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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EMX1

Z-value: 0.48

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Transcription factors associated with EMX1

Gene Symbol Gene ID Gene Info
EMX1
ENSG00000135638.9 empty spiracles homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX1hg19_v2_chr2_+_73144604_73144654-0.426.2e-02Click!

Activity profile of EMX1 motif

Sorted Z-values of EMX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_151034734 2.83 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr17_-_39743139 1.76 ENST00000167586.6
KRT14
keratin 14
chr12_-_28122980 1.64 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr8_-_49833978 1.57 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr12_-_28123206 1.49 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr1_+_152881014 1.39 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr2_+_158114051 1.28 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr12_-_50616382 1.23 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr11_-_118134997 1.21 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr4_-_74486217 1.19 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr11_+_35222629 1.16 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr8_-_49834299 1.15 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr11_-_118135160 1.14 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr18_-_33702078 1.12 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr4_-_74486347 1.11 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr19_-_51522955 1.10 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr13_+_110958124 1.08 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr18_-_33709268 1.08 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr16_+_53133070 1.05 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr14_+_62164340 1.02 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr4_-_74486109 1.00 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_+_169013666 1.00 ENST00000359299.3
ANXA10
annexin A10
chr5_-_95297534 0.99 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr4_+_106631966 0.99 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr1_+_145439306 0.99 ENST00000425134.1
TXNIP
thioredoxin interacting protein
chr13_-_38172863 0.99 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr5_+_31193847 0.98 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr2_-_214016314 0.96 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr10_-_115904361 0.92 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr11_-_104905840 0.86 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr17_+_61151306 0.84 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr10_+_5454505 0.83 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr14_-_23652849 0.83 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr11_-_96076334 0.81 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr19_+_58570605 0.79 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
ZNF135
zinc finger protein 135
chr8_-_124553437 0.78 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr4_-_143226979 0.78 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr11_-_129062093 0.78 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr4_-_143227088 0.77 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_-_83824449 0.73 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_+_111717511 0.72 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chrM_-_14670 0.72 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr14_+_52164820 0.72 ENST00000554167.1
FRMD6
FERM domain containing 6
chr5_-_95297678 0.71 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr5_+_66300464 0.71 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr18_-_61329118 0.71 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr2_-_74618907 0.71 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr2_-_216003127 0.68 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_22222764 0.65 ENST00000439717.2
ENST00000412328.1
HSPG2
heparan sulfate proteoglycan 2
chr12_-_88974236 0.65 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr1_-_183538319 0.64 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr11_-_111794446 0.64 ENST00000527950.1
CRYAB
crystallin, alpha B
chr1_-_68698197 0.64 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr3_-_99594948 0.64 ENST00000471562.1
ENST00000495625.2
FILIP1L
filamin A interacting protein 1-like
chr6_-_138833630 0.64 ENST00000533765.1
NHSL1
NHS-like 1
chr10_+_111765562 0.64 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr5_+_36608422 0.63 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_71384300 0.63 ENST00000504451.1
AMTN
amelotin
chr8_-_42358742 0.63 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr14_+_61654271 0.63 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr11_+_65554493 0.61 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chrX_+_107334983 0.61 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr4_-_153601136 0.61 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr15_-_53002007 0.60 ENST00000561490.1
FAM214A
family with sequence similarity 214, member A
chr7_-_105029812 0.60 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr13_-_30881134 0.60 ENST00000380617.3
ENST00000441394.1
KATNAL1
katanin p60 subunit A-like 1
chr16_+_14280742 0.60 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr6_+_130339710 0.59 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr3_-_69129501 0.59 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr14_+_72052983 0.59 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr13_-_46626847 0.58 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr9_-_107690420 0.57 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr4_+_71384257 0.57 ENST00000339336.4
AMTN
amelotin
chr1_+_17559776 0.57 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr5_-_148929848 0.57 ENST00000504676.1
ENST00000515435.1
CSNK1A1
casein kinase 1, alpha 1
chr3_+_111718036 0.56 ENST00000455401.2
TAGLN3
transgelin 3
chr3_+_182983090 0.56 ENST00000465010.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr12_+_106751436 0.56 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr2_-_208031943 0.55 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr19_+_11071546 0.55 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr1_-_50889155 0.54 ENST00000404795.3
DMRTA2
DMRT-like family A2
chr13_-_99667960 0.54 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr3_-_99595037 0.54 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr3_+_111717600 0.54 ENST00000273368.4
TAGLN3
transgelin 3
chr11_-_128894053 0.53 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr2_+_191221240 0.53 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr14_+_85994943 0.53 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr10_-_116418053 0.53 ENST00000277895.5
ABLIM1
actin binding LIM protein 1
chr11_-_107729504 0.53 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr14_-_21737551 0.53 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr4_-_119759795 0.53 ENST00000419654.2
SEC24D
SEC24 family member D
chr5_-_24645078 0.52 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr3_-_74570291 0.52 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr20_+_12989596 0.52 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr8_-_128231299 0.52 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr4_+_159727272 0.51 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr3_-_168865522 0.50 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr5_+_66300446 0.50 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr5_-_150473127 0.50 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr12_+_6419877 0.50 ENST00000536531.1
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr18_-_21891460 0.50 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr4_+_169633310 0.49 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr8_-_101963482 0.49 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_+_107364769 0.49 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr8_-_29120604 0.49 ENST00000521515.1
KIF13B
kinesin family member 13B
chr1_+_160370344 0.49 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr13_-_41593425 0.48 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr18_-_68004529 0.48 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr1_-_152386732 0.47 ENST00000271835.3
CRNN
cornulin
chrX_+_107334895 0.47 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr11_-_107729287 0.47 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr4_-_152149033 0.47 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr3_+_156799587 0.47 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr2_+_29320571 0.46 ENST00000401605.1
ENST00000401617.2
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr20_-_46415341 0.46 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr18_+_55888767 0.46 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr5_-_16916624 0.46 ENST00000513882.1
MYO10
myosin X
chr4_+_169418255 0.46 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr8_-_42396185 0.45 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_+_64798826 0.45 ENST00000540203.1
XPOT
exportin, tRNA
chr7_-_27169801 0.45 ENST00000511914.1
HOXA4
homeobox A4
chr4_+_144312659 0.45 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr6_-_138866823 0.45 ENST00000342260.5
NHSL1
NHS-like 1
chr1_-_68698222 0.45 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr14_-_36988882 0.45 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr8_+_107460147 0.45 ENST00000442977.2
OXR1
oxidation resistance 1
chr7_-_92777606 0.44 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr1_+_236958554 0.44 ENST00000366577.5
ENST00000418145.2
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chr21_-_35899113 0.44 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr5_+_125758865 0.44 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr6_-_75994025 0.43 ENST00000518161.1
TMEM30A
transmembrane protein 30A
chr5_-_142077569 0.43 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr18_+_32173276 0.42 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr3_-_33686925 0.42 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr5_-_159846066 0.41 ENST00000519349.1
ENST00000520664.1
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr10_-_28571015 0.41 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr9_-_179018 0.41 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr13_-_30880979 0.41 ENST00000414289.1
KATNAL1
katanin p60 subunit A-like 1
chr3_+_50211240 0.41 ENST00000420831.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr5_+_137673200 0.41 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr6_+_76330355 0.41 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr16_-_66764119 0.40 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chrX_-_73051037 0.40 ENST00000445814.1
XIST
X inactive specific transcript (non-protein coding)
chr20_-_46415297 0.40 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr2_+_113816685 0.39 ENST00000393200.2
IL36RN
interleukin 36 receptor antagonist
chr12_-_48164812 0.39 ENST00000549151.1
ENST00000548919.1
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr14_-_70883708 0.39 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr7_-_83824169 0.39 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_224624730 0.38 ENST00000445239.1
WDR26
WD repeat domain 26
chr16_+_58010339 0.38 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chr3_+_121774202 0.38 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr5_+_125758813 0.38 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr2_+_171034646 0.38 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr15_+_59279851 0.38 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chr12_-_85306562 0.38 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr6_-_109702885 0.37 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr17_-_40288449 0.37 ENST00000552162.1
ENST00000550504.1
RAB5C
RAB5C, member RAS oncogene family
chr15_+_41913690 0.37 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chrX_+_7137475 0.37 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr14_-_21737610 0.37 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr12_-_112123524 0.36 ENST00000327551.6
BRAP
BRCA1 associated protein
chr3_+_182983126 0.36 ENST00000481531.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr1_-_9953295 0.36 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr20_+_33292507 0.36 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr3_-_98619999 0.36 ENST00000449482.1
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr11_-_111649074 0.36 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr6_-_111927449 0.35 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr3_+_179322481 0.35 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr4_-_25865159 0.35 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_-_116504448 0.34 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr12_+_44229846 0.34 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr12_-_85306594 0.34 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr11_-_118023490 0.34 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr19_-_14064114 0.34 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr17_-_38859996 0.34 ENST00000264651.2
KRT24
keratin 24
chr10_+_24738355 0.34 ENST00000307544.6
KIAA1217
KIAA1217
chr12_-_56693758 0.34 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
CS
citrate synthase
chr2_-_17981462 0.34 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr10_+_126630692 0.34 ENST00000359653.4
ZRANB1
zinc finger, RAN-binding domain containing 1
chr11_+_119076745 0.33 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr3_-_46000146 0.33 ENST00000438446.1
FYCO1
FYVE and coiled-coil domain containing 1
chr17_+_33914424 0.33 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr16_+_1359511 0.33 ENST00000397514.3
ENST00000397515.2
ENST00000567383.1
ENST00000403747.2
ENST00000566587.1
UBE2I
ubiquitin-conjugating enzyme E2I
chr8_-_127570603 0.33 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chrX_-_77225135 0.33 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr6_-_111927062 0.32 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr11_-_107729887 0.32 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr9_-_136933615 0.32 ENST00000371834.2
BRD3
bromodomain containing 3
chr13_-_36050819 0.32 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr12_+_32638897 0.31 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr3_-_46000064 0.31 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr3_+_111718173 0.31 ENST00000494932.1
TAGLN3
transgelin 3
chrX_+_134654540 0.31 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_+_128399965 0.31 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr20_+_12989822 0.31 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr3_-_141747950 0.31 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_44646162 0.31 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr11_-_3818688 0.30 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
NUP98
nucleoporin 98kDa
chrX_+_46696372 0.30 ENST00000218340.3
RP2
retinitis pigmentosa 2 (X-linked recessive)
chrX_-_77150911 0.30 ENST00000373336.3
MAGT1
magnesium transporter 1

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.4 1.2 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.3 1.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.3 1.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 1.4 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 1.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.5 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 0.6 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.2 0.9 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 1.0 GO:0061030 neural fold elevation formation(GO:0021502) elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.2 0.6 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 0.7 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.7 GO:0035627 ceramide transport(GO:0035627)
0.2 1.0 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.2 0.5 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 1.1 GO:0051697 protein delipidation(GO:0051697)
0.2 0.6 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.6 GO:0032489 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.6 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.6 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 2.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 1.0 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.5 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 2.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 3.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.3 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.3 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.7 GO:0003383 apical constriction(GO:0003383)
0.1 0.4 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.2 GO:1904172 septin ring assembly(GO:0000921) septin ring organization(GO:0031106) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.1 0.7 GO:0015820 leucine transport(GO:0015820)
0.1 0.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.4 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.3 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 1.1 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.4 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 0.7 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.6 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.6 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.4 GO:0006706 steroid catabolic process(GO:0006706)
0.1 1.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.8 GO:0051451 myoblast migration(GO:0051451)
0.0 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.8 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 1.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.7 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.9 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.4 GO:0030522 intracellular receptor signaling pathway(GO:0030522)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.9 GO:0015695 organic cation transport(GO:0015695)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 2.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 1.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 2.5 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.6 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0043584 nose development(GO:0043584)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.6 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.5 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 0.1 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.9 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.0 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.5 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.4 GO:0051642 centrosome localization(GO:0051642)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0061458 reproductive system development(GO:0061458)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.9 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 1.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 1.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.0 GO:0005869 dynactin complex(GO:0005869)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 2.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.1 GO:0036457 keratohyalin granule(GO:0036457)
0.0 1.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 1.8 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 1.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 1.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 0.7 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 1.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 0.9 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 0.6 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 1.2 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.7 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.5 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.5 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.5 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 2.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 3.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.3 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.3 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 1.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0016887 ATPase activity(GO:0016887)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 4.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 1.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)