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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ALX1_ARX

Z-value: 0.72

Motif logo

Transcription factors associated with ALX1_ARX

Gene Symbol Gene ID Gene Info
ENSG00000180318.3 ALX homeobox 1
ENSG00000004848.6 aristaless related homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX1hg19_v2_chr12_+_85673868_85673885-0.941.3e-09Click!
ARXhg19_v2_chrX_-_25034065_25034088-0.911.7e-08Click!

Activity profile of ALX1_ARX motif

Sorted Z-values of ALX1_ARX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_61151306 3.63 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_+_102413726 3.54 ENST00000350878.4
mitogen-activated protein kinase kinase kinase kinase 4
chr4_+_69313145 3.22 ENST00000305363.4
transmembrane protease, serine 11E
chr10_+_24544249 2.78 ENST00000430453.2
KIAA1217
chr15_+_101417919 2.34 ENST00000561338.1
aldehyde dehydrogenase 1 family, member A3
chr9_+_124329336 2.27 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chr7_+_90338712 2.25 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr14_-_81893734 2.01 ENST00000555447.1
stonin 2
chr9_-_71869642 1.88 ENST00000600472.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr18_-_21891460 1.83 ENST00000357041.4
oxysterol binding protein-like 1A
chr11_-_96076334 1.82 ENST00000524717.1
mastermind-like 2 (Drosophila)
chr12_+_14572070 1.82 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
activating transcription factor 7 interacting protein
chr10_-_29923893 1.80 ENST00000355867.4
supervillin
chr1_-_94147385 1.73 ENST00000260502.6
breast cancer anti-estrogen resistance 3
chr3_-_124774802 1.57 ENST00000311127.4
heart development protein with EGF-like domains 1
chr14_-_75083313 1.49 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr20_+_31823792 1.39 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPI fold containing family A, member 1
chr1_+_92632542 1.15 ENST00000409154.4
ENST00000370378.4
KIAA1107
chr4_+_76649753 1.14 ENST00000603759.1
USO1 vesicle transport factor
chr2_-_31440377 1.14 ENST00000444918.2
ENST00000403897.3
calpain 14
chr1_+_158978768 1.14 ENST00000447473.2
interferon, gamma-inducible protein 16
chr4_-_100356291 1.08 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr19_-_58485895 1.05 ENST00000314391.3
chromosome 19 open reading frame 18
chr16_+_24549014 1.05 ENST00000564314.1
ENST00000567686.1
retinoblastoma binding protein 6
chr4_-_83769996 1.04 ENST00000511338.1
SEC31 homolog A (S. cerevisiae)
chr5_+_145826867 0.92 ENST00000296702.5
ENST00000394421.2
transcription elongation regulator 1
chr6_+_15401075 0.91 ENST00000541660.1
jumonji, AT rich interactive domain 2
chr3_-_195310802 0.89 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr4_-_143226979 0.88 ENST00000514525.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr15_+_44719996 0.88 ENST00000559793.1
ENST00000558968.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_-_143227088 0.85 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr16_+_53469525 0.85 ENST00000544405.2
retinoblastoma-like 2 (p130)
chr3_-_9291063 0.83 ENST00000383836.3
SLIT-ROBO Rho GTPase activating protein 3
chr15_+_42066632 0.82 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
mitogen-activated protein kinase binding protein 1
chr4_-_87028478 0.82 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr4_+_169013666 0.81 ENST00000359299.3
annexin A10
chr3_-_12587055 0.80 ENST00000564146.3
chromosome 3 open reading frame 83
chr5_-_39270725 0.79 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr6_-_138833630 0.79 ENST00000533765.1
NHS-like 1
chr7_+_18548878 0.79 ENST00000456174.2
histone deacetylase 9
chr4_-_119759795 0.75 ENST00000419654.2
SEC24 family member D
chr14_-_36988882 0.75 ENST00000498187.2
NK2 homeobox 1
chr1_-_21377383 0.75 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr7_+_90338547 0.73 ENST00000446790.1
cyclin-dependent kinase 14
chr3_+_140660743 0.72 ENST00000453248.2
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr5_-_136649218 0.71 ENST00000510405.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr12_-_67197760 0.71 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
glutamate receptor interacting protein 1
chr4_-_76649546 0.71 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
GTPase activating protein (SH3 domain) binding protein 2
chr17_-_5321549 0.69 ENST00000572809.1
nucleoporin 88kDa
chr3_+_140660634 0.68 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr3_-_141747439 0.67 ENST00000467667.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_-_26199499 0.66 ENST00000377831.5
histone cluster 1, H3d
chr7_+_18548924 0.66 ENST00000524023.1
histone deacetylase 9
chr14_+_95078714 0.66 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr14_+_101293687 0.65 ENST00000455286.1
maternally expressed 3 (non-protein coding)
chr3_-_33759699 0.65 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
cytoplasmic linker associated protein 2
chr7_+_90339169 0.63 ENST00000436577.2
cyclin-dependent kinase 14
chr8_-_103884640 0.63 ENST00000520402.1
antizyme inhibitor 1
chr12_-_89746173 0.61 ENST00000308385.6
dual specificity phosphatase 6
chr6_-_26199471 0.61 ENST00000341023.1
histone cluster 1, H2ad
chr6_-_134639042 0.61 ENST00000461976.2
serum/glucocorticoid regulated kinase 1
chrX_-_15619076 0.60 ENST00000252519.3
angiotensin I converting enzyme 2
chr4_+_76649797 0.60 ENST00000538159.1
ENST00000514213.2
USO1 vesicle transport factor
chr15_+_44719790 0.59 ENST00000558791.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_+_36152179 0.59 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_-_75226166 0.59 ENST00000544628.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr1_+_52682052 0.58 ENST00000371591.1
zinc finger, FYVE domain containing 9
chr2_+_234600253 0.57 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr15_+_57511609 0.57 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12
chr8_+_26150628 0.57 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr12_+_104337515 0.57 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr5_-_160279207 0.52 ENST00000327245.5
ATPase, class V, type 10B
chr1_-_200379129 0.51 ENST00000367353.1
zinc finger protein 281
chr1_+_154401791 0.51 ENST00000476006.1
interleukin 6 receptor
chr2_+_65215604 0.51 ENST00000531327.1
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr17_+_44701402 0.51 ENST00000575068.1
N-ethylmaleimide-sensitive factor
chr3_-_141747950 0.50 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_+_191334212 0.49 ENST00000444317.1
ENST00000535751.1
major facilitator superfamily domain containing 6
chr15_+_44719970 0.49 ENST00000558966.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_+_121774202 0.48 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86 molecule
chr6_-_66417107 0.48 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
eyes shut homolog (Drosophila)
chr6_+_45296391 0.48 ENST00000371436.6
ENST00000576263.1
runt-related transcription factor 2
chr1_+_206557366 0.47 ENST00000414007.1
ENST00000419187.2
SLIT-ROBO Rho GTPase activating protein 2
chr15_-_43398274 0.47 ENST00000382177.2
ENST00000290650.4
ubiquitin protein ligase E3 component n-recognin 1
chr8_-_57123815 0.46 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr8_-_112248400 0.46 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
chr1_-_110155671 0.46 ENST00000351050.3
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr12_-_118628350 0.45 ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr14_-_38064198 0.44 ENST00000250448.2
forkhead box A1
chr2_+_54683419 0.44 ENST00000356805.4
spectrin, beta, non-erythrocytic 1
chr5_-_115872124 0.44 ENST00000515009.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_+_190105909 0.42 ENST00000456423.1
claudin 16
chr12_-_112123524 0.42 ENST00000327551.6
BRCA1 associated protein
chr17_+_44588877 0.42 ENST00000576629.1
leucine rich repeat containing 37, member A2
chr9_+_88556444 0.41 ENST00000376040.1
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr4_+_74347400 0.40 ENST00000226355.3
afamin
chr17_+_75181292 0.40 ENST00000431431.2
SEC14-like 1 (S. cerevisiae)
chr2_+_119699864 0.39 ENST00000541757.1
ENST00000412481.1
macrophage receptor with collagenous structure
chr16_+_53133070 0.39 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr12_-_125052010 0.38 ENST00000458234.1
nuclear receptor corepressor 2
chr5_-_115872142 0.38 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_118797475 0.37 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr5_-_134735568 0.37 ENST00000510038.1
ENST00000304332.4
H2A histone family, member Y
chr11_-_95522907 0.36 ENST00000358780.5
ENST00000542135.1
family with sequence similarity 76, member B
chr11_-_95523500 0.35 ENST00000540054.1
family with sequence similarity 76, member B
chr7_+_138915102 0.35 ENST00000486663.1
ubinuclein 2
chr17_-_60885645 0.35 ENST00000544856.2
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chrX_+_107288280 0.34 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr21_+_48055527 0.33 ENST00000397638.2
ENST00000458387.2
ENST00000451211.2
ENST00000291705.6
ENST00000397637.1
ENST00000334494.4
ENST00000397628.1
ENST00000440086.1
protein arginine methyltransferase 2
chr12_-_89746264 0.33 ENST00000548755.1
dual specificity phosphatase 6
chr2_+_119699742 0.32 ENST00000327097.4
macrophage receptor with collagenous structure
chr9_-_27005686 0.32 ENST00000380055.5
leucine rich repeat containing 19
chr17_-_60885700 0.31 ENST00000583600.1
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr3_+_130569429 0.31 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr7_+_107224364 0.30 ENST00000491150.1
B-cell receptor-associated protein 29
chr3_-_32544900 0.30 ENST00000205636.3
CKLF-like MARVEL transmembrane domain containing 6
chr17_+_71228843 0.30 ENST00000582391.1
chromosome 17 open reading frame 80
chr16_+_1728257 0.30 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
hematological and neurological expressed 1-like
chr17_-_60885659 0.29 ENST00000311269.5
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr12_-_49581152 0.29 ENST00000550811.1
tubulin, alpha 1a
chr11_-_16419067 0.29 ENST00000533411.1
SRY (sex determining region Y)-box 6
chr5_+_140079919 0.28 ENST00000274712.3
zinc finger, matrin-type 2
chr17_+_71228537 0.28 ENST00000577615.1
ENST00000585109.1
chromosome 17 open reading frame 80
chr10_-_25304889 0.27 ENST00000483339.2
enkurin, TRPC channel interacting protein
chr3_-_141747459 0.27 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr14_+_57671888 0.26 ENST00000391612.1
AL391152.1
chr3_-_130465604 0.26 ENST00000356763.3
phosphoinositide-3-kinase, regulatory subunit 4
chr6_-_41039567 0.26 ENST00000468811.1
O-acyl-ADP-ribose deacylase 1
chr3_-_194188956 0.26 ENST00000256031.4
ENST00000446356.1
ATPase type 13A3
