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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for CCCUGAG
Z-value: 1.53
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miRNA associated with seed CCCUGAG
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_54779511 Show fit | 2.70 |
ENST00000551109.1
ENST00000546970.1 |
zinc finger protein 385A |
|
| chr19_-_1863567 Show fit | 2.41 |
ENST00000250916.4
|
Kruppel-like factor 16 |
|
| chr6_+_138188551 Show fit | 2.39 |
ENST00000237289.4
ENST00000433680.1 |
tumor necrosis factor, alpha-induced protein 3 |
|
| chr2_+_75061108 Show fit | 2.17 |
ENST00000290573.2
|
hexokinase 2 |
|
| chr13_-_86373536 Show fit | 2.03 |
ENST00000400286.2
|
SLIT and NTRK-like family, member 6 |
|
| chr1_+_151483855 Show fit | 1.92 |
ENST00000427934.2
ENST00000271636.7 |
cingulin |
|
| chr4_-_2264015 Show fit | 1.85 |
ENST00000337190.2
|
MAX dimerization protein 4 |
|
| chr11_-_64612041 Show fit | 1.75 |
ENST00000342711.5
|
CDC42 binding protein kinase gamma (DMPK-like) |
|
| chr5_-_175964366 Show fit | 1.71 |
ENST00000274811.4
|
ring finger protein 44 |
|
| chr20_+_2673383 Show fit | 1.69 |
ENST00000380648.4
ENST00000342725.5 |
early B-cell factor 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CCCUGAG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.7 | GO:1902162 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.8 | 2.4 | GO:0034147 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349) |
| 0.0 | 2.4 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.3 | 2.2 | GO:1904925 | negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 0.0 | 2.2 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.3 | 2.0 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.2 | 1.7 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.1 | 1.7 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.0 | 1.7 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.0 | 1.7 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 2.0 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 1.6 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 1.6 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 1.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.3 | 1.3 | GO:0060187 | cell pole(GO:0060187) |
| 0.0 | 1.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 1.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 1.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 1.2 | GO:0035580 | specific granule lumen(GO:0035580) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.4 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 4.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 3.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 3.4 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 2.7 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 2.4 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 2.4 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 2.3 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 2.3 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.2 | 2.2 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 3.7 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 3.1 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 2.9 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.5 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 2.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 2.0 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 2.0 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.0 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.0 | 1.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 2.3 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 1.7 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.1 | 1.6 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 1.5 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 0.0 | 1.3 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 1.3 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 1.2 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 1.2 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 1.1 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |