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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXO4

Z-value: 0.72

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Transcription factors associated with FOXO4

Gene Symbol Gene ID Gene Info
FOXO4
ENSG00000184481.12 forkhead box O4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO4hg19_v2_chrX_+_70316005_70316047-0.632.6e-03Click!

Activity profile of FOXO4 motif

Sorted Z-values of FOXO4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_70847852 2.59 ENST00000242465.3
SRGN
serglycin
chr8_+_31497271 2.27 ENST00000520407.1
NRG1
neuregulin 1
chr5_-_137674000 2.15 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr7_+_37723420 2.02 ENST00000476620.1
EPDR1
ependymin related 1
chr6_+_62284008 1.77 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr1_+_200011711 1.68 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr7_+_134832808 1.47 ENST00000275767.3
TMEM140
transmembrane protein 140
chr1_+_66796401 1.47 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_-_102591604 1.44 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr6_-_127780510 1.38 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr17_-_46806540 1.34 ENST00000290295.7
HOXB13
homeobox B13
chr5_-_59481406 1.29 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_-_86432547 1.29 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr17_+_67410832 1.23 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr7_-_95225768 1.14 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr1_-_57045228 1.13 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr4_-_139163491 1.12 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr4_-_155511887 1.10 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr11_+_123301012 1.07 ENST00000533341.1
AP000783.1
Uncharacterized protein
chr12_+_54378923 1.04 ENST00000303460.4
HOXC10
homeobox C10
chr5_-_58571935 1.02 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_+_9431324 0.99 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr8_-_40755333 0.96 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr11_+_844067 0.95 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr19_+_859654 0.94 ENST00000592860.1
CFD
complement factor D (adipsin)
chr21_+_37507210 0.93 ENST00000290354.5
CBR3
carbonyl reductase 3
chr11_+_844406 0.89 ENST00000397404.1
TSPAN4
tetraspanin 4
chr17_+_72426891 0.89 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chrX_-_20236970 0.87 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_+_173955327 0.87 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr6_-_152623231 0.87 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr6_-_152489484 0.85 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr15_+_59397275 0.85 ENST00000288207.2
CCNB2
cyclin B2
chr22_-_43398442 0.83 ENST00000422336.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr12_+_121416489 0.82 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr2_-_100925967 0.81 ENST00000409647.1
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr7_+_7811992 0.81 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr17_-_1418972 0.81 ENST00000571274.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr2_+_196521903 0.81 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_+_196521845 0.79 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr5_+_133859996 0.78 ENST00000512386.1
PHF15
jade family PHD finger 2
chr1_-_47655686 0.77 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr14_+_102276132 0.76 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr16_+_77233294 0.76 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr17_+_72427477 0.75 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_-_65150103 0.75 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr16_+_84801852 0.75 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr7_-_95064264 0.74 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2
paraoxonase 2
chr12_+_121416340 0.73 ENST00000257555.6
ENST00000400024.2
HNF1A
HNF1 homeobox A
chr3_+_101504200 0.73 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr12_+_53491220 0.73 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr8_-_62602327 0.72 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr8_+_19171196 0.71 ENST00000518040.1
SH2D4A
SH2 domain containing 4A
chr2_+_196522032 0.71 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr10_-_13570533 0.70 ENST00000396900.2
ENST00000396898.2
BEND7
BEN domain containing 7
chr8_-_145754428 0.70 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr8_-_101348408 0.70 ENST00000519527.1
ENST00000522369.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr1_+_153940346 0.69 ENST00000405694.3
ENST00000449724.1
ENST00000368607.3
ENST00000271889.4
CREB3L4
cAMP responsive element binding protein 3-like 4
chr10_-_25241499 0.69 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr7_+_12250943 0.68 ENST00000442107.1
TMEM106B
transmembrane protein 106B
chr16_-_4323015 0.66 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr6_-_105627735 0.66 ENST00000254765.3
POPDC3
popeye domain containing 3
chr1_+_41448820 0.65 ENST00000372616.1
CTPS1
CTP synthase 1
chr5_-_59064458 0.65 ENST00000502575.1
ENST00000507116.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_192711968 0.64 ENST00000304141.4
SDPR
serum deprivation response
chr2_-_165424973 0.63 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr7_+_77469439 0.61 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr6_-_42016385 0.61 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr9_-_15472730 0.61 ENST00000481862.1
PSIP1
PC4 and SFRS1 interacting protein 1
chr3_-_185826718 0.61 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr22_+_45809560 0.61 ENST00000342894.3
ENST00000538017.1
RIBC2
RIB43A domain with coiled-coils 2
chr2_-_148779106 0.60 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr12_+_121416437 0.60 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A
HNF1 homeobox A
chr3_-_129375556 0.59 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr19_+_859425 0.59 ENST00000327726.6
CFD
complement factor D (adipsin)
chr5_+_156712372 0.58 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr12_+_54378849 0.58 ENST00000515593.1
HOXC10
homeobox C10
chr2_+_58134756 0.57 ENST00000435505.2
ENST00000417641.2
VRK2
vaccinia related kinase 2
chr9_-_39288092 0.57 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3
contactin associated protein-like 3
chr3_-_134092561 0.57 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr2_+_109204909 0.55 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_162165038 0.54 ENST00000437630.1
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr1_+_153940713 0.53 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4
cAMP responsive element binding protein 3-like 4
chr4_+_78804393 0.53 ENST00000502384.1
MRPL1
mitochondrial ribosomal protein L1
chr2_+_109204743 0.53 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr14_-_75518129 0.52 ENST00000556257.1
ENST00000557648.1
ENST00000553263.1
ENST00000355774.2
ENST00000380968.2
ENST00000238662.7
MLH3
mutL homolog 3
chr1_+_153940741 0.52 ENST00000431292.1
CREB3L4
cAMP responsive element binding protein 3-like 4
chr11_+_34999328 0.52 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr14_+_23067166 0.52 ENST00000216327.6
ENST00000542041.1
ABHD4
abhydrolase domain containing 4
chr19_-_36523529 0.52 ENST00000593074.1
CLIP3
CAP-GLY domain containing linker protein 3
chr1_+_10490127 0.52 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
APITD1
APITD1-CORT
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr1_-_241803649 0.50 ENST00000366554.2
OPN3
opsin 3
chr3_-_28389922 0.49 ENST00000415852.1
AZI2
5-azacytidine induced 2
chr9_+_67977438 0.49 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr1_-_153514241 0.48 ENST00000368718.1
ENST00000359215.1
S100A5
S100 calcium binding protein A5
chr12_+_118454500 0.48 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
RFC5
replication factor C (activator 1) 5, 36.5kDa
chr9_+_108006880 0.47 ENST00000374723.1
ENST00000374720.3
ENST00000374724.1
SLC44A1
solute carrier family 44 (choline transporter), member 1
chr1_-_54405773 0.47 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr1_+_81106951 0.47 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr2_-_101767715 0.47 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr5_+_140529630 0.46 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr10_-_118032979 0.46 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr2_+_233527443 0.46 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chrX_+_120181457 0.44 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr12_+_6881678 0.44 ENST00000441671.2
ENST00000203629.2
LAG3
lymphocyte-activation gene 3
chr14_+_56127989 0.43 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr17_-_15554940 0.43 ENST00000455584.2
RP11-385D13.1
Uncharacterized protein
chr1_-_43855479 0.43 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr8_+_19171128 0.42 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr3_+_148447887 0.42 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr4_-_164534657 0.42 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr3_-_28390415 0.41 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr16_-_18887627 0.40 ENST00000563235.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr14_+_50234827 0.40 ENST00000554589.1
ENST00000557247.1
KLHDC2
kelch domain containing 2
chr19_-_29704448 0.40 ENST00000304863.4
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr2_-_225434538 0.40 ENST00000409096.1
CUL3
cullin 3
chr22_+_44427230 0.39 ENST00000444029.1
PARVB
parvin, beta
chr11_-_10879593 0.39 ENST00000528289.1
ENST00000432999.2
ZBED5
zinc finger, BED-type containing 5
chr11_+_12115543 0.39 ENST00000537344.1
ENST00000532179.1
ENST00000526065.1
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr4_-_111120334 0.38 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr5_-_122758994 0.38 ENST00000306467.5
ENST00000515110.1
CEP120
centrosomal protein 120kDa
chr15_-_31283798 0.38 ENST00000435680.1
ENST00000425768.1
MTMR10
myotubularin related protein 10
chr1_-_241803679 0.37 ENST00000331838.5
OPN3
opsin 3
chr15_+_73344911 0.37 ENST00000560262.1
ENST00000558964.1
NEO1
neogenin 1
chr1_-_43855444 0.37 ENST00000372455.4
MED8
mediator complex subunit 8
chr1_+_203765437 0.37 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr2_+_152266392 0.37 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RIF1
RAP1 interacting factor homolog (yeast)
chr11_-_10879572 0.37 ENST00000413761.2
ZBED5
zinc finger, BED-type containing 5
chr6_+_4087664 0.37 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr10_-_118032697 0.36 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr1_+_95616933 0.36 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr3_+_112930946 0.35 ENST00000462425.1
BOC
BOC cell adhesion associated, oncogene regulated
chr5_-_64920115 0.35 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr20_+_18125727 0.35 ENST00000489634.2
CSRP2BP
CSRP2 binding protein
chr17_+_79953310 0.34 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr5_-_10308125 0.34 ENST00000296658.3
CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chr11_+_33061543 0.34 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr22_-_39928823 0.34 ENST00000334678.3
RPS19BP1
ribosomal protein S19 binding protein 1
chr8_+_101349823 0.34 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr1_-_31661000 0.34 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr2_+_74229812 0.34 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chr7_+_12250886 0.34 ENST00000444443.1
ENST00000396667.3
TMEM106B
transmembrane protein 106B
chr9_-_134585221 0.34 ENST00000372190.3
ENST00000427994.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr11_+_46639071 0.32 ENST00000580238.1
ENST00000581416.1
ENST00000529655.1
ENST00000533325.1
ENST00000581438.1
ENST00000583249.1
ENST00000530500.1
ENST00000526508.1
ENST00000578626.1
ENST00000577256.1
ENST00000524625.1
ENST00000582547.1
ENST00000359513.4
ENST00000528494.1
ATG13
autophagy related 13
chr3_-_185826855 0.32 ENST00000306376.5
ETV5
ets variant 5
chr7_-_27702455 0.31 ENST00000265395.2
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr2_-_86422523 0.31 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT
inner membrane protein, mitochondrial
chr14_+_23067146 0.31 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr2_-_128615517 0.31 ENST00000409698.1
POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
chr1_-_16400086 0.31 ENST00000375662.4
FAM131C
family with sequence similarity 131, member C
chr6_-_13621126 0.31 ENST00000600057.1
AL441883.1
Uncharacterized protein
chr12_-_58240470 0.31 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_-_12679171 0.31 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr17_-_30185946 0.31 ENST00000579741.1
COPRS
coordinator of PRMT5, differentiation stimulator
chr17_+_79213039 0.31 ENST00000431388.2
C17orf89
chromosome 17 open reading frame 89
chr12_+_96588279 0.30 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr15_+_49462434 0.30 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
GALK2
galactokinase 2
chr12_-_57472522 0.30 ENST00000379391.3
ENST00000300128.4
TMEM194A
transmembrane protein 194A
chr7_-_37026108 0.30 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr15_-_31283618 0.29 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr17_-_30185971 0.29 ENST00000378634.2
COPRS
coordinator of PRMT5, differentiation stimulator
chrX_-_19689106 0.29 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr19_-_42916499 0.29 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr7_-_6098770 0.28 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
chr17_-_79212825 0.28 ENST00000374769.2
ENTHD2
ENTH domain containing 2
chr1_+_117602925 0.28 ENST00000369466.4
TTF2
transcription termination factor, RNA polymerase II
chr4_+_105828537 0.28 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr19_+_50380682 0.28 ENST00000221543.5
TBC1D17
TBC1 domain family, member 17
chr7_+_76101379 0.28 ENST00000429179.1
DTX2
deltex homolog 2 (Drosophila)
chr12_-_100486668 0.28 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1BP1L
UHRF1 binding protein 1-like
chr14_+_102276209 0.27 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr19_+_50380917 0.27 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr14_-_102605983 0.27 ENST00000334701.7
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr11_+_33061336 0.27 ENST00000602733.1
TCP11L1
t-complex 11, testis-specific-like 1
chr11_-_94226964 0.27 ENST00000538923.1
ENST00000540013.1
ENST00000407439.3
ENST00000393241.4
MRE11A
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
chr13_-_31038370 0.27 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr9_-_88897426 0.26 ENST00000375991.4
ENST00000326094.4
ISCA1
iron-sulfur cluster assembly 1
chr17_-_67057047 0.26 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr1_-_168106536 0.26 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
GPR161
G protein-coupled receptor 161
chr2_-_197458323 0.26 ENST00000452031.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr3_-_28390298 0.25 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr5_+_60933634 0.25 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr9_-_136933615 0.25 ENST00000371834.2
BRD3
bromodomain containing 3
chr1_+_97188188 0.25 ENST00000541987.1
PTBP2
polypyrimidine tract binding protein 2
chr10_+_115469134 0.25 ENST00000452490.2
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr2_+_65283506 0.25 ENST00000377990.2
CEP68
centrosomal protein 68kDa
chr5_+_133706865 0.25 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr5_+_162932554 0.25 ENST00000321757.6
ENST00000421814.2
ENST00000518095.1
MAT2B
methionine adenosyltransferase II, beta
chr7_+_106505696 0.25 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr14_-_64108125 0.25 ENST00000267522.3
WDR89
WD repeat domain 89
chr11_-_94227029 0.25 ENST00000323977.3
ENST00000536754.1
ENST00000323929.3
MRE11A
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
chr1_+_28844778 0.25 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr5_+_79703823 0.25 ENST00000338008.5
ENST00000510158.1
ENST00000505560.1
ZFYVE16
zinc finger, FYVE domain containing 16
chr2_+_42104692 0.24 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr17_+_7533439 0.24 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr17_-_79212884 0.24 ENST00000300714.3
ENTHD2
ENTH domain containing 2
chr15_-_44828838 0.24 ENST00000560750.1
EIF3J-AS1
EIF3J antisense RNA 1 (head to head)
chr18_+_77160282 0.24 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr7_+_106505912 0.23 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr16_+_3333443 0.23 ENST00000572748.1
ENST00000573578.1
ENST00000574253.1
ZNF263
zinc finger protein 263

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.7 2.2 GO:0035623 renal glucose absorption(GO:0035623)
0.5 2.3 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.3 1.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.3 3.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 1.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 2.3 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 1.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.7 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 1.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 0.7 GO:0042391 regulation of membrane potential(GO:0042391)
0.2 1.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.9 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.8 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1 0.4 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.7 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.3 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.4 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 1.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 1.7 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.4 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.8 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.1 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 1.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.9 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.8 GO:0070836 caveola assembly(GO:0070836)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.5 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.3 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.2 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.6 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.7 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 1.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 2.1 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 1.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.7 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.5 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.9 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.8 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.0 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.0 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.6 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.3 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005712 chiasma(GO:0005712)
0.1 1.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 2.6 GO:0042588 zymogen granule(GO:0042588)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.7 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 4.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.7 GO:0001940 male pronucleus(GO:0001940)
0.1 0.5 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 2.2 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.7 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 0.7 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 1.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2 2.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 3.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.7 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.6 GO:0097001 ceramide binding(GO:0097001)
0.1 0.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.9 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.5 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.5 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 2.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 2.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0042979 ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 2.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.0 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.7 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.8 GO:0003823 antigen binding(GO:0003823)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 1.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.7 PID ATM PATHWAY ATM pathway
0.0 2.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 4.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.8 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions