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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DLX3_EVX1_MEOX1

Z-value: 0.44

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Transcription factors associated with DLX3_EVX1_MEOX1

Gene Symbol Gene ID Gene Info
DLX3
ENSG00000064195.7 distal-less homeobox 3
EVX1
ENSG00000106038.8 even-skipped homeobox 1
MEOX1
ENSG00000005102.8 mesenchyme homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX3hg19_v2_chr17_-_48072574_48072597-0.697.5e-04Click!
MEOX1hg19_v2_chr17_-_41739283_41739322-0.321.7e-01Click!
EVX1hg19_v2_chr7_+_27282319_272823940.174.8e-01Click!

Activity profile of DLX3_EVX1_MEOX1 motif

Sorted Z-values of DLX3_EVX1_MEOX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_59910132 1.52 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr7_-_14029283 1.18 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr6_+_151646800 1.16 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr9_+_116225999 0.97 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr15_+_80351910 0.94 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr15_-_64673630 0.92 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr17_-_33446735 0.88 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr20_+_60174827 0.85 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr17_-_33446820 0.82 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr17_-_46690839 0.81 ENST00000498634.2
HOXB8
homeobox B8
chr15_-_64673665 0.78 ENST00000300035.4
KIAA0101
KIAA0101
chr16_-_29910853 0.74 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr6_-_76203454 0.73 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr7_-_99716940 0.73 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_-_31531121 0.73 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr7_+_6655225 0.71 ENST00000457543.3
ZNF853
zinc finger protein 853
chr6_-_76203345 0.70 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr3_+_44840679 0.69 ENST00000425755.1
KIF15
kinesin family member 15
chr17_-_57229155 0.67 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr17_-_46716647 0.63 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr1_-_21625486 0.62 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr5_-_159827033 0.62 ENST00000523213.1
C5orf54
chromosome 5 open reading frame 54
chr16_+_53133070 0.62 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr8_+_40010989 0.61 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr10_-_92681033 0.60 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr7_-_32338917 0.58 ENST00000396193.1
PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr20_+_43029911 0.58 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr11_+_47293795 0.57 ENST00000422579.1
MADD
MAP-kinase activating death domain
chr4_-_139163491 0.57 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr7_-_33102399 0.57 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr7_-_33102338 0.56 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr12_+_107712173 0.56 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chrX_-_106243294 0.54 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr5_+_174151536 0.54 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr15_-_37393406 0.54 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr15_+_89631647 0.53 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr15_-_55562582 0.53 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr7_-_99716952 0.52 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr15_+_89631381 0.52 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr14_-_95236551 0.51 ENST00000238558.3
GSC
goosecoid homeobox
chr5_+_156712372 0.51 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr12_-_120241187 0.49 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr12_-_56694083 0.49 ENST00000552688.1
ENST00000548041.1
ENST00000551137.1
ENST00000551968.1
ENST00000542324.2
ENST00000546930.1
ENST00000549221.1
ENST00000550159.1
ENST00000550734.1
CS
citrate synthase
chr6_+_126221034 0.48 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr1_-_197115818 0.48 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr1_-_232651312 0.48 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr12_+_78359999 0.47 ENST00000550503.1
NAV3
neuron navigator 3
chr15_-_55563072 0.47 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr14_-_37051798 0.46 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr1_-_159832438 0.46 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr16_+_57844549 0.46 ENST00000564282.1
CTD-2600O9.1
uncharacterized protein LOC388282
chr17_-_64225508 0.45 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr17_+_43238438 0.45 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chrX_-_106243451 0.44 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr4_+_105828537 0.43 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr11_-_117747327 0.42 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr2_-_61697862 0.41 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr14_-_57960545 0.41 ENST00000526336.1
ENST00000216445.3
C14orf105
chromosome 14 open reading frame 105
chr4_+_41614909 0.41 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr14_-_57960456 0.41 ENST00000534126.1
ENST00000422976.2
C14orf105
chromosome 14 open reading frame 105
chr7_-_14029515 0.41 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr12_+_28410128 0.41 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr8_+_22424551 0.41 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr7_-_111424506 0.40 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr20_-_50419055 0.40 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr8_-_19614810 0.39 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr6_+_142623758 0.39 ENST00000541199.1
ENST00000435011.2
GPR126
G protein-coupled receptor 126
chr13_+_78315466 0.39 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr14_+_67831576 0.39 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chrX_+_10031499 0.37 ENST00000454666.1
WWC3
WWC family member 3
chr5_+_159343688 0.37 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr20_+_42187682 0.36 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr12_-_56693758 0.36 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
CS
citrate synthase
chr15_-_65903407 0.35 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9
von Willebrand factor A domain containing 9
chr8_+_32579271 0.34 ENST00000518084.1
NRG1
neuregulin 1
chr6_+_105404899 0.33 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr7_-_99717463 0.33 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_+_41614720 0.32 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr8_+_32579341 0.32 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr8_+_32579321 0.31 ENST00000522402.1
NRG1
neuregulin 1
chr15_+_89164560 0.31 ENST00000379231.3
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr22_-_30960876 0.31 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr12_+_54378849 0.30 ENST00000515593.1
HOXC10
homeobox C10
chr10_-_33623310 0.29 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr10_-_27529486 0.29 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr20_+_43990576 0.29 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr7_-_111424462 0.29 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr7_-_14028488 0.29 ENST00000405358.4
ETV1
ets variant 1
chr12_+_54378923 0.28 ENST00000303460.4
HOXC10
homeobox C10
chr6_-_116833500 0.28 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr13_-_31191642 0.28 ENST00000405805.1
HMGB1
high mobility group box 1
chr10_+_35484793 0.28 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr13_-_30160925 0.28 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_+_34287751 0.28 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr3_-_123339343 0.27 ENST00000578202.1
MYLK
myosin light chain kinase
chr20_+_3776371 0.27 ENST00000245960.5
CDC25B
cell division cycle 25B
chr16_+_57139933 0.27 ENST00000566259.1
CPNE2
copine II
chrX_-_19689106 0.26 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr10_-_101690650 0.26 ENST00000543621.1
DNMBP
dynamin binding protein
chr20_+_42187608 0.26 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr3_-_33686925 0.25 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr13_+_36050881 0.24 ENST00000537702.1
NBEA
neurobeachin
chr17_+_73539339 0.24 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr5_+_137722255 0.24 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr18_+_32556892 0.24 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr15_+_80351977 0.23 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr6_+_52535878 0.23 ENST00000211314.4
TMEM14A
transmembrane protein 14A
chr8_-_17533838 0.23 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr17_+_42264556 0.23 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr2_-_55647057 0.23 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr5_-_142780280 0.22 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_-_105416039 0.22 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr4_+_66536248 0.22 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr12_-_15815626 0.22 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr13_+_78315528 0.21 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr2_-_55646957 0.21 ENST00000263630.8
CCDC88A
coiled-coil domain containing 88A
chr1_+_202317855 0.20 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr15_-_55562479 0.20 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr2_+_113299990 0.20 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr4_-_174451370 0.20 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr17_-_48785216 0.20 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr7_+_116660246 0.20 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr11_+_101918153 0.20 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr12_-_56694142 0.19 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr15_+_75080883 0.19 ENST00000567571.1
CSK
c-src tyrosine kinase
chr20_-_50418972 0.19 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr8_-_1922789 0.19 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr11_-_124981475 0.19 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chr4_-_155533787 0.19 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr1_-_190446759 0.19 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr16_-_66864806 0.19 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr6_-_76072719 0.18 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chrX_-_46187069 0.18 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr16_-_69390209 0.18 ENST00000563634.1
RP11-343C2.9
Uncharacterized protein
chr4_-_66536057 0.18 ENST00000273854.3
EPHA5
EPH receptor A5
chr3_-_33686743 0.18 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr6_-_111804905 0.18 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr14_+_74034310 0.18 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr18_-_44181442 0.18 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr13_+_78315295 0.18 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr2_-_37544209 0.18 ENST00000234179.2
PRKD3
protein kinase D3
chr4_-_66536196 0.17 ENST00000511294.1
EPHA5
EPH receptor A5
chr4_-_138453606 0.17 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr6_-_75994025 0.17 ENST00000518161.1
TMEM30A
transmembrane protein 30A
chr3_+_159557637 0.17 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr4_+_95916947 0.17 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr17_-_2117600 0.17 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr6_-_111136299 0.17 ENST00000457688.1
CDK19
cyclin-dependent kinase 19
chr4_+_105828492 0.16 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr2_-_17981462 0.16 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr5_-_87516448 0.16 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chrX_-_72434628 0.16 ENST00000536638.1
ENST00000373517.3
NAP1L2
nucleosome assembly protein 1-like 2
chr2_-_224467002 0.16 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr13_-_45010939 0.16 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr6_+_127898312 0.16 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr12_-_53171128 0.15 ENST00000332411.2
KRT76
keratin 76
chr10_-_21186144 0.15 ENST00000377119.1
NEBL
nebulette
chr14_-_51027838 0.15 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr8_+_110346546 0.15 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chr20_-_271304 0.15 ENST00000400269.3
ENST00000360321.2
C20orf96
chromosome 20 open reading frame 96
chr19_-_45681482 0.15 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A
trafficking protein particle complex 6A
chr20_+_18447771 0.15 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr8_-_101963482 0.15 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_-_86422095 0.15 ENST00000254636.5
IMMT
inner membrane protein, mitochondrial
chr3_-_57233966 0.14 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr14_+_56584414 0.14 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr17_-_71223839 0.14 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr6_+_4087664 0.14 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr9_+_130026756 0.13 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr5_-_16509101 0.13 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr17_-_1418972 0.13 ENST00000571274.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr15_+_89164520 0.13 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr11_-_47546220 0.13 ENST00000528538.1
CELF1
CUGBP, Elav-like family member 1
chr8_-_110346614 0.13 ENST00000239690.4
NUDCD1
NudC domain containing 1
chr18_-_56985873 0.13 ENST00000299721.3
CPLX4
complexin 4
chr12_+_64798826 0.13 ENST00000540203.1
XPOT
exportin, tRNA
chr1_+_101003687 0.13 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr6_-_111136513 0.13 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr9_-_34329198 0.13 ENST00000379166.2
ENST00000345050.2
KIF24
kinesin family member 24
chr1_-_219615984 0.13 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr4_+_146402346 0.12 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr17_+_44679808 0.12 ENST00000571172.1
NSF
N-ethylmaleimide-sensitive factor
chr12_-_10978957 0.12 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr17_-_38956205 0.12 ENST00000306658.7
KRT28
keratin 28
chr13_+_78315348 0.12 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr7_+_99717230 0.12 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr13_-_28545276 0.12 ENST00000381020.7
CDX2
caudal type homeobox 2
chr1_-_243326612 0.12 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr9_+_82188077 0.12 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_-_27498208 0.11 ENST00000424577.1
ENST00000426569.1
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr13_+_110958124 0.11 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr20_-_50418947 0.11 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr9_-_136933134 0.11 ENST00000303407.7
BRD3
bromodomain containing 3
chr8_-_101963677 0.11 ENST00000395956.3
ENST00000395953.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr11_-_117747434 0.11 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr2_-_99279928 0.11 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr5_-_148929848 0.11 ENST00000504676.1
ENST00000515435.1
CSNK1A1
casein kinase 1, alpha 1
chr2_+_201754135 0.11 ENST00000409357.1
ENST00000409129.2
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr1_+_236958554 0.10 ENST00000366577.5
ENST00000418145.2
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chr11_-_95657231 0.10 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2
myotubularin related protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX3_EVX1_MEOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 1.7 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 0.5 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 0.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 1.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 1.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.0 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.6 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.4 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.7 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.3 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 2.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.3 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.4 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 1.2 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 1.0 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.8 GO:0007625 grooming behavior(GO:0007625)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 1.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701) bone marrow development(GO:0048539)
0.0 0.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0007019 microtubule depolymerization(GO:0007019)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.7 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 0.7 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.4 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 0.6 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 1.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.3 1.0 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.2 1.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.7 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.7 GO:0000150 recombinase activity(GO:0000150)
0.1 1.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.4 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 1.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.4 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0035877 death effector domain binding(GO:0035877) cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors