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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FIGLA

Z-value: 0.47

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Transcription factors associated with FIGLA

Gene Symbol Gene ID Gene Info
FIGLA
ENSG00000183733.6 folliculogenesis specific bHLH transcription factor

Activity profile of FIGLA motif

Sorted Z-values of FIGLA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_18391708 1.72 ENST00000600972.1
JUND
jun D proto-oncogene
chr12_+_52450298 1.43 ENST00000550582.2
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr11_-_117698787 1.31 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr2_-_42160486 1.26 ENST00000427054.1
AC104654.2
AC104654.2
chr11_-_117698765 1.08 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chrX_-_153775426 1.03 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr19_+_54385439 1.02 ENST00000536044.1
ENST00000540413.1
ENST00000263431.3
ENST00000419486.1
PRKCG
protein kinase C, gamma
chr14_+_75746781 1.02 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr19_-_46272106 0.95 ENST00000560168.1
SIX5
SIX homeobox 5
chrX_-_30326445 0.94 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr14_+_75746340 0.93 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr12_+_122150646 0.85 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr3_+_49059038 0.84 ENST00000451378.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr16_-_74808710 0.81 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr20_-_22566089 0.80 ENST00000377115.4
FOXA2
forkhead box A2
chr14_+_31343747 0.77 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
COCH
cochlin
chr16_+_30006997 0.77 ENST00000304516.7
INO80E
INO80 complex subunit E
chr16_+_30006615 0.76 ENST00000563197.1
INO80E
INO80 complex subunit E
chr16_-_2260834 0.75 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chr6_-_31550192 0.75 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr22_-_50970506 0.75 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr4_-_140223670 0.74 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr15_+_89182156 0.74 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr22_+_22988816 0.73 ENST00000480559.1
ENST00000448514.1
GGTLC2
gamma-glutamyltransferase light chain 2
chr6_-_31697255 0.71 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_-_167905225 0.70 ENST00000367846.4
MPC2
mitochondrial pyruvate carrier 2
chr17_+_73521763 0.70 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr16_-_57513657 0.70 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr9_-_116861337 0.69 ENST00000374118.3
KIF12
kinesin family member 12
chr17_+_27895609 0.68 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr14_+_75746664 0.68 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr5_-_132948216 0.67 ENST00000265342.7
FSTL4
follistatin-like 4
chr15_+_89182178 0.67 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr4_-_140223614 0.67 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr9_+_90112767 0.66 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr2_+_37571845 0.63 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr7_-_11871815 0.63 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr16_-_30006922 0.63 ENST00000564026.1
HIRIP3
HIRA interacting protein 3
chr7_+_128784712 0.63 ENST00000289407.4
TSPAN33
tetraspanin 33
chr2_+_37571717 0.61 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr4_-_139163491 0.60 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr19_+_55996565 0.60 ENST00000587400.1
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr15_+_89181974 0.60 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr14_-_37051798 0.59 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr5_+_139027877 0.57 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr17_+_68165657 0.56 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr19_-_50316423 0.56 ENST00000528094.1
ENST00000526575.1
FUZ
fuzzy planar cell polarity protein
chr1_+_66258846 0.55 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr19_-_50316517 0.55 ENST00000313777.4
ENST00000445575.2
FUZ
fuzzy planar cell polarity protein
chr2_+_228029281 0.55 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr6_-_31697563 0.54 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr11_-_66115032 0.54 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr11_+_118958689 0.53 ENST00000535253.1
ENST00000392841.1
HMBS
hydroxymethylbilane synthase
chr19_-_18392422 0.52 ENST00000252818.3
JUND
jun D proto-oncogene
chr19_-_9968816 0.52 ENST00000590841.1
OLFM2
olfactomedin 2
chr19_+_18794470 0.52 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chrX_+_70443050 0.52 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr20_+_5986756 0.51 ENST00000452938.1
CRLS1
cardiolipin synthase 1
chr19_-_7939319 0.51 ENST00000539422.1
CTD-3193O13.9
Protein FLJ22184
chr7_-_27196267 0.50 ENST00000242159.3
HOXA7
homeobox A7
chr2_-_152590946 0.50 ENST00000172853.10
NEB
nebulin
chr20_+_44441215 0.50 ENST00000356455.4
ENST00000405520.1
UBE2C
ubiquitin-conjugating enzyme E2C
chr3_+_32280159 0.50 ENST00000458535.2
ENST00000307526.3
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr7_+_74379083 0.49 ENST00000361825.7
GATSL1
GATS protein-like 1
chr17_+_4618734 0.49 ENST00000571206.1
ARRB2
arrestin, beta 2
chr2_-_28113965 0.48 ENST00000302188.3
RBKS
ribokinase
chr6_-_39197226 0.48 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr19_-_50316489 0.48 ENST00000533418.1
FUZ
fuzzy planar cell polarity protein
chr20_+_5986727 0.47 ENST00000378863.4
CRLS1
cardiolipin synthase 1
chr15_-_45670924 0.47 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_-_159739532 0.46 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr20_+_44441304 0.46 ENST00000352551.5
UBE2C
ubiquitin-conjugating enzyme E2C
chr1_-_11120057 0.46 ENST00000376957.2
SRM
spermidine synthase
chr10_-_69991865 0.45 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr10_+_94608245 0.43 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr14_-_92413727 0.43 ENST00000267620.10
FBLN5
fibulin 5
chr6_-_33160231 0.43 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr1_+_10509971 0.43 ENST00000320498.4
CORT
cortistatin
chr2_-_220436248 0.42 ENST00000265318.4
OBSL1
obscurin-like 1
chr2_-_225811747 0.41 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr19_+_14017003 0.40 ENST00000318003.7
CC2D1A
coiled-coil and C2 domain containing 1A
chr9_+_90112117 0.40 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr1_-_219615984 0.40 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr6_+_158402860 0.40 ENST00000367122.2
ENST00000367121.3
ENST00000355585.4
ENST00000367113.4
SYNJ2
synaptojanin 2
chr1_+_26737253 0.39 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr11_-_124632179 0.38 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
ESAM
endothelial cell adhesion molecule
chr19_-_56109119 0.38 ENST00000587678.1
FIZ1
FLT3-interacting zinc finger 1
chr3_-_49722523 0.37 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr19_-_42721819 0.37 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
DEDD2
death effector domain containing 2
chr6_+_31783291 0.37 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A
heat shock 70kDa protein 1A
chr19_+_36347787 0.37 ENST00000347900.6
ENST00000360202.5
KIRREL2
kin of IRRE like 2 (Drosophila)
chr17_+_39405939 0.37 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr2_-_152590982 0.37 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
NEB
nebulin
chr16_+_2286726 0.36 ENST00000382437.4
ENST00000569184.1
DNASE1L2
deoxyribonuclease I-like 2
chr7_-_37488834 0.36 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr3_+_49027771 0.36 ENST00000475629.1
ENST00000444213.1
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr17_+_74732889 0.36 ENST00000591864.1
MFSD11
major facilitator superfamily domain containing 11
chr5_+_52856456 0.36 ENST00000296684.5
ENST00000506765.1
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr6_-_42016385 0.35 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr11_-_123525648 0.35 ENST00000527836.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr2_-_27603582 0.34 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr6_-_19804973 0.34 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr9_-_35619539 0.34 ENST00000396757.1
CD72
CD72 molecule
chr7_+_75028199 0.33 ENST00000437796.1
TRIM73
tripartite motif containing 73
chr10_-_128975273 0.33 ENST00000424811.2
FAM196A
family with sequence similarity 196, member A
chr7_+_12727250 0.32 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr2_+_220436917 0.32 ENST00000243786.2
INHA
inhibin, alpha
chr12_-_49333446 0.31 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr2_+_101437487 0.31 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr6_+_31795506 0.31 ENST00000375650.3
HSPA1B
heat shock 70kDa protein 1B
chr19_-_42916499 0.31 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr2_+_170590321 0.30 ENST00000392647.2
KLHL23
kelch-like family member 23
chr11_+_47279155 0.30 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr7_+_12726623 0.29 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr17_+_79495397 0.29 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr19_-_40324255 0.29 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr12_+_79258547 0.28 ENST00000457153.2
SYT1
synaptotagmin I
chr4_+_165675269 0.28 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr19_-_56056888 0.28 ENST00000592464.1
ENST00000420723.3
SBK3
SH3 domain binding kinase family, member 3
chr7_-_99698338 0.28 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr8_+_145438870 0.28 ENST00000527931.1
FAM203B
family with sequence similarity 203, member B
chr17_+_39411636 0.27 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr15_+_59730348 0.27 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr6_+_33172407 0.27 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr2_+_42104692 0.27 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr17_+_37793318 0.26 ENST00000336308.5
STARD3
StAR-related lipid transfer (START) domain containing 3
chr11_+_7618413 0.26 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr14_-_55369525 0.26 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1
GTP cyclohydrolase 1
chr16_+_83932684 0.26 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr15_-_45670717 0.26 ENST00000558163.1
ENST00000558336.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr11_+_22646739 0.25 ENST00000428556.2
AC103801.2
AC103801.2
chr16_-_103572 0.25 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr11_-_123525289 0.25 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr14_-_92413353 0.24 ENST00000556154.1
FBLN5
fibulin 5
chr3_-_178984759 0.24 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr17_-_56429500 0.24 ENST00000225504.3
SUPT4H1
suppressor of Ty 4 homolog 1 (S. cerevisiae)
chr12_+_50017327 0.24 ENST00000261897.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr17_-_7145106 0.24 ENST00000577035.1
GABARAP
GABA(A) receptor-associated protein
chr3_+_148545586 0.23 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr12_+_79258444 0.23 ENST00000261205.4
SYT1
synaptotagmin I
chr2_+_28113583 0.23 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr6_-_19804877 0.23 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr12_-_118406777 0.23 ENST00000339824.5
KSR2
kinase suppressor of ras 2
chr3_-_49851313 0.22 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr17_+_37793378 0.22 ENST00000544210.2
ENST00000581894.1
ENST00000394250.4
ENST00000579479.1
ENST00000577248.1
ENST00000580611.1
STARD3
StAR-related lipid transfer (START) domain containing 3
chrX_-_11445856 0.22 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr10_+_94608218 0.22 ENST00000371543.1
EXOC6
exocyst complex component 6
chr14_-_20923195 0.22 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr4_+_24661479 0.22 ENST00000569621.1
RP11-496D24.2
RP11-496D24.2
chr17_+_76164639 0.21 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
SYNGR2
synaptogyrin 2
chr8_-_123706338 0.21 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr2_-_43823093 0.21 ENST00000405006.4
THADA
thyroid adenoma associated
chr5_-_140053152 0.21 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr7_+_93535817 0.21 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr15_-_94614049 0.21 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr7_-_150675372 0.21 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_+_140103842 0.21 ENST00000495590.1
ENST00000275874.5
ENST00000537763.1
RAB19
RAB19, member RAS oncogene family
chr12_+_58176525 0.21 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr11_-_118972575 0.20 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr12_+_48357401 0.20 ENST00000429772.2
ENST00000449758.2
TMEM106C
transmembrane protein 106C
chr19_-_42573650 0.20 ENST00000593562.1
GRIK5
glutamate receptor, ionotropic, kainate 5
chr16_-_2314222 0.20 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr15_+_92937058 0.20 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr19_+_39881951 0.20 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr16_-_46865047 0.20 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr3_-_167191814 0.20 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr7_-_78400598 0.20 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_+_133710453 0.20 ENST00000318560.5
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr7_-_25702669 0.20 ENST00000446840.1
AC003090.1
AC003090.1
chr17_-_40833858 0.20 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chr1_-_11918988 0.20 ENST00000376468.3
NPPB
natriuretic peptide B
chr6_-_31938700 0.20 ENST00000495340.1
DXO
decapping exoribonuclease
chr3_-_50383096 0.20 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr17_-_48133054 0.20 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr15_+_45722727 0.19 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr8_-_144512576 0.19 ENST00000333480.2
MAFA
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
chr8_-_121824374 0.19 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr4_-_177190364 0.19 ENST00000296525.3
ASB5
ankyrin repeat and SOCS box containing 5
chr11_-_111749878 0.19 ENST00000260257.4
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr19_-_56048456 0.19 ENST00000413299.1
SBK2
SH3 domain binding kinase family, member 2
chr11_+_47279248 0.19 ENST00000449369.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr4_-_164534657 0.18 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr11_-_22647350 0.18 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr2_-_43823119 0.18 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA
thyroid adenoma associated
chr9_-_139258159 0.18 ENST00000371739.3
DNLZ
DNL-type zinc finger
chr11_-_62689046 0.18 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr17_-_29624343 0.18 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr2_-_179672142 0.18 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr4_+_165675197 0.18 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr2_-_28113217 0.18 ENST00000444339.2
RBKS
ribokinase
chr17_-_4458616 0.18 ENST00000381556.2
MYBBP1A
MYB binding protein (P160) 1a
chr3_-_128294929 0.18 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr6_-_130536774 0.17 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr15_+_92937144 0.17 ENST00000539113.1
ENST00000555434.1
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr12_-_13248598 0.17 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr5_-_94620239 0.17 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr7_-_37488777 0.17 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chr6_+_31939608 0.17 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr1_+_168250194 0.17 ENST00000367821.3
TBX19
T-box 19
chr1_-_31712401 0.17 ENST00000373736.2
NKAIN1
Na+/K+ transporting ATPase interacting 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FIGLA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.4 2.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 1.6 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3 2.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 0.9 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 0.7 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 1.0 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.2 0.8 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 0.7 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.2 0.5 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.2 0.9 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 0.7 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 0.6 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.7 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.7 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 2.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 1.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 1.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.0 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.4 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.5 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.4 GO:0003335 corneocyte development(GO:0003335)
0.1 0.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.2 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.1 0.5 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 1.3 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.6 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.0 GO:0030238 male sex determination(GO:0030238)
0.1 0.2 GO:0002879 leukocyte chemotaxis involved in inflammatory response(GO:0002232) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.2 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.3 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.1 2.2 GO:0002076 osteoblast development(GO:0002076)
0.1 0.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.7 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.5 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) regulation of muscle filament sliding(GO:0032971)
0.0 0.2 GO:1905040 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:2000981 auditory receptor cell fate determination(GO:0042668) negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.0 0.5 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.5 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0097104 postsynaptic membrane assembly(GO:0097104)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.6 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.9 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 2.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.8 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.0 1.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 1.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 1.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 1.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0030017 sarcomere(GO:0030017)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3 1.0 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.2 0.6 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.2 1.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 1.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 1.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.2 0.5 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.2 0.5 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 2.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.3 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 0.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 1.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.6 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.9 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.0 GO:0031545 peptidyl-proline dioxygenase activity(GO:0031543) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.0 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 2.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation