00000499044.6
G-rich RNA sequence binding factor 1
chr3_+_52705828 53.57 ENST00000233025.11
signal peptidase complex subunit 1
chr19_-_1095261 53.55 ENST00000585838.2
ENST00000586746.5
ENST00000619917.4
ENST00000615234.5
ENST00000612655.4
RNA polymerase II, I and III subunit E
chr7_-_105522264 53.49 ENST00000469408.6
pseudouridine synthase 7
chr2_-_43995999 53.47 ENST00000683213.1
ENST00000409946.6
leucine rich pentatricopeptide repeat containing
chr8_-_27838034 53.40 ENST00000522944.5
PDZ binding kinase
chr16_-_11586903 53.37 ENST00000571459.5
ENST00000570798.5
ENST00000622633.5
ENST00000572255.5
ENST00000574763.5
ENST00000574703.5
ENST00000571277.1
lipopolysaccharide induced TNF factor
chr1_+_155209213 53.27 ENST00000609421.1
metaxin 1
chr16_+_89948697 53.23 ENST00000567999.5
ENST00000610455.4
ENST00000617948.4
ENST00000566079.5
ENST00000566820.5
ENST00000562578.5
ENST00000563594.6
ENST00000561741.5
ENST00000268676.11
ENST00000562986.5
ENST00000569453.5
ENST00000567884.5
ENST00000569061.5
ENST00000418391.6
ENST00000561959.5
ENST00000567874.5
ENST00000570182.5
ENST00000563795.1
differentially expressed in FDCP 8 homolog
chrX_-_154371210 53.21 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr5_-_69369257 53.19 ENST00000509462.5
TATA-box binding protein associated factor 9
chr8_-_70607654 53.08 ENST00000521425.5
translocation associated membrane protein 1
chr3_-_196082078 53.05 ENST00000360110.9
ENST00000392396.7
ENST00000420415.5
transferrin receptor
chr12_-_76083926 53.04 ENST00000551992.5
nucleosome assembly protein 1 like 1
chr3_-_63863791 52.98 ENST00000464327.2
ENST00000295899.10
ENST00000469584.5
THO complex 7
chr20_+_64255728 52.94 ENST00000369758.8
ENST00000308824.11
ENST00000609372.1
ENST00000610196.1
ENST00000609764.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr13_-_98577094 52.93 ENST00000539966.6
serine/threonine kinase 24
chr3_-_177197429 52.86 ENST00000457928.7
TBL1X receptor 1
chr18_+_657734 52.80 ENST00000323250.9
ENST00000323224.7
thymidylate synthetase
chr6_-_4135459 52.74 ENST00000495548.1
ENST00000380125.6
ENST00000465828.5
ENST00000380118.8
ENST00000361538.6
enoyl-CoA delta isomerase 2
chr1_-_150974823 52.51 ENST00000361419.9
ENST00000368954.10
ceramide synthase 2
chr18_+_11981488 52.50 ENST00000269159.8
inositol monophosphatase 2
chr4_+_1721470 52.43 ENST00000612220.5
ENST00000313288.9
transforming acidic coiled-coil containing protein 3
chr4_-_156971769 52.28 ENST00000502773.6
platelet derived growth factor C
chr3_+_184362599 52.21 ENST00000455712.5
RNA polymerase II, I and III subunit H
chr9_-_109013483 52.09 ENST00000325551.9
ENST00000374593.4
ENST00000374595.8
catenin alpha like 1
chr8_-_143617457 52.07 ENST00000529048.5
ENST00000529064.5
GDP-L-fucose synthase
chr17_-_82065783 52.05 ENST00000578907.5
ENST00000577907.1
ENST00000578176.5
ENST00000306796.10
ENST00000582529.5
dihydrouridine synthase 1 like
chr3_-_64023424 52.02 ENST00000478185.1
ENST00000482510.5
ENST00000497323.5
ENST00000492933.5
ENST00000295901.9
proteasome 26S subunit, non-ATPase 6
chr15_+_41332862 51.99 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chrX_+_2691270 51.99 ENST00000381187.8
ENST00000381184.6
CD99 molecule (Xg blood group)
chr22_+_43151871 51.95 ENST00000428336.5
translocator protein
chr22_-_19178719 51.95 ENST00000215882.10
solute carrier family 25 member 1
chr15_-_90234046 51.88 ENST00000612800.1
calcium and integrin binding 1
chr2_+_10122315 51.81 ENST00000360566.6
ribonucleotide reductase regulatory subunit M2
chr1_-_94237562 51.79 ENST00000260526.11
ENST00000370217.3
Rho GTPase activating protein 29
chr11_+_747411 51.60 ENST00000528097.5
ENST00000319006.8
transaldolase 1
chr14_+_58244821 51.56 ENST00000216455.9
ENST00000412908.6
ENST00000557508.5
proteasome 20S subunit alpha 3
chr2_-_214809597 51.53 ENST00000619009.5
ENST00000421162.2
ENST00000617164.5
ENST00000613374.5
ENST00000620057.4
BRCA1 associated RING domain 1
chr13_-_113208634 51.48 ENST00000375457.2
ENST00000375477.5
ENST00000337344.9
ENST00000246505.9
ENST00000622406.4
ENST00000375479.6
PCI domain containing 2
chr4_-_173334249 51.46 ENST00000506267.1
ENST00000296503.10
high mobility group box 2
chr3_-_131502946 51.36 ENST00000512877.1
ENST00000264995.8
ENST00000511168.5
ENST00000425847.6
mitochondrial ribosomal protein L3
chr5_-_1523900 51.33 ENST00000283415.4
lysophosphatidylcholine acyltransferase 1
chr10_-_95290992 51.25 ENST00000329399.7
PDZ and LIM domain 1
chr15_+_78540729 51.24 ENST00000559365.5
ENST00000558341.5
ENST00000559437.5
proteasome 20S subunit alpha 4
chrX_+_23667461 51.24 ENST00000379341.9
ENST00000379331.3
peroxiredoxin 4
chr9_-_136866265 51.06 ENST00000371648.4
ENST00000371649.5
endothelial differentiation related factor 1
chr15_+_80059651 51.02 ENST00000561012.5
ENST00000261749.11
ENST00000564367.5
ENST00000558494.5
zinc finger AN1-type containing 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
63.5 254.0 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
62.6 187.7 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
59.4 178.3 GO:0005999 xylulose biosynthetic process(GO:0005999)
55.3 276.6 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
46.9 46.9 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
43.0 171.8 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
40.9 122.8 GO:0090669 telomerase RNA stabilization(GO:0090669)
40.5 161.9 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
39.0 116.9 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
36.9 36.9 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
36.0 108.1 GO:0006097 glyoxylate cycle(GO:0006097)
35.6 106.9 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
35.5 106.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
35.2 105.6 GO:0006226 dUMP biosynthetic process(GO:0006226)
34.9 174.7 GO:0044111 development involved in symbiotic interaction(GO:0044111)
33.6 67.3 GO:0019322 pentose biosynthetic process(GO:0019322)
33.6 100.9 GO:1903976 negative regulation of glial cell migration(GO:1903976)
33.5 100.4 GO:1902822 regulation of late endosome to lysosome transport(GO:1902822)
33.1 198.6 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
32.7 196.5 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
32.6 130.4 GO:1904045 cellular response to aldosterone(GO:1904045)
32.5 130.0 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
32.2 96.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
32.0 96.0 GO:0070476 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
31.8 95.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
31.6 94.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
31.5 94.6 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
31.0 93.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
30.6 122.3 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
30.4 121.8 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
30.3 91.0 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
30.2 120.8 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
29.6 88.8 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
29.5 117.8 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
29.4 88.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
29.1 116.5 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
28.4 113.5 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
28.4 226.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
27.4 82.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
27.2 108.9 GO:1901873 regulation of post-translational protein modification(GO:1901873)
26.6 79.7 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
26.2 157.3 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
26.1 182.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
26.0 415.9 GO:0043248 proteasome assembly(GO:0043248)
26.0 52.0 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
26.0 155.7 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
25.9 51.8 GO:0046086 adenosine biosynthetic process(GO:0046086)
25.9 77.6 GO:0097069 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
25.2 25.2 GO:0010040 response to iron(II) ion(GO:0010040)
25.2 352.5 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
24.8 222.9 GO:0006265 DNA topological change(GO:0006265)
24.5 98.0 GO:0090095 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
24.5 48.9 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
24.3 121.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
24.3 72.8 GO:0009786 regulation of asymmetric cell division(GO:0009786)
24.2 120.8 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
24.1 192.6 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
24.0 120.0 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
23.7 260.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
23.5 93.9 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
23.3 140.0 GO:0006021 inositol biosynthetic process(GO:0006021)
23.1 92.4 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
23.0 161.0 GO:0032218 riboflavin transport(GO:0032218)
22.7 158.9 GO:0001922 B-1 B cell homeostasis(GO:0001922)
22.5 135.0 GO:0010266 response to vitamin B1(GO:0010266)
22.3 44.6 GO:0006458 'de novo' protein folding(GO:0006458)
22.3 89.2 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
22.2 155.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
22.1 199.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
21.9 153.0 GO:0030421 defecation(GO:0030421)
21.8 65.5 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
21.8 87.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
21.8 21.8 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
21.8 21.8 GO:0030043 actin filament fragmentation(GO:0030043)
21.6 86.5 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
21.5 21.5 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
21.4 42.8 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
21.4 64.1 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
21.3 127.8 GO:0075525 viral translational termination-reinitiation(GO:0075525)
21.3 85.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
21.1 147.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
21.0 188.8 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
20.9 293.1 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
20.9 41.8 GO:0009180 nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
20.9 20.9 GO:0043504 mitochondrial DNA repair(GO:0043504)
20.8 62.4 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
20.8 62.4 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
20.7 123.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
20.6 61.8 GO:0006117 acetaldehyde metabolic process(GO:0006117)
20.6 102.8 GO:0015862 uridine transport(GO:0015862)
20.5 82.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
20.5 102.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
20.4 122.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
20.4 102.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
20.3 60.8 GO:0046292 formaldehyde metabolic process(GO:0046292)
20.2 80.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
20.1 140.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
20.0 60.0 GO:0001923 B-1 B cell differentiation(GO:0001923)
19.9 79.5 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
19.8 39.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
19.7 118.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
19.7 78.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
19.5 234.0 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
19.5 97.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
19.5 155.7 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
19.5 116.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
19.4 97.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
19.4 96.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
19.2 76.7 GO:0043335 protein unfolding(GO:0043335)
19.1 57.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
19.0 38.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
18.9 113.7 GO:0022614 membrane to membrane docking(GO:0022614)
18.9 56.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
18.8 131.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
18.5 407.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
18.5 406.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
18.4 18.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
18.3 18.3 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
18.2 18.2 GO:0006106 fumarate metabolic process(GO:0006106)
18.2 145.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
18.1 126.9 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
18.0 36.0 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
18.0 144.0 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
17.9 53.6 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
17.8 53.5 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
17.8 35.5 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
17.8 35.5 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
17.7 88.7 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
17.7 17.7 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
17.7 53.0 GO:0071038 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
17.6 70.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
17.4 173.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
17.3 138.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
17.2 69.0 GO:0006167 AMP biosynthetic process(GO:0006167)
17.2 103.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
17.1 68.5 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
17.1 85.3 GO:0006177 GMP biosynthetic process(GO:0006177)
17.0 255.7 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
17.0 119.0 GO:0045047 protein targeting to ER(GO:0045047)
17.0 34.0 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
17.0 67.9 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
17.0 84.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
16.9 50.6 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
16.9 50.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
16.8 168.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
16.8 50.5 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
16.8 50.5 GO:0006059 hexitol metabolic process(GO:0006059)
16.8 218.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
16.8 67.0 GO:0032262 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
16.7 50.1 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
16.7 133.3 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
16.7 50.0 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
16.7 50.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
16.4 65.5 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
16.4 1471.7 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
16.2 16.2 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
16.2 16.2 GO:1903911 positive regulation of receptor clustering(GO:1903911)
16.1 112.9 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
16.0 224.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
16.0 32.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
16.0 95.9 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
16.0 47.9 GO:1903382 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
15.8 15.8 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
15.8 15.8 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
15.7 47.0 GO:1902905 positive regulation of fibril organization(GO:1902905)
15.7 15.7 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
15.6 31.2 GO:0015853 adenine transport(GO:0015853)
15.6 62.4 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
15.6 62.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
15.5 46.6 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
15.5 46.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
15.4 15.4 GO:1903826 arginine transmembrane transport(GO:1903826)
15.4 15.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
15.3 153.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
15.3 30.5 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
15.2 152.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
15.2 60.8 GO:0030047 actin modification(GO:0030047)
15.2 15.2 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
15.1 60.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
14.9 134.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
14.9 44.8 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
14.9 59.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
14.9 134.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
14.8 44.5 GO:0009438 methylglyoxal metabolic process(GO:0009438)
14.7 58.9 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
14.7 132.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
14.7 44.0 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
14.6 102.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
14.6 29.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
14.6 43.8 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
14.5 87.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
14.5 101.7 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
14.5 29.0 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
14.5 14.5 GO:0015780 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
14.4 186.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
14.4 28.7 GO:0044375 regulation of peroxisome size(GO:0044375)
14.3 85.7 GO:0097052 L-kynurenine metabolic process(GO:0097052)
14.3 171.3 GO:0019388 galactose catabolic process(GO:0019388)
14.3 57.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
14.1 183.9 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
14.1 84.8 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
14.1 42.4 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
14.1 14.1 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
14.1 84.4 GO:0016321 female meiosis chromosome segregation(GO:0016321)
14.1 70.3 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
14.1 84.3 GO:2000561 CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
14.0 14.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
14.0 336.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
14.0 84.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
13.8 82.9 GO:1903332 regulation of protein folding(GO:1903332)
13.8 55.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
13.8 27.6 GO:0007113 endomitotic cell cycle(GO:0007113)
13.8 1048.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
13.8 82.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
13.8 55.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
13.8 82.6 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
13.8 137.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
13.7 13.7 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
13.7 68.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
13.6 13.6 GO:0071888 macrophage apoptotic process(GO:0071888)
13.6 27.2 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
13.6 68.0 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
13.6 81.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
13.6 40.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
13.6 40.7 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
13.5 13.5 GO:2000850 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
13.5 13.5 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
13.5 53.8 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
13.5 40.4 GO:0035732 nitric oxide storage(GO:0035732)
13.4 40.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
13.4 53.6 GO:0009838 abscission(GO:0009838)
13.3 13.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
13.3 80.0 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
13.3 13.3 GO:0033206 meiotic cytokinesis(GO:0033206)
13.3 39.8 GO:0035026 leading edge cell differentiation(GO:0035026)
13.2 39.7 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
13.2 52.9 GO:0006344 maintenance of chromatin silencing(GO:0006344)
13.2 552.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
13.0 13.0 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
13.0 39.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
12.9 64.6 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
12.9 12.9 GO:0033182 regulation of histone ubiquitination(GO:0033182)
12.8 25.6 GO:0072019 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
12.8 25.6 GO:0019087 transformation of host cell by virus(GO:0019087)
12.8 38.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
12.8 12.8 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
12.7 38.2 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
12.7 25.5 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
12.7 50.8 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
12.7 12.7 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
12.7 88.6 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
12.6 50.5 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
12.6 37.7 GO:1901421 positive regulation of response to alcohol(GO:1901421)
12.6 75.3 GO:0015680 intracellular copper ion transport(GO:0015680)
12.5 12.5 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
12.5 24.9 GO:0072665 protein localization to vacuole(GO:0072665)
12.5 49.8 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
12.4 99.4 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
12.4 111.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
12.4 494.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
12.3 221.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
12.3 86.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
12.3 196.9 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
12.3 86.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
12.2 36.5 GO:0097086 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
12.2 340.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
12.1 48.6 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
12.1 242.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
12.1 12.1 GO:0097694 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
12.1 133.0 GO:0015939 pantothenate metabolic process(GO:0015939)
12.1 60.3 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
12.1 84.4 GO:0060844 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
12.0 24.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
12.0 108.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
12.0 36.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
12.0 12.0 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
12.0 36.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
12.0 47.8 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
11.9 35.8 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
11.9 47.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
11.9 47.5 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
11.8 189.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
11.8 23.7 GO:0006740 NADPH regeneration(GO:0006740)
11.8 35.5 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
11.7 387.6 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
11.7 654.4 GO:0045454 cell redox homeostasis(GO:0045454)
11.6 104.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
11.5 46.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
11.5 34.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
11.5 23.0 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
11.5 34.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
11.5 45.9 GO:0072683 T cell extravasation(GO:0072683)
11.5 11.5 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
11.4 11.4 GO:1901856 negative regulation of cellular respiration(GO:1901856)
11.4 34.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
11.4 102.5 GO:0000710 meiotic mismatch repair(GO:0000710)
11.3 22.6 GO:0046075 dTTP metabolic process(GO:0046075)
11.3 67.5 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
11.2 55.9 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
11.1 55.7 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
11.1 89.1 GO:0016129 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
11.1 132.9 GO:0006089 lactate metabolic process(GO:0006089)
11.1 442.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
11.0 11.0 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
10.9 21.9 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
10.9 76.5 GO:0015866 ADP transport(GO:0015866)
10.9 76.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
10.8 54.0 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
10.7 32.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
10.7 74.8 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
10.7 96.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
10.7 32.0 GO:1902415 regulation of mRNA binding(GO:1902415)
10.6 31.8 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
10.5 231.7 GO:0051639 actin filament network formation(GO:0051639)
10.5 31.5 GO:0061445 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
10.5 41.9 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
10.5 73.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
10.5 10.5 GO:0060382 regulation of DNA strand elongation(GO:0060382)
10.4 135.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
10.3 82.7 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
10.3 93.0 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
10.3 20.7 GO:0034501 protein localization to kinetochore(GO:0034501)
10.3 1298.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
10.3 10.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
10.3 30.8 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
10.3 102.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
10.3 41.1 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
10.3 30.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
10.2 30.7 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
10.2 30.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
10.2 10.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
10.2 30.5 GO:0036363 transforming growth factor beta activation(GO:0036363)
10.1 20.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
10.1 231.6 GO:0043968 histone H2A acetylation(GO:0043968)
10.0 170.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
10.0 30.1 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
10.0 40.1 GO:0032600 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
10.0 50.0 GO:0080009 mRNA methylation(GO:0080009)
10.0 20.0 GO:0048478 replication fork protection(GO:0048478)
10.0 19.9 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
9.9 139.2 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
9.9 49.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
9.9 218.6 GO:0050872 white fat cell differentiation(GO:0050872)
9.9 39.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
9.9 79.3 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
9.9 39.6 GO:0042262 DNA protection(GO:0042262)
9.9 39.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
9.9 78.8 GO:0007144 female meiosis I(GO:0007144)
9.8 245.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
9.8 29.4 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
9.8 9.8 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
9.8 97.9 GO:0046689 response to mercury ion(GO:0046689)
9.8 48.9 GO:0061441 renal artery morphogenesis(GO:0061441)
9.7 117.0 GO:0001522 pseudouridine synthesis(GO:0001522)
9.7 87.7 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
9.7 48.6 GO:0070269 pyroptosis(GO:0070269)
9.7 19.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
9.7 155.3 GO:0006596 polyamine biosynthetic process(GO:0006596)
9.7 281.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
9.7 58.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
9.6 86.7 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
9.6 76.9 GO:0009249 protein lipoylation(GO:0009249)
9.6 57.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
9.6 57.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
9.6 66.9 GO:0043615 astrocyte cell migration(GO:0043615)
9.5 95.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
9.5 57.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
9.5 47.6 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
9.5 76.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
9.5 9.5 GO:0060066 oviduct development(GO:0060066)
9.5 47.4 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
9.5 18.9 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
9.4 47.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
9.4 141.4 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
9.4 46.9 GO:0016074 snoRNA metabolic process(GO:0016074) snoRNA processing(GO:0043144)
9.4 37.5 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
9.4 84.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
9.4 131.2 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
9.4 37.5 GO:1902463 protein localization to cell leading edge(GO:1902463)
9.3 46.7 GO:1901163 trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163)
9.3 37.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
9.3 27.9 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
9.3 27.9 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
9.2 212.0 GO:0061157 mRNA destabilization(GO:0061157)
9.2 36.9 GO:1902570 protein localization to nucleolus(GO:1902570)
9.2 18.4 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
9.2 119.4 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
9.2 18.3 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
9.1 36.5 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
9.1 9.1 GO:0071306 cellular response to vitamin E(GO:0071306)
9.1 18.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
9.1 81.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
9.1 54.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
9.0 9.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
9.0 18.1 GO:0016584 nucleosome positioning(GO:0016584)
9.0 108.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
9.0 116.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
9.0 143.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
9.0 251.1 GO:0031581 hemidesmosome assembly(GO:0031581)
9.0 53.8 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
9.0 71.7 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
9.0 44.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
8.9 62.6 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
8.9 26.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
8.9 98.1 GO:0090344 negative regulation of cell aging(GO:0090344)
8.9 26.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
8.8 35.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
8.8 203.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
8.8 8.8 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
8.8 35.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
8.8 35.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
8.8 17.5 GO:0048102 autophagic cell death(GO:0048102)
8.7 43.7 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
8.7 26.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
8.7 26.0 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
8.6 34.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
8.6 25.9 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
8.6 25.9 GO:0070625 zymogen granule exocytosis(GO:0070625)
8.6 17.2 GO:1903722 regulation of centriole elongation(GO:1903722)
8.6 77.6 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
8.6 68.8 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
8.5 34.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
8.5 93.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
8.5 93.0 GO:0051096 positive regulation of helicase activity(GO:0051096)
8.4 84.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
8.4 33.7 GO:0003409 optic cup structural organization(GO:0003409)
8.4 84.3 GO:0040016 embryonic cleavage(GO:0040016)
8.4 67.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
8.4 67.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
8.4 25.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
8.4 33.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
8.3 41.7 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
8.3 16.6 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
8.3 8.3 GO:0034398 telomere tethering at nuclear periphery(GO:0034398)
8.3 24.8 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
8.2 33.0 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
8.2 74.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
8.2 41.0 GO:0090168 Golgi reassembly(GO:0090168)
8.2 24.5 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
8.2 73.5 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
8.1 24.4 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
8.1 16.3 GO:0002001 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
8.1 8.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
8.1 96.8 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
8.1 104.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
8.1 40.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
8.0 88.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
8.0 24.0 GO:0061635 regulation of protein complex stability(GO:0061635)
8.0 95.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
8.0 31.8 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
7.9 23.6 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
7.8 133.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
7.8 23.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
7.8 31.2 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
7.8 31.1 GO:0050917 sensory perception of umami taste(GO:0050917)
7.7 23.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
7.7 46.0 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
7.6 53.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
7.6 22.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
7.6 22.8 GO:0048382 mesendoderm development(GO:0048382)
7.5 120.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
7.5 45.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
7.5 157.4 GO:0006465 signal peptide processing(GO:0006465)
7.5 15.0 GO:0003162 atrioventricular node development(GO:0003162)
7.5 67.4 GO:0045116 protein neddylation(GO:0045116)
7.5 104.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
7.5 104.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
7.4 22.3 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
7.4 7.4 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
7.4 37.0 GO:0051382 kinetochore assembly(GO:0051382)
7.4 22.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
7.4 14.8 GO:0070384 Harderian gland development(GO:0070384)
7.4 95.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
7.3 22.0 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
7.3 29.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
7.3 43.8 GO:1904814 regulation of protein localization to chromosome, telomeric region(GO:1904814)
7.3 124.0 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
7.3 14.6 GO:0005997 xylulose metabolic process(GO:0005997)
7.3 65.4 GO:0038203 TORC2 signaling(GO:0038203)
7.2 7.2 GO:0035754 B cell chemotaxis(GO:0035754)
7.2 21.7 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
7.2 28.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
7.2 36.1 GO:0051547 regulation of keratinocyte migration(GO:0051547)
7.2 36.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
7.2 21.5 GO:1904528 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
7.2 71.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
7.2 42.9 GO:0031017 exocrine pancreas development(GO:0031017)
7.1 21.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
7.1 28.6 GO:0002084 protein depalmitoylation(GO:0002084)
7.1 128.3 GO:0002183 cytoplasmic translational initiation(GO:0002183)
7.1 28.5 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
7.1 42.6 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
7.1 120.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
7.1 169.3 GO:0016578 histone deubiquitination(GO:0016578)
7.0 42.3 GO:0007296 vitellogenesis(GO:0007296)
7.0 21.0 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
7.0 14.0 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
7.0 62.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
7.0 48.9 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
7.0 41.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
6.9 27.6 GO:0001302 replicative cell aging(GO:0001302)
6.9 13.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
6.9 75.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
6.9 41.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
6.9 82.7 GO:0070986 left/right axis specification(GO:0070986)
6.9 41.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
6.9 20.6 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
6.9 27.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
6.9 96.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
6.9 27.4 GO:0045218 zonula adherens maintenance(GO:0045218)
6.8 6.8 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
6.8 27.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
6.8 67.5 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566)
6.7 113.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
6.7 13.3 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
6.7 26.7 GO:0009956 radial pattern formation(GO:0009956)
6.7 20.0 GO:0036233 glycine import(GO:0036233)
6.6 19.9 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
6.6 79.6 GO:0017121 phospholipid scrambling(GO:0017121)
6.6 19.9 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
6.6 26.4 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
6.6 13.1 GO:1904796 regulation of core promoter binding(GO:1904796)
6.6 13.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
6.5 32.6 GO:0031053 primary miRNA processing(GO:0031053)
6.5 13.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
6.5 19.5 GO:0034982 protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
6.5 26.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
6.5 19.4 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
6.4 83.7 GO:0035459 cargo loading into vesicle(GO:0035459)
6.4 38.6 GO:0060356 leucine import(GO:0060356)
6.4 25.7 GO:0043555 regulation of translation in response to stress(GO:0043555)
6.4 32.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
6.4 70.7 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
6.4 25.7 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
6.4 32.1 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
6.4 12.8 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
6.4 6.4 GO:0042256 mature ribosome assembly(GO:0042256)
6.4 12.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
6.3 12.7 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
6.3 57.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
6.3 12.6 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
6.3 6.3 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
6.3 50.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
6.3 31.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
6.3 431.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
6.2 12.5 GO:0051182 coenzyme transport(GO:0051182)
6.2 397.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
6.2 12.3 GO:0015917 aminophospholipid transport(GO:0015917)
6.2 80.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
6.1 73.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
6.1 79.9 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
6.1 24.5 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
6.1 42.8 GO:0000012 single strand break repair(GO:0000012)
6.1 36.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
6.1 42.7 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
6.1 42.7 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
6.1 54.7 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
6.1 36.4 GO:0015677 copper ion import(GO:0015677)
6.1 78.8 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
6.0 42.3 GO:0001866 NK T cell proliferation(GO:0001866)
6.0 42.2 GO:0051014 actin filament severing(GO:0051014)
6.0 18.0 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
6.0 131.8 GO:0035456 response to interferon-beta(GO:0035456)
6.0 12.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
6.0 17.9 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
6.0 119.2 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
6.0 29.8 GO:0043418 homocysteine catabolic process(GO:0043418)
6.0 29.8 GO:0033277 abortive mitotic cell cycle(GO:0033277)
5.9 94.9 GO:0032486 Rap protein signal transduction(GO:0032486)
5.9 171.6 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
5.9 142.0 GO:0051031 tRNA transport(GO:0051031)
5.9 41.2 GO:0042407 cristae formation(GO:0042407)
5.9 5.9 GO:0003415 chondrocyte hypertrophy(GO:0003415)
5.9 23.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
5.9 5.9 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
5.8 5.8 GO:0001832 blastocyst growth(GO:0001832)
5.8 35.0 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
5.8 52.5 GO:0089700 protein kinase D signaling(GO:0089700)
5.8 11.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
5.8 23.3 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
5.8 5.8 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
5.7 23.0 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
5.7 17.2 GO:0016240 autophagosome docking(GO:0016240)
5.7 11.4 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
5.7 40.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
5.7 57.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
5.7 22.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
5.7 5.7 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
5.7 22.8 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
5.7 45.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
5.7 51.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
5.7 11.3 GO:0033591 response to L-ascorbic acid(GO:0033591)
5.7 33.9 GO:0061197 fungiform papilla morphogenesis(GO:0061197)
5.6 5.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
5.6 78.9 GO:0001765 membrane raft assembly(GO:0001765)
5.6 371.6 GO:0090114 COPII-coated vesicle budding(GO:0090114)
5.6 5.6 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
5.6 44.8 GO:0051451 myoblast migration(GO:0051451)
5.6 39.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
5.6 33.5 GO:0006415 translational termination(GO:0006415)
5.6 44.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
5.6 38.9 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
5.6 5.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
5.5 11.1 GO:0002317 plasma cell differentiation(GO:0002317)
5.5 27.6 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
5.5 5.5 GO:0044827 modulation by host of viral genome replication(GO:0044827)
5.5 76.9 GO:0070208 protein heterotrimerization(GO:0070208)
5.5 5.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
5.5 10.9 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
5.5 5.5 GO:0051255 spindle midzone assembly(GO:0051255)
5.4 27.2 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
5.4 54.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
5.4 59.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
5.4 48.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
5.4 16.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
5.3 234.6 GO:0043488 regulation of mRNA stability(GO:0043488)
5.3 16.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
5.3 15.9 GO:2000035 regulation of stem cell division(GO:2000035)
5.3 15.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
5.2 15.6 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
5.2 5.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
5.2 36.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
5.2 25.9 GO:1904424 regulation of GTP binding(GO:1904424)
5.2 10.3 GO:1904732 regulation of electron carrier activity(GO:1904732)
5.2 31.0 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
5.2 113.5 GO:0050686 negative regulation of mRNA processing(GO:0050686)
5.1 30.8 GO:0070200 establishment of protein localization to telomere(GO:0070200)
5.1 10.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
5.1 5.1 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
5.1 15.3 GO:0060352 cell adhesion molecule production(GO:0060352)
5.1 15.3 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
5.1 25.4 GO:0032506 cytokinetic process(GO:0032506)
5.1 10.1 GO:0003350 pulmonary myocardium development(GO:0003350)
5.1 10.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
5.0 120.2 GO:0006301 postreplication repair(GO:0006301)
5.0 269.9 GO:0070671 response to interleukin-12(GO:0070671)
5.0 99.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
5.0 39.9 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
5.0 19.9 GO:2000253 positive regulation of feeding behavior(GO:2000253)
4.9 19.8 GO:0070933 histone H4 deacetylation(GO:0070933)
4.9 14.8 GO:0006903 vesicle targeting(GO:0006903)
4.9 14.8 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
4.9 103.4 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
4.9 39.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
4.9 9.8 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
4.9 19.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
4.9 24.3 GO:1903232 melanosome assembly(GO:1903232)
4.8 14.5 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
4.8 57.9 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
4.8 19.3 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
4.8 53.0 GO:0060056 mammary gland involution(GO:0060056)
4.8 4.8 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
4.8 206.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
4.8 14.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
4.7 47.5 GO:0009414 response to water deprivation(GO:0009414)
4.7 19.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
4.7 14.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
4.7 28.2 GO:0044351 macropinocytosis(GO:0044351)
4.7 28.2 GO:0006771 riboflavin metabolic process(GO:0006771)
4.7 173.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
4.6 9.3 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
4.6 27.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
4.6 18.5 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
4.6 9.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
4.6 13.8 GO:0035733 hepatic stellate cell activation(GO:0035733)
4.6 9.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
4.6 13.7 GO:0002934 desmosome organization(GO:0002934)
4.6 9.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
4.6 18.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
4.5 13.6 GO:0032776 DNA methylation on cytosine(GO:0032776)
4.5 22.7 GO:0043457 regulation of cellular respiration(GO:0043457)
4.5 13.6 GO:0072205 metanephric collecting duct development(GO:0072205)
4.5 4.5 GO:0051983 regulation of chromosome segregation(GO:0051983)
4.5 9.0 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
4.5 40.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
4.5 22.4 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
4.5 31.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
4.5 40.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
4.5 17.9 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
4.5 17.9 GO:2000210 positive regulation of anoikis(GO:2000210)
4.5 4.5 GO:0010041 response to iron(III) ion(GO:0010041)
4.5 142.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
4.5 4.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
4.5 17.8 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
4.5 17.8 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
4.4 13.3 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
4.4 4.4 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
4.4 13.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
4.4 17.6 GO:0007386 compartment pattern specification(GO:0007386)
4.4 17.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
4.4 13.1 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
4.4 17.5 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
4.3 4.3 GO:0043366 beta selection(GO:0043366)
4.3 43.5 GO:0048853 forebrain morphogenesis(GO:0048853)
4.3 17.3 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
4.3 25.9 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
4.3 47.3 GO:0060546 negative regulation of necroptotic process(GO:0060546)
4.3 60.0 GO:0050873 brown fat cell differentiation(GO:0050873)
4.3 42.7 GO:0099515 actin filament-based transport(GO:0099515)
4.3 8.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
4.3 217.0 GO:0031124 mRNA 3'-end processing(GO:0031124)
4.2 12.7 GO:0042255 ribosome assembly(GO:0042255)
4.2 8.5 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
4.2 4.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
4.2 89.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
4.2 50.8 GO:0070327 thyroid hormone transport(GO:0070327)
4.2 8.5 GO:0072321 chaperone-mediated protein transport(GO:0072321)
4.2 16.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
4.2 236.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
4.2 25.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
4.2 21.1 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
4.2 4.2 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
4.1 16.6 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
4.1 62.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
4.1 12.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
4.1 8.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
4.1 4.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
4.1 12.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
4.1 73.6 GO:0006270 DNA replication initiation(GO:0006270)
4.1 93.7 GO:0006517 protein deglycosylation(GO:0006517)
4.1 40.7 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
4.1 4.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
4.1 60.8 GO:0051231 spindle elongation(GO:0051231)
4.1 4.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
4.0 68.8 GO:0043388 positive regulation of DNA binding(GO:0043388)
4.0 24.3 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
4.0 28.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
4.0 24.1 GO:0097284 hepatocyte apoptotic process(GO:0097284)
4.0 36.0 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
4.0 11.9 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
4.0 67.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
4.0 71.4 GO:0051642 centrosome localization(GO:0051642)
4.0 19.8 GO:0006574 valine catabolic process(GO:0006574)
4.0 4.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
3.9 19.7 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
3.9 11.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.9 31.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
3.9 3.9 GO:0048295 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) positive regulation of isotype switching to IgE isotypes(GO:0048295)
3.9 19.5 GO:0019050 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
3.9 19.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
3.8 19.2 GO:0007619 courtship behavior(GO:0007619)
3.8 7.7 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
3.8 15.3 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
3.8 15.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
3.8 3.8 GO:0070914 UV-damage excision repair(GO:0070914)
3.8 34.2 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
3.8 3.8 GO:0035574 histone H4-K20 demethylation(GO:0035574)
3.8 18.9 GO:0000733 DNA strand renaturation(GO:0000733)
3.8 30.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
3.8 41.3 GO:0072673 lamellipodium morphogenesis(GO:0072673)
3.8 11.3 GO:0006741 NADP biosynthetic process(GO:0006741)
3.7 86.2 GO:0009649 entrainment of circadian clock(GO:0009649)
3.7 15.0 GO:0043382 regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382)
3.7 26.2 GO:0007379 segment specification(GO:0007379)
3.7 18.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
3.7 37.4 GO:0032905 transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914)
3.7 15.0 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
3.7 48.3 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
3.7 66.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
3.7 58.9 GO:0006353 DNA-templated transcription, termination(GO:0006353)
3.7 18.4 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
3.6 29.1 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
3.6 10.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
3.6 25.4 GO:0046449 creatinine metabolic process(GO:0046449)
3.6 39.9 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
3.6 7.2 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
3.6 57.7 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
3.6 7.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
3.6 3.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
3.6 50.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
3.6 39.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
3.6 7.1 GO:0040031 snRNA modification(GO:0040031)
3.6 17.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
3.6 17.8 GO:0001878 response to yeast(GO:0001878)
3.6 24.9 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
3.5 7.1 GO:0031291 Ran protein signal transduction(GO:0031291)
3.5 70.8 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
3.5 3.5 GO:0007028 cytoplasm organization(GO:0007028)
3.5 102.2 GO:0032392 DNA geometric change(GO:0032392)
3.5 6.9 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
3.5 62.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
3.5 6.9 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
3.5 3.5 GO:0060268 negative regulation of respiratory burst(GO:0060268)
3.4 24.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
3.4 17.2 GO:0035897 proteolysis in other organism(GO:0035897)
3.4 65.3 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
3.4 181.5 GO:0006334 nucleosome assembly(GO:0006334)
3.4 3.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
3.4 30.8 GO:0045793 positive regulation of cell size(GO:0045793)
3.4 3.4 GO:0010455 positive regulation of cell fate commitment(GO:0010455)
3.4 51.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
3.4 10.2 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
3.4 33.8 GO:0045191 regulation of isotype switching(GO:0045191)
3.4 3.4 GO:0019858 cytosine metabolic process(GO:0019858)
3.4 3.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
3.4 67.2 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
3.4 23.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
3.3 23.4 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
3.3 20.1 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
3.3 6.7 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
3.3 23.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
3.3 23.3 GO:0071332 cellular response to fructose stimulus(GO:0071332)
3.3 126.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
3.3 36.6 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
3.3 36.3 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
3.3 29.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
3.3 9.8 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
3.2 9.7 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
3.2 9.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
3.2 9.7 GO:0097264 self proteolysis(GO:0097264)
3.2 22.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
3.2 25.6 GO:0071455 cellular response to hyperoxia(GO:0071455)
3.2 19.2 GO:0006983 ER overload response(GO:0006983)
3.2 9.6 GO:0006642 triglyceride mobilization(GO:0006642)
3.2 63.6 GO:0006754 ATP biosynthetic process(GO:0006754)
3.2 15.9 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
3.2 28.6 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
3.2 6.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
3.2 3.2 GO:0061009 common bile duct development(GO:0061009)
3.2 22.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
3.1 81.4 GO:0007520 myoblast fusion(GO:0007520)
3.1 37.5 GO:0046040 IMP metabolic process(GO:0046040)
3.1 15.6 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
3.1 96.4 GO:0048745 smooth muscle tissue development(GO:0048745)
3.1 15.5 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
3.1 74.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
3.1 24.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
3.1 6.2 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
3.1 48.9 GO:0031648 protein destabilization(GO:0031648)
3.1 88.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
3.1 3.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
3.0 21.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
3.0 15.2 GO:0070383 DNA cytosine deamination(GO:0070383)
3.0 3.0 GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
3.0 87.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
3.0 21.2 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
3.0 6.1 GO:0010225 response to UV-C(GO:0010225)
3.0 12.1 GO:0019348 dolichol metabolic process(GO:0019348)
3.0 27.2 GO:0014854 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870)
3.0 3.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
3.0 90.3 GO:1902402 signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
3.0 12.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
3.0 45.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
3.0 86.3 GO:0090383 phagosome acidification(GO:0090383)
3.0 8.9 GO:0048819 catagen(GO:0042637) positive regulation of hair follicle maturation(GO:0048818) regulation of hair follicle maturation(GO:0048819) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795)
3.0 32.6 GO:0043101 purine-containing compound salvage(GO:0043101)
3.0 11.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
3.0 8.9 GO:0051683 establishment of Golgi localization(GO:0051683)
3.0 17.7 GO:0002418 immune response to tumor cell(GO:0002418)
2.9 5.9 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
2.9 52.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
2.9 73.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
2.9 14.5 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
2.9 86.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
2.9 2.9 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
2.9 8.6 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
2.8 5.7 GO:0072008 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071)
2.8 19.8 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
2.8 36.6 GO:0016180 snRNA processing(GO:0016180)
2.8 16.8 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
2.8 41.9 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
2.8 8.3 GO:0003064 regulation of heart rate by hormone(GO:0003064)
2.8 24.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
2.8 16.5 GO:0042026 protein refolding(GO:0042026)
2.8 104.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
2.8 16.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
2.7 19.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.7 76.5 GO:0035329 hippo signaling(GO:0035329)
2.7 2.7 GO:0090273 positive regulation of pancreatic juice secretion(GO:0090187) regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
2.7 8.1 GO:0001845 phagolysosome assembly(GO:0001845)
2.7 10.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
2.7 8.0 GO:0045324 late endosome to vacuole transport(GO:0045324)
2.7 34.8 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
2.7 26.7 GO:0033622 integrin activation(GO:0033622)
2.6 26.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
2.6 39.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
2.6 55.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
2.6 20.8 GO:0016139 glycoside catabolic process(GO:0016139)
2.6 13.0 GO:0001887 selenium compound metabolic process(GO:0001887)
2.5 27.9 GO:0043983 histone H4-K12 acetylation(GO:0043983)
2.5 397.9 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
2.5 95.5 GO:0045214 sarcomere organization(GO:0045214)
2.5 12.5 GO:1904355 positive regulation of telomere capping(GO:1904355)
2.5 5.0 GO:0007518 myoblast fate determination(GO:0007518)
2.5 12.3 GO:0033028 myeloid cell apoptotic process(GO:0033028)
2.5 110.8 GO:0007062 sister chromatid cohesion(GO:0007062)
2.4 39.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
2.4 26.9 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
2.4 2.4 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
2.4 121.1 GO:0006364 rRNA processing(GO:0006364)
2.4 64.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
2.4 9.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
2.4 38.2 GO:0006101 citrate metabolic process(GO:0006101)
2.4 21.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
2.4 7.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
2.4 2.4 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
2.4 7.1 GO:0002086 diaphragm contraction(GO:0002086)
2.4 2.4 GO:0060374 mast cell differentiation(GO:0060374)
2.4 4.7 GO:0035989 tendon development(GO:0035989)
2.4 7.1 GO:0035811 negative regulation of urine volume(GO:0035811)
2.3 39.9 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
2.3 46.7 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
2.3 23.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
2.3 6.9 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
2.3 2.3 GO:0055093 response to hyperoxia(GO:0055093)
2.3 36.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
2.3 6.8 GO:1901656 glycoside transport(GO:1901656)
2.3 9.0 GO:0007097 nuclear migration(GO:0007097)
2.2 27.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396)
2.2 24.6 GO:0006552 leucine metabolic process(GO:0006551) leucine catabolic process(GO:0006552)
2.2 8.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
2.2 26.5 GO:0006527 arginine catabolic process(GO:0006527)
2.2 13.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
2.2 19.8 GO:1902033 regulation of hematopoietic stem cell proliferation(GO:1902033)
2.2 2.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
2.2 120.5 GO:0006401 RNA catabolic process(GO:0006401)
2.2 8.7 GO:0003150 muscular septum morphogenesis(GO:0003150)
2.2 13.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
2.2 19.6 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
2.2 4.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
2.2 10.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
2.2 13.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
2.1 4.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
2.1 21.4 GO:0040023 establishment of nucleus localization(GO:0040023)
2.1 12.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
2.1 8.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
2.1 87.7 GO:0006413 translational initiation(GO:0006413)
2.1 10.4 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
2.1 10.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
2.1 80.5 GO:0006414 translational elongation(GO:0006414)
2.1 51.5 GO:0008210 estrogen metabolic process(GO:0008210)
2.1 14.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.0 69.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
2.0 6.1 GO:0002818 intracellular defense response(GO:0002818)
2.0 6.0 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
2.0 12.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
2.0 2.0 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.0 2.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
2.0 6.0 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
2.0 10.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
2.0 21.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
2.0 5.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
2.0 3.9 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
2.0 82.2 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
1.9 5.8 GO:0061042 vascular wound healing(GO:0061042)
1.9 3.8 GO:0048535 lymph node development(GO:0048535)
1.9 5.7 GO:0052501 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
1.9 9.6 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
1.9 1.9 GO:0060166 olfactory pit development(GO:0060166)
1.9 3.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.9 1.9 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
1.9 1.9 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
1.9 7.4 GO:0051697 protein delipidation(GO:0051697)
1.8 11.1 GO:0060033 anatomical structure regression(GO:0060033)
1.8 3.6 GO:0031034 myosin filament assembly(GO:0031034)
1.8 7.3 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
1.8 12.6 GO:0071763 nuclear membrane organization(GO:0071763)
1.8 25.2 GO:0051923 sulfation(GO:0051923)
1.8 24.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.8 28.0 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
1.7 3.5 GO:0036018 cellular response to erythropoietin(GO:0036018)
1.7 5.2 GO:0009648 photoperiodism(GO:0009648)
1.7 3.4 GO:0060434 bronchus morphogenesis(GO:0060434)
1.7 5.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
1.7 18.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
1.7 1.7 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
1.7 1.7 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
1.6 8.0 GO:0015692 lead ion transport(GO:0015692)
1.6 14.4 GO:0034465 response to carbon monoxide(GO:0034465)
1.6 4.8 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
1.6 12.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.6 22.2 GO:0031639 plasminogen activation(GO:0031639)
1.6 17.4 GO:0048251 elastic fiber assembly(GO:0048251)
1.6 11.0 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.6 4.7 GO:1902358 sulfate transmembrane transport(GO:1902358)
1.5 4.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
1.5 19.9 GO:0090161 Golgi ribbon formation(GO:0090161)
1.5 41.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
1.5 4.6 GO:0021569 rhombomere 3 development(GO:0021569)
1.5 6.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.5 4.6 GO:0061724 lipophagy(GO:0061724)
1.5 9.1 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.5 15.1 GO:0046688 response to copper ion(GO:0046688)
1.5 1.5 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
1.5 4.5 GO:0000212 meiotic spindle organization(GO:0000212)
1.5 16.4 GO:0042455 ribonucleoside biosynthetic process(GO:0042455)
1.5 1.5 GO:0031268 pseudopodium organization(GO:0031268)
1.5 8.8 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
1.5 2.9 GO:0034378 chylomicron assembly(GO:0034378)
1.4 4.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
1.4 4.3 GO:0006543 glutamine catabolic process(GO:0006543)
1.4 57.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
1.4 1.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
1.4 18.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
1.4 15.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
1.4 33.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
1.4 13.8 GO:0051601 exocyst localization(GO:0051601)
1.4 2.7 GO:0009650 UV protection(GO:0009650)
1.4 6.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
1.4 8.2 GO:0008218 bioluminescence(GO:0008218)
1.4 27.2 GO:0034198 cellular response to amino acid starvation(GO:0034198)
1.4 12.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
1.3 22.8 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
1.3 12.0 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
1.3 19.5 GO:0035987 endodermal cell differentiation(GO:0035987)
1.3 13.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
1.3 6.5 GO:0016554 cytidine to uridine editing(GO:0016554)
1.3 1.3 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
1.3 1.3 GO:0032425 regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
1.2 1.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
1.2 11.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.2 3.7 GO:0051775 response to redox state(GO:0051775)
1.2 14.8 GO:0001709 cell fate determination(GO:0001709)
1.2 7.4 GO:0002155 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
1.2 3.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
1.2 16.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
1.2 1.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
1.2 33.6 GO:0061462 protein localization to lysosome(GO:0061462)
1.2 9.6 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
1.2 8.4 GO:0009651 response to salt stress(GO:0009651)
1.2 3.6 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
1.2 9.4 GO:0071397 cellular response to cholesterol(GO:0071397)
1.2 4.7 GO:0010643 cell communication by chemical coupling(GO:0010643)
1.2 1.2 GO:0097320 membrane tubulation(GO:0097320)
1.2 20.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
1.2 10.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
1.1 12.4 GO:0006739 NADP metabolic process(GO:0006739)
1.1 5.6 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.1 5.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
1.1 7.7 GO:0042401 cellular biogenic amine biosynthetic process(GO:0042401)
1.1 1.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
1.1 9.8 GO:0060416 response to growth hormone(GO:0060416)
1.1 3.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.1 5.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
1.1 11.7 GO:1903321 negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
1.1 7.4 GO:0030091 protein repair(GO:0030091)
1.0 2.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.0 5.2 GO:1903027 regulation of opsonization(GO:1903027)
1.0 4.2 GO:0071361 cellular response to ethanol(GO:0071361)
1.0 6.1 GO:0090103 cochlea morphogenesis(GO:0090103)
1.0 2.0 GO:0042659 regulation of cell fate specification(GO:0042659)
1.0 22.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
1.0 4.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
1.0 6.0 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
1.0 3.9 GO:0031507 heterochromatin assembly(GO:0031507)
1.0 1.0 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
1.0 5.9 GO:0009437 carnitine metabolic process(GO:0009437)
1.0 1.9 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
1.0 39.7 GO:0043171 peptide catabolic process(GO:0043171)
1.0 1.0 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.9 2.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.9 2.8 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.9 9.3 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.9 12.9 GO:0003334 keratinocyte development(GO:0003334)
0.9 8.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.9 2.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.9 10.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.9 13.2 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.9 6.2 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.9 2.6 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.8 6.7 GO:0007031 peroxisome organization(GO:0007031)
0.8 2.5 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.8 0.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.8 1.6 GO:0035425 autocrine signaling(GO:0035425)
0.8 4.9 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.8 2.4 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.8 4.6 GO:0032472 Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472)
0.8 9.2 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.8 3.0 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.8 23.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.7 0.7 GO:0070295 renal water absorption(GO:0070295)
0.7 9.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.7 2.2 GO:0045794 negative regulation of cell volume(GO:0045794)
0.7 8.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.7 3.6 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.7 1.4 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.7 7.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.7 0.7 GO:0002436 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.7 2.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.7 14.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.7 45.3 GO:0016126 sterol biosynthetic process(GO:0016126)
0.7 0.7 GO:0060157 urinary bladder development(GO:0060157)
0.7 0.7 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.7 4.7 GO:0003096 renal sodium ion transport(GO:0003096)
0.7 2.7 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.6 1.3 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.6 3.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.6 1.9 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.6 3.1 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.6 3.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.6 1.2 GO:0021764 amygdala development(GO:0021764)
0.6 12.5 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.6 1.8 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.6 1.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.6 1.2 GO:0003164 His-Purkinje system development(GO:0003164)
0.6 1.2 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.6 11.9 GO:0031529 ruffle organization(GO:0031529)
0.6 7.7 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.6 2.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.5 12.1 GO:0015893 drug transport(GO:0015893)
0.5 6.5 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.5 0.5 GO:0007343 egg activation(GO:0007343)
0.5 3.8 GO:0046348 amino sugar catabolic process(GO:0046348)
0.5 0.5 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.5 6.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.5 3.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.5 2.1 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.5 2.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.5 5.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.5 1.5 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.5 5.1 GO:0015732 prostaglandin transport(GO:0015732)
0.5 2.5 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.5 16.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.5 1.0 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
0.5 1.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.5 3.4 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.5 1.5 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.5 10.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.5 4.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.5 2.4 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.5 1.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4 0.4 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.4 6.0 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 5.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.4 1.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.4 5.4 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.4 5.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.4 1.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 7.9 GO:0006611 protein export from nucleus(GO:0006611)
0.4 14.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 1.9 GO:1903299 regulation of hexokinase activity(GO:1903299)
0.4 0.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.4 20.4 GO:0002377 immunoglobulin production(GO:0002377)
0.3 1.0 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.3 1.0 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.3 1.7 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 2.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.3 0.3 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.3 5.0 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.3 0.6 GO:0015884 folic acid transport(GO:0015884)
0.3 1.8 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.3 0.9 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.3 6.7 GO:0046031 ADP metabolic process(GO:0046031)
0.3 1.4 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.3 85.1 GO:0042119 neutrophil activation(GO:0042119)
0.3 1.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 1.0 GO:0009404 toxin metabolic process(GO:0009404)
0.3 1.3 GO:0033227 dsRNA transport(GO:0033227)
0.2 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 0.7 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 2.7 GO:0002076 osteoblast development(GO:0002076)
0.2 0.4 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.2 11.4 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.2 2.5 GO:0042100 B cell proliferation(GO:0042100)
0.2 1.0 GO:0043616 keratinocyte proliferation(GO:0043616)
0.2 0.4 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.2 0.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.1 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.2 15.1 GO:0070268 cornification(GO:0070268)
0.2 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 1.2 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.8 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.3 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.1 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.1 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.2 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.0 0.7 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.0 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.0 0.6 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032434)
0.0 0.0 GO:0070242 thymocyte apoptotic process(GO:0070242)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.0 GO:0097152 mesenchymal cell apoptotic process(GO:0097152) regulation of mesenchymal cell apoptotic process(GO:2001053)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
63.5 254.0 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
50.0 200.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
45.8 229.0 GO:0031523 Myb complex(GO:0031523)
44.7 134.0 GO:0036284 tubulobulbar complex(GO:0036284)
43.4 130.2 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
36.3 435.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
34.2 171.0 GO:0042643 actomyosin, actin portion(GO:0042643)
32.5 195.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
32.0 352.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
30.9 277.7 GO:0005787 signal peptidase complex(GO:0005787)
29.7 89.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
29.3 146.5 GO:0097149 centralspindlin complex(GO:0097149)
28.6 142.8 GO:0005683 U7 snRNP(GO:0005683)
28.2 112.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
27.3 218.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
26.5 265.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
26.5 79.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
26.4 105.6 GO:0071159 NF-kappaB complex(GO:0071159)
26.4 237.2 GO:0000125 PCAF complex(GO:0000125)
25.9 77.6 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
25.9 25.9 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
25.2 75.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
25.0 200.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
24.4 390.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
24.0 143.7 GO:0009368 endopeptidase Clp complex(GO:0009368)
23.2 162.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
22.9 114.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
22.8 274.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
22.8 250.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
22.8 91.1 GO:0071942 XPC complex(GO:0071942)
22.7 136.0 GO:0097422 tubular endosome(GO:0097422)
22.5 157.7 GO:1990111 spermatoproteasome complex(GO:1990111)
22.1 154.4 GO:0016589 NURF complex(GO:0016589)
22.0 88.2 GO:1990246 uniplex complex(GO:1990246)
21.9 306.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
21.3 85.3 GO:0071817 MMXD complex(GO:0071817)
20.8 62.4 GO:1990038 glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
20.8 187.1 GO:0072546 ER membrane protein complex(GO:0072546)
20.7 413.9 GO:0005838 proteasome regulatory particle(GO:0005838)
20.5 82.2 GO:0000811 GINS complex(GO:0000811)
20.3 264.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
20.1 260.9 GO:0005688 U6 snRNP(GO:0005688)
19.8 138.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
19.8 98.8 GO:0033503 HULC complex(GO:0033503)
19.8 98.8 GO:0070557 PCNA-p21 complex(GO:0070557)
19.4 38.9 GO:1990730 VCP-NSFL1C complex(GO:1990730)
19.4 19.4 GO:0097454 Schwann cell microvillus(GO:0097454)
19.2 76.9 GO:0022624 proteasome accessory complex(GO:0022624)
19.0 94.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
18.6 111.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
18.5 73.9 GO:0071986 Ragulator complex(GO:0071986)
18.4 92.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
18.3 183.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
18.2 73.0 GO:0005846 nuclear cap binding complex(GO:0005846)
17.9 143.5 GO:0000796 condensin complex(GO:0000796)
17.8 35.5 GO:0001651 dense fibrillar component(GO:0001651)
17.6 87.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
17.0 51.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
16.9 50.6 GO:0018444 translation release factor complex(GO:0018444)
16.5 66.2 GO:0071920 cleavage body(GO:0071920)
16.5 49.5 GO:0043259 laminin-10 complex(GO:0043259)
16.4 16.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
16.3 48.8 GO:0044393 microspike(GO:0044393)
16.1 451.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
16.1 128.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
15.8 79.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
15.8 110.8 GO:0016272 prefoldin complex(GO:0016272)
15.7 188.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
15.7 31.5 GO:1990023 mitotic spindle midzone(GO:1990023)
15.7 31.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
15.6 140.4 GO:0042382 paraspeckles(GO:0042382)
15.6 202.6 GO:0042555 MCM complex(GO:0042555)
15.5 62.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
15.3 168.1 GO:0042612 MHC class I protein complex(GO:0042612)
15.3 45.8 GO:0030689 Noc complex(GO:0030689)
15.2 182.8 GO:0008290 F-actin capping protein complex(GO:0008290)
15.0 90.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
15.0 45.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
15.0 30.0 GO:0031262 Ndc80 complex(GO:0031262)
14.8 14.8 GO:0005687 U4 snRNP(GO:0005687)
14.6 161.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
14.6 145.9 GO:0097255 R2TP complex(GO:0097255)
14.5 406.6 GO:0005680 anaphase-promoting complex(GO:0005680)
14.5 144.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
14.5 86.9 GO:0031298 replication fork protection complex(GO:0031298)
14.5 231.6 GO:0031080 nuclear pore outer ring(GO:0031080)
14.5 563.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
14.3 57.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
14.1 126.9 GO:0090543 Flemming body(GO:0090543)
14.0 126.3 GO:0032133 chromosome passenger complex(GO:0032133)
13.8 41.3 GO:0033565 ESCRT-0 complex(GO:0033565)
13.5 135.5 GO:0034709 methylosome(GO:0034709)
13.3 173.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
13.1 183.6 GO:0070938 contractile ring(GO:0070938)
13.1 52.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
13.1 65.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
13.0 182.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
13.0 221.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
13.0 103.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
12.8 64.2 GO:0032301 MutSalpha complex(GO:0032301)
12.8 217.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
12.7 25.4 GO:0035061 interchromatin granule(GO:0035061)
12.5 50.1 GO:0005960 glycine cleavage complex(GO:0005960)
12.3 197.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
12.2 36.7 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
12.2 97.9 GO:0031616 spindle pole centrosome(GO:0031616)
12.2 73.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
12.0 601.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
12.0 48.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
12.0 96.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
12.0 251.7 GO:0032433 filopodium tip(GO:0032433)
12.0 47.9 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
11.9 59.3 GO:0005839 proteasome core complex(GO:0005839)
11.9 11.9 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
11.8 58.9 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
11.7 210.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
11.6 127.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
11.6 254.6 GO:0000502 proteasome complex(GO:0000502)
11.5 34.6 GO:0043159 acrosomal matrix(GO:0043159)
11.5 69.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
11.4 57.0 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
11.3 79.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
11.2 56.2 GO:0005663 DNA replication factor C complex(GO:0005663)
11.2 56.1 GO:0032449 CBM complex(GO:0032449)
11.1 178.3 GO:0070578 RISC-loading complex(GO:0070578)
11.1 77.8 GO:0031415 NatA complex(GO:0031415)
11.1 88.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
11.0 99.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
10.9 120.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
10.8 227.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
10.8 32.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
10.8 21.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
10.7 42.7 GO:0030905 retromer, tubulation complex(GO:0030905)
10.7 42.7 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
10.6 42.4 GO:0005715 late recombination nodule(GO:0005715)
10.5 42.1 GO:1990357 terminal web(GO:1990357)
10.5 1124.3 GO:0015934 large ribosomal subunit(GO:0015934)
10.5 31.5 GO:0035370 UBC13-UEV1A complex(GO:0035370)
10.2 81.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
10.2 91.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
10.2 142.4 GO:0005686 U2 snRNP(GO:0005686)
10.2 30.5 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
10.1 50.7 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
10.1 80.8 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
10.1 171.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
10.1 10.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
10.0 180.6 GO:0030014 CCR4-NOT complex(GO:0030014)
10.0 59.8 GO:0061617 MICOS complex(GO:0061617)
9.9 49.5 GO:0001939 female pronucleus(GO:0001939)
9.9 19.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
9.8 294.3 GO:0031143 pseudopodium(GO:0031143)
9.8 1114.4 GO:0035578 azurophil granule lumen(GO:0035578)
9.7 87.3 GO:0044754 autolysosome(GO:0044754)
9.7 48.4 GO:0089701 U2AF(GO:0089701)
9.6 48.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
9.5 47.6 GO:0043564 Ku70:Ku80 complex(GO:0043564)
9.5 47.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
9.5 28.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
9.3 9.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
9.3 120.3 GO:0016600 flotillin complex(GO:0016600)
9.1 36.3 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
9.0 63.2 GO:0044530 supraspliceosomal complex(GO:0044530)
9.0 9.0 GO:0097342 ripoptosome(GO:0097342)
9.0 53.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
8.9 53.6 GO:0005610 laminin-5 complex(GO:0005610)
8.9 79.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
8.9 150.5 GO:0030127 COPII vesicle coat(GO:0030127)
8.8 17.7 GO:0005845 mRNA cap binding complex(GO:0005845)
8.7 78.1 GO:0070531 BRCA1-A complex(GO:0070531)
8.4 1206.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
8.3 16.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
8.3 108.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
8.3 41.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
8.3 58.0 GO:0032021 NELF complex(GO:0032021)
8.0 48.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
8.0 79.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
7.9 268.7 GO:0071564 npBAF complex(GO:0071564)
7.8 156.5 GO:0005684 U2-type spliceosomal complex(GO:0005684)
7.8 23.4 GO:1990393 3M complex(GO:1990393)
7.8 93.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
7.7 54.1 GO:0030677 ribonuclease P complex(GO:0030677)
7.7 177.7 GO:0005844 polysome(GO:0005844)
7.7 23.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
7.7 92.0 GO:0090544 BAF-type complex(GO:0090544)
7.7 61.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
7.6 38.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
7.6 160.1 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
7.6 22.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
7.6 121.7 GO:0042405 nuclear inclusion body(GO:0042405)
7.5 67.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
7.5 497.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
7.5 30.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
7.5 1088.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
7.5 59.9 GO:0051286 cell tip(GO:0051286)
7.4 51.6 GO:0001520 outer dense fiber(GO:0001520)
7.4 80.9 GO:0005638 lamin filament(GO:0005638)
7.3 36.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
7.3 65.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
7.2 72.3 GO:0032059 bleb(GO:0032059)
7.2 50.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
7.2 64.4 GO:0036449 microtubule minus-end(GO:0036449)
7.1 591.1 GO:0005643 nuclear pore(GO:0005643)
7.1 21.2 GO:0005588 collagen type V trimer(GO:0005588)
7.0 1149.8 GO:0005681 spliceosomal complex(GO:0005681)
7.0 612.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
6.9 206.8 GO:0016469 proton-transporting two-sector ATPase complex(GO:0016469)
6.9 220.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
6.8 61.3 GO:0001673 male germ cell nucleus(GO:0001673)
6.7 13.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
6.7 379.7 GO:0005876 spindle microtubule(GO:0005876)
6.7 99.8 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
6.7 133.1 GO:0070822 Sin3-type complex(GO:0070822)
6.6 32.8 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
6.6 72.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
6.4 12.9 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
6.2 31.2 GO:0000178 exosome (RNase complex)(GO:0000178)
6.2 130.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
6.1 18.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
6.1 48.8 GO:0070652 HAUS complex(GO:0070652)
6.0 54.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
6.0 24.2 GO:0044307 dendritic branch(GO:0044307)
6.0 24.2 GO:0048179 activin receptor complex(GO:0048179)
6.0 65.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
6.0 411.0 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
5.9 17.8 GO:0000798 nuclear cohesin complex(GO:0000798)
5.8 29.2 GO:0032044 DSIF complex(GO:0032044)
5.8 23.3 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
5.8 34.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
5.8 23.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
5.8 34.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
5.8 63.3 GO:0044666 MLL3/4 complex(GO:0044666)
5.7 310.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
5.7 51.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
5.6 158.1 GO:0000421 autophagosome membrane(GO:0000421)
5.6 242.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
5.6 73.2 GO:0005662 DNA replication factor A complex(GO:0005662)
5.6 44.7 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
5.6 83.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
5.5 71.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
5.5 55.1 GO:0097443 sorting endosome(GO:0097443)
5.5 43.9 GO:0071203 WASH complex(GO:0071203)
5.5 137.0 GO:0031264 death-inducing signaling complex(GO:0031264)
5.5 87.3 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
5.4 38.1 GO:0097413 Lewy body(GO:0097413)
5.4 16.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
5.4 118.5 GO:0030056 hemidesmosome(GO:0030056)
5.4 171.6 GO:0000776 kinetochore(GO:0000776)
5.4 16.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
5.3 31.7 GO:0005916 fascia adherens(GO:0005916)
5.3 100.1 GO:0035861 site of double-strand break(GO:0035861)
5.3 63.0 GO:0030008 TRAPP complex(GO:0030008)
5.2 5.2 GO:0035189 Rb-E2F complex(GO:0035189)
5.2 219.3 GO:0035577 azurophil granule membrane(GO:0035577)
5.2 5.2 GO:0032807 DNA ligase IV complex(GO:0032807)
5.2 177.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
5.1 20.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
5.1 301.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
5.1 5.1 GO:0005899 insulin receptor complex(GO:0005899)
4.9 44.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
4.9 2299.9 GO:0005925 focal adhesion(GO:0005925)
4.9 19.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
4.8 14.4 GO:1902636 kinociliary basal body(GO:1902636)
4.8 38.4 GO:0031209 SCAR complex(GO:0031209)
4.8 19.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
4.7 250.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
4.7 18.9 GO:0005675 holo TFIIH complex(GO:0005675) carboxy-terminal domain protein kinase complex(GO:0032806)
4.6 27.9 GO:0010369 chromocenter(GO:0010369)
4.6 41.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
4.6 83.1 GO:0005640 nuclear outer membrane(GO:0005640)
4.6 13.8 GO:0035517 PR-DUB complex(GO:0035517)
4.6 68.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
4.5 9.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
4.4 65.7 GO:0001891 phagocytic cup(GO:0001891)
4.4 61.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
4.3 21.7 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
4.3 12.9 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
4.3 51.4 GO:0000815 ESCRT III complex(GO:0000815)
4.2 4.2 GO:1990075 periciliary membrane compartment(GO:1990075)
4.2 25.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
4.2 29.6 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
4.2 33.5 GO:0005587 collagen type IV trimer(GO:0005587)
4.2 8.3 GO:0070939 Dsl1p complex(GO:0070939)
4.2 29.2 GO:0030686 90S preribosome(GO:0030686)
4.2 83.3 GO:0005719 nuclear euchromatin(GO:0005719)
4.2 16.6 GO:0046581 intercellular canaliculus(GO:0046581)
4.1 12.4 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
4.1 36.8 GO:0070449 elongin complex(GO:0070449)
4.1 32.6 GO:0016011 dystroglycan complex(GO:0016011)
4.0 12.1 GO:0030312 external encapsulating structure(GO:0030312)
4.0 19.9 GO:0070765 gamma-secretase complex(GO:0070765)
4.0 11.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
3.9 7.8 GO:0070761 pre-snoRNP complex(GO:0070761)
3.9 42.7 GO:0032039 integrator complex(GO:0032039)
3.9 42.5 GO:0097470 ribbon synapse(GO:0097470)
3.9 23.1 GO:0071797 LUBAC complex(GO:0071797)
3.8 30.4 GO:0005915 zonula adherens(GO:0005915)
3.8 105.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
3.8 41.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
3.7 26.0 GO:0030904 retromer complex(GO:0030904)
3.7 602.3 GO:0031968 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
3.7 11.1 GO:0034457 Mpp10 complex(GO:0034457)
3.7 11.0 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
3.7 22.1 GO:0032389 MutLalpha complex(GO:0032389)
3.7 3.7 GO:0043260 laminin-11 complex(GO:0043260)
3.6 219.0 GO:0000793 condensed chromosome(GO:0000793)
3.6 3.6 GO:0034518 RNA cap binding complex(GO:0034518)
3.6 25.0 GO:0000124 SAGA complex(GO:0000124)
3.6 21.3 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
3.5 109.3 GO:0008180 COP9 signalosome(GO:0008180)
3.4 58.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
3.4 164.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
3.4 23.8 GO:0001741 XY body(GO:0001741)
3.4 233.3 GO:0005913 cell-cell adherens junction(GO:0005913)
3.3 33.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
3.3 16.4 GO:1990425 ryanodine receptor complex(GO:1990425)
3.1 9.4 GO:0070876 SOSS complex(GO:0070876)
3.0 15.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
3.0 116.6 GO:0005840 ribosome(GO:0005840)
3.0 74.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
3.0 29.6 GO:0002102 podosome(GO:0002102)
2.9 58.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
2.9 34.7 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
2.8 234.8 GO:0070821 tertiary granule membrane(GO:0070821)
2.8 2.8 GO:0000805 X chromosome(GO:0000805)
2.8 16.5 GO:0031088 platelet dense granule membrane(GO:0031088)
2.7 35.3 GO:0030125 clathrin vesicle coat(GO:0030125)
2.7 78.5 GO:0005637 nuclear inner membrane(GO:0005637)
2.7 18.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.6 21.0 GO:0061689 tricellular tight junction(GO:0061689)
2.6 28.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
2.6 7.8 GO:0005873 plus-end kinesin complex(GO:0005873)
2.6 79.4 GO:0032420 stereocilium(GO:0032420)
2.5 55.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
2.5 7.5 GO:0070195 growth hormone receptor complex(GO:0070195)
2.5 2.5 GO:0005797 Golgi medial cisterna(GO:0005797)
2.5 495.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
2.4 16.6 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
2.4 52.1 GO:0030992 intraciliary transport particle B(GO:0030992)
2.4 7.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
2.4 40.2 GO:0031528 microvillus membrane(GO:0031528)
2.3 41.4 GO:0031089 platelet dense granule lumen(GO:0031089)
2.3 34.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
2.2 15.4 GO:0070187 telosome(GO:0070187)
2.2 2.2 GO:0005606 laminin-1 complex(GO:0005606)
2.1 23.5 GO:0017119 Golgi transport complex(GO:0017119)
2.1 59.9 GO:0005902 microvillus(GO:0005902)
2.1 19.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
2.1 19.1 GO:0044194 cytolytic granule(GO:0044194)
2.1 24.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
2.0 22.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
2.0 81.1 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
2.0 2.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
2.0 21.9 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
2.0 55.7 GO:0005605 basal lamina(GO:0005605)
2.0 7.9 GO:0033263 CORVET complex(GO:0033263)
2.0 141.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
2.0 3.9 GO:0033186 CAF-1 complex(GO:0033186)
1.9 1.9 GO:1990462 omegasome(GO:1990462)
1.9 9.7 GO:0001739 sex chromatin(GO:0001739)
1.9 15.4 GO:1990909 Wnt signalosome(GO:1990909)
1.9 5.7 GO:0097452 GAIT complex(GO:0097452)
1.9 15.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.9 11.3 GO:0032279 asymmetric synapse(GO:0032279)
1.9 5.6 GO:0036021 endolysosome lumen(GO:0036021)
1.9 3.8 GO:0070435 Shc-EGFR complex(GO:0070435)
1.9 22.4 GO:0030684 preribosome(GO:0030684)
1.8 18.4 GO:0008385 IkappaB kinase complex(GO:0008385)
1.8 12.7 GO:0030478 actin cap(GO:0030478)
1.8 1.8 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
1.8 34.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.8 9.0 GO:0034719 SMN-Sm protein complex(GO:0034719)
1.8 123.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
1.8 82.9 GO:0035580 specific granule lumen(GO:0035580)
1.8 7.0 GO:0033553 rDNA heterochromatin(GO:0033553)
1.8 15.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.7 5.2 GO:0002081 outer acrosomal membrane(GO:0002081)
1.7 3.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.7 1.7 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
1.7 69.0 GO:0035579 specific granule membrane(GO:0035579)
1.6 51.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.6 6.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.6 266.7 GO:0005819 spindle(GO:0005819)
1.6 11.0 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
1.5 6.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.5 1079.6 GO:0005730 nucleolus(GO:0005730)
1.5 3.0 GO:0055087 Ski complex(GO:0055087)
1.4 51.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
1.4 2.8 GO:0005740 mitochondrial envelope(GO:0005740)
1.4 49.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
1.4 51.3 GO:0045095 keratin filament(GO:0045095)
1.3 5.3 GO:0031010 ISWI-type complex(GO:0031010)
1.3 73.8 GO:0031966 mitochondrial membrane(GO:0031966)
1.3 121.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
1.2 293.8 GO:0005759 mitochondrial matrix(GO:0005759)
1.2 15.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
1.2 8.5 GO:0097449 astrocyte projection(GO:0097449)
1.2 3.5 GO:0005592 collagen type XI trimer(GO:0005592)
1.1 4.5 GO:0042581 specific granule(GO:0042581)
1.1 4.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
1.1 122.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
1.1 2.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
1.1 1.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
1.1 5.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.1 2.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.1 6.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
1.1 15.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.0 69.6 GO:0017053 transcriptional repressor complex(GO:0017053)
1.0 3.9 GO:0005677 chromatin silencing complex(GO:0005677)
1.0 1.9 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.9 3.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.8 1823.3 GO:0070062 extracellular exosome(GO:0070062)
0.8 7.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.8 3.1 GO:0043196 varicosity(GO:0043196)
0.7 18.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.7 0.7 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.7 1.4 GO:0031970 organelle envelope lumen(GO:0031970)
0.7 2.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.6 1.9 GO:0097486 multivesicular body lumen(GO:0097486)
0.6 3.0 GO:1902560 GMP reductase complex(GO:1902560)
0.6 4.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.6 2.9 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.5 2.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.5 2.4 GO:0043291 RAVE complex(GO:0043291)
0.5 9.0 GO:0032432 actin filament bundle(GO:0032432)
0.5 11.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 16.3 GO:0005811 lipid particle(GO:0005811)
0.3 2.3 GO:0061574 ASAP complex(GO:0061574)
0.3 4.1 GO:0032982 myosin filament(GO:0032982)
0.3 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 16.4 GO:0016605 PML body(GO:0016605)
0.2 15.5 GO:0032993 protein-DNA complex(GO:0032993)
0.2 41.4 GO:0005635 nuclear envelope(GO:0005635)
0.1 1.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 0.5 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
63.5 254.0 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
56.4 225.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
50.0 200.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
47.7 143.1 GO:0098808 mRNA cap binding(GO:0098808)
42.3 169.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
41.3 123.9 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
39.0 116.9 GO:0004170 dUTP diphosphatase activity(GO:0004170)
39.0 116.9 GO:0009041 uridylate kinase activity(GO:0009041)
37.7 188.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
36.7 183.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
36.0 108.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
35.2 105.6 GO:0004132 dCMP deaminase activity(GO:0004132)
34.9 104.8 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
34.6 173.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
32.6 97.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
30.8 184.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
30.4 121.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
30.3 91.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
30.3 90.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
30.1 210.6 GO:0061133 endopeptidase activator activity(GO:0061133)
29.7 89.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
27.6 82.7 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
27.4 82.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
27.3 218.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
26.8 107.2 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
26.7 133.6 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
25.9 77.6 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
25.9 155.1 GO:0004849 uridine kinase activity(GO:0004849)
25.7 154.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
25.6 205.0 GO:0015288 porin activity(GO:0015288)
25.4 76.1 GO:0005046 KDEL sequence binding(GO:0005046)
24.7 98.8 GO:0033897 ribonuclease T2 activity(GO:0033897)
24.5 440.8 GO:0001055 RNA polymerase II activity(GO:0001055)
24.4 121.9 GO:0004774 succinate-CoA ligase activity(GO:0004774)
23.8 71.5 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
23.3 651.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
23.0 161.0 GO:0032217 riboflavin transporter activity(GO:0032217)
22.9 45.8 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
22.9 137.2 GO:0019238 cyclohydrolase activity(GO:0019238)
22.7 250.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
22.5 67.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
22.2 199.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
22.0 88.1 GO:0002060 purine nucleobase binding(GO:0002060)
21.9 219.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
21.9 109.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
21.8 87.4 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
21.8 130.7 GO:0046979 TAP2 binding(GO:0046979)
21.8 87.1 GO:0003883 CTP synthase activity(GO:0003883)
21.5 85.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
21.4 214.0 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
21.4 64.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
21.1 147.5 GO:0005497 androgen binding(GO:0005497)
20.9 104.6 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
20.5 61.4 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
20.4 122.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
20.3 81.3 GO:0043515 kinetochore binding(GO:0043515)
20.1 80.2 GO:0033677 DNA/RNA helicase activity(GO:0033677)
20.0 20.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
20.0 280.1 GO:0031386 protein tag(GO:0031386)
20.0 60.0 GO:0032767 copper-dependent protein binding(GO:0032767)
19.8 138.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
19.7 118.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
19.6 78.3 GO:0004001 adenosine kinase activity(GO:0004001)
19.5 78.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
19.5 58.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
19.5 58.5 GO:0004998 transferrin receptor activity(GO:0004998)
19.3 135.0 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
19.2 76.8 GO:0071987 WD40-repeat domain binding(GO:0071987)
19.0 228.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
18.9 75.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
18.8 56.5 GO:0004566 beta-glucuronidase activity(GO:0004566)
18.8 56.3 GO:0004766 spermidine synthase activity(GO:0004766)
18.7 168.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
18.4 128.7 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
18.3 54.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
18.3 109.6 GO:0097100 supercoiled DNA binding(GO:0097100)
17.8 71.4 GO:0004074 biliverdin reductase activity(GO:0004074)
17.8 71.3 GO:0016418 S-acetyltransferase activity(GO:0016418)
17.8 17.8 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
17.8 53.3 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
17.2 120.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
17.0 50.9 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
16.9 388.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
16.9 50.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
16.7 50.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
16.6 778.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
16.5 214.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
16.5 98.8 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
16.4 114.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
16.4 65.5 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
16.4 180.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
16.3 97.7 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
16.2 48.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
16.2 96.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
16.1 80.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
15.9 79.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
15.9 79.6 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
15.9 63.5 GO:0098770 FBXO family protein binding(GO:0098770)
15.8 15.8 GO:0031177 phosphopantetheine binding(GO:0031177)
15.7 47.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
15.7 141.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
15.6 62.2 GO:1990254 keratin filament binding(GO:1990254)
15.5 46.5 GO:0004056 argininosuccinate lyase activity(GO:0004056)
15.5 139.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
15.5 46.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
15.4 15.4 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
15.4 15.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
15.4 370.2 GO:0070628 proteasome binding(GO:0070628)
15.3 91.7 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
15.2 90.9 GO:0004594 pantothenate kinase activity(GO:0004594)
15.0 90.2 GO:0005047 signal recognition particle binding(GO:0005047)
15.0 135.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
14.9 59.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
14.8 148.4 GO:0033592 RNA strand annealing activity(GO:0033592)
14.8 44.3 GO:0001069 regulatory region RNA binding(GO:0001069)
14.8 59.0 GO:0016530 metallochaperone activity(GO:0016530)
14.7 59.0 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
14.6 117.0 GO:0050733 RS domain binding(GO:0050733)
14.6 43.8 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
14.5 58.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
14.5 101.6 GO:0070990 snRNP binding(GO:0070990)
14.4 115.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
14.1 14.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
14.1 254.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
14.1 84.4 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
14.0 27.9 GO:0043398 HLH domain binding(GO:0043398)
13.9 55.5 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
13.8 83.1 GO:0070513 death domain binding(GO:0070513)
13.8 55.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
13.7 82.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
13.7 178.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
13.6 40.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
13.5 135.3 GO:0070883 pre-miRNA binding(GO:0070883)
13.5 54.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
13.5 40.4 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
13.4 40.2 GO:0031403 lithium ion binding(GO:0031403)
13.3 80.0 GO:0030620 U2 snRNA binding(GO:0030620)
13.3 53.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
13.2 39.6 GO:0070336 flap-structured DNA binding(GO:0070336)
13.2 171.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
13.1 65.7 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
13.1 418.8 GO:0008143 poly(A) binding(GO:0008143)
13.0 51.9 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
12.9 141.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
12.8 64.2 GO:0032143 single thymine insertion binding(GO:0032143)
12.8 64.2 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
12.8 102.3 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
12.6 37.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
12.6 37.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
12.5 37.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
12.5 224.3 GO:0017070 U6 snRNA binding(GO:0017070)
12.4 99.1 GO:0042301 phosphate ion binding(GO:0042301)
12.3 12.3 GO:0032810 sterol response element binding(GO:0032810)
12.1 72.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
12.1 84.4 GO:0000150 recombinase activity(GO:0000150)
12.0 72.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
12.0 60.0 GO:1990460 leptin receptor binding(GO:1990460)
11.9 119.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
11.9 35.7 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
11.9 106.8 GO:1990226 histone methyltransferase binding(GO:1990226)
11.9 308.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
11.8 35.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
11.8 35.4 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
11.7 70.5 GO:0016748 succinyltransferase activity(GO:0016748)
11.7 35.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
11.7 35.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
11.6 23.2 GO:0070717 poly-purine tract binding(GO:0070717)
11.6 23.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
11.5 34.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
11.5 34.5 GO:0055100 adiponectin binding(GO:0055100)
11.5 34.5 GO:0000104 succinate dehydrogenase activity(GO:0000104)
11.5 275.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
11.5 34.4 GO:0003896 DNA primase activity(GO:0003896)
11.4 216.9 GO:0043495 protein anchor(GO:0043495)
11.4 34.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
11.3 34.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
11.3 22.6 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
11.3 33.8 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
11.3 33.8 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
11.2 22.3 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
11.1 55.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
11.0 44.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
11.0 55.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
11.0 2257.4 GO:0003735 structural constituent of ribosome(GO:0003735)
10.9 76.5 GO:0015217 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
10.9 65.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
10.9 21.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
10.8 64.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
10.8 172.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
10.7 32.0 GO:0031626 beta-endorphin binding(GO:0031626)
10.6 127.7 GO:0016004 phospholipase activator activity(GO:0016004)
10.6 42.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
10.5 210.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
10.5 305.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
10.5 31.5 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
10.5 41.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
10.5 41.9 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
10.4 31.1 GO:0051920 peroxiredoxin activity(GO:0051920)
10.4 124.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
10.3 41.3 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
10.3 113.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
10.3 30.8 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
10.3 71.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
10.3 82.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
10.2 61.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
10.2 30.7 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
10.1 40.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
10.1 30.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
10.1 30.2 GO:0036219 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
10.0 60.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
10.0 260.0 GO:0070182 DNA polymerase binding(GO:0070182)
9.9 297.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
9.8 29.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
9.7 29.1 GO:0008097 5S rRNA binding(GO:0008097)
9.7 48.5 GO:0035173 histone kinase activity(GO:0035173)
9.7 9.7 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
9.6 77.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
9.6 38.4 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
9.6 28.7 GO:0004638 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
9.5 66.7 GO:0001849 complement component C1q binding(GO:0001849)
9.4 18.9 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
9.4 358.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
9.4 103.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
9.4 18.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
9.3 9.3 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
9.3 93.1 GO:0070878 primary miRNA binding(GO:0070878)
9.3 55.8 GO:0036033 mediator complex binding(GO:0036033)
9.3 27.9 GO:0043035 chromatin insulator sequence binding(GO:0043035)
9.3 9.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
9.3 55.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
9.3 92.6 GO:0000339 RNA cap binding(GO:0000339)
9.2 351.1 GO:0031369 translation initiation factor binding(GO:0031369)
9.2 64.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
9.2 45.8 GO:0035613 RNA stem-loop binding(GO:0035613)
9.1 72.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
9.1 117.9 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
9.1 18.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
9.0 27.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
9.0 99.0 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
9.0 26.9 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
8.9 232.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
8.8 61.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
8.8 8.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
8.8 96.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
8.7 26.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
8.7 113.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
8.7 43.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
8.6 25.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
8.6 34.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
8.4 236.4 GO:0017166 vinculin binding(GO:0017166)
8.4 25.2 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
8.4 42.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
8.4 41.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
8.4 58.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
8.3 25.0 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
8.3 91.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
8.3 33.3 GO:0070644 vitamin D response element binding(GO:0070644)
8.3 74.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
8.3 24.8 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
8.2 57.7 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
8.2 24.6 GO:0019826 oxygen sensor activity(GO:0019826)
8.2 16.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
8.1 445.8 GO:0031593 polyubiquitin binding(GO:0031593)
8.1 8.1 GO:0016778 diphosphotransferase activity(GO:0016778)
8.1 24.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
8.0 32.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
8.0 152.0 GO:0051400 BH domain binding(GO:0051400)
8.0 32.0 GO:0004743 pyruvate kinase activity(GO:0004743)
8.0 47.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
8.0 31.8 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
7.9 23.8 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
7.9 47.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
7.9 157.2 GO:0008301 DNA binding, bending(GO:0008301)
7.8 242.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
7.8 77.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
7.8 38.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
7.8 46.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
7.7 107.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
7.7 15.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
7.6 114.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
7.5 158.5 GO:0003746 translation elongation factor activity(GO:0003746)
7.5 60.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
7.5 299.3 GO:0003743 translation initiation factor activity(GO:0003743)
7.5 194.4 GO:0042288 MHC class I protein binding(GO:0042288)
7.5 231.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
7.4 183.8 GO:0051059 NF-kappaB binding(GO:0051059)
7.3 14.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
7.3 219.7 GO:0070410 co-SMAD binding(GO:0070410)
7.3 160.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
7.3 7.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
7.3 29.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
7.3 14.5 GO:0004920 interleukin-10 receptor activity(GO:0004920)
7.3 29.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
7.2 21.7 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
7.2 172.5 GO:0017025 TBP-class protein binding(GO:0017025)
7.2 78.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
7.2 21.5 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
7.1 14.2 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
7.0 14.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
7.0 125.3 GO:0016018 cyclosporin A binding(GO:0016018)
6.9 27.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
6.9 82.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
6.9 41.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
6.9 191.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
6.8 54.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
6.8 47.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
6.8 27.1 GO:0019798 procollagen-proline dioxygenase activity(GO:0019798)
6.7 94.2 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
6.7 40.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
6.7 53.6 GO:0070569 uridylyltransferase activity(GO:0070569)
6.7 201.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
6.7 46.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
6.7 59.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
6.6 59.5 GO:0001222 transcription corepressor binding(GO:0001222)
6.5 77.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
6.4 25.7 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
6.4 44.9 GO:0019534 toxin transporter activity(GO:0019534)
6.4 6.4 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
6.4 44.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
6.3 31.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
6.3 18.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
6.3 37.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
6.3 18.8 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
6.2 31.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
6.2 460.2 GO:0019003 GDP binding(GO:0019003)
6.2 74.6 GO:0003688 DNA replication origin binding(GO:0003688)
6.2 6.2 GO:0070404 NADH binding(GO:0070404)
6.1 72.9 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
6.0 66.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
6.0 6.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
6.0 54.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
6.0 48.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
6.0 96.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
6.0 18.0 GO:0004017 adenylate kinase activity(GO:0004017)
6.0 6.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
6.0 6.0 GO:0042809 vitamin D receptor binding(GO:0042809)
5.9 29.7 GO:0004905 type I interferon receptor activity(GO:0004905)
5.9 35.6 GO:0016842 amidine-lyase activity(GO:0016842)
5.9 23.8 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
5.9 59.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
5.9 53.2 GO:0046790 virion binding(GO:0046790)
5.9 29.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
5.9 105.7 GO:0030515 snoRNA binding(GO:0030515)
5.9 11.7 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
5.8 35.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
5.8 40.7 GO:0050815 phosphoserine binding(GO:0050815)
5.8 34.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
5.8 23.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
5.8 272.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
5.8 23.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
5.8 5.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
5.7 211.2 GO:0043236 laminin binding(GO:0043236)
5.7 34.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
5.7 45.4 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
5.7 56.7 GO:0035877 death effector domain binding(GO:0035877)
5.6 2160.9 GO:0045296 cadherin binding(GO:0045296)
5.6 44.7 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
5.5 11.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
5.5 22.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
5.5 264.8 GO:0050699 WW domain binding(GO:0050699)
5.5 21.9 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
5.5 208.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
5.5 21.9 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
5.5 38.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
5.4 69.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
5.4 16.1 GO:0070704 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
5.4 5.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
5.3 16.0 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
5.3 15.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
5.3 42.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
5.3 26.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
5.3 10.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
5.3 15.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
5.2 25.9 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
5.2 31.0 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
5.2 97.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
5.1 66.8 GO:0016289 CoA hydrolase activity(GO:0016289) acyl-CoA hydrolase activity(GO:0047617)
5.1 20.5 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
5.1 30.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
5.1 46.0 GO:0035174 histone serine kinase activity(GO:0035174)
5.1 5.1 GO:0019239 deaminase activity(GO:0019239)
5.1 30.4 GO:0019237 centromeric DNA binding(GO:0019237)
5.1 202.5 GO:0042169 SH2 domain binding(GO:0042169)
5.0 55.2 GO:0001056 RNA polymerase III activity(GO:0001056)
5.0 24.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
5.0 14.9 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
4.9 14.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
4.9 455.7 GO:0003697 single-stranded DNA binding(GO:0003697)
4.9 136.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
4.8 9.7 GO:0008169 C-methyltransferase activity(GO:0008169)
4.8 33.9 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
4.8 19.3 GO:0004335 galactokinase activity(GO:0004335)
4.8 72.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
4.8 28.8 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
4.8 14.4 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
4.8 4.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
4.7 4.7 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
4.7 205.6 GO:0050681 androgen receptor binding(GO:0050681)
4.7 42.0 GO:0050692 DBD domain binding(GO:0050692)
4.7 4.7 GO:0046923 ER retention sequence binding(GO:0046923)
4.6 46.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
4.6 32.3 GO:0030274 LIM domain binding(GO:0030274)
4.6 9.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
4.6 27.5 GO:1990763 arrestin family protein binding(GO:1990763)
4.6 36.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
4.6 72.9 GO:0097602 cullin family protein binding(GO:0097602)
4.5 131.1 GO:0042605 peptide antigen binding(GO:0042605)
4.5 17.9 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
4.5 31.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
4.4 53.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
4.4 35.3 GO:0070087 chromo shadow domain binding(GO:0070087)
4.4 17.6 GO:0015266 protein channel activity(GO:0015266)
4.4 74.4 GO:0017154 semaphorin receptor activity(GO:0017154)
4.4 13.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
4.4 47.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
4.3 21.7 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
4.3 17.3 GO:0002046 opsin binding(GO:0002046)
4.3 81.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
4.3 29.8 GO:0046527 glucosyltransferase activity(GO:0046527)
4.2 16.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
4.2 59.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
4.2 134.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
4.2 50.4 GO:0017049 GTP-Rho binding(GO:0017049)
4.2 54.1 GO:0043022 ribosome binding(GO:0043022)
4.2 108.1 GO:0001671 ATPase activator activity(GO:0001671)
4.1 49.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
4.0 4.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
4.0 8.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
4.0 28.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
4.0 24.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
4.0 11.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
3.9 19.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
3.9 78.7 GO:0032036 myosin heavy chain binding(GO:0032036)
3.9 366.0 GO:0047485 protein N-terminus binding(GO:0047485)
3.9 15.6 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
3.9 108.7 GO:0019956 chemokine binding(GO:0019956)
3.9 7.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
3.9 11.6 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
3.9 142.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
3.8 107.5 GO:0005123 death receptor binding(GO:0005123)
3.8 34.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
3.8 19.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
3.8 11.4 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
3.8 18.9 GO:0036310 annealing helicase activity(GO:0036310)
3.8 11.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
3.8 71.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
3.7 11.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
3.7 78.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
3.7 144.6 GO:0004407 histone deacetylase activity(GO:0004407)
3.7 29.5 GO:0051525 NFAT protein binding(GO:0051525)
3.7 33.1 GO:0042609 CD4 receptor binding(GO:0042609)
3.7 69.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
3.7 3.7 GO:0032089 NACHT domain binding(GO:0032089)
3.7 25.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
3.6 21.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
3.6 237.0 GO:0008307 structural constituent of muscle(GO:0008307)
3.6 18.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
3.6 90.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
3.6 14.5 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
3.6 97.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
3.6 18.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
3.6 46.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
3.5 7.1 GO:0017089 glycolipid transporter activity(GO:0017089)
3.5 240.3 GO:0008565 protein transporter activity(GO:0008565)
3.5 3.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
3.5 28.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
3.5 14.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
3.5 3.5 GO:0050693 LBD domain binding(GO:0050693)
3.4 20.5 GO:0004000 adenosine deaminase activity(GO:0004000)
3.4 10.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
3.4 27.1 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
3.4 27.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
3.4 3.4 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
3.3 67.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
3.3 10.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
3.3 10.0 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
3.3 16.6 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
3.3 10.0 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
3.3 29.8 GO:0070324 thyroid hormone binding(GO:0070324)
3.3 3.3 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
3.3 29.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
3.3 19.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
3.3 201.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
3.2 9.7 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
3.2 240.0 GO:0051082 unfolded protein binding(GO:0051082)
3.2 67.3 GO:0001221 transcription cofactor binding(GO:0001221)
3.2 6.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
3.2 12.8 GO:0048256 flap endonuclease activity(GO:0048256)
3.2 15.9 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
3.1 83.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
3.1 34.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
3.1 83.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
3.1 9.2 GO:0017018 myosin phosphatase activity(GO:0017018)
3.1 18.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
3.0 30.5 GO:0031014 troponin T binding(GO:0031014)
3.0 45.6 GO:0030547 receptor inhibitor activity(GO:0030547)
3.0 18.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
3.0 9.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
3.0 18.1 GO:0003678 DNA helicase activity(GO:0003678)
3.0 21.1 GO:0000182 rDNA binding(GO:0000182)
3.0 42.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
3.0 27.1 GO:0034452 dynactin binding(GO:0034452)
3.0 15.0 GO:0030348 syntaxin-3 binding(GO:0030348)
3.0 41.9 GO:0030215 semaphorin receptor binding(GO:0030215)
3.0 14.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
2.9 20.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
2.9 26.4 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
2.9 20.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
2.8 31.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
2.8 11.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
2.8 17.0 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
2.8 8.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.8 155.1 GO:0003725 double-stranded RNA binding(GO:0003725)
2.7 120.7 GO:0043130 ubiquitin binding(GO:0043130)
2.7 8.2 GO:0046848 hydroxyapatite binding(GO:0046848)
2.7 16.2 GO:0045545 syndecan binding(GO:0045545)
2.7 10.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
2.7 172.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
2.7 356.3 GO:0005178 integrin binding(GO:0005178)
2.7 31.9 GO:0070034 telomerase RNA binding(GO:0070034)
2.7 15.9 GO:0015057 thrombin receptor activity(GO:0015057)
2.6 108.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
2.6 73.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
2.6 31.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
2.6 10.5 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
2.6 5.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
2.6 7.7 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
2.6 359.3 GO:0051015 actin filament binding(GO:0051015)
2.6 5.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
2.5 170.6 GO:0070888 E-box binding(GO:0070888)
2.5 5.1 GO:0048408 epidermal growth factor binding(GO:0048408)
2.5 74.6 GO:0016831 carboxy-lyase activity(GO:0016831)
2.4 12.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
2.4 53.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
2.4 7.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
2.4 12.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
2.4 7.1 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
2.3 23.5 GO:0001727 lipid kinase activity(GO:0001727)
2.3 16.4 GO:0050542 icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
2.3 4.7 GO:0004530 deoxyribonuclease I activity(GO:0004530)
2.3 6.9 GO:0004914 interleukin-5 receptor activity(GO:0004914)
2.3 20.5 GO:0051879 Hsp90 protein binding(GO:0051879)
2.3 84.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
2.3 2367.7 GO:0003723 RNA binding(GO:0003723)
2.3 6.8 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
2.2 17.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.2 11.1 GO:0019776 Atg8 ligase activity(GO:0019776)
2.2 112.3 GO:0008234 cysteine-type peptidase activity(GO:0008234)
2.2 45.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
2.2 36.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
2.1 4.2 GO:0048039 ubiquinone binding(GO:0048039)
2.1 19.0 GO:0050700 CARD domain binding(GO:0050700)
2.1 4.2 GO:0005131 growth hormone receptor binding(GO:0005131)
2.1 20.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
2.0 8.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
2.0 4.0 GO:0008384 IkappaB kinase activity(GO:0008384)
2.0 6.0 GO:0045182 translation regulator activity(GO:0045182)
2.0 2.0 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
1.9 5.8 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.9 9.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.9 5.7 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
1.9 9.6 GO:0004966 galanin receptor activity(GO:0004966)
1.9 9.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.9 15.2 GO:0015245 fatty acid transporter activity(GO:0015245)
1.9 16.7 GO:0004645 phosphorylase activity(GO:0004645)
1.9 14.8 GO:0015923 mannosidase activity(GO:0015923)
1.8 5.5 GO:0004958 prostaglandin F receptor activity(GO:0004958)
1.8 12.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
1.8 7.4 GO:0047685 amine sulfotransferase activity(GO:0047685)
1.8 76.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.8 10.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.8 3.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
1.8 7.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
1.8 9.0 GO:0000832 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
1.8 16.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.8 7.2 GO:0042608 T cell receptor binding(GO:0042608)
1.8 14.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.7 15.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.7 5.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
1.7 5.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.7 3.4 GO:0004126 cytidine deaminase activity(GO:0004126)
1.7 18.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.7 5.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
1.6 11.5 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
1.6 29.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.6 14.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.6 6.4 GO:0017160 Ral GTPase binding(GO:0017160)
1.6 6.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
1.6 6.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
1.6 1.6 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
1.6 7.8 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.6 3.1 GO:0004104 cholinesterase activity(GO:0004104)
1.6 14.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.6 3.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.5 24.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
1.5 50.6 GO:0005540 hyaluronic acid binding(GO:0005540)
1.5 12.2 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
1.5 10.6 GO:0016403 dimethylargininase activity(GO:0016403)
1.5 22.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.5 1.5 GO:0045550 geranylgeranyl reductase activity(GO:0045550) indanol dehydrogenase activity(GO:0047718)
1.4 5.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.4 20.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
1.4 10.9 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
1.4 9.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.3 2.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
1.3 25.2 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
1.3 19.9 GO:0042974 retinoic acid receptor binding(GO:0042974)
1.3 7.9 GO:0048185 activin binding(GO:0048185)
1.3 5.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.3 10.4 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
1.3 5.1 GO:0061665 SUMO ligase activity(GO:0061665)
1.3 6.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.3 3.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.2 8.7 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
1.2 20.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
1.2 19.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
1.2 2.4 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
1.2 4.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.2 20.0 GO:0003951 NAD+ kinase activity(GO:0003951)
1.2 44.6 GO:0015485 cholesterol binding(GO:0015485)
1.2 15.1 GO:0015926 glucosidase activity(GO:0015926)
1.2 10.4 GO:0035497 cAMP response element binding(GO:0035497)
1.1 2.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.1 8.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.1 3.4 GO:0016790 thiolester hydrolase activity(GO:0016790)
1.1 4.5 GO:0005124 scavenger receptor binding(GO:0005124)
1.1 52.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.1 3.3 GO:0004348 glucosylceramidase activity(GO:0004348)
1.1 2.1 GO:0031692 alpha-1B adrenergic receptor binding(GO:0031692)
1.0 3.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
1.0 75.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
1.0 20.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
1.0 9.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
1.0 3.0 GO:0016936 galactoside binding(GO:0016936)
1.0 1.0 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.0 13.7 GO:0048018 receptor agonist activity(GO:0048018)
1.0 92.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.0 22.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
1.0 9.6 GO:0034062 RNA polymerase activity(GO:0034062)
0.9 7.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.9 1.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.9 319.8 GO:0003712 transcription cofactor activity(GO:0003712)
0.9 4.5 GO:0004771 sterol esterase activity(GO:0004771)
0.9 2.7 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.9 3.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.9 38.4 GO:0035326 enhancer binding(GO:0035326)
0.8 3.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.7 9.6 GO:0031419 cobalamin binding(GO:0031419)
0.7 8.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.7 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.7 42.6 GO:0009055 electron carrier activity(GO:0009055)
0.7 15.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.7 4.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7 12.2 GO:0001848 complement binding(GO:0001848)
0.7 4.0 GO:0098821 BMP receptor activity(GO:0098821)
0.6 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.6 3.1 GO:0097016 L27 domain binding(GO:0097016)
0.6 1.8 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.6 3.0 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.6 3.6 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.6 3.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.6 1.8 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.6 1.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.6 36.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.6 2.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.6 2.3 GO:0032190 acrosin binding(GO:0032190)
0.6 5.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 4.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.6 10.5 GO:0005080 protein kinase C binding(GO:0005080)
0.6 2.8 GO:0008517 folic acid transporter activity(GO:0008517)
0.5 2.2 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.5 2.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.5 35.1 GO:0001618 virus receptor activity(GO:0001618)
0.5 1.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.4 2.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.4 4.7 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.4 11.0 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.4 2.0 GO:0034711 inhibin binding(GO:0034711)
0.4 1.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.4 1.2 GO:0046870 cadmium ion binding(GO:0046870)
0.4 8.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 17.9 GO:0032947 protein complex scaffold(GO:0032947)
0.4 2.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 0.9 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.3 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3 8.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 2.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 27.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.2 17.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 1.8 GO:0005523 tropomyosin binding(GO:0005523)
0.2 2.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.2 1.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0043295 glutathione binding(GO:0043295)
0.1 5.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.1 GO:0005549 odorant binding(GO:0005549)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 1.0 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
21.4 42.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
16.0 31.9 PID IFNG PATHWAY IFN-gamma pathway
14.8 593.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
14.5 203.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
14.3 1945.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
13.7 150.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
10.5 240.4 PID ATR PATHWAY ATR signaling pathway
9.9 257.3 PID FANCONI PATHWAY Fanconi anemia pathway
9.8 459.7 PID BARD1 PATHWAY BARD1 signaling events
9.5 66.5 PID WNT SIGNALING PATHWAY Wnt signaling network
9.3 308.2 PID ATM PATHWAY ATM pathway
9.3 511.4 PID AURORA B PATHWAY Aurora B signaling
9.2 524.5 PID PLK1 PATHWAY PLK1 signaling events
9.2 284.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
9.0 771.1 PID ILK PATHWAY Integrin-linked kinase signaling
8.9 97.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
8.5 347.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
6.9 250.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
6.9 345.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
6.8 136.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
6.8 651.7 PID E2F PATHWAY E2F transcription factor network
6.7 436.3 PID RAC1 PATHWAY RAC1 signaling pathway
6.5 254.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
6.3 31.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
6.1 352.1 PID TELOMERASE PATHWAY Regulation of Telomerase
6.0 6.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
5.8 324.7 PID FOXO PATHWAY FoxO family signaling
5.5 16.4 PID FAS PATHWAY FAS (CD95) signaling pathway
5.4 48.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
5.4 215.5 PID ALK1 PATHWAY ALK1 signaling events
5.3 37.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
5.1 288.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
5.0 206.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
5.0 65.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
4.9 103.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
4.8 47.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
4.7 80.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
4.7 9.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
4.7 485.0 PID AR PATHWAY Coregulation of Androgen receptor activity
4.7 37.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
4.6 114.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
4.5 108.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
4.4 75.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
4.4 87.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
4.3 64.4 PID TRAIL PATHWAY TRAIL signaling pathway
4.3 252.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
4.1 94.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
3.9 3.9 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
3.9 109.4 PID TNF PATHWAY TNF receptor signaling pathway
3.9 15.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
3.7 204.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
3.7 96.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
3.7 118.4 PID IL6 7 PATHWAY IL6-mediated signaling events
3.6 213.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
3.6 93.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
3.4 95.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
3.3 29.6 PID IGF1 PATHWAY IGF1 pathway
3.3 196.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
3.3 13.0 PID EPO PATHWAY EPO signaling pathway
3.2 107.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
3.2 38.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
3.1 27.6 PID CD40 PATHWAY CD40/CD40L signaling
3.0 185.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
3.0 362.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
3.0 21.0 PID IL3 PATHWAY IL3-mediated signaling events
3.0 18.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
3.0 32.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
3.0 20.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
3.0 121.2 PID TGFBR PATHWAY TGF-beta receptor signaling
2.9 83.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
2.8 22.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
2.7 99.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
2.5 5.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
2.1 45.5 PID ARF 3PATHWAY Arf1 pathway
2.0 12.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.9 23.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.9 66.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
1.8 49.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
1.8 29.8 PID IL2 1PATHWAY IL2-mediated signaling events
1.7 25.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
1.7 42.1 PID P53 REGULATION PATHWAY p53 pathway
1.6 80.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
1.6 51.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
1.5 68.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.5 33.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.4 25.1 SIG CHEMOTAXIS Genes related to chemotaxis
1.4 325.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.2 50.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
1.2 4.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
1.2 39.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
1.2 89.0 PID CMYB PATHWAY C-MYB transcription factor network
1.2 7.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
1.1 13.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
1.1 23.3 PID ATF2 PATHWAY ATF-2 transcription factor network
1.0 182.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.0 6.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
1.0 4.1 ST JAK STAT PATHWAY Jak-STAT Pathway
1.0 13.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.9 9.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.9 17.4 PID RHOA PATHWAY RhoA signaling pathway
0.8 29.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.8 10.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.7 35.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.7 8.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.6 27.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.4 5.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.4 12.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.3 5.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 6.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.3 4.7 PID NOTCH PATHWAY Notch signaling pathway
0.2 3.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 4.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
26.2 392.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
25.8 850.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
25.1 25.1 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
24.1 1759.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
23.3 46.7 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
23.1 345.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
22.4 335.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
22.0 505.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
19.7 295.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
19.4 638.9 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
18.1 361.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
17.4 139.6 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
16.5 380.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
15.5 170.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
15.3 152.8 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
14.9 164.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
14.2 170.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
14.2 467.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
14.0 126.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
13.9 13.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
13.9 236.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
13.8 13.8 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
13.5 256.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
13.5 202.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
13.4 53.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
13.4 520.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
13.3 40.0 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
13.2 539.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
13.1 288.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
13.0 764.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
12.8 436.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
12.7 216.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
12.7 936.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
12.6 139.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
12.6 12.6 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
12.4 199.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
12.4 12.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
11.8 1384.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
11.7 411.2 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
11.7 422.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
11.7 70.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
11.5 298.6 REACTOME TRANSLATION Genes involved in Translation
11.3 270.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
11.3 90.1 REACTOME POL SWITCHING Genes involved in Polymerase switching
11.0 241.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
10.7 128.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
10.4 311.0 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
10.2 20.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
10.1 231.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
9.6 181.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
9.5 162.3 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
9.3 428.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
9.0 36.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
9.0 1010.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
9.0 214.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
8.9 186.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
8.9 115.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
8.8 166.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
8.7 69.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
8.5 221.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
8.5 119.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
8.5 323.0 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
8.4 185.0 REACTOME PURINE METABOLISM Genes involved in Purine metabolism
8.4 67.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
8.4 41.9 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
8.2 370.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
8.2 65.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
8.1 97.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
8.1 146.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
8.1 145.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
7.9 79.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
7.9 78.6 REACTOME S PHASE Genes involved in S Phase
7.8 139.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
7.5 734.4 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
7.5 29.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
7.4 297.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
7.4 29.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
7.3 232.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
7.3 617.5 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
6.9 206.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
6.5 32.6 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
6.5 110.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
6.5 309.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
6.3 69.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
6.3 119.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
6.3 12.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
6.3 88.0 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
6.2 493.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
6.2 295.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
5.8 151.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
5.6 371.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
5.5 5.5 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
5.4 48.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
5.1 138.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
5.0 150.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
5.0 95.4 REACTOME PROTEIN FOLDING Genes involved in Protein folding
4.9 163.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
4.9 93.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
4.9 58.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
4.8 116.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
4.8 48.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
4.8 154.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
4.8 67.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
4.8 47.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
4.8 133.6 REACTOME G1 PHASE Genes involved in G1 Phase
4.7 28.2 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
4.6 198.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
4.6 567.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
4.5 36.0 REACTOME MITOTIC G1 G1 S PHASES Genes involved in Mitotic G1-G1/S phases
4.4 198.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
4.4 78.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
4.3 4.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
4.3 630.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
4.2 37.5 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
4.1 24.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
4.1 45.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
4.1 57.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
4.0 4.0 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
3.8 98.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
3.6 46.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
3.5 184.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
3.5 49.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
3.4 126.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
3.4 97.7 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
3.3 76.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
3.3 85.3 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
3.2 64.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
3.1 12.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
3.1 85.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
3.0 24.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
2.9 55.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
2.8 2.8 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
2.8 222.0 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
2.7 10.8 REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT Genes involved in The citric acid (TCA) cycle and respiratory electron transport
2.6 52.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
2.6 75.7 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
2.6 20.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
2.6 26.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
2.6 87.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
2.5 40.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
2.5 12.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
2.4 41.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
2.4 83.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
2.4 33.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
2.3 36.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
2.2 33.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
2.2 19.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
2.2 6.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
2.1 62.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
2.1 60.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
2.1 67.8 REACTOME MEIOSIS Genes involved in Meiosis
2.1 12.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
2.0 17.9 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
2.0 39.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
1.9 15.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
1.9 21.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.8 18.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.8 18.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
1.6 250.2 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
1.6 11.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
1.5 9.3 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
1.5 66.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
1.4 8.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.4 41.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
1.4 15.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
1.4 25.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
1.4 31.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.4 77.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
1.3 54.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
1.3 19.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
1.3 15.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.3 12.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.3 22.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.2 30.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
1.2 136.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
1.2 16.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
1.1 6.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
1.1 7.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
1.1 22.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
1.1 9.6 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
1.1 12.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
1.1 13.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
1.0 35.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
1.0 5.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
1.0 22.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.8 132.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.8 14.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.7 23.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.7 15.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 3.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.6 3.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 1.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.5 20.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.5 1.4 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.4 7.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.4 6.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 8.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 9.5 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.3 7.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.3 2.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.3 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.3 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 3.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 5.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.3 3.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 4.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2 5.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.2 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 1.1 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.1 2.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling