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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EN1_ESX1_GBX1

Z-value: 0.67

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Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol Gene ID Gene Info
EN1
ENSG00000163064.6 engrailed homeobox 1
ESX1
ENSG00000123576.5 ESX homeobox 1
GBX1
ENSG00000164900.4 gastrulation brain homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GBX1hg19_v2_chr7_-_150864635_1508647850.578.5e-03Click!
EN1hg19_v2_chr2_-_119605253_1196052640.502.6e-02Click!
ESX1hg19_v2_chrX_-_103499602_103499617-0.223.6e-01Click!

Activity profile of EN1_ESX1_GBX1 motif

Sorted Z-values of EN1_ESX1_GBX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_64225508 3.53 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_-_27998689 2.49 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6
interferon, alpha-inducible protein 6
chr7_-_77427676 2.38 ENST00000257663.3
TMEM60
transmembrane protein 60
chr19_+_45973120 2.12 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr10_+_94451574 2.10 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr12_+_20963632 2.10 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr7_-_73038867 2.04 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL
MLX interacting protein-like
chr6_-_127780510 1.99 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr7_-_73038822 1.98 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL
MLX interacting protein-like
chr11_-_31531121 1.92 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_+_20963647 1.88 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr7_+_100136811 1.87 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr4_-_105416039 1.82 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr17_+_59489112 1.74 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr16_-_29910853 1.70 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr17_-_39341594 1.67 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr9_-_75653627 1.57 ENST00000446946.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr15_+_76629064 1.55 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr8_-_1922789 1.53 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr11_-_117747327 1.52 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr14_-_37051798 1.48 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr12_+_7014064 1.46 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr12_+_52695617 1.33 ENST00000293525.5
KRT86
keratin 86
chr14_+_74034310 1.32 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr10_+_5005598 1.30 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr17_-_43045439 1.28 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr19_+_34287751 1.26 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr17_+_43238438 1.25 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr7_-_33102338 1.24 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr20_+_3776371 1.24 ENST00000245960.5
CDC25B
cell division cycle 25B
chr2_-_188419078 1.23 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_+_7013897 1.21 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr11_-_124981475 1.20 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chr1_+_153746683 1.18 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr7_-_33102399 1.17 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr5_+_174151536 1.14 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chrX_-_100129128 1.13 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr14_-_95236551 1.12 ENST00000238558.3
GSC
goosecoid homeobox
chr10_+_35484793 1.11 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr6_-_31107127 1.07 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr17_-_46716647 1.07 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr3_-_120400960 1.06 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr17_-_46690839 1.04 ENST00000498634.2
HOXB8
homeobox B8
chr3_+_149191723 1.04 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr19_+_39421556 1.03 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr10_-_5046042 1.02 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr17_-_19015945 1.01 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chr19_+_50016610 1.00 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr17_+_19091325 0.99 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr4_+_105828537 0.99 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr17_+_42634844 0.99 ENST00000315323.3
FZD2
frizzled family receptor 2
chrX_-_106243451 0.99 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr1_-_201140673 0.94 ENST00000367333.2
TMEM9
transmembrane protein 9
chr1_+_196788887 0.94 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr19_-_59084647 0.90 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr7_-_99716952 0.88 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr13_+_78315295 0.88 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr3_+_173116225 0.88 ENST00000457714.1
NLGN1
neuroligin 1
chr6_-_32908792 0.87 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr15_+_80351910 0.86 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chrX_-_100129320 0.86 ENST00000372966.3
NOX1
NADPH oxidase 1
chr6_+_127898312 0.86 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr6_-_116833500 0.85 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr1_+_153747746 0.83 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr15_-_64673630 0.83 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr6_-_26032288 0.83 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr7_-_99717463 0.82 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr22_+_46476192 0.82 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr15_+_63188009 0.80 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr19_+_50016411 0.79 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr20_-_50419055 0.78 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr9_-_116840728 0.78 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr7_-_99716914 0.77 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr15_-_55562582 0.77 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr22_+_18632666 0.76 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr13_-_67802549 0.76 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr19_+_48949030 0.75 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr19_-_39421377 0.75 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
SARS2
seryl-tRNA synthetase 2, mitochondrial
chr3_-_178984759 0.74 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chrX_-_106243294 0.73 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr14_-_23426337 0.71 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4
HAUS augmin-like complex, subunit 4
chr1_-_242612779 0.71 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr16_-_2264779 0.71 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr8_+_22424551 0.70 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr19_+_4153598 0.70 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr9_+_139780942 0.70 ENST00000247668.2
ENST00000359662.3
TRAF2
TNF receptor-associated factor 2
chr12_+_16500037 0.70 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr15_-_64673665 0.69 ENST00000300035.4
KIAA0101
KIAA0101
chr17_+_62223320 0.69 ENST00000580828.1
ENST00000582965.1
SNORA76
small nucleolar RNA, H/ACA box 76
chr19_-_41870026 0.68 ENST00000243578.3
B9D2
B9 protein domain 2
chr17_-_38928414 0.68 ENST00000335552.4
KRT26
keratin 26
chr18_-_71959159 0.68 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr14_-_23426322 0.67 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr11_-_121986923 0.67 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr1_-_190446759 0.66 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr9_-_75488984 0.65 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chr2_-_224467002 0.65 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr16_+_57844549 0.65 ENST00000564282.1
CTD-2600O9.1
uncharacterized protein LOC388282
chr17_+_42786051 0.65 ENST00000315005.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr14_-_23426270 0.64 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4
HAUS augmin-like complex, subunit 4
chr1_-_242612726 0.64 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr7_+_100860949 0.63 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr11_-_117747434 0.63 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr4_+_105828492 0.63 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr20_-_50418947 0.62 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr20_+_43538756 0.62 ENST00000537323.1
ENST00000217073.2
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr11_-_117747607 0.62 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr4_+_66536248 0.62 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr14_-_104181771 0.61 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr14_-_54423529 0.61 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chrX_-_110655306 0.61 ENST00000371993.2
DCX
doublecortin
chr12_+_16500571 0.60 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr7_-_14029515 0.60 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr2_-_216946500 0.60 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr19_+_49990811 0.59 ENST00000391857.4
ENST00000467825.2
RPL13A
ribosomal protein L13a
chrX_-_18690210 0.59 ENST00000379984.3
RS1
retinoschisin 1
chr17_-_38911580 0.58 ENST00000312150.4
KRT25
keratin 25
chrX_+_129473916 0.58 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr8_-_40755333 0.58 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr4_-_8873531 0.57 ENST00000400677.3
HMX1
H6 family homeobox 1
chr6_-_32908765 0.57 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr19_+_4007644 0.57 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr17_+_79650962 0.57 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr2_+_234826016 0.56 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr13_-_28545276 0.56 ENST00000381020.7
CDX2
caudal type homeobox 2
chr8_-_19614810 0.56 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr7_+_138145076 0.56 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr2_-_157189180 0.55 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_+_8666126 0.55 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr15_+_58702742 0.55 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr17_+_42785976 0.54 ENST00000393547.2
ENST00000398338.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr4_+_150999418 0.54 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr11_+_101918153 0.53 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr17_+_42264556 0.52 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr7_+_99717230 0.52 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr11_+_67250490 0.52 ENST00000528641.2
ENST00000279146.3
AIP
aryl hydrocarbon receptor interacting protein
chr3_-_98235962 0.52 ENST00000513873.1
CLDND1
claudin domain containing 1
chr1_+_207277590 0.52 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr12_-_10978957 0.51 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr1_+_186265399 0.51 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr13_+_78315348 0.51 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr7_-_72971934 0.51 ENST00000411832.1
BCL7B
B-cell CLL/lymphoma 7B
chr9_-_136933134 0.51 ENST00000303407.7
BRD3
bromodomain containing 3
chr17_-_79650818 0.50 ENST00000397498.4
ARL16
ADP-ribosylation factor-like 16
chr8_+_119294456 0.50 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr20_-_50418972 0.50 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr4_-_138453606 0.50 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr14_-_23426231 0.50 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chr2_+_152214098 0.50 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr9_-_131486367 0.50 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr2_-_61697862 0.49 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr12_-_10605929 0.49 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr10_-_101825151 0.49 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr12_+_52056548 0.49 ENST00000545061.1
ENST00000355133.3
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr5_+_142149955 0.49 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr15_-_37393406 0.49 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chrX_+_591524 0.48 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr16_+_103816 0.48 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr19_+_18699535 0.48 ENST00000358607.6
C19orf60
chromosome 19 open reading frame 60
chr22_+_29138013 0.48 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr2_-_176046391 0.48 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr17_-_73937116 0.47 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
FBF1
Fas (TNFRSF6) binding factor 1
chrX_+_135730297 0.47 ENST00000370629.2
CD40LG
CD40 ligand
chr19_-_56110859 0.47 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr12_+_14927270 0.47 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr9_+_34652164 0.47 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr20_+_42544782 0.46 ENST00000423191.2
ENST00000372999.1
TOX2
TOX high mobility group box family member 2
chr12_+_104680659 0.46 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr17_-_38821373 0.46 ENST00000394052.3
KRT222
keratin 222
chr6_-_89927151 0.46 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr9_-_3469181 0.46 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr2_+_143635067 0.45 ENST00000264170.4
KYNU
kynureninase
chr8_+_32579271 0.45 ENST00000518084.1
NRG1
neuregulin 1
chr12_-_10022735 0.45 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr12_+_26348246 0.45 ENST00000422622.2
SSPN
sarcospan
chr15_+_62853562 0.44 ENST00000561311.1
TLN2
talin 2
chr3_-_178103144 0.44 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chrX_-_13835147 0.44 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr12_+_113587558 0.44 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr2_-_145277569 0.44 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chrX_+_72783026 0.44 ENST00000373504.6
ENST00000373502.5
CHIC1
cysteine-rich hydrophobic domain 1
chr2_-_224467093 0.44 ENST00000305409.2
SCG2
secretogranin II
chr11_-_117748138 0.44 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr22_-_18923655 0.43 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
PRODH
proline dehydrogenase (oxidase) 1
chr12_-_15815626 0.43 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr4_+_71019903 0.43 ENST00000344526.5
C4orf40
chromosome 4 open reading frame 40
chr8_+_92261516 0.43 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr3_+_115342349 0.42 ENST00000393780.3
GAP43
growth associated protein 43
chr18_-_44181442 0.42 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr2_-_227050079 0.42 ENST00000423838.1
AC068138.1
AC068138.1
chr17_-_74733404 0.42 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chr15_-_72565340 0.42 ENST00000568360.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr12_-_6233828 0.42 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr19_-_54618650 0.41 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr14_+_101359265 0.41 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr6_+_52535878 0.41 ENST00000211314.4
TMEM14A
transmembrane protein 14A
chr5_+_142286887 0.41 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr19_+_36605850 0.41 ENST00000221855.3
TBCB
tubulin folding cofactor B
chr14_+_96000930 0.41 ENST00000331334.4
GLRX5
glutaredoxin 5
chr1_+_226013047 0.41 ENST00000366837.4
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.6 1.8 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.6 1.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.6 1.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.5 2.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.5 1.4 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.4 1.3 GO:0099558 maintenance of synapse structure(GO:0099558)
0.4 1.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.3 4.0 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.3 3.5 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.3 0.9 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3 2.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3 1.6 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 1.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 0.7 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.2 0.5 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.2 2.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.2 1.9 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 0.6 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.2 0.6 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 0.7 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.2 1.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.7 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.2 0.5 GO:0030070 insulin processing(GO:0030070)
0.1 1.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.4 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 2.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.6 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.4 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 1.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 2.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.0 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.7 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.5 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 4.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.2 GO:0050787 detoxification of mercury ion(GO:0050787)
0.1 0.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.2 GO:0007144 female meiosis I(GO:0007144)
0.1 0.3 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.3 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.6 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.6 GO:0050955 thermoception(GO:0050955)
0.1 1.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.3 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 1.0 GO:0060022 hard palate development(GO:0060022)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.7 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.3 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 2.1 GO:0051412 response to corticosterone(GO:0051412)
0.1 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.5 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.9 GO:0014029 neural crest formation(GO:0014029)
0.1 0.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.2 GO:0060922 cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.4 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.4 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 1.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.3 GO:0072164 ureteric bud development(GO:0001657) mesonephros development(GO:0001823) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 0.3 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.3 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.5 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 1.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.4 GO:0008652 cellular amino acid biosynthetic process(GO:0008652)
0.0 1.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 1.1 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.7 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.8 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.2 GO:1902952 regulation of postsynaptic density protein 95 clustering(GO:1902897) positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.3 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.1 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 3.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.1 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.4 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 2.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.5 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.6 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.7 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 1.1 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 1.7 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.0 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 2.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:2000974 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0035067 negative regulation of histone acetylation(GO:0035067)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 1.3 GO:0044301 climbing fiber(GO:0044301)
0.2 0.7 GO:0097057 TRAF2-GSTP1 complex(GO:0097057) AIP1-IRE1 complex(GO:1990597)
0.2 3.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 2.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 3.0 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 2.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.7 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.3 GO:0097196 Shu complex(GO:0097196)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 1.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.1 GO:0031045 dense core granule(GO:0031045)
0.0 3.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.7 GO:0097346 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 2.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.6 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 2.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.5 1.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 1.8 GO:0019770 IgG receptor activity(GO:0019770)
0.3 2.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 2.3 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.3 0.8 GO:0019862 IgA binding(GO:0019862)
0.2 0.7 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 0.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 0.6 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.2 1.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 3.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 4.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.4 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 1.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.5 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 2.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 1.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 2.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.3 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.3 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.4 GO:0043295 glutathione binding(GO:0043295)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 0.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 6.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.0 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.0 GO:0016826 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020) photoreceptor activity(GO:0009881)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 1.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0015288 porin activity(GO:0015288)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 2.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 2.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 3.4 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)