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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ETV6

Z-value: 1.25

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Transcription factors associated with ETV6

Gene Symbol Gene ID Gene Info
ETV6
ENSG00000139083.6 ETS variant transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV6hg19_v2_chr12_+_11802753_11802834-0.784.8e-05Click!

Activity profile of ETV6 motif

Sorted Z-values of ETV6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_22351977 3.07 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr3_+_149191723 2.29 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr17_+_77020146 2.25 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr19_+_507299 2.20 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr19_+_6887571 2.18 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr11_-_64851496 2.04 ENST00000404147.3
ENST00000275517.3
CDCA5
cell division cycle associated 5
chr14_-_21852119 2.02 ENST00000555943.1
SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr20_-_2821271 1.99 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr17_+_77020224 1.95 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_77020325 1.83 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr8_+_145133493 1.77 ENST00000316052.5
ENST00000525936.1
EXOSC4
exosome component 4
chr16_-_2205352 1.73 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr17_-_79633590 1.69 ENST00000374741.3
ENST00000571503.1
OXLD1
oxidoreductase-like domain containing 1
chr17_+_18601299 1.69 ENST00000572555.1
ENST00000395902.3
ENST00000449552.2
TRIM16L
tripartite motif containing 16-like
chr8_+_145137489 1.54 ENST00000355091.4
ENST00000525087.1
ENST00000361036.6
ENST00000524418.1
GPAA1
glycosylphosphatidylinositol anchor attachment 1
chr11_+_61560348 1.53 ENST00000535723.1
ENST00000574708.1
FEN1
FADS2
flap structure-specific endonuclease 1
fatty acid desaturase 2
chrX_+_69509927 1.49 ENST00000374403.3
KIF4A
kinesin family member 4A
chr19_+_50919056 1.43 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chr20_-_34542548 1.42 ENST00000305978.2
SCAND1
SCAN domain containing 1
chr17_+_45908974 1.37 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr1_+_38273419 1.36 ENST00000468084.1
C1orf122
chromosome 1 open reading frame 122
chrX_+_47092314 1.35 ENST00000218348.3
USP11
ubiquitin specific peptidase 11
chr20_+_2821366 1.34 ENST00000453689.1
ENST00000417508.1
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr2_-_225907150 1.34 ENST00000258390.7
DOCK10
dedicator of cytokinesis 10
chr16_+_30406423 1.32 ENST00000524644.1
ZNF48
zinc finger protein 48
chr19_-_45681482 1.32 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A
trafficking protein particle complex 6A
chr12_+_54447637 1.32 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr17_+_34958001 1.29 ENST00000250156.7
MRM1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr11_-_67205538 1.25 ENST00000326294.3
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr16_-_54963026 1.23 ENST00000560208.1
ENST00000557792.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chrX_+_69509870 1.20 ENST00000374388.3
KIF4A
kinesin family member 4A
chr1_-_246729544 1.17 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr12_-_58329888 1.17 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr17_-_38574169 1.17 ENST00000423485.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr16_-_31085514 1.11 ENST00000300849.4
ZNF668
zinc finger protein 668
chr2_+_239067597 1.11 ENST00000546354.1
FAM132B
family with sequence similarity 132, member B
chr9_-_139581875 1.10 ENST00000371696.2
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr15_-_51058005 1.10 ENST00000261854.5
SPPL2A
signal peptide peptidase like 2A
chr5_-_137090028 1.10 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr9_-_139581848 1.10 ENST00000538402.1
ENST00000371694.3
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr1_+_203830703 1.09 ENST00000414487.2
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr7_-_95225768 1.09 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr14_+_103566481 1.09 ENST00000380069.3
EXOC3L4
exocyst complex component 3-like 4
chr17_+_49337881 1.09 ENST00000225298.7
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr14_+_103995546 1.08 ENST00000299202.4
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr17_+_48450575 1.05 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1
essential meiotic structure-specific endonuclease 1
chr14_+_103995503 1.04 ENST00000389749.4
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chrX_-_100604184 1.03 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr11_+_47600562 1.01 ENST00000263774.4
ENST00000529276.1
ENST00000528192.1
ENST00000530295.1
ENST00000534208.1
ENST00000534716.2
NDUFS3
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
chr3_-_9834463 0.99 ENST00000439043.1
TADA3
transcriptional adaptor 3
chrX_+_47092791 0.98 ENST00000377080.3
USP11
ubiquitin specific peptidase 11
chr20_-_2821756 0.97 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr11_-_62389621 0.96 ENST00000531383.1
ENST00000265471.5
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr15_-_65282232 0.96 ENST00000416889.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr17_-_4843316 0.95 ENST00000544061.2
SLC25A11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr1_+_156698743 0.95 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr12_+_53693466 0.94 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr9_-_33264557 0.93 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr7_+_6655225 0.93 ENST00000457543.3
ZNF853
zinc finger protein 853
chr15_-_65282274 0.93 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr19_+_50148087 0.93 ENST00000601038.1
ENST00000595242.1
SCAF1
SR-related CTD-associated factor 1
chr16_+_67226019 0.93 ENST00000379378.3
E2F4
E2F transcription factor 4, p107/p130-binding
chr4_+_1723197 0.92 ENST00000485989.2
ENST00000313288.4
TACC3
transforming, acidic coiled-coil containing protein 3
chr5_-_443239 0.92 ENST00000408966.2
C5orf55
chromosome 5 open reading frame 55
chr2_-_3595547 0.92 ENST00000438485.1
RP13-512J5.1
Uncharacterized protein
chr2_-_97523721 0.91 ENST00000393537.4
ANKRD39
ankyrin repeat domain 39
chr5_+_177557997 0.91 ENST00000313386.4
ENST00000515098.1
ENST00000542098.1
ENST00000502814.1
ENST00000507457.1
ENST00000508647.1
RMND5B
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr19_+_56186557 0.90 ENST00000270460.6
EPN1
epsin 1
chr12_-_58329819 0.90 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr12_+_54402790 0.90 ENST00000040584.4
HOXC8
homeobox C8
chr11_-_118966167 0.89 ENST00000530167.1
H2AFX
H2A histone family, member X
chr19_+_49497121 0.88 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chrX_+_153639856 0.88 ENST00000426834.1
ENST00000369790.4
ENST00000454722.1
ENST00000350743.4
ENST00000299328.5
ENST00000351413.4
TAZ
tafazzin
chr6_-_31697977 0.88 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr16_+_30406721 0.86 ENST00000320159.2
ZNF48
zinc finger protein 48
chr2_-_101034070 0.86 ENST00000264249.3
CHST10
carbohydrate sulfotransferase 10
chr14_+_35451880 0.86 ENST00000554803.1
ENST00000555746.1
SRP54
signal recognition particle 54kDa
chr8_+_121457642 0.86 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr11_-_61129306 0.86 ENST00000544118.1
CYB561A3
cytochrome b561 family, member A3
chr20_+_57264187 0.85 ENST00000525967.1
ENST00000525817.1
NPEPL1
aminopeptidase-like 1
chr3_-_49055991 0.85 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALRD3
DALR anticodon binding domain containing 3
chr16_+_66638003 0.85 ENST00000562357.1
ENST00000360086.4
ENST00000562707.1
ENST00000361909.4
ENST00000460097.1
ENST00000565666.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr13_-_76111945 0.85 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr16_+_77225071 0.85 ENST00000439557.2
ENST00000545553.1
MON1B
MON1 secretory trafficking family member B
chr11_+_62538775 0.84 ENST00000294168.3
ENST00000526261.1
TAF6L
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr7_-_72722783 0.84 ENST00000428206.1
ENST00000252594.6
ENST00000310326.8
ENST00000438747.2
NSUN5
NOP2/Sun domain family, member 5
chr17_-_61904420 0.84 ENST00000580272.1
FTSJ3
FtsJ homolog 3 (E. coli)
chr2_+_201981527 0.83 ENST00000441224.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr11_-_31531121 0.83 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr2_+_220462560 0.83 ENST00000456909.1
ENST00000295641.10
STK11IP
serine/threonine kinase 11 interacting protein
chr20_-_3140490 0.82 ENST00000449731.1
ENST00000380266.3
UBOX5
FASTKD5
U-box domain containing 5
FAST kinase domains 5
chr1_+_38273818 0.81 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr15_-_85259360 0.81 ENST00000559729.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr17_-_37844267 0.81 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
PGAP3
post-GPI attachment to proteins 3
chr6_-_31697563 0.80 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_40336969 0.80 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
FBL
fibrillarin
chr6_-_125623046 0.80 ENST00000608295.1
ENST00000398153.2
ENST00000608284.1
ENST00000368377.4
HDDC2
HD domain containing 2
chr19_+_54619125 0.80 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
PRPF31
pre-mRNA processing factor 31
chr20_+_2821340 0.79 ENST00000380445.3
ENST00000380469.3
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr1_-_201438282 0.78 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr11_-_62389449 0.78 ENST00000534026.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr6_-_11382478 0.78 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr9_-_86571628 0.78 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr9_+_37753795 0.77 ENST00000377753.2
ENST00000537911.1
ENST00000377754.2
ENST00000297994.3
TRMT10B
tRNA methyltransferase 10 homolog B (S. cerevisiae)
chr15_+_91260552 0.77 ENST00000355112.3
ENST00000560509.1
BLM
Bloom syndrome, RecQ helicase-like
chr5_-_140027357 0.77 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr10_-_22292675 0.77 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr9_-_37785037 0.76 ENST00000327304.5
ENST00000396521.3
EXOSC3
exosome component 3
chr11_-_47600549 0.76 ENST00000430070.2
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr6_-_31697255 0.76 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr2_-_96971232 0.76 ENST00000323853.5
SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chrX_+_24073048 0.76 ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr12_+_6982725 0.76 ENST00000433346.1
LRRC23
leucine rich repeat containing 23
chr2_+_217363559 0.75 ENST00000600880.1
ENST00000446558.1
RPL37A
ribosomal protein L37a
chr20_+_60962143 0.75 ENST00000343986.4
RPS21
ribosomal protein S21
chr19_-_58892389 0.75 ENST00000427624.2
ENST00000597582.1
ZNF837
zinc finger protein 837
chr17_+_19030782 0.75 ENST00000344415.4
ENST00000577213.1
GRAPL
GRB2-related adaptor protein-like
chr2_+_241544834 0.75 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
GPR35
G protein-coupled receptor 35
chr10_+_99079008 0.75 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr11_+_65770227 0.73 ENST00000527348.1
BANF1
barrier to autointegration factor 1
chr2_+_201981663 0.73 ENST00000433445.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr11_-_62389577 0.73 ENST00000534715.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr11_-_47600320 0.72 ENST00000525720.1
ENST00000531067.1
ENST00000533290.1
ENST00000529499.1
ENST00000529946.1
ENST00000526005.1
ENST00000395288.2
ENST00000534239.1
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr7_-_37488834 0.71 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr19_+_56186606 0.70 ENST00000085079.7
EPN1
epsin 1
chr20_+_3190006 0.69 ENST00000380113.3
ENST00000455664.2
ENST00000399838.3
ITPA
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr9_-_33264676 0.69 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr7_-_37488777 0.69 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chr19_+_49496705 0.69 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr10_-_99161033 0.68 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr17_-_15587602 0.68 ENST00000416464.2
ENST00000578237.1
ENST00000581200.1
TRIM16
tripartite motif containing 16
chr6_+_31620191 0.68 ENST00000375918.2
ENST00000375920.4
APOM
apolipoprotein M
chr1_-_32210275 0.68 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr8_-_131028782 0.67 ENST00000519020.1
FAM49B
family with sequence similarity 49, member B
chr3_+_45635661 0.67 ENST00000440097.1
LIMD1
LIM domains containing 1
chr10_+_89264625 0.66 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr8_-_144655141 0.66 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr17_-_55927370 0.65 ENST00000578444.1
ENST00000313608.8
ENST00000579380.1
MRPS23
mitochondrial ribosomal protein S23
chr17_+_46048497 0.65 ENST00000583352.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr13_+_41363581 0.65 ENST00000338625.4
SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr14_+_96000930 0.65 ENST00000331334.4
GLRX5
glutaredoxin 5
chr14_-_93673353 0.64 ENST00000556566.1
ENST00000306954.4
C14orf142
chromosome 14 open reading frame 142
chr16_-_69373396 0.64 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr1_+_151372010 0.64 ENST00000290541.6
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr19_+_52693259 0.64 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr17_+_7487146 0.64 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr9_-_139010696 0.64 ENST00000418388.1
ENST00000561457.1
C9orf69
chromosome 9 open reading frame 69
chr17_+_79935418 0.63 ENST00000306729.7
ENST00000306739.4
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr19_+_49496782 0.63 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr8_-_121457608 0.63 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr10_+_35415719 0.63 ENST00000474362.1
ENST00000374721.3
CREM
cAMP responsive element modulator
chr2_+_3383439 0.63 ENST00000382110.2
ENST00000324266.5
TRAPPC12
trafficking protein particle complex 12
chr4_+_1723512 0.63 ENST00000493975.1
TACC3
transforming, acidic coiled-coil containing protein 3
chr11_-_61560053 0.62 ENST00000537328.1
TMEM258
transmembrane protein 258
chrX_-_11129229 0.62 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
RP11-120D5.1
chr21_+_38593701 0.61 ENST00000440629.1
AP001432.14
AP001432.14
chr15_-_65281775 0.61 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr17_-_79876010 0.60 ENST00000328666.6
SIRT7
sirtuin 7
chr15_+_91427642 0.60 ENST00000328850.3
ENST00000414248.2
FES
feline sarcoma oncogene
chr17_+_79935464 0.60 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr22_+_40742497 0.60 ENST00000216194.7
ADSL
adenylosuccinate lyase
chr6_-_43496605 0.59 ENST00000455285.2
XPO5
exportin 5
chr11_-_63993601 0.59 ENST00000545812.1
ENST00000394547.3
ENST00000317459.6
TRPT1
tRNA phosphotransferase 1
chr16_-_28937027 0.59 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr2_-_85839146 0.59 ENST00000306336.5
ENST00000409734.3
C2orf68
chromosome 2 open reading frame 68
chr2_+_239335636 0.58 ENST00000409297.1
ASB1
ankyrin repeat and SOCS box containing 1
chr20_+_5931497 0.58 ENST00000378886.2
ENST00000265187.4
MCM8
minichromosome maintenance complex component 8
chr12_+_53693812 0.58 ENST00000549488.1
C12orf10
chromosome 12 open reading frame 10
chr12_-_6798025 0.58 ENST00000542351.1
ENST00000538829.1
ZNF384
zinc finger protein 384
chr17_+_76374714 0.58 ENST00000262764.6
ENST00000589689.1
ENST00000329897.7
ENST00000592043.1
ENST00000587356.1
PGS1
phosphatidylglycerophosphate synthase 1
chr2_-_38829768 0.58 ENST00000378915.3
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr8_-_17555164 0.57 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr12_+_120875910 0.57 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr22_+_40742512 0.57 ENST00000454266.2
ENST00000342312.6
ADSL
adenylosuccinate lyase
chr10_+_22605304 0.56 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr4_+_980785 0.56 ENST00000247933.4
ENST00000453894.1
IDUA
iduronidase, alpha-L-
chr17_+_79650962 0.56 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr16_-_67694597 0.56 ENST00000393919.4
ENST00000219251.8
ACD
adrenocortical dysplasia homolog (mouse)
chr1_-_154934200 0.55 ENST00000368457.2
PYGO2
pygopus family PHD finger 2
chr12_+_132413798 0.55 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
PUS1
pseudouridylate synthase 1
chr5_+_102455853 0.55 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr16_+_66638567 0.55 ENST00000567572.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr19_-_40562063 0.54 ENST00000598845.1
ENST00000593605.1
ENST00000221355.6
ENST00000434248.1
ZNF780B
zinc finger protein 780B
chr19_-_1876156 0.54 ENST00000565797.1
CTB-31O20.2
CTB-31O20.2
chr19_+_56166360 0.54 ENST00000308924.4
U2AF2
U2 small nuclear RNA auxiliary factor 2
chr16_-_420514 0.54 ENST00000199706.8
MRPL28
mitochondrial ribosomal protein L28
chr11_-_63993690 0.53 ENST00000394546.2
ENST00000541278.1
TRPT1
tRNA phosphotransferase 1
chr17_+_7835419 0.53 ENST00000576538.1
ENST00000380262.3
ENST00000563694.1
ENST00000380255.3
ENST00000570782.1
CNTROB
centrobin, centrosomal BRCA2 interacting protein
chr15_-_80263506 0.53 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr11_-_22647350 0.53 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr3_-_122134882 0.53 ENST00000330689.4
WDR5B
WD repeat domain 5B
chr10_-_103454876 0.53 ENST00000331272.7
FBXW4
F-box and WD repeat domain containing 4
chr12_+_132413739 0.53 ENST00000443358.2
PUS1
pseudouridylate synthase 1
chr5_+_179247759 0.52 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr17_+_46048376 0.52 ENST00000338399.4
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr10_+_102729249 0.52 ENST00000519649.1
ENST00000518124.1
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr19_+_45542773 0.52 ENST00000544944.2
CLASRP
CLK4-associating serine/arginine rich protein
chr12_+_50505762 0.52 ENST00000550487.1
ENST00000317943.2
COX14
cytochrome c oxidase assembly homolog 14 (S. cerevisiae)
chr1_-_43855479 0.51 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr19_-_56092187 0.51 ENST00000325421.4
ENST00000592239.1
ZNF579
zinc finger protein 579

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.0 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.7 2.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.5 2.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.5 2.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.4 2.2 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.4 1.2 GO:0019085 early viral transcription(GO:0019085)
0.4 1.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 1.1 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.3 0.9 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.3 0.9 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.3 1.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.3 0.8 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.2 0.7 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.2 1.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.2 1.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.7 GO:0046041 ITP metabolic process(GO:0046041)
0.2 2.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 1.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 0.8 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.2 0.6 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.2 1.3 GO:1903232 melanosome assembly(GO:1903232)
0.2 3.9 GO:0031167 rRNA methylation(GO:0031167)
0.2 0.3 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2 0.7 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2 0.5 GO:0036451 cap mRNA methylation(GO:0036451)
0.2 0.5 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.2 0.6 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 0.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 0.5 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.6 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.5 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 2.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 0.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.8 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.4 GO:0018307 enzyme active site formation(GO:0018307)
0.1 0.8 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.4 GO:0032618 interleukin-15 production(GO:0032618)
0.1 1.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.5 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 2.4 GO:0006527 arginine catabolic process(GO:0006527)
0.1 1.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 2.3 GO:0051601 exocyst localization(GO:0051601)
0.1 0.4 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.8 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 1.9 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 1.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 1.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 2.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.6 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 1.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.6 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 0.3 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.6 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 3.4 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1 0.5 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.4 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 1.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.2 GO:2000395 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 1.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 2.4 GO:0001510 RNA methylation(GO:0001510)
0.0 0.8 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.4 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.5 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.4 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 1.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.8 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.2 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 2.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.9 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.9 GO:0030539 male genitalia development(GO:0030539)
0.0 0.2 GO:0060179 male mating behavior(GO:0060179)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 3.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 1.0 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.7 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 1.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.5 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.4 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 1.8 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 1.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.3 GO:0045008 depyrimidination(GO:0045008)
0.0 0.6 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 1.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0014894 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.1 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0035101 FACT complex(GO:0035101)
0.4 1.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.3 1.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 0.9 GO:0034657 GID complex(GO:0034657)
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 0.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 1.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.2 1.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.2 2.2 GO:0097255 R2TP complex(GO:0097255)
0.2 0.6 GO:0042565 RNA nuclear export complex(GO:0042565)
0.2 1.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 1.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 2.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 2.6 GO:0030914 STAGA complex(GO:0030914)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.5 GO:0044753 amphisome(GO:0044753)
0.1 2.0 GO:0008278 cohesin complex(GO:0008278)
0.1 0.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.5 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 2.1 GO:0030897 HOPS complex(GO:0030897)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.7 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.3 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 3.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.9 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.4 GO:0032044 DSIF complex(GO:0032044)
0.1 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 6.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.8 GO:0000800 lateral element(GO:0000800)
0.0 2.9 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 2.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 2.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.8 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 2.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 1.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.5 2.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.5 2.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.4 1.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.4 1.1 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.4 2.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 2.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.3 2.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3 1.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.3 0.9 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.3 1.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 0.8 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.3 1.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) linoleoyl-CoA desaturase activity(GO:0016213) 5'-flap endonuclease activity(GO:0017108)
0.2 2.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 1.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 0.7 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.2 0.6 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.2 1.0 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 0.6 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.2 1.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 0.8 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.2 0.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 1.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.6 GO:0070990 snRNP binding(GO:0070990)
0.1 0.5 GO:0003896 DNA primase activity(GO:0003896)
0.1 1.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.7 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 2.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.8 GO:0000403 Y-form DNA binding(GO:0000403) four-way junction helicase activity(GO:0009378)
0.1 1.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.3 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 3.3 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 1.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 1.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.4 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 6.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 1.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.6 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.5 PID MYC PATHWAY C-MYC pathway
0.0 2.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 6.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 2.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.5 PID AURORA A PATHWAY Aurora A signaling
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.7 REACTOME KINESINS Genes involved in Kinesins
0.1 1.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.4 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1 2.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 2.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 2.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.9 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway