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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DUXA

Z-value: 1.09

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Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
DUXA
ENSG00000258873.2 double homeobox A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DUXAhg19_v2_chr19_-_57678811_57678811-0.714.7e-04Click!

Activity profile of DUXA motif

Sorted Z-values of DUXA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_150948414 4.13 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chr18_+_61554932 4.07 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr19_-_51472031 4.05 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr1_+_153003671 3.92 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr15_+_98503922 3.79 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr6_-_150346607 3.18 ENST00000367341.1
ENST00000286380.2
RAET1L
retinoic acid early transcript 1L
chr3_+_118892411 3.02 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr4_+_69313145 3.00 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr8_-_49834299 2.97 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr18_+_61445007 2.97 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_152975488 2.85 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr19_-_51471381 2.83 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr3_-_176914191 2.83 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr2_+_234600253 2.75 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr8_-_49833978 2.75 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr18_+_61445205 2.48 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_-_42801540 2.35 ENST00000372573.1
FOXJ3
forkhead box J3
chr8_-_125577940 2.26 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr11_+_32851487 2.17 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr1_-_153113927 2.14 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr11_-_119991589 2.12 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr5_+_149877334 2.12 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chrX_+_135614293 2.09 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr16_+_57220049 2.07 ENST00000562439.1
RSPRY1
ring finger and SPRY domain containing 1
chr6_+_86195088 2.06 ENST00000437581.1
NT5E
5'-nucleotidase, ecto (CD73)
chr3_+_118892362 2.00 ENST00000497685.1
ENST00000264234.3
UPK1B
uroplakin 1B
chr6_+_41604620 1.94 ENST00000432027.1
MDFI
MyoD family inhibitor
chr5_+_150404904 1.93 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr8_+_24151553 1.92 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr11_+_93754513 1.89 ENST00000315765.9
HEPHL1
hephaestin-like 1
chr11_-_96076334 1.86 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr1_+_116915270 1.73 ENST00000418797.1
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_-_22222764 1.68 ENST00000439717.2
ENST00000412328.1
HSPG2
heparan sulfate proteoglycan 2
chr2_+_169923504 1.67 ENST00000357546.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr17_+_61151306 1.67 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_+_77941685 1.66 ENST00000506731.1
SEPT11
septin 11
chr5_-_74326724 1.59 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr5_-_31532238 1.59 ENST00000507438.1
DROSHA
drosha, ribonuclease type III
chr1_-_154941350 1.58 ENST00000444179.1
ENST00000414115.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr5_-_95297534 1.57 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr15_-_44116873 1.53 ENST00000267812.3
MFAP1
microfibrillar-associated protein 1
chr4_+_76649753 1.53 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr11_+_13690249 1.49 ENST00000532701.1
FAR1
fatty acyl CoA reductase 1
chr8_+_24151620 1.49 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr6_+_116691001 1.48 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr11_+_10772534 1.46 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr8_-_29605625 1.43 ENST00000506121.3
LINC00589
long intergenic non-protein coding RNA 589
chr4_+_89514402 1.42 ENST00000426683.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr11_+_43333513 1.41 ENST00000534695.1
ENST00000455725.2
ENST00000531273.1
ENST00000420461.2
ENST00000378852.3
ENST00000534600.1
API5
apoptosis inhibitor 5
chr6_-_26199499 1.41 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chrX_+_100878112 1.38 ENST00000491568.2
ENST00000479298.1
ARMCX3
armadillo repeat containing, X-linked 3
chr20_+_22034809 1.35 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr5_-_95297678 1.35 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr4_+_148653206 1.34 ENST00000336498.3
ARHGAP10
Rho GTPase activating protein 10
chr2_+_169923577 1.33 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr17_+_66511540 1.32 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr3_-_195997410 1.32 ENST00000419333.1
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
chr1_-_220219775 1.32 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr19_-_51471362 1.30 ENST00000376853.4
ENST00000424910.2
KLK6
kallikrein-related peptidase 6
chr4_-_87028478 1.29 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr5_+_145826867 1.29 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr12_+_14572070 1.29 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr3_+_107364769 1.27 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr4_+_169552748 1.27 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr11_-_11374904 1.26 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr6_-_26199471 1.24 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr1_+_117963209 1.24 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr6_+_130339710 1.23 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr12_-_91546926 1.23 ENST00000550758.1
DCN
decorin
chr4_+_89514516 1.20 ENST00000452979.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr4_+_76649797 1.20 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr3_-_12587055 1.19 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr6_-_138820624 1.19 ENST00000343505.5
NHSL1
NHS-like 1
chr17_+_61271355 1.18 ENST00000583356.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_-_119759795 1.16 ENST00000419654.2
SEC24D
SEC24 family member D
chr7_+_18330035 1.14 ENST00000413509.2
HDAC9
histone deacetylase 9
chr6_+_30856507 1.14 ENST00000513240.1
ENST00000424544.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr10_-_33281363 1.14 ENST00000534049.1
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr21_-_16254231 1.14 ENST00000412426.1
ENST00000418954.1
AF127936.7
AF127936.7
chr15_-_42749711 1.13 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106
zinc finger protein 106
chr19_-_12833361 1.12 ENST00000592287.1
TNPO2
transportin 2
chr5_+_125758865 1.11 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr1_+_40942887 1.10 ENST00000372706.1
ZFP69
ZFP69 zinc finger protein
chr16_-_15149917 1.09 ENST00000287706.3
NTAN1
N-terminal asparagine amidase
chr12_-_49245916 1.09 ENST00000552512.1
ENST00000551468.1
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr9_+_124329336 1.09 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr10_-_29923893 1.08 ENST00000355867.4
SVIL
supervillin
chr11_+_10772847 1.07 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr16_+_24549014 1.07 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr8_+_82192501 1.06 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr17_+_79031415 1.05 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr4_-_87770416 1.05 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr12_-_118628350 1.05 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr18_-_53253323 1.05 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chrX_+_37865804 1.04 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr1_+_17575584 1.04 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr10_-_29811456 1.03 ENST00000535393.1
SVIL
supervillin
chr18_-_53253112 1.01 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr17_+_66521936 1.00 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_+_125758813 0.99 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr1_-_12908578 0.99 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr16_+_57220193 0.98 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr1_-_91487770 0.98 ENST00000337393.5
ZNF644
zinc finger protein 644
chr19_-_2090131 0.95 ENST00000591326.1
MOB3A
MOB kinase activator 3A
chr3_+_107364683 0.95 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr5_-_115872124 0.94 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr17_-_39553844 0.94 ENST00000251645.2
KRT31
keratin 31
chr1_+_78383813 0.94 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr1_+_152730499 0.93 ENST00000368773.1
KPRP
keratinocyte proline-rich protein
chr12_-_76817036 0.92 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr4_-_74088800 0.90 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr4_-_76649546 0.90 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr4_-_110651143 0.88 ENST00000243501.5
PLA2G12A
phospholipase A2, group XIIA
chr6_+_26251835 0.88 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr1_-_224624730 0.88 ENST00000445239.1
WDR26
WD repeat domain 26
chr5_+_102201687 0.87 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr21_+_30502806 0.85 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr5_-_115872142 0.85 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr18_-_74839891 0.85 ENST00000581878.1
MBP
myelin basic protein
chr2_+_160590469 0.84 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr19_-_12833164 0.84 ENST00000356861.5
TNPO2
transportin 2
chr5_+_67535647 0.83 ENST00000520675.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr6_+_35996859 0.83 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr14_+_85994943 0.82 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr6_-_111888474 0.81 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr18_-_59415987 0.81 ENST00000590199.1
ENST00000590968.1
RP11-879F14.1
RP11-879F14.1
chr1_-_91487806 0.81 ENST00000361321.5
ZNF644
zinc finger protein 644
chr3_+_107318157 0.81 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr5_+_102201722 0.81 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr6_+_150920999 0.80 ENST00000367328.1
ENST00000367326.1
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr12_-_112123524 0.79 ENST00000327551.6
BRAP
BRCA1 associated protein
chr14_-_102552659 0.79 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr11_+_121447469 0.79 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr15_+_44719996 0.78 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chrX_+_149867681 0.77 ENST00000438018.1
ENST00000436701.1
MTMR1
myotubularin related protein 1
chr12_+_32115400 0.77 ENST00000381054.3
KIAA1551
KIAA1551
chr10_+_180643 0.77 ENST00000509513.2
ENST00000397959.3
ZMYND11
zinc finger, MYND-type containing 11
chr16_-_58663720 0.75 ENST00000564557.1
ENST00000569240.1
ENST00000441024.2
ENST00000569020.1
ENST00000317147.5
CNOT1
CCR4-NOT transcription complex, subunit 1
chr13_+_76362974 0.75 ENST00000497947.2
LMO7
LIM domain 7
chr4_-_14889791 0.74 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr8_+_124864227 0.74 ENST00000522917.1
FER1L6
fer-1-like 6 (C. elegans)
chr5_+_125759140 0.71 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr1_-_153283194 0.70 ENST00000290722.1
PGLYRP3
peptidoglycan recognition protein 3
chr12_+_28299014 0.68 ENST00000538586.1
ENST00000536154.1
CCDC91
coiled-coil domain containing 91
chr6_+_45296391 0.67 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr1_-_115124257 0.67 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr1_+_92632542 0.67 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr7_+_134331550 0.67 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM
2,3-bisphosphoglycerate mutase
chr3_+_120461484 0.67 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr7_+_132937820 0.66 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr1_+_53480598 0.66 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr11_-_95522907 0.66 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr11_-_95523500 0.66 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chr5_+_140079919 0.65 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr1_-_220220000 0.64 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr19_-_57967854 0.63 ENST00000321039.3
VN1R1
vomeronasal 1 receptor 1
chr15_-_43398274 0.63 ENST00000382177.2
ENST00000290650.4
UBR1
ubiquitin protein ligase E3 component n-recognin 1
chr16_-_57219721 0.63 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
FAM192A
family with sequence similarity 192, member A
chr4_+_56719782 0.63 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1
exocyst complex component 1
chr16_+_31724552 0.63 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr5_+_81601166 0.63 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr1_+_209929494 0.62 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr6_+_42584847 0.61 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr11_-_16419067 0.61 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr11_+_118230287 0.60 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr12_+_26164645 0.59 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_-_134639042 0.58 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr14_+_55595762 0.58 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr13_+_20207782 0.57 ENST00000414242.2
ENST00000361479.5
MPHOSPH8
M-phase phosphoprotein 8
chr12_+_56522001 0.57 ENST00000267113.4
ENST00000541590.1
ESYT1
extended synaptotagmin-like protein 1
chr1_-_21377383 0.56 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr7_+_8008418 0.56 ENST00000223145.5
GLCCI1
glucocorticoid induced transcript 1
chr5_-_16742330 0.55 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chr5_+_154238149 0.55 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr7_+_30589829 0.54 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chrX_-_68385274 0.54 ENST00000374584.3
ENST00000590146.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr7_-_137686791 0.54 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr10_-_61900762 0.53 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr18_-_53253000 0.53 ENST00000566514.1
TCF4
transcription factor 4
chr5_+_140723601 0.51 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chr15_+_44719790 0.51 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr2_+_86333340 0.51 ENST00000409783.2
ENST00000409277.3
PTCD3
pentatricopeptide repeat domain 3
chr3_+_179280668 0.50 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr5_+_154237778 0.50 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr6_-_75953484 0.50 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chrX_+_100878079 0.49 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr11_+_125464758 0.48 ENST00000529886.1
STT3A
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr5_-_77590480 0.48 ENST00000519295.1
ENST00000255194.6
AP3B1
adaptor-related protein complex 3, beta 1 subunit
chr8_-_114449112 0.48 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr22_+_41697520 0.48 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr7_+_17414360 0.48 ENST00000419463.1
AC019117.1
AC019117.1
chr5_-_150537279 0.48 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6
annexin A6
chr3_+_97483366 0.46 ENST00000463745.1
ENST00000462412.1
ARL6
ADP-ribosylation factor-like 6
chr9_+_88556444 0.46 ENST00000376040.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr22_+_45725524 0.46 ENST00000405548.3
FAM118A
family with sequence similarity 118, member A
chr17_+_45728427 0.46 ENST00000540627.1
KPNB1
karyopherin (importin) beta 1
chr11_+_13690200 0.45 ENST00000354817.3
FAR1
fatty acyl CoA reductase 1
chr4_-_100212132 0.45 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chrM_+_10758 0.44 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr14_+_101293687 0.44 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.1 5.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.7 2.0 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.6 2.5 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.5 1.6 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.4 2.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.4 1.9 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.4 8.2 GO:0016540 protein autoprocessing(GO:0016540)
0.3 1.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.3 2.2 GO:0030035 microspike assembly(GO:0030035)
0.3 1.7 GO:0018032 protein amidation(GO:0018032)
0.3 1.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.3 3.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 0.8 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 1.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 0.7 GO:0051714 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.2 1.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.0 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 2.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 2.8 GO:0060613 fat pad development(GO:0060613)
0.2 1.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 0.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 0.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 1.1 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.2 2.1 GO:0006477 protein sulfation(GO:0006477)
0.2 0.5 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 0.8 GO:0043335 protein unfolding(GO:0043335)
0.2 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.7 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.2 2.0 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.9 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 2.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.8 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 1.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 2.0 GO:2000628 production of siRNA involved in RNA interference(GO:0030422) regulation of miRNA metabolic process(GO:2000628)
0.1 10.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.6 GO:0061015 snRNA import into nucleus(GO:0061015)
0.1 0.5 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 1.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.6 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.1 4.1 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.7 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.3 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 1.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.5 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.3 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 1.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.6 GO:0019236 response to pheromone(GO:0019236)
0.1 1.2 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.4 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 1.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.9 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.2 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 1.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.8 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 1.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.9 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.3 GO:0072602 interleukin-33-mediated signaling pathway(GO:0038172) interleukin-4 secretion(GO:0072602)
0.0 1.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.9 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.7 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 4.2 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 1.7 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.4 GO:0032808 lacrimal gland development(GO:0032808)
0.0 1.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.8 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 1.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.4 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 1.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 3.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.8 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.3 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.7 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.6 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 2.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.7 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 3.3 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.4 1.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.4 1.1 GO:1990032 parallel fiber(GO:1990032)
0.2 2.0 GO:0097452 GAIT complex(GO:0097452)
0.2 2.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 1.6 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 2.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 0.6 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 2.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 8.9 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.5 GO:0031417 NatC complex(GO:0031417)
0.1 2.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.2 GO:0042587 glycogen granule(GO:0042587)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.7 GO:0070552 BRISC complex(GO:0070552)
0.1 0.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 1.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.1 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 1.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.6 GO:0005682 U5 snRNP(GO:0005682)
0.0 2.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 2.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 3.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 5.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 3.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 2.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:1990904 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.6 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.2 GO:0045177 apical part of cell(GO:0045177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.3 2.0 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.3 1.9 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 1.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.3 2.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.3 1.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.7 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.3 1.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 3.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 3.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 0.7 GO:0070538 oleic acid binding(GO:0070538)
0.2 0.6 GO:0016503 pheromone receptor activity(GO:0016503)
0.2 1.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 1.2 GO:0070728 leucine binding(GO:0070728)
0.2 1.6 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 0.7 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.2 0.7 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 1.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 2.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.6 GO:0019863 IgE binding(GO:0019863)
0.1 1.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 2.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.7 GO:1990239 steroid hormone binding(GO:1990239)
0.1 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 2.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 3.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 3.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 2.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.8 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.9 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 5.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 7.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 10.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 1.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 4.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.7 PID ARF 3PATHWAY Arf1 pathway
0.1 4.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 5.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 4.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 4.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 6.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.0 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 3.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 2.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 2.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.3 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions