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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ALX3

Z-value: 0.69

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Transcription factors associated with ALX3

Gene Symbol Gene ID Gene Info
ALX3
ENSG00000156150.6 ALX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX3hg19_v2_chr1_-_110613276_1106133220.116.4e-01Click!

Activity profile of ALX3 motif

Sorted Z-values of ALX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_105845674 4.28 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr10_-_105845536 3.64 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr11_-_13011081 2.90 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
LINC00958
long intergenic non-protein coding RNA 958
chr3_-_151034734 2.78 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chrX_+_43515467 2.67 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr17_+_1674982 2.47 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr18_+_29027696 2.43 ENST00000257189.4
DSG3
desmoglein 3
chr17_-_7167279 2.34 ENST00000571932.2
CLDN7
claudin 7
chr11_+_5710919 2.28 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr3_+_195447738 2.08 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr11_-_327537 1.96 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr15_+_101417919 1.77 ENST00000561338.1
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr13_-_86373536 1.65 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr10_-_28571015 1.50 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_+_102953608 1.43 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr19_+_49199209 1.36 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr5_+_150639360 1.32 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr4_-_74486217 1.32 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr11_+_71900703 1.30 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr5_+_66300464 1.29 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr2_+_210517895 1.26 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr2_+_210518057 1.25 ENST00000452717.1
MAP2
microtubule-associated protein 2
chr19_-_36001113 1.24 ENST00000434389.1
DMKN
dermokine
chr11_+_71900572 1.22 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr6_-_138833630 1.18 ENST00000533765.1
NHSL1
NHS-like 1
chrX_+_135618258 1.15 ENST00000440515.1
ENST00000456412.1
VGLL1
vestigial like 1 (Drosophila)
chr15_+_94899183 1.13 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr3_-_160823040 1.12 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr4_-_74486347 1.11 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr5_+_66300446 1.11 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_+_130339710 1.11 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr4_-_74486109 1.06 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr10_+_24755416 1.05 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr5_+_81575281 0.97 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr7_+_150020363 0.97 ENST00000359623.4
ENST00000493307.1
LRRC61
leucine rich repeat containing 61
chr14_-_67878917 0.95 ENST00000216446.4
PLEK2
pleckstrin 2
chr11_-_128894053 0.94 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr7_+_150020329 0.93 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr1_+_160370344 0.92 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr3_-_160823158 0.90 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_81771806 0.90 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr12_+_104337515 0.88 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr3_+_28390637 0.87 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr9_+_124329336 0.85 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr4_+_144312659 0.82 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr8_-_116504448 0.81 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr3_+_121774202 0.80 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr4_+_37455536 0.78 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr16_+_31724552 0.77 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr2_+_191221240 0.76 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr20_-_50722183 0.75 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr6_-_32095968 0.75 ENST00000375203.3
ENST00000375201.4
ATF6B
activating transcription factor 6 beta
chr8_-_29605625 0.74 ENST00000506121.3
LINC00589
long intergenic non-protein coding RNA 589
chr4_+_26324474 0.74 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr12_-_10022735 0.69 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr9_+_470288 0.65 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr12_+_66582919 0.62 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chr6_+_64345698 0.60 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHF3
PHD finger protein 3
chr15_+_44719996 0.59 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_-_48130707 0.59 ENST00000360240.6
ENST00000383737.4
MAP4
microtubule-associated protein 4
chr11_+_35201826 0.59 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr16_-_28608424 0.59 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_-_24306768 0.58 ENST00000374453.3
ENST00000453840.3
SRSF10
serine/arginine-rich splicing factor 10
chr2_-_74618907 0.58 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr4_-_85654615 0.57 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr12_-_22063787 0.57 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr17_+_35851570 0.56 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr16_-_28634874 0.55 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr10_+_90484301 0.52 ENST00000404190.1
LIPK
lipase, family member K
chr1_+_152784447 0.52 ENST00000360090.3
LCE1B
late cornified envelope 1B
chr6_+_44355257 0.51 ENST00000371477.3
CDC5L
cell division cycle 5-like
chrX_-_102510126 0.50 ENST00000372685.3
TCEAL8
transcription elongation factor A (SII)-like 8
chr16_+_31724618 0.50 ENST00000530881.1
ENST00000529515.1
ZNF720
zinc finger protein 720
chr3_-_141747950 0.50 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr19_-_14064114 0.49 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr6_+_26440700 0.49 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr8_-_93978216 0.48 ENST00000517751.1
ENST00000524107.1
TRIQK
triple QxxK/R motif containing
chr14_+_57671888 0.48 ENST00000391612.1
AL391152.1
AL391152.1
chr3_-_141719195 0.48 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_-_185275104 0.48 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr12_+_56435637 0.46 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr3_+_139063372 0.46 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr2_+_68961934 0.46 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chrX_+_3189861 0.46 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr12_-_112123524 0.46 ENST00000327551.6
BRAP
BRCA1 associated protein
chr4_-_103749205 0.45 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_24306835 0.45 ENST00000484146.2
SRSF10
serine/arginine-rich splicing factor 10
chr1_-_54411255 0.44 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr11_-_107729887 0.43 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr9_-_5339873 0.42 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr2_+_68961905 0.42 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr13_-_46742630 0.41 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_68962014 0.40 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr4_-_25865159 0.40 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr13_+_76413852 0.40 ENST00000533809.2
LMO7
LIM domain 7
chr5_-_41794313 0.40 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr14_+_32798462 0.40 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr5_-_94890648 0.40 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
TTC37
tetratricopeptide repeat domain 37
chr7_-_92777606 0.38 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr1_+_117544366 0.37 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr8_-_93978357 0.37 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr10_-_90611566 0.37 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr10_-_95241951 0.36 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chrX_+_107288280 0.36 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr11_-_107729504 0.36 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr6_+_37897735 0.35 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr15_+_44719790 0.35 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr16_-_28621298 0.35 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr3_+_183853052 0.34 ENST00000273783.3
ENST00000432569.1
ENST00000444495.1
EIF2B5
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
chr6_-_36515177 0.33 ENST00000229812.7
STK38
serine/threonine kinase 38
chr7_-_44580861 0.33 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1
NPC1-like 1
chr13_+_40229764 0.33 ENST00000416691.1
ENST00000422759.2
ENST00000455146.3
COG6
component of oligomeric golgi complex 6
chr12_-_74686314 0.32 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr7_-_87856303 0.32 ENST00000394641.3
SRI
sorcin
chr7_+_107224364 0.32 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr12_+_122688090 0.31 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr3_+_186692745 0.31 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr15_+_75970672 0.31 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr7_+_133812052 0.30 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr1_-_24306798 0.30 ENST00000374452.5
ENST00000492112.2
ENST00000343255.5
ENST00000344989.6
SRSF10
serine/arginine-rich splicing factor 10
chr17_+_40610862 0.30 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr16_-_28621312 0.30 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_+_80584903 0.29 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr4_+_26344754 0.29 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_103749313 0.29 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr11_-_107729287 0.29 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr17_+_18086392 0.29 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr4_+_86525299 0.28 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr6_+_158733692 0.28 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr8_-_93978333 0.27 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr4_-_103749179 0.27 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_+_105235572 0.26 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr5_-_159846399 0.26 ENST00000297151.4
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr10_-_95242044 0.26 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr2_-_169887827 0.26 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr17_+_67759813 0.25 ENST00000587241.1
AC003051.1
AC003051.1
chr4_+_142142035 0.25 ENST00000262990.4
ENST00000512809.1
ENST00000503649.1
ENST00000512738.1
ENST00000421169.2
ZNF330
zinc finger protein 330
chr7_-_87856280 0.24 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr1_+_207226574 0.24 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr7_-_150020578 0.24 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr7_+_37723336 0.23 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chrX_-_77225135 0.22 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr9_+_95709733 0.21 ENST00000375482.3
FGD3
FYVE, RhoGEF and PH domain containing 3
chr2_+_103089756 0.21 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr1_-_202897724 0.21 ENST00000435533.3
ENST00000367258.1
KLHL12
kelch-like family member 12
chr1_-_17766198 0.21 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr16_-_28608364 0.21 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr11_-_62323702 0.20 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr12_+_64798826 0.20 ENST00000540203.1
XPOT
exportin, tRNA
chr7_+_37723450 0.20 ENST00000447769.1
GPR141
G protein-coupled receptor 141
chr16_-_28621353 0.20 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_+_107288239 0.20 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr4_+_71859156 0.19 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr16_+_53133070 0.19 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_-_43965937 0.19 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
URGCP
upregulator of cell proliferation
chr10_+_35894338 0.19 ENST00000321660.1
GJD4
gap junction protein, delta 4, 40.1kDa
chr1_+_144989309 0.19 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr4_-_103749105 0.18 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr18_-_53303123 0.17 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr9_-_116065551 0.17 ENST00000297894.5
RNF183
ring finger protein 183
chr8_+_29605860 0.17 ENST00000517491.1
AC145110.1
AC145110.1
chr9_+_117904097 0.16 ENST00000374016.1
DEC1
deleted in esophageal cancer 1
chr3_-_52719546 0.16 ENST00000439181.1
ENST00000449505.1
PBRM1
polybromo 1
chr4_-_36245561 0.16 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr16_+_31885079 0.16 ENST00000300870.10
ENST00000394846.3
ZNF267
zinc finger protein 267
chr12_-_118797475 0.16 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr13_+_111748183 0.16 ENST00000422994.1
LINC00368
long intergenic non-protein coding RNA 368
chr15_+_44719970 0.16 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr18_-_67624160 0.15 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr8_+_29605841 0.15 ENST00000523123.1
AC145110.1
AC145110.1
chr7_-_2883650 0.15 ENST00000544127.1
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr9_-_99540328 0.15 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr12_+_26164645 0.14 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr3_+_40518599 0.14 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr17_-_12920994 0.14 ENST00000609101.1
ELAC2
elaC ribonuclease Z 2
chr3_+_185431080 0.14 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr15_-_98417780 0.14 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr5_+_140762268 0.14 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr3_+_43020773 0.13 ENST00000488863.1
FAM198A
family with sequence similarity 198, member A
chr10_+_70661014 0.13 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr11_+_46193466 0.13 ENST00000533793.1
RP11-702F3.3
RP11-702F3.3
chr4_+_86699834 0.13 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr5_+_176811431 0.13 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr1_+_162336686 0.13 ENST00000420220.1
C1orf226
chromosome 1 open reading frame 226
chr15_+_58724184 0.13 ENST00000433326.2
LIPC
lipase, hepatic
chr1_-_207226313 0.12 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr22_+_42834029 0.12 ENST00000428765.1
CTA-126B4.7
CTA-126B4.7
chr4_+_5526883 0.12 ENST00000195455.2
C4orf6
chromosome 4 open reading frame 6
chr11_-_62521614 0.12 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr14_+_39736582 0.12 ENST00000556148.1
ENST00000348007.3
CTAGE5
CTAGE family, member 5
chr1_-_150669604 0.12 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr7_-_140482926 0.12 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr4_+_5527117 0.12 ENST00000505296.1
C4orf6
chromosome 4 open reading frame 6
chr3_+_138340049 0.11 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr2_+_217524323 0.11 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr6_+_55192267 0.11 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chrX_+_107288197 0.11 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr19_-_44388116 0.11 ENST00000587539.1
ZNF404
zinc finger protein 404
chr10_+_6821545 0.10 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr3_-_150421752 0.10 ENST00000498386.1
FAM194A
family with sequence similarity 194, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4 1.8 GO:0060166 olfactory pit development(GO:0060166)
0.3 0.9 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 0.9 GO:0031247 actin rod assembly(GO:0031247)
0.3 1.6 GO:0060005 vestibular reflex(GO:0060005)
0.3 0.8 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 1.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 7.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 1.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 0.9 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 2.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 1.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.0 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.5 GO:1990637 response to prolactin(GO:1990637)
0.1 2.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.6 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 2.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 1.4 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 2.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.6 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.2 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.6 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.3 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 2.1 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.6 GO:0035973 aggrephagy(GO:0035973)
0.0 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 1.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.8 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 1.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 1.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 2.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 2.5 GO:0070268 cornification(GO:0070268)
0.0 1.3 GO:0070206 protein trimerization(GO:0070206)
0.0 0.4 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.5 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 2.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 0.9 GO:1990032 parallel fiber(GO:1990032)
0.3 7.9 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.1 0.6 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 2.5 GO:0043203 axon hillock(GO:0043203)
0.1 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.4 GO:0055087 Ski complex(GO:0055087)
0.1 2.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0044326 dendritic spine neck(GO:0044326)
0.1 1.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.4 GO:0030057 desmosome(GO:0030057)
0.1 2.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0061714 folic acid receptor activity(GO:0061714)
0.5 2.0 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.5 1.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 2.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.3 2.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.3 GO:0050733 RS domain binding(GO:0050733)
0.2 0.8 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 1.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 2.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.8 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.9 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 2.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.0 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.6 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 1.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.5 GO:0004860 protein kinase inhibitor activity(GO:0004860) protein kinase regulator activity(GO:0019887)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 2.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.3 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 7.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling