Project
SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for CUX1
Z-value: 1.63
Motif logo
Transcription factors associated with CUX1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CUX1 | hg19_v2_chr7_+_101459263_101459310 | -0.73 | 2.8e-04 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_153588334 Show fit | 7.08 |
ENST00000476873.1
|
S100 calcium binding protein A14 |
|
| chr1_-_153588765 Show fit | 6.91 |
ENST00000368701.1
ENST00000344616.2 |
S100 calcium binding protein A14 |
|
| chr14_+_21510385 Show fit | 6.21 |
ENST00000298690.4
|
ribonuclease, RNase A family, 7 |
|
| chr2_-_113594279 Show fit | 6.01 |
ENST00000416750.1
ENST00000418817.1 ENST00000263341.2 |
interleukin 1, beta |
|
| chr12_+_7072354 Show fit | 5.93 |
ENST00000537269.1
|
U47924.27 |
|
| chr11_+_35222629 Show fit | 5.86 |
ENST00000526553.1
|
CD44 molecule (Indian blood group) |
|
| chr17_+_7942335 Show fit | 5.49 |
ENST00000380183.4
ENST00000572022.1 ENST00000380173.2 |
arachidonate 15-lipoxygenase, type B |
|
| chr1_+_153003671 Show fit | 4.68 |
ENST00000307098.4
|
small proline-rich protein 1B |
|
| chr1_-_209824643 Show fit | 4.60 |
ENST00000391911.1
ENST00000415782.1 |
laminin, beta 3 |
|
| chr17_+_7341586 Show fit | 4.44 |
ENST00000575235.1
|
fibroblast growth factor 11 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CUX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 14.0 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 1.0 | 12.4 | GO:0070487 | monocyte aggregation(GO:0070487) |
| 1.0 | 8.2 | GO:0051121 | hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
| 0.4 | 7.9 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.2 | 7.4 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.4 | 7.3 | GO:0015816 | glycine transport(GO:0015816) |
| 0.2 | 6.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.4 | 6.5 | GO:0032966 | negative regulation of collagen biosynthetic process(GO:0032966) |
| 1.0 | 6.2 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
| 0.1 | 6.0 | GO:0018149 | peptide cross-linking(GO:0018149) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 15.1 | GO:0016604 | nuclear body(GO:0016604) |
| 0.2 | 11.5 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 8.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 7.7 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 7.0 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.6 | 6.7 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.8 | 6.4 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.2 | 5.4 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 5.3 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 0.1 | 5.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 13.4 | GO:0042379 | chemokine receptor binding(GO:0042379) |
| 0.1 | 12.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 10.0 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 2.1 | 8.2 | GO:0016165 | linoleate 13S-lipoxygenase activity(GO:0016165) |
| 0.5 | 7.3 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.2 | 7.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 7.0 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.4 | 6.2 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.2 | 6.0 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 5.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.4 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.4 | 12.4 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 11.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 9.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.2 | 6.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 5.8 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 4.0 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 3.8 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 3.2 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.1 | 3.1 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.9 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 6.8 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.3 | 6.4 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 5.7 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 5.5 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 4.9 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.3 | 4.7 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 3.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 3.4 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 3.3 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |