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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EZH2

Z-value: 1.45

Motif logo

Transcription factors associated with EZH2

Gene Symbol Gene ID Gene Info
ENSG00000106462.6 enhancer of zeste 2 polycomb repressive complex 2 subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EZH2hg19_v2_chr7_-_148581251_148581347-0.852.2e-06Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_48326764 6.38 ENST00000413668.1
ENST00000441948.1
solute carrier family 38, member 5
chr12_-_6484376 6.30 ENST00000360168.3
ENST00000358945.3
sodium channel, non-voltage-gated 1 alpha subunit
chr10_-_105845674 6.24 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr12_-_6483969 5.61 ENST00000396966.2
sodium channel, non-voltage-gated 1 alpha subunit
chr14_+_23305760 5.59 ENST00000311852.6
matrix metallopeptidase 14 (membrane-inserted)
chr1_+_209859510 5.53 ENST00000367028.2
ENST00000261465.1
hydroxysteroid (11-beta) dehydrogenase 1
chr19_-_51456344 5.52 ENST00000336334.3
ENST00000593428.1
kallikrein-related peptidase 5
chr1_+_86889769 4.97 ENST00000370565.4
chloride channel accessory 2
chr7_-_41740181 4.95 ENST00000442711.1
inhibin, beta A
chr10_-_105845536 4.28 ENST00000393211.3
collagen, type XVII, alpha 1
chr1_-_153588765 4.26 ENST00000368701.1
ENST00000344616.2
S100 calcium binding protein A14
chr3_-_195538760 3.94 ENST00000475231.1
mucin 4, cell surface associated
chr3_-_195538728 3.67 ENST00000349607.4
ENST00000346145.4
mucin 4, cell surface associated
chr15_+_43885252 3.45 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr2_+_210288760 3.25 ENST00000199940.6
microtubule-associated protein 2
chrX_-_48326683 3.22 ENST00000440085.1
solute carrier family 38, member 5
chr2_-_113594279 3.21 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr16_-_31146961 3.19 ENST00000567531.1
protease, serine, 8
chr1_-_153588334 3.15 ENST00000476873.1
S100 calcium binding protein A14
chr19_-_4338783 3.09 ENST00000601482.1
ENST00000600324.1
signal transducing adaptor family member 2
chrX_-_48328631 3.04 ENST00000429543.1
ENST00000317669.5
solute carrier family 38, member 5
chr11_-_104905840 2.99 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr6_+_106959718 2.96 ENST00000369066.3
absent in melanoma 1
chr1_+_152881014 2.94 ENST00000368764.3
ENST00000392667.2
involucrin
chr3_+_193853927 2.86 ENST00000232424.3
hes family bHLH transcription factor 1
chr15_+_43985084 2.82 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr12_-_6484715 2.57 ENST00000228916.2
sodium channel, non-voltage-gated 1 alpha subunit
chrX_-_48328551 2.51 ENST00000376876.3
solute carrier family 38, member 5
chr1_-_182361327 2.50 ENST00000331872.6
ENST00000311223.5
glutamate-ammonia ligase
chr2_+_169926047 2.49 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr1_-_209824643 2.48 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr19_-_36001286 2.35 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
dermokine
chr15_+_43886057 2.34 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
creatine kinase, mitochondrial 1B
chr15_+_43885799 2.32 ENST00000449946.1
ENST00000417289.1
creatine kinase, mitochondrial 1B
chr19_+_35607166 2.27 ENST00000604255.1
ENST00000346446.5
ENST00000344013.6
ENST00000603449.1
ENST00000406988.1
ENST00000605550.1
ENST00000604804.1
ENST00000605552.1
FXYD domain containing ion transport regulator 3
chrX_+_99899180 2.24 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr19_-_36004543 2.18 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
dermokine
chr8_+_102504651 2.18 ENST00000251808.3
ENST00000521085.1
grainyhead-like 2 (Drosophila)
chr1_+_145439306 2.16 ENST00000425134.1
thioredoxin interacting protein
chr19_+_35606692 2.15 ENST00000406242.3
ENST00000454903.2
FXYD domain containing ion transport regulator 3
chr16_-_31147020 2.14 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
protease, serine, 8
chr3_+_189507460 2.10 ENST00000434928.1
tumor protein p63
chr15_-_45422056 2.08 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
dual oxidase maturation factor 1
chr8_-_49834299 2.00 ENST00000396822.1
snail family zinc finger 2
chr12_-_28125638 1.98 ENST00000545234.1
parathyroid hormone-like hormone
chr9_+_130911723 1.97 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr4_-_80994210 1.95 ENST00000403729.2
anthrax toxin receptor 2
chr11_+_118401899 1.95 ENST00000528373.1
ENST00000544878.1
ENST00000354284.4
ENST00000533137.1
ENST00000532762.1
ENST00000526973.1
ENST00000354064.7
ENST00000533102.1
ENST00000313236.5
ENST00000527267.1
ENST00000524725.1
ENST00000533689.1
transmembrane protein 25
chr15_+_43986069 1.92 ENST00000415044.1
creatine kinase, mitochondrial 1A
chr18_+_29027696 1.91 ENST00000257189.4
desmoglein 3
chr3_+_189507523 1.85 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chr19_-_51504852 1.85 ENST00000391806.2
ENST00000347619.4
ENST00000291726.7
ENST00000320838.5
kallikrein-related peptidase 8
chr1_-_182360918 1.84 ENST00000339526.4
glutamate-ammonia ligase
chr5_-_151066514 1.84 ENST00000538026.1
ENST00000522348.1
ENST00000521569.1
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_-_121379739 1.77 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr2_-_214014959 1.74 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKAROS family zinc finger 2 (Helios)
chr11_+_35222629 1.73 ENST00000526553.1
CD44 molecule (Indian blood group)
chr11_-_119993734 1.72 ENST00000533302.1
tripartite motif containing 29
chr14_+_23305783 1.70 ENST00000547279.1
matrix metallopeptidase 14 (membrane-inserted)
chr19_-_51456321 1.70 ENST00000391809.2
kallikrein-related peptidase 5
chr22_-_31688381 1.69 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr6_+_30848771 1.67 ENST00000503180.1
discoidin domain receptor tyrosine kinase 1
chr4_-_80994619 1.66 ENST00000404191.1
anthrax toxin receptor 2
chr3_-_195310802 1.65 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr17_+_7387677 1.64 ENST00000322644.6
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr5_-_141249154 1.61 ENST00000357517.5
ENST00000536585.1
protocadherin 1
chr3_+_189507432 1.60 ENST00000354600.5
tumor protein p63
chr8_-_49833978 1.59 ENST00000020945.1
snail family zinc finger 2
chr9_+_71820057 1.58 ENST00000539225.1
tight junction protein 2
chr4_+_30721968 1.58 ENST00000361762.2
protocadherin 7
chr8_+_97506033 1.56 ENST00000518385.1
syndecan 2
chr22_-_31688431 1.55 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr6_-_47010061 1.52 ENST00000371253.2
G protein-coupled receptor 110
chr6_+_31895467 1.52 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr2_+_228678550 1.52 ENST00000409189.3
ENST00000358813.4
chemokine (C-C motif) ligand 20
chr16_-_79634595 1.51 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr9_+_71819927 1.51 ENST00000535702.1
tight junction protein 2
chr19_-_35992780 1.49 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
dermokine
chr4_-_80994471 1.49 ENST00000295465.4
anthrax toxin receptor 2
chr19_-_4338838 1.47 ENST00000594605.1
signal transducing adaptor family member 2
chr5_-_141257954 1.46 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
protocadherin 1
chr11_+_35211511 1.46 ENST00000524922.1
CD44 molecule (Indian blood group)
chr19_-_49371711 1.46 ENST00000355496.5
ENST00000263265.6
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr1_+_154193325 1.46 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr18_+_47088401 1.45 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr17_-_7387524 1.44 ENST00000311403.4
zinc finger and BTB domain containing 4
chr6_-_134639180 1.43 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr6_-_31550192 1.42 ENST00000429299.2
ENST00000446745.2
lymphotoxin beta (TNF superfamily, member 3)
chr10_+_20105157 1.39 ENST00000377242.3
ENST00000377252.4
plexin domain containing 2
chr15_+_43985725 1.39 ENST00000413453.2
creatine kinase, mitochondrial 1A
chr5_+_145317356 1.39 ENST00000511217.1
SH3 domain containing ring finger 2
chr11_-_119599794 1.38 ENST00000264025.3
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr11_-_102826434 1.32 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr19_+_45973120 1.32 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr19_-_54676884 1.32 ENST00000376591.4
transmembrane channel-like 4
chr3_-_107777208 1.32 ENST00000398258.3
CD47 molecule
chr3_+_111717511 1.30 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr6_+_30848829 1.29 ENST00000508317.1
discoidin domain receptor tyrosine kinase 1
chr6_+_31895480 1.29 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chrY_+_15418467 1.28 ENST00000595988.1
Uncharacterized protein
chr15_+_31508174 1.28 ENST00000559292.2
ENST00000557928.1
RP11-16E12.1
chr9_+_124062071 1.28 ENST00000373818.4
gelsolin
chr11_+_65554493 1.27 ENST00000335987.3
ovo-like zinc finger 1
chr18_-_61329118 1.27 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr6_+_31543334 1.26 ENST00000449264.2
tumor necrosis factor
chr11_+_12302492 1.26 ENST00000533534.1
MICAL C-terminal like
chr6_-_56507586 1.25 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
dystonin
chr17_-_39216344 1.25 ENST00000391418.2
keratin associated protein 2-3
chr1_-_46598371 1.25 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr6_+_144665237 1.25 ENST00000421035.2
utrophin
chr2_+_220325441 1.24 ENST00000396688.1
SPEG complex locus
chr17_-_8055747 1.24 ENST00000317276.4
ENST00000581703.1
period circadian clock 1
chr12_+_56477093 1.24 ENST00000549672.1
ENST00000415288.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_-_46598284 1.23 ENST00000423209.1
ENST00000262741.5
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr4_+_24797085 1.23 ENST00000382120.3
superoxide dismutase 3, extracellular
chr19_-_51522955 1.21 ENST00000358789.3
kallikrein-related peptidase 10
chr13_+_78109804 1.20 ENST00000535157.1
sciellin
chr6_-_47009996 1.19 ENST00000371243.2
G protein-coupled receptor 110
chr6_-_79944336 1.19 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr11_-_104972158 1.19 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr1_+_6511651 1.18 ENST00000434576.1
espin
chr6_-_32145861 1.16 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr6_-_134639042 1.16 ENST00000461976.2
serum/glucocorticoid regulated kinase 1
chr2_+_63277927 1.15 ENST00000282549.2
orthodenticle homeobox 1
chr4_-_159094194 1.15 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr11_-_8832182 1.14 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
suppression of tumorigenicity 5
chr5_+_167181917 1.13 ENST00000519204.1
teneurin transmembrane protein 2
chr15_+_42651691 1.11 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
calpain 3, (p94)
chr13_+_78109884 1.11 ENST00000377246.3
ENST00000349847.3
sciellin
chr4_+_74735102 1.11 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr2_+_66662249 1.11 ENST00000560281.2
Meis homeobox 1
chr6_-_75915757 1.10 ENST00000322507.8
collagen, type XII, alpha 1
chr1_+_6508100 1.10 ENST00000461727.1
espin
chr17_-_48278983 1.09 ENST00000225964.5
collagen, type I, alpha 1
chr1_-_161046266 1.07 ENST00000453926.2
poliovirus receptor-related 4
chr3_+_9944492 1.06 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
interleukin 17 receptor E
chr19_-_36019123 1.05 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chrX_-_153141434 1.05 ENST00000407935.2
ENST00000439496.1
L1 cell adhesion molecule
chr7_+_69064300 1.05 ENST00000342771.4
autism susceptibility candidate 2
chr11_-_124622134 1.05 ENST00000326621.5
V-set and immunoglobulin domain containing 2
chr5_-_73937244 1.05 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr5_-_142077569 1.03 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr11_+_131240373 1.03 ENST00000374791.3
ENST00000436745.1
neurotrimin
chr5_+_9546306 1.03 ENST00000508179.1
small nucleolar RNA host gene 18 (non-protein coding)
chr2_+_208104497 1.00 ENST00000430494.1
AC007879.7
chr7_+_20370300 0.99 ENST00000537992.1
integrin, beta 8
chr3_+_118892362 0.98 ENST00000497685.1
ENST00000264234.3
uroplakin 1B
chr3_-_9291063 0.98 ENST00000383836.3
SLIT-ROBO Rho GTPase activating protein 3
chr15_+_44084503 0.98 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr11_+_18230727 0.98 ENST00000527059.1
Putative mitochondrial carrier protein LOC494141
chr2_+_210444748 0.98 ENST00000392194.1
microtubule-associated protein 2
chr11_+_65779283 0.97 ENST00000312134.2
cystatin E/M
chr14_-_23623577 0.96 ENST00000422941.2
ENST00000453702.1
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr20_-_62168672 0.96 ENST00000217185.2
protein tyrosine kinase 6
chr19_+_41497178 0.96 ENST00000324071.4
cytochrome P450, family 2, subfamily B, polypeptide 6
chr7_+_20370746 0.94 ENST00000222573.4
integrin, beta 8
chr8_-_116680208 0.94 ENST00000517323.2
ENST00000520276.1
trichorhinophalangeal syndrome I
chr3_-_99569821 0.93 ENST00000487087.1
filamin A interacting protein 1-like
chr1_+_154193643 0.93 ENST00000456325.1
ubiquitin associated protein 2-like
chr1_+_47489240 0.93 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr6_-_10413112 0.93 ENST00000465858.1
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr20_-_62168714 0.92 ENST00000542869.1
protein tyrosine kinase 6
chr16_-_65155833 0.91 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr9_+_71736177 0.91 ENST00000606364.1
ENST00000453658.2
tight junction protein 2
chr1_+_95975672 0.90 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
chr6_-_167276033 0.90 ENST00000503859.1
ENST00000506565.1
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_+_128563652 0.90 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_2794750 0.89 ENST00000452765.2
ENST00000389838.2
SH3-domain binding protein 2
chr6_+_46620705 0.89 ENST00000452689.2
solute carrier family 25, member 27
chr11_+_64008525 0.88 ENST00000449942.2
FK506 binding protein 2, 13kDa
chr2_-_216003127 0.88 ENST00000412081.1
ENST00000272895.7
ATP-binding cassette, sub-family A (ABC1), member 12
chr10_+_11047259 0.88 ENST00000379261.4
ENST00000416382.2
CUGBP, Elav-like family member 2
chr10_+_135340859 0.88 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr4_+_106067943 0.88 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
tet methylcytosine dioxygenase 2
chr6_-_41130841 0.87 ENST00000373122.4
triggering receptor expressed on myeloid cells 2
chr12_-_49418407 0.87 ENST00000526209.1
lysine (K)-specific methyltransferase 2D
chr14_-_21270995 0.86 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr13_-_45048386 0.86 ENST00000472477.1
TSC22 domain family, member 1
chr10_-_77161650 0.86 ENST00000372524.4
zinc finger protein 503
chr1_+_155023757 0.86 ENST00000356955.2
ENST00000449910.2
ENST00000359280.4
ENST00000360674.4
ENST00000368412.3
ENST00000355956.2
ENST00000368410.2
ENST00000271836.6
ENST00000368413.1
ENST00000531455.1
ENST00000447332.3
ADAM metallopeptidase domain 15
chr1_-_150780757 0.86 ENST00000271651.3
cathepsin K
chr11_-_111781554 0.86 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr12_+_10331605 0.85 ENST00000298530.3
transmembrane protein 52B
chr18_+_72167096 0.85 ENST00000324301.8
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr5_-_24645078 0.85 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr8_+_128748308 0.84 ENST00000377970.2
v-myc avian myelocytomatosis viral oncogene homolog
chr10_+_11206925 0.83 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CUGBP, Elav-like family member 2
chr9_-_71869642 0.83 ENST00000600472.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr14_-_65569244 0.83 ENST00000557277.1
ENST00000556892.1
MYC associated factor X
chr1_-_27481401 0.83 ENST00000263980.3
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr3_-_112360116 0.83 ENST00000206423.3
ENST00000439685.2
coiled-coil domain containing 80
chr2_+_220299547 0.82 ENST00000312358.7
SPEG complex locus
chr1_-_205391178 0.81 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr14_-_94443105 0.81 ENST00000555019.1
ankyrin repeat and SOCS box containing 2
chrX_-_50386648 0.81 ENST00000460112.3
shroom family member 4
chr1_+_35225339 0.81 ENST00000339480.1
gap junction protein, beta 4, 30.3kDa
chrX_+_105969893 0.81 ENST00000255499.2
ring finger protein 128, E3 ubiquitin protein ligase
chr6_-_10415218 0.80 ENST00000466073.1
ENST00000498450.1
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_36584662 0.80 ENST00000431231.2
ENST00000437668.3
Rho GTPase activating protein 23
chr4_+_2794785 0.80 ENST00000503219.1
SH3-domain binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.4 5.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.2 7.2 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.2 3.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.1 4.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.0 4.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.0 2.9 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.9 6.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.8 15.2 GO:0015816 glycine transport(GO:0015816)
0.7 7.2 GO:1990834 response to odorant(GO:1990834)
0.7 2.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.6 3.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.6 7.1 GO:0070487 monocyte aggregation(GO:0070487)
0.6 2.9 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5 1.5 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 1.5 GO:0001172 transcription, RNA-templated(GO:0001172)
0.4 1.8 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.4 0.9 GO:0010193 response to ozone(GO:0010193)
0.4 4.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.4 1.3 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.4 0.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.4 0.4 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.4 2.0 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4 1.6 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.4 2.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.4 6.1 GO:0006600 creatine metabolic process(GO:0006600)
0.4 13.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 1.7 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.3 2.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 0.3 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.3 1.3 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.3 1.3 GO:0035425 autocrine signaling(GO:0035425)
0.3 7.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.3 1.8 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.3 2.4 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.3 0.9 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 0.9 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3 1.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.3 1.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 1.1 GO:0044691 tooth eruption(GO:0044691)
0.3 7.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 1.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 1.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.3 1.8 GO:0031642 negative regulation of myelination(GO:0031642)
0.3 2.9 GO:2000662 interleukin-5 secretion(GO:0072603) regulation of interleukin-5 secretion(GO:2000662) positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.3 1.3 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.3 0.8 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 1.0 GO:2000683 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) regulation of cellular response to X-ray(GO:2000683) positive regulation of cellular response to X-ray(GO:2000685)
0.2 2.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 1.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 0.7 GO:0086044 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.2 0.7 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.2 1.7 GO:0008218 bioluminescence(GO:0008218)
0.2 1.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 0.7 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 1.5 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.2 2.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 2.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 0.2 GO:0048565 digestive tract development(GO:0048565)
0.2 0.8 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.2 5.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 3.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 13.5 GO:0055078 sodium ion homeostasis(GO:0055078)
0.2 0.5 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 1.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.2 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.7 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.5 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 1.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 1.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.2 0.9 GO:0001555 oocyte growth(GO:0001555)
0.2 1.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 2.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.2 0.5 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 2.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 0.6 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.6 GO:0052361 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 2.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.5 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.3 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 0.5 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.1 0.5 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.6 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 1.0 GO:0003383 apical constriction(GO:0003383)
0.1 0.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.8 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.4 GO:0060168 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 1.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.7 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 2.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.4 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.6 GO:0018032 protein amidation(GO:0018032)
0.1 0.4 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 8.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.4 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 2.2 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 1.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 5.6 GO:1901998 toxin transport(GO:1901998)
0.1 0.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.1 GO:0042048 olfactory behavior(GO:0042048)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.5 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.3 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 1.8 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.2 GO:0007493 endodermal cell fate determination(GO:0007493)
0.1 1.7 GO:0008228 opsonization(GO:0008228)
0.1 0.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 1.2 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1 0.8 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.7 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 1.0 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 0.3 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.5 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 1.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.9 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.7 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.1 1.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.5 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.0 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) axon midline choice point recognition(GO:0016199) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.3 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.5 GO:0032439 endosome localization(GO:0032439)
0.1 0.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.9 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.5 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 2.0 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.2 GO:0061055 myotome development(GO:0061055)
0.1 0.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.8 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 9.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.5 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 1.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 1.9 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:0072553 terminal button organization(GO:0072553)
0.1 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 2.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.7 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.2 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 2.5 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.7 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.5 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:2000523 negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.0 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 0.5 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.4 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 1.2 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.6 GO:0015871 choline transport(GO:0015871)
0.0 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.4 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 3.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571) response to hydroxyisoflavone(GO:0033594)
0.0 2.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0042770 signal transduction in response to DNA damage(GO:0042770)
0.0 0.7 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 0.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.0 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.5 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.0 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 2.0 GO:0030816 positive regulation of cAMP metabolic process(GO:0030816)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0030282 bone mineralization(GO:0030282)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.6 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.3 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.0 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 1.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 2.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.2 GO:0072584 caveolin-mediated endocytosis(GO:0072584)
0.0 0.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.3 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.3 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.6 GO:0035065 regulation of histone acetylation(GO:0035065)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
1.2 8.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.7 7.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.6 1.9 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.6 4.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.6 4.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.5 1.0 GO:0008091 spectrin(GO:0008091)
0.5 3.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.4 13.9 GO:0034706 sodium channel complex(GO:0034706)
0.4 11.8 GO:0030056 hemidesmosome(GO:0030056)
0.4 1.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.4 1.1 GO:0005584 collagen type I trimer(GO:0005584)
0.2 2.5 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.5 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 1.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 3.4 GO:0045179 apical cortex(GO:0045179)
0.2 0.8 GO:0072534 perineuronal net(GO:0072534)
0.2 0.7 GO:0031592 centrosomal corona(GO:0031592)
0.2 1.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 4.7 GO:0097386 glial cell projection(GO:0097386)
0.1 2.3 GO:0032426 stereocilium tip(GO:0032426)
0.1 2.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.9 GO:0036021 endolysosome lumen(GO:0036021)
0.1 8.3 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 5.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 1.4 GO:0030478 actin cap(GO:0030478)
0.1 5.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 1.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.3 GO:0098576 lumenal side of membrane(GO:0098576)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.1 3.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.3 GO:0070938 contractile ring(GO:0070938)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 8.9 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.2 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 1.5 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.0 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 3.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.4 GO:0045095 keratin filament(GO:0045095)
0.0 3.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 1.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 1.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 2.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 4.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.6 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.1 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 3.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 1.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 17.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.5 7.5 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
1.1 4.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.1 3.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.0 15.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.8 4.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.8 14.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.6 1.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 6.1 GO:0004111 creatine kinase activity(GO:0004111)
0.5 1.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 1.5 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.4 0.8 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.3 5.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.3 1.5 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.3 0.8 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.3 1.0 GO:0035501 MH1 domain binding(GO:0035501)
0.2 0.7 GO:0086078 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.2 7.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.9 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 3.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 4.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 1.0 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 0.7 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.2 2.5 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 1.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 6.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 0.5 GO:0016882 cyclo-ligase activity(GO:0016882) 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.2 4.2 GO:0050700 CARD domain binding(GO:0050700)
0.2 2.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 2.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 3.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 4.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 10.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 7.3 GO:0042379 chemokine receptor binding(GO:0042379)
0.1 0.5 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 1.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.9 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.4 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 3.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.4 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 3.9 GO:0001848 complement binding(GO:0001848)
0.1 4.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.7 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.6 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 1.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 1.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.2 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.4 GO:0045159 myosin II binding(GO:0045159)
0.1 0.4 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.3 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.3 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.7 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 3.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.5 GO:0042835 BRE binding(GO:0042835)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.3 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 4.9 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 2.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 1.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.6 GO:0015288 porin activity(GO:0015288)
0.0 0.8 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 1.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 1.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 2.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 9.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 1.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 4.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.4 GO:0004175 endopeptidase activity(GO:0004175)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.7 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 12.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 7.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 10.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.0 PID MYC PATHWAY C-MYC pathway
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 5.9 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 2.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 2.9 PID IGF1 PATHWAY IGF1 pathway
0.1 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 4.3 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.3 PID FOXO PATHWAY FoxO family signaling
0.0 3.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 ST ADRENERGIC Adrenergic Pathway
0.0 1.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 11.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.6 PID P73PATHWAY p73 transcription factor network
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 6.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 0.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.2 6.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 4.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 7.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 7.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 10.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 12.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 5.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 0.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 5.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 11.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.0 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 2.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 3.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex