Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for ATF6

Z-value: 1.02

Motif logo

logo of

Transcription factors associated with ATF6

Gene Symbol Gene ID Gene Info
ATF6
ENSG00000118217.5 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF6hg19_v2_chr1_+_161736072_1617360930.793.0e-05Click!

Activity profile of ATF6 motif

Sorted Z-values of ATF6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_100914781 6.04 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
ARMCX2
armadillo repeat containing, X-linked 2
chr5_-_132299290 4.24 ENST00000378595.3
AFF4
AF4/FMR2 family, member 4
chr6_+_116692102 3.93 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr19_-_46916805 3.54 ENST00000307522.3
CCDC8
coiled-coil domain containing 8
chr4_-_187647773 2.66 ENST00000509647.1
FAT1
FAT atypical cadherin 1
chrX_+_102862834 2.49 ENST00000372627.5
ENST00000243286.3
TCEAL3
transcription elongation factor A (SII)-like 3
chr21_+_38445539 2.47 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr10_-_27444143 2.46 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr1_-_113498616 2.40 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr11_-_119599794 2.40 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr19_+_16186903 2.32 ENST00000588507.1
TPM4
tropomyosin 4
chr19_+_38810447 2.29 ENST00000263372.3
KCNK6
potassium channel, subfamily K, member 6
chr8_+_94929077 2.28 ENST00000297598.4
ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_+_94929273 2.27 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_+_94929168 2.25 ENST00000518107.1
ENST00000396200.3
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr19_-_9811347 2.23 ENST00000585964.1
ENST00000457674.2
ENST00000590544.1
ZNF812
zinc finger protein 812
chr2_+_219745020 2.23 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr1_-_28503693 2.21 ENST00000373857.3
PTAFR
platelet-activating factor receptor
chr10_-_120840309 2.21 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr8_-_75233563 2.21 ENST00000342232.4
JPH1
junctophilin 1
chr8_+_94929110 2.13 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr22_-_44258360 2.13 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr2_-_242255060 2.08 ENST00000413241.1
ENST00000423693.1
ENST00000428482.1
HDLBP
high density lipoprotein binding protein
chr9_+_124461603 2.05 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr1_-_113498943 2.04 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr12_+_1100449 2.01 ENST00000360905.4
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr6_+_32937083 1.99 ENST00000456339.1
BRD2
bromodomain containing 2
chr4_-_99850243 1.92 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr4_-_169931231 1.83 ENST00000504561.1
CBR4
carbonyl reductase 4
chr12_-_123380610 1.80 ENST00000535765.1
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr9_+_112542572 1.75 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr12_+_1100423 1.74 ENST00000592048.1
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr12_+_1100370 1.73 ENST00000543086.3
ENST00000546231.2
ENST00000397203.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr3_+_50284321 1.73 ENST00000451956.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr3_-_197024965 1.70 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr12_-_120662499 1.70 ENST00000552550.1
PXN
paxillin
chr20_+_32951070 1.68 ENST00000535650.1
ENST00000262650.6
ITCH
itchy E3 ubiquitin protein ligase
chr4_+_85504075 1.66 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr2_-_242255117 1.65 ENST00000420451.1
ENST00000417540.1
ENST00000310931.4
HDLBP
high density lipoprotein binding protein
chr1_+_40506255 1.61 ENST00000421589.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_128841503 1.60 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr11_+_65554493 1.60 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr6_-_32145861 1.60 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr20_+_33292507 1.55 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr17_+_66511540 1.52 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr20_-_44420507 1.51 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr1_+_154193325 1.46 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr5_-_131563474 1.38 ENST00000417528.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr17_-_17875688 1.37 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr13_-_36920615 1.36 ENST00000494062.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr11_-_117102768 1.36 ENST00000532301.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr11_-_35547151 1.36 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr19_+_19516561 1.34 ENST00000457895.2
GATAD2A
GATA zinc finger domain containing 2A
chr19_+_16187085 1.34 ENST00000300933.4
TPM4
tropomyosin 4
chr11_-_129149197 1.33 ENST00000525234.1
ARHGAP32
Rho GTPase activating protein 32
chr1_-_50889155 1.32 ENST00000404795.3
DMRTA2
DMRT-like family A2
chr6_-_86353510 1.32 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_+_66511224 1.31 ENST00000588178.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_+_75311019 1.31 ENST00000502307.1
AREG
amphiregulin
chr13_-_49107205 1.31 ENST00000544904.1
ENST00000430805.2
ENST00000544492.1
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr7_-_38969150 1.29 ENST00000418457.2
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr5_-_171881491 1.29 ENST00000311601.5
SH3PXD2B
SH3 and PX domains 2B
chr2_-_98612379 1.28 ENST00000425805.2
TMEM131
transmembrane protein 131
chr3_+_100211412 1.27 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A
transmembrane protein 45A
chr12_+_46777450 1.26 ENST00000551503.1
RP11-96H19.1
RP11-96H19.1
chr13_-_36920420 1.25 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr21_-_46238034 1.24 ENST00000332859.6
SUMO3
small ubiquitin-like modifier 3
chr1_+_87170577 1.23 ENST00000482504.1
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr3_-_197024394 1.23 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr13_+_114238997 1.22 ENST00000538138.1
ENST00000375370.5
TFDP1
transcription factor Dp-1
chr5_+_133984462 1.21 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr11_-_59383617 1.21 ENST00000263847.1
OSBP
oxysterol binding protein
chr5_-_131562935 1.20 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr7_+_44646177 1.20 ENST00000443864.2
ENST00000447398.1
ENST00000449767.1
ENST00000419661.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr4_-_169931393 1.20 ENST00000504480.1
ENST00000306193.3
CBR4
carbonyl reductase 4
chr2_+_223726281 1.20 ENST00000413316.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr2_-_98612350 1.18 ENST00000186436.5
TMEM131
transmembrane protein 131
chr11_-_118927816 1.17 ENST00000534233.1
ENST00000532752.1
ENST00000525859.1
ENST00000404233.3
ENST00000532421.1
ENST00000543287.1
ENST00000527310.2
ENST00000529972.1
HYOU1
hypoxia up-regulated 1
chr11_-_118927735 1.13 ENST00000526656.1
HYOU1
hypoxia up-regulated 1
chr12_-_76953513 1.13 ENST00000547540.1
OSBPL8
oxysterol binding protein-like 8
chr4_+_75310851 1.12 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr1_-_152009460 1.11 ENST00000271638.2
S100A11
S100 calcium binding protein A11
chr3_+_184032419 1.11 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_-_118927561 1.11 ENST00000530473.1
HYOU1
hypoxia up-regulated 1
chr2_+_242254679 1.10 ENST00000428282.1
ENST00000360051.3
SEPT2
septin 2
chr5_+_65440032 1.09 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr3_+_50654550 1.09 ENST00000430409.1
ENST00000357955.2
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr3_+_44771088 1.09 ENST00000396048.2
ZNF501
zinc finger protein 501
chr11_-_118927880 1.08 ENST00000527038.2
HYOU1
hypoxia up-regulated 1
chr12_-_76953573 1.08 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
OSBPL8
oxysterol binding protein-like 8
chr2_+_242254753 1.07 ENST00000428524.1
ENST00000445030.1
ENST00000407017.1
SEPT2
septin 2
chr1_+_222791417 1.06 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3
melanoma inhibitory activity family, member 3
chr18_-_46987000 1.05 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr1_-_208417620 1.05 ENST00000367033.3
PLXNA2
plexin A2
chr7_+_128379449 1.05 ENST00000479257.1
CALU
calumenin
chr5_-_132299313 1.05 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr20_-_34638841 1.04 ENST00000565493.1
LINC00657
long intergenic non-protein coding RNA 657
chr14_-_93799360 1.02 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTBD7
BTB (POZ) domain containing 7
chr6_-_151773232 1.02 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr13_-_49107303 1.01 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr3_-_121468513 1.01 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr1_+_19970657 1.01 ENST00000375136.3
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr21_-_46237959 1.01 ENST00000397898.3
ENST00000411651.2
SUMO3
small ubiquitin-like modifier 3
chr1_-_32169920 1.01 ENST00000373672.3
ENST00000373668.3
COL16A1
collagen, type XVI, alpha 1
chrX_-_128977875 1.01 ENST00000406492.2
ZDHHC9
zinc finger, DHHC-type containing 9
chr14_+_68086515 1.00 ENST00000261783.3
ARG2
arginase 2
chr9_+_133454943 0.99 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr13_-_45915221 0.98 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1
tumor protein, translationally-controlled 1
chr6_-_86352982 0.97 ENST00000369622.3
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr13_-_36920872 0.97 ENST00000451493.1
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr3_+_183415558 0.95 ENST00000305135.5
YEATS2
YEATS domain containing 2
chr5_+_78532003 0.95 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr1_-_226187013 0.95 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr15_+_96869165 0.94 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_+_98656693 0.93 ENST00000519934.1
MTDH
metadherin
chr5_-_175965008 0.92 ENST00000537487.1
RNF44
ring finger protein 44
chr1_+_19970797 0.91 ENST00000548815.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr16_+_53164833 0.91 ENST00000564845.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_-_78148324 0.91 ENST00000370801.3
ENST00000433749.1
ZZZ3
zinc finger, ZZ-type containing 3
chr7_-_27169801 0.89 ENST00000511914.1
HOXA4
homeobox A4
chr1_-_1822495 0.89 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr4_-_119757239 0.89 ENST00000280551.6
SEC24D
SEC24 family member D
chr4_+_128982430 0.88 ENST00000512292.1
ENST00000508819.1
LARP1B
La ribonucleoprotein domain family, member 1B
chr4_+_128982490 0.87 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
LARP1B
La ribonucleoprotein domain family, member 1B
chr11_-_35547572 0.86 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr16_-_70719925 0.86 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr3_+_184032283 0.86 ENST00000346169.2
ENST00000414031.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_-_35547277 0.85 ENST00000527605.1
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr7_+_44646162 0.85 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr3_-_139108475 0.85 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr2_+_242254507 0.85 ENST00000391973.2
SEPT2
septin 2
chr22_-_44258280 0.85 ENST00000540422.1
SULT4A1
sulfotransferase family 4A, member 1
chr22_-_39096981 0.84 ENST00000427389.1
JOSD1
Josephin domain containing 1
chr2_-_242254595 0.84 ENST00000441124.1
ENST00000391976.2
HDLBP
high density lipoprotein binding protein
chr6_+_87865262 0.84 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr11_+_68228186 0.83 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3
protein phosphatase 6, regulatory subunit 3
chr16_+_68298466 0.83 ENST00000568088.1
ENST00000564708.1
SLC7A6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr20_+_62526467 0.83 ENST00000369911.2
ENST00000360864.4
DNAJC5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr3_+_133292574 0.82 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr11_+_20409227 0.82 ENST00000437750.2
PRMT3
protein arginine methyltransferase 3
chr20_+_32951041 0.82 ENST00000374864.4
ITCH
itchy E3 ubiquitin protein ligase
chr8_-_41909496 0.80 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A
K(lysine) acetyltransferase 6A
chr20_+_39657454 0.80 ENST00000361337.2
TOP1
topoisomerase (DNA) I
chr20_+_35090150 0.79 ENST00000340491.4
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr12_+_1100710 0.79 ENST00000589132.1
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr3_-_33759541 0.78 ENST00000468888.2
CLASP2
cytoplasmic linker associated protein 2
chr3_-_128840604 0.78 ENST00000476465.1
ENST00000315150.5
ENST00000393304.1
ENST00000393308.1
ENST00000393307.1
ENST00000393305.1
RAB43
RAB43, member RAS oncogene family
chr22_-_39096925 0.78 ENST00000456626.1
ENST00000412832.1
JOSD1
Josephin domain containing 1
chr6_+_151773583 0.77 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr15_+_67420441 0.77 ENST00000558894.1
SMAD3
SMAD family member 3
chr8_-_17104099 0.77 ENST00000524358.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr3_+_170075436 0.76 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr16_-_66959429 0.76 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr14_+_105190514 0.76 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr3_-_121468602 0.76 ENST00000340645.5
GOLGB1
golgin B1
chr16_+_69373471 0.75 ENST00000569637.2
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr6_+_32936353 0.75 ENST00000374825.4
BRD2
bromodomain containing 2
chr12_-_76953453 0.75 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr12_-_113909877 0.75 ENST00000261731.3
LHX5
LIM homeobox 5
chrX_-_101397433 0.75 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr1_+_40505891 0.74 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr14_+_65016620 0.74 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr14_-_81687575 0.74 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr3_+_158519654 0.74 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr1_-_185286461 0.73 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chr1_-_94050668 0.71 ENST00000539242.1
BCAR3
breast cancer anti-estrogen resistance 3
chr6_-_86352642 0.70 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr20_-_33413416 0.70 ENST00000359003.2
NCOA6
nuclear receptor coactivator 6
chr6_+_44355257 0.70 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr2_-_242211359 0.69 ENST00000444092.1
HDLBP
high density lipoprotein binding protein
chr2_-_242212227 0.69 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP
high density lipoprotein binding protein
chr20_+_34359905 0.68 ENST00000374012.3
ENST00000439301.1
ENST00000339089.6
ENST00000374000.4
PHF20
PHD finger protein 20
chr1_-_78149041 0.68 ENST00000414381.1
ENST00000370798.1
ZZZ3
zinc finger, ZZ-type containing 3
chr17_-_4643114 0.68 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr15_-_43785274 0.68 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chrX_+_100663243 0.68 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr10_+_121410882 0.68 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr5_+_60628074 0.67 ENST00000252744.5
ZSWIM6
zinc finger, SWIM-type containing 6
chr12_-_49412525 0.67 ENST00000551121.1
ENST00000552212.1
ENST00000548605.1
ENST00000548950.1
ENST00000547125.1
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr11_+_119076745 0.65 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr4_-_4543700 0.65 ENST00000505286.1
ENST00000306200.2
STX18
syntaxin 18
chr7_+_44646218 0.65 ENST00000444676.1
ENST00000222673.5
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr4_-_24914576 0.64 ENST00000502801.1
ENST00000428116.2
CCDC149
coiled-coil domain containing 149
chr9_-_131038266 0.64 ENST00000490628.1
ENST00000421699.2
ENST00000450617.1
GOLGA2
golgin A2
chr4_-_24914508 0.64 ENST00000504487.1
CCDC149
coiled-coil domain containing 149
chr19_+_49375649 0.64 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr1_-_32169761 0.64 ENST00000271069.6
COL16A1
collagen, type XVI, alpha 1
chr11_+_18720316 0.63 ENST00000280734.2
TMEM86A
transmembrane protein 86A
chr12_+_72148614 0.63 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr7_+_128379346 0.63 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr15_-_74988281 0.63 ENST00000566828.1
ENST00000563009.1
ENST00000568176.1
ENST00000566243.1
ENST00000566219.1
ENST00000426797.3
ENST00000566119.1
ENST00000315127.4
EDC3
enhancer of mRNA decapping 3
chr3_-_139108463 0.63 ENST00000512242.1
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr11_+_66886717 0.62 ENST00000398645.2
KDM2A
lysine (K)-specific demethylase 2A
chr9_-_131038214 0.61 ENST00000609374.1
GOLGA2
golgin A2
chr5_+_34656529 0.61 ENST00000513974.1
ENST00000512629.1
RAI14
retinoic acid induced 14
chr9_+_114393581 0.61 ENST00000313525.3
DNAJC25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr9_-_124855885 0.61 ENST00000321582.5
ENST00000373776.3
TTLL11
tubulin tyrosine ligase-like family, member 11
chr19_-_15442701 0.61 ENST00000594841.1
ENST00000601941.1
BRD4
bromodomain containing 4
chr15_-_82641706 0.60 ENST00000439287.4
GOLGA6L10
golgin A6 family-like 10
chr10_+_27793257 0.60 ENST00000375802.3
RAB18
RAB18, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
1.1 4.5 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
1.0 1.0 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.9 3.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.7 2.2 GO:1904303 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.7 2.2 GO:0002188 translation reinitiation(GO:0002188)
0.6 1.8 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.5 2.5 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.5 8.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.5 2.7 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.4 2.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 1.6 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.4 1.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.3 1.2 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.3 2.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.3 2.9 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.3 3.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 0.8 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 0.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 6.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 3.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.2 2.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.2 0.9 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.9 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 3.0 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.2 0.9 GO:1990637 response to prolactin(GO:1990637)
0.2 0.6 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.2 1.5 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 4.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.2 1.0 GO:0008050 female courtship behavior(GO:0008050)
0.2 1.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.2 2.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 1.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 2.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 2.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 1.3 GO:0090166 Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.2 0.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 3.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.4 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 2.2 GO:0048733 sebaceous gland development(GO:0048733)
0.1 3.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 3.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 1.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 2.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 2.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.9 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 2.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.8 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.7 GO:0044351 macropinocytosis(GO:0044351)
0.1 1.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.7 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 1.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 1.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.1 1.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.3 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 1.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:0021553 olfactory nerve development(GO:0021553)
0.1 1.7 GO:0007172 signal complex assembly(GO:0007172)
0.1 1.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.2 GO:0040040 thermosensory behavior(GO:0040040)
0.1 2.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 1.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.8 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 1.6 GO:0033622 integrin activation(GO:0033622)
0.0 0.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.6 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 2.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 6.7 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 3.7 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 3.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 2.0 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.6 GO:0000050 urea cycle(GO:0000050)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 1.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.7 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 1.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 1.9 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.7 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0042113 B cell activation(GO:0042113)
0.0 3.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 1.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.5 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.5 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 1.3 GO:1901998 toxin transport(GO:1901998)
0.0 0.7 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 1.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 2.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.7 GO:1903859 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.9 GO:0097178 ruffle assembly(GO:0097178)
0.0 1.0 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0048585 negative regulation of response to stimulus(GO:0048585)
0.0 1.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0043065 positive regulation of apoptotic process(GO:0043065)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.7 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.5 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0043614 multi-eIF complex(GO:0043614)
0.7 2.1 GO:1990032 parallel fiber(GO:1990032)
0.4 3.5 GO:1990393 3M complex(GO:1990393)
0.4 3.0 GO:0097452 GAIT complex(GO:0097452)
0.4 1.1 GO:0075341 host cell PML body(GO:0075341)
0.3 1.0 GO:0005745 m-AAA complex(GO:0005745)
0.3 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.3 0.8 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.3 6.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 2.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 2.2 GO:0033263 CORVET complex(GO:0033263)
0.2 6.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 4.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 2.9 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 4.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 3.5 GO:0097227 sperm annulus(GO:0097227)
0.2 3.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 2.0 GO:0030314 junctional membrane complex(GO:0030314)
0.2 1.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 4.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.4 GO:0033011 perinuclear theca(GO:0033011)
0.1 3.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.0 GO:0045298 tubulin complex(GO:0045298)
0.1 1.6 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 6.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.9 GO:0016589 NURF complex(GO:0016589)
0.1 1.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 1.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 1.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.7 GO:0016600 flotillin complex(GO:0016600)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 4.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 4.2 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 9.5 GO:0005938 cell cortex(GO:0005938)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 2.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 10.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.7 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
1.3 8.9 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.0 3.0 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.8 3.9 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.7 2.7 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.5 1.6 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.4 1.7 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.4 3.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.3 2.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.3 2.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 2.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.3 6.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 0.8 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.3 1.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 2.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 2.9 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 2.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.9 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 4.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 2.3 GO:0036122 BMP binding(GO:0036122)
0.2 1.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.9 GO:0031386 protein tag(GO:0031386)
0.1 1.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 5.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 2.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 3.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.5 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.4 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 3.0 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 1.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 3.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 3.6 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 2.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 5.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.7 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.5 GO:0015266 protein channel activity(GO:0015266)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.9 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.3 GO:0043621 protein self-association(GO:0043621)
0.0 1.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 8.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 4.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 7.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 5.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 3.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 6.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 4.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 4.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.6 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 3.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 2.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines