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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CUX1

Z-value: 1.63

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Transcription factors associated with CUX1

Gene Symbol Gene ID Gene Info
CUX1
ENSG00000257923.5 cut like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX1hg19_v2_chr7_+_101459263_101459310-0.732.8e-04Click!

Activity profile of CUX1 motif

Sorted Z-values of CUX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153588334 7.08 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr1_-_153588765 6.91 ENST00000368701.1
ENST00000344616.2
S100A14
S100 calcium binding protein A14
chr14_+_21510385 6.21 ENST00000298690.4
RNASE7
ribonuclease, RNase A family, 7
chr2_-_113594279 6.01 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr12_+_7072354 5.93 ENST00000537269.1
U47924.27
U47924.27
chr11_+_35222629 5.86 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr17_+_7942335 5.49 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B
arachidonate 15-lipoxygenase, type B
chr1_+_153003671 4.68 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr1_-_209824643 4.60 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr17_+_7341586 4.44 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr22_-_37640277 4.26 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_-_51472222 4.16 ENST00000376851.3
KLK6
kallikrein-related peptidase 6
chrX_-_48328631 4.16 ENST00000429543.1
ENST00000317669.5
SLC38A5
solute carrier family 38, member 5
chr16_-_31147020 3.97 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr16_+_56659687 3.84 ENST00000568293.1
ENST00000330439.6
MT1E
metallothionein 1E
chr12_-_52845910 3.77 ENST00000252252.3
KRT6B
keratin 6B
chr19_-_51472031 3.70 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chrX_-_48328551 3.55 ENST00000376876.3
SLC38A5
solute carrier family 38, member 5
chr20_-_43883197 3.52 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr1_-_209979465 3.50 ENST00000542854.1
IRF6
interferon regulatory factor 6
chr7_-_143991230 3.47 ENST00000543357.1
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr19_+_35609380 3.43 ENST00000604621.1
FXYD3
FXYD domain containing ion transport regulator 3
chr15_-_75017711 3.29 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr7_-_143892748 3.19 ENST00000378115.2
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr17_-_39681578 3.19 ENST00000593096.1
KRT19
keratin 19
chr7_+_144052381 3.14 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chrX_+_102469997 3.06 ENST00000372695.5
ENST00000372691.3
BEX4
brain expressed, X-linked 4
chr15_-_83953466 2.89 ENST00000345382.2
BNC1
basonuclin 1
chr17_+_7942424 2.87 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr17_-_5487768 2.79 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1
NLR family, pyrin domain containing 1
chr1_+_89829610 2.77 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr14_+_75745477 2.66 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr15_+_43885252 2.65 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr4_-_15939963 2.47 ENST00000259988.2
FGFBP1
fibroblast growth factor binding protein 1
chr3_+_100211412 2.46 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A
transmembrane protein 45A
chr8_-_143867946 2.46 ENST00000301263.4
LY6D
lymphocyte antigen 6 complex, locus D
chr2_+_169923504 2.44 ENST00000357546.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr5_+_147443534 2.41 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr6_+_35310391 2.25 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
PPARD
peroxisome proliferator-activated receptor delta
chr17_+_1665345 2.25 ENST00000576406.1
ENST00000571149.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_-_74533963 2.25 ENST00000293230.5
CYGB
cytoglobin
chr2_+_85804614 2.24 ENST00000263864.5
ENST00000409760.1
VAMP8
vesicle-associated membrane protein 8
chr19_+_5681153 2.22 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr20_-_45142154 2.17 ENST00000347606.4
ENST00000457685.2
ZNF334
zinc finger protein 334
chr19_+_35645817 2.13 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr7_+_73245193 2.11 ENST00000340958.2
CLDN4
claudin 4
chr14_-_24733444 2.09 ENST00000560478.1
ENST00000560443.1
TGM1
transglutaminase 1
chr15_+_43985725 2.09 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr1_-_209792111 2.08 ENST00000455193.1
LAMB3
laminin, beta 3
chr14_-_23623577 2.06 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr2_+_169923577 2.02 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chrX_-_48931648 2.02 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr1_-_207206092 2.01 ENST00000359470.5
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr19_-_36004543 1.99 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr6_+_35310312 1.99 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr16_-_31146961 1.98 ENST00000567531.1
PRSS8
protease, serine, 8
chr17_+_1665253 1.89 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr16_+_68729719 1.89 ENST00000569080.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr16_-_85784634 1.88 ENST00000284245.4
ENST00000602914.1
C16orf74
chromosome 16 open reading frame 74
chr1_-_183560011 1.86 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chrX_+_48367338 1.83 ENST00000359882.4
ENST00000537758.1
ENST00000367574.4
ENST00000355961.4
ENST00000489940.1
ENST00000361988.3
PORCN
porcupine homolog (Drosophila)
chr14_-_24898731 1.75 ENST00000267406.6
CBLN3
cerebellin 3 precursor
chr7_-_127672146 1.70 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr2_-_56150910 1.70 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr1_+_26605618 1.70 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr22_-_31688381 1.69 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr19_-_51530916 1.67 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr19_-_51523412 1.66 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr15_-_42448788 1.65 ENST00000382396.4
ENST00000397272.3
PLA2G4F
phospholipase A2, group IVF
chr6_+_7541808 1.64 ENST00000379802.3
DSP
desmoplakin
chr16_+_55512742 1.64 ENST00000568715.1
ENST00000219070.4
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr20_+_6748311 1.64 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr15_+_43885799 1.63 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr19_-_43032532 1.62 ENST00000403461.1
ENST00000352591.5
ENST00000358394.3
ENST00000403444.3
ENST00000308072.4
ENST00000599389.1
ENST00000351134.3
ENST00000161559.6
CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr18_+_47088401 1.62 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr5_+_178368186 1.61 ENST00000320129.3
ENST00000519564.1
ZNF454
zinc finger protein 454
chr19_-_37406923 1.60 ENST00000520965.1
ZNF829
zinc finger protein 829
chr5_-_154230130 1.60 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chrX_+_135618258 1.58 ENST00000440515.1
ENST00000456412.1
VGLL1
vestigial like 1 (Drosophila)
chr4_-_143226979 1.53 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_+_161676739 1.50 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA
Fc receptor-like A
chr19_-_51523275 1.50 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr17_+_42427826 1.49 ENST00000586443.1
GRN
granulin
chr12_-_57630873 1.49 ENST00000556732.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr8_+_27168988 1.47 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr7_-_3083573 1.45 ENST00000396946.4
CARD11
caspase recruitment domain family, member 11
chr21_+_39628852 1.44 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr9_+_135937365 1.42 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr4_-_143227088 1.40 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_+_24645865 1.39 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_151032040 1.39 ENST00000540998.1
ENST00000357235.5
CDC42SE1
CDC42 small effector 1
chr1_+_9242221 1.39 ENST00000412639.2
RP3-510D11.2
RP3-510D11.2
chr21_+_39668831 1.39 ENST00000419868.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr19_-_10628117 1.39 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr1_+_204797749 1.37 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
NFASC
neurofascin
chr1_+_24646002 1.37 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr12_+_48876275 1.37 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr1_+_24645807 1.37 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr15_+_40532058 1.36 ENST00000260404.4
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr12_-_56121612 1.36 ENST00000546939.1
CD63
CD63 molecule
chr1_+_155100342 1.35 ENST00000368406.2
EFNA1
ephrin-A1
chr8_+_22437664 1.35 ENST00000436754.1
ENST00000426493.1
ENST00000429812.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr21_+_39628655 1.34 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_+_36589547 1.33 ENST00000299440.5
RAG1
recombination activating gene 1
chr16_-_65155979 1.33 ENST00000562325.1
ENST00000268603.4
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr10_+_75670862 1.33 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
PLAU
plasminogen activator, urokinase
chr6_-_75915757 1.30 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr15_+_40531621 1.30 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr6_-_44225231 1.27 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr14_-_24732738 1.26 ENST00000558074.1
ENST00000560226.1
TGM1
transglutaminase 1
chr17_+_1665306 1.25 ENST00000571360.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_+_56477093 1.25 ENST00000549672.1
ENST00000415288.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr19_+_41509851 1.24 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr19_+_35645618 1.22 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr3_+_111717600 1.22 ENST00000273368.4
TAGLN3
transgelin 3
chr1_+_161677034 1.20 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA
Fc receptor-like A
chr12_+_57522258 1.20 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr22_+_41763274 1.19 ENST00000406644.3
TEF
thyrotrophic embryonic factor
chr19_-_58485895 1.16 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr8_+_97506033 1.16 ENST00000518385.1
SDC2
syndecan 2
chr1_+_24645915 1.15 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr3_+_44771088 1.13 ENST00000396048.2
ZNF501
zinc finger protein 501
chr1_-_116383738 1.11 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chrX_+_48916497 1.11 ENST00000496529.2
ENST00000376396.3
ENST00000422185.2
ENST00000603986.1
ENST00000536628.2
CCDC120
coiled-coil domain containing 120
chr6_-_35656712 1.11 ENST00000357266.4
ENST00000542713.1
FKBP5
FK506 binding protein 5
chr5_+_60240943 1.09 ENST00000296597.5
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr16_+_67571351 1.08 ENST00000428437.2
ENST00000569253.1
FAM65A
family with sequence similarity 65, member A
chr4_-_177713788 1.07 ENST00000280193.2
VEGFC
vascular endothelial growth factor C
chr7_-_127671674 1.07 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr11_+_62186498 1.06 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr2_-_31637560 1.06 ENST00000379416.3
XDH
xanthine dehydrogenase
chr1_+_156123359 1.06 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr14_-_21270995 1.06 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr9_-_34376851 1.03 ENST00000297625.7
KIAA1161
KIAA1161
chr11_+_45943169 1.03 ENST00000529052.1
ENST00000531526.1
GYLTL1B
glycosyltransferase-like 1B
chr6_+_87865262 1.02 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr19_+_20011775 1.02 ENST00000592245.1
ENST00000592160.1
ENST00000343769.5
AC007204.2
ZNF93
AC007204.2
zinc finger protein 93
chr3_+_9944492 1.01 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
IL17RE
interleukin 17 receptor E
chr2_-_85636928 1.01 ENST00000449030.1
CAPG
capping protein (actin filament), gelsolin-like
chr1_+_1846519 1.00 ENST00000378604.3
CALML6
calmodulin-like 6
chr7_+_75932863 0.99 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr8_+_97597148 0.99 ENST00000521590.1
SDC2
syndecan 2
chr8_+_107282368 0.99 ENST00000521369.2
RP11-395G23.3
RP11-395G23.3
chr8_-_133687813 0.98 ENST00000250173.1
ENST00000519595.1
LRRC6
leucine rich repeat containing 6
chr6_+_31926857 0.97 ENST00000375394.2
ENST00000544581.1
SKIV2L
superkiller viralicidic activity 2-like (S. cerevisiae)
chr10_-_105421427 0.97 ENST00000538130.1
SH3PXD2A
SH3 and PX domains 2A
chr9_+_33795533 0.97 ENST00000379405.3
PRSS3
protease, serine, 3
chr5_+_40841276 0.96 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr5_-_142065223 0.96 ENST00000378046.1
FGF1
fibroblast growth factor 1 (acidic)
chr19_-_14629224 0.96 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr10_-_105437909 0.95 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr12_+_128399965 0.95 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr11_-_94965667 0.95 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr14_-_21737610 0.94 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr1_+_152758690 0.93 ENST00000368771.1
ENST00000368770.3
LCE1E
late cornified envelope 1E
chr19_+_10197463 0.93 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr19_+_44556158 0.93 ENST00000434772.3
ENST00000585552.1
ZNF223
zinc finger protein 223
chr19_-_5680891 0.92 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr17_-_47865948 0.92 ENST00000513602.1
FAM117A
family with sequence similarity 117, member A
chr14_+_61995722 0.92 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr8_+_22435762 0.91 ENST00000456545.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr2_-_232329186 0.91 ENST00000322723.4
NCL
nucleolin
chr12_-_56753858 0.90 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr12_-_56121580 0.89 ENST00000550776.1
CD63
CD63 molecule
chr11_+_46299199 0.89 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chrX_+_153059608 0.89 ENST00000370087.1
SSR4
signal sequence receptor, delta
chr1_+_2487631 0.88 ENST00000409119.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr1_+_17531614 0.88 ENST00000375471.4
PADI1
peptidyl arginine deiminase, type I
chr13_+_103451548 0.88 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr1_-_204116078 0.88 ENST00000367198.2
ENST00000452983.1
ETNK2
ethanolamine kinase 2
chr3_-_48601206 0.86 ENST00000273610.3
UCN2
urocortin 2
chr15_-_70390213 0.86 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr7_+_116451100 0.85 ENST00000464223.1
ENST00000484325.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr3_+_136649311 0.85 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr1_+_46668994 0.85 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr1_+_156119798 0.84 ENST00000355014.2
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_-_29600832 0.84 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr15_+_74908147 0.84 ENST00000568139.1
ENST00000563297.1
ENST00000568488.1
ENST00000352989.5
ENST00000348245.3
CLK3
CDC-like kinase 3
chr1_+_206730484 0.84 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr5_+_176784837 0.83 ENST00000408923.3
RGS14
regulator of G-protein signaling 14
chr4_-_140544386 0.83 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr11_+_111412271 0.83 ENST00000528102.1
LAYN
layilin
chr10_+_24755416 0.82 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr20_-_17641097 0.82 ENST00000246043.4
RRBP1
ribosome binding protein 1
chr3_-_99569821 0.82 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr19_-_12267524 0.81 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
ZNF625
zinc finger protein 625
chr17_+_38171614 0.81 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr15_-_43882353 0.81 ENST00000453080.1
ENST00000360301.4
ENST00000360135.4
ENST00000417085.1
ENST00000431962.1
ENST00000334933.4
ENST00000381879.4
ENST00000420765.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_-_112281875 0.80 ENST00000527621.1
ENST00000534365.1
ENST00000357260.5
FAM212B
family with sequence similarity 212, member B
chr4_-_103749205 0.80 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr21_-_34915084 0.79 ENST00000426819.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr5_+_38445641 0.79 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr11_+_65343494 0.79 ENST00000309295.4
ENST00000533237.1
EHBP1L1
EH domain binding protein 1-like 1
chr20_+_18269121 0.78 ENST00000377671.3
ENST00000360010.5
ENST00000396026.3
ENST00000402618.2
ENST00000401790.1
ENST00000434018.1
ENST00000538547.1
ENST00000535822.1
ZNF133
zinc finger protein 133
chr19_-_12889226 0.78 ENST00000589400.1
ENST00000590839.1
ENST00000592079.1
HOOK2
hook microtubule-tethering protein 2
chr14_-_67982146 0.78 ENST00000557779.1
ENST00000557006.1
TMEM229B
transmembrane protein 229B
chr17_+_18280976 0.77 ENST00000399134.4
EVPLL
envoplakin-like
chr18_+_11752040 0.77 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr17_+_6915798 0.76 ENST00000402093.1
RNASEK
ribonuclease, RNase K
chr19_+_5681011 0.76 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.1 3.3 GO:0043449 cellular alkene metabolic process(GO:0043449)
1.0 6.2 GO:0051673 membrane disruption in other organism(GO:0051673)
1.0 12.4 GO:0070487 monocyte aggregation(GO:0070487)
1.0 8.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.9 2.8 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.8 5.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.7 2.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.6 14.0 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.5 1.6 GO:0060129 regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.5 1.6 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.5 5.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.5 3.4 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.5 1.9 GO:0032771 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.4 4.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 1.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 1.3 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.4 6.5 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.4 1.6 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.4 7.3 GO:0015816 glycine transport(GO:0015816)
0.4 2.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.4 7.9 GO:0016540 protein autoprocessing(GO:0016540)
0.4 2.5 GO:0008218 bioluminescence(GO:0008218)
0.4 1.8 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 2.4 GO:1900425 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) negative regulation of defense response to bacterium(GO:1900425)
0.3 1.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 3.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.3 2.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 1.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.3 0.8 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.3 1.4 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.3 1.9 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 1.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 1.0 GO:0070893 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.2 1.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.2 7.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 1.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 2.7 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.2 0.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 1.5 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 5.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 0.6 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 0.6 GO:1901656 glycoside transport(GO:1901656)
0.2 1.8 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.2 1.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 2.4 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 6.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.1 GO:0010193 response to ozone(GO:0010193)
0.2 0.9 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 0.5 GO:0018874 benzoate metabolic process(GO:0018874)
0.2 1.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 0.7 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.2 2.5 GO:0035634 response to stilbenoid(GO:0035634)
0.2 1.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 1.6 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.2 1.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 1.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.9 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 0.3 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 2.5 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.7 GO:0015748 organophosphate ester transport(GO:0015748) phospholipid transport(GO:0015914)
0.1 0.7 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.3 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 0.7 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.7 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 0.4 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.1 0.6 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.4 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 1.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 3.7 GO:0007398 ectoderm development(GO:0007398)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.7 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.3 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 2.7 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.4 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 3.5 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 2.0 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 1.7 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 1.7 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.6 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 3.5 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.8 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.2 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 3.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 3.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.9 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.3 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.1 1.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.4 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 1.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.5 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 6.0 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 5.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 0.2 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.0 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 1.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 1.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 3.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.4 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.1 0.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.7 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.5 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.4 GO:0072221 metanephric part of ureteric bud development(GO:0035502) distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.1 0.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 3.3 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 1.7 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 1.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.9 GO:0015695 organic cation transport(GO:0015695)
0.1 0.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.8 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.5 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 1.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.4 GO:1902572 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 1.8 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.8 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0046041 ITP metabolic process(GO:0046041)
0.0 1.2 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 1.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.8 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.8 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.3 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 2.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:0051495 positive regulation of cytoskeleton organization(GO:0051495)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 2.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.2 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.2 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 1.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.3 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.5 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:0070997 neuron death(GO:0070997)
0.0 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:1905229 thyroid-stimulating hormone signaling pathway(GO:0038194) cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 1.1 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.7 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 1.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.8 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.8 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.6 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.3 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 2.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.7 GO:0043067 regulation of programmed cell death(GO:0043067)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.7 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.0 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0048565 digestive tract development(GO:0048565)
0.0 0.3 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.1 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.2 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122)
0.0 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.6 6.7 GO:0005610 laminin-5 complex(GO:0005610)
0.4 1.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.4 3.2 GO:1990357 terminal web(GO:1990357)
0.4 2.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.3 2.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 0.9 GO:0097444 spine apparatus(GO:0097444)
0.3 1.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 2.7 GO:0035976 AP1 complex(GO:0035976)
0.3 1.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 1.0 GO:0055087 Ski complex(GO:0055087)
0.2 5.4 GO:0043203 axon hillock(GO:0043203)
0.2 0.6 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 2.0 GO:0032010 phagolysosome(GO:0032010)
0.2 1.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 2.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 1.2 GO:1902560 GMP reductase complex(GO:1902560)
0.2 11.5 GO:0001533 cornified envelope(GO:0001533)
0.1 8.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.4 GO:1990923 PET complex(GO:1990923)
0.1 0.8 GO:0070695 FHF complex(GO:0070695)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.9 GO:0061574 ASAP complex(GO:0061574)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 5.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0000346 transcription export complex(GO:0000346)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 7.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 4.6 GO:0002102 podosome(GO:0002102)
0.1 0.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 7.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.1 GO:0045095 keratin filament(GO:0045095)
0.0 2.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.7 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 15.1 GO:0016604 nuclear body(GO:0016604)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 5.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.7 3.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.6 1.8 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.6 1.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.6 2.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.5 2.9 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.5 7.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 1.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.4 6.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.4 1.6 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.3 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3 4.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 1.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.2 1.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 1.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 1.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 1.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 6.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 3.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 13.4 GO:0042379 chemokine receptor binding(GO:0042379)
0.2 3.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.6 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 0.9 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 4.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.1 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 7.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.4 GO:0004771 sterol esterase activity(GO:0004771)
0.2 0.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 1.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 2.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 0.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 1.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 0.7 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.2 2.1 GO:0019534 toxin transporter activity(GO:0019534)
0.2 1.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.7 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.6 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.6 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 1.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 1.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0005055 laminin receptor activity(GO:0005055)
0.1 3.6 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 0.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 1.0 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.5 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 2.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 10.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 1.6 GO:0019211 phosphatase activator activity(GO:0019211) BMP receptor binding(GO:0070700)
0.1 0.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 1.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.6 GO:0050733 RS domain binding(GO:0050733)
0.1 1.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.2 GO:0038132 neuregulin binding(GO:0038132)
0.1 2.1 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.7 GO:0030172 troponin C binding(GO:0030172)
0.1 0.4 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 1.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.6 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.2 GO:0097689 iron channel activity(GO:0097689)
0.1 12.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.9 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 0.7 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 0.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 2.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.4 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.3 GO:0010736 serum response element binding(GO:0010736)
0.1 0.2 GO:0019961 interferon binding(GO:0019961)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 1.2 GO:0051400 BH domain binding(GO:0051400)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 2.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.7 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 4.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 1.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.4 GO:0035326 enhancer binding(GO:0035326)
0.0 0.6 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 5.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 1.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 1.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 5.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 7.0 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 4.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 3.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.0 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 6.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 9.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 5.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.9 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 3.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 3.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 22.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 3.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 11.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 3.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.3 6.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 5.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 6.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 3.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 11.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 4.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 2.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.5 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.7 REACTOME PURINE METABOLISM Genes involved in Purine metabolism
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 3.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 5.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins