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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for AACACUG

Z-value: 1.17

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miRNA associated with seed AACACUG

NamemiRBASE accession
hsa-miR-141-3p
MIMAT0000432
hsa-miR-200a-3p
MIMAT0000682

Activity profile of AACACUG motif

Sorted Z-values of AACACUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_118916082 2.38 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr10_+_31608054 2.31 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr7_-_47621736 1.97 ENST00000311160.9
TNS3
tensin 3
chr14_-_57735528 1.85 ENST00000340918.7
ENST00000413566.2
EXOC5
exocyst complex component 5
chr17_-_63052929 1.84 ENST00000439174.2
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr4_+_57138437 1.71 ENST00000504228.1
ENST00000541073.1
KIAA1211
KIAA1211
chr8_-_67525473 1.70 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr1_+_95582881 1.70 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr7_-_108096822 1.59 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr13_+_98605902 1.56 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5
importin 5
chr2_+_45878790 1.36 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr1_-_150208291 1.35 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr7_-_156803329 1.33 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr17_+_47074758 1.27 ENST00000290341.3
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr1_+_218519577 1.24 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr2_+_46926048 1.24 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr10_-_33623564 1.22 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chrX_+_21857717 1.14 ENST00000379484.5
MBTPS2
membrane-bound transcription factor peptidase, site 2
chr21_+_38071430 1.13 ENST00000290399.6
SIM2
single-minded family bHLH transcription factor 2
chr12_+_41086297 1.11 ENST00000551295.2
CNTN1
contactin 1
chr11_-_115375107 1.11 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr7_+_21467642 1.09 ENST00000222584.3
ENST00000432066.2
SP4
Sp4 transcription factor
chr6_-_18265050 1.08 ENST00000397239.3
DEK
DEK oncogene
chr6_+_127439749 1.05 ENST00000356698.4
RSPO3
R-spondin 3
chr9_-_6015607 1.04 ENST00000259569.5
RANBP6
RAN binding protein 6
chr11_+_86748863 1.02 ENST00000340353.7
TMEM135
transmembrane protein 135
chr14_-_35182994 1.02 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr17_-_8534067 1.01 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr6_-_127780510 1.01 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr11_-_105892937 1.01 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr11_+_122526383 0.98 ENST00000284273.5
UBASH3B
ubiquitin associated and SH3 domain containing B
chr15_+_69591235 0.97 ENST00000395407.2
ENST00000558684.1
PAQR5
progestin and adipoQ receptor family member V
chr19_-_33555780 0.92 ENST00000254260.3
ENST00000400226.4
RHPN2
rhophilin, Rho GTPase binding protein 2
chr17_-_49198216 0.92 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr17_-_42908155 0.90 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr9_+_90112741 0.89 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr5_-_32444828 0.89 ENST00000265069.8
ZFR
zinc finger RNA binding protein
chr3_+_152017181 0.86 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr3_+_62304712 0.85 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chr8_-_71316021 0.84 ENST00000452400.2
NCOA2
nuclear receptor coactivator 2
chr15_+_77712993 0.81 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr15_+_57210818 0.81 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr20_+_277737 0.78 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr7_-_82073109 0.77 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr1_-_231560790 0.77 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr2_-_72375167 0.77 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr10_+_14920843 0.77 ENST00000433779.1
ENST00000378325.3
ENST00000354919.6
ENST00000313519.5
ENST00000420416.1
SUV39H2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr21_-_15755446 0.76 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr17_-_29151794 0.76 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr9_+_116638562 0.75 ENST00000374126.5
ENST00000288466.7
ZNF618
zinc finger protein 618
chr10_+_89622870 0.74 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr7_-_75988321 0.73 ENST00000307630.3
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr3_+_25469724 0.73 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr10_+_69644404 0.72 ENST00000212015.6
SIRT1
sirtuin 1
chr1_+_40723779 0.72 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr2_+_60983361 0.71 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr12_+_125478241 0.71 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr17_-_78450398 0.71 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr5_+_169010638 0.69 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr14_-_30396948 0.69 ENST00000331968.5
PRKD1
protein kinase D1
chr20_-_22565101 0.68 ENST00000419308.2
FOXA2
forkhead box A2
chr3_-_33686743 0.68 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr13_-_50367057 0.66 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr7_-_111846435 0.64 ENST00000437633.1
ENST00000428084.1
DOCK4
dedicator of cytokinesis 4
chr9_+_129622904 0.64 ENST00000319119.4
ZBTB34
zinc finger and BTB domain containing 34
chr13_+_93879085 0.63 ENST00000377047.4
GPC6
glypican 6
chr2_+_178257372 0.62 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr17_-_38821373 0.62 ENST00000394052.3
KRT222
keratin 222
chr1_-_166845515 0.61 ENST00000367874.4
TADA1
transcriptional adaptor 1
chr3_+_158991025 0.61 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_+_84543734 0.60 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_74867509 0.59 ENST00000426327.3
GATSL2
GATS protein-like 2
chr6_-_127840453 0.59 ENST00000556132.1
SOGA3
SOGA family member 3
chr3_+_113465866 0.58 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr12_+_54332535 0.57 ENST00000243056.3
HOXC13
homeobox C13
chr17_-_41856305 0.56 ENST00000397937.2
ENST00000226004.3
DUSP3
dual specificity phosphatase 3
chr17_-_202579 0.56 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL
rabphilin 3A-like (without C2 domains)
chr10_-_94333784 0.56 ENST00000265986.6
IDE
insulin-degrading enzyme
chr17_+_36508111 0.55 ENST00000331159.5
ENST00000577233.1
SOCS7
suppressor of cytokine signaling 7
chr1_-_211752073 0.55 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr17_+_35294075 0.54 ENST00000254457.5
LHX1
LIM homeobox 1
chr15_+_62853562 0.54 ENST00000561311.1
TLN2
talin 2
chr2_+_26256938 0.53 ENST00000264710.4
RAB10
RAB10, member RAS oncogene family
chr12_-_109125285 0.52 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr15_-_51058005 0.52 ENST00000261854.5
SPPL2A
signal peptide peptidase like 2A
chr20_+_3776371 0.52 ENST00000245960.5
CDC25B
cell division cycle 25B
chr2_-_86094764 0.52 ENST00000393808.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr8_-_110346614 0.51 ENST00000239690.4
NUDCD1
NudC domain containing 1
chr2_-_152684977 0.50 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr4_+_183164574 0.50 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr19_+_48898132 0.50 ENST00000263269.3
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr20_+_33814457 0.49 ENST00000246186.6
MMP24
matrix metallopeptidase 24 (membrane-inserted)
chr4_-_184580353 0.49 ENST00000326397.5
RWDD4
RWD domain containing 4
chr4_-_100871506 0.49 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr10_+_115803650 0.48 ENST00000369295.2
ADRB1
adrenoceptor beta 1
chr6_-_37665751 0.48 ENST00000297153.7
ENST00000434837.3
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr15_+_52311398 0.48 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr17_-_46671323 0.47 ENST00000239151.5
HOXB5
homeobox B5
chr16_-_71758602 0.47 ENST00000568954.1
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr13_+_42846272 0.47 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr7_-_135662056 0.46 ENST00000393085.3
ENST00000435723.1
MTPN
myotrophin
chr10_+_93558069 0.46 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr1_-_200379180 0.46 ENST00000294740.3
ZNF281
zinc finger protein 281
chr10_+_70320413 0.46 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr17_+_57642886 0.45 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr3_+_61547585 0.44 ENST00000295874.10
ENST00000474889.1
PTPRG
protein tyrosine phosphatase, receptor type, G
chr15_-_65715401 0.44 ENST00000352385.2
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr3_+_159557637 0.44 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr9_-_16870704 0.44 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr8_+_26149007 0.44 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr7_-_11871815 0.44 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr1_-_232697304 0.43 ENST00000366630.1
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr17_-_19771216 0.43 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr1_-_205180664 0.43 ENST00000367161.3
ENST00000367162.3
ENST00000367160.4
DSTYK
dual serine/threonine and tyrosine protein kinase
chr3_-_195808952 0.43 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chr2_-_100939195 0.42 ENST00000393437.3
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr17_-_4269768 0.42 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr7_-_156685890 0.41 ENST00000353442.5
LMBR1
limb development membrane protein 1
chrX_-_119694538 0.41 ENST00000371322.5
CUL4B
cullin 4B
chr12_-_131323719 0.41 ENST00000392373.2
STX2
syntaxin 2
chr14_+_96829814 0.41 ENST00000555181.1
ENST00000553699.1
ENST00000554182.1
GSKIP
GSK3B interacting protein
chr2_-_240322643 0.40 ENST00000345617.3
HDAC4
histone deacetylase 4
chr5_-_133561752 0.39 ENST00000519718.1
ENST00000481195.1
CTD-2410N18.5
PPP2CA
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr5_+_56205081 0.39 ENST00000285947.2
ENST00000541720.1
SETD9
SET domain containing 9
chr5_-_146833485 0.39 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr3_-_48229846 0.39 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr20_+_10199468 0.39 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr20_+_47538357 0.39 ENST00000371917.4
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr20_-_57617831 0.38 ENST00000371033.5
ENST00000355937.4
SLMO2
slowmo homolog 2 (Drosophila)
chr7_+_43152191 0.38 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr2_-_167232484 0.38 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr2_-_175499294 0.38 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr16_+_53088885 0.38 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_-_6388537 0.37 ENST00000313324.4
ENST00000530143.1
FAM220A
family with sequence similarity 220, member A
chr7_+_35840542 0.37 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr1_+_244214577 0.37 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr6_-_94129244 0.37 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chr14_+_36295504 0.36 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr6_+_17281573 0.36 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr5_-_43313574 0.36 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr13_+_53226963 0.36 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr11_+_32914579 0.36 ENST00000399302.2
QSER1
glutamine and serine rich 1
chr3_+_179065474 0.35 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr2_+_206547215 0.35 ENST00000360409.3
ENST00000540178.1
ENST00000540841.1
ENST00000355117.4
ENST00000450507.1
ENST00000417189.1
NRP2
neuropilin 2
chrX_+_118370211 0.35 ENST00000217971.7
PGRMC1
progesterone receptor membrane component 1
chr5_-_56247935 0.35 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
MIER3
mesoderm induction early response 1, family member 3
chr2_-_37193606 0.34 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr1_+_100818009 0.34 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr3_+_73045936 0.34 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr14_-_31676964 0.34 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr3_+_152552685 0.34 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr3_+_141205852 0.33 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr3_-_125313934 0.33 ENST00000296220.5
OSBPL11
oxysterol binding protein-like 11
chr4_-_186125077 0.33 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
KIAA1430
chr3_-_88108192 0.33 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr8_+_124780672 0.32 ENST00000521166.1
ENST00000334705.7
FAM91A1
family with sequence similarity 91, member A1
chr13_-_31038370 0.32 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr17_-_46178527 0.32 ENST00000393408.3
CBX1
chromobox homolog 1
chr5_+_118407053 0.32 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chrX_-_131352152 0.32 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr17_-_1928621 0.31 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1
chr3_+_112709804 0.31 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr17_+_66508537 0.31 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_-_41510656 0.31 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr2_+_139259324 0.31 ENST00000280098.4
SPOPL
speckle-type POZ protein-like
chr3_-_72496035 0.31 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr2_+_10861775 0.31 ENST00000272238.4
ENST00000381661.3
ATP6V1C2
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
chr12_+_22778009 0.31 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr8_-_55014415 0.31 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1
lysophospholipase I
chr12_-_76478686 0.31 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr4_-_40631859 0.30 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr1_+_218458625 0.30 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr1_-_225840747 0.29 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr10_+_112404132 0.29 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr3_-_142682178 0.28 ENST00000340634.3
PAQR9
progestin and adipoQ receptor family member IX
chr5_+_112312416 0.28 ENST00000389063.2
DCP2
decapping mRNA 2
chr4_-_140098339 0.28 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr17_-_58603568 0.27 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr17_+_30771279 0.27 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_-_159832438 0.27 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr5_-_168006591 0.27 ENST00000239231.6
PANK3
pantothenate kinase 3
chr2_+_169312350 0.27 ENST00000305747.6
CERS6
ceramide synthase 6
chr3_+_132136331 0.26 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr13_-_73356009 0.26 ENST00000377780.4
ENST00000377767.4
DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr2_+_228336849 0.26 ENST00000409979.2
ENST00000310078.8
AGFG1
ArfGAP with FG repeats 1
chr4_-_76598296 0.26 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr4_-_68566832 0.26 ENST00000420827.2
ENST00000322244.5
UBA6
ubiquitin-like modifier activating enzyme 6
chr14_+_97263641 0.26 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr6_+_64281906 0.26 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr20_+_46130601 0.25 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr18_+_32558208 0.24 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr3_+_155588300 0.24 ENST00000496455.2
GMPS
guanine monphosphate synthase
chr8_+_20054878 0.24 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr5_-_142783175 0.24 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_27621125 0.24 ENST00000579665.1
ENST00000225388.4
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr17_-_40428359 0.24 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr2_-_225450013 0.24 ENST00000264414.4
CUL3
cullin 3
chr9_-_74980113 0.23 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr1_-_243418344 0.23 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr11_+_101981169 0.23 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of AACACUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.4 1.2 GO:0042704 uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795)
0.3 1.4 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.3 0.8 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.3 0.8 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 1.2 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.7 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.2 0.7 GO:0030327 prenylated protein catabolic process(GO:0030327) CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 2.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 0.8 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.2 0.7 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 1.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.5 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.2 0.5 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.2 1.2 GO:0021592 fourth ventricle development(GO:0021592)
0.2 0.9 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 2.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.6 GO:1901143 insulin catabolic process(GO:1901143)
0.1 1.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.6 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.9 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.8 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.3 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 1.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 1.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.8 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.6 GO:0097501 stress response to metal ion(GO:0097501)
0.1 1.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 2.7 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 0.3 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1 0.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.2 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1 0.7 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.3 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.8 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 1.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 1.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.4 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 1.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.1 GO:0021644 vagus nerve morphogenesis(GO:0021644) chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.3 GO:0021764 amygdala development(GO:0021764)
0.0 0.7 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.5 GO:0007144 female meiosis I(GO:0007144)
0.0 0.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) regulation of rRNA processing(GO:2000232) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.7 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0051643 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) endoplasmic reticulum localization(GO:0051643)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.6 GO:0033572 transferrin transport(GO:0033572)
0.0 0.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 2.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.9 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 1.0 GO:0090140 response to food(GO:0032094) regulation of mitochondrial fission(GO:0090140)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 1.3 GO:0043486 histone exchange(GO:0043486)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0061304 cerebellum vasculature development(GO:0061300) retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.9 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.7 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.5 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0071203 WASH complex(GO:0071203)
0.1 1.2 GO:0097443 sorting endosome(GO:0097443)
0.1 0.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.7 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.1 1.6 GO:0043194 axon initial segment(GO:0043194)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 2.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 0.8 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 0.7 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.2 1.8 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 0.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.6 GO:0031626 beta-endorphin binding(GO:0031626)
0.2 0.7 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.2 0.7 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 0.5 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 0.8 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.2 0.5 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.2 0.9 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047)
0.1 1.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 3.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.4 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.6 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 1.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 1.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 4.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 1.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0051538 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 1.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 2.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.9 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.7 PID IGF1 PATHWAY IGF1 pathway
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 2.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.5 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 0.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.6 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 2.3 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type