chr4_-_36245561 0.26 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_83765613 0.26 ENST00000503937.1
SEC31 homolog A (S. cerevisiae)
chr17_+_57807062 0.25 ENST00000587259.1
vacuole membrane protein 1
chr8_-_122653630 0.25 ENST00000303924.4
hyaluronan synthase 2
chr14_+_23709555 0.25 ENST00000430154.2
chromosome 14 open reading frame 164
chr1_+_84630574 0.25 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_53601000 0.24 ENST00000338737.4
ENST00000549086.2
integrin, beta 7
chr17_+_71228793 0.23 ENST00000426147.2
chromosome 17 open reading frame 80
chr20_+_58203664 0.23 ENST00000541461.1
phosphatase and actin regulator 3
chr15_+_43477580 0.23 ENST00000356633.5
cyclin D-type binding-protein 1
chr12_-_10324716 0.23 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr17_+_67759813 0.22 ENST00000587241.1
AC003051.1
chr2_+_179184955 0.22 ENST00000315022.2
oxysterol binding protein-like 6
chr3_+_40518599 0.21 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
zinc finger protein 619
chr6_+_34204642 0.21 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr11_-_95522639 0.21 ENST00000536839.1
family with sequence similarity 76, member B
chr5_+_59783540 0.21 ENST00000515734.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr4_-_186578674 0.20 ENST00000438278.1
sorbin and SH3 domain containing 2
chr1_+_180601139 0.20 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr6_-_170893268 0.20 ENST00000538195.1
programmed cell death 2
chr5_+_140743859 0.20 ENST00000518069.1
protocadherin gamma subfamily A, 5
chr5_+_36152163 0.20 ENST00000274255.6
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_-_99030395 0.20 ENST00000355366.5
ENST00000371027.1
Rho GTPase activating protein 19
chr4_+_109571800 0.20 ENST00000512478.2
oligosaccharyltransferase complex subunit (non-catalytic)
chr13_-_81801115 0.19 ENST00000567258.1
long intergenic non-protein coding RNA 564
chr7_-_82792215 0.19 ENST00000333891.9
ENST00000423517.2
piccolo presynaptic cytomatrix protein
chr11_+_128563652 0.19 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr5_+_36152091 0.19 ENST00000274254.5
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_-_111649074 0.19 ENST00000534218.1
RP11-108O10.2
chr4_-_100356551 0.18 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr5_+_140762268 0.18 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr12_-_53601055 0.18 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
integrin, beta 7
chr16_+_68119247 0.18 ENST00000575270.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr15_+_66874502 0.18 ENST00000558797.1
HCG2003567; Uncharacterized protein
chr6_-_154751629 0.17 ENST00000424998.1
CNKSR family member 3
chr2_+_183582774 0.17 ENST00000537515.1
DnaJ (Hsp40) homolog, subfamily C, member 10
chr14_-_78083112 0.16 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr6_-_134639180 0.16 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr11_+_18433840 0.16 ENST00000541669.1
ENST00000280704.4
lactate dehydrogenase C
chr3_-_47934234 0.16 ENST00000420772.2
microtubule-associated protein 4
chr7_-_140482926 0.16 ENST00000496384.2
v-raf murine sarcoma viral oncogene homolog B
chr6_+_12007963 0.15 ENST00000607445.1
RP11-456H18.2
chr18_+_616672 0.15 ENST00000338387.7
clusterin-like 1 (retinal)
chr5_+_147691979 0.15 ENST00000274565.4
serine peptidase inhibitor, Kazal type 7 (putative)
chrM_+_7586 0.15 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr2_+_44001172 0.15 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
dynein, cytoplasmic 2, light intermediate chain 1
chr11_-_111649015 0.15 ENST00000529841.1
RP11-108O10.2
chr15_-_75748143 0.15 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3 transcription regulator family member A
chr1_-_152131703 0.15 ENST00000316073.3
repetin
chr1_+_183774285 0.14 ENST00000539189.1
ral guanine nucleotide dissociation stimulator-like 1
chr7_+_30589829 0.14 ENST00000579437.1
RP4-777O23.1
chr13_+_20268547 0.14 ENST00000601204.1
AL354808.2
chr14_-_57197224 0.14 ENST00000554597.1
ENST00000556696.1
Uncharacterized protein
chr19_-_6393216 0.14 ENST00000595047.1
general transcription factor IIF, polypeptide 1, 74kDa
chr5_+_137722255 0.14 ENST00000542866.1
lysine (K)-specific demethylase 3B
chr15_-_75748115 0.14 ENST00000360439.4
SIN3 transcription regulator family member A
chr3_+_111393501 0.13 ENST00000393934.3
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_+_107738240 0.13 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr2_+_185463093 0.13 ENST00000302277.6
zinc finger protein 804A
chr5_+_137203465 0.13 ENST00000239926.4
myotilin
chr1_-_232651312 0.13 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr7_-_55620433 0.13 ENST00000418904.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr14_+_62584197 0.13 ENST00000334389.4
long intergenic non-protein coding RNA 643
chr12_+_122241928 0.13 ENST00000604567.1
ENST00000542440.1
SET domain containing 1B
chr3_+_138340049 0.12 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr11_-_40315640 0.12 ENST00000278198.2
leucine rich repeat containing 4C
chr12_+_122688090 0.11 ENST00000324189.4
ENST00000546192.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr7_-_115799942 0.11 ENST00000484212.1
transcription factor EC
chr4_+_95128996 0.11 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_-_154600421 0.11 ENST00000368471.3
ENST00000292205.5
adenosine deaminase, RNA-specific
chr12_-_91546926 0.11 ENST00000550758.1
decorin

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0060166 olfactory pit development(GO:0060166)
0.5 1.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.5 1.4 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.5 2.3 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.4 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.3 1.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 2.8 GO:0048706 embryonic skeletal system development(GO:0048706)
0.2 0.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 1.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 0.6 GO:0031247 actin rod assembly(GO:0031247)
0.2 0.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.5 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 0.6 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.4 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.4 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.1 0.5 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.4 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 1.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 1.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.6 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.5 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 3.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 2.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.8 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 1.4 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.5 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.5 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 1.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 2.0 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 1.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.7 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.5 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 2.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.5 GO:0060736 prostate gland growth(GO:0060736)
0.0 1.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 2.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.0 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 1.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.1 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.0 GO:0072505 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781) divalent inorganic anion homeostasis(GO:0072505)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:1990032 parallel fiber(GO:1990032)
0.6 3.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.8 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 2.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.4 GO:0001740 Barr body(GO:0001740)
0.0 0.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 1.6 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.4 3.5 GO:0004111 creatine kinase activity(GO:0004111)
0.3 2.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.3 1.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 1.7 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 0.5 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 2.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.4 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.5 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 3.6 GO:0030332 cyclin binding(GO:0030332)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 1.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.7 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 3.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 2.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.4 PID FOXO PATHWAY FoxO family signaling
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 2.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling