Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for EN2_GBX2_LBX2

Z-value: 0.63

Motif logo

logo of logo of logo of

Transcription factors associated with EN2_GBX2_LBX2

Gene Symbol Gene ID Gene Info
EN2
ENSG00000164778.4 engrailed homeobox 2
GBX2
ENSG00000168505.6 gastrulation brain homeobox 2
LBX2
ENSG00000179528.11 ladybird homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GBX2hg19_v2_chr2_-_237076992_237077012-0.877.3e-07Click!
LBX2hg19_v2_chr2_-_74730430_74730451-0.852.2e-06Click!
EN2hg19_v2_chr7_+_155250824_155250824-0.723.5e-04Click!

Activity profile of EN2_GBX2_LBX2 motif

Sorted Z-values of EN2_GBX2_LBX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_89746173 2.07 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr3_-_195538760 1.74 ENST00000475231.1
MUC4
mucin 4, cell surface associated
chr5_+_31193847 1.52 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr5_-_95297678 1.52 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr6_+_130339710 1.47 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr12_-_28122980 1.46 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr5_-_95297534 1.41 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr8_+_38831683 1.34 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr19_-_51522955 1.34 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr12_-_28123206 1.33 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr6_-_111927449 1.32 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr5_+_66300464 1.29 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_+_111717511 1.14 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr5_+_66300446 1.13 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_-_195538728 1.11 ENST00000349607.4
ENST00000346145.4
MUC4
mucin 4, cell surface associated
chr5_+_125758865 1.09 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr18_+_32173276 1.04 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr6_-_111927062 1.04 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chrM_+_12331 1.02 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr5_+_125758813 1.01 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr2_+_171034646 1.01 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr8_-_128231299 1.00 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr12_-_89746264 0.98 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr4_+_169013666 0.96 ENST00000359299.3
ANXA10
annexin A10
chr3_+_111718036 0.96 ENST00000455401.2
TAGLN3
transgelin 3
chr19_-_14064114 0.94 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr6_-_26199471 0.87 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr3_+_111717600 0.85 ENST00000273368.4
TAGLN3
transgelin 3
chr18_-_33709268 0.85 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr6_-_26199499 0.85 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr9_+_1050331 0.75 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
DMRT2
doublesex and mab-3 related transcription factor 2
chr2_+_158114051 0.73 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_-_152386732 0.72 ENST00000271835.3
CRNN
cornulin
chr22_+_41777927 0.71 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr16_+_53133070 0.71 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr6_-_39693111 0.70 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6
kinesin family member 6
chr5_+_125759140 0.68 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chrX_+_134654540 0.68 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr20_-_50722183 0.65 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr18_+_55888767 0.65 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr12_-_52828147 0.65 ENST00000252245.5
KRT75
keratin 75
chr14_+_32798462 0.61 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr13_-_41593425 0.61 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr14_+_104182105 0.61 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr4_-_36245561 0.59 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_52090461 0.59 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr5_-_115890554 0.56 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_+_17997763 0.55 ENST00000281047.3
MSGN1
mesogenin 1
chr14_+_104182061 0.54 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr3_+_111718173 0.53 ENST00000494932.1
TAGLN3
transgelin 3
chr17_-_76732928 0.51 ENST00000589768.1
CYTH1
cytohesin 1
chr8_+_105235572 0.49 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr19_-_14640005 0.47 ENST00000596853.1
ENST00000596075.1
ENST00000595992.1
ENST00000396969.4
ENST00000601533.1
ENST00000598692.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_-_32157947 0.43 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr1_+_145507587 0.42 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr5_+_145826867 0.41 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr1_+_118472343 0.41 ENST00000369441.3
ENST00000349139.5
WDR3
WD repeat domain 3
chr9_+_2159850 0.40 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_-_74486217 0.40 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_-_118472171 0.38 ENST00000369442.3
GDAP2
ganglioside induced differentiation associated protein 2
chr1_-_118472216 0.38 ENST00000369443.5
GDAP2
ganglioside induced differentiation associated protein 2
chr14_+_72052983 0.38 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr4_-_143226979 0.37 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_143227088 0.36 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr6_-_167040693 0.36 ENST00000366863.2
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr4_-_39979576 0.36 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr7_+_74072288 0.35 ENST00000443166.1
GTF2I
general transcription factor IIi
chr6_-_32145861 0.35 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr16_+_9185450 0.34 ENST00000327827.7
C16orf72
chromosome 16 open reading frame 72
chr1_-_23670752 0.33 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr4_+_144354644 0.33 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr7_-_27169801 0.33 ENST00000511914.1
HOXA4
homeobox A4
chr4_-_74486347 0.33 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr11_-_118023490 0.32 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr1_-_68698197 0.32 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr1_-_68698222 0.32 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr1_+_160370344 0.31 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr4_-_57547870 0.31 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr17_+_18086392 0.31 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr5_+_53751445 0.31 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr1_-_23670813 0.30 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr4_-_74486109 0.28 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_89205705 0.28 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr6_-_167040731 0.28 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr18_-_33702078 0.28 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr6_-_99873145 0.28 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr19_-_6737241 0.28 ENST00000430424.4
ENST00000597298.1
GPR108
G protein-coupled receptor 108
chr13_-_36788718 0.27 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr3_-_119813264 0.27 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr3_+_156799587 0.27 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr3_-_112360116 0.27 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr1_-_23670817 0.27 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr1_-_17766198 0.25 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr14_-_73360796 0.25 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr6_-_138866823 0.24 ENST00000342260.5
NHSL1
NHS-like 1
chr4_-_89205879 0.24 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chrM_+_7586 0.24 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr15_-_55562451 0.24 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr19_-_6737576 0.23 ENST00000601716.1
ENST00000264080.7
GPR108
G protein-coupled receptor 108
chr3_+_133292759 0.23 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr11_+_57435441 0.23 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr19_-_47137942 0.22 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr4_-_54232144 0.21 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
SCFD2
sec1 family domain containing 2
chr4_+_71587669 0.20 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr11_+_57435219 0.20 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr6_-_18264406 0.20 ENST00000515742.1
DEK
DEK oncogene
chr19_+_14640372 0.19 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
TECR
trans-2,3-enoyl-CoA reductase
chr19_-_7968427 0.19 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr18_-_53019208 0.19 ENST00000562607.1
TCF4
transcription factor 4
chr3_+_152879985 0.19 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr20_-_18447667 0.18 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1
double zinc ribbon and ankyrin repeat domains 1
chr7_-_92777606 0.18 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr14_-_74551096 0.16 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr10_-_50970322 0.16 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr3_-_141747950 0.15 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_+_242089833 0.14 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
PPP1R7
protein phosphatase 1, regulatory subunit 7
chr19_-_19302931 0.14 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr4_-_57547454 0.13 ENST00000556376.2
HOPX
HOP homeobox
chr5_+_148737562 0.13 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr14_-_82000140 0.13 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr11_-_118023594 0.13 ENST00000529878.1
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr14_+_32798547 0.13 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chrM_+_9207 0.12 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr11_-_33913708 0.11 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_-_152131703 0.11 ENST00000316073.3
RPTN
repetin
chr14_-_74551172 0.11 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr3_+_130569429 0.10 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr10_+_99205894 0.10 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chr5_+_176811431 0.10 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr6_+_26020672 0.10 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr22_+_39916558 0.10 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr19_-_7698599 0.10 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr1_+_160160283 0.09 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_-_180397256 0.09 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr1_+_160160346 0.09 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr10_-_50970382 0.08 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr18_+_32402321 0.08 ENST00000587723.1
DTNA
dystrobrevin, alpha
chrX_+_591524 0.08 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr5_-_147286065 0.08 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr19_+_45973120 0.08 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr17_+_72931876 0.08 ENST00000328801.4
OTOP3
otopetrin 3
chr13_-_30683005 0.07 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chr7_+_1272522 0.07 ENST00000316333.8
UNCX
UNC homeobox
chr6_+_43968306 0.07 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr10_+_99205959 0.07 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16
zinc finger, DHHC-type containing 16
chr1_-_2461684 0.07 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr11_-_18211042 0.07 ENST00000527671.1
RP11-113D6.6
Uncharacterized protein
chr15_+_40733387 0.07 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chrX_-_70326455 0.07 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr7_-_83278322 0.07 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_+_65216462 0.06 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr6_-_100912785 0.06 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr16_+_53164833 0.06 ENST00000564845.1
CHD9
chromodomain helicase DNA binding protein 9
chr6_+_135502501 0.06 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr6_+_39760129 0.06 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr16_+_24741013 0.05 ENST00000315183.7
ENST00000395799.3
TNRC6A
trinucleotide repeat containing 6A
chr19_+_4007644 0.05 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr12_-_94673956 0.05 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr4_-_69111401 0.05 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr2_+_196313239 0.05 ENST00000413290.1
AC064834.1
AC064834.1
chr12_+_81110684 0.05 ENST00000228644.3
MYF5
myogenic factor 5
chr6_-_31088214 0.05 ENST00000376288.2
CDSN
corneodesmosin
chr1_+_110881945 0.04 ENST00000602849.1
ENST00000487146.2
RBM15
RNA binding motif protein 15
chr8_-_18744528 0.04 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr16_+_69345243 0.04 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr4_-_89205350 0.04 ENST00000509340.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr6_-_31782813 0.03 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr1_+_210501589 0.03 ENST00000413764.2
ENST00000541565.1
HHAT
hedgehog acyltransferase
chr1_+_152943122 0.03 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr8_-_42234745 0.03 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr11_-_71823715 0.03 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr1_-_234667504 0.03 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr17_-_39123144 0.03 ENST00000355612.2
KRT39
keratin 39
chr12_-_16759440 0.02 ENST00000537304.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_153599269 0.02 ENST00000463297.1
RP11-217E22.5
RP11-217E22.5
chr18_+_59000815 0.02 ENST00000262717.4
CDH20
cadherin 20, type 2
chr4_+_89206076 0.02 ENST00000500009.2
RP11-10L7.1
RP11-10L7.1
chr11_-_71823796 0.02 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr11_+_75526212 0.02 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr12_+_64798826 0.02 ENST00000540203.1
XPOT
exportin, tRNA
chr17_+_7792101 0.02 ENST00000358181.4
ENST00000330494.7
CHD3
chromodomain helicase DNA binding protein 3
chr7_+_129984630 0.02 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5
carboxypeptidase A5
chr17_-_39211463 0.02 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr6_+_155538093 0.02 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr18_+_6774000 0.02 ENST00000532723.1
ARHGAP28
Rho GTPase activating protein 28
chr16_+_20911174 0.02 ENST00000568663.1
LYRM1
LYR motif containing 1
chr6_+_26199737 0.02 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr20_-_45976816 0.01 ENST00000441977.1
ZMYND8
zinc finger, MYND-type containing 8
chr4_-_186570679 0.01 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr9_-_136933615 0.01 ENST00000371834.2
BRD3
bromodomain containing 3
chr17_-_10017864 0.01 ENST00000323816.4
GAS7
growth arrest-specific 7
chr19_-_7697857 0.01 ENST00000598935.1
PCP2
Purkinje cell protein 2
chr1_-_157746909 0.01 ENST00000392274.3
ENST00000361516.3
ENST00000368181.4
FCRL2
Fc receptor-like 2
chr3_+_119814070 0.01 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr15_-_31393910 0.01 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr14_-_78083112 0.01 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr4_+_71457970 0.01 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr9_+_12693336 0.01 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr1_+_203463245 0.01 ENST00000367222.2
OPTC
opticin
chr11_-_71823266 0.01 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15

Network of associatons between targets according to the STRING database.

First level regulatory network of EN2_GBX2_LBX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.6 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.7 GO:0061055 myotome development(GO:0061055)
0.1 0.3 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 2.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.3 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 2.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 2.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.3 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.3 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.6 GO:0007379 segment specification(GO:0007379)
0.0 0.9 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.5 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 1.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.4 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.0 GO:0003335 corneocyte development(GO:0003335)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 2.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.6 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 1.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.2 3.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.7 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 2.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.7 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 4.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins