Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for AIRE

Z-value: 0.33

Motif logo

logo of

Transcription factors associated with AIRE

Gene Symbol Gene ID Gene Info
AIRE
ENSG00000160224.12 autoimmune regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
AIREhg19_v2_chr21_+_45705752_45705767-0.097.0e-01Click!

Activity profile of AIRE motif

Sorted Z-values of AIRE motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_31147020 0.59 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr1_+_79115503 0.58 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chrM_+_12331 0.57 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chrM_-_14670 0.57 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr11_-_327537 0.55 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr19_-_52551814 0.48 ENST00000594154.1
ENST00000598745.1
ENST00000597273.1
ZNF432
zinc finger protein 432
chr3_+_189507460 0.46 ENST00000434928.1
TP63
tumor protein p63
chr12_+_75874580 0.45 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr7_-_87936195 0.45 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
STEAP4
STEAP family member 4
chr11_+_35211511 0.44 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr19_-_52552051 0.44 ENST00000221315.5
ZNF432
zinc finger protein 432
chr22_+_36649170 0.43 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
APOL1
apolipoprotein L, 1
chr12_+_75874984 0.42 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr4_-_120222076 0.42 ENST00000504110.1
C4orf3
chromosome 4 open reading frame 3
chrM_+_14741 0.35 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr22_+_36649056 0.35 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
APOL1
apolipoprotein L, 1
chr12_-_50677255 0.34 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chrM_+_4431 0.34 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chrM_+_7586 0.34 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr16_-_31146961 0.33 ENST00000567531.1
PRSS8
protease, serine, 8
chr20_+_44637526 0.33 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chrM_+_8366 0.30 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr21_+_39644305 0.30 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr21_+_39644172 0.29 ENST00000398932.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr21_+_39644395 0.29 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr21_+_39644214 0.25 ENST00000438657.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr9_-_21482312 0.25 ENST00000448696.3
IFNE
interferon, epsilon
chr20_+_12989596 0.25 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr10_-_4720333 0.24 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr12_+_7282795 0.22 ENST00000266546.6
CLSTN3
calsyntenin 3
chr19_-_21950362 0.21 ENST00000358296.6
ZNF100
zinc finger protein 100
chr19_-_36304201 0.21 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr13_-_46756351 0.21 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_11455900 0.20 ENST00000588790.1
CCDC159
coiled-coil domain containing 159
chr12_+_75874460 0.20 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr15_+_52043758 0.19 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr1_+_174843548 0.18 ENST00000478442.1
ENST00000465412.1
RABGAP1L
RAB GTPase activating protein 1-like
chr19_-_23869999 0.18 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675
zinc finger protein 675
chr6_-_33266687 0.18 ENST00000444031.2
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr10_+_127661942 0.18 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr7_-_64467031 0.18 ENST00000394323.2
ERV3-1
endogenous retrovirus group 3, member 1
chr4_-_186696425 0.17 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr16_-_29499154 0.17 ENST00000354563.5
RP11-231C14.4
Uncharacterized protein
chr7_+_116451100 0.16 ENST00000464223.1
ENST00000484325.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr4_+_69917078 0.15 ENST00000502942.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chrM_+_5824 0.15 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr19_-_23869970 0.15 ENST00000601010.1
ZNF675
zinc finger protein 675
chr12_-_59175485 0.14 ENST00000550678.1
ENST00000552201.1
RP11-767I20.1
RP11-767I20.1
chr4_-_57524061 0.14 ENST00000508121.1
HOPX
HOP homeobox
chr19_+_16607122 0.14 ENST00000221671.3
ENST00000594035.1
ENST00000599550.1
ENST00000594813.1
C19orf44
chromosome 19 open reading frame 44
chr5_+_667759 0.14 ENST00000594226.1
AC026740.1
Uncharacterized protein
chr4_+_71587669 0.14 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr1_+_40840320 0.13 ENST00000372708.1
SMAP2
small ArfGAP2
chr4_+_71588372 0.13 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr19_-_36643329 0.13 ENST00000589154.1
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr13_-_26795840 0.13 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr1_-_35497506 0.13 ENST00000317538.5
ENST00000373340.2
ENST00000357182.4
ZMYM6
zinc finger, MYM-type 6
chr22_-_32767017 0.12 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr15_+_52043813 0.12 ENST00000435126.2
TMOD2
tropomodulin 2 (neuronal)
chr12_-_113772835 0.12 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
SLC8B1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr10_-_75682535 0.12 ENST00000409178.1
C10orf55
chromosome 10 open reading frame 55
chr1_+_36038971 0.12 ENST00000373235.3
TFAP2E
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr9_+_71986182 0.12 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr21_+_30502806 0.12 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr16_+_14802801 0.11 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr15_-_83209210 0.11 ENST00000561157.1
ENST00000330244.6
RPS17L
ribosomal protein S17-like
chr8_+_128748308 0.11 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr6_+_22221010 0.10 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr1_-_52344471 0.10 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr12_+_55248289 0.10 ENST00000308796.6
MUCL1
mucin-like 1
chr7_+_142374104 0.10 ENST00000604952.1
MTRNR2L6
MT-RNR2-like 6
chr19_-_16606988 0.09 ENST00000269881.3
CALR3
calreticulin 3
chr4_-_16085657 0.09 ENST00000543373.1
PROM1
prominin 1
chr9_-_25678856 0.09 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr6_+_42584847 0.09 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr4_+_1385340 0.09 ENST00000324803.4
CRIPAK
cysteine-rich PAK1 inhibitor
chr19_-_16606930 0.09 ENST00000600762.1
CALR3
calreticulin 3
chr10_+_115511213 0.09 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr3_-_121468602 0.09 ENST00000340645.5
GOLGB1
golgin B1
chr20_+_58203664 0.08 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr2_+_219840955 0.08 ENST00000598002.1
ENST00000432733.1
LINC00608
long intergenic non-protein coding RNA 608
chr12_-_64784471 0.08 ENST00000333722.5
C12orf56
chromosome 12 open reading frame 56
chr5_-_38845812 0.08 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
CTD-2127H9.1
chr18_+_39739223 0.08 ENST00000601948.1
LINC00907
long intergenic non-protein coding RNA 907
chr20_+_44036900 0.08 ENST00000443296.1
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr6_-_32806506 0.07 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr20_+_44036620 0.07 ENST00000372710.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_+_18208603 0.07 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr11_+_107650219 0.07 ENST00000398067.1
AP001024.1
Uncharacterized protein
chr11_-_26744908 0.07 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr9_+_117904097 0.07 ENST00000374016.1
DEC1
deleted in esophageal cancer 1
chr17_+_41857793 0.07 ENST00000449302.3
C17orf105
chromosome 17 open reading frame 105
chr3_-_176914191 0.07 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_+_174670143 0.07 ENST00000367687.1
ENST00000347255.2
RABGAP1L
RAB GTPase activating protein 1-like
chr14_-_24911971 0.07 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr2_+_179316163 0.06 ENST00000409117.3
DFNB59
deafness, autosomal recessive 59
chr1_+_207669573 0.06 ENST00000400960.2
ENST00000534202.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr4_-_4544061 0.06 ENST00000507908.1
STX18
syntaxin 18
chr19_-_4902877 0.06 ENST00000381781.2
ARRDC5
arrestin domain containing 5
chr3_-_121468513 0.06 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr1_+_207669613 0.06 ENST00000367049.4
ENST00000529814.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr19_-_47249679 0.06 ENST00000263280.6
STRN4
striatin, calmodulin binding protein 4
chr1_-_152297679 0.06 ENST00000368799.1
FLG
filaggrin
chr12_+_12202785 0.06 ENST00000586576.1
ENST00000464885.2
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr10_-_13350447 0.06 ENST00000429930.1
AL138764.1
Uncharacterized protein
chr2_+_204732487 0.05 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr10_+_115511434 0.05 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr14_-_24912047 0.05 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr19_+_53517174 0.05 ENST00000602168.1
ERVV-1
endogenous retrovirus group V, member 1
chr1_+_96208646 0.05 ENST00000603401.1
RP11-286B14.2
RP11-286B14.2
chr7_+_80255472 0.05 ENST00000428497.1
CD36
CD36 molecule (thrombospondin receptor)
chr12_+_48516463 0.05 ENST00000546465.1
PFKM
phosphofructokinase, muscle
chr5_+_122181184 0.05 ENST00000513881.1
SNX24
sorting nexin 24
chr4_-_88450535 0.05 ENST00000541496.1
SPARCL1
SPARC-like 1 (hevin)
chr19_-_10491234 0.05 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr2_+_38177620 0.05 ENST00000402091.3
RMDN2
regulator of microtubule dynamics 2
chr17_-_39150385 0.05 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr9_-_70429731 0.05 ENST00000377413.1
FOXD4L4
forkhead box D4-like 4
chr16_+_50914085 0.04 ENST00000576842.1
CTD-2034I21.2
CTD-2034I21.2
chr11_+_45376922 0.04 ENST00000524410.1
ENST00000524488.1
ENST00000524565.1
RP11-430H10.1
RP11-430H10.1
chrX_-_49041242 0.04 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3
prickle homolog 3 (Drosophila)
chrX_-_153191674 0.04 ENST00000350060.5
ENST00000370016.1
ARHGAP4
Rho GTPase activating protein 4
chr19_-_59084922 0.04 ENST00000215057.2
ENST00000599369.1
MZF1
myeloid zinc finger 1
chr14_-_46185155 0.04 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr10_+_82300575 0.04 ENST00000313455.4
SH2D4B
SH2 domain containing 4B
chr11_+_6947647 0.04 ENST00000278319.5
ZNF215
zinc finger protein 215
chr19_+_56751773 0.04 ENST00000600684.1
ZSCAN5D
zinc finger and SCAN domain containing 5D
chr8_+_104384616 0.04 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr2_+_207804278 0.04 ENST00000272852.3
CPO
carboxypeptidase O
chr6_+_167525277 0.04 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr6_+_168434678 0.04 ENST00000496008.1
KIF25
kinesin family member 25
chrX_-_153191708 0.04 ENST00000393721.1
ENST00000370028.3
ARHGAP4
Rho GTPase activating protein 4
chr2_-_208994548 0.04 ENST00000282141.3
CRYGC
crystallin, gamma C
chr16_-_56223480 0.04 ENST00000565155.1
RP11-461O7.1
RP11-461O7.1
chr17_+_34171081 0.04 ENST00000585577.1
TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr2_-_127977654 0.04 ENST00000409327.1
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr3_-_123710199 0.04 ENST00000184183.4
ROPN1
rhophilin associated tail protein 1
chr1_-_167883327 0.04 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10
adenylate cyclase 10 (soluble)
chr7_-_36764004 0.04 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr1_+_241815577 0.04 ENST00000366552.2
ENST00000437684.2
WDR64
WD repeat domain 64
chr10_-_101841588 0.03 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr4_+_76649797 0.03 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr2_-_166060571 0.03 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr17_+_3323862 0.03 ENST00000291231.1
OR3A3
olfactory receptor, family 3, subfamily A, member 3
chr2_+_166150541 0.03 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr8_+_24241789 0.03 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr20_-_43150601 0.03 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3
serine incorporator 3
chr5_+_122181279 0.03 ENST00000395451.4
ENST00000506996.1
SNX24
sorting nexin 24
chr12_+_12202774 0.03 ENST00000589718.1
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr15_-_81202118 0.03 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chr13_+_103459704 0.03 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr9_-_79267432 0.03 ENST00000424866.1
PRUNE2
prune homolog 2 (Drosophila)
chr1_-_154600421 0.03 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr19_+_56280507 0.03 ENST00000341750.4
RFPL4AL1
ret finger protein-like 4A-like 1
chr15_+_83209620 0.03 ENST00000568285.1
RP11-379H8.1
Uncharacterized protein
chr7_-_36764142 0.03 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr6_-_169582835 0.03 ENST00000564830.1
RP11-417E7.2
RP11-417E7.2
chr12_-_15038779 0.03 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr2_-_198540719 0.03 ENST00000295049.4
RFTN2
raftlin family member 2
chr14_+_101123580 0.02 ENST00000556697.1
ENST00000360899.2
ENST00000553623.1
LINC00523
long intergenic non-protein coding RNA 523
chr16_-_20566616 0.02 ENST00000569163.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr3_-_49466686 0.02 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chrX_-_101694853 0.02 ENST00000372749.1
NXF2B
nuclear RNA export factor 2B
chr16_-_71518504 0.02 ENST00000565100.2
ZNF19
zinc finger protein 19
chr2_+_1417228 0.02 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
TPO
thyroid peroxidase
chr9_-_4666421 0.02 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr9_-_104198042 0.02 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr6_-_33864684 0.02 ENST00000506222.2
ENST00000533304.1
LINC01016
long intergenic non-protein coding RNA 1016
chr6_+_42141029 0.02 ENST00000372958.1
GUCA1A
guanylate cyclase activator 1A (retina)
chr22_+_40322595 0.02 ENST00000420971.1
ENST00000544756.1
GRAP2
GRB2-related adaptor protein 2
chr4_-_88450595 0.01 ENST00000434434.1
SPARCL1
SPARC-like 1 (hevin)
chr7_+_20686946 0.01 ENST00000443026.2
ENST00000406935.1
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr4_-_17513851 0.01 ENST00000281243.5
QDPR
quinoid dihydropteridine reductase
chr8_-_7220490 0.01 ENST00000400078.2
ZNF705G
zinc finger protein 705G
chr22_+_40322623 0.01 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr6_-_31514333 0.01 ENST00000376151.4
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr3_-_133648656 0.01 ENST00000408895.2
C3orf36
chromosome 3 open reading frame 36
chr12_+_12223867 0.01 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr4_-_88450612 0.01 ENST00000418378.1
ENST00000282470.6
SPARCL1
SPARC-like 1 (hevin)
chr9_+_71357171 0.01 ENST00000440050.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr7_-_137028498 0.01 ENST00000393083.2
PTN
pleiotrophin
chr11_+_94038759 0.01 ENST00000440961.2
ENST00000328458.4
FOLR4
folate receptor 4, delta (putative)
chr5_+_122181128 0.01 ENST00000261369.4
SNX24
sorting nexin 24
chr12_-_11139511 0.01 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr11_-_119249805 0.01 ENST00000527843.1
USP2
ubiquitin specific peptidase 2
chr3_-_139199565 0.01 ENST00000511956.1
RBP2
retinol binding protein 2, cellular
chr16_+_72088376 0.01 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr7_-_137028534 0.01 ENST00000348225.2
PTN
pleiotrophin
chr2_+_234686976 0.01 ENST00000389758.3
MROH2A
maestro heat-like repeat family member 2A
chr4_-_120243545 0.01 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr11_-_56310757 0.01 ENST00000528616.2
OR5M11
olfactory receptor, family 5, subfamily M, member 11
chr8_-_16043780 0.01 ENST00000445506.2
MSR1
macrophage scavenger receptor 1
chr16_-_89119355 0.01 ENST00000537498.1
CTD-2555A7.2
CTD-2555A7.2
chr2_-_166060552 0.01 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr8_+_86851932 0.00 ENST00000517368.1
CTA-392E5.1
CTA-392E5.1
chr6_+_36839616 0.00 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chr16_+_446713 0.00 ENST00000397722.1
ENST00000454619.1
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr19_-_2085323 0.00 ENST00000591638.1
MOB3A
MOB kinase activator 3A
chr9_+_42717234 0.00 ENST00000377590.1
FOXD4L2
forkhead box D4-like 2
chr1_-_91813006 0.00 ENST00000430465.1
HFM1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of AIRE

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.5 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.4 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.8 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.0 0.9 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.0 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0036457 keratohyalin granule(GO:0036457)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.5 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation