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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXA3_FOXC2

Z-value: 0.67

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol Gene ID Gene Info
FOXA3
ENSG00000170608.2 forkhead box A3
FOXC2
ENSG00000176692.4 forkhead box C2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA3hg19_v2_chr19_+_46367518_463675670.777.3e-05Click!
FOXC2hg19_v2_chr16_+_86600857_866009210.697.5e-04Click!

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_25616519 2.66 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr9_-_75567962 2.42 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_-_137674000 1.77 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr17_+_79953310 1.75 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr2_+_128175997 1.71 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr10_+_70847852 1.71 ENST00000242465.3
SRGN
serglycin
chr17_+_72426891 1.61 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_-_26695013 1.55 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr7_+_134832808 1.54 ENST00000275767.3
TMEM140
transmembrane protein 140
chr2_+_74120094 1.51 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2
actin, gamma 2, smooth muscle, enteric
chr11_-_102401469 1.45 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_-_165424973 1.44 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr4_-_174256276 1.43 ENST00000296503.5
HMGB2
high mobility group box 2
chrX_+_9431324 1.37 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr3_-_186080012 1.35 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr17_-_26694979 1.35 ENST00000438614.1
VTN
vitronectin
chr2_-_175711133 1.32 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr17_+_4613918 1.27 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2
arrestin, beta 2
chr10_-_118032979 1.22 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr21_-_43786634 1.17 ENST00000291527.2
TFF1
trefoil factor 1
chr10_-_118032697 1.12 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr11_+_8040739 1.06 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr5_+_156712372 1.06 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr17_-_26697304 1.06 ENST00000536498.1
VTN
vitronectin
chr11_+_65657875 1.05 ENST00000312579.2
CCDC85B
coiled-coil domain containing 85B
chr17_+_4613776 1.05 ENST00000269260.2
ARRB2
arrestin, beta 2
chr9_-_4299874 1.03 ENST00000381971.3
ENST00000477901.1
GLIS3
GLIS family zinc finger 3
chr5_+_169011033 1.00 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr11_-_115375107 1.00 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr7_+_106415457 0.92 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
RP5-884M6.1
chr2_+_46844290 0.91 ENST00000238892.3
CRIPT
cysteine-rich PDZ-binding protein
chr19_+_782755 0.91 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr4_-_164534657 0.89 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr17_-_57229155 0.89 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr11_+_34999328 0.88 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr17_-_46688334 0.88 ENST00000239165.7
HOXB7
homeobox B7
chr14_-_21562648 0.86 ENST00000555270.1
ZNF219
zinc finger protein 219
chr5_+_133859996 0.86 ENST00000512386.1
PHF15
jade family PHD finger 2
chr14_+_21156915 0.85 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr7_-_107968921 0.84 ENST00000442580.1
NRCAM
neuronal cell adhesion molecule
chr5_-_58571935 0.84 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_-_202579 0.82 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL
rabphilin 3A-like (without C2 domains)
chr1_+_200011711 0.82 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr8_-_145754428 0.75 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr14_-_94789663 0.73 ENST00000557225.1
ENST00000341584.3
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr19_+_54368001 0.72 ENST00000422045.1
AC008440.10
AC008440.10
chr10_+_95848824 0.71 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr1_-_149459549 0.71 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr1_-_246729544 0.71 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr17_-_26733604 0.71 ENST00000584426.1
ENST00000584995.1
SLC46A1
solute carrier family 46 (folate transporter), member 1
chr15_+_69857515 0.70 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chrX_-_15402498 0.70 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr2_-_192711968 0.69 ENST00000304141.4
SDPR
serum deprivation response
chr7_+_95115210 0.66 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr12_-_102591604 0.65 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr19_+_42806250 0.63 ENST00000598490.1
ENST00000341747.3
PRR19
proline rich 19
chr15_+_59910132 0.63 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_66820058 0.63 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr16_+_77233294 0.63 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr11_-_107582775 0.61 ENST00000305991.2
SLN
sarcolipin
chr18_+_3449330 0.61 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr16_-_67597789 0.59 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr17_+_72427477 0.59 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr16_+_84801852 0.58 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr1_+_18958008 0.58 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr16_+_20775358 0.58 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr17_-_26733179 0.57 ENST00000440501.1
ENST00000321666.5
SLC46A1
solute carrier family 46 (folate transporter), member 1
chr14_+_23299088 0.57 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr6_+_142623758 0.57 ENST00000541199.1
ENST00000435011.2
GPR126
G protein-coupled receptor 126
chrX_-_20236970 0.56 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_-_145275228 0.54 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr8_-_95449155 0.52 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr12_-_92539614 0.52 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr7_+_151791037 0.51 ENST00000419245.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr8_+_19171196 0.51 ENST00000518040.1
SH2D4A
SH2 domain containing 4A
chr10_-_46030841 0.50 ENST00000453424.2
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr2_+_169658928 0.50 ENST00000317647.7
ENST00000445023.2
NOSTRIN
nitric oxide synthase trafficking
chr5_-_59481406 0.49 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_169659121 0.48 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr4_+_15376165 0.48 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr2_-_175711978 0.48 ENST00000409089.2
CHN1
chimerin 1
chr17_-_39041479 0.47 ENST00000167588.3
KRT20
keratin 20
chr15_+_59665194 0.47 ENST00000560394.1
FAM81A
family with sequence similarity 81, member A
chr6_-_165989936 0.46 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr2_-_46844159 0.46 ENST00000474980.1
ENST00000306465.4
PIGF
phosphatidylinositol glycan anchor biosynthesis, class F
chr1_+_244214577 0.46 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr7_+_77469439 0.46 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr6_-_42016385 0.45 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr18_+_68002675 0.45 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr17_-_79212825 0.45 ENST00000374769.2
ENTHD2
ENTH domain containing 2
chr3_+_119316721 0.45 ENST00000488919.1
ENST00000495992.1
PLA1A
phospholipase A1 member A
chr3_+_148447887 0.45 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr14_+_38065052 0.45 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr15_+_59664884 0.44 ENST00000558348.1
FAM81A
family with sequence similarity 81, member A
chr7_+_112063192 0.44 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr5_+_142286887 0.43 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr4_-_103266626 0.43 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr10_+_35484053 0.43 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM
cAMP responsive element modulator
chr17_-_19290483 0.42 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr8_+_101349823 0.42 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr14_+_74034310 0.42 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr5_+_60933634 0.42 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr7_-_107443652 0.42 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr3_+_119316689 0.42 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr3_+_50712672 0.42 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chrX_-_20237059 0.41 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr17_-_79212884 0.41 ENST00000300714.3
ENTHD2
ENTH domain containing 2
chr15_-_59041954 0.41 ENST00000439637.1
ENST00000558004.1
ADAM10
ADAM metallopeptidase domain 10
chr14_-_23299009 0.40 ENST00000488800.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_31926623 0.39 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr7_-_81635106 0.39 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr12_-_15865844 0.39 ENST00000543612.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr7_+_151791074 0.39 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr14_+_56585048 0.38 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr4_-_170679024 0.37 ENST00000393381.2
C4orf27
chromosome 4 open reading frame 27
chr12_+_72080253 0.36 ENST00000549735.1
TMEM19
transmembrane protein 19
chr9_+_67977438 0.36 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr10_-_74283694 0.36 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
MICU1
mitochondrial calcium uptake 1
chr2_+_196521845 0.36 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr10_-_31288398 0.36 ENST00000538351.2
ZNF438
zinc finger protein 438
chr14_+_56584414 0.36 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr1_-_54405773 0.36 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr14_-_31926701 0.35 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr8_-_80993010 0.35 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr5_+_140529630 0.35 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr15_-_59665062 0.35 ENST00000288235.4
MYO1E
myosin IE
chr14_-_101036119 0.35 ENST00000355173.2
BEGAIN
brain-enriched guanylate kinase-associated
chr17_-_27038063 0.35 ENST00000439862.3
PROCA1
protein interacting with cyclin A1
chr8_-_23261589 0.34 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2
lysyl oxidase-like 2
chr8_+_19171128 0.34 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr14_+_56127989 0.34 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr14_+_58711539 0.34 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr2_+_196522032 0.34 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_-_46844242 0.34 ENST00000281382.6
PIGF
phosphatidylinositol glycan anchor biosynthesis, class F
chrX_+_135730373 0.33 ENST00000370628.2
CD40LG
CD40 ligand
chr2_+_162165038 0.33 ENST00000437630.1
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr15_+_80364901 0.33 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chrX_+_135730297 0.33 ENST00000370629.2
CD40LG
CD40 ligand
chr3_+_69985734 0.33 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr14_+_20215587 0.32 ENST00000331723.1
OR4Q3
olfactory receptor, family 4, subfamily Q, member 3
chr19_+_50380917 0.32 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr5_+_61874562 0.32 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr4_+_76871883 0.32 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr2_-_145275828 0.32 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr12_-_106480587 0.31 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr3_+_141106643 0.31 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr19_+_50380682 0.30 ENST00000221543.5
TBC1D17
TBC1 domain family, member 17
chr3_+_148545586 0.30 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr6_+_10528560 0.30 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chrX_+_10124977 0.30 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr20_+_11898507 0.30 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr1_-_201096312 0.30 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr15_-_50411412 0.29 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr3_-_45957534 0.29 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr12_+_94071129 0.29 ENST00000552983.1
ENST00000332896.3
ENST00000552033.1
ENST00000548483.1
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr8_+_104384616 0.29 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr3_+_158991025 0.29 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr17_+_79213039 0.29 ENST00000431388.2
C17orf89
chromosome 17 open reading frame 89
chr9_-_28670283 0.28 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr4_+_57138437 0.28 ENST00000504228.1
ENST00000541073.1
KIAA1211
KIAA1211
chr9_+_129097520 0.28 ENST00000436593.3
MVB12B
multivesicular body subunit 12B
chr3_-_45957088 0.27 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr12_+_94071341 0.27 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr17_-_77967433 0.27 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr13_-_36429763 0.27 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr2_-_86422523 0.27 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT
inner membrane protein, mitochondrial
chr3_+_142315225 0.26 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr15_+_49462434 0.26 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
GALK2
galactokinase 2
chr7_+_26438187 0.26 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
AC004540.5
chr12_-_57328187 0.26 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr15_+_75335604 0.25 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr19_-_51141196 0.25 ENST00000338916.4
SYT3
synaptotagmin III
chr8_-_30002179 0.25 ENST00000320542.3
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr14_-_23526739 0.25 ENST00000397359.3
ENST00000487137.2
CDH24
cadherin 24, type 2
chr4_-_140223670 0.24 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr2_+_196521903 0.24 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr1_-_167522982 0.24 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr3_+_137728842 0.24 ENST00000183605.5
CLDN18
claudin 18
chr17_+_7487146 0.24 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr5_+_161494770 0.24 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr7_-_107643567 0.24 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr14_+_74551650 0.24 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr14_+_56127960 0.24 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr7_-_121944491 0.23 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr15_-_66797172 0.23 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4
ribosomal protein L4
chr12_-_71551652 0.23 ENST00000546561.1
TSPAN8
tetraspanin 8
chr5_+_161495038 0.23 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr7_-_107643674 0.22 ENST00000222399.6
LAMB1
laminin, beta 1
chr22_-_39268308 0.22 ENST00000407418.3
CBX6
chromobox homolog 6
chr6_-_41715128 0.22 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC
progastricsin (pepsinogen C)
chr2_+_136343904 0.22 ENST00000436436.1
R3HDM1
R3H domain containing 1
chr7_+_106505696 0.21 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr1_-_43855479 0.21 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr15_+_71185148 0.21 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr15_+_69854027 0.21 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr1_+_207277590 0.21 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr7_+_106505912 0.21 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr1_+_84609944 0.21 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_122018346 0.21 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr3_-_107941230 0.21 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 2.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.4 1.7 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.4 2.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.4 3.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.3 1.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.5 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.3 GO:0051958 methotrexate transport(GO:0051958)
0.2 0.6 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.2 0.9 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.2 0.6 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 0.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 1.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 1.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 2.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.6 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 1.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.0 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.8 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 2.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 1.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0018277 protein deamination(GO:0018277)
0.1 1.0 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.7 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 1.4 GO:0044849 estrous cycle(GO:0044849)
0.1 0.5 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.2 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.8 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.4 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.0 0.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0039023 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.0 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.0 0.3 GO:0019075 virus maturation(GO:0019075)
0.0 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.9 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.4 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 1.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.4 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.6 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.2 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.2 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.4 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.8 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.7 GO:0051023 regulation of immunoglobulin secretion(GO:0051023)
0.0 0.7 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.7 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.2 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.5 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 1.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 1.0 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.3 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0046218 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 0.5 GO:0043257 laminin-8 complex(GO:0043257)
0.1 0.9 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 2.7 GO:0005916 fascia adherens(GO:0005916) catenin complex(GO:0016342)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.9 GO:0042588 zymogen granule(GO:0042588)
0.1 0.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 1.5 GO:0032982 myosin filament(GO:0032982)
0.1 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.3 1.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.3 2.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 2.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 0.7 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.2 0.7 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 1.3 GO:0015350 methotrexate transporter activity(GO:0015350)
0.2 0.6 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 0.8 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.9 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.9 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.9 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 2.7 GO:0045294 alpha-catenin binding(GO:0045294) gamma-catenin binding(GO:0045295)
0.1 1.0 GO:0043515 kinetochore binding(GO:0043515)
0.1 2.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.2 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1 0.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 3.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.9 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.8 PID ATM PATHWAY ATM pathway
0.0 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 2.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 2.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine