Project
SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for CEBPE_CEBPD
Z-value: 1.26
Motif logo
Transcription factors associated with CEBPE_CEBPD
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CEBPD | hg19_v2_chr8_-_48651648_48651648 | -0.31 | 1.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_18287801 Show fit | 6.17 |
ENST00000532858.1
ENST00000405158.2 |
serum amyloid A1 |
|
| chr8_+_124194875 Show fit | 6.16 |
ENST00000522648.1
ENST00000276699.6 |
family with sequence similarity 83, member A |
|
| chr8_+_124194752 Show fit | 5.88 |
ENST00000318462.6
|
family with sequence similarity 83, member A |
|
| chr11_+_18287721 Show fit | 5.79 |
ENST00000356524.4
|
serum amyloid A1 |
|
| chr2_-_113594279 Show fit | 5.71 |
ENST00000416750.1
ENST00000418817.1 ENST00000263341.2 |
interleukin 1, beta |
|
| chr11_-_18270182 Show fit | 5.35 |
ENST00000528349.1
ENST00000526900.1 ENST00000529528.1 ENST00000414546.2 ENST00000256733.4 |
serum amyloid A2 |
|
| chr8_-_6735451 Show fit | 5.10 |
ENST00000297439.3
|
defensin, beta 1 |
|
| chr2_+_113885138 Show fit | 3.74 |
ENST00000409930.3
|
interleukin 1 receptor antagonist |
|
| chr12_-_123187890 Show fit | 3.43 |
ENST00000328880.5
|
hydroxycarboxylic acid receptor 2 |
|
| chr5_+_49963239 Show fit | 3.31 |
ENST00000505554.1
|
poly (ADP-ribose) polymerase family, member 8 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CEBPE_CEBPD
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 12.5 | GO:0050716 | positive regulation of interleukin-1 secretion(GO:0050716) |
| 0.0 | 11.2 | GO:0007173 | epidermal growth factor receptor signaling pathway(GO:0007173) |
| 0.9 | 9.1 | GO:0070163 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) |
| 0.7 | 6.6 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.5 | 5.4 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.1 | 5.2 | GO:0006953 | acute-phase response(GO:0006953) |
| 1.3 | 5.1 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.2 | 5.1 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.3 | 4.1 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.4 | 3.1 | GO:1903575 | cornified envelope assembly(GO:1903575) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 12.0 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.1 | 5.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 1.3 | 5.1 | GO:1990742 | microvesicle(GO:1990742) |
| 0.6 | 4.4 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.0 | 2.6 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 2.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.2 | 2.3 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 2.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 2.2 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.0 | 2.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 18.7 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.5 | 12.0 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.3 | 5.8 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 5.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 5.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 1.7 | 5.1 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 0.1 | 4.5 | GO:0001848 | complement binding(GO:0001848) |
| 1.2 | 3.7 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 0.0 | 3.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 3.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 12.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.2 | 7.9 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 6.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 6.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 6.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.2 | 5.3 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 5.2 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 3.5 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 2.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 2.0 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 12.0 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.3 | 7.6 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.0 | 6.6 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 5.9 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.3 | 5.1 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 3.3 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.1 | 3.1 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 2.2 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 1.6 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.0 | 1.3 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |