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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZNF784

Z-value: 8.28

Motif logo

Transcription factors associated with ZNF784

Gene Symbol Gene ID Gene Info
ENSG00000179922.6 ZNF784

Activity profile of ZNF784 motif

Sorted Z-values of ZNF784 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF784

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_195583931 36.89 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr11_-_5227063 30.91 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr8_+_79611036 25.33 ENST00000220876.12
ENST00000518111.5
stathmin 2
chr3_-_42264887 24.34 ENST00000334681.9
cholecystokinin
chr4_+_157220654 22.78 ENST00000393815.6
glutamate ionotropic receptor AMPA type subunit 2
chr4_+_157220691 22.26 ENST00000509417.5
ENST00000645636.1
ENST00000296526.12
ENST00000264426.14
glutamate ionotropic receptor AMPA type subunit 2
chr11_+_73647549 22.03 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr11_-_12008584 19.21 ENST00000534511.5
ENST00000683431.1
dickkopf WNT signaling pathway inhibitor 3
chr10_+_80408503 18.65 ENST00000606162.6
peroxiredoxin like 2A
chr3_-_47578832 16.22 ENST00000264723.9
ENST00000610462.1
chondroitin sulfate proteoglycan 5
chr11_-_6419051 16.07 ENST00000299402.10
ENST00000532020.2
ENST00000609360.6
ENST00000389906.6
amyloid beta precursor protein binding family B member 1
chr19_-_41994217 15.81 ENST00000648268.1
ENST00000545399.6
ATPase Na+/K+ transporting subunit alpha 3
chr3_+_50674896 15.72 ENST00000266037.10
dedicator of cytokinesis 3
chr11_-_6419394 15.68 ENST00000311051.7
amyloid beta precursor protein binding family B member 1
chr17_-_10697501 15.43 ENST00000577427.1
ENST00000255390.10
synthesis of cytochrome C oxidase 1
chrX_-_54357993 15.39 ENST00000375169.7
ENST00000354646.6
WNK lysine deficient protein kinase 3
chr19_-_41994079 14.82 ENST00000602133.5
ATPase Na+/K+ transporting subunit alpha 3
chr6_+_150721073 14.64 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr12_-_91178520 13.78 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
decorin
chr15_+_24954912 13.72 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr10_-_91633057 13.56 ENST00000238994.6
protein phosphatase 1 regulatory subunit 3C
chr3_-_9792691 12.39 ENST00000343450.2
transcriptional adaptor 3
chr5_-_150155828 12.30 ENST00000261799.9
platelet derived growth factor receptor beta
chr4_-_89836963 11.88 ENST00000420646.6
ENST00000673718.1
synuclein alpha
chr1_-_17119435 11.50 ENST00000375481.1
ENST00000375486.9
peptidyl arginine deiminase 2
chr9_-_136203183 11.34 ENST00000371746.9
LIM homeobox 3
chr4_-_89837106 11.31 ENST00000394986.5
ENST00000394991.8
ENST00000506244.5
ENST00000394989.6
ENST00000673902.1
ENST00000674129.1
synuclein alpha
chr3_-_39280021 11.23 ENST00000399220.3
C-X3-C motif chemokine receptor 1
chr5_+_161848112 11.14 ENST00000393943.10
gamma-aminobutyric acid type A receptor subunit alpha1
chr16_+_1333631 11.07 ENST00000397488.6
ENST00000562208.5
ENST00000568887.5
ENST00000426824.8
BAI1 associated protein 3
chr10_-_125823089 10.85 ENST00000368774.1
ENST00000368778.7
ENST00000649536.1
uroporphyrinogen III synthase
chr5_-_74767105 10.83 ENST00000509430.5
ENST00000296805.8
ENST00000345239.6
ENST00000427854.6
ENST00000506778.1
GTP dependent ribosome recycling factor mitochondrial 2
chr6_-_149718034 10.72 ENST00000458696.2
ENST00000543571.6
ENST00000392273.7
large tumor suppressor kinase 1
chr2_-_68157470 10.66 ENST00000406245.6
ENST00000409164.1
ENST00000295121.11
WD repeat domain 92
chr3_-_39280432 10.64 ENST00000542107.5
ENST00000435290.1
C-X3-C motif chemokine receptor 1
chr10_+_80408485 9.99 ENST00000615554.4
ENST00000372185.5
peroxiredoxin like 2A
chr19_-_57477503 9.79 ENST00000596831.1
ENST00000601768.1
ENST00000600175.5
ENST00000356584.8
ENST00000425074.3
ENST00000343280.8
ENST00000427512.6
ENST00000615214.3
ENST00000610548.2
novel transcript
zinc finger protein 772
chr12_-_66130702 9.68 ENST00000446587.2
ENST00000266604.7
LLP homolog, long-term synaptic facilitation factor
chr10_-_79445617 9.55 ENST00000372336.4
zinc finger CCHC-type containing 24
chr5_+_137889469 9.48 ENST00000290431.5
polycystin 2 like 2, transient receptor potential cation channel
chr1_+_50109620 9.43 ENST00000371819.1
ELAV like RNA binding protein 4
chr7_-_103989516 9.43 ENST00000343529.9
ENST00000424685.3
reelin
chr3_+_45026296 9.32 ENST00000296130.5
C-type lectin domain family 3 member B
chr4_-_89835617 9.26 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr4_+_70397931 8.88 ENST00000399575.7
opiorphin prepropeptide
chr19_+_49119531 8.81 ENST00000334186.9
PTPRF interacting protein alpha 3
chr2_-_85612023 8.73 ENST00000409734.3
ENST00000306336.6
chromosome 2 open reading frame 68
chr1_+_65792889 8.70 ENST00000341517.9
phosphodiesterase 4B
chr4_-_89836213 8.63 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr10_-_125823221 8.48 ENST00000420761.5
ENST00000368797.10
uroporphyrinogen III synthase
chr1_+_50109817 8.46 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAV like RNA binding protein 4
chr15_+_88803426 8.43 ENST00000560601.4
ENST00000561243.7
ENST00000439576.7
aggrecan
chr18_-_24272179 8.37 ENST00000399443.7
oxysterol binding protein like 1A
chr22_+_20080211 8.32 ENST00000383024.6
ENST00000351989.8
DGCR8 microprocessor complex subunit
chr9_-_76692181 8.10 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr18_-_55588184 7.96 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr5_+_161848314 7.92 ENST00000437025.6
gamma-aminobutyric acid type A receptor subunit alpha1
chr5_+_161848536 7.88 ENST00000519621.2
ENST00000636573.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr15_-_101489697 7.85 ENST00000611967.4
ENST00000615296.4
ENST00000611716.5
ENST00000618548.4
ENST00000619160.4
ENST00000622483.4
ENST00000559417.2
proprotein convertase subtilisin/kexin type 6
chr6_+_32439866 7.78 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr4_+_37453914 7.76 ENST00000381980.9
ENST00000508175.5
chromosome 4 open reading frame 19
chr13_-_96053370 7.74 ENST00000376712.4
ENST00000397618.7
ENST00000376747.8
ENST00000376714.7
ENST00000638479.1
ENST00000621375.5
UDP-glucose glycoprotein glucosyltransferase 2
chr22_+_41800662 7.71 ENST00000402061.7
ENST00000255784.6
coiled-coil domain containing 134
chr7_-_954666 7.69 ENST00000265846.10
ENST00000649206.1
ArfGAP with dual PH domains 1
chr1_-_203351115 7.59 ENST00000354955.5
fibromodulin
chr10_+_91220603 7.49 ENST00000336126.6
polycomb group ring finger 5
chr8_+_11704151 7.46 ENST00000526716.5
ENST00000532059.6
ENST00000335135.8
ENST00000622443.3
GATA binding protein 4
chr4_-_152352800 7.44 ENST00000393956.9
F-box and WD repeat domain containing 7
chrX_-_155612928 7.36 ENST00000334398.8
trimethyllysine hydroxylase, epsilon
chr16_+_19168207 7.18 ENST00000355377.7
ENST00000568115.5
synaptotagmin 17
chrX_+_153972729 7.18 ENST00000369982.5
transmembrane protein 187
chr1_+_50108856 7.06 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr17_+_79024142 6.82 ENST00000579760.6
ENST00000339142.6
C1q and TNF related 1
chr1_+_205043165 6.80 ENST00000640428.1
contactin 2
chr5_-_175444132 6.80 ENST00000393752.3
dopamine receptor D1
chr1_-_154183199 6.76 ENST00000323144.12
ENST00000330188.13
ENST00000328159.9
ENST00000611659.4
tropomyosin 3
chrX_-_6228835 6.73 ENST00000381095.8
neuroligin 4 X-linked
chr1_+_205042960 6.71 ENST00000638378.1
contactin 2
chr5_-_179345423 6.53 ENST00000518335.3
ENST00000274609.5
ENST00000251582.12
ADAM metallopeptidase with thrombospondin type 1 motif 2
chr17_+_79024243 6.50 ENST00000311661.4
C1q and TNF related 1
chr11_-_62622149 6.45 ENST00000531383.5
beta-1,3-glucuronyltransferase 3
chr11_+_1840168 6.40 ENST00000381905.3
troponin I2, fast skeletal type
chr1_+_50109788 6.34 ENST00000651258.1
ELAV like RNA binding protein 4
chr12_+_54008961 6.34 ENST00000040584.6
homeobox C8
chr3_+_184276007 6.20 ENST00000359140.8
ENST00000404464.8
ENST00000357474.9
endothelin converting enzyme 2
chr3_-_48089203 6.19 ENST00000468075.2
ENST00000360240.10
microtubule associated protein 4
chr2_+_172735912 6.05 ENST00000409036.5
Rap guanine nucleotide exchange factor 4
chrX_+_49829260 5.99 ENST00000376141.5
ENST00000218068.7
PAGE family member 4
chr8_-_9150648 5.97 ENST00000310455.4
protein phosphatase 1 regulatory subunit 3B
chr19_+_13747887 5.88 ENST00000221554.13
ENST00000586666.5
coiled-coil domain containing 130
chr2_+_170816868 5.87 ENST00000358196.8
glutamate decarboxylase 1
chr7_+_128937917 5.82 ENST00000357234.10
ENST00000613821.4
ENST00000477535.5
ENST00000479582.5
ENST00000464557.5
ENST00000402030.6
interferon regulatory factor 5
chr17_+_19377721 5.80 ENST00000308406.9
ENST00000299612.11
mitogen-activated protein kinase 7
chr5_+_137889437 5.80 ENST00000508638.5
ENST00000508883.6
ENST00000502810.5
polycystin 2 like 2, transient receptor potential cation channel
chr3_+_124584625 5.79 ENST00000291478.9
ENST00000682363.1
ENST00000454902.1
kalirin RhoGEF kinase
chr1_+_205504592 5.75 ENST00000506784.5
ENST00000360066.6
cyclin dependent kinase 18
chr11_-_10568571 5.60 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_175192769 5.60 ENST00000423313.6
KIAA0040
chr8_-_56445941 5.42 ENST00000517415.1
ENST00000314922.3
proenkephalin
chr1_+_205043204 5.37 ENST00000331830.7
contactin 2
chr11_-_60183011 5.36 ENST00000533023.5
ENST00000420732.6
ENST00000528851.6
membrane spanning 4-domains A6A
chr2_-_24360445 5.30 ENST00000443927.5
ENST00000406921.7
ENST00000412011.5
ENST00000355123.9
intersectin 2
chr5_+_141350081 5.27 ENST00000523390.2
ENST00000611598.1
protocadherin gamma subfamily B, 1
chr19_-_15125362 5.27 ENST00000527093.5
ilvB acetolactate synthase like
chr1_-_84690406 5.14 ENST00000605755.5
ENST00000342203.8
ENST00000437941.6
SSX family member 2 interacting protein
chr19_+_50358571 5.11 ENST00000652203.1
nuclear receptor subfamily 1 group H member 2
chrX_-_54998530 5.08 ENST00000545676.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_-_38005484 5.03 ENST00000373016.4
four and a half LIM domains 3
chr12_-_14843517 5.03 ENST00000228936.6
ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
chr9_-_112718021 5.01 ENST00000374234.1
ENST00000374242.9
ENST00000374236.5
INTS3 and NABP interacting protein
chr1_+_92299023 5.01 ENST00000610020.2
RNA polymerase II associated protein 2
chr20_+_20368096 4.94 ENST00000310227.3
INSM transcriptional repressor 1
chr7_+_26293025 4.85 ENST00000396376.5
sorting nexin 10
chr13_-_94712505 4.84 ENST00000376945.4
SRY-box transcription factor 21
chr4_+_61201223 4.80 ENST00000512091.6
adhesion G protein-coupled receptor L3
chr6_-_100464912 4.79 ENST00000369208.8
SIM bHLH transcription factor 1
chr19_+_50376447 4.78 ENST00000253727.10
ENST00000598168.5
ENST00000411902.6
ENST00000597790.5
ENST00000597130.5
ENST00000599105.5
nuclear receptor subfamily 1 group H member 2
chr11_-_19240936 4.65 ENST00000250024.9
E2F transcription factor 8
chr17_-_66220630 4.65 ENST00000585162.1
apolipoprotein H
chr4_+_70360751 4.65 ENST00000226460.5
submaxillary gland androgen regulated protein 3A
chr1_+_171314171 4.61 ENST00000367749.4
flavin containing dimethylaniline monoxygenase 4
chr5_+_112737847 4.60 ENST00000257430.9
ENST00000508376.6
APC regulator of WNT signaling pathway
chr11_-_60183191 4.59 ENST00000412309.6
membrane spanning 4-domains A6A
chr22_-_44312894 4.58 ENST00000381176.5
shisa like 1
chrX_-_6227180 4.48 ENST00000381093.6
neuroligin 4 X-linked
chr3_-_122793772 4.47 ENST00000306103.3
HSPB1 associated protein 1
chr15_-_55365231 4.46 ENST00000568543.1
cell cycle progression 1
chr21_-_7829587 4.39 ENST00000623803.1
ENST00000618699.3
potassium voltage-gated channel subfamily E regulatory subunit 1B
chr1_-_19979607 4.36 ENST00000400520.8
ENST00000482011.2
ENST00000649436.1
phospholipase A2 group IIA
chr3_+_50269140 4.35 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr17_-_1491610 4.33 ENST00000646049.1
myosin IC
chr6_+_122779707 4.26 ENST00000368444.8
ENST00000356535.4
fatty acid binding protein 7
chr1_-_153057504 4.21 ENST00000392653.3
small proline rich protein 2A
chr12_+_122203681 4.21 ENST00000546192.1
ENST00000324189.5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr11_-_10568650 4.20 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr3_+_44338452 4.14 ENST00000396078.7
T cell activation inhibitor, mitochondrial
chr2_-_70553638 4.07 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr11_-_62621977 4.07 ENST00000534026.5
ENST00000265471.10
beta-1,3-glucuronyltransferase 3
chr12_+_50104000 4.02 ENST00000548814.1
ENST00000301149.8
glycerol-3-phosphate dehydrogenase 1
chr22_+_30607203 4.01 ENST00000407817.3
transcobalamin 2
chr6_-_46954922 3.97 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr14_+_64715677 3.91 ENST00000634379.2
pleckstrin homology and RhoGEF domain containing G3
chr17_+_10697576 3.85 ENST00000379774.5
ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
chr7_+_131327863 3.83 ENST00000352689.11
muskelin 1
chr6_+_31137646 3.77 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr5_-_10307821 3.77 ENST00000296658.4
carboxymethylenebutenolidase homolog
chr4_+_70383123 3.72 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr17_+_44187210 3.68 ENST00000589785.1
ENST00000592825.1
ENST00000589184.5
transmembrane and ubiquitin like domain containing 2
chr17_-_19377876 3.64 ENST00000674596.1
ENST00000642870.2
B9 domain containing 1
chrY_+_6910682 3.61 ENST00000355162.6
ENST00000346432.3
ENST00000383032.6
transducin beta like 1 Y-linked
chr17_+_56834081 3.59 ENST00000572810.1
ENST00000284061.8
diacylglycerol kinase epsilon
chr14_-_105864247 3.57 ENST00000461719.1
immunoglobulin heavy joining 4
chrX_+_154458274 3.54 ENST00000369682.4
plexin A3
chr1_+_14924100 3.52 ENST00000361144.9
kazrin, periplakin interacting protein
chr3_-_48088800 3.51 ENST00000423088.5
microtubule associated protein 4
chr6_-_69699124 3.44 ENST00000651675.1
LMBR1 domain containing 1
chr3_-_42581936 3.41 ENST00000423701.6
ENST00000420163.1
ENST00000416880.5
ENST00000264454.8
ENST00000273156.11
SEC22 homolog C, vesicle trafficking protein
chrY_+_14524492 3.40 ENST00000339174.9
neuroligin 4 Y-linked
chr17_-_1491645 3.36 ENST00000361007.7
myosin IC
chr1_+_3690654 3.34 ENST00000378285.5
ENST00000378280.5
ENST00000378288.8
tumor protein p73
chr9_-_75088198 3.22 ENST00000376808.8
nicotinamide riboside kinase 1
chr14_+_104985758 3.20 ENST00000551606.5
ENST00000547315.6
clathrin binding box of aftiphilin containing 1
chr1_+_20139316 3.19 ENST00000375102.4
phospholipase A2 group IIF
chr11_-_74009077 3.18 ENST00000314032.9
ENST00000426995.2
uncoupling protein 3
chr21_-_35049238 3.18 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX family transcription factor 1
chr15_+_90872162 3.17 ENST00000680053.1
furin, paired basic amino acid cleaving enzyme
chr12_-_47725483 3.16 ENST00000422538.8
endonuclease, poly(U) specific
chr21_-_7829926 3.16 ENST00000622690.4
potassium voltage-gated channel subfamily E regulatory subunit 1B
chr1_-_212699817 3.16 ENST00000243440.2
basic leucine zipper ATF-like transcription factor 3
chr1_+_151060357 3.14 ENST00000368921.5
MLLT11 transcription factor 7 cofactor
chr2_+_170816562 3.13 ENST00000625689.2
ENST00000375272.5
glutamate decarboxylase 1
chr18_+_905103 3.12 ENST00000579794.1
adenylate cyclase activating polypeptide 1
chr20_+_58839741 3.12 ENST00000371098.6
ENST00000371075.7
ENST00000419558.7
ENST00000657090.1
GNAS complex locus
chr17_+_45620323 3.05 ENST00000634540.1
LINC02210-CRHR1 readthrough
chr2_-_73642413 3.05 ENST00000272425.4
N-acetyltransferase 8 (putative)
chr10_+_74825445 2.94 ENST00000649006.1
ENST00000649463.1
ENST00000372725.6
lysine acetyltransferase 6B
chr9_-_75088140 2.93 ENST00000361092.9
ENST00000376811.5
nicotinamide riboside kinase 1
chr11_-_74398378 2.93 ENST00000298198.5
phosphoglucomutase 2 like 1
chr1_-_114695613 2.92 ENST00000369538.4
adenosine monophosphate deaminase 1
chr3_+_139935176 2.91 ENST00000458420.7
calsyntenin 2
chr1_-_204196482 2.87 ENST00000367194.5
KiSS-1 metastasis suppressor
chr19_+_48965304 2.80 ENST00000331825.11
ferritin light chain
chr9_+_133459965 2.80 ENST00000540581.5
ENST00000542192.5
ENST00000291722.11
ENST00000316948.9
calcium channel flower domain containing 1
chr8_+_28317265 2.77 ENST00000301908.8
prepronociceptin
chr9_-_20622479 2.77 ENST00000380338.9
MLLT3 super elongation complex subunit
chr9_-_96619783 2.74 ENST00000375241.6
cell division cycle 14B
chr6_-_161274010 2.67 ENST00000366911.9
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr20_-_57710539 2.64 ENST00000395816.7
ENST00000347215.8
prostate transmembrane protein, androgen induced 1
chr5_-_160400025 2.61 ENST00000523213.1
ENST00000408953.4
zinc finger BED-type containing 8
chr2_-_144520315 2.61 ENST00000465070.5
ENST00000465308.5
ENST00000636471.1
ENST00000629520.2
ENST00000675069.1
ENST00000636026.2
ENST00000444559.5
zinc finger E-box binding homeobox 2
chr21_+_39657310 2.59 ENST00000380618.5
beta-1,3-galactosyltransferase 5
chr12_-_47725558 2.58 ENST00000229003.7
endonuclease, poly(U) specific
chr12_+_54497712 2.55 ENST00000293373.11
NCK associated protein 1 like
chr6_-_161274042 2.55 ENST00000320285.9
1-acylglycerol-3-phosphate O-acyltransferase 4
chrX_-_57136997 2.52 ENST00000374908.1
spindlin family member 2A
chr1_+_31576485 2.48 ENST00000457433.6
ENST00000271064.12
tubulointerstitial nephritis antigen like 1
chr15_+_83654075 2.46 ENST00000567476.1
ENST00000286744.10
ADAMTS like 3
chr6_-_25930678 2.43 ENST00000377850.8
solute carrier family 17 member 2
chr7_+_99828010 2.41 ENST00000631161.2
ENST00000354829.7
ENST00000342499.8
ENST00000417625.5
ENST00000415413.5
ENST00000444905.5
ENST00000222382.5
ENST00000312017.9
cytochrome P450 family 3 subfamily A member 43
chr9_-_96619378 2.39 ENST00000375240.7
ENST00000463569.5
cell division cycle 14B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 36.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
10.6 31.8 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
10.3 30.9 GO:0030185 nitric oxide transport(GO:0030185)
6.8 40.6 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
6.3 25.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
6.3 18.9 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
5.5 21.9 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
4.8 19.3 GO:0071418 cellular response to amine stimulus(GO:0071418)
4.6 13.7 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
3.8 15.4 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
3.8 19.2 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
3.8 11.5 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
3.4 30.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
3.3 9.9 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
3.1 9.4 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
2.7 13.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
2.6 7.8 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
2.5 7.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
2.2 11.0 GO:0032902 nerve growth factor production(GO:0032902)
1.9 11.3 GO:0021523 somatic motor neuron differentiation(GO:0021523)
1.9 7.5 GO:0003290 atrial septum secundum morphogenesis(GO:0003290) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
1.9 7.4 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.8 10.7 GO:0001826 inner cell mass cell differentiation(GO:0001826)
1.7 24.3 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
1.7 8.6 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
1.6 4.9 GO:0003358 noradrenergic neuron development(GO:0003358)
1.6 9.7 GO:0051012 microtubule sliding(GO:0051012)
1.6 3.1 GO:0090274 somatostatin secretion(GO:0070253) regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
1.4 5.8 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
1.4 15.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
1.4 40.5 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
1.4 6.8 GO:0035106 operant conditioning(GO:0035106)
1.4 5.4 GO:0051866 general adaptation syndrome(GO:0051866)
1.3 5.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.2 10.8 GO:0032790 ribosome disassembly(GO:0032790)
1.2 15.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.1 2.3 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.1 29.2 GO:0071420 cellular response to histamine(GO:0071420)
1.0 41.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.0 7.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.0 2.9 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.9 4.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.9 13.1 GO:0015889 cobalamin transport(GO:0015889)
0.9 2.6 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.8 9.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.8 5.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.8 4.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.8 4.0 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.7 8.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.7 9.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.7 7.7 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.7 2.1 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.6 5.8 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.6 8.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.6 8.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.6 1.8 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.6 4.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.5 4.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.5 4.7 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.5 1.5 GO:0006566 threonine metabolic process(GO:0006566)
0.5 4.6 GO:0032264 IMP salvage(GO:0032264)
0.5 1.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 4.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 7.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.4 3.5 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4 2.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.4 2.2 GO:0006116 NADH oxidation(GO:0006116)
0.4 6.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 2.8 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4 1.5 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.4 1.5 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.4 3.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 5.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 20.9 GO:0097484 dendrite extension(GO:0097484)
0.4 1.5 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.4 4.0 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.4 4.9 GO:0032494 response to peptidoglycan(GO:0032494)
0.3 6.5 GO:0031053 primary miRNA processing(GO:0031053)
0.3 23.7 GO:0007602 phototransduction(GO:0007602)
0.3 15.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.3 5.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 2.9 GO:0019388 galactose catabolic process(GO:0019388)
0.3 5.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.3 9.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 5.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.3 4.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 4.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.3 1.9 GO:1902306 negative regulation of sodium ion transport(GO:0010766) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.3 2.2 GO:0006013 mannose metabolic process(GO:0006013)
0.3 4.6 GO:0042737 drug catabolic process(GO:0042737)
0.2 1.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 2.8 GO:0007379 segment specification(GO:0007379)
0.2 13.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 2.9 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.2 3.3 GO:0035878 nail development(GO:0035878)
0.2 4.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 6.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.2 3.8 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.2 16.3 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.2 3.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 6.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.2 3.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 6.5 GO:0030199 collagen fibril organization(GO:0030199)
0.2 4.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 8.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.2 0.5 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.2 3.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 2.6 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 1.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 5.5 GO:0006525 arginine metabolic process(GO:0006525)
0.2 1.6 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 3.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.4 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 8.9 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.8 GO:0042713 sperm ejaculation(GO:0042713)
0.1 4.3 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.9 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 4.4 GO:0050919 negative chemotaxis(GO:0050919)
0.1 4.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 18.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 6.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 2.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 5.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 4.8 GO:0001942 hair follicle development(GO:0001942) skin epidermis development(GO:0098773)
0.1 4.1 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 1.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 3.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.8 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 0.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 4.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 3.8 GO:0030048 actin filament-based movement(GO:0030048)
0.1 1.8 GO:0033189 response to vitamin A(GO:0033189)
0.0 1.1 GO:0002507 tolerance induction(GO:0002507)
0.0 1.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 4.9 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 4.5 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 6.3 GO:0048705 skeletal system morphogenesis(GO:0048705)
0.0 3.7 GO:0072164 ureteric bud development(GO:0001657) mesonephros development(GO:0001823) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 4.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.4 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 5.0 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 4.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 3.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 3.9 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 13.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.5 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 2.9 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 3.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
15.0 45.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
7.7 30.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
4.4 30.6 GO:0044326 dendritic spine neck(GO:0044326)
4.0 28.1 GO:1990761 growth cone lamellipodium(GO:1990761)
2.2 24.3 GO:0043203 axon hillock(GO:0043203)
1.9 15.4 GO:0033647 host cell cytoplasm(GO:0030430) host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) host cell cytoplasm part(GO:0033655)
1.9 9.3 GO:0001652 granular component(GO:0001652)
1.5 7.7 GO:0045160 myosin I complex(GO:0045160)
1.3 5.0 GO:0070876 SOSS complex(GO:0070876)
1.1 7.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.1 13.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.0 37.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.9 13.7 GO:0005687 U4 snRNP(GO:0005687)
0.8 21.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.8 5.4 GO:0032280 symmetric synapse(GO:0032280)
0.7 29.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.7 2.8 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.7 4.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.7 4.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7 9.3 GO:0000124 SAGA complex(GO:0000124)
0.7 8.6 GO:0060077 inhibitory synapse(GO:0060077)
0.6 2.9 GO:0032044 DSIF complex(GO:0032044)
0.5 6.0 GO:0042587 glycogen granule(GO:0042587)
0.5 6.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.5 18.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.4 11.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 7.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 8.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.4 6.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 4.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.4 52.0 GO:0043202 lysosomal lumen(GO:0043202)
0.3 3.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 6.4 GO:0005861 troponin complex(GO:0005861)
0.3 7.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 4.2 GO:1990909 Wnt signalosome(GO:1990909)
0.2 3.6 GO:0036038 MKS complex(GO:0036038)
0.2 2.6 GO:0031209 SCAR complex(GO:0031209)
0.2 8.8 GO:0048786 presynaptic active zone(GO:0048786)
0.2 15.5 GO:0005581 collagen trimer(GO:0005581)
0.2 7.7 GO:0001533 cornified envelope(GO:0001533)
0.2 10.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 5.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.6 GO:0016013 syntrophin complex(GO:0016013)
0.1 25.3 GO:0030426 growth cone(GO:0030426)
0.1 0.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 9.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 3.4 GO:0031201 SNARE complex(GO:0031201)
0.1 2.2 GO:0070461 SAGA-type complex(GO:0070461)
0.1 7.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 3.3 GO:1902555 endoribonuclease complex(GO:1902555)
0.1 15.4 GO:0005923 bicellular tight junction(GO:0005923)
0.1 6.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 39.0 GO:0043025 neuronal cell body(GO:0043025)
0.1 4.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.3 GO:0008305 integrin complex(GO:0008305)
0.1 15.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 3.1 GO:0043195 terminal bouton(GO:0043195)
0.1 5.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 3.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.0 GO:0032982 myosin filament(GO:0032982)
0.0 1.1 GO:0031904 endosome lumen(GO:0031904)
0.0 5.0 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 13.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 7.6 GO:0001726 ruffle(GO:0001726)
0.0 1.5 GO:0002102 podosome(GO:0002102)
0.0 1.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 5.5 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 20.4 GO:0005615 extracellular space(GO:0005615)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 5.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 40.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
5.6 45.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
5.5 21.9 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
4.8 19.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
4.5 26.9 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
4.4 30.9 GO:0030492 hemoglobin binding(GO:0030492)
4.1 12.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
2.9 11.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
2.6 10.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
2.4 30.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) steroid hormone binding(GO:1990239)
2.4 9.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
2.0 9.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.7 6.8 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.6 31.7 GO:0048156 tau protein binding(GO:0048156)
1.5 6.2 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.4 8.3 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.3 3.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.3 5.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.2 4.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.1 13.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
1.1 8.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.0 5.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.0 7.0 GO:0001515 opioid peptide activity(GO:0001515)
0.9 13.1 GO:0031419 cobalamin binding(GO:0031419)
0.9 7.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.9 15.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.9 7.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.8 4.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.8 5.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.8 4.0 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.8 3.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.8 7.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.7 31.3 GO:0017091 AU-rich element binding(GO:0017091)
0.7 11.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.7 3.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.7 2.2 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.7 22.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.7 7.5 GO:0051525 NFAT protein binding(GO:0051525)
0.7 4.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 8.4 GO:0015248 sterol transporter activity(GO:0015248)
0.6 36.9 GO:0015485 cholesterol binding(GO:0015485)
0.6 5.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.6 2.3 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.6 7.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.5 8.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.5 1.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.5 4.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 19.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 3.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 2.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.5 1.9 GO:0035276 ethanol binding(GO:0035276)
0.5 6.4 GO:0031014 troponin T binding(GO:0031014)
0.4 4.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 2.5 GO:0004882 androgen receptor activity(GO:0004882)
0.4 10.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 7.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 8.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 4.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.3 1.5 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.3 25.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 4.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 1.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.3 3.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.3 3.3 GO:0038132 neuregulin binding(GO:0038132)
0.3 7.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 9.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 19.6 GO:0043621 protein self-association(GO:0043621)
0.3 2.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3 14.8 GO:0030552 cAMP binding(GO:0030552)
0.3 28.8 GO:0005518 collagen binding(GO:0005518)
0.2 2.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 4.4 GO:0038191 neuropilin binding(GO:0038191)
0.2 18.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 0.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 26.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 2.8 GO:0008199 ferric iron binding(GO:0008199)
0.2 5.8 GO:0004707 MAP kinase activity(GO:0004707)
0.2 3.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 4.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 10.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 3.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 15.4 GO:0005507 copper ion binding(GO:0005507)
0.2 1.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 3.8 GO:0005522 profilin binding(GO:0005522)
0.2 9.5 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 7.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 4.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 2.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 0.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 2.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 2.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 3.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 15.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.7 GO:0070330 aromatase activity(GO:0070330)
0.1 15.5 GO:0005262 calcium channel activity(GO:0005262)
0.1 5.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 4.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 1.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 10.7 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.6 GO:0050998 dystroglycan binding(GO:0002162) nitric-oxide synthase binding(GO:0050998)
0.1 13.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 11.3 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.1 4.0 GO:0061733 histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1 6.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 8.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 4.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 2.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 11.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 10.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.6 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 2.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 3.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 4.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.9 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 40.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.6 32.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.6 37.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 25.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.5 14.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.3 32.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.3 46.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 9.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 5.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 5.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 9.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 3.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 7.4 PID MYC PATHWAY C-MYC pathway
0.2 2.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 5.8 ST GA12 PATHWAY G alpha 12 Pathway
0.1 7.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 7.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 14.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 7.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 16.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 19.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 4.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 4.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 45.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.1 16.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.8 38.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.8 29.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.6 19.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 24.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.6 30.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.5 7.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.5 7.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.5 9.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 10.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 24.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 5.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 10.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 20.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 14.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.9 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2 30.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 8.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 6.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 7.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 8.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 4.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 4.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 4.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 3.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 8.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 6.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 7.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 5.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 20.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 4.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 8.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 2.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 12.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 7.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 7.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 8.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 8.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 2.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 4.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism