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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXJ2

Z-value: 1.25

Motif logo

Transcription factors associated with FOXJ2

Gene Symbol Gene ID Gene Info
ENSG00000065970.4 forkhead box J2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXJ2hg19_v2_chr12_+_8185288_81853390.732.5e-04Click!

Activity profile of FOXJ2 motif

Sorted Z-values of FOXJ2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_56989485 5.28 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667 antisense RNA 1 (head to head)
chr6_-_56507586 4.50 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
dystonin
chr4_-_90757364 4.23 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_90756769 4.19 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chrX_+_99899180 3.74 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr13_-_38172863 3.74 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr1_+_107599267 3.59 ENST00000361318.5
ENST00000370078.1
protein arginine methyltransferase 6
chr7_+_73242069 3.26 ENST00000435050.1
claudin 4
chr4_-_68749745 3.15 ENST00000283916.6
transmembrane protease, serine 11D
chr10_-_25010795 3.03 ENST00000416305.1
ENST00000376410.2
Rho GTPase activating protein 21
chr4_-_68749699 2.83 ENST00000545541.1
transmembrane protease, serine 11D
chr20_-_45530365 2.67 ENST00000414085.1
RP11-323C15.2
chr14_+_37126765 2.56 ENST00000402703.2
paired box 9
chr12_-_8815404 2.52 ENST00000359478.2
ENST00000396549.2
microfibrillar associated protein 5
chr3_+_128444994 2.40 ENST00000482525.1
RAB7A, member RAS oncogene family
chr1_-_230513367 2.33 ENST00000321327.2
ENST00000525115.1
piggyBac transposable element derived 5
chr12_-_8815215 2.32 ENST00000544889.1
ENST00000543369.1
microfibrillar associated protein 5
chr1_-_60392452 2.31 ENST00000371204.3
cytochrome P450, family 2, subfamily J, polypeptide 2
chr11_+_35201826 2.21 ENST00000531873.1
CD44 molecule (Indian blood group)
chr10_+_28822417 2.18 ENST00000428935.1
ENST00000420266.1
WW domain containing adaptor with coiled-coil
chr21_-_27423339 2.12 ENST00000415997.1
amyloid beta (A4) precursor protein
chr17_+_66511540 2.11 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chrX_-_30877837 2.10 ENST00000378930.3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr14_-_36990354 2.05 ENST00000518149.1
NK2 homeobox 1
chr12_-_8815477 2.03 ENST00000433590.2
microfibrillar associated protein 5
chr12_-_8815299 2.03 ENST00000535336.1
microfibrillar associated protein 5
chr7_-_80548493 2.01 ENST00000536800.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_+_210518057 2.00 ENST00000452717.1
microtubule-associated protein 2
chr7_-_80548667 1.93 ENST00000265361.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_-_26124138 1.90 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr20_+_12989822 1.88 ENST00000378194.4
serine palmitoyltransferase, long chain base subunit 3
chr2_+_210517895 1.85 ENST00000447185.1
microtubule-associated protein 2
chr2_+_120770686 1.84 ENST00000331393.4
ENST00000443124.1
erythrocyte membrane protein band 4.1 like 5
chr3_+_128444965 1.83 ENST00000265062.3
RAB7A, member RAS oncogene family
chr17_+_66511224 1.76 ENST00000588178.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr19_+_7580103 1.73 ENST00000596712.1
zinc finger protein 358
chr19_+_56989609 1.69 ENST00000601875.1
ZNF667 antisense RNA 1 (head to head)
chr8_+_125860939 1.60 ENST00000525292.1
ENST00000528090.1
long intergenic non-protein coding RNA 964
chr11_+_58938903 1.60 ENST00000532982.1
deltex homolog 4 (Drosophila)
chr4_+_57774042 1.60 ENST00000309042.7
RE1-silencing transcription factor
chr3_+_160822462 1.59 ENST00000468606.1
ENST00000460503.1
NMD3 ribosome export adaptor
chr18_-_21852143 1.59 ENST00000399443.3
oxysterol binding protein-like 1A
chr10_+_28822636 1.55 ENST00000442148.1
ENST00000448193.1
WW domain containing adaptor with coiled-coil
chr1_+_43855545 1.52 ENST00000372450.4
ENST00000310739.4
seizure threshold 2 homolog (mouse)
chr4_-_140544386 1.48 ENST00000561977.1
RP11-308D13.3
chr1_+_223889310 1.45 ENST00000434648.1
calpain 2, (m/II) large subunit
chr19_+_2819943 1.44 ENST00000591265.1
zinc finger protein 554
chr1_+_117963209 1.44 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr9_-_71869642 1.42 ENST00000600472.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr19_+_13134772 1.38 ENST00000587760.1
ENST00000585575.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr10_+_28822236 1.33 ENST00000347934.4
ENST00000354911.4
WW domain containing adaptor with coiled-coil
chr3_+_122103014 1.30 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
family with sequence similarity 162, member A
chr2_+_162016804 1.30 ENST00000392749.2
ENST00000440506.1
TRAF family member-associated NFKB activator
chr15_+_42697065 1.29 ENST00000565559.1
calpain 3, (p94)
chr1_-_220263096 1.29 ENST00000463953.1
ENST00000354807.3
ENST00000414869.2
ENST00000498237.2
ENST00000498791.2
ENST00000544404.1
ENST00000480959.2
ENST00000322067.7
3'(2'), 5'-bisphosphate nucleotidase 1
chr4_+_26344754 1.28 ENST00000515573.1
recombination signal binding protein for immunoglobulin kappa J region
chr1_+_36335351 1.27 ENST00000373206.1
argonaute RISC catalytic component 1
chr6_+_30539153 1.25 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ATP-binding cassette, sub-family F (GCN20), member 1
chr4_-_99851766 1.23 ENST00000450253.2
eukaryotic translation initiation factor 4E
chr2_-_85641162 1.23 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr12_+_123949053 1.21 ENST00000350887.5
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr20_+_12989895 1.21 ENST00000450297.1
serine palmitoyltransferase, long chain base subunit 3
chr3_+_132036243 1.17 ENST00000475741.1
ENST00000351273.7
acid phosphatase, prostate
chr3_+_171757346 1.14 ENST00000421757.1
ENST00000415807.2
ENST00000392699.1
fibronectin type III domain containing 3B
chr2_+_162016827 1.13 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr20_-_34638841 1.13 ENST00000565493.1
long intergenic non-protein coding RNA 657
chr21_-_35899113 1.12 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr22_+_24407642 1.12 ENST00000454754.1
ENST00000263119.5
calcineurin binding protein 1
chr9_+_131684027 1.11 ENST00000426694.1
phytanoyl-CoA dioxygenase domain containing 1
chr19_+_2819854 1.11 ENST00000317243.5
zinc finger protein 554
chrX_+_22056165 1.07 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr15_-_34628951 1.07 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr14_+_90863364 1.06 ENST00000447653.3
ENST00000553542.1
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_145883868 1.05 ENST00000447947.2
G protein-coupled receptor 89C
chr4_+_28437071 1.03 ENST00000509416.1
RP11-123O22.1
chr15_+_42697018 1.02 ENST00000397204.4
calpain 3, (p94)
chr3_-_49131614 1.01 ENST00000450685.1
glutamine-rich 1
chr6_+_26124373 1.00 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr7_+_132937820 0.99 ENST00000393161.2
ENST00000253861.4
exocyst complex component 4
chr4_-_47983519 0.99 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr14_-_94547541 0.96 ENST00000544005.1
ENST00000555054.1
ENST00000330836.5
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr15_+_42696992 0.93 ENST00000561817.1
calpain 3, (p94)
chr11_-_57089671 0.90 ENST00000532437.1
tankyrase 1 binding protein 1, 182kDa
chr1_-_38019878 0.88 ENST00000296215.6
Smad nuclear interacting protein 1
chr12_-_112546547 0.87 ENST00000547133.1
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr5_+_36606992 0.87 ENST00000505202.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_49131788 0.86 ENST00000395443.2
ENST00000411682.1
glutamine-rich 1
chr17_+_37617721 0.86 ENST00000584632.1
cyclin-dependent kinase 12
chr11_+_120081475 0.84 ENST00000328965.4
OAF homolog (Drosophila)
chr9_+_110046334 0.84 ENST00000416373.2
RAD23 homolog B (S. cerevisiae)
chr9_-_136006496 0.83 ENST00000372062.3
ral guanine nucleotide dissociation stimulator
chr6_+_76599809 0.82 ENST00000430435.1
myosin VI
chrX_+_107683096 0.80 ENST00000328300.6
ENST00000361603.2
collagen, type IV, alpha 5
chr1_+_43855560 0.79 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr1_-_156269428 0.77 ENST00000339922.3
von Hippel-Lindau tumor suppressor-like
chr1_-_179846928 0.76 ENST00000367612.3
ENST00000609928.1
torsin A interacting protein 2
chr2_+_231921574 0.76 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chrX_-_107682702 0.74 ENST00000372216.4
collagen, type IV, alpha 6
chr7_-_33140498 0.73 ENST00000448915.1
retinitis pigmentosa 9 (autosomal dominant)
chr20_+_56964169 0.72 ENST00000475243.1
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr13_-_46716969 0.71 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_53469525 0.70 ENST00000544405.2
retinoblastoma-like 2 (p130)
chr17_-_56494908 0.70 ENST00000577716.1
ring finger protein 43
chr6_-_130543958 0.70 ENST00000437477.2
ENST00000439090.2
sterile alpha motif domain containing 3
chr2_+_157330081 0.69 ENST00000409674.1
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr12_+_27396901 0.68 ENST00000541191.1
ENST00000389032.3
serine/threonine kinase 38 like
chr2_+_162016916 0.68 ENST00000405852.1
TRAF family member-associated NFKB activator
chr19_+_57752200 0.68 ENST00000414468.2
zinc finger protein 805
chr19_-_49865639 0.68 ENST00000593945.1
ENST00000601519.1
ENST00000539846.1
ENST00000596757.1
ENST00000311227.2
TEA domain family member 2
chrX_+_55744228 0.67 ENST00000262850.7
Ras-related GTP binding B
chr8_+_104383759 0.66 ENST00000415886.2
collagen triple helix repeat containing 1
chr3_+_57875738 0.66 ENST00000417128.1
ENST00000438794.1
sarcolemma associated protein
chr20_+_55926566 0.66 ENST00000411894.1
ENST00000429339.1
ribonucleic acid export 1
chr17_+_17685422 0.66 ENST00000395774.1
retinoic acid induced 1
chr17_-_56494882 0.65 ENST00000584437.1
ring finger protein 43
chr17_+_25958174 0.65 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr9_+_5510558 0.64 ENST00000397747.3
programmed cell death 1 ligand 2
chr12_-_96429423 0.63 ENST00000228740.2
leukotriene A4 hydrolase
chr3_+_57875711 0.63 ENST00000442599.2
sarcolemma associated protein
chr19_-_14196574 0.61 ENST00000548523.1
ENST00000343945.5
chromosome 19 open reading frame 67
chr14_+_52456327 0.60 ENST00000556760.1
chromosome 14 open reading frame 166
chr18_-_3013307 0.60 ENST00000584294.1
lipin 2
chr4_+_57845024 0.58 ENST00000431623.2
ENST00000441246.2
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chrX_+_55744166 0.57 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr19_+_57751973 0.56 ENST00000535550.1
zinc finger protein 805
chr3_-_100551141 0.55 ENST00000478235.1
ENST00000471901.1
ABI family, member 3 (NESH) binding protein
chr19_+_57752022 0.54 ENST00000354309.4
zinc finger protein 805
chr21_-_27945562 0.53 ENST00000299340.4
ENST00000435845.2
cysteine/tyrosine-rich 1
chr17_-_56494713 0.53 ENST00000407977.2
ring finger protein 43
chr1_-_165667545 0.52 ENST00000538148.1
aldehyde dehydrogenase 9 family, member A1
chr1_-_217804377 0.52 ENST00000366935.3
ENST00000366934.3
G patch domain containing 2
chr15_+_64428529 0.51 ENST00000560861.1
sorting nexin 1
chr11_-_5537920 0.49 ENST00000380184.1
ubiquilin-like
chr1_-_94079648 0.49 ENST00000370247.3
breast cancer anti-estrogen resistance 3
chr11_+_64085560 0.49 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
peroxiredoxin 5
chr4_+_128554081 0.47 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr18_+_44812072 0.45 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
chr9_+_5890802 0.44 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
melan-A
chr6_+_33422343 0.44 ENST00000395064.2
zinc finger and BTB domain containing 9
chr11_-_57089774 0.44 ENST00000527207.1
tankyrase 1 binding protein 1, 182kDa
chr21_-_27945464 0.42 ENST00000400043.3
cysteine/tyrosine-rich 1
chr14_+_22591276 0.40 ENST00000390455.3
T cell receptor alpha variable 26-1
chr9_+_5510492 0.39 ENST00000397745.2
programmed cell death 1 ligand 2
chr8_-_10336885 0.39 ENST00000520494.1
RP11-981G7.3
chr1_+_22778337 0.38 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr14_+_52456193 0.37 ENST00000261700.3
chromosome 14 open reading frame 166
chr4_+_89299994 0.36 ENST00000264346.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr6_+_31462658 0.36 ENST00000538442.1
MHC class I polypeptide-related sequence B
chr12_+_56495115 0.35 ENST00000548861.1
Uncharacterized protein
chr9_-_98268883 0.35 ENST00000551630.1
ENST00000548420.1
patched 1
chr10_+_50887683 0.35 ENST00000374113.3
ENST00000374111.3
ENST00000374112.3
ENST00000535836.1
chromosome 10 open reading frame 53
chr1_+_114472992 0.34 ENST00000514621.1
homeodomain interacting protein kinase 1
chr3_+_132036207 0.34 ENST00000336375.5
ENST00000495911.1
acid phosphatase, prostate
chr12_-_57941004 0.33 ENST00000550750.1
ENST00000548249.1
dynactin 2 (p50)
chr2_+_120770645 0.31 ENST00000443902.2
erythrocyte membrane protein band 4.1 like 5
chr4_+_89299885 0.31 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_-_64009658 0.31 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr13_-_96329048 0.30 ENST00000606011.1
ENST00000499499.2
DNAJC3 antisense RNA 1 (head to head)
chr18_+_32455201 0.29 ENST00000590831.2
dystrobrevin, alpha
chr7_+_95171457 0.29 ENST00000601424.1
Protein LOC100996577
chr19_-_55874611 0.28 ENST00000424985.3
family with sequence similarity 71, member E2
chr5_-_110062349 0.28 ENST00000511883.2
ENST00000455884.2
transmembrane protein 232
chr15_-_96590126 0.28 ENST00000561051.1
RP11-4G2.1
chr5_-_110062384 0.26 ENST00000429839.2
transmembrane protein 232
chr22_+_46449674 0.26 ENST00000381051.2
hsa-mir-4763
chr9_+_4662282 0.25 ENST00000381883.2
phosphatidic acid phosphatase type 2 domain containing 2
chr6_-_99842041 0.24 ENST00000254759.3
ENST00000369242.1
coenzyme Q3 methyltransferase
chr2_-_39414848 0.24 ENST00000451199.1
cyclin-dependent kinase-like 4
chr6_-_43021437 0.24 ENST00000265348.3
cullin 7
chr1_+_223889285 0.23 ENST00000433674.2
calpain 2, (m/II) large subunit
chr7_+_23637763 0.23 ENST00000410069.1
coiled-coil domain containing 126
chr1_-_72566613 0.23 ENST00000306821.3
neuronal growth regulator 1
chr19_-_9226439 0.23 ENST00000293614.1
ENST00000541538.1
olfactory receptor, family 7, subfamily G, member 1
chr8_-_54755789 0.23 ENST00000359530.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr3_-_64009102 0.21 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr7_-_112726393 0.21 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
G protein-coupled receptor 85
chr1_+_146373546 0.21 ENST00000446760.2
neuroblastoma breakpoint family, member 12
chr5_+_179135246 0.20 ENST00000508787.1
calnexin
chr11_+_63137251 0.20 ENST00000310969.4
ENST00000279178.3
solute carrier family 22 (organic anion transporter), member 9
chr6_-_43021612 0.19 ENST00000535468.1
cullin 7
chr15_+_67430339 0.19 ENST00000439724.3
SMAD family member 3
chr1_-_27952617 0.19 ENST00000457296.1
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr10_-_105992059 0.19 ENST00000369720.1
ENST00000369719.1
ENST00000357060.3
ENST00000428666.1
ENST00000278064.2
WD repeat domain 96
chr2_-_206950781 0.18 ENST00000403263.1
INO80 complex subunit D
chr7_-_115608304 0.18 ENST00000457268.1
transcription factor EC
chr6_-_121655552 0.17 ENST00000275159.6
TBC1 domain family, member 32
chr8_+_134029937 0.17 ENST00000518108.1
thyroglobulin
chr12_+_108523133 0.17 ENST00000547525.1
WSC domain containing 2
chr5_+_36606700 0.17 ENST00000416645.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_19811132 0.17 ENST00000433834.1
capping protein (actin filament) muscle Z-line, beta
chr1_+_28879588 0.17 ENST00000373830.3
tRNA selenocysteine 1 associated protein 1
chr17_+_39346139 0.17 ENST00000398470.1
ENST00000318329.5
keratin associated protein 9-1
chr20_+_55926625 0.16 ENST00000452119.1
ribonucleic acid export 1
chr8_+_103991013 0.16 ENST00000517983.1
KB-1507C5.4
chr3_+_48413709 0.15 ENST00000296438.5
ENST00000436231.1
ENST00000445170.1
ENST00000415155.1
F-box and WD repeat domain containing 12
chr19_+_35899569 0.15 ENST00000600405.1
AC002511.1
chrX_+_8432871 0.14 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
variable charge, X-linked 3B
chr1_+_244624678 0.13 ENST00000366534.4
ENST00000366533.4
ENST00000428042.1
ENST00000366531.3
chromosome 1 open reading frame 101
chr16_+_2106134 0.13 ENST00000467949.1
tuberous sclerosis 2
chr8_+_101170257 0.13 ENST00000251809.3
sperm associated antigen 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.4 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
1.3 5.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
1.2 3.6 GO:0034970 histone H3-R2 methylation(GO:0034970)
1.1 4.2 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.6 3.7 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.5 1.6 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.5 3.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.4 3.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.4 2.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.4 3.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 1.5 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.4 1.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 3.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 2.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.3 5.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 4.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 1.6 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.2 2.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.2 1.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 1.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 1.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.2 3.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 1.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.2 9.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 2.1 GO:0021759 globus pallidus development(GO:0021759)
0.2 1.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.3 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 3.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.7 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 1.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 2.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.0 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.7 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 3.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.7 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.4 GO:0010157 response to chlorate(GO:0010157)
0.1 2.6 GO:0060325 face morphogenesis(GO:0060325)
0.1 6.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 1.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 0.7 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.6 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 1.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.9 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 1.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.7 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 3.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 1.3 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 1.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 3.9 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.6 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 1.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 1.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.8 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.1 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 1.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.5 GO:0031673 H zone(GO:0031673)
0.5 3.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 4.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.3 8.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.3 2.3 GO:1990130 Iml1 complex(GO:1990130)
0.3 0.9 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.3 2.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 0.8 GO:0034515 proteasome storage granule(GO:0034515)
0.2 1.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 3.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 2.1 GO:1990812 growth cone filopodium(GO:1990812)
0.2 8.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 0.8 GO:0071942 XPC complex(GO:0071942)
0.1 3.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.8 GO:0098862 brush border(GO:0005903) cluster of actin-based cell projections(GO:0098862)
0.1 2.5 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.8 GO:0030891 VCB complex(GO:0030891)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.2 GO:0000243 commitment complex(GO:0000243)
0.1 3.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.9 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 1.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.9 GO:0000786 nucleosome(GO:0000786)
0.0 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.8 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 3.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.9 3.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.4 1.3 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.4 3.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 3.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.4 1.5 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.3 0.8 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.2 0.7 GO:0033149 FFAT motif binding(GO:0033149)
0.2 7.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 3.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.7 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 0.6 GO:0048030 disaccharide binding(GO:0048030)
0.2 3.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 2.1 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 3.2 GO:0055103 ligase regulator activity(GO:0055103)
0.1 1.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 3.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.1 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 2.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 10.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 2.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.0 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.3 GO:0000150 recombinase activity(GO:0000150)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119)
0.0 0.5 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 3.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 5.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 3.7 GO:0019838 growth factor binding(GO:0019838)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 10.2 PID NOTCH PATHWAY Notch signaling pathway
0.1 4.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 2.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 4.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 8.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.0 PID INSULIN PATHWAY Insulin Pathway
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 11.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 3.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 4.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein