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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EVX2

Z-value: 0.23

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Transcription factors associated with EVX2

Gene Symbol Gene ID Gene Info
ENSG00000174279.4 even-skipped homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EVX2hg19_v2_chr2_-_176948641_1769486410.136.0e-01Click!

Activity profile of EVX2 motif

Sorted Z-values of EVX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_65554493 0.69 ENST00000335987.3
ovo-like zinc finger 1
chr19_+_11071546 0.62 ENST00000358026.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr3_+_111717511 0.62 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr3_+_111718036 0.51 ENST00000455401.2
transgelin 3
chr3_+_111717600 0.46 ENST00000273368.4
transgelin 3
chr18_-_33709268 0.44 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chr4_+_144354644 0.33 ENST00000512843.1
GRB2-associated binding protein 1
chr4_+_144312659 0.31 ENST00000509992.1
GRB2-associated binding protein 1
chr3_+_111718173 0.28 ENST00000494932.1
transgelin 3
chr6_-_111927449 0.25 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3 interacting protein 2
chr16_+_53133070 0.24 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr6_-_111927062 0.20 ENST00000359831.4
TRAF3 interacting protein 2
chr12_+_64798826 0.15 ENST00000540203.1
exportin, tRNA
chr17_+_18086392 0.12 ENST00000541285.1
alkB, alkylation repair homolog 5 (E. coli)
chr15_-_55562451 0.11 ENST00000568803.1
RAB27A, member RAS oncogene family
chr4_-_41884582 0.07 ENST00000499082.2
long intergenic non-protein coding RNA 682
chr1_-_151431674 0.06 ENST00000531094.1
pogo transposable element with ZNF domain
chr19_-_47137942 0.04 ENST00000300873.4
guanine nucleotide binding protein (G protein), gamma 8
chr3_-_48659193 0.04 ENST00000330862.3
transmembrane protein 89
chr1_-_151431647 0.04 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
pogo transposable element with ZNF domain
chr1_+_160160346 0.03 ENST00000368078.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_160160283 0.03 ENST00000368079.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr4_-_41884620 0.03 ENST00000504870.1
long intergenic non-protein coding RNA 682
chr6_-_62996066 0.03 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr20_+_30467600 0.02 ENST00000375934.4
ENST00000375922.4
tubulin tyrosine ligase-like family, member 9
chr6_+_39760129 0.01 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr2_-_8715616 0.00 ENST00000418358.1
AC011747.3

Network of associatons between targets according to the STRING database.

First level regulatory network of EVX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.6 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters