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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EMX2

Z-value: 0.99

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Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
EMX2
ENSG00000170370.10 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX2hg19_v2_chr10_+_119301928_1193019550.426.3e-02Click!

Activity profile of EMX2 motif

Sorted Z-values of EMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39093672 3.34 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr11_-_327537 3.16 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr11_+_5710919 2.99 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr12_-_123187890 2.49 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr19_-_43969796 2.31 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr18_+_29027696 2.24 ENST00000257189.4
DSG3
desmoglein 3
chr1_+_159931002 2.20 ENST00000443364.1
ENST00000423943.1
RP11-48O20.4
long intergenic non-protein coding RNA 1133
chr12_-_123201337 2.20 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr11_-_104905840 2.14 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr12_-_10007448 1.95 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr1_+_79115503 1.87 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr1_+_152956549 1.82 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr17_+_1674982 1.78 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr11_+_12308447 1.69 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr4_+_71384300 1.64 ENST00000504451.1
AMTN
amelotin
chr11_-_18258342 1.59 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr15_-_41166414 1.57 ENST00000220507.4
RHOV
ras homolog family member V
chr11_-_104916034 1.45 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr7_+_90338712 1.39 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr15_+_101417919 1.36 ENST00000561338.1
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr1_+_87012922 1.35 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr22_+_50981079 1.33 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr11_-_104972158 1.30 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr18_-_61311485 1.22 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr14_-_69261310 1.21 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr19_+_49199209 1.21 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr8_+_24151553 1.19 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr4_+_71384257 1.16 ENST00000339336.4
AMTN
amelotin
chr6_-_138833630 1.13 ENST00000533765.1
NHSL1
NHS-like 1
chr8_-_133687813 1.10 ENST00000250173.1
ENST00000519595.1
LRRC6
leucine rich repeat containing 6
chr1_+_87012753 1.08 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr19_-_36822551 1.05 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr12_-_22063787 1.03 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_160709055 1.02 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr16_+_22524844 1.02 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr5_-_160365601 1.00 ENST00000518580.1
ENST00000518301.1
RP11-109J4.1
RP11-109J4.1
chr10_-_90611566 1.00 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr21_-_43735628 0.96 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr3_-_185538849 0.96 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr15_-_99057551 0.95 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr4_-_89205705 0.95 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr20_-_45530365 0.95 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr16_-_30102547 0.95 ENST00000279386.2
TBX6
T-box 6
chr12_+_76653611 0.93 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr11_-_46113756 0.92 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr16_-_28634874 0.91 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr18_-_68004529 0.91 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr1_+_174844645 0.90 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_196911002 0.89 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr4_-_187517928 0.89 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr4_-_89205879 0.87 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr1_+_17516275 0.87 ENST00000412427.1
RP11-380J14.1
RP11-380J14.1
chrM_+_10758 0.84 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr1_+_104104379 0.83 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr2_-_85625857 0.83 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr3_+_121774202 0.83 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr15_+_75970672 0.82 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr8_-_133687778 0.81 ENST00000518642.1
LRRC6
leucine rich repeat containing 6
chr12_+_76653682 0.81 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr8_-_57123815 0.79 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr7_+_90338547 0.79 ENST00000446790.1
CDK14
cyclin-dependent kinase 14
chr5_-_137475071 0.77 ENST00000265191.2
NME5
NME/NM23 family member 5
chr4_-_100140331 0.75 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr4_+_56212505 0.75 ENST00000505210.1
SRD5A3
steroid 5 alpha-reductase 3
chr1_+_160709076 0.74 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr4_-_100356291 0.73 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_125773085 0.72 ENST00000227474.3
ENST00000534158.1
ENST00000529801.1
PUS3
pseudouridylate synthase 3
chr11_-_128894053 0.72 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr3_-_12587055 0.71 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr6_+_26251835 0.70 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr12_+_10366223 0.69 ENST00000545290.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr6_-_134639180 0.68 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr4_+_80584903 0.65 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr2_-_207082748 0.65 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr5_+_81575281 0.65 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr16_-_21436459 0.65 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr12_+_60083118 0.65 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr3_-_186288097 0.65 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr18_+_61637159 0.64 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr10_+_91092241 0.64 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr4_+_56212270 0.63 ENST00000264228.4
SRD5A3
steroid 5 alpha-reductase 3
chr7_-_17598506 0.62 ENST00000451792.1
AC017060.1
AC017060.1
chr2_+_105050794 0.62 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr2_+_32502952 0.61 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr17_-_34757039 0.60 ENST00000455054.2
ENST00000308078.7
TBC1D3H
TBC1D3C
TBC1 domain family, member 3H
TBC1 domain family, member 3C
chr17_+_42422662 0.60 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chr17_+_42422637 0.60 ENST00000053867.3
ENST00000588143.1
GRN
granulin
chr16_-_29415350 0.59 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr11_-_26593677 0.58 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr6_+_63921399 0.57 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr18_+_21693306 0.57 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr8_-_71157595 0.56 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chrX_+_47444613 0.56 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr17_-_34503867 0.55 ENST00000589443.1
ENST00000454519.3
ENST00000586369.1
TBC1D3B
TBC1 domain family, member 3B
chr12_+_10365404 0.55 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr15_+_84115868 0.54 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr11_-_26593779 0.54 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr14_+_52164820 0.53 ENST00000554167.1
FRMD6
FERM domain containing 6
chr1_+_244998918 0.53 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr9_+_71986182 0.52 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr20_-_48732472 0.51 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr3_+_38080691 0.51 ENST00000308059.6
ENST00000346219.3
ENST00000452631.2
DLEC1
deleted in lung and esophageal cancer 1
chrX_-_9734004 0.51 ENST00000467482.1
ENST00000380929.2
GPR143
G protein-coupled receptor 143
chr4_-_68995571 0.51 ENST00000356291.2
TMPRSS11F
transmembrane protease, serine 11F
chr16_-_21868978 0.49 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4
nuclear pore complex interacting protein family, member B4
chr5_-_111754948 0.49 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr6_-_26197478 0.47 ENST00000356476.2
HIST1H3D
histone cluster 1, H3d
chr1_+_234765057 0.47 ENST00000429269.1
LINC00184
long intergenic non-protein coding RNA 184
chr1_+_117544366 0.46 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr13_-_107214291 0.46 ENST00000375926.1
ARGLU1
arginine and glutamate rich 1
chr17_+_66521936 0.45 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr3_-_48956818 0.45 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr3_-_197025447 0.45 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
DLG1
discs, large homolog 1 (Drosophila)
chrX_+_78003204 0.44 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr5_+_36608280 0.44 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr20_+_30697298 0.44 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr8_+_39770803 0.43 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr13_-_30683005 0.42 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chr16_-_74330612 0.42 ENST00000569389.1
ENST00000562888.1
AC009120.4
AC009120.4
chrX_+_55744228 0.41 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chrX_-_9734038 0.41 ENST00000431126.1
GPR143
G protein-coupled receptor 143
chr6_-_112081113 0.41 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr11_-_26593649 0.41 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr2_-_207082624 0.41 ENST00000458440.1
ENST00000437420.1
GPR1
G protein-coupled receptor 1
chr14_+_85994943 0.41 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr8_-_6115044 0.40 ENST00000519555.1
RP11-124B13.1
RP11-124B13.1
chr7_+_107224364 0.40 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr8_-_87242589 0.39 ENST00000419776.2
ENST00000297524.3
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chr9_+_71944241 0.39 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr1_-_139379 0.39 ENST00000423372.3
AL627309.1
Uncharacterized protein
chr3_+_113616317 0.39 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr16_+_11038345 0.39 ENST00000409790.1
CLEC16A
C-type lectin domain family 16, member A
chr2_+_228736335 0.39 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr10_+_13652047 0.38 ENST00000601460.1
RP11-295P9.3
Uncharacterized protein
chr18_-_5419797 0.38 ENST00000542146.1
ENST00000427684.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr17_+_42422629 0.38 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
GRN
granulin
chrX_+_55744166 0.38 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr16_+_82068873 0.37 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_86848760 0.37 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr14_+_51338816 0.37 ENST00000353130.1
ENST00000337334.2
ENST00000395752.1
ABHD12B
abhydrolase domain containing 12B
chr4_-_186570679 0.37 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr14_+_23709555 0.36 ENST00000430154.2
C14orf164
chromosome 14 open reading frame 164
chr8_+_30244580 0.35 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr21_-_43735446 0.34 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr12_-_51418549 0.34 ENST00000548150.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr1_+_78383813 0.33 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr14_+_39644387 0.33 ENST00000553331.1
ENST00000216832.4
PNN
pinin, desmosome associated protein
chr1_+_81771806 0.33 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr1_-_92952433 0.33 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr15_-_34635314 0.33 ENST00000557912.1
ENST00000328848.4
NOP10
NOP10 ribonucleoprotein
chr8_+_104892639 0.33 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr15_+_63188009 0.32 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr6_+_153552455 0.32 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr8_+_107593198 0.32 ENST00000517686.1
OXR1
oxidation resistance 1
chr10_+_15074190 0.32 ENST00000428897.1
ENST00000413672.1
OLAH
oleoyl-ACP hydrolase
chr5_-_114938090 0.31 ENST00000427199.2
TICAM2
toll-like receptor adaptor molecule 2
chr18_+_32290218 0.31 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr6_-_110501200 0.31 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WASF1
WAS protein family, member 1
chr19_+_12203100 0.30 ENST00000596883.1
ZNF788
zinc finger family member 788
chr4_+_74702214 0.30 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr2_+_28718921 0.30 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1
phospholipase B1
chr21_-_42219065 0.30 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr1_+_171154347 0.30 ENST00000209929.7
ENST00000441535.1
FMO2
flavin containing monooxygenase 2 (non-functional)
chr7_+_138915102 0.30 ENST00000486663.1
UBN2
ubinuclein 2
chrX_-_72347916 0.29 ENST00000373518.1
NAP1L6
nucleosome assembly protein 1-like 6
chr3_-_141719195 0.29 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr9_-_21368075 0.29 ENST00000449498.1
IFNA13
interferon, alpha 13
chr13_-_108867101 0.29 ENST00000356922.4
LIG4
ligase IV, DNA, ATP-dependent
chr10_-_115904361 0.29 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr21_-_30047095 0.29 ENST00000452028.1
ENST00000433310.2
AF131217.1
AF131217.1
chr14_+_103851712 0.29 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr4_-_109541539 0.28 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr17_+_67590125 0.28 ENST00000591334.1
AC003051.1
AC003051.1
chr5_+_42756903 0.28 ENST00000361970.5
ENST00000388827.4
CCDC152
coiled-coil domain containing 152
chr8_+_62747349 0.28 ENST00000517953.1
ENST00000520097.1
ENST00000519766.1
RP11-705O24.1
RP11-705O24.1
chrX_+_105412290 0.28 ENST00000357175.2
ENST00000337685.2
MUM1L1
melanoma associated antigen (mutated) 1-like 1
chr18_-_33702078 0.28 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr1_+_36549676 0.28 ENST00000207457.3
TEKT2
tektin 2 (testicular)
chr2_+_196313239 0.27 ENST00000413290.1
AC064834.1
AC064834.1
chr19_+_58144529 0.27 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211
zinc finger protein 211
chr20_+_57414743 0.27 ENST00000313949.7
GNAS
GNAS complex locus
chr11_-_107729887 0.26 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr4_-_185275104 0.26 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr17_+_67759813 0.26 ENST00000587241.1
AC003051.1
AC003051.1
chr4_-_186877806 0.26 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr4_-_85654615 0.26 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr1_+_149754227 0.26 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr18_+_6729725 0.26 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr8_+_12803176 0.26 ENST00000524591.2
KIAA1456
KIAA1456
chr4_-_68829226 0.25 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr13_-_46742630 0.25 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_120935894 0.25 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr18_+_29769978 0.25 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr12_+_80603233 0.25 ENST00000547103.1
ENST00000458043.2
OTOGL
otogelin-like
chr13_+_20268547 0.25 ENST00000601204.1
AL354808.2
AL354808.2
chr4_+_74347400 0.25 ENST00000226355.3
AFM
afamin
chr7_-_101272576 0.25 ENST00000223167.4
MYL10
myosin, light chain 10, regulatory
chr11_+_27076764 0.25 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_-_111093167 0.25 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr12_-_74686314 0.24 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.9 3.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 1.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 2.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 1.4 GO:0060166 olfactory pit development(GO:0060166)
0.3 0.8 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 1.4 GO:0016095 polyprenol catabolic process(GO:0016095)
0.2 1.2 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2 1.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.2 0.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 0.9 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.2 1.5 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 1.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 0.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 1.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 2.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 4.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.4 GO:0036269 swimming behavior(GO:0036269)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.8 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.3 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 0.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 1.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.3 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 1.1 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 1.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.8 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 7.5 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.8 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.4 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 2.9 GO:0070206 protein trimerization(GO:0070206)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.2 GO:0051180 vitamin transport(GO:0051180)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.4 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 2.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 1.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.2 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 1.6 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0070458 establishment of blood-nerve barrier(GO:0008065) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.6 GO:0006334 nucleosome assembly(GO:0006334) chromatin assembly(GO:0031497) nucleosome organization(GO:0034728)
0.0 2.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.3 GO:0042832 carbohydrate mediated signaling(GO:0009756) defense response to protozoan(GO:0042832)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0060025 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.4 2.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.5 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 1.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.8 GO:0043203 axon hillock(GO:0043203)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 2.8 GO:0005605 basal lamina(GO:0005605)
0.1 0.3 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 2.7 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.3 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005903 brush border(GO:0005903)
0.0 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 3.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 3.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0098797 plasma membrane protein complex(GO:0098797)
0.0 3.5 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.5 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.3 0.9 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.3 1.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 0.8 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 2.7 GO:0089720 caspase binding(GO:0089720)
0.2 0.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 0.6 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.2 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.9 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.6 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 2.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 2.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.2 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.3 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1 0.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.6 GO:0019864 IgG binding(GO:0019864)
0.1 0.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.3 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 1.1 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 2.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.4 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.6 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 3.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones