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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CENPB

Z-value: 1.16

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Transcription factors associated with CENPB

Gene Symbol Gene ID Gene Info
CENPB
ENSG00000125817.7 centromere protein B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CENPBhg19_v2_chr20_-_3767324_37674430.769.8e-05Click!

Activity profile of CENPB motif

Sorted Z-values of CENPB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrY_+_2709527 5.09 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chrY_+_2709906 5.04 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr17_-_26926005 3.11 ENST00000536674.2
SPAG5
sperm associated antigen 5
chr2_+_11295498 2.88 ENST00000295083.3
ENST00000441908.2
PQLC3
PQ loop repeat containing 3
chr11_+_82612740 2.86 ENST00000524921.1
ENST00000528759.1
ENST00000525361.1
ENST00000430323.2
ENST00000533655.1
ENST00000532764.1
ENST00000532589.1
ENST00000525388.1
C11orf82
chromosome 11 open reading frame 82
chr2_+_11295624 2.86 ENST00000402361.1
ENST00000428481.1
PQLC3
PQ loop repeat containing 3
chr1_+_64239657 2.52 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr20_-_52790512 2.49 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr20_+_3776371 2.38 ENST00000245960.5
CDC25B
cell division cycle 25B
chr2_+_73114489 2.34 ENST00000234454.5
SPR
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
chr12_+_25348139 2.32 ENST00000557540.2
ENST00000381356.4
LYRM5
LYR motif containing 5
chr1_-_167905225 2.27 ENST00000367846.4
MPC2
mitochondrial pyruvate carrier 2
chr17_-_72869086 2.12 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
FDXR
ferredoxin reductase
chr10_+_90639491 2.09 ENST00000371926.3
ENST00000371927.3
STAMBPL1
STAM binding protein-like 1
chr19_+_35168567 2.08 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr12_+_25348186 2.04 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr10_+_30723105 2.02 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr15_-_82338460 1.88 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr22_+_23412479 1.86 ENST00000248996.4
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr10_+_30723045 1.85 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr7_-_99698338 1.81 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr11_+_65222698 1.78 ENST00000309775.7
AP000769.1
Uncharacterized protein
chr5_-_59064458 1.77 ENST00000502575.1
ENST00000507116.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_+_30722866 1.76 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr15_-_65067773 1.73 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr10_+_30723533 1.70 ENST00000413724.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr22_+_19467261 1.62 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45
cell division cycle 45
chr17_-_72869140 1.61 ENST00000583917.1
ENST00000293195.5
ENST00000442102.2
FDXR
ferredoxin reductase
chr10_+_22610124 1.57 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr14_-_45722605 1.49 ENST00000310806.4
MIS18BP1
MIS18 binding protein 1
chrX_+_100353153 1.48 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
CENPI
centromere protein I
chr15_-_48470544 1.46 ENST00000267836.6
MYEF2
myelin expression factor 2
chr6_-_136571400 1.45 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
MTFR2
mitochondrial fission regulator 2
chr11_-_66115032 1.35 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr19_-_41220540 1.28 ENST00000594490.1
ADCK4
aarF domain containing kinase 4
chr11_-_560703 1.26 ENST00000441853.1
ENST00000329451.3
C11orf35
chromosome 11 open reading frame 35
chr1_-_156390128 1.21 ENST00000368242.3
C1orf61
chromosome 1 open reading frame 61
chr7_+_76054224 1.19 ENST00000394857.3
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr6_-_39197226 1.19 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr15_+_63569785 1.18 ENST00000380343.4
ENST00000560353.1
APH1B
APH1B gamma secretase subunit
chr15_-_48470558 1.18 ENST00000324324.7
MYEF2
myelin expression factor 2
chr3_+_149531607 1.16 ENST00000468648.1
ENST00000459632.1
RNF13
ring finger protein 13
chr12_-_110906027 1.16 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN3
GPN-loop GTPase 3
chr4_-_170679024 1.15 ENST00000393381.2
C4orf27
chromosome 4 open reading frame 27
chr14_-_102026643 1.15 ENST00000555882.1
ENST00000554441.1
ENST00000553729.1
ENST00000557109.1
ENST00000557532.1
ENST00000554694.1
ENST00000554735.1
ENST00000555174.1
ENST00000557661.1
DIO3OS
DIO3 opposite strand/antisense RNA (head to head)
chr6_-_105627735 1.14 ENST00000254765.3
POPDC3
popeye domain containing 3
chr14_+_50779029 1.11 ENST00000245448.6
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr2_-_241500168 1.11 ENST00000443318.1
ENST00000411765.1
ANKMY1
ankyrin repeat and MYND domain containing 1
chr2_-_241500447 1.10 ENST00000536462.1
ENST00000405002.1
ENST00000441168.1
ENST00000403283.1
ANKMY1
ankyrin repeat and MYND domain containing 1
chr20_+_306221 1.08 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr12_+_109592477 1.07 ENST00000544726.1
ACACB
acetyl-CoA carboxylase beta
chr19_+_34919257 1.06 ENST00000246548.4
ENST00000590048.2
UBA2
ubiquitin-like modifier activating enzyme 2
chr12_+_110906169 1.05 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr16_-_66968265 1.04 ENST00000567511.1
ENST00000422424.2
FAM96B
family with sequence similarity 96, member B
chr17_+_72427477 1.04 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_-_61582579 1.03 ENST00000539419.1
ENST00000545245.1
ENST00000545405.1
ENST00000542506.1
FADS1
fatty acid desaturase 1
chrX_-_135962876 1.02 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr20_+_306177 0.98 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr12_-_40499661 0.97 ENST00000280871.4
SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13
chr1_+_151372010 0.94 ENST00000290541.6
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr6_+_108487245 0.92 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr2_+_103353367 0.91 ENST00000454536.1
ENST00000409528.1
ENST00000409173.1
TMEM182
transmembrane protein 182
chr3_-_15469006 0.89 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
METTL6
methyltransferase like 6
chr3_-_122102065 0.86 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58
coiled-coil domain containing 58
chr11_+_560956 0.84 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr19_+_50180409 0.84 ENST00000391851.4
PRMT1
protein arginine methyltransferase 1
chr6_+_30525051 0.84 ENST00000376557.3
PRR3
proline rich 3
chr6_+_30524663 0.80 ENST00000376560.3
PRR3
proline rich 3
chr12_-_40499831 0.78 ENST00000380858.1
SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13
chr11_+_126153001 0.77 ENST00000392678.3
ENST00000392680.2
TIRAP
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
chr8_-_144911469 0.77 ENST00000527744.1
ENST00000456095.2
ENST00000531897.1
ENST00000527197.1
ENST00000526459.1
ENST00000533162.1
ENST00000349157.6
PUF60
poly-U binding splicing factor 60KDa
chr11_+_66115304 0.77 ENST00000531602.1
RP11-867G23.8
Uncharacterized protein
chr10_+_70320413 0.77 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chrX_-_135962923 0.75 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr11_-_82612678 0.75 ENST00000534631.1
ENST00000531801.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr9_+_133589333 0.74 ENST00000372348.2
ENST00000393293.4
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr12_+_110562135 0.71 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
IFT81
intraflagellar transport 81 homolog (Chlamydomonas)
chr10_+_22605374 0.71 ENST00000448361.1
COMMD3
COMM domain containing 3
chr14_+_50779071 0.71 ENST00000426751.2
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr16_+_25123148 0.71 ENST00000570981.1
LCMT1
leucine carboxyl methyltransferase 1
chr3_+_149530836 0.71 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
RNF13
ring finger protein 13
chr20_+_5107532 0.71 ENST00000450570.1
ENST00000379062.4
CDS2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr16_+_30709530 0.70 ENST00000411466.2
SRCAP
Snf2-related CREBBP activator protein
chrX_+_52926322 0.69 ENST00000430150.2
ENST00000452021.2
ENST00000412319.1
FAM156B
family with sequence similarity 156, member B
chr20_-_41818536 0.69 ENST00000373193.3
ENST00000373198.4
ENST00000373201.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr15_+_63569731 0.67 ENST00000261879.5
APH1B
APH1B gamma secretase subunit
chr2_+_27805880 0.65 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512
zinc finger protein 512
chr3_-_15469045 0.65 ENST00000450816.2
METTL6
methyltransferase like 6
chr4_-_165305086 0.64 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_-_21985489 0.64 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chrX_+_135230712 0.64 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr11_+_71791849 0.64 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr2_-_103353277 0.63 ENST00000258436.5
MFSD9
major facilitator superfamily domain containing 9
chr7_+_100303676 0.63 ENST00000303151.4
POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr11_-_18610246 0.62 ENST00000379387.4
ENST00000541984.1
UEVLD
UEV and lactate/malate dehyrogenase domains
chr7_-_128050000 0.62 ENST00000489263.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr4_-_83931862 0.62 ENST00000506560.1
ENST00000442461.2
ENST00000446851.2
ENST00000340417.3
LIN54
lin-54 homolog (C. elegans)
chr17_-_7531121 0.61 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr19_+_41882598 0.61 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
TMEM91
CTC-435M10.3
transmembrane protein 91
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr19_+_50180507 0.59 ENST00000454376.2
ENST00000524771.1
PRMT1
protein arginine methyltransferase 1
chr2_+_196522032 0.59 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr14_+_24422795 0.59 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
DHRS4
dehydrogenase/reductase (SDR family) member 4
chr2_+_27805971 0.57 ENST00000413371.2
ZNF512
zinc finger protein 512
chr11_+_60609537 0.57 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr16_-_66968055 0.56 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr11_-_82612727 0.55 ENST00000531128.1
ENST00000535099.1
ENST00000527444.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr20_+_21283941 0.54 ENST00000377191.3
ENST00000430571.2
XRN2
5'-3' exoribonuclease 2
chr13_+_24144509 0.54 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr11_-_18610275 0.53 ENST00000543987.1
UEVLD
UEV and lactate/malate dehyrogenase domains
chr14_-_50778931 0.52 ENST00000555423.1
ENST00000421284.3
L2HGDH
L-2-hydroxyglutarate dehydrogenase
chr17_-_60142609 0.50 ENST00000397786.2
MED13
mediator complex subunit 13
chr11_+_126152954 0.48 ENST00000392679.1
TIRAP
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
chr17_-_64188177 0.47 ENST00000535342.2
CEP112
centrosomal protein 112kDa
chr16_-_30569584 0.46 ENST00000252797.2
ENST00000568114.1
ZNF764
AC002310.13
zinc finger protein 764
Uncharacterized protein
chr14_-_21979428 0.46 ENST00000538267.1
ENST00000298717.4
METTL3
methyltransferase like 3
chr11_+_61197572 0.45 ENST00000542074.1
ENST00000534878.1
ENST00000537782.1
ENST00000543265.1
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr2_+_85646054 0.44 ENST00000389938.2
SH2D6
SH2 domain containing 6
chr10_-_135187193 0.43 ENST00000368547.3
ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr22_-_42765174 0.43 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
Z83851.1
Z83851.1
chr19_+_51774540 0.42 ENST00000600813.1
CTD-3187F8.11
CTD-3187F8.11
chr3_-_87040233 0.41 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr20_-_55841662 0.40 ENST00000395863.3
ENST00000450594.2
BMP7
bone morphogenetic protein 7
chr12_-_25348007 0.39 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr18_-_268019 0.38 ENST00000261600.6
THOC1
THO complex 1
chr7_+_24612935 0.38 ENST00000222644.5
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr11_+_71791803 0.38 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr15_+_49447947 0.37 ENST00000327171.3
ENST00000560654.1
GALK2
galactokinase 2
chr11_-_82612549 0.37 ENST00000528082.1
ENST00000533126.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr20_-_41818373 0.36 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr13_+_24144796 0.36 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr3_+_173116225 0.35 ENST00000457714.1
NLGN1
neuroligin 1
chr20_-_45061695 0.35 ENST00000445496.2
ELMO2
engulfment and cell motility 2
chr6_-_57087042 0.35 ENST00000317483.3
RAB23
RAB23, member RAS oncogene family
chr16_-_30569801 0.35 ENST00000395091.2
ZNF764
zinc finger protein 764
chrX_-_21676442 0.34 ENST00000379499.2
KLHL34
kelch-like family member 34
chr19_-_48867171 0.34 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr19_+_48867652 0.34 ENST00000344846.2
SYNGR4
synaptogyrin 4
chr19_+_50180317 0.33 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr13_+_24153488 0.32 ENST00000382258.4
ENST00000382263.3
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr1_+_212965170 0.31 ENST00000532324.1
ENST00000366974.4
ENST00000530441.1
ENST00000526641.1
ENST00000531963.1
ENST00000366973.4
ENST00000526997.1
ENST00000488246.2
TATDN3
TatD DNase domain containing 3
chr9_-_69380597 0.30 ENST00000414341.2
CR769776.1
LOC441426 protein; Uncharacterized protein
chr2_-_152684977 0.29 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr7_-_102158157 0.27 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RASA4B
RAS p21 protein activator 4B
chr7_-_150038704 0.27 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr3_+_52232102 0.26 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
ALAS1
aminolevulinate, delta-, synthase 1
chr17_+_38296576 0.26 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr10_-_89577910 0.23 ENST00000308448.7
ENST00000541004.1
ATAD1
ATPase family, AAA domain containing 1
chr19_+_51774520 0.23 ENST00000595566.1
ENST00000594261.1
CTD-3187F8.11
CTD-3187F8.11
chr5_+_137225125 0.22 ENST00000350250.4
ENST00000508638.1
ENST00000502810.1
ENST00000508883.1
PKD2L2
polycystic kidney disease 2-like 2
chr9_-_123342415 0.22 ENST00000349780.4
ENST00000360190.4
ENST00000360822.3
ENST00000359309.3
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr17_+_53342311 0.22 ENST00000226067.5
HLF
hepatic leukemia factor
chr3_-_142166904 0.22 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr2_+_74757050 0.21 ENST00000352222.3
ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr11_-_18610214 0.20 ENST00000300038.7
ENST00000396197.3
ENST00000320750.6
UEVLD
UEV and lactate/malate dehyrogenase domains
chr19_-_46195029 0.18 ENST00000588599.1
ENST00000585392.1
ENST00000590212.1
ENST00000587367.1
ENST00000391932.3
SNRPD2
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
chr19_+_47760777 0.17 ENST00000599398.1
ENST00000595659.1
CCDC9
coiled-coil domain containing 9
chr20_-_55841398 0.17 ENST00000395864.3
BMP7
bone morphogenetic protein 7
chr2_-_136875712 0.17 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr20_+_35918035 0.17 ENST00000373606.3
ENST00000397156.3
ENST00000397150.1
ENST00000397152.3
MANBAL
mannosidase, beta A, lysosomal-like
chr3_+_157261116 0.17 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
C3orf55
chromosome 3 open reading frame 55
chr17_-_6947225 0.16 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
SLC16A11
solute carrier family 16, member 11
chr8_-_145980808 0.15 ENST00000525191.1
ZNF251
zinc finger protein 251
chr15_-_49447835 0.13 ENST00000388901.5
ENST00000299259.6
COPS2
COP9 signalosome subunit 2
chr18_+_268148 0.12 ENST00000581677.1
RP11-705O1.8
RP11-705O1.8
chr15_+_68115895 0.12 ENST00000554240.1
SKOR1
SKI family transcriptional corepressor 1
chr8_-_97173020 0.11 ENST00000287020.5
GDF6
growth differentiation factor 6
chr19_-_45996465 0.10 ENST00000430715.2
RTN2
reticulon 2
chr10_-_14996070 0.10 ENST00000378258.1
ENST00000453695.2
ENST00000378246.2
DCLRE1C
DNA cross-link repair 1C
chr19_-_48867291 0.10 ENST00000435956.3
TMEM143
transmembrane protein 143
chr11_+_71791693 0.10 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr8_-_145980968 0.10 ENST00000292562.7
ZNF251
zinc finger protein 251
chr11_-_61197406 0.09 ENST00000541963.1
ENST00000477890.2
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr14_-_50778872 0.06 ENST00000555610.1
ENST00000261699.4
L2HGDH
L-2-hydroxyglutarate dehydrogenase
chr19_-_41196458 0.06 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr18_-_51750948 0.05 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr11_+_89764274 0.05 ENST00000448984.1
ENST00000432771.1
TRIM49C
tripartite motif containing 49C
chr19_+_49588690 0.04 ENST00000221448.5
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr11_+_73019282 0.04 ENST00000263674.3
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr9_-_127533519 0.04 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr16_+_25123041 0.04 ENST00000399069.3
ENST00000380966.4
LCMT1
leucine carboxyl methyltransferase 1
chr19_-_663171 0.04 ENST00000606896.1
ENST00000589762.2
RNF126
ring finger protein 126
chr6_-_166582107 0.03 ENST00000296946.2
ENST00000461348.2
ENST00000366871.3
T
T, brachyury homolog (mouse)
chr7_-_128050027 0.02 ENST00000343214.4
ENST00000354269.5
ENST00000348127.6
ENST00000497868.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr15_-_49447771 0.02 ENST00000558843.1
ENST00000542928.1
ENST00000561248.1
COPS2
COP9 signalosome subunit 2
chr5_+_80597419 0.02 ENST00000254037.2
ENST00000407610.3
ENST00000380199.5
ZCCHC9
zinc finger, CCHC domain containing 9
chr15_-_43622736 0.01 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2
leucine carboxyl methyltransferase 2
chr2_-_74757066 0.01 ENST00000377526.3
AUP1
ancient ubiquitous protein 1
chr19_+_49588677 0.01 ENST00000598984.1
ENST00000598441.1
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)

Network of associatons between targets according to the STRING database.

First level regulatory network of CENPB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0042369 vitamin D catabolic process(GO:0042369)
0.6 2.3 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.5 1.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4 1.3 GO:2000338 interleukin-15 production(GO:0032618) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340)
0.4 1.2 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.3 0.9 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 1.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3 1.8 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 1.7 GO:0015798 myo-inositol transport(GO:0015798)
0.2 0.7 GO:0006481 C-terminal protein methylation(GO:0006481)
0.2 0.7 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.2 1.7 GO:0002353 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.2 5.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 2.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 0.6 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 0.6 GO:1905069 allantois development(GO:1905069)
0.2 1.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 2.4 GO:0007144 female meiosis I(GO:0007144)
0.2 2.3 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 1.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 3.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.4 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.4 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.6 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.7 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 7.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.4 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.9 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.8 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.1 3.0 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.6 GO:0007379 segment specification(GO:0007379)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.5 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 10.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.5 GO:0014002 astrocyte development(GO:0014002)
0.1 0.9 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 2.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.8 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.7 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 1.0 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)
0.0 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 1.1 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.6 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 1.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 1.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 2.6 GO:0014902 myotube differentiation(GO:0014902)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.6 GO:0021510 spinal cord development(GO:0021510)
0.0 0.0 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.0 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.3 GO:0008298 intracellular mRNA localization(GO:0008298)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 1.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.3 1.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 1.6 GO:0071817 MMXD complex(GO:0071817)
0.2 1.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 1.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.5 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 9.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.9 GO:0034709 methylosome(GO:0034709)
0.1 1.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.8 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 2.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 3.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.8 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.9 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 1.7 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 3.6 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.6 1.7 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.5 2.5 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.4 1.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.3 1.0 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.3 2.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 1.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 0.7 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.2 0.6 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 1.6 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 1.8 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2 0.6 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.5 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 1.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 7.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 10.1 GO:0019843 rRNA binding(GO:0019843)
0.1 1.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 2.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.2 GO:0032190 acrosin binding(GO:0032190)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.8 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.7 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 1.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 1.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.6 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 2.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 2.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.9 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.6 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 4.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.8 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 7.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 9.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 2.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 1.7 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor