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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DRGX_PROP1

Z-value: 0.80

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Transcription factors associated with DRGX_PROP1

Gene Symbol Gene ID Gene Info
ENSG00000165606.4 dorsal root ganglia homeobox
ENSG00000175325.2 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DRGXhg19_v2_chr10_-_50603497_506034970.184.4e-01Click!

Activity profile of DRGX_PROP1 motif

Sorted Z-values of DRGX_PROP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_155484103 4.71 ENST00000302068.4
fibrinogen beta chain
chr4_+_155484155 4.64 ENST00000509493.1
fibrinogen beta chain
chr6_-_32908792 2.92 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr14_-_95236551 2.86 ENST00000238558.3
goosecoid homeobox
chr18_+_20714525 2.71 ENST00000400473.2
Cdk5 and Abl enzyme substrate 1
chr8_-_95229531 2.60 ENST00000450165.2
cadherin 17, LI cadherin (liver-intestine)
chr5_+_142149955 2.23 ENST00000378004.3
Rho GTPase activating protein 26
chr4_+_48485341 2.10 ENST00000273861.4
solute carrier family 10, member 4
chr6_-_32908765 2.09 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr3_+_149191723 2.05 ENST00000305354.4
transmembrane 4 L six family member 4
chr6_-_107235331 2.01 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
chr3_+_149192475 2.00 ENST00000465758.1
transmembrane 4 L six family member 4
chr3_-_157824292 1.90 ENST00000483851.2
short stature homeobox 2
chr6_-_76072719 1.87 ENST00000370020.1
filamin A interacting protein 1
chr16_+_81272287 1.67 ENST00000425577.2
ENST00000564552.1
beta-carotene 15,15'-monooxygenase 1
chr7_-_107883678 1.67 ENST00000417701.1
neuronal cell adhesion molecule
chr5_+_142149932 1.63 ENST00000274498.4
Rho GTPase activating protein 26
chr3_-_27764190 1.57 ENST00000537516.1
eomesodermin
chr3_+_159943362 1.55 ENST00000326474.3
chromosome 3 open reading frame 80
chr6_-_107235378 1.53 ENST00000606430.1
RP1-60O19.1
chr12_+_54410664 1.47 ENST00000303406.4
homeobox C4
chr10_+_89420706 1.43 ENST00000427144.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_-_58468437 1.43 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
Fanconi anemia, complementation group L
chr8_-_17752996 1.41 ENST00000381841.2
ENST00000427924.1
fibrinogen-like 1
chr6_-_107235287 1.41 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
chr8_-_17752912 1.36 ENST00000398054.1
ENST00000381840.2
fibrinogen-like 1
chr12_+_54422142 1.34 ENST00000243108.4
homeobox C6
chr3_-_27763803 1.28 ENST00000449599.1
eomesodermin
chr1_+_42846443 1.25 ENST00000410070.2
ENST00000431473.3
ribosomal modification protein rimK-like family member A
chrX_+_77166172 1.25 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chrX_-_55208866 1.24 ENST00000545075.1
MT-RNR2-like 10
chr6_-_24358264 1.24 ENST00000378454.3
doublecortin domain containing 2
chrX_+_108779004 1.23 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr5_-_87516448 1.11 ENST00000511218.1
transmembrane protein 161B
chr22_-_43398442 1.11 ENST00000422336.1
protein kinase C and casein kinase substrate in neurons 2
chr12_+_58003935 1.10 ENST00000333972.7
Rho guanine nucleotide exchange factor (GEF) 25
chr1_-_92371839 1.07 ENST00000370399.2
transforming growth factor, beta receptor III
chr15_+_75628394 1.05 ENST00000564815.1
ENST00000338995.6
COMM domain containing 4
chr19_-_11456872 1.00 ENST00000586218.1
transmembrane protein 205
chr9_-_39239171 0.98 ENST00000358144.2
contactin associated protein-like 3
chr15_+_75628232 0.98 ENST00000267935.8
ENST00000567195.1
COMM domain containing 4
chr2_+_152214098 0.91 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr22_-_30642728 0.90 ENST00000403987.3
leukemia inhibitory factor
chr19_-_11456905 0.90 ENST00000588560.1
ENST00000592952.1
transmembrane protein 205
chr5_-_59783882 0.90 ENST00000505507.2
ENST00000502484.2
phosphodiesterase 4D, cAMP-specific
chr12_-_118796910 0.87 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr6_+_26087646 0.84 ENST00000309234.6
hemochromatosis
chr1_-_200379180 0.83 ENST00000294740.3
zinc finger protein 281
chrX_+_119737806 0.80 ENST00000371317.5
malignant T cell amplified sequence 1
chr12_-_118796971 0.79 ENST00000542902.1
TAO kinase 3
chr4_+_142558078 0.78 ENST00000529613.1
interleukin 15
chr7_-_111032971 0.76 ENST00000450877.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr2_+_75873902 0.75 ENST00000393909.2
ENST00000358788.6
ENST00000409374.1
mitochondrial ribosomal protein L19
chr6_+_3259122 0.75 ENST00000438998.2
ENST00000380305.4
proteasome (prosome, macropain) assembly chaperone 4
chr2_+_29001711 0.71 ENST00000418910.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr2_-_70529126 0.71 ENST00000438759.1
ENST00000430566.1
family with sequence similarity 136, member A
chr17_+_74463650 0.69 ENST00000392492.3
aralkylamine N-acetyltransferase
chr2_-_145275228 0.68 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
zinc finger E-box binding homeobox 2
chr2_+_101437487 0.68 ENST00000427413.1
ENST00000542504.1
neuronal PAS domain protein 2
chr2_+_44502630 0.67 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
solute carrier family 3 (amino acid transporter heavy chain), member 1
chrX_-_19817869 0.66 ENST00000379698.4
SH3-domain kinase binding protein 1
chr2_+_44502597 0.66 ENST00000260649.6
ENST00000409387.1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr14_-_75536182 0.65 ENST00000555463.1
acylphosphatase 1, erythrocyte (common) type
chr17_+_71228740 0.65 ENST00000268942.8
ENST00000359042.2
chromosome 17 open reading frame 80
chr10_+_69865866 0.64 ENST00000354393.2
myopalladin
chr12_-_15815626 0.63 ENST00000540613.1
epidermal growth factor receptor pathway substrate 8
chr3_-_87325612 0.63 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU class 1 homeobox 1
chr2_-_55496174 0.62 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr3_+_138340067 0.61 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr17_-_39023462 0.60 ENST00000251643.4
keratin 12
chr6_+_3259148 0.59 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome (prosome, macropain) assembly chaperone 4
chr2_-_70529180 0.59 ENST00000450256.1
ENST00000037869.3
family with sequence similarity 136, member A
chr11_+_85359002 0.59 ENST00000528105.1
ENST00000304511.2
transmembrane protein 126A
chrX_+_18725758 0.58 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr11_+_8040739 0.58 ENST00000534099.1
tubby bipartite transcription factor
chr3_+_12392971 0.57 ENST00000287820.6
peroxisome proliferator-activated receptor gamma
chr1_+_170115142 0.56 ENST00000439373.2
methyltransferase like 11B
chr1_+_170632250 0.55 ENST00000367760.3
paired related homeobox 1
chr19_-_11456722 0.55 ENST00000354882.5
transmembrane protein 205
chr19_-_11456935 0.55 ENST00000590788.1
ENST00000586590.1
ENST00000589555.1
ENST00000586956.1
ENST00000593256.2
ENST00000447337.1
ENST00000591677.1
ENST00000586701.1
ENST00000589655.1
transmembrane protein 205
RAB3D, member RAS oncogene family
chr3_-_191000172 0.55 ENST00000427544.2
urotensin 2B
chr5_+_61874562 0.54 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr1_+_244214577 0.54 ENST00000358704.4
zinc finger and BTB domain containing 18
chr3_+_111393501 0.53 ENST00000393934.3
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr12_+_72080253 0.53 ENST00000549735.1
transmembrane protein 19
chr22_-_29107919 0.53 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr9_+_123884038 0.53 ENST00000373847.1
centriolin
chr13_-_88463487 0.52 ENST00000606221.1
RP11-471M2.3
chr11_+_85359062 0.50 ENST00000532180.1
transmembrane protein 126A
chr6_+_27791862 0.50 ENST00000355057.1
histone cluster 1, H4j
chr10_+_695888 0.50 ENST00000441152.2
proline rich 26
chr2_-_145278475 0.50 ENST00000558170.2
zinc finger E-box binding homeobox 2
chr17_-_5321549 0.49 ENST00000572809.1
nucleoporin 88kDa
chr14_+_67831576 0.48 ENST00000555876.1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr4_+_95916947 0.47 ENST00000506363.1
bone morphogenetic protein receptor, type IB
chr15_+_48483736 0.46 ENST00000417307.2
ENST00000559641.1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr10_+_115312766 0.46 ENST00000351270.3
hyaluronan binding protein 2
chr6_-_150067696 0.46 ENST00000340413.2
ENST00000367403.3
nucleoporin 43kDa
chr1_-_241799232 0.45 ENST00000366553.1
choroideremia-like (Rab escort protein 2)
chr2_+_32390925 0.45 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
solute carrier family 30 (zinc transporter), member 6
chr5_+_140514782 0.45 ENST00000231134.5
protocadherin beta 5
chr18_-_2982869 0.44 ENST00000584915.1
lipin 2
chr2_+_128458514 0.44 ENST00000310981.4
SFT2 domain containing 3
chr12_-_110883346 0.43 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr12_-_52946923 0.43 ENST00000267119.5
keratin 71
chr3_+_153839149 0.43 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr14_-_81425828 0.41 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
centrosomal protein 128kDa
chr19_+_54619125 0.41 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
pre-mRNA processing factor 31
chr4_+_88571429 0.41 ENST00000339673.6
ENST00000282479.7
dentin matrix acidic phosphoprotein 1
chr6_-_27835357 0.41 ENST00000331442.3
histone cluster 1, H1b
chr16_-_69373396 0.40 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
component of oligomeric golgi complex 8
chr13_+_53602894 0.39 ENST00000219022.2
olfactomedin 4
chr3_-_156878482 0.39 ENST00000295925.4
cyclin L1
chr2_+_109237717 0.38 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr2_-_145275828 0.37 ENST00000392861.2
ENST00000409211.1
zinc finger E-box binding homeobox 2
chr1_+_62439037 0.37 ENST00000545929.1
InaD-like (Drosophila)
chr1_-_232651312 0.37 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr10_+_18689637 0.36 ENST00000377315.4
calcium channel, voltage-dependent, beta 2 subunit
chr14_+_38065052 0.36 ENST00000556845.1
tetratricopeptide repeat domain 6
chr8_-_62602327 0.36 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
aspartate beta-hydroxylase
chr22_-_30953587 0.36 ENST00000453479.1
galactose-3-O-sulfotransferase 1
chr13_+_88325498 0.35 ENST00000400028.3
SLIT and NTRK-like family, member 5
chr12_+_100897130 0.35 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
nuclear receptor subfamily 1, group H, member 4
chr11_+_108094786 0.35 ENST00000601453.1
ataxia telangiectasia mutated
chr3_-_11623804 0.33 ENST00000451674.2
vestigial like 4 (Drosophila)
chr1_+_12976450 0.33 ENST00000361079.2
PRAME family member 7
chr2_-_55237484 0.33 ENST00000394609.2
reticulon 4
chr17_-_71228357 0.33 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
family with sequence similarity 104, member A
chr13_-_47471155 0.33 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr9_-_70465758 0.32 ENST00000489273.1
COBW domain containing 5
chr4_+_113568207 0.32 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr16_+_89334512 0.32 ENST00000602042.1
AC137932.1
chr11_-_58035732 0.32 ENST00000395079.2
olfactory receptor, family 10, subfamily W, member 1
chr4_-_89951028 0.32 ENST00000506913.1
family with sequence similarity 13, member A
chr6_-_111804905 0.31 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr18_-_44181442 0.31 ENST00000398722.4
lipoxygenase homology domains 1
chr10_+_35464513 0.31 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
cAMP responsive element modulator
chr9_+_88556444 0.31 ENST00000376040.1
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr9_+_42671887 0.30 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr5_+_61874696 0.30 ENST00000491184.2
leucine rich repeat containing 70
chr5_+_140480083 0.30 ENST00000231130.2
protocadherin beta 3
chr5_+_68860949 0.30 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr1_-_151148442 0.30 ENST00000441701.1
ENST00000416280.2
tropomodulin 4 (muscle)
chr17_+_41150290 0.30 ENST00000589037.1
ENST00000253788.5
ribosomal protein L27
chr2_-_183291741 0.30 ENST00000351439.5
ENST00000409365.1
phosphodiesterase 1A, calmodulin-dependent
chr11_-_40315640 0.29 ENST00000278198.2
leucine rich repeat containing 4C
chr1_+_50459990 0.29 ENST00000448346.1
AL645730.2
chr19_+_13842559 0.29 ENST00000586600.1
coiled-coil domain containing 130
chr7_+_93535817 0.29 ENST00000248572.5
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr19_+_47616682 0.28 ENST00000594526.1
SUMO1 activating enzyme subunit 1
chr1_-_242162375 0.28 ENST00000357246.3
microtubule-associated protein 1 light chain 3 gamma
chrX_+_10126488 0.28 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
chloride channel, voltage-sensitive 4
chr8_+_67039131 0.28 ENST00000315962.4
ENST00000353317.5
tripartite motif containing 55
chr10_+_97803151 0.27 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
cyclin J
chr7_+_93535866 0.27 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr3_-_87325728 0.26 ENST00000350375.2
POU class 1 homeobox 1
chr12_-_92539614 0.26 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr7_-_117512264 0.26 ENST00000454375.1
cortactin binding protein 2
chr19_-_54618650 0.25 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr1_+_180199393 0.25 ENST00000263726.2
LIM homeobox 4
chr1_-_169703203 0.25 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
selectin E
chr1_-_151148492 0.25 ENST00000295314.4
tropomodulin 4 (muscle)
chr2_+_177015950 0.25 ENST00000306324.3
homeobox D4
chr5_+_137722255 0.25 ENST00000542866.1
lysine (K)-specific demethylase 3B
chr17_+_71228537 0.24 ENST00000577615.1
ENST00000585109.1
chromosome 17 open reading frame 80
chr2_+_36923830 0.24 ENST00000379242.3
ENST00000389975.3
vitrin
chr11_+_1295809 0.24 ENST00000598274.1
Uncharacterized protein
chr5_+_140207536 0.24 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr16_+_68119247 0.24 ENST00000575270.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr1_+_206557366 0.24 ENST00000414007.1
ENST00000419187.2
SLIT-ROBO Rho GTPase activating protein 2
chr14_+_39944025 0.24 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr6_+_34204642 0.24 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr1_+_225600404 0.23 ENST00000366845.2
AC092811.1
chr2_+_179317994 0.23 ENST00000375129.4
deafness, autosomal recessive 59
chr15_-_34331243 0.23 ENST00000306730.3
apoptosis, caspase activation inhibitor
chr9_+_136501478 0.23 ENST00000393056.2
ENST00000263611.2
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr10_+_67330096 0.23 ENST00000433152.4
ENST00000601979.1
ENST00000599409.1
ENST00000608678.1
RP11-222A11.1
chr1_+_84630645 0.22 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_136070614 0.21 ENST00000502421.1
CTB-1I21.1
chr8_+_86999516 0.21 ENST00000521564.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr12_+_2912363 0.21 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr9_+_27524283 0.20 ENST00000276943.2
interferon, kappa
chr13_-_45775162 0.20 ENST00000405872.1
potassium channel tetramerization domain containing 4
chr14_-_21567009 0.20 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
zinc finger protein 219
chr16_+_69373323 0.20 ENST00000254940.5
NIP7, nucleolar pre-rRNA processing protein
chr5_+_133562095 0.20 ENST00000602919.1
CTD-2410N18.3
chr3_-_33686743 0.19 ENST00000333778.6
ENST00000539981.1
cytoplasmic linker associated protein 2
chr15_+_51669513 0.18 ENST00000558426.1
gliomedin
chr19_-_54619006 0.18 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr3_+_111697843 0.18 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
abhydrolase domain containing 10
chrX_-_138724994 0.18 ENST00000536274.1
MCF.2 cell line derived transforming sequence
chr17_-_38911580 0.18 ENST00000312150.4
keratin 25
chr2_+_74685413 0.18 ENST00000233615.2
WW domain binding protein 1
chr3_-_186262166 0.18 ENST00000307944.5
crystallin, gamma S
chr8_-_10512569 0.17 ENST00000382483.3
retinitis pigmentosa 1-like 1
chr17_-_39623681 0.17 ENST00000225899.3
keratin 32
chr17_-_38956205 0.17 ENST00000306658.7
keratin 28
chrX_+_36254051 0.17 ENST00000378657.4
chromosome X open reading frame 30
chr5_-_66492562 0.16 ENST00000256447.4
CD180 molecule
chr11_-_57479673 0.16 ENST00000337672.2
ENST00000431606.2
mediator complex subunit 19

Network of associatons between targets according to the STRING database.

First level regulatory network of DRGX_PROP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.7 9.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.5 2.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.5 2.8 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.4 2.1 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.4 1.4 GO:0000103 sulfate assimilation(GO:0000103)
0.3 0.8 GO:0002188 translation reinitiation(GO:0002188)
0.3 0.8 GO:0045062 extrathymic T cell selection(GO:0045062)
0.3 0.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.7 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 0.9 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.2 1.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.5 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 1.3 GO:0015811 L-cystine transport(GO:0015811)
0.2 2.2 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.2 2.9 GO:0014029 neural crest formation(GO:0014029)
0.1 0.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.6 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.6 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.5 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.7 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.1 GO:0070836 caveola assembly(GO:0070836)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.3 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.4 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 1.4 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.3 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.4 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 1.1 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.4 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.0 1.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.4 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.0 GO:1901380 negative regulation of potassium ion transport(GO:0043267) negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 2.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.7 GO:0051775 response to redox state(GO:0051775)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 1.2 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.9 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.3 GO:0009615 response to virus(GO:0009615)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0043069 negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069)
0.0 0.7 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.4 GO:0007625 grooming behavior(GO:0007625)
0.0 0.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.1 GO:0005577 fibrinogen complex(GO:0005577)
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 5.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.5 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 1.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.8 GO:1990357 terminal web(GO:1990357)
0.1 1.2 GO:0060091 kinocilium(GO:0060091)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.0 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.9 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 1.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.5 1.4 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 1.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.4 1.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.3 1.3 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.3 0.9 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.3 2.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 1.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 5.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.7 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.6 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.3 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.4 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 2.2 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 9.3 GO:0051087 chaperone binding(GO:0051087)
0.0 3.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 2.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 5.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane