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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BATF3

Z-value: 0.30

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Transcription factors associated with BATF3

Gene Symbol Gene ID Gene Info
BATF3
ENSG00000123685.4 basic leucine zipper ATF-like transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BATF3hg19_v2_chr1_-_212873267_2128733320.445.3e-02Click!

Activity profile of BATF3 motif

Sorted Z-values of BATF3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_28129656 0.62 ENST00000263181.6
KIF18A
kinesin family member 18A
chr14_-_35182994 0.55 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr11_+_12696102 0.53 ENST00000527636.1
ENST00000527376.1
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr4_-_104119528 0.52 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr19_+_47616682 0.50 ENST00000594526.1
SAE1
SUMO1 activating enzyme subunit 1
chr3_-_134092561 0.47 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr10_+_35484793 0.38 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr4_-_104119488 0.37 ENST00000514974.1
CENPE
centromere protein E, 312kDa
chrX_-_135056106 0.35 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chr17_-_49124230 0.34 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr15_+_34394257 0.33 ENST00000397766.2
PGBD4
piggyBac transposable element derived 4
chr11_+_12695944 0.31 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_-_119182506 0.27 ENST00000468676.1
TMEM39A
transmembrane protein 39A
chr7_-_93633658 0.26 ENST00000433727.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr22_+_31518938 0.25 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr2_-_65659762 0.24 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr15_+_91498089 0.23 ENST00000394258.2
ENST00000555155.1
RCCD1
RCC1 domain containing 1
chr14_-_77495007 0.23 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr1_-_70671216 0.23 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr7_-_93633684 0.23 ENST00000222547.3
ENST00000425626.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr20_+_42219559 0.22 ENST00000373030.3
ENST00000373039.4
IFT52
intraflagellar transport 52 homolog (Chlamydomonas)
chr5_+_112849373 0.22 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr17_+_29421987 0.22 ENST00000431387.4
NF1
neurofibromin 1
chr17_+_7835419 0.20 ENST00000576538.1
ENST00000380262.3
ENST00000563694.1
ENST00000380255.3
ENST00000570782.1
CNTROB
centrobin, centrosomal BRCA2 interacting protein
chr15_+_42841008 0.20 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2
HAUS augmin-like complex, subunit 2
chr4_-_39367949 0.19 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chrX_-_135056216 0.17 ENST00000305963.2
MMGT1
membrane magnesium transporter 1
chr14_+_20811722 0.16 ENST00000429687.3
PARP2
poly (ADP-ribose) polymerase 2
chr4_+_170581213 0.15 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr2_-_43823119 0.15 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA
thyroid adenoma associated
chr8_-_67090825 0.14 ENST00000276571.3
CRH
corticotropin releasing hormone
chr3_-_52312337 0.14 ENST00000469000.1
WDR82
WD repeat domain 82
chr15_-_66790146 0.13 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr11_+_102217936 0.13 ENST00000532832.1
ENST00000530675.1
ENST00000533742.1
ENST00000227758.2
ENST00000532672.1
ENST00000531259.1
ENST00000527465.1
BIRC2
baculoviral IAP repeat containing 2
chr17_+_29421900 0.13 ENST00000358273.4
ENST00000356175.3
NF1
neurofibromin 1
chr16_+_58535372 0.13 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr2_-_220264703 0.12 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr8_+_37594185 0.12 ENST00000518586.1
ENST00000335171.6
ENST00000521644.1
ERLIN2
ER lipid raft associated 2
chr19_+_18723660 0.11 ENST00000262817.3
TMEM59L
transmembrane protein 59-like
chr18_+_76829385 0.10 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr6_-_106773291 0.10 ENST00000343245.3
ATG5
autophagy related 5
chr6_-_106773610 0.09 ENST00000369076.3
ENST00000369070.1
ATG5
autophagy related 5
chr19_-_47616992 0.09 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr14_+_20811766 0.08 ENST00000250416.5
ENST00000527915.1
PARP2
poly (ADP-ribose) polymerase 2
chr16_+_3068393 0.08 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr1_+_110527308 0.08 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr14_-_50053081 0.08 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr11_-_65793948 0.08 ENST00000312106.5
CATSPER1
cation channel, sperm associated 1
chr11_+_66059339 0.07 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr11_+_28129795 0.07 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr19_-_18392422 0.06 ENST00000252818.3
JUND
jun D proto-oncogene
chr2_-_43823093 0.06 ENST00000405006.4
THADA
thyroid adenoma associated
chr3_-_52312636 0.06 ENST00000296490.3
WDR82
WD repeat domain 82
chr10_-_128975273 0.05 ENST00000424811.2
FAM196A
family with sequence similarity 196, member A
chr7_-_121944491 0.04 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr9_-_99381660 0.04 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr19_-_5340730 0.04 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr2_-_202645835 0.04 ENST00000264276.6
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr2_-_65357225 0.04 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A
RAB1A, member RAS oncogene family
chr12_+_10365082 0.04 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr2_-_202645612 0.04 ENST00000409632.2
ENST00000410052.1
ENST00000467448.1
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr6_+_37400974 0.03 ENST00000455891.1
ENST00000373451.4
CMTR1
cap methyltransferase 1
chr15_+_96904487 0.03 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr8_+_37594130 0.03 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2
ER lipid raft associated 2
chr19_+_8455200 0.02 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr11_-_85376121 0.02 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr16_+_68057153 0.01 ENST00000358896.6
ENST00000568099.2
DUS2
dihydrouridine synthase 2
chr15_-_34394119 0.01 ENST00000256545.4
EMC7
ER membrane protein complex subunit 7
chr10_+_123922941 0.01 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr16_+_68057179 0.00 ENST00000567100.1
ENST00000432752.1
ENST00000569289.1
ENST00000564781.1
DUS2
dihydrouridine synthase 2
chr8_+_37594103 0.00 ENST00000397228.2
ERLIN2
ER lipid raft associated 2

Network of associatons between targets according to the STRING database.

First level regulatory network of BATF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.2 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314) positive regulation of corticosterone secretion(GO:2000854)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:1902525 positive regulation of protein K63-linked ubiquitination(GO:1902523) regulation of protein monoubiquitination(GO:1902525) positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 1.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.9 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo