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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BACH2

Z-value: 0.64

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
ENSG00000112182.10 BTB domain and CNC homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH2hg19_v2_chr6_-_91006461_910065170.751.6e-04Click!

Activity profile of BACH2 motif

Sorted Z-values of BACH2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39769005 6.53 ENST00000301653.4
ENST00000593067.1
keratin 16
chr2_+_113875466 4.70 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
interleukin 1 receptor antagonist
chr1_+_153003671 3.80 ENST00000307098.4
small proline-rich protein 1B
chr1_+_152881014 3.52 ENST00000368764.3
ENST00000392667.2
involucrin
chr2_+_208104351 3.25 ENST00000440326.1
AC007879.7
chr3_-_151034734 3.21 ENST00000260843.4
G protein-coupled receptor 87
chr18_+_21452964 3.15 ENST00000587184.1
laminin, alpha 3
chr18_+_21452804 3.14 ENST00000269217.6
laminin, alpha 3
chr2_+_208104497 3.00 ENST00000430494.1
AC007879.7
chr11_-_119993979 2.64 ENST00000524816.3
ENST00000525327.1
tripartite motif containing 29
chr1_-_156675368 2.64 ENST00000368222.3
cellular retinoic acid binding protein 2
chr18_+_61143994 2.41 ENST00000382771.4
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr20_-_1309809 2.19 ENST00000360779.3
syndecan binding protein (syntenin) 2
chr6_+_41604747 2.14 ENST00000419164.1
ENST00000373051.2
MyoD family inhibitor
chr10_+_75668916 1.97 ENST00000481390.1
plasminogen activator, urokinase
chr9_-_114246332 1.96 ENST00000602978.1
KIAA0368
chr20_+_44637526 1.96 ENST00000372330.3
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr5_+_149877334 1.96 ENST00000523767.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr6_+_106959718 1.92 ENST00000369066.3
absent in melanoma 1
chr6_-_113953705 1.89 ENST00000452675.1
RP11-367G18.1
chr16_-_2908155 1.88 ENST00000571228.1
ENST00000161006.3
protease, serine, 22
chr3_+_184016986 1.88 ENST00000417952.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr1_+_150480551 1.85 ENST00000369049.4
ENST00000369047.4
extracellular matrix protein 1
chr11_-_102668879 1.80 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr1_+_150480576 1.80 ENST00000346569.6
extracellular matrix protein 1
chr18_+_61144160 1.74 ENST00000489441.1
ENST00000424602.1
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr19_-_51587502 1.70 ENST00000156499.2
ENST00000391802.1
kallikrein-related peptidase 14
chr2_+_169926047 1.67 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr6_+_41604620 1.66 ENST00000432027.1
MyoD family inhibitor
chr8_+_144821557 1.64 ENST00000534398.1
FAM83H antisense RNA 1 (head to head)
chr19_-_39264072 1.60 ENST00000599035.1
ENST00000378626.4
lectin, galactoside-binding, soluble, 7
chr1_+_26606608 1.58 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr19_+_39279838 1.57 ENST00000314980.4
lectin, galactoside-binding, soluble, 7B
chr11_+_12308447 1.52 ENST00000256186.2
MICAL C-terminal like
chr12_-_95009837 1.51 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr1_+_223889310 1.47 ENST00000434648.1
calpain 2, (m/II) large subunit
chr8_+_22844995 1.47 ENST00000524077.1
Rho-related BTB domain containing 2
chr8_+_120220561 1.46 ENST00000276681.6
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr6_-_35888824 1.39 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr17_+_37030127 1.33 ENST00000419929.1
LIM and SH3 protein 1
chr1_+_36621174 1.25 ENST00000429533.2
MAP7 domain containing 1
chr12_-_95010147 1.24 ENST00000548918.1
transmembrane and coiled-coil domain family 3
chr8_+_123875624 1.23 ENST00000534247.1
zinc fingers and homeoboxes 2
chr11_-_102826434 1.23 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr16_+_57662138 1.22 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr5_+_150020240 1.22 ENST00000519664.1
synaptopodin
chr19_-_51523412 1.20 ENST00000391805.1
ENST00000599077.1
kallikrein-related peptidase 10
chr2_+_220144168 1.15 ENST00000392087.2
ENST00000442681.1
ENST00000439026.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr18_+_61442629 1.14 ENST00000398019.2
ENST00000540675.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_-_62323702 1.12 ENST00000530285.1
AHNAK nucleoprotein
chr6_+_74405501 1.09 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr1_+_223889285 1.08 ENST00000433674.2
calpain 2, (m/II) large subunit
chr8_+_22844913 1.08 ENST00000519685.1
Rho-related BTB domain containing 2
chr6_+_74405804 1.07 ENST00000287097.5
CD109 molecule
chr6_-_35888905 1.06 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr19_-_51523275 1.05 ENST00000309958.3
kallikrein-related peptidase 10
chr19_+_19516561 1.01 ENST00000457895.2
GATA zinc finger domain containing 2A
chr2_+_47596287 1.00 ENST00000263735.4
epithelial cell adhesion molecule
chr19_-_35992780 0.99 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
dermokine
chr4_-_74088800 0.98 ENST00000509867.2
ankyrin repeat domain 17
chr6_-_56819385 0.98 ENST00000370754.5
ENST00000449297.2
dystonin
chr7_+_73245193 0.94 ENST00000340958.2
claudin 4
chr1_-_6551720 0.93 ENST00000377728.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr11_+_10477733 0.92 ENST00000528723.1
adenosine monophosphate deaminase 3
chr14_+_71165292 0.92 ENST00000553682.1
RP6-65G23.1
chr14_-_75083313 0.92 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr2_+_47596634 0.91 ENST00000419334.1
epithelial cell adhesion molecule
chr6_-_159239257 0.91 ENST00000337147.7
ENST00000392177.4
ezrin
chr1_-_52344416 0.91 ENST00000544028.1
nardilysin (N-arginine dibasic convertase)
chr1_+_154377669 0.90 ENST00000368485.3
ENST00000344086.4
interleukin 6 receptor
chr16_+_67571351 0.86 ENST00000428437.2
ENST00000569253.1
family with sequence similarity 65, member A
chr5_+_138089100 0.85 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr12_-_48152853 0.84 ENST00000171000.4
Rap guanine nucleotide exchange factor (GEF) 3
chr7_-_107643567 0.84 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
laminin, beta 1
chr10_+_86088381 0.83 ENST00000224756.8
ENST00000372088.2
coiled-coil serine-rich protein 2
chr1_-_27816641 0.83 ENST00000430629.2
WAS protein family, member 2
chr17_+_48611853 0.83 ENST00000507709.1
ENST00000515126.1
ENST00000507467.1
epsin 3
chr1_+_26605618 0.82 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr3_-_69402828 0.81 ENST00000460709.1
FERM domain containing 4B
chr16_+_57662527 0.81 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
G protein-coupled receptor 56
chr17_+_30771279 0.79 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr2_+_220144052 0.79 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr1_+_156863470 0.78 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
platelet endothelial aggregation receptor 1
chr2_+_231921574 0.76 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr5_-_175843569 0.75 ENST00000310418.4
ENST00000345807.2
clathrin, light chain B
chrX_+_41193407 0.75 ENST00000457138.2
ENST00000441189.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr11_-_8739566 0.75 ENST00000533020.1
suppression of tumorigenicity 5
chr4_+_159727222 0.74 ENST00000512986.1
folliculin interacting protein 2
chr1_-_108231101 0.73 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr10_+_86088337 0.71 ENST00000359979.4
coiled-coil serine-rich protein 2
chr11_-_6341844 0.70 ENST00000303927.3
protein kinase C, delta binding protein
chr7_+_134528635 0.69 ENST00000445569.2
caldesmon 1
chr6_+_292051 0.69 ENST00000344450.5
dual specificity phosphatase 22
chr11_+_10476851 0.69 ENST00000396553.2
adenosine monophosphate deaminase 3
chr5_+_149877440 0.68 ENST00000518299.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr4_+_159727272 0.68 ENST00000379346.3
folliculin interacting protein 2
chr5_-_41794663 0.67 ENST00000510634.1
3-oxoacid CoA transferase 1
chr2_-_220117867 0.66 ENST00000456818.1
ENST00000447205.1
tubulin, alpha 4a
chr10_+_127661942 0.65 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr11_-_128894053 0.65 ENST00000392657.3
Rho GTPase activating protein 32
chr11_-_8739383 0.63 ENST00000531060.1
suppression of tumorigenicity 5
chr16_+_53133070 0.63 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr19_-_36019123 0.62 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr11_-_46848393 0.61 ENST00000526496.1
cytoskeleton associated protein 5
chr11_-_66104237 0.61 ENST00000530056.1
Ras and Rab interactor 1
chr12_-_48152611 0.61 ENST00000389212.3
Rap guanine nucleotide exchange factor (GEF) 3
chr16_+_89988259 0.61 ENST00000554444.1
ENST00000556565.1
Tubulin beta-3 chain
chr1_-_6662919 0.60 ENST00000377658.4
ENST00000377663.3
kelch-like family member 21
chr9_-_112179990 0.60 ENST00000394827.3
protein tyrosine phosphatase, non-receptor type 3
chr11_-_66103867 0.60 ENST00000424433.2
Ras and Rab interactor 1
chr4_+_170581213 0.60 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr12_-_118490403 0.60 ENST00000535496.1
WD repeat and SOCS box containing 2
chr16_+_57662596 0.59 ENST00000567397.1
ENST00000568979.1
G protein-coupled receptor 56
chr1_+_223900034 0.59 ENST00000295006.5
calpain 2, (m/II) large subunit
chr11_+_59522837 0.59 ENST00000437946.2
syntaxin 3
chr1_-_179112189 0.58 ENST00000512653.1
ENST00000344730.3
c-abl oncogene 2, non-receptor tyrosine kinase
chr17_+_79651007 0.58 ENST00000572392.1
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr9_-_130637244 0.57 ENST00000373156.1
adenylate kinase 1
chr11_-_66103932 0.57 ENST00000311320.4
Ras and Rab interactor 1
chr19_+_6740888 0.57 ENST00000596673.1
thyroid hormone receptor interactor 10
chrX_-_129244336 0.56 ENST00000434609.1
E74-like factor 4 (ets domain transcription factor)
chr2_+_220143989 0.56 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr8_-_29939933 0.56 ENST00000522794.1
transmembrane protein 66
chr6_+_150070857 0.55 ENST00000544496.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_-_151965048 0.55 ENST00000368809.1
S100 calcium binding protein A10
chr1_-_157108130 0.55 ENST00000368192.4
ets variant 3
chr16_+_57662419 0.52 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
G protein-coupled receptor 56
chr10_+_121410882 0.52 ENST00000369085.3
BCL2-associated athanogene 3
chr17_+_65375082 0.52 ENST00000584471.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_+_79071365 0.52 ENST00000576756.1
BAI1-associated protein 2
chr19_+_49467232 0.52 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
chr5_-_41794313 0.51 ENST00000512084.1
3-oxoacid CoA transferase 1
chr3_+_11178779 0.50 ENST00000438284.2
histamine receptor H1
chr7_+_143078379 0.49 ENST00000449630.1
ENST00000457235.1
zyxin
chr5_+_150020214 0.49 ENST00000307662.4
synaptopodin
chr3_+_187930429 0.48 ENST00000420410.1
LIM domain containing preferred translocation partner in lipoma
chr3_-_187454281 0.48 ENST00000232014.4
B-cell CLL/lymphoma 6
chr2_+_233562015 0.47 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GRB10 interacting GYF protein 2
chr2_-_85641162 0.47 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr15_+_22892663 0.44 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
cytoplasmic FMR1 interacting protein 1
chr1_+_36554470 0.44 ENST00000373178.4
ADP-ribosylhydrolase like 2
chr4_+_108746282 0.44 ENST00000503862.1
sphingomyelin synthase 2
chr4_+_108745711 0.44 ENST00000394684.4
sphingomyelin synthase 2
chr3_+_19988885 0.44 ENST00000422242.1
RAB5A, member RAS oncogene family
chr17_+_35851570 0.44 ENST00000394386.1
dual specificity phosphatase 14
chr4_-_100356291 0.44 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr15_+_57211318 0.43 ENST00000557947.1
transcription factor 12
chr18_-_74207146 0.43 ENST00000443185.2
zinc finger protein 516
chr4_-_146019693 0.42 ENST00000514390.1
anaphase promoting complex subunit 10
chrX_-_16730984 0.42 ENST00000380241.3
CTP synthase 2
chr9_-_35112376 0.42 ENST00000488109.2
family with sequence similarity 214, member B
chr5_+_14664762 0.41 ENST00000284274.4
family with sequence similarity 105, member B
chr1_+_36621697 0.39 ENST00000373150.4
ENST00000373151.2
MAP7 domain containing 1
chr19_+_7953417 0.39 ENST00000600345.1
ENST00000598224.1
leucine rich repeat containing 8 family, member E
chr17_+_28256874 0.38 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr17_+_75315654 0.38 ENST00000590595.1
septin 9
chr19_+_36630855 0.37 ENST00000589146.1
calpain, small subunit 1
chr2_-_96926313 0.36 ENST00000435268.1
transmembrane protein 127
chr17_+_75315534 0.35 ENST00000590294.1
ENST00000329047.8
septin 9
chr1_-_204121102 0.35 ENST00000367202.4
ethanolamine kinase 2
chr9_+_34992846 0.34 ENST00000443266.1
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_-_98241713 0.33 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
claudin domain containing 1
chr1_-_204121013 0.33 ENST00000367201.3
ethanolamine kinase 2
chr7_+_116312411 0.33 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr7_-_35734730 0.33 ENST00000396081.1
ENST00000311350.3
HERPUD family member 2
chr15_+_44829334 0.32 ENST00000535391.1
eukaryotic translation initiation factor 3, subunit J
chr12_-_105352047 0.31 ENST00000432951.1
ENST00000415674.1
ENST00000424946.1
solute carrier family 41 (magnesium transporter), member 2
chr7_-_35734607 0.31 ENST00000427455.1
HERPUD family member 2
chr6_+_150070831 0.30 ENST00000367380.5
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr12_-_105352080 0.30 ENST00000433540.1
solute carrier family 41 (magnesium transporter), member 2
chr17_-_39538550 0.30 ENST00000394001.1
keratin 34
chr6_+_44214824 0.30 ENST00000371646.5
ENST00000353801.3
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr16_+_22308717 0.30 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr9_-_114246635 0.30 ENST00000338205.5
KIAA0368
chrX_-_16730688 0.30 ENST00000359276.4
CTP synthase 2
chr19_-_51538148 0.29 ENST00000319590.4
ENST00000250351.4
kallikrein-related peptidase 12
chrX_+_3189861 0.29 ENST00000457435.1
ENST00000420429.2
chromosome X open reading frame 28
chr12_-_118490217 0.28 ENST00000542304.1
WD repeat and SOCS box containing 2
chr7_-_150721570 0.28 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
autophagy related 9B
chr2_+_201980827 0.28 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CASP8 and FADD-like apoptosis regulator
chr22_+_22764088 0.27 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr3_+_187930491 0.27 ENST00000443217.1
LIM domain containing preferred translocation partner in lipoma
chr3_+_69134080 0.27 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr1_-_157108266 0.27 ENST00000326786.4
ets variant 3
chr19_+_50706866 0.27 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr19_-_51538118 0.27 ENST00000529888.1
kallikrein-related peptidase 12
chr22_+_20861858 0.26 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
mediator complex subunit 15
chr17_-_18161870 0.25 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
flightless I homolog (Drosophila)
chr9_+_4985016 0.25 ENST00000539801.1
Janus kinase 2
chr1_-_204121298 0.25 ENST00000367199.2
ethanolamine kinase 2
chr10_-_73611046 0.24 ENST00000394934.1
ENST00000394936.3
prosaposin
chr14_-_51863853 0.24 ENST00000556762.1
RP11-255G12.3
chr11_-_65667997 0.24 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr6_-_119031228 0.23 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr10_+_85899196 0.22 ENST00000372134.3
growth hormone inducible transmembrane protein
chr22_+_20862321 0.22 ENST00000541476.1
ENST00000438962.1
mediator complex subunit 15
chr19_+_7953384 0.22 ENST00000306708.6
leucine rich repeat containing 8 family, member E
chr17_-_27467418 0.22 ENST00000528564.1
myosin XVIIIA
chr2_-_65593784 0.21 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr18_+_32290218 0.21 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5 4.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5 2.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.5 2.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 8.5 GO:0051546 keratinocyte migration(GO:0051546)
0.4 1.1 GO:0002384 hepatic immune response(GO:0002384)
0.3 2.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 1.5 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.3 1.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.3 1.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 1.6 GO:0006196 AMP catabolic process(GO:0006196)
0.2 1.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 1.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 4.3 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.2 2.6 GO:0006477 protein sulfation(GO:0006477)
0.2 0.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 6.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 1.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 3.8 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 0.9 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 3.1 GO:0016540 protein autoprocessing(GO:0016540)
0.1 2.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 1.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.7 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 3.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.5 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 3.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.6 GO:0007320 insemination(GO:0007320)
0.1 1.5 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.8 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.4 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.3 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.6 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 3.8 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 0.9 GO:0030091 protein repair(GO:0030091)
0.1 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.5 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 1.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 3.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.8 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.4 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 1.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.6 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 1.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 2.6 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.0 0.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.0 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 2.5 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.5 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) positive regulation of response to alcohol(GO:1901421)
0.0 1.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.5 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.7 GO:0006936 muscle contraction(GO:0006936)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0034515 proteasome storage granule(GO:0034515)
0.6 6.3 GO:0005610 laminin-5 complex(GO:0005610)
0.6 1.7 GO:0097444 spine apparatus(GO:0097444)
0.2 0.9 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 1.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 3.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 1.0 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.4 GO:0043257 laminin-8 complex(GO:0043257)
0.1 7.5 GO:0001533 cornified envelope(GO:0001533)
0.1 3.0 GO:0031143 pseudopodium(GO:0031143)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 1.6 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0016600 flotillin complex(GO:0016600)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.8 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 1.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 2.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.5 3.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.4 2.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.4 1.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.3 1.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 0.8 GO:1990175 EH domain binding(GO:1990175)
0.2 1.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.7 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.2 1.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.7 GO:0003883 CTP synthase activity(GO:0003883)
0.1 2.6 GO:0019841 retinol binding(GO:0019841)
0.1 0.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 3.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 5.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 2.0 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.9 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.8 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 2.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 2.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 12.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 3.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.8 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 9.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 5.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 8.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.4 ST STAT3 PATHWAY STAT3 Pathway
0.1 5.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 4.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 3.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 7.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 2.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